
| Gunnar Kvalheim | |
| Position: | MD |
| Phone: | +47 22 93 59 13 |
| Email: | |
Author network for Gunnar Kvalheim by COREMINE medical
Publications in press
Ultra-short course sirolimus contributes to effective GVHD prophylaxis after reduced-intensity allogeneic hematopoietic cell transplantation
Bone Marrow Transplant (in press)
PubMed 22522568
Synergistic effect of SCF and G-CSF on stem-like properties in prostate cancer cell lines
Tumour Biol (in press)
PubMed 22252524
Publications 2011
Transiently redirected T cells for adoptive transfer
Cytotherapy, 13 (5), 629-40
PubMed 21174490
High dose chemotherapy with autologous stem cell support for patients with histologically transformed B-cell non-Hodgkin lymphomas. A Norwegian multi centre phase II study
Br J Haematol, 152 (5), 600-10
PubMed 21241276
The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation
Adv Pharmacol Sci, 2011, 157015
PubMed 21912538
Priming with r-metHuSCF and filgrastim or chemotherapy and filgrastim in patients with malignant lymphomas: a randomized phase II pilot study of mobilization and engraftment
Bone Marrow Transplant, 46 (1), 44-51
PubMed 20436517
Side population cells in highly enriched CD34-positive cells from peripheral blood progenitor cells identify an immature subtype of hematopoietic progenitor cells but do not predict time to engraftment in patients treated with high-dose therapy
Eur J Haematol, 87 (6), 494-502
PubMed 21752097
Prostate cancer cell lines under hypoxia exhibit greater stem-like properties
PLoS One, 6 (12), e29170
PubMed 22216200
The role of plerixafor in optimizing peripheral blood stem cell mobilization for autologous stem cell transplantation
Leukemia, 25 (1), 1-6
PubMed 21224858
hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes
Cancer Immunol Immunother, 60 (6), 809-18
PubMed 21365467
Ameloblastin expression and putative autoregulation in mesenchymal cells suggest a role in early bone formation and repair
Bone, 48 (2), 406-13
PubMed 20854943
The mild inflammatory response in febrile neutropenic lymphoma patients with low risk of complications is more pronounced in patients receiving tobramycin once daily compared with three times daily
Scand J Immunol, 74 (6), 632-9
PubMed 21883353
Mycoplasma contamination revisited: mesenchymal stromal cells harboring Mycoplasma hyorhinis potently inhibit lymphocyte proliferation in vitro
PLoS One, 6 (1), e16005
PubMed 21264307
Publications 2010
Mobilization strategies in hard-to-mobilize patients with lymphoid malignancies
Eur J Haematol, 85 (6), 463-71
PubMed 20738393
Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer (vol 1, pg 160, 2007)
Mol. Oncol., 4 (2), 169
Ex vivo expansion protocol for human tumor specific T cells for adoptive T cell therapy
J Immunol Methods, 355 (1-2), 52-60
PubMed 20171968
Ameloblastin promotes bone growth by enhancing proliferation of progenitor cells and by stimulating immunoregulators
Eur J Oral Sci, 118 (5), 451-9
PubMed 20831578
Publications 2009
Immunomagnetic detection of micrometastatic cells in bone marrow in uveal melanoma patients
Acta Ophthalmol, 87 (8), 830-6
PubMed 19055657
Identification of cancer stem-like side population cells in ovarian cancer cell line OVCAR-3
Ultrastruct Pathol, 33 (4), 175-81
PubMed 19728235
Induction of circadian rhythm in cultured human mesenchymal stem cells by serum shock and cAMP analogs in vitro
Chronobiol Int, 26 (2), 242-57
PubMed 19212839
Publications 2008
Experimental attempt to produce mRNA transfected dendritic cells derived from enriched CD34+blood progenitor cells
Cent. Eur. J. Med., 3 (1), 21-28
Publications 2007
Impact of disseminated tumor cells in bone marrow at diagnosis in patients with nonmetastatic prostate cancer treated by definitive radiotherapy
Int J Cancer, 120 (8), 1603-9
PubMed 17230512
A full scale comparative study of methods for generation of functional Dendritic cells for use as cancer vaccines
BMC Cancer, 7, 119
PubMed 17608923
mRNA transfection of DC in the immature or mature state: comparable in vitro priming of Th and cytotoxic T lymphocytes against DC electroporated with tumor cell line-derived mRNA
Cytotherapy, 9 (6), 587-92
PubMed 17882723
T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells
Cancer Immunol Immunother, 56 (5), 659-75
PubMed 16947019
Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer
Mol Oncol, 1 (2), 160-71
PubMed 19383292
Publications 2006
Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer
Cancer Immunol Immunother, 55 (12), 1553-64
PubMed 16491401
The mitogen-activated protein kinases (MAPK) p38 and JNK are markers of tumor progression in breast carcinoma
Gynecol Oncol, 102 (3), 453-61
PubMed 16494928
Monitoring of disseminated tumor cells in bone marrow in high-risk breast cancer patients treated with high-dose chemotherapy
Int J Cancer, 118 (11), 2877-81
PubMed 16381016
Standardization of cell analysis methods in clinical cellular therapy programs: A challenge for ISCT
Cytotherapy, 8 (6), 528-9
PubMed 17148028
Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
Cancer Gene Ther, 13 (10), 905-18
PubMed 16710345
Growth factor receptors in hematopoietic stem cells: EPH family expression in CD34+ and CD133+ cell populations from mobilized peripheral blood
Int J Immunopathol Pharmacol, 19 (1), 49-56
PubMed 16569339
Comparison of the clinical significance of occult tumor cells in blood and bone marrow in breast cancer
Int J Cancer, 118 (8), 2013-9
PubMed 16287086
Publications 2005
Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma
Cancer, 103 (8), 1631-43
PubMed 15742334
Angiogenic molecule expression is downregulated in effusions from breast cancer patients
Breast Cancer Res Treat, 94 (1), 71-80
PubMed 16142438
Stem cell therapy still not here
Cytotherapy, 7 (5), 456-7
PubMed 16236635
Preclinical full-scale evaluation of dendritic cells transfected with autologous tumor-mRNA for melanoma vaccination
Cancer Gene Ther, 12 (6), 579-91
PubMed 15818380
Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients
Br J Cancer, 93 (7), 749-56
PubMed 16136047
Publications 2004
Infused CD34 cell dose, but not tumour cell content of peripheral blood progenitor cell grafts, predicts clinical outcome in patients with diffuse large B-cell lymphoma and follicular lymphoma grade 3 treated with high-dose therapy
Br J Haematol, 125 (5), 605-12
PubMed 15147376
Experimental attempt to introduce a vaccine therapy by using DC-developed from CD34+cells
NATO SCI SER I LIFE, 361, 134
Development of a clinical grade procedure for generation of mRNA transfected dendritic cells from purified frozen CD34(+) blood progenitor cells
Int J Immunopathol Pharmacol, 17 (3), 255-63
PubMed 15461859
The prognostic value of isolated tumor cells in bone marrow in breast cancer patients: evaluation of morphological categories and the number of clinically significant cells
Clin Cancer Res, 10 (9), 3091-7
PubMed 15131048
Treatment of Burkitt's/Burkitt-like lymphoma in adolescents and adults: a 20-year experience from the Norwegian Radium Hospital with the use of three successive regimens
Ann Oncol, 15 (7), 1072-8
PubMed 15205201
Isolated tumor cells in bone marrow three years after diagnosis in disease-free breast cancer patients predict unfavorable clinical outcome
Clin Cancer Res, 10 (16), 5342-8
PubMed 15328170
Mathematical modeling of granulocyte reconstitution after high-dose chemotherapy with stem cell support: effect of post-transplant G-CSF treatment
J Theor Biol, 231 (1), 69-83
PubMed 15363930
Publications 2003
JACIE accreditation in Europe moves ahead
Cytotherapy, 5 (4), 306-8
PubMed 12944236
The prognostic impact of cytokeratin-positive cells in bone marrow of patients with localized prostate cancer
Int J Cancer, 103 (1), 91-6
PubMed 12455058
A protocol for generation of clinical grade mRNA-transfected monocyte-derived dendritic cells for cancer vaccines
Scand J Immunol, 58 (5), 578-86
PubMed 14629630
Old and new research into micrometastases in prostate cancer
Scand. J. Urol. Nephrol., 37 212, 37-39
Old and new research into micrometastases in prostate cancer
Scand J Urol Nephrol Suppl (212), 37-9
PubMed 12841326
High-dose therapy improves progression-free survival and survival in relapsed follicular non-Hodgkin's lymphoma: results from the randomized European CUP trial
J Clin Oncol, 21 (21), 3918-27
PubMed 14517188
A survey of therapeutic hemapheresis in Norway year 2000
Transfus Apher Sci, 28 (2), 135-41
PubMed 12679117
[Therapeutic hemapheresis]
Tidsskr Nor Laegeforen, 123 (17), 2439-42
PubMed 14594145
Detection of isolated tumor cells in bone marrow is an independent prognostic factor in breast cancer
J Clin Oncol, 21 (18), 3469-78
PubMed 12972522
A mathematical model for reconstitution of granulopoiesis after high dose chemotherapy with autologous stem cell transplantation
J Math Biol, 47 (2), 101-36
PubMed 12883857
Publications 2001
Combination chemotherapy containing mitoguazone, ifosfamide, methotrexate, etoposide (MIME) and G-CSF efficiently mobilize peripheral blood progenitor cells in heavily pre-treated relapsed lymphoma patients
Eur. J. Haematol., 66 64, 14-20
Combination chemotherapy containing mitoguazone, ifosfamide, methotrexate, etoposide (MIME) and G-CSF efficiently mobilize peripheral blood progenitor cells in heavily pre-treated relapsed lymphoma patients
Eur J Haematol Suppl, 64, 14-20
PubMed 11486395
High-dose therapy with autologous stem cell transplantation in patients with peripheral T cell lymphomas
Bone Marrow Transplant, 27 (7), 711-6
PubMed 11360110
High-dose therapy in patients with Hodgkin's disease: the use of selected CD34(+) cells is as safe as unmanipulated peripheral blood progenitor cells
Bone Marrow Transplant, 28 (9), 849-57
PubMed 11781645
CD34(+) cell enrichment depletes atypical CD30(+) cells from PBPC grafts in patients with HD
Cytotherapy, 3 (4), 295-305
PubMed 12171718
Effects of dose-intensive chemotherapy and radiotherapy on serum n-terminal proatrial natriuretic peptide in high-risk breast cancer patients
Breast Cancer Res Treat, 67 (3), 235-44
PubMed 11561769
Regulatory aspects and accreditation of the clinical use of hematopoietic progenitor cells in Europe
J Biol Regul Homeost Agents, 15 (1), 79-80
PubMed 11388748
Detection of isolated tumor cells in bone marrow in early-stage breast carcinoma patients: comparison with preoperative clinical parameters and primary tumor characteristics
Clin Cancer Res, 7 (12), 4122-9
PubMed 11751511
Publications 2000
Demonstration of highly specific toxicity of the alpha-emitting radioimmunoconjugate(211)At-rituximab against non-Hodgkin's lymphoma cells
Br J Cancer, 83 (10), 1375-9
PubMed 11044364
Publications 1999
High-dose therapy supported with immunomagnetic purged autologous bone marrow in high-grade B cell non-Hodgkin's lymphoma
Bone Marrow Transplant, 24 (8), 865-72
PubMed 10516698
Standardization of the immunocytochemical detection of cancer cells in BM and blood: I. establishment of objective criteria for the evaluation of immunostained cells
Cytotherapy, 1 (5), 377-88
PubMed 20426539
ESTIC position paper: high-dose chemotherapy for breast cancer, investigation should continue
Ann Oncol, 10 (8), 903-5
PubMed 10509150
Detection of cancer cells in effusions from patients diagnosed with gynaecological malignancies. Evaluation of five epithelial markers
Virchows Arch, 435 (1), 43-9
PubMed 10431845
EBMT and ISHAGE-Europe create a foundation for inspection and accreditation in Europe
Cytotherapy, 1 (5), 363-4
PubMed 20426536
Minimal residual disease in breast cancer
Cancer Metastasis Rev, 18 (1), 101-8
PubMed 10505549
FEC mobilized stem cells for high-dose therapy in breast cancer patients. SB6 9401 Study Group
Acta Oncol, 38 (2), 239-45
PubMed 10227447
Persistent changes in the immune system 4-10 years after ABMT
Bone Marrow Transplant, 24 (8), 873-8
PubMed 10516699
European survey of the flow cytometric determination of CD34-expressing cells
Cytotherapy, 1 (4), 343-7
PubMed 20426564
Publications 1998
Combination chemotherapy with mitoguazon, ifosfamide, MTX, etoposide (MIME) and G-CSF can efficiently mobilize PBPC in patients with Hodgkin's and non-Hodgkin's lymphoma
Bone Marrow Transplant, 21 (9), 873-8
PubMed 9613778
Immunocytochemical detection of isolated epithelial cells in bone marrow: non-specific staining and contribution by plasma cells directly reactive to alkaline phosphatase
J Pathol, 185 (4), 427-34
PubMed 9828843
Diagnosis of minimal residual disease in bone marrow and blood in cancer patients--methods and clinical implications
Acta Oncol, 37 (5), 455-62
PubMed 9831374
Detection and quantification of residual disease in bone marrow and PBPC
EUROCANCER 98, 19-21
Increased sensitivity for detection of micrometastases in bone-marrow/peripheral-blood stem-cell products from breast-cancer patients by negative immunomagnetic separation
Int J Cancer, 78 (5), 556-60
PubMed 9808522
Mycobacterial crossreactivity of M. tuberculosis reactive T cell clones from naturally converted PPD positive healthy subjects
FEMS Immunol Med Microbiol, 20 (3), 231-8
PubMed 9566494
Publications 1997
Immunomagnetic techniques for the enrichment and detection of isolated breast carcinoma cells in bone marrow and peripheral blood
J Hematother, 6 (2), 103-14
PubMed 9131439
Publications 1996
Residual leukemia and immunomagnetic bead purging in patients with BCR-ABL-positive acute lymphoblastic leukemia
Bone Marrow Transplant, 18 (3), 541-8
PubMed 8879615
[High-dose therapy with autologous stem cell support in malignant lymphoma and breast cancer. Experiences with hematopoietic stem cells isolate from blood]
Tidsskr Nor Laegeforen, 116 (21), 2547-51
PubMed 8928122
Leucocyte depletion filter removes cancer cells in human blood
Acta Anaesthesiol Scand, 40 (1), 118-20
PubMed 8904269
Purging of autografts: methods and clinical significance
Ann Med, 28 (2), 167-73
PubMed 8732646
Detection of occult tumour cells in bone marrow and blood in breast cancer patients--methods and clinical significance
Acta Oncol, 35 Suppl 8, 13-8
PubMed 9073044
Immunomagnetic purging of lymphoma cells from autografts
J Hematother, 5 (5), 561-2
PubMed 8938530
[High-dose therapy of cancer with CD34 positive cells as stem cell support]
Tidsskr Nor Laegeforen, 116 (21), 2542-6
PubMed 8928121
Purging of tumor cells from leukapheresis products: experimental and clinical aspects
J Hematother, 5 (4), 427-36
PubMed 8877718
Publications 1995
Semiquantitative polymerase chain reaction for t(14;18) in follicular lymphomas: a colorimetric approach
Lab Invest, 72 (4), 411-8
PubMed 7723279
Granulocyte colony-stimulating factor improves myelopoiesis and host defense in fulminant intra-abdominal sepsis in rats
Shock, 4 (1), 68-73
PubMed 7552781
An Effective, Direct Immunomagnetic Procedure for Purging Acute Lymphoblastic Leukemia Cells from Human Bone Marrow
Pathol Oncol Res, 1 (1), 32-37
PubMed 11173565
Publications 1994
[High-dose autologous stem cell support in malignant diseases--an established method, uncertain indication]
Tidsskr Nor Laegeforen, 114 (19), 2240-1
PubMed 7992286
Autologous bone marrow transplantation of non-Hodgkin's lymphoma patients with marrow purged using immunomagnetic beads
Prog Clin Biol Res, 389, 133-8
PubMed 7700895
All-trans retinoic acid directly inhibits granulocyte colony-stimulating factor-induced proliferation of CD34+ human hematopoietic progenitor cells
Blood, 84 (9), 2940-5
PubMed 7524761
A direct and effective immunomagnetic method for bone marrow purging in non-T ALL malignancies. The use of an anti-HLA-DR antibody gives sustained engraftment
Prog Clin Biol Res, 389, 119-24
PubMed 7700893
Publications 1993
Homocysteine and other thiols in plasma and urine: automated determination and sample stability
Clin Chem, 39 (2), 263-71
PubMed 8432015
Publications 1992
Recurrent venous thrombosis during warfarin treatment related to acquired protein S deficiency
Thromb Res, 66 (6), 729-34
PubMed 1519231
Successful autologous transplantation of immunomagnetic bead purged bone marrow in non-Hodgkin's lymphoma
Prog Clin Biol Res, 377, 189-95
PubMed 1438415
[Infection problems in the leukopenia phase after autologous bone marrow transplantation]
Tidsskr Nor Laegeforen, 112 (13), 1723-6
PubMed 1509434
EFFECTIVE ISOLATION OF HUMAN HEMATOPOIETIC PROGENITOR CELLS - A NEW METHOD FOR DETACHMENT OF IMMUNOMAGNETIC BEADS FROM POSITIVELY SELECTED CD34+ CELLS
INT J CELL CLONING, 10 1, 108-110
Isolation and characterization of human hematopoietic progenitor cells: an effective method for positive selection of CD34+ cells
Leukemia, 6 (8), 845-52
PubMed 1379314
Polymerase chain reaction monitoring shows a high efficacy of clinical immunomagnetic purging in patients with centroblastic-centrocytic non-Hodgkin's lymphoma
Blood, 80 (10), 2688-90
PubMed 1421385
An effective immunomagnetic method for bone marrow purging in T cell malignancies
Bone Marrow Transplant, 9 (5), 319-23
PubMed 1617315
Publications 1991
Autologous transplantation of an immunomagnetic bead purged marrow in patients with relapsed acute lymphoblastic leukemia
Haematologica, 76 Suppl 1, 29-36
PubMed 1650742
Publications 1990
[Autologous bone marrow transplantation in children--experience with neuroblastoma]
Tidsskr Nor Laegeforen, 110 (19), 2513-6
PubMed 2219008
Publications 1989
Immunomagnetic removal of B-lymphoma cells using a novel mono-sized magnetizable polymer bead, M-280, in conjunction with primary IgM and IgG antibodies
Bone Marrow Transplant, 4 (5), 567-74
PubMed 2790334
Publications 1988
New indirect approach to the therapeutic use of immunotoxins
J Natl Cancer Inst, 80 (6), 439-43
PubMed 3259265
IMMUNOMAGNETIC PURGING OF BETA-LYMPHOMA CELLS FROM BONE-MARROW
Bone Marrow Transplant., 3 1, 97
Successful clinical use of an anti-HLA-DR monoclonal antibody for autologous bone marrow transplantation
J Natl Cancer Inst, 80 (16), 1322-5
PubMed 3050139
Immunomagnetic removal of B-lymphoma cells from human bone marrow: a procedure for clinical use
Bone Marrow Transplant, 3 (1), 31-41
PubMed 3048468
Epitopes of the Mycobacterium tuberculosis 65-kilodalton protein antigen as recognized by human T cells
J Immunol, 141 (8), 2749-54
PubMed 2459228
Survival of breast cancer patients diagnosed during pregnancy or lactation
Br J Cancer, 58 (3), 382-4
PubMed 3179191
Publications 1987
ANTIBODY-MEDIATED METHODS - ALLOGRAFTS AND AUTOGRAFTS - DISCUSSION
Bone Marrow Transplant., 2 2, 99-103
Removal of cells from a malignant B-cell line from bone marrow with immunomagnetic beads and with complement and immunoglobulin switch variant mediated cytolysis
Leuk Res, 11 (12), 1119-25
PubMed 3320581
Elimination of B-lymphoma cells from human bone marrow: model experiments using monodisperse magnetic particles coated with primary monoclonal antibodies
Cancer Res, 47 (3), 846-51
PubMed 3492268
ANTIGEN-BINDING PROPERTIES OF ANTIBODIES COATED ON MAGNETIC POLYMER BEADS
Bone Marrow Transplant., 2 2, 81-83
IMMUNOMAGNETIC TREATMENT OF BONE-MARROW ALLOGRAFTS
Bone Marrow Transplant., 2 2, 94-98
Depletion of T lymphocytes from human bone marrow. Use of magnetic monosized polymer microspheres coated with T-lymphocyte-specific monoclonal antibodies
Transplantation, 43 (3), 366-71
PubMed 3103274
Publications 1986
Mycobacterium bovis BCG-induced human T-cell clones from BCG-vaccinated healthy subjects: antigen specificity and lymphokine production
Infect Immun, 53 (3), 491-7
PubMed 2427449
Publications 1985
Intra-arterial infusion of mitomycin C in treatment of breast cancer: occurrence of skin necrosis in irradiated patients
Radiother Oncol, 4 (2), 127-32
PubMed 3934716
Determination of warfarin in human plasma by high performance liquid chromatography and photodiode array detector
Ther Drug Monit, 7 (3), 329-35
PubMed 4049474
Publications 1984
Phase I study of the plant protein ricin
Cancer Res, 44 (2), 862-5
PubMed 6692385




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