| June Helen Myklebust | |
| Position: | Post doc |
| Phone: | +47 22781413 |
| Email: | |
Mini CV:
Education:
2001: PhD, University of Oslo. Thesis: “Regulation of differentiation and apoptosis in human bone marrow hematopoietic progenitor cells.”
1993: Ms, University of Trondheim. Diploma thesis: “Radiation-induced changes in murine fibrosarcoma cells grown in culture.”
Research interests/projects:
- The influence of microenvironment in B cell lymphomas
- The impact of BMP signaling in B cell lymphomas
- Multiparameter FACS analysis for characterization of intracellular signaling pathways in B cell lymphomas
Work experience
2003-present: Postdoctoral fellow at Department of Immunology, The Norwegian Cancer Society fellowship
2002-2003: Postdoctoral fellow at Department of Immunology, The Norwegian Radium Hospital
1996-2001: Ph.D student at Department of Immunology, The Norwegian Radium Hospital
1994-1995: Technician at Dynal Biotech AS
Author network for June Helen Myklebust by COREMINE medical
Publications 2011
Prediction of survival in diffuse large B-cell lymphoma based on the expression of 2 genes reflecting tumor and microenvironment
Blood, 118 (5), 1350-8
PubMed 21670469
Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: differential effects of BMP-6 and BMP-7
Eur J Immunol, 41 (11), 3135-45
PubMed 21898381
The amount of DNA damage needed to activate the radiation-induced G2 checkpoint varies between single cells
Radiother Oncol, 101 (1), 24-7
PubMed 21722983
Publications 2010
Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma
Cell, 142 (5), 699-713
PubMed 20813259
B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression
Proc Natl Acad Sci U S A, 107 (29), 12747-54
PubMed 20543139
CD81 protein is expressed at high levels in normal germinal center B cells and in subtypes of human lymphomas
Hum Pathol, 41 (2), 271-80
PubMed 20004001
Publications 2009
A pluripotency signature predicts histologic transformation and influences survival in follicular lymphoma patients
Blood, 114 (15), 3158-66
PubMed 19636063
Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion
Blood, 114 (16), 3431-8
PubMed 19641184
Publications 2007
Expression of S100A4 by a variety of cell types present in the tumor microenvironment of human breast cancer
Int J Cancer, 121 (7), 1433-44
PubMed 17565747
Characterization of early stages of human B cell development by gene expression profiling
J Immunol, 179 (6), 3662-71
PubMed 17785802
Inhibitory effects and target genes of bone morphogenetic protein 6 in Jurkat TAg cells
Eur J Immunol, 37 (10), 2937-48
PubMed 17899540
Publications 2006
BMP-6 inhibits human bone marrow B lymphopoiesis--upregulation of Id1 and Id3
Exp Hematol, 34 (1), 72-81
PubMed 16413393
PI3K/Akt-dependent Epo-induced signalling and target genes in human early erythroid progenitor cells
Br J Haematol, 135 (1), 117-28
PubMed 16965383
Publications 2005
BMP-6 inhibits growth of mature human B cells; induction of Smad phosphorylation and upregulation of Id1
BMC Immunol, 6, 9
PubMed 15877825
PU.1 protein expression has a positive linear association with protein expression of germinal centre B cell genes including BCL-6, CD10, CD20 and CD22: identification of PU.1 putative binding sites in the BCL-6 promotor
J Pathol, 206 (3), 312-9
PubMed 15892171
Publications 2002
Activation of phosphatidylinositol 3-kinase is important for erythropoietin-induced erythropoiesis from CD34(+) hematopoietic progenitor cells
Exp Hematol, 30 (9), 990-1000
PubMed 12225790
Publications 2000
Differential expression of bcl-2 homologs in human CD34(+) hematopoietic progenitor cells induced to differentiate into erythroid or granulocytic cells
Stem Cells, 18 (4), 261-72
PubMed 10924092
Protein kinase C-alpha isoform is involved in erythropoietin-induced erythroid differentiation of CD34(+) progenitor cells from human bone marrow
Blood, 95 (2), 510-8
PubMed 10627456
Publications 1999
Relation between S-phase fraction of myeloma cells and anemia in patients with multiple myeloma
Exp Hematol, 27 (11), 1621-6
PubMed 10560909
Fas ligand promotes cell survival of immature human bone marrow CD34+CD38- hematopoietic progenitor cells by suppressing apoptosis
Exp Hematol, 27 (9), 1451-9
PubMed 10480436
Activation of the cAMP signaling pathway increases apoptosis in human B-precursor cells and is associated with downregulation of Mcl-1 expression
J Cell Physiol, 180 (1), 71-80
PubMed 10362019
Publications 1998
Generation and characterization of gp100 peptide-specific NK-T cell clones
Int J Cancer, 75 (5), 794-803
PubMed 9495251




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