PhD and MSc dissertations from Department of Cancer Prevention

Degrees at Department of Cancer Prevention (from 2006 to date)

PhD



Trude Holmeide Ågesen , 2012, PhD. Faculty of Medicine, University of Oslo. Title: Genetics of colorectal cancer: new insights to early onset and to prognostication of disease. Supervisor, Ragnhild A. Lothe.
Anita Sveen, 2012, PhD. Faculty of Mathematics and Natural Sciences, University of Oslo. Title: The transcriptome and prognosis in stage II and III colorecal cancer. Supervisor, Rolf I. Skotheim.
Stine Aske Danielsen, 2011, PhD. Faculty of Medicine, University of Oslo. Title: Molecular markers of colorectal cancer and their clinical potential. Supervisor, Ragnhild A. Lothe; co-supervisor, Guro E. Lind.
Solveig Sirnes, 2011, PhD. Faculty of Medicine, University of Oslo. Title: Gap junctions in development of colorectal cancer. Supervisor, Edgar Rivedal; co-supervisor, Edward Leithe.
Helge R Brekke, 2010, PhD. Faculty of Medicine, University of Oslo. Title: New insights into the biology of Malignant Peripheral Nerve Sheath Tumors identify biomarkers for disease outcome. Supervisor, Ragnhild A. Lothe.
 
Marianne Berg, 2010, PhD. Faculty of Medicine, University of Oslo. Title: Genomics of colorectal carcinomas from young and elderly patients. Supervisor, Ragnhild A. Lothe.
Terje Ahlquist, 2009, PhD.  Faculty of Medicine, University of Oslo. Title: Novel genetic and epigenetic alterations in colorectal tumors and their potential as biomarkers. Supervisor, Ragnhild A. Lothe.
Edward Leithe, 2006, PhD. Faculty of Medicine, University of Oslo. Title: Regulation of the gap junction protein connexin43 by phosphorylation and ubiquitination. Supervisor: Edgar Rivedal.


Foreign PhD

  • Vera Lucia Marques Costa, PhD, Abel Salazar Biomedical Sciences Institute, University of Porto, 2010. Development of epigentic-based markers for molecular detection of urological cancers.Supervisor Carmen Jeronimo, co-supervisor Manuel R. Teixeira, co-supervisor Ragnhild A.Lothe


  • Franclim Ricardo da Silva Ribeiro, PhD, Institute of Biomedical Sciences, University of Porto, 2006. Diagnostic and prognostic value of molecular cytogenetics analyses of sextant biopsies from prostate cancer suspects. Supervisor Manuel Teixeira, co-supervisor Ragnhild A Lothe


MSc



Bjarne Johannessen, 2011, MSc, Deptartment of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo. Title: Identification of cancer-specific transcripts by computational analysis of genome-scale expression data at exon resolution. Supervisor: Rolf I. Skotheim; co-supervisors: Gard Thomassen.
Hege Marie Vedeld, 2011, MSc, Deptartment of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo. Title: DNA methylation biomarkers for colorectal cancer detection: CDO1, DCLK1, ZNF331 and ZSCAN18. Supervisor: Guro E. Lind.
Peter Eide, 2011, MSc, Deptartment of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo. Title: HECT E3 ubiquituin ligases in regulation of colon cancer cell growth and mitogenic signaling pathways. Supervisor: Edward Leithe; co-supervisor: Ragnhild A. Lothe.
Andreas Hoff, 2011, MSc, Deptartment of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo. Title: Transcript variation and protein expression in testicular germ cell tumours. Supervisor: Sharmi Alagaratnam; co-supervisors: Rolf Skotheim.
Tone Aase Fykerud, 2010, MSc, Deptartment of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo. Title: Regulation of the gap junction protein connexin43 by members of the Nedd4 E3 ubiquitin ligase family. Supervisor: Edward Leithe; co-supervisors: Edgar Rivedal and Ragnhild A. Lothe.

Maren Høland, 2010, MSc, Deptartment of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo. Title: Prognostic value of protein markers in malignant peripheral nerve sheath tumours. Supervisor, Matthias Kolberg; co-supervisor, Ragnhild A. Lothe.
Marianne Guriby, 2010, MSc, Department of Chemistry, Biotechnology, and Food Science, University of Life Sciences. Title: New epigenetic biomarkers examined for added value in lymph node diagnostics of colon cancer. Supervisor, Terje Q. Ahlquist; co-supervisor, Ragnhild A. Lothe.
Deeqa Ahmed, 2010, MSc, Department of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo. Title: Identification of novel epigenetic biomarkers in colorectal cancer, GLDC and PPP1R14A. Supervisor, Guro E Lind; co-supervisor, Ragnhild A Lothe.
Anne Cathrine Bakken, 2009, MSc, Deptartment of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo. Title: Qualitative transcript variation in cancer. Supervisor, Rolf I. Skotheim; co-supervisor, Ragnhild A. Lothe.
Marthe Eken, 2008, MSc, Deptartment of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo. Title: Identification of cancer-specific transcripts: With emphasis on the hunt for fusion genes in colorectal cancer. Supervisor: Rolf I Skotheim, co-supervisor: Ragnhild A Lothe
Jarle Bruun, 2008, MSc, Department of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo. Title: Effect of Connexin43 transfection on growth characteristics of the human colon adenocarcinoma cell line HT29. Supervisor: Edward Leithe, co-supervisor: Edgar Rivedal.
Hilde Honne, 2008, MSc, Department of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo, June 2008. Title: Identification of novel epigenetic biomarkers in colorectal cancer. Supervisor: Guro E Lind, co-supervisor: Ragnhild A Lothe

Ellen Christine Røyrvik, 2007, MSc, Department of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo, Title: Slip Slidin'Away: Mutations in colorectal cancer with microsatellite instability. Supervisor: Ragnhild A. Lothe, co-supervisor: Terje Ahlquist.
Stine Aske Danielsen, 2006, MSc, Department of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo.  Title: Analysis of potential master keys in colorectal, testicular and malignant peripheral nerve sheath tumors. Supervisor: Ragnhild A. Lothe, co-supervisor: Guro E.Lind.

Previous degrees from Lothe and Rivedal lab (prior to 2006)

PhD

  • Kristine Kleivi, , Dr. Philos, Faculty of Medicine, University of Oslo, 2006. "Genome and transcriptome profiles of primary and advanced colorectal carcinomas" (Supervisor Ragnhild A Lothe)
  • Guro E. Lind, Dr. Philos, Faculty of Medicine, University of Oslo, 2005. "DNA methylation in cancer development - Lessons learned from tumors of the testis and the large bowel" (Supervisor Ragnhild A Lothe)
  • Sigrid Marie Kraggerud, Dr. Philos, Faculty of Medicine, University of Oslo, 2003. "Pathogenesis of Germ Cell Tumors of the Testis and Ovary" (Supervisor Ragnhild A Lothe)
  • Chieu B. Diep, Dr. Philos, Faculty of Medicine, University of Oslo, 2003. "Molecular genetics of colorectal cance. Prognostic markers and novel metastasis-specific alterations" (Supervisor Ragnhild A Lothe)
  • Rolf I. Skotheim, Dr. Philos, Faculty of Medicine, University of Oslo, 2003. "Molecular biology of testicular germ cell tumors - New insights into a genetic developmental model" (Supervisor Ragnhild A Lothe)
  • Lin Thorstensen, Dr. Philos, Faculty of Medicine, University of Oslo, 2001. "Genetic Changes in Primary Colorectal Carcinomasa and Metastases. Left- and Right-sided Carcinogenesis" (Supervisor Ragnhild A Lothe)

Foreign PhD

  • Patricia Manuel Costa e Castro, PhD, Faculty of Medicine, University of Porto, 2005. ”Molecular Biology of chromosomal instability phenotype of follicular cell thyroid tumours” (Supervisor Manuel Sobrinho Simões, co-supervisor Ragnhild A Lothe)

MSc

  • Helge R. Brekke, MSc (Cand. Scient), Cell Biology, Department of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo, December 2004. "Malignant Peripheral Nerve Sheath tumors - Amplicon search by FISH and protein expression profiling using tissue micro array" (Supervisor Ragnhild A Lothe)
  • Terje Ahlquist, MSc (Cand. Scient), Cell Biology, Department of Molecular Biosciences, The Faculty of Mathematics and Natural Sciences, University of Oslo, October 2004. "Genetic and epigenetic markers in precursor lesions of colorectal cancer" (Supervisor Ragnhild A Lothe)
  • Trude Holmeide Ågesen, MSc (Cand.Scient), Cell Biology, Department of Botany, Norwegian University of Science and Technology, Trondheim, 2002 “Protein expression and genome profiling of malignant peripheral nerve sheath tumours” (Supervisor Ragnhild A Lothe)
  • Kristine Kleivi, MSc (Cand.Scient) Institute of Biology, Division of General Genetics, The Faculty of Mathematics and Natural Sciences, University of Oslo, 2001. "Genome profiles of breast- and colorectal carcinomas" (Supervisor Ragnhild A Lothe, co-supervisor Manuel Teixeira)
  • Guro E. Lind, MSc (Cand. Scient) Institute of Biology, Division of General Genetics, The Faculty of Mathematics and Natural Sciences, University of Oslo, 2001. "Genetic and epigenetic changes in cancers of the male reproductive organs" (Supervisor Ragnhild A Lothe)
  • Rolf I. Skotheim, MSc (Cand.Scient) Institute of Biology, Division of General Genetics, The Faculty of Mathematics and Natural Sciences, University of Oslo, 2000. "Genetic alterations in testicular germ cell tumours" (Supervisor Ragnhild A Lothe)
  • Chieu B. Diep, MSc (Cand. Pharm) Institute of Pharmacy, University of Oslo, 1998. "Tumorgenotyper som prognostiske markører ved colorectal cancer" [in Norwegian] (Supervisor Ragnhild A Lothe)
  • Hanne Opsahl, 1998, Cand. scient. Gap junction intercellular communication measure by “scrape-loading” and image analyses. Norwegian University of Science and Technology, Trondheim. Supervisor Edgar Rivedal.
  • Lin Thorstensen, MSc (Cand. Pharm) Institute of Pharmacy, University of Oslo, 1996. "Genetiske forandringer i avanserte svulster fra tykktarm og endetarm" [in Norwegian] (Supervisor Ragnhild A Lothe)
  • Ellen Morrison, 1996, Cand. scient. Basic fibroblast growth factor and morphological transformation of Syrian hamster embryo derived cells. University of Oslo, Faculty of Mathematics and Natural Sciences. Supervisor, Edgar Rivedal.
  • Gunnhild Vikhamar, 1996, Cand. scient. Gap junction intercellular communication and epidermal growth factor. University of Oslo, Faculty of Mathematics and Natural Sciences. Supervisor, Edgar Rivedal.