Publication in Nature Genetics on testicular cancer susceptibility

 
R.I. Skotheim
R.I. Skotheim
Researchers from Department of Cancer Prevention, Institute for Cancer Research and Centre for Cancer Biomedicine are involved in an international consortium on genetics of testicular germ cell tumours. The testicular cancer consortium, which is directed from National Cancer Institute and University of Pennsylvania, recently published two articles in Nature Genetics (Chung et al., May 2013) and Human Molecular Genetics (Schumacher et al., March 2013) respectively.
Rolf Skotheim (photo) is the site responsible in Oslo, and says that across all types of cancer, testicular cancer is now the type for which known susceptibility genes explain the largest fraction the genetic risk.

More  
 
 

PhD student Deeqa Ahmed profiled in Uniforum

 

Research by PhD student Deeqa Ahmed and colleagues at the Department of Cancer Prevention may provide improved colorectal cancer diagnostics. Identification of a set of biomarkers that has been licensed by Oxford Gene Technology may lead to new tests for early cancer detection.

Full story in Norwegian.


More  
 
 

Awards from Oslo University Hospital to outstanding researchers

 

New group leader Guro E Lind received "Early Career award" from Oslo University hospital. Post doc Anita Sveen and colleagues were honored for "Excellent original article".


More  
 
 

Research based innovation

 

Department of Cancer Prevention receives funding from the Norwegian Research Council from the FORNY2020 and BIOTEK2021 programmes for innovation projects on colorectal cancer. Development of prognostic and predictive markers for CRC is led by professor Ragnhild A. Lothe with Dr.s Rolf I. Skotheim, Guro E. Lind and professor Arild Nesbakken as active partners.

Project presentation in Norwegian

Link til Dept Cancer prevention
Link til CCB


More  
 
 

Comprehensive review on molecular biology of germ cell tumors of the ovary

 

Drs Sigrid Marie Kraggerud, Christina Høi-Hansen and Sharmini Alagaratnam publish in Endrocrine Reviews, the highest ranked journal in the category of Endocrinology and metabolism with IF of 19.9.


More  
 
 

Group leader Guro E. Lind invited to Ekko, NRK P2

 

Monday the 9th of April, Lind was invited to the radio program “Ekko” to talk about blood based testing for early detection of colorectal cancer.
The program (in Norwegian) can be heard here: nrk_ekko_-_et_aktuelt_samfunnsprogram_2013-0408-1238_6350102183.mp3


More  
 
 

Ragnhild A. Lothe appointed "Innovator of the month" by Helse Sør-Øst for March 2013

 
The South-Eastern Norway Regional Health Authority (Helse Sør-Øst) profiles ongoing innovation paths in the region by calling special attention to an "Innovator of the Month".

For the month of March 2013, this honor goes to professor Ragnhild A.Lothe, Genetics group, Department of Cancer Prevention at the Institute for Cancer Research.

From the web pages of South-Eastern Norway Regional Health Authority (in Norwegian):
Innovator of the month

More  
 
 

Alagaratnam article published in Stem Cells and Development

 
Sharmini Alagaratnam has worked both for the Norwegian Research Council’s Program for Stem Cell Research, and the Cancer Stem Cell Innovation Center CAST, on a project to identify malignancy genes in stem cells. Part of this work has recently been published in the journal Stem Cells and Development, and represents the first direct comparison of gene expression in embryonic stem cells and their malignant counterpart, embryonal carcinoma, cultured under identical conditions. This was a collaborative study between the Molecular Genetics and the Genome Biology groups at the Department of Cancer Prevention.

A gene signature distinguishing the two cell types was identified, which included a number of cancer relevant and pluripotency genes. NR5A2 is an especially intriguing candidate given its role in the WNT-signalling pathway, which is often disrupted in cancer, and particularly so in colorectal cancer.

Link to article

More  
 
 

Shiva Dahal-Koirala awarded Master’s degree

 
Congratulations to Shiva Dahal-Koirala, who defended her Master’s thesis on the 18th of December 2012 at the Institute for Molecular Biosciences, University of Oslo.

More  
 
 

Scientists at Department of Cancer Prevention awarded prize for Excellent Research Article

 

A study carried out at Edward Leithe’s project group at Department of Cancer Prevention has been awarded a prize for Excellent Research Article by the Oslo University Hospital. The prize was presented on Friday 26th October and carries an award of 50,000 kr.


More  
 
Previous news
 Breaking advances in prognostic testing of colorectal cancer  
 New group in Epigenetics established at the Institute for Cancer Research, Dept of Cancer Prevention  
 Ragnhild A. Lothe selected Scientist of the Month  
 ColoGuideEx receives attention  
 Ane Hansen Kjenseth successfully defended her PhD thesis  
 Ina Andrassy Eilertsen awarded Master’s degree  
 Study by Ane Hansen Kjenseth et al. featured on the cover of Journal of Biological Chemistry  
 Anita Sveen and Trude Holmeide Ågesen successfully defended their PhD theses  
 British biotech company signs agreement with Inven2 to secure exclusive rights to biomarkers identified in the Lothe group  
 New gene-based prognostic test for colorectal cancer  
 The Norwegian Oncology Forum’s Young Researcher award 2011 to Guro E. Lind  
 Stine Aske Danielsen successfully defends her PhD thesis  
 Andreas Hoff and Peter Eide awarded Master’s degree  
 Researchers from Department of Cancer Prevention reveal importance for transcriptome instability in colorectal cancer  
 Solveig Sirnes successfully defends her PhD thesis  
 Ragnhild A. Lothe elected to the EACR Council  
 Marianne Berg - Excellent trial lecture for PhD  
 Maren Høland graduated  
 Tone Aase Fykerud graduated  
 Forskning om nerveskjedesvulster omtalt på forskningsrådets hjemmeside  
 Translational research on colorectal cancer within Oslo University hospital featured in Dagbladet newspaper  
 Molecular Genetics group publishes in Journal of Clinical Oncology  
 MSc degree to Anne Cathrine Bakken  
 Dr. Ragnar Mørk legacy prize 2009 to Rolf I. Skotheim  
 Novel regulatory mechanism for intercellular communication identified  
 The biomarker project in Aftenposten  
 Interview with Guro Lind in Apollon  
 Disputation and trial lecture - Terje Cruickshank Ahlquist  
 Stine Danielsen awarded poster prize at the 30th Scandinavian Sarcoma Group Meeting  
 Mutations in the Neurofibromin gene, an inhibitor of KRAS  
 New microarray design for detection of fusion genes  
 Ahlquist and colleagues identify time of occurrence of specific methylation events in colorectal development.  
 Marthe Eken graduated  
 Interview with Ragnhild Lothe on national television [in Norwegian]  
 Skotheim - First runner up to Idea Prize 2008  
 Young Investigator Award to Rolf Skotheim  
 Congratulations to Jarle Bruun  
 Invited speaker at Biomarker Discovery Conference  
 Dietary effects on genes - National Broadcasting Company  
 In thin air - The annual mountain trip  
 ”Signaling in colorectal cancer”. Two recent papers by PhD students Stine A. Danielsen and Terje Ahlquist and colleagues  
 On the road again  
 Interview with Guro E. Lind in Universitas  
 Cancer Prevention - on thin ice...  
 Novel effects of chemical carcinogens on intercellular communication identified  
 State visit to Portugal, May 2008.  
 Master student Hilde Honne graduated  
 Masterstudenter intervjuet  
 What is epigentics? - National Broadcasting Company  
 Medinnova Idea Prize 2007 - presentation in Onkonytt  
 Rolf I. Skotheim appointed visiting professor in Finland  
 Medinnova's Idea Prize to research group working on early markers for tumors in the digestive system  
 Edgar Rivedal elected member of scientific council of IARC  
 Ragnhild A Lothe awarded the "King Olav V's Cancer Research Award"  
 King Olav V’s prize for cancer research 2007 awarded to Ragnhild A. Lothe  
 Center for Cancer Biomedicine funded  
 New cancer review journal edited at RR-Medical Centre: Critical Reviews in Oncogenesis  
 Porto – Oslo collaboration publishes improved prognostication by genetic analyses of prostate cancer  
 CoE-applicant from the Institute for cancer research to final round  
 New Department  
 Lothe group participant in a new Centre of Sciencebased Innovation  
 New data from an international collaborative study on TP53 and colorectal cancer, including data from the Lothe lab  
 Kristine Kleivi interviewed by the Norwegian Cancer Society  
 Ragnhild Lothe new member of the Commission for Forensic Medicine  
 Funding provided by Helse Sør  
 Disputation and trial lecture - Kristine Kleivi  
 Disputation and trial lecture - Guro E. Lind  
 Cover article in Neoplasia by Lin Thorstensen and coworkers. February 2005.  
 Ragnhild Lothe's group supported from National Cancer Plan  
 Media