
| Svend Aakhus | |
| Position: | Consultant Cardiologist |
| Phone: | +47 23 07 24 09 |
| Email: | |
PhD research fellows supervison: Ketil Lunde, Jan Otto Beitnes, Marit Aarønæs, Kaspar Broch, Vibeke Marie Almaas, Kari Nytrøen, Mette Elise Estensen, Lene Anette Rustad, Hanne Aulie, Monika Bednarz, Jo Eidet, Amjad Hussain, Gabor Kunszt, Klaus Murbraech, Jon Christiansen
International collaboration: University of Ghent, University Hospital Bern, University Hospital Leuven, University Hospital Copenhagen
Research topics: Left ventricular function, valvular function, stem cells in cardiology. Echocardiography.
Professional background: Specialist in Internal Medicine and Cardiology. Chief of Section, Section of Cardiac Ultrasound, Department of Cardiology. Professor in Cardiology, NTNU.
Main focus:
Clinical cardiology, echocardiography, noninvasive techniques
Main methods:
Echocardiography
Author network for Svend Aakhus by COREMINE medical
Publications in press
Peak oxygen uptake during cardiopulmonary exercise testing determines response to cardiac resynchronization therapy
J Cardiol (in press)
PubMed 22542140
Intramyocardial injections of human mesenchymal stem cells following acute myocardial infarction modulate scar formation and improve left ventricular function
Cell Transplant (in press)
PubMed 22410280
High-sensitive troponin T and N-terminal-brain-natriuretic-peptide predict outcome in symptomatic aortic stenosis
Scand Cardiovasc J (in press)
PubMed 22545649
The influence of intracoronary injection of bone marrow cells on prothrombotic markers in patients with acute myocardial infarction
Thromb Res (in press)
PubMed 22192151
Activin A and cardiovascular disease in type 2 diabetes mellitus
Diab Vasc Dis Res (in press)
PubMed 22234949
Publications 2012
Systemic arterial response and ventriculo-arterial interaction during normal pregnancy
Am J Hypertens, 25 (6), 672-7
PubMed 22460202
Publications 2011
Left ventricular systolic and diastolic function improve after acute myocardial infarction treated with acute percutaneous coronary intervention, but are not influenced by intracoronary injection of autologous mononuclear bone marrow cells: a 3 year serial echocardiographic sub-study of the randomized-controlled ASTAMI study
Eur J Echocardiogr, 12 (2), 98-106
PubMed 20851818
Stem cells for cardiac repair in acute myocardial infarction
Expert Rev Cardiovasc Ther, 9 (8), 1015-25
PubMed 21878046
Postsystolic shortening is a strong predictor of recovery of systolic function in patients with non-ST-elevation myocardial infarction
Eur J Echocardiogr, 12 (7), 483-9
PubMed 21609975
Evaluation of right ventricular dysfunction by myocardial strain echocardiography in patients with intestinal carcinoid disease
J Am Soc Echocardiogr, 24 (6), 644-50
PubMed 21440415
Regional myocardial function after intracoronary bone marrow cell injection in reperfused anterior wall infarction - a cardiovascular magnetic resonance tagging study
J Cardiovasc Magn Reson, 13, 22
PubMed 21414223
Long-term outcome of percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy: a Scandinavian multicenter study
Circ Cardiovasc Interv, 4 (3), 256-65
PubMed 21540441
Assessment of left ventricular function in ST-elevation myocardial infarction by global longitudinal strain: a comparison with ejection fraction, infarct size, and wall motion score index measured by non-invasive imaging modalities
Eur J Echocardiogr, 12 (9), 678-83
PubMed 21810829
[A man in his 60s with severe respiratory failure]
Tidsskr Nor Laegeforen, 131 (17), 1654-7
PubMed 21901039
Galectin-3 in heart failure: high levels are associated with all-cause mortality
Int J Cardiol, 150 (3), 361-4
PubMed 21641051
Osteoprotegerin levels predict mortality in patients with symptomatic aortic stenosis
J Intern Med, 270 (5), 452-60
PubMed 21623962
Circulating levels of non-phosphorylated undercarboxylated matrix Gla protein are associated with disease severity in patients with chronic heart failure
Clin Sci (Lond), 121 (3), 119-27
PubMed 21294711
Prognostic value of cardiac troponin T in patients with moderate to severe heart failure scheduled for cardiac resynchronization therapy
Am Heart J, 161 (6), 1031-7
PubMed 21641347
Publications 2010
Activin A in carcinoid heart disease: a possible role in diagnosis and pathogenesis
Neuroendocrinology, 92 (3), 168-77
PubMed 20720391
Plasma CCN2/connective tissue growth factor is associated with right ventricular dysfunction in patients with neuroendocrine tumors
BMC Cancer, 10, 6
PubMed 20053285
Strain echocardiography and wall motion score index predicts final infarct size in patients with non-ST-segment-elevation myocardial infarction
Circ Cardiovasc Imaging, 3 (2), 187-94
PubMed 20075142
Strain echocardiography predicts acute coronary occlusion in patients with non-ST-segment elevation acute coronary syndrome
Eur J Echocardiogr, 11 (6), 501-8
PubMed 20185525
Changes of myocardial function in patients with non-ST-elevation acute coronary syndrome awaiting coronary angiography
Am J Cardiol, 105 (9), 1212-8
PubMed 20403468
Cell treatment after acute myocardial infarction prevents early decline in circulating IGF-1
Scand Cardiovasc J, 44 (5), 267-72
PubMed 21080844
Recommendations for the practice of echocardiography in infective endocarditis
Eur J Echocardiogr, 11 (2), 202-19
PubMed 20223755
Determinants and prognostic implications of cardiac troponin T measured by a sensitive assay in type 2 diabetes mellitus
Cardiovasc Diabetol, 9, 52
PubMed 20843304
Frequency of left ventricular thrombus in patients with anterior wall acute myocardial infarction treated with percutaneous coronary intervention and dual antiplatelet therapy
Am J Cardiol, 106 (9), 1197-200
PubMed 21029812
Undercarboxylated matrix Gla protein is associated with indices of heart failure and mortality in symptomatic aortic stenosis
J Intern Med, 268 (5), 483-92
PubMed 20804515
Assessment of response criteria to cardiac resynchronization therapy (CRT) and prediction of response
Scand Cardiovasc J, 44 (6), 337-45
PubMed 21080864
Publications 2009
Long-term results after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: the ASTAMI randomised, controlled study
Heart, 95 (24), 1983-9
PubMed 19833610
[Heart disease with a rare cause]
Tidsskr Nor Laegeforen, 129 (3), 191
PubMed 19192507
[A patient with aortic stenosis and reduced left ventricular function]
Tidsskr Nor Laegeforen, 129 (20), 2119-21
PubMed 19855451
Increased production of CXCL16 in experimental and clinical heart failure: a possible role in extracellular matrix remodeling
Circ Heart Fail, 2 (6), 624-32
PubMed 19919988
Publications 2008
Noninvasive separation of large, medium, and small myocardial infarcts in survivors of reperfused ST-elevation myocardial infarction: a comprehensive tissue Doppler and speckle-tracking echocardiography study
Circ Cardiovasc Imaging, 1 (3), 189-96, 2 p following 196
PubMed 19808542
Heart rate adjustments and analysis of recovery patterns of ST-segment depression in type 2 diabetes
Int J Cardiol, 127 (1), 129-32
PubMed 17532067
[Musculoskeletal pain in ultrasound operators]
Tidsskr Nor Laegeforen, 128 (23), 2701-5
PubMed 19079414
Anterior myocardial infarction with acute percutaneous coronary intervention and intracoronary injection of autologous mononuclear bone marrow cells: safety, clinical outcome, and serial changes in left ventricular function during 12-months' follow-up
J Am Coll Cardiol, 51 (6), 674-6
PubMed 18261689
Intracoronary injection of mononuclear bone marrow cells after acute myocardial infarction: lessons from the ASTAMI trial
Eur. Heart J. Suppl., 10 (K), K35-K38
Cell therapy in acute myocardial infarction: measures of efficacy
Heart, 94 (8), 969-70
PubMed 18625788
Inflammatory responses after intracoronary injection of autologous mononuclear bone marrow cells in patients with acute myocardial infarction
Am Heart J, 155 (1), 55.e1-9
PubMed 18082489
Publications 2007
Cell therapy in myocardial infarction
Lancet, 369 (9580), 2142-3
PubMed 17604783
Global longitudinal strain measured by two-dimensional speckle tracking echocardiography is closely related to myocardial infarct size in chronic ischaemic heart disease
Clin Sci (Lond), 113 (6), 287-96
PubMed 17501720
Exercise capacity and quality of life after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: results from the Autologous Stem cell Transplantation in Acute Myocardial Infarction (ASTAMI) randomized controlled trial
Am Heart J, 154 (4), 710.e1-8
PubMed 17892996
Publications 2006
Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction
N Engl J Med, 355 (12), 1199-209
PubMed 16990383
Re: Gender-associated risk factors for cardiac end points and total mortality after renal transplantation
Clin Transplant, 20 (5), 665
PubMed 16968495
Publications 2005
Autologous stem cell transplantation in acute myocardial infarction: The ASTAMI randomized controlled trial. Intracoronary transplantation of autologous mononuclear bone marrow cells, study design and safety aspects
Scand Cardiovasc J, 39 (3), 150-8
PubMed 16152682
[Norwegian Society of Cardiology and international guidelines]
Tidsskr Nor Laegeforen, 125 (8), 1047
PubMed 15852098
Publications 2004
Coronary artery aneurysms mimicking cardiac tumor
Eur J Echocardiogr, 5 (4), 308-12
PubMed 15219546
Cardiovascular disease in stable renal transplant patients in Norway: morbidity and mortality during a 5-yr follow-up
Clin Transplant, 18 (5), 596-604
PubMed 15344967
[Cardiology as a major specialty]
Tidsskr Nor Laegeforen, 124 (13-14), 1829
PubMed 15229694
Publications 2001
Regional myocardial systolic function during acute myocardial ischemia assessed by strain Doppler echocardiography
J Am Coll Cardiol, 37 (3), 726-30
PubMed 11693743
Metabolic cardiovascular syndrome after renal transplantation
Nephrol Dial Transplant, 16 (5), 1047-52
PubMed 11328915
Myocardial performance after transmyocardial revascularization with CO(2)laser. A dobutamine stress echocardiographic study
Eur J Echocardiogr, 2 (3), 187-96
PubMed 11882452
Publications 2000
Acute regional myocardial ischemia identified by 2-dimensional multiregion tissue Doppler imaging technique
J Am Soc Echocardiogr, 13 (11), 986-94
PubMed 11093100
Sublingual nitroglycerin delays arterial wave reflections despite increased aortic >stiffness> in patients with hypertension: a Doppler echocardiography study
J Am Soc Echocardiogr, 13 (12), 1100-8
PubMed 11119278
Cardiac output measurements during cross-clamping of the descending thoracic aorta in pigs. A comparison between transit-time ultrasound, thermodilution and pulsed Doppler ultrasound
Acta Anaesthesiol Scand, 44 (2), 180-5
PubMed 10695912
Publications 1999
Reversal of intraventricular flow propagation during isovolumic relaxation: A marker of anterior wall dysfunction
J Am Soc Echocardiogr, 12 (10), 801-10
PubMed 10511648
[Cardiovascular disease after kidney transplantation]
Tidsskr Nor Laegeforen, 119 (25), 3784-8
PubMed 10574058
Total arterial compliance in ambulatory hypertension during selective beta1-adrenergic receptor blockade and angiotensin-converting enzyme inhibition
J Cardiovasc Pharmacol, 33 (2), 273-9
PubMed 10028936
Cardiovascular morbidity and risk factors in renal transplant patients
Nephrol Dial Transplant, 14 (3), 648-54
PubMed 10193814
Publications 1998
Left ventricular volumes assessed by different new three-dimensional echocardiographic methods and ordinary biplane technique
Int J Card Imaging, 14 (1), 55-63
PubMed 9559379
Influence of body size and left ventricular ejection dynamics on total arterial compliance determined using Doppler echocardiography and subclavian artery pulse tracings in healthy humans
Blood Press, 7 (4), 239-46
PubMed 9858116
Publications 1997
How does computer-assisted digital wall motion analysis influence observer agreement and diagnostic accuracy during stress echocardiography?
Int J Card Imaging, 13 (2), 105-14
PubMed 9110190
Publications 1996
Evaluation of reference systems for quantitative wall motion analysis from three-dimensional endocardial surface reconstruction: an echocardiographic study in subjects with and without myocardial infarction
Am J Card Imaging, 10 (4), 244-53
PubMed 9012392
Hemodynamics in white coat hypertension compared to ambulatory hypertension and normotension
Am J Hypertens, 9 (11), 1090-8
PubMed 8931834
Effect of sodium nitroprusside on cerebral haemodynamics during cross-clamping of the descending thoracic aorta in pigs
Eur J Surg, 162 (4), 329-34
PubMed 8739421
The importance of transesophageal echocardiography during surgery of the thoracic aorta
Eur J Vasc Endovasc Surg, 12 (4), 401-6
PubMed 8980426
Systemic arterial compliance early and late after a first acute myocardial infarction
Cardiology, 87 (5), 415-22
PubMed 8894263
Hyperlipidaemia in renal transplant patients
J Intern Med, 239 (5), 407-15
PubMed 8642233
Publications 1995
Comparison of digital dipyridamole stress echocardiography and upright bicycle stress echocardiography for identification of coronary artery stenosis
Cardiology, 86 (6), 514-20
PubMed 7585764
Digital high frame rate stress echocardiography for detection of coronary artery stenosis by high dose dipyridamole stress testing
Int J Card Imaging, 11 (3), 163-70
PubMed 7499905
Effect of sodium nitroprusside on cardiac output during cross-clamping of the descending thoracic aorta in pigs
Eur Surg Res, 27 (5), 323-31
PubMed 7589004
Systemic cardiovascular response in hemodialysis without and with ultrafiltration with membranes of high and low biocompatibility
Blood Purif, 13 (5), 229-40
PubMed 7546525
Cardiovascular response in patients with and without myocardial ischaemia during dobutamine echocardiography stress test for coronary artery disease
Clin Physiol, 15 (3), 249-63
PubMed 7621647
Increased left ventricular contractility during cross-clamping of the descending thoracic aorta
J Cardiothorac Vasc Anesth, 9 (5), 497-502
PubMed 8547548
Publications 1994
Model-based estimation of vascular parameters: evaluation of robustness and suitability of models
Echocardiography, 11 (4), 409-23
PubMed 10150623
Calcitonin gene-related peptide (human alpha-CGRP) counteracts vasoconstriction in human subarachnoid haemorrhage
Neurosci Lett, 170 (1), 67-70
PubMed 8041516
Angiographic findings of silent ischaemia following aortocoronary bypass surgery
Cardiovasc Surg, 2 (3), 398-402
PubMed 8049984
Exercise tolerance and work ability following aorto-coronary bypass surgery
Scand J Soc Med, 22 (4), 303-8
PubMed 7716442
Three-dimensional echocardiography for quantitative left ventricular wall motion analysis: a method for reconstruction of endocardial surface and evaluation of regional dysfunction
Echocardiography, 11 (4), 397-408
PubMed 10150622
Three-dimensional echocardiography for quantitative left ventricular wall motion analysis: a method for reconstruction of endocardial surface and evaluation of regional dysfunction
Echocardiography, 11 (4), 397-408
PubMed 10147323
Noninvasive study of left ventricular function and systemic haemodynamics during dipyridamole echocardiography stress test
Clin Physiol, 14 (5), 581-94
PubMed 7820982
A new method for echocardiographic computerized three-dimensional reconstruction of left ventricular endocardial surface: in vitro accuracy and clinical repeatability of volumes
J Am Soc Echocardiogr, 7 (6), 571-81
PubMed 7840984
Publications 1993
Digital dipyridamole stress echocardiography in silent ischemia after coronary artery bypass grafting and/or after healing of acute myocardial infarction
Am J Cardiol, 72 (9), 640-6
PubMed 8249837
Noninvasive computerized assessment of left ventricular performance and systemic hemodynamics by study of aortic root pressure and flow estimates in healthy men, and men with acute and healed myocardial infarction
Am J Cardiol, 72 (3), 260-7
PubMed 8342502
Non-invasive estimates of aortic root pressures: external subclavian arterial pulse tracing calibrated by oscillometrically determined brachial arterial pressures
Clin Physiol, 13 (6), 573-86
PubMed 8119052
Publications 1991
Anterior perforations in lumbar discectomies. A report of four cases of vascular complications and a CT study of the prevertebral lumbar anatomy
Spine (Phila Pa 1976), 16 (1), 54-60
PubMed 2003238
Publications 1990
[Ultrasonography of strangulated Richter's hernia]
Tidsskr Nor Laegeforen, 110 (26), 3348-9
PubMed 2256054
[Chloroquine poisoning]
Tidsskr Nor Laegeforen, 110 (4), 488-9
PubMed 2309198




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