
| Steinar Aamdal | |
| Position: | MD PhD/ Head of section |
| Phone: | +47 22934000 |
| Email: | |
Publications by Steinar Aamdal
91 publications found
Publications in press
-
Health-related quality of life in patients with high-risk melanoma randomised in the Nordic phase 3 trial with adjuvant intermediate-dose interferon alfa-2b
Eur J Cancer (in press)
PubMed 22196968 -
Phase I study of saracatinib (AZD0530) in combination with paclitaxel and/or carboplatin in patients with solid tumours
Br J Cancer (in press)
PubMed 22531637
Publications 2011
-
Telomerase peptide vaccination in NSCLC: a phase II trial in stage III patients vaccinated after chemoradiotherapy and an 8-year update on a phase I/II trial
Clin Cancer Res, 17 (21), 6847-57
PubMed 21918169 -
Defining the critical hurdles in cancer immunotherapy
J Transl Med, 9 (1), 214
PubMed 22168571 -
A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma
J Transl Med, 9, 204
PubMed 22123319 -
Two different durations of adjuvant therapy with intermediate-dose interferon alfa-2b in patients with high-risk melanoma (Nordic IFN trial): a randomised phase 3 trial
Lancet Oncol, 12 (2), 144-52
PubMed 21256809 -
Telomerase peptide vaccination combined with temozolomide: a clinical trial in stage IV melanoma patients
Clin Cancer Res, 17 (13), 4568-80
PubMed 21586625 -
hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes
Cancer Immunol Immunother, 60 (6), 809-18
PubMed 21365467 -
The preclinical and clinical activity of aviscumine: a potential anticancer drug
Eur J Cancer, 47 (10), 1450-7
PubMed 21482461 -
Current approaches to adjuvant therapy of melanoma
Eur J Cancer, 47 Suppl 3, S336-7
PubMed 21944005
Publications 2010
-
SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance
Pharmacogenomics J, 10 (6), 513-23
PubMed 20157331 -
Human malignant melanoma harbours a large fraction of highly clonogenic cells that do not express markers associated with cancer stem cells
Pigment Cell Melanoma Res, 23 (3), 449-51
PubMed 20236249
Publications 2009
-
Autoimmune antibodies and recurrence-free interval in melanoma patients treated with adjuvant interferon
J Natl Cancer Inst, 101 (12), 869-77
PubMed 19509353 -
Intravenous administration of CP-4055 (ELACYT) in patients with solid tumours. A Phase I study
Acta Oncol, 48 (1), 137-45
PubMed 18607882 -
Assessing quality of life in a randomized clinical trial: correcting for missing data
BMC Med Res Methodol, 9, 28
PubMed 19405936
Publications 2008
-
Bone marrow micrometastases in advanced stage non-small cell lung carcinoma patients
Lung Cancer, 61 (2), 170-6
PubMed 18261824 -
S100B in bone marrow aspirates in healthy individuals and malignant melanoma patients
Melanoma Res, 18 (2), 134-40
PubMed 18337650 -
Population-based prevalence of CDKN2A and CDK4 mutations in patients with multiple primary melanomas
Genes Chromosomes Cancer, 47 (2), 175-84
PubMed 18023021
Publications 2007
-
Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy
BMC Cancer, 7, 197
PubMed 17956601 -
The prognostic role of blood lymphocyte subset distribution in patients with resected high-risk primary or regionally metastatic melanoma
J Immunother, 30 (7), 773-9
PubMed 17893569 -
T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells
Cancer Immunol Immunother, 56 (5), 659-75
PubMed 16947019
Publications 2006
-
High sensitivity assays for docetaxel and paclitaxel in plasma using solid-phase extraction and high-performance liquid chromatography with UV detection
BMC Clin Pharmacol, 6, 2
PubMed 16412237 -
Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer
Cancer Immunol Immunother, 55 (12), 1553-64
PubMed 16491401 -
[Malignant melanoma--diagnosis and treatment]
Tidsskr Nor Laegeforen, 126 (23), 3094-7
PubMed 17160112 -
Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
Cancer Gene Ther, 13 (10), 905-18
PubMed 16710345 -
[Retraction of: Diagnostics and treatment of early stages of oral cancer]
Tidsskr Nor Laegeforen, 126 (17), 2287
PubMed 16967079
Publications 2005
-
Weekly docetaxel with concurrent radiotherapy in locally advanced non-small cell lung cancer: a phase I/II study with 5 years' follow-up
Lung Cancer, 50 (1), 97-105
PubMed 16005105 -
Preclinical full-scale evaluation of dendritic cells transfected with autologous tumor-mRNA for melanoma vaccination
Cancer Gene Ther, 12 (6), 579-91
PubMed 15818380 -
Multi-centre Phase II trial of the polyamine synthesis inhibitor SAM486A (CGP48664) in patients with metastatic melanoma
Invest New Drugs, 23 (3), 253-6
PubMed 15868382 -
Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients
Br J Cancer, 93 (7), 749-56
PubMed 16136047 -
Phase II study of E7070 in patients with metastatic melanoma
Ann Oncol, 16 (1), 158-61
PubMed 15598954 -
Second-line chemotherapy in recurrent small cell lung cancer. Results from a crossover schedule after primary treatment with cisplatin and etoposide (EP-regimen) or cyclophosphamide, epirubicin, and vincristin (CEV-regimen)
Lung Cancer, 48 (2), 251-61
PubMed 15829326
Publications 2004
-
Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: a phase III study
J Clin Oncol, 22 (6), 1118-25
PubMed 15020614 -
Development of an optimal sampling strategy for clinical pharmacokinetic studies of the novel anthracycline disaccharide analogue MEN-10755
Cancer Chemother Pharmacol, 54 (1), 64-70
PubMed 15069581 -
Individualized patient dosing in phase I clinical trials: the role of escalation with overdose control in PNU-214936
J Clin Oncol, 22 (4), 602-9
PubMed 14966084 -
Immunomagnetic detection and clinical significance of micrometastatic tumor cells in malignant melanoma patients
Clin Cancer Res, 10 (12 Pt 1), 4134-9
PubMed 15217950 -
Hypofractionated palliative radiotherapy (17 Gy per two fractions) in advanced non-small-cell lung carcinoma is comparable to standard fractionation for symptom control and survival: a national phase III trial
J Clin Oncol, 22 (5), 801-10
PubMed 14990635
Publications 2003
-
The value of prognostic factors in small cell lung cancer: results from a randomised multicenter study with minimum 5 year follow-up
Lung Cancer, 39 (3), 303-13
PubMed 12609569 -
Immunisation of metastatic cancer patients with MAGE-3 protein combined with adjuvant SBAS-2: a clinical report
Eur J Cancer, 39 (1), 70-7
PubMed 12504661
Publications 2002
-
Cisplatin and etoposide regimen is superior to cyclophosphamide, epirubicin, and vincristine regimen in small-cell lung cancer: results from a randomized phase III trial with 5 years' follow-up
J Clin Oncol, 20 (24), 4665-72
PubMed 12488411
Publications 2001
-
Pharmacokinetics of MEN-10755, a novel anthracycline disaccharide analogue, in two phase I studies in adults with advanced solid tumours
Cancer Chemother Pharmacol, 48 (5), 361-9
PubMed 11761453 -
Immunobead-based detection and characterization of circulating tumor cells in melanoma patients
Recent Results Cancer Res, 158, 40-50
PubMed 11092032 -
[Gene therapy in cancer]
Tidsskr Nor Laegeforen, 121 (4), 482-8
PubMed 11255868 -
[Diagnosis and treatment of oral precancerous lesions]
Tidsskr Nor Laegeforen, 121 (26), 3066-71 (Retracted)
PubMed 11757442
Publications 2000
-
Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma
J Clin Oncol, 18 (1), 158-66
PubMed 10623706 -
Carzelesin phase II study in advanced breast, ovarian, colorectal, gastric, head and neck cancer, non-Hodgkin's lymphoma and malignant melanoma: a study of the EORTC early clinical studies group (ECSG)
Cancer Chemother Pharmacol, 46 (2), 167-71
PubMed 10972487 -
Phase I trial with weekly EO9, a novel bioreductive alkylating indoloquinone, by the EORTC Early Clinical Study Group (ECSG)
Cancer Chemother Pharmacol, 45 (1), 85-8
PubMed 10647507
Publications 1998
-
Dacarbazine-vindesine versus dacarbazine-vindesine-cisplatin in disseminated malignant melanoma. A randomised phase III trial
Eur J Cancer, 34 (9), 1368-74
PubMed 9849419 -
Clinical experience of fotemustine, cisplatin and high dose tamoxifen in patients with metastatic malignant melanoma
Melanoma Res, 8 (6), 565-72
PubMed 9918419 -
Zilascorb(H-2), a low-toxicity protein synthesis inhibitor that exhibits signs of anticancer activity in malignant melanoma
Anti-Cancer Drugs, 9 (9), 797-802 -
Zilascorb(2H), a low-toxicity protein synthesis inhibitor that exhibits signs of anticancer activity in malignant melanoma
Anticancer Drugs, 9 (9), 797-802
PubMed 9840726 -
Capillary protein leak syndrome appears to explain fluid retention in cancer patients who receive docetaxel treatment
J Clin Oncol, 16 (10), 3426-32
PubMed 9779722
Publications 1997
-
Zilascorb(H-2), a new reversible protein synthesis inhibitor: Clinical study of an oral preparation
Anti-Cancer Drugs, 8 (3), 296-303 -
Zilascorb(2H), a new reversible protein synthesis inhibitor: clinical study of an oral preparation
Anticancer Drugs, 8 (3), 296-303
PubMed 9095337 -
Zeniplatin in advanced malignant melanoma and renal cancer: phase II studies with unexpected nephrotoxicity
Cancer Chemother Pharmacol, 40 (5), 439-43
PubMed 9272122
Publications 1996
-
Phase II clinical trials with rhizoxin in breast cancer and melanoma. The EORTC Early Clinical Trials Group
Br J Cancer, 73 (3), 397-9
PubMed 8562349 -
Correlation of DNA ploidy and S-phase fraction with chemotherapeutic response and survival in a randomized study of disseminated malignant melanoma
Int J Cancer, 65 (1), 1-5
PubMed 8543385 -
Phase I pharmacokinetics and limited sampling strategies for the bioreductive alkylating drug EO9. EORTC Early Clinical Trials Group
Eur J Cancer, 32A (9), 1518-22
PubMed 8911111 -
Multicentre phase II pharmacological evaluation of rhizoxin. Eortc early clinical studies (ECSG)/pharmacology and molecular mechanisms (PAMM) groups
Br J Cancer, 74 (12), 1944-8
PubMed 8980394 -
Transcapillary forces of the subcutaneous tissue in patients treated with interleukin-2 and alpha-interferon: no capillary protein leak syndrome?
J Exp Ther Oncol, 1 (3), 155-61
PubMed 9414399
Publications 1995
-
Serum levels of cytokines and soluble cytokine receptors in patients with metastatic renal cell carcinoma or malignant melanoma receiving IL-2/interferon-alpha combination therapy
Acta Oncol, 34 (5), 599-603
PubMed 7546824 -
Phase II studies of docetaxel in the treatment of various solid tumours. EORTC Early Clinical Trials Group and the EORTC Soft Tissue and Bone Sarcoma Group
Eur J Cancer, 31A Suppl 4, S21-4
PubMed 7577101
Publications 1994
-
Gemcitabine in patients with advanced malignant melanoma or gastric cancer: phase II studies of the EORTC Early Clinical Trials Group
Ann Oncol, 5 (5), 471-2
PubMed 8075055 -
Clinical studies with EO9, a new indoloquinone bioreductive alkylating cytotoxic agent. EORTC Early Clinical Trials Group
Oncol Res, 6 (10-11), 519-23
PubMed 7620220 -
Docetaxel (Taxotere) in advanced malignant melanoma: a phase II study of the EORTC Early Clinical Trials Group
Eur J Cancer, 30A (8), 1061-4
PubMed 7654429
Publications 1993
-
Activity and unexpected lung toxicity of the sequential administration of two alkylating agents--dacarbazine and fotemustine--in patients with melanoma
Eur J Cancer, 29A (5), 711-9
PubMed 8471329 -
A double blind study to evaluate the tolerability of gadodiamide injection and its effect on renal function in patients undergoing cerebral magnetic resonance imaging
Br J Radiol, 66 (790), 871-6
PubMed 8220968
Publications 1992
-
Detection of bone marrow metastases in small cell lung cancer patients. Comparison of immunologic and morphologic methods
Am J Pathol, 141 (3), 531-8
PubMed 1381558 -
Levels of nm23 messenger RNA in metastatic malignant melanomas: inverse correlation to disease progression
Cancer Res, 52 (21), 6088-91
PubMed 1356624 -
Neuron-specific enolase as a prognostic factor in metastatic malignant melanoma
Eur J Cancer, 28A (10), 1692-5
PubMed 1389487 -
Can ondansetron hydrochloride (Zofran) enhance the nephrotoxic potential of other drugs?
Ann Oncol, 3 (9), 774
PubMed 1450070 -
Sequential administration of dacarbazine and fotemustine in patients with disseminated malignant melanoma--an effective combination with unexpected toxicity
Eur J Cancer, 28 (2-3), 447-50
PubMed 1591062
Publications 1991
-
Selection of anti-SCLC antibodies for diagnosis of bone marrow metastasis
Br J Cancer Suppl, 14, 49-53
PubMed 1645572 -
Sequential administration of recombinant human interleukin-2 and dacarbazine in metastatic melanoma: a multicenter phase II study
J Clin Oncol, 9 (9), 1687-91
PubMed 1875225
Publications 1990
-
Studies of the L-myc DNA polymorphism and relation to metastasis in Norwegian lung cancer patients
Br J Cancer, 61 (6), 809-12
PubMed 1973618 -
Neuron specific enolase (NSE) in serum of patients with malignant melanoma
Cancer Lett, 52 (1), 29-31
PubMed 2354416
Publications 1989
-
Sequential administration of recombinant human interleukin-2 and dacarbazine in metastatic melanoma. A multicentre phase II study
Eur J Cancer Clin Oncol, 25 Suppl 3, S41-3
PubMed 2697578
Publications 1988
-
Extrapulmonary, tissue-specific metastasis formation in nude mice injected with FEMX-I human melanoma cells
Cancer Res, 48 (15), 4382-8
PubMed 3390834 -
A new experimental metastasis model in athymic nude mice, the human malignant melanoma LOX
Int J Cancer, 41 (3), 442-9
PubMed 3346110 -
Sodium thiosulfate fails to increase the therapeutic index of intravenously administered cis-diamminedichloroplatinum (II) in mice bearing murine and human tumors
Cancer Chemother Pharmacol, 21 (2), 129-33
PubMed 3349560
Publications 1987
-
Mitozolomide (NSC 353451), a new active drug in the treatment of malignant melanoma. Phase II trial in patients with advanced disease
Br J Cancer, 55 (4), 433-5
PubMed 3580266 -
Some procedures to reduce cis-platinum toxicity reduce antitumour activity
Cancer Treat Rev, 14 (3-4), 389-95
PubMed 3326670
Publications 1986
-
Chemosensitivity profiles of human cancers assessed by the 6-day SRC assay on serially xenografted tumors
Int J Cancer, 37 (4), 579-87
PubMed 3957463
Publications 1985
-
Activity of mitozolomide (NSC 353451), a new imidazotetrazine, against xenografts from human melanomas, sarcomas, and lung and colon carcinomas
Cancer Res, 45 (4), 1778-86
PubMed 3978640 -
Characteristics of human tumour xenografts transplanted under the renal capsule of immunocompetent mice
Br J Cancer, 51 (3), 347-56
PubMed 3970811 -
Methodological aspects of the 6-day subrenal capsule assay for measuring the response of human tumors to anticancer agents
Anticancer Res, 5 (4), 329-37
PubMed 4037730 -
The six-day subrenal capsule assay (SRCA) for testing the response of human tumours to anticancer agents. Validity and usefulness in cancer research and treatment
Ann Chir Gynaecol Suppl, 199, 51-9
PubMed 3864392
Publications 1984
-
Phase I study of the plant protein ricin
Cancer Res, 44 (2), 862-5
PubMed 6692385 -
Estrogen receptors and long-term prognosis in breast cancer
Cancer, 53 (11), 2525-9
PubMed 6713348 -
Reduced antineoplastic activity in mice of cisplatin administered with high salt concentration in the vehicle
J Natl Cancer Inst, 73 (3), 743-52
PubMed 6590919 -
Human tumor xenografts transplanted under the renal capsule of conventional mice. Growth rates and host immune response
Int J Cancer, 34 (5), 725-30
PubMed 6500747
Author network for Steinar Aamdal by COREMINE medical
Publications in press
Health-related quality of life in patients with high-risk melanoma randomised in the Nordic phase 3 trial with adjuvant intermediate-dose interferon alfa-2b
Eur J Cancer (in press)
PubMed 22196968
Phase I study of saracatinib (AZD0530) in combination with paclitaxel and/or carboplatin in patients with solid tumours
Br J Cancer (in press)
PubMed 22531637
Publications 2011
Telomerase peptide vaccination in NSCLC: a phase II trial in stage III patients vaccinated after chemoradiotherapy and an 8-year update on a phase I/II trial
Clin Cancer Res, 17 (21), 6847-57
PubMed 21918169
Defining the critical hurdles in cancer immunotherapy
J Transl Med, 9 (1), 214
PubMed 22168571
A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma
J Transl Med, 9, 204
PubMed 22123319
Two different durations of adjuvant therapy with intermediate-dose interferon alfa-2b in patients with high-risk melanoma (Nordic IFN trial): a randomised phase 3 trial
Lancet Oncol, 12 (2), 144-52
PubMed 21256809
Telomerase peptide vaccination combined with temozolomide: a clinical trial in stage IV melanoma patients
Clin Cancer Res, 17 (13), 4568-80
PubMed 21586625
hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes
Cancer Immunol Immunother, 60 (6), 809-18
PubMed 21365467
The preclinical and clinical activity of aviscumine: a potential anticancer drug
Eur J Cancer, 47 (10), 1450-7
PubMed 21482461
Current approaches to adjuvant therapy of melanoma
Eur J Cancer, 47 Suppl 3, S336-7
PubMed 21944005
Publications 2010
SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance
Pharmacogenomics J, 10 (6), 513-23
PubMed 20157331
Human malignant melanoma harbours a large fraction of highly clonogenic cells that do not express markers associated with cancer stem cells
Pigment Cell Melanoma Res, 23 (3), 449-51
PubMed 20236249
Publications 2009
Autoimmune antibodies and recurrence-free interval in melanoma patients treated with adjuvant interferon
J Natl Cancer Inst, 101 (12), 869-77
PubMed 19509353
Intravenous administration of CP-4055 (ELACYT) in patients with solid tumours. A Phase I study
Acta Oncol, 48 (1), 137-45
PubMed 18607882
Assessing quality of life in a randomized clinical trial: correcting for missing data
BMC Med Res Methodol, 9, 28
PubMed 19405936
Publications 2008
Bone marrow micrometastases in advanced stage non-small cell lung carcinoma patients
Lung Cancer, 61 (2), 170-6
PubMed 18261824
S100B in bone marrow aspirates in healthy individuals and malignant melanoma patients
Melanoma Res, 18 (2), 134-40
PubMed 18337650
Population-based prevalence of CDKN2A and CDK4 mutations in patients with multiple primary melanomas
Genes Chromosomes Cancer, 47 (2), 175-84
PubMed 18023021
Publications 2007
Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy
BMC Cancer, 7, 197
PubMed 17956601
The prognostic role of blood lymphocyte subset distribution in patients with resected high-risk primary or regionally metastatic melanoma
J Immunother, 30 (7), 773-9
PubMed 17893569
T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells
Cancer Immunol Immunother, 56 (5), 659-75
PubMed 16947019
Publications 2006
High sensitivity assays for docetaxel and paclitaxel in plasma using solid-phase extraction and high-performance liquid chromatography with UV detection
BMC Clin Pharmacol, 6, 2
PubMed 16412237
Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer
Cancer Immunol Immunother, 55 (12), 1553-64
PubMed 16491401
[Malignant melanoma--diagnosis and treatment]
Tidsskr Nor Laegeforen, 126 (23), 3094-7
PubMed 17160112
Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
Cancer Gene Ther, 13 (10), 905-18
PubMed 16710345
[Retraction of: Diagnostics and treatment of early stages of oral cancer]
Tidsskr Nor Laegeforen, 126 (17), 2287
PubMed 16967079
Publications 2005
Weekly docetaxel with concurrent radiotherapy in locally advanced non-small cell lung cancer: a phase I/II study with 5 years' follow-up
Lung Cancer, 50 (1), 97-105
PubMed 16005105
Preclinical full-scale evaluation of dendritic cells transfected with autologous tumor-mRNA for melanoma vaccination
Cancer Gene Ther, 12 (6), 579-91
PubMed 15818380
Multi-centre Phase II trial of the polyamine synthesis inhibitor SAM486A (CGP48664) in patients with metastatic melanoma
Invest New Drugs, 23 (3), 253-6
PubMed 15868382
Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients
Br J Cancer, 93 (7), 749-56
PubMed 16136047
Phase II study of E7070 in patients with metastatic melanoma
Ann Oncol, 16 (1), 158-61
PubMed 15598954
Second-line chemotherapy in recurrent small cell lung cancer. Results from a crossover schedule after primary treatment with cisplatin and etoposide (EP-regimen) or cyclophosphamide, epirubicin, and vincristin (CEV-regimen)
Lung Cancer, 48 (2), 251-61
PubMed 15829326
Publications 2004
Fotemustine compared with dacarbazine in patients with disseminated malignant melanoma: a phase III study
J Clin Oncol, 22 (6), 1118-25
PubMed 15020614
Development of an optimal sampling strategy for clinical pharmacokinetic studies of the novel anthracycline disaccharide analogue MEN-10755
Cancer Chemother Pharmacol, 54 (1), 64-70
PubMed 15069581
Individualized patient dosing in phase I clinical trials: the role of escalation with overdose control in PNU-214936
J Clin Oncol, 22 (4), 602-9
PubMed 14966084
Immunomagnetic detection and clinical significance of micrometastatic tumor cells in malignant melanoma patients
Clin Cancer Res, 10 (12 Pt 1), 4134-9
PubMed 15217950
Hypofractionated palliative radiotherapy (17 Gy per two fractions) in advanced non-small-cell lung carcinoma is comparable to standard fractionation for symptom control and survival: a national phase III trial
J Clin Oncol, 22 (5), 801-10
PubMed 14990635
Publications 2003
The value of prognostic factors in small cell lung cancer: results from a randomised multicenter study with minimum 5 year follow-up
Lung Cancer, 39 (3), 303-13
PubMed 12609569
Immunisation of metastatic cancer patients with MAGE-3 protein combined with adjuvant SBAS-2: a clinical report
Eur J Cancer, 39 (1), 70-7
PubMed 12504661
Publications 2002
Cisplatin and etoposide regimen is superior to cyclophosphamide, epirubicin, and vincristine regimen in small-cell lung cancer: results from a randomized phase III trial with 5 years' follow-up
J Clin Oncol, 20 (24), 4665-72
PubMed 12488411
Publications 2001
Pharmacokinetics of MEN-10755, a novel anthracycline disaccharide analogue, in two phase I studies in adults with advanced solid tumours
Cancer Chemother Pharmacol, 48 (5), 361-9
PubMed 11761453
Immunobead-based detection and characterization of circulating tumor cells in melanoma patients
Recent Results Cancer Res, 158, 40-50
PubMed 11092032
[Gene therapy in cancer]
Tidsskr Nor Laegeforen, 121 (4), 482-8
PubMed 11255868
[Diagnosis and treatment of oral precancerous lesions]
Tidsskr Nor Laegeforen, 121 (26), 3066-71 (Retracted)
PubMed 11757442
Publications 2000
Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma
J Clin Oncol, 18 (1), 158-66
PubMed 10623706
Carzelesin phase II study in advanced breast, ovarian, colorectal, gastric, head and neck cancer, non-Hodgkin's lymphoma and malignant melanoma: a study of the EORTC early clinical studies group (ECSG)
Cancer Chemother Pharmacol, 46 (2), 167-71
PubMed 10972487
Phase I trial with weekly EO9, a novel bioreductive alkylating indoloquinone, by the EORTC Early Clinical Study Group (ECSG)
Cancer Chemother Pharmacol, 45 (1), 85-8
PubMed 10647507
Publications 1998
Dacarbazine-vindesine versus dacarbazine-vindesine-cisplatin in disseminated malignant melanoma. A randomised phase III trial
Eur J Cancer, 34 (9), 1368-74
PubMed 9849419
Clinical experience of fotemustine, cisplatin and high dose tamoxifen in patients with metastatic malignant melanoma
Melanoma Res, 8 (6), 565-72
PubMed 9918419
Zilascorb(H-2), a low-toxicity protein synthesis inhibitor that exhibits signs of anticancer activity in malignant melanoma
Anti-Cancer Drugs, 9 (9), 797-802
Zilascorb(2H), a low-toxicity protein synthesis inhibitor that exhibits signs of anticancer activity in malignant melanoma
Anticancer Drugs, 9 (9), 797-802
PubMed 9840726
Capillary protein leak syndrome appears to explain fluid retention in cancer patients who receive docetaxel treatment
J Clin Oncol, 16 (10), 3426-32
PubMed 9779722
Publications 1997
Zilascorb(H-2), a new reversible protein synthesis inhibitor: Clinical study of an oral preparation
Anti-Cancer Drugs, 8 (3), 296-303
Zilascorb(2H), a new reversible protein synthesis inhibitor: clinical study of an oral preparation
Anticancer Drugs, 8 (3), 296-303
PubMed 9095337
Zeniplatin in advanced malignant melanoma and renal cancer: phase II studies with unexpected nephrotoxicity
Cancer Chemother Pharmacol, 40 (5), 439-43
PubMed 9272122
Publications 1996
Phase II clinical trials with rhizoxin in breast cancer and melanoma. The EORTC Early Clinical Trials Group
Br J Cancer, 73 (3), 397-9
PubMed 8562349
Correlation of DNA ploidy and S-phase fraction with chemotherapeutic response and survival in a randomized study of disseminated malignant melanoma
Int J Cancer, 65 (1), 1-5
PubMed 8543385
Phase I pharmacokinetics and limited sampling strategies for the bioreductive alkylating drug EO9. EORTC Early Clinical Trials Group
Eur J Cancer, 32A (9), 1518-22
PubMed 8911111
Multicentre phase II pharmacological evaluation of rhizoxin. Eortc early clinical studies (ECSG)/pharmacology and molecular mechanisms (PAMM) groups
Br J Cancer, 74 (12), 1944-8
PubMed 8980394
Transcapillary forces of the subcutaneous tissue in patients treated with interleukin-2 and alpha-interferon: no capillary protein leak syndrome?
J Exp Ther Oncol, 1 (3), 155-61
PubMed 9414399
Publications 1995
Serum levels of cytokines and soluble cytokine receptors in patients with metastatic renal cell carcinoma or malignant melanoma receiving IL-2/interferon-alpha combination therapy
Acta Oncol, 34 (5), 599-603
PubMed 7546824
Phase II studies of docetaxel in the treatment of various solid tumours. EORTC Early Clinical Trials Group and the EORTC Soft Tissue and Bone Sarcoma Group
Eur J Cancer, 31A Suppl 4, S21-4
PubMed 7577101
Publications 1994
Gemcitabine in patients with advanced malignant melanoma or gastric cancer: phase II studies of the EORTC Early Clinical Trials Group
Ann Oncol, 5 (5), 471-2
PubMed 8075055
Clinical studies with EO9, a new indoloquinone bioreductive alkylating cytotoxic agent. EORTC Early Clinical Trials Group
Oncol Res, 6 (10-11), 519-23
PubMed 7620220
Docetaxel (Taxotere) in advanced malignant melanoma: a phase II study of the EORTC Early Clinical Trials Group
Eur J Cancer, 30A (8), 1061-4
PubMed 7654429
Publications 1993
Activity and unexpected lung toxicity of the sequential administration of two alkylating agents--dacarbazine and fotemustine--in patients with melanoma
Eur J Cancer, 29A (5), 711-9
PubMed 8471329
A double blind study to evaluate the tolerability of gadodiamide injection and its effect on renal function in patients undergoing cerebral magnetic resonance imaging
Br J Radiol, 66 (790), 871-6
PubMed 8220968
Publications 1992
Detection of bone marrow metastases in small cell lung cancer patients. Comparison of immunologic and morphologic methods
Am J Pathol, 141 (3), 531-8
PubMed 1381558
Levels of nm23 messenger RNA in metastatic malignant melanomas: inverse correlation to disease progression
Cancer Res, 52 (21), 6088-91
PubMed 1356624
Neuron-specific enolase as a prognostic factor in metastatic malignant melanoma
Eur J Cancer, 28A (10), 1692-5
PubMed 1389487
Can ondansetron hydrochloride (Zofran) enhance the nephrotoxic potential of other drugs?
Ann Oncol, 3 (9), 774
PubMed 1450070
Sequential administration of dacarbazine and fotemustine in patients with disseminated malignant melanoma--an effective combination with unexpected toxicity
Eur J Cancer, 28 (2-3), 447-50
PubMed 1591062
Publications 1991
Selection of anti-SCLC antibodies for diagnosis of bone marrow metastasis
Br J Cancer Suppl, 14, 49-53
PubMed 1645572
Sequential administration of recombinant human interleukin-2 and dacarbazine in metastatic melanoma: a multicenter phase II study
J Clin Oncol, 9 (9), 1687-91
PubMed 1875225
Publications 1990
Studies of the L-myc DNA polymorphism and relation to metastasis in Norwegian lung cancer patients
Br J Cancer, 61 (6), 809-12
PubMed 1973618
Neuron specific enolase (NSE) in serum of patients with malignant melanoma
Cancer Lett, 52 (1), 29-31
PubMed 2354416
Publications 1989
Sequential administration of recombinant human interleukin-2 and dacarbazine in metastatic melanoma. A multicentre phase II study
Eur J Cancer Clin Oncol, 25 Suppl 3, S41-3
PubMed 2697578
Publications 1988
Extrapulmonary, tissue-specific metastasis formation in nude mice injected with FEMX-I human melanoma cells
Cancer Res, 48 (15), 4382-8
PubMed 3390834
A new experimental metastasis model in athymic nude mice, the human malignant melanoma LOX
Int J Cancer, 41 (3), 442-9
PubMed 3346110
Sodium thiosulfate fails to increase the therapeutic index of intravenously administered cis-diamminedichloroplatinum (II) in mice bearing murine and human tumors
Cancer Chemother Pharmacol, 21 (2), 129-33
PubMed 3349560
Publications 1987
Mitozolomide (NSC 353451), a new active drug in the treatment of malignant melanoma. Phase II trial in patients with advanced disease
Br J Cancer, 55 (4), 433-5
PubMed 3580266
Some procedures to reduce cis-platinum toxicity reduce antitumour activity
Cancer Treat Rev, 14 (3-4), 389-95
PubMed 3326670
Publications 1986
Chemosensitivity profiles of human cancers assessed by the 6-day SRC assay on serially xenografted tumors
Int J Cancer, 37 (4), 579-87
PubMed 3957463
Publications 1985
Activity of mitozolomide (NSC 353451), a new imidazotetrazine, against xenografts from human melanomas, sarcomas, and lung and colon carcinomas
Cancer Res, 45 (4), 1778-86
PubMed 3978640
Characteristics of human tumour xenografts transplanted under the renal capsule of immunocompetent mice
Br J Cancer, 51 (3), 347-56
PubMed 3970811
Methodological aspects of the 6-day subrenal capsule assay for measuring the response of human tumors to anticancer agents
Anticancer Res, 5 (4), 329-37
PubMed 4037730
The six-day subrenal capsule assay (SRCA) for testing the response of human tumours to anticancer agents. Validity and usefulness in cancer research and treatment
Ann Chir Gynaecol Suppl, 199, 51-9
PubMed 3864392
Publications 1984
Phase I study of the plant protein ricin
Cancer Res, 44 (2), 862-5
PubMed 6692385
Estrogen receptors and long-term prognosis in breast cancer
Cancer, 53 (11), 2525-9
PubMed 6713348
Reduced antineoplastic activity in mice of cisplatin administered with high salt concentration in the vehicle
J Natl Cancer Inst, 73 (3), 743-52
PubMed 6590919
Human tumor xenografts transplanted under the renal capsule of conventional mice. Growth rates and host immune response
Int J Cancer, 34 (5), 725-30
PubMed 6500747




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