Kyrre Eeg Emblem
Position: Principal investigator, PhD
Phone: +47 23 07 01 46
Email:
 

Author network for Kyrre Eeg Emblem by COREMINE medical


Publications 2017

Digernes I, Bjørnerud A, Vatnehol SAS, Løvland G, Courivaud F, Vik-Mo E, Meling TR, Emblem KE (2017)
A theoretical framework for determining cerebral vascular function and heterogeneity from dynamic susceptibility contrast MRI
J Cereb Blood Flow Metab, 37 (6), 2237-2248
PubMed 28273722

Publications 2016

Emblem KE, Jain RK (2016)
Improving treatment of liver metastases by targeting nonangiogenic mechanisms
Nat Med, 22 (11), 1209-1210
PubMed 27824818

Kalpathy-Cramer J, Chandra V, Da X, Ou Y, Emblem KE, Muzikansky A, Cai X, Douw L, Evans JG, Dietrich J, Chi AS, Wen PY, Stufflebeam S, Rosen B, Duda DG, Jain RK, Batchelor TT, Gerstner ER (2016)
Phase II study of tivozanib, an oral VEGFR inhibitor, in patients with recurrent glioblastoma
J Neurooncol, 131 (3), 603-610
PubMed 27853960

Publications 2015

Gerstner ER, Emblem KE, Sorensen GA (2015)
Vascular Magnetic Resonance Imaging in Brain Tumors During Antiangiogenic Therapy--Are We There Yet?
Cancer J, 21 (4), 337-42
PubMed 26222087

Heck A, Emblem KE, Casar-Borota O, Bollerslev J, Ringstad G (2015)
Quantitative analyses of T2-weighted MRI as a potential marker for response to somatostatin analogs in newly diagnosed acromegaly
Endocrine, 52 (2), 333-43
PubMed 26475495

Heck A, Emblem KE, Casar-Borota O, Ringstad G, Bollerslev J (2015)
MRI T2 characteristics in somatotroph adenomas following somatostatin analog treatment in acromegaly
Endocrine, 53 (1), 327-30
PubMed 26615593

Jafari-Khouzani K, Emblem KE, Kalpathy-Cramer J, Bjørnerud A, Vangel MG, Gerstner ER, Schmainda KM, Paynabar K, Wu O, Wen PY, Batchelor T, Rosen B, Stufflebeam SM (2015)
Repeatability of Cerebral Perfusion Using Dynamic Susceptibility Contrast MRI in Glioblastoma Patients
Transl Oncol, 8 (3), 137-46
PubMed 26055170

Juuhl-Langseth M, Hartberg CB, Holmén A, Thormodsen R, Groote IR, Rimol LM, Emblem KE, Agartz I, Rund BR (2015)
Impaired Verbal Learning Is Associated with Larger Caudate Volumes in Early Onset Schizophrenia Spectrum Disorders
PLoS One, 10 (7), e0130435
PubMed 26230626

Lu-Emerson C, Duda DG, Emblem KE, Taylor JW, Gerstner ER, Loeffler JS, Batchelor TT, Jain RK (2015)
Lessons from anti-vascular endothelial growth factor and anti-vascular endothelial growth factor receptor trials in patients with glioblastoma
J Clin Oncol, 33 (10), 1197-213
PubMed 25713439

Ringstad G, Emblem KE, Eide PK (2015)
Phase-contrast magnetic resonance imaging reveals net retrograde aqueductal flow in idiopathic normal pressure hydrocephalus
J Neurosurg, 124 (6), 1850-7
PubMed 26636385

Ringstad G, Emblem KE, Geier O, Alperin N, Eide PK (2015)
Reply: To PMID 25977480
AJNR Am J Neuroradiol, 36 (9), 1633-4
PubMed 26251437

Ringstad G, Emblem KE, Geier O, Alperin N, Eide PK (2015)
Aqueductal Stroke Volume: Comparisons with Intracranial Pressure Scores in Idiopathic Normal Pressure Hydrocephalus
AJNR Am J Neuroradiol, 36 (9), 1623-30
PubMed 25977480

Publications 2014

Brabrand K, de Lange C, Emblem KE, Reinholt FP, Saugstad OD, Stokke ES, Munkeby BH (2014)
Contrast-enhanced ultrasound identifies reduced overall and regional renal perfusion during global hypoxia in piglets
Invest Radiol, 49 (8), 540-6
PubMed 24637585

Due-Tonnessen P, Rasmussen I, Berntsen EM, Bjornerud A, Emblem KE (2014)
Identifying the central sulcus in patients with intra-axial lesions: a multicenter study comparing conventional presurgical MRI to topographical analysis and BOLD-fMRI
J Comput Assist Tomogr, 38 (1), 1-8
PubMed 24378889

Emblem KE, Farrar CT, Gerstner ER, Batchelor TT, Borra RJ, Rosen BR, Sorensen AG, Jain RK (2014)
Vessel caliber--a potential MRI biomarker of tumour response in clinical trials
Nat Rev Clin Oncol, 11 (10), 566-84
PubMed 25113840

Emblem KE, Pinho MC, Zöllner FG, Due-Tonnessen P, Hald JK, Schad LR, Meling TR, Rapalino O, Bjornerud A (2014)
A generic support vector machine model for preoperative glioma survival associations
Radiology, 275 (1), 228-34
PubMed 25486589

Kalpathy-Cramer J, Gerstner ER, Emblem KE, Andronesi OC, Rosen B (2014)
Advanced magnetic resonance imaging of the physical processes in human glioblastoma
Cancer Res, 74 (17), 4622-37
PubMed 25183787

Publications 2013

Batchelor TT, Gerstner ER, Emblem KE, Duda DG, Kalpathy-Cramer J, Snuderl M, Ancukiewicz M, Polaskova P, Pinho MC, Jennings D, Plotkin SR, Chi AS, Eichler AF, Dietrich J, Hochberg FH, Lu-Emerson C, Iafrate AJ, Ivy SP, Rosen BR, Loeffler JS, Wen PY, Sorensen AG, Jain RK (2013)
Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation
Proc Natl Acad Sci U S A, 110 (47), 19059-64
PubMed 24190997

Emblem KE, Due-Tonnessen P, Hald JK, Bjornerud A, Pinho MC, Scheie D, Schad LR, Meling TR, Zoellner FG (2013)
Machine learning in preoperative glioma MRI: survival associations by perfusion-based support vector machine outperforms traditional MRI
J Magn Reson Imaging, 40 (1), 47-54
PubMed 24753371

Emblem KE, Mouridsen K, Bjornerud A, Farrar CT, Jennings D, Borra RJ, Wen PY, Ivy P, Batchelor TT, Rosen BR, Jain RK, Sorensen AG (2013)
Vessel architectural imaging identifies cancer patient responders to anti-angiogenic therapy
Nat Med, 19 (9), 1178-83
PubMed 23955713

Pinho MC, Polaskova P, Kalpathy-Cramer J, Jennings D, Emblem KE, Jain RK, Rosen BR, Wen PY, Sorensen AG, Batchelor TT, Gerstner ER (2013)
Low incidence of pseudoprogression by imaging in newly diagnosed glioblastoma patients treated with cediranib in combination with chemoradiation
Oncologist, 19 (1), 75-81
PubMed 24309981

Thormodsen R, Rimol LM, Tamnes CK, Juuhl-Langseth M, Holmén A, Emblem KE, Rund BR, Agartz I (2013)
Age-related cortical thickness differences in adolescents with early-onset schizophrenia compared with healthy adolescents
Psychiatry Res, 214 (3), 190-6
PubMed 24144503

Publications 2012

Juuhl-Langseth M, Rimol LM, Rasmussen IA, Thormodsen R, Holmén A, Emblem KE, Due-Tønnessen P, Rund BR, Agartz I (2012)
Comprehensive segmentation of subcortical brain volumes in early onset schizophrenia reveals limited structural abnormalities
Psychiatry Res, 203 (1), 14-23
PubMed 22917502

Zöllner FG, Emblem KE, Schad LR (2012)
SVM-based glioma grading: Optimization by feature reduction analysis
Z Med Phys, 22 (3), 205-14
PubMed 22503911

Publications 2011

Bjornerud A, Sorensen AG, Mouridsen K, Emblem KE (2011)
T1- and T2*-dominant extravasation correction in DSC-MRI: part I--theoretical considerations and implications for assessment of tumor hemodynamic properties
J Cereb Blood Flow Metab, 31 (10), 2041-53
PubMed 21505483

de Lange C, Brabrand K, Emblem KE, Bjornerud A, Løberg EM, Saugstad OD, Munkeby BH (2011)
Cerebral perfusion in perinatal hypoxia and resuscitation assessed by transcranial contrast-enhanced ultrasound and 3 T MRI in newborn pigs
Invest Radiol, 46 (11), 686-96
PubMed 21730873

Emblem KE, Bjornerud A, Mouridsen K, Borra RJ, Batchelor TT, Jain RK, Sorensen AG (2011)
T(1)- and T(2)(*)-dominant extravasation correction in DSC-MRI: part II-predicting patient outcome after a single dose of cediranib in recurrent glioblastoma patients
J Cereb Blood Flow Metab, 31 (10), 2054-64
PubMed 21505476

Garzón B, Emblem KE, Mouridsen K, Nedregaard B, Due-Tønnessen P, Nome T, Hald JK, Bjørnerud A, Håberg AK, Kvinnsland Y (2011)
Multiparametric analysis of magnetic resonance images for glioma grading and patient survival time prediction
Acta Radiol, 52 (9), 1052-60
PubMed 21969702

Ringstad GA, Emblem KE, Holland D, Dale AM, Bjornerud A, Hald JK (2011)
Assessment of pituitary adenoma volumetric change using longitudinal MR image registration
Neuroradiology, 54 (5), 435-43
PubMed 21647587

Sorensen AG, Emblem KE, Polaskova P, Jennings D, Kim H, Ancukiewicz M, Wang M, Wen PY, Ivy P, Batchelor TT, Jain RK (2011)
Increased survival of glioblastoma patients who respond to antiangiogenic therapy with elevated blood perfusion
Cancer Res, 72 (2), 402-7
PubMed 22127927

Thormodsen R, Jensen J, Holmèn A, Juuhl-Langseth M, Emblem KE, Andreassen OA, Rund BR (2011)
Prefrontal hyperactivation during a working memory task in early-onset schizophrenia spectrum disorders: an fMRI study
Psychiatry Res, 194 (3), 257-62
PubMed 22079661

Publications 2010

Bjørnerud A, Emblem KE (2010)
A fully automated method for quantitative cerebral hemodynamic analysis using DSC-MRI
J Cereb Blood Flow Metab, 30 (5), 1066-78
PubMed 20087370

Zöllner FG, Emblem KE, Schad LR (2010)
Support vector machines in DSC-based glioma imaging: suggestions for optimal characterization
Magn Reson Med, 64 (4), 1230-6
PubMed 20564592

Publications 2009

Emblem KE, Bjornerud A (2009)
An automatic procedure for normalization of cerebral blood volume maps in dynamic susceptibility contrast-based glioma imaging
AJNR Am J Neuroradiol, 30 (10), 1929-32
PubMed 19628627

Emblem KE, Due-Tonnessen P, Hald JK, Bjornerud A (2009)
Automatic vessel removal in gliomas from dynamic susceptibility contrast imaging
Magn Reson Med, 61 (5), 1210-7
PubMed 19253390

Emblem KE, Nedregaard B, Hald JK, Nome T, Due-Tonnessen P, Bjornerud A (2009)
Automatic glioma characterization from dynamic susceptibility contrast imaging: brain tumor segmentation using knowledge-based fuzzy clustering
J Magn Reson Imaging, 30 (1), 1-10
PubMed 19557840

Publications 2008

Emblem KE, Nedregaard B, Nome T, Due-Tonnessen P, Hald JK, Scheie D, Borota OC, Cvancarova M, Bjornerud A (2008)
Glioma grading by using histogram analysis of blood volume heterogeneity from MR-derived cerebral blood volume maps
Radiology, 247 (3), 808-17
PubMed 18487536

Emblem KE, Scheie D, Due-Tonnessen P, Nedregaard B, Nome T, Hald JK, Beiske K, Meling TR, Bjornerud A (2008)
Histogram analysis of MR imaging-derived cerebral blood volume maps: combined glioma grading and identification of low-grade oligodendroglial subtypes
AJNR Am J Neuroradiol, 29 (9), 1664-70
PubMed 18583405

Emblem KE, Zoellner FG, Tennoe B, Nedregaard B, Nome T, Due-Tonnessen P, Hald JK, Scheie D, Bjornerud A (2008)
Predictive modeling in glioma grading from MR perfusion images using support vector machines
Magn Reson Med, 60 (4), 945-52
PubMed 18816815

Munkeby BH, De Lange C, Emblem KE, Bjørnerud A, Kro GA, Andresen J, Winther-Larssen EH, Løberg EM, Hald JK (2008)
A piglet model for detection of hypoxic-ischemic brain injury with magnetic resonance imaging
Acta Radiol, 49 (9), 1049-57
PubMed 18720081