Morten Pedersen Oksvold
Position: Scientist, PhD
Phone: (+47) 22781424
Email:

Mini CV:

Education:

2004 PhD (Dr. Philos), University of Oslo. Thesis: ”Trafficking of and signaling from the epidermal growth factor receptor after ligand and stress exposure”.

1996 Ms, University of Oslo. Title: ” A morphological and kinetic study of large vesicular structures in MDCK cells transfected with invariant chain”

Research interests:

• Trafficking of and signaling from BMP/TGF-beta receptors in B-cell lymphoma
• Intracellular localization of signaling molecules down stream of BMP/TGF-beta
receptors
• Confocal immunofluorescence microscopy combined with flow cytometry

Previous employment:

2004-2007 Post doc, Institute of Pathology, Rikshospitalet University Hospital, University of Oslo.

 

Author network for Morten Pedersen Oksvold by COREMINE medical


Publications 2015

Oksvold MP (2015)
Incidence of Data Duplications in a Randomly Selected Pool of Life Science Publications
Sci Eng Ethics, 22 (2), 487-96
PubMed 26065681

Oksvold MP, Duyvestyn JM, Dagger SA, Taylor SJ, Forfang L, Myklebust JH, Smeland EB, Langdon WY (2015)
The targeting of human and mouse B lymphocytes by dasatinib
Exp Hematol, 43 (5), 352-363.e4
PubMed 25641047

Oksvold MP, Neurauter A, Pedersen KW (2015)
Magnetic bead-based isolation of exosomes
Methods Mol Biol, 1218, 465-81
PubMed 25319668

Publications 2014

Oksvold MP, Kullmann A, Forfang L, Kierulf B, Li M, Brech A, Vlassov AV, Smeland EB, Neurauter A, Pedersen KW (2014)
Expression of B-cell surface antigens in subpopulations of exosomes released from B-cell lymphoma cells
Clin Ther, 36 (6), 847-862.e1
PubMed 24952935

Publications 2012

Bakkebø M, Huse K, Hilden VI, Forfang L, Myklebust JH, Smeland EB, Oksvold MP (2012)
SARA is dispensable for functional TGF-β signaling
FEBS Lett, 586 (19), 3367-72
PubMed 22819827

Huse K, Bakkebø M, Wälchli S, Oksvold MP, Hilden VI, Forfang L, Bredahl ML, Liestøl K, Alizadeh AA, Smeland EB, Myklebust JH (2012)
Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma
PLoS One, 7 (10), e46117
PubMed 23049692

Oksvold MP, Pedersen NM, Forfang L, Smeland EB (2012)
Effect of cycloheximide on epidermal growth factor receptor trafficking and signaling
FEBS Lett, 586 (20), 3575-81
PubMed 22971756

Publications 2011

Huse K, Bakkebø M, Oksvold MP, Forfang L, Hilden VI, Stokke T, Smeland EB, Myklebust JH (2011)
Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: differential effects of BMP-6 and BMP-7
Eur J Immunol, 41 (11), 3135-45
PubMed 21898381

Publications 2010

Bakkebø M, Huse K, Hilden VI, Smeland EB, Oksvold MP (2010)
TGF-β-induced growth inhibition in B-cell lymphoma correlates with Smad1/5 signalling and constitutively active p38 MAPK
BMC Immunol, 11, 57
PubMed 21092277

Publications 2008

Oksvold MP, Funderud A, Kvissel AK, Skarpen E, Henanger H, Huitfeldt HS, Skålhegg BS, Ørstavik S (2008)
Epidermal growth factor receptor levels are reduced in mice with targeted disruption of the protein kinase A catalytic subunit
BMC Cell Biol, 9, 16
PubMed 18380891

Rosseland CM, Wierød L, Flinder LI, Oksvold MP, Skarpen E, Huitfeldt HS (2008)
Distinct functions of H-Ras and K-Ras in proliferation and survival of primary hepatocytes due to selective activation of ERK and PI3K
J Cell Physiol, 215 (3), 818-26
PubMed 18163378

Publications 2007

Oksvold MP, Dagger SA, Thien CB, Langdon WY (2007)
The Cbl-b RING finger domain has a limited role in regulating inflammatory cytokine production by IgE-activated mast cells
Mol Immunol, 45 (4), 925-36
PubMed 17868870

Skarpen E, Flinder LI, Rosseland CM, Orstavik S, Wierød L, Oksvold MP, Skålhegg BS, Huitfeldt HS (2007)
MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments
FASEB J, 22 (2), 466-76
PubMed 17928366

Wierød L, Rosseland CM, Lindeman B, Oksvold MP, Grøsvik H, Skarpen E, Huitfeldt HS (2007)
Activation of the p53-p21(Cip1) pathway is required for CDK2 activation and S-phase entry in primary rat hepatocytes
Oncogene, 27 (19), 2763-71
PubMed 18026139

Wierød L, Rosseland CM, Lindeman B, Oksvold MP, Grøsvik H, Skarpen E, Huitfeldt HS (2007)
CDK2 regulation through PI3K and CDK4 is necessary for cell cycle progression of primary rat hepatocytes
Cell Prolif, 40 (4), 475-87
PubMed 17635516

Publications 2005

Paasche JD, Attramadal T, Kristiansen K, Oksvold MP, Johansen HK, Huitfeldt HS, Dahl SG, Attramadal H (2005)
Subtype-specific sorting of the ETA endothelin receptor by a novel endocytic recycling signal for G protein-coupled receptors
Mol Pharmacol, 67 (5), 1581-90
PubMed 15713850

Rosseland CM, Wierød L, Oksvold MP, Werner H, Ostvold AC, Thoresen GH, Paulsen RE, Huitfeldt HS, Skarpen E (2005)
Cytoplasmic retention of peroxide-activated ERK provides survival in primary cultures of rat hepatocytes
Hepatology, 42 (1), 200-7
PubMed 15962331

Skarpen E, Oksvold MP, Grøsvik H, Widnes C, Huitfeldt HS (2005)
Altered regulation of EGF receptor signaling following a partial hepatectomy
J Cell Physiol, 202 (3), 707-16
PubMed 15389569

Publications 2004

Oksvold MP, Huitfeldt HS, Langdon WY (2004)
Identification of 14-3-3zeta as an EGF receptor interacting protein
FEBS Lett, 569 (1-3), 207-10
PubMed 15225635

Oksvold MP, Thien CB, Widerberg J, Chantry A, Huitfeldt HS, Langdon WY (2004)
UV-radiation-induced internalization of the epidermal growth factor receptor requires distinct serine and tyrosine residues in the cytoplasmic carboxy-terminal domain
Radiat Res, 161 (6), 685-91
PubMed 15161351

Publications 2003

Oksvold MP, Thien CB, Widerberg J, Chantry A, Huitfeldt HS, Langdon WY (2003)
Serine mutations that abrogate ligand-induced ubiquitination and internalization of the EGF receptor do not affect c-Cbl association with the receptor
Oncogene, 22 (52), 8509-18
PubMed 14627991

Publications 2002

Oksvold M, Huitfeldt H, Stang E, Madshus I (2002)
Localizing the EGF receptor
Nat Cell Biol, 4 (2), E22; author reply E22-3
PubMed 11835048

Oksvold MP, Huitfeldt HS, Østvold AC, Skarpen E (2002)
UV induces tyrosine kinase-independent internalisation and endosome arrest of the EGF receptor
J Cell Sci, 115 (Pt 4), 793-803
PubMed 11865035

Oksvold MP, Skarpen E, Widerberg J, Huitfeldt HS (2002)
Fluorescent histochemical techniques for analysis of intracellular signaling
J Histochem Cytochem, 50 (3), 289-303
PubMed 11850432

Publications 2001

Oksvold MP, Skarpen E, Wierød L, Paulsen RE, Huitfeldt HS (2001)
Re-localization of activated EGF receptor and its signal transducers to multivesicular compartments downstream of early endosomes in response to EGF
Eur J Cell Biol, 80 (4), 285-94
PubMed 11370743

Publications 2000

Lindeman B, Skarpen E, Oksvold MP, Huitfeldt HS (2000)
The carcinogen 2-acetylaminofluorene inhibits activation and nuclear accumulation of cyclin-dependent kinase 2 in growth-induced rat liver
Mol Carcinog, 27 (3), 190-9
PubMed 10708481

Oksvold MP, Skarpen E, Lindeman B, Roos N, Huitfeldt HS (2000)
Immunocytochemical localization of Shc and activated EGF receptor in early endosomes after EGF stimulation of HeLa cells
J Histochem Cytochem, 48 (1), 21-33
PubMed 10653583

Skarpen E, Lindeman B, Thoresen GH, Guren TK, Oksvold MP, Christoffersen T, Huitfeldt HS (2000)
Impaired nuclear accumulation and shortened phosphorylation of ERK after growth factor stimulation in cultured hepatocytes from rats exposed to 2-acetylaminofluorene
Mol Carcinog, 28 (2), 84-96
PubMed 10900465

Publications 1999

Huitfeldt HS, Lindeman B, Skarpen E, Oksvold MP, Wierød L (1999)
[Why is dioxin harmful?]
Tidsskr Nor Laegeforen, 119 (29), 4323-8
PubMed 10667131

Publications 1998

Saebøe-Larssen S, Lyamouri M, Merriam J, Oksvold MP, Lambertsson A (1998)
Ribosomal protein insufficiency and the minute syndrome in Drosophila: a dose-response relationship
Genetics, 148 (3), 1215-24
PubMed 9539436