Publications
Publications published since 2006 or in press from OUS - Department of Cancer Prevention
143 publications found
Publications in press
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Meta-analysis identifies four new loci associated with testicular germ cell tumor
Nat Genet (in press)
PubMed 23666239 -
Molecular Characteristics of Malignant Ovarian Germ Cell Tumors and Comparison With Testicular Counterparts: Implications for Pathogenesis
Endocr Rev (in press)
PubMed 23575763 -
Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23
Hum Mol Genet (in press)
PubMed 23462292
Publications 2013
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Transforming pluripotency: an exon-level study of malignancy-specific transcripts in human embryonal carcinoma and embryonic stem cells
Stem Cells Dev, 22 (7), 1136-46
PubMed 23137282 -
NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway
Cell Signal, 25 (1), 12-8
PubMed 22974840 -
Survival meta-analyses for >1800 malignant peripheral nerve sheath tumor patients with and without neurofibromatosis type 1
Neuro Oncol, 15 (2), 135-47
PubMed 23161774 -
The mitochondrial and autosomal mutation landscapes of prostate cancer
Eur Urol, 63 (4), 702-8
PubMed 23265383 -
Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene ?-catenin
EMBO Rep, 14 (1), 10-1
PubMed 23229585 -
Microsatellite instability has a positive prognostic impact on stage II colorectal cancer after complete resection: results from a large, consecutive Norwegian series
Ann Oncol, 24 (5), 1274-82
PubMed 23235802 -
Frequent copy number gains at 1q21 and 1q32 are associated with overexpression of the ETS transcription factors ETV3 and ELF3 in breast cancer irrespective of molecular subtypes
Breast Cancer Res Treat, 138 (1), 37-45
PubMed 23329352 -
The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man
Cancer Cell, 23 (1), 35-47
PubMed 23260764
Publications 2012
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ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis
Gut, 61 (11), 1560-7
PubMed 22213796 -
A tissue-based comparative effectiveness analysis of biomarkers for early detection of colorectal tumors
Clin Transl Gastroenterol, 3, e27
PubMed 23324654 -
Novel target genes and a valid biomarker panel identified for cholangiocarcinoma
Epigenetics, 7 (11), 1249-57
PubMed 22983262 -
Probability of metachronous testicular cancer in patients with biopsy-proven intratubular germ cell neoplasia depends on first-time treatment of germ cell cancer
J Clin Oncol, 30 (32), 4004-10
PubMed 23071246 -
Potential downstream target genes of aberrant ETS transcription factors are differentially affected in Ewing's sarcoma and prostate carcinoma
PLoS One, 7 (11), e49819
PubMed 23185447 -
MiR-9, -31, and -182 deregulation promote proliferation and tumor cell survival in colon cancer
Neoplasia, 14 (9), 868-79
PubMed 23019418 -
Survey of 548 oncogenic fusion transcripts in thyroid tumors supports the importance of the already established thyroid fusions genes
Genes Chromosomes Cancer, 51 (12), 1154-64
PubMed 22961909 -
Smad ubiquitination regulatory factor-2 controls gap junction intercellular communication by modulating endocytosis and degradation of connexin43
J Cell Sci, 125 (Pt 17), 3966-76
PubMed 22623726 -
Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis
Proc Natl Acad Sci U S A, 109 (28), 11252-7
PubMed 22730461 -
ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth
J Clin Invest, 122 (12), 4621-34
PubMed 23143306 -
MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR
J Transl Med, 10, 36
PubMed 22390413 -
The gap junction channel protein connexin 43 is covalently modified and regulated by SUMOylation
J Biol Chem, 287 (19), 15851-61
PubMed 22411987 -
Endocytosis and post-endocytic sorting of connexins
Biochim Biophys Acta, 1818 (8), 1870-9
PubMed 21996040 -
Vimentin in upper gastrointestinal pathologies--letter
Cancer Epidemiol Biomarkers Prev, 21 (10), 1889; author reply 1890
PubMed 22929079 -
Oncogenicity of the developmental transcription factor Sox9
Cancer Res, 72 (5), 1301-15
PubMed 22246670 -
Nuclear translocation and functions of growth factor receptors
Semin Cell Dev Biol, 23 (2), 165-71
PubMed 21930229 -
Prognostic relevance of occult metastases detected by cytokeratin 20 and mucin 2 mRNA levels in sentinel lymph nodes from colon cancer patients
Ann Surg Oncol, 19 (12), 3719-26
PubMed 22752373 -
Whole-transcriptome sequencing identifies novel IRF2BP2-CDX1 fusion gene brought about by translocation t(1;5)(q42;q32) in mesenchymal chondrosarcoma
PLoS One, 7 (11), e49705
PubMed 23185413 -
FLI1 is a novel ETS transcription factor involved in gene fusions in prostate cancer
Genes Chromosomes Cancer, 51 (3), 240-9
PubMed 22081504 -
Molecular subtyping of primary prostate cancer reveals specific and shared target genes of different ETS rearrangements
Neoplasia, 14 (7), 600-11
PubMed 22904677 -
Studies of ribonucleotide reductase in crucian carp-an oxygen dependent enzyme in an anoxia tolerant vertebrate
PLoS One, 7 (8), e42784
PubMed 22916159 -
Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
Int J Cancer, 131 (3), 570-81
PubMed 21866551 -
Prognostic impact of lymph node harvest and lymph node ratio in patients with colon cancer
Dis Colon Rectum, 55 (3), 307-15
PubMed 22469798 -
[Genome sequencing for personalized cancer treatment]
Tidsskr Nor Laegeforen, 132 (21), 2406-8
PubMed 23160594 -
The exon-level biomarker SLC39A14 has organ-confined cancer-specificity in colorectal cancer
Int J Cancer, 131 (6), 1479-85
PubMed 22173985 -
ColoGuidePro: a prognostic 7-gene expression signature for stage III colorectal cancer patients
Clin Cancer Res, 18 (21), 6001-10
PubMed 22991413
Publications 2011
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Quantitative validation of GJC1 promoter hypermethylation in benign and malignant colorectal tumors
Endocr Relat Cancer, 18 (6), C31-4
PubMed 21868474 -
The testicular germ cell tumour transcriptome
Int J Androl, 34 (4 Pt 2), e133-50; discussion e150-1
PubMed 21651573 -
Genetic and epigenetic traits as biomarkers in colorectal cancer
Int J Mol Sci, 12 (12), 9426-39
PubMed 22272141 -
Prevention: will an aspirin a day keep the colorectal cancer away?
Nat Rev Clin Oncol, 8 (3), 130-1
PubMed 21200396 -
Coexpression and nuclear colocalization of metastasis-promoting protein S100A4 and p53 without mutual regulation in colorectal carcinoma
Amino Acids, 41 (4), 875-84
PubMed 20191297 -
Primary sclerosing cholangitis and malignancy
Best Pract Res Clin Gastroenterol, 25 (6), 753-64
PubMed 22117640 -
Androgen substitution with testosterone undecanoate in survivors of bilateral testicular cancer requires individually-adjusted injection intervals
BJU Int, 107 (7), 1080-7
PubMed 20825398 -
TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers
Epigenetics, 6 (9), 1120-30
PubMed 21847011 -
Phospholipase C isozymes are deregulated in colorectal cancer--insights gained from gene set enrichment analysis of the transcriptome
PLoS One, 6 (9), e24419
PubMed 21909432 -
Ischemia induces closure of gap junctional channels and opening of hemichannels in heart-derived cells and tissue
Cell Physiol Biochem, 28 (1), 103-14
PubMed 21865853 -
Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas
Mol Cancer, 10, 85
PubMed 21777459 -
SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
Oncogene, 30 (37), 3967-78
PubMed 21499309 -
Fusion gene microarray reveals cancer type-specificity among fusion genes
Genes Chromosomes Cancer, 50 (5), 348-57
PubMed 21305644 -
Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting
Traffic, 12 (9), 1211-26
PubMed 21564451 -
Norepinephrine inhibits intercellular coupling in rat cardiomyocytes by ubiquitination of connexin43 gap junctions
Cell Commun Adhes, 18 (4), 57-65
PubMed 21936631 -
MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines
BMC Cancer, 11, 211:1-11
PubMed 21624110 -
Cysteine-rich secretory protein-3 (CRISP3) is strongly up-regulated in prostate carcinomas with the TMPRSS2-ERG fusion gene
PLoS One, 6 (7), e22317
PubMed 21814574 -
A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
PLoS One, 6 (3), e17086
PubMed 21455500 -
DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer
Epigenetics, 6 (5), 602-9
PubMed 21406965 -
Peritoneal carcinomatosis of colon cancer origin: highest incidence in women and in patients with right-sided tumors
J Surg Oncol, 104 (7), 792-7
PubMed 21547915 -
Advances in the Understanding and Treatment of Colorectal Cancer
Discov. Med., 66, 393-404 -
Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival
Genome Med, 3 (5), 32
PubMed 21619627 -
CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer
Genes Immun, 12 (8), 653-62
PubMed 21716316
Publications 2010
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Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci
Mol Cancer, 9, 100
PubMed 20459617 -
DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset
PLoS One, 5 (11), e13978
PubMed 21103049 -
Genomic changes in chromosomes 10, 16, and X in malignant peripheral nerve sheath tumors identify a high-risk patient group
J Clin Oncol, 28 (9), 1573-82
PubMed 20159821 -
Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors
J Carcinog, 9, 1
PubMed 20411023 -
Increased miR-21 expression during human monocyte differentiation into DCs
Front Biosci (Elite Ed), 2, 818-28
PubMed 20515755 -
Three epigenetic biomarkers, GDF15, TMEFF2, and VIM, accurately predict bladder cancer from DNA-based analyses of urine samples
Clin Cancer Res, 16 (23), 5842-51
PubMed 20975101 -
Regulation of gap junction intercellular communication by the ubiquitin system
Cell Signal, 22 (9), 1267-73
PubMed 20206687 -
UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
Autophagy, 6 (7), 863-70
PubMed 20724836 -
Inhibition of connexin 43 gap junction channels by the endocrine disruptor ioxynil
Toxicol Appl Pharmacol, 247 (1), 10-7
PubMed 20510257 -
Genomic aberrations in borderline ovarian tumors
J Transl Med, 8, 21
PubMed 20184781 -
Array-CGH analysis of microdissected chromosome 19 markers in ovarian carcinoma identifies candidate target genes
Genes Chromosomes Cancer, 49 (11), 1046-53
PubMed 20725991 -
Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin
BMC Cancer, 10, 587
PubMed 20979647 -
Gap junction intercellular communication and benzene toxicity
Chem Biol Interact, 184 (1-2), 229-32
PubMed 19932693 -
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
Nat Cell Biol, 12 (4), 362-71
PubMed 20208530 -
Profiling of miRNA expression and prediction of target genes
Methods Mol Biol, 629, 257-71
PubMed 20387154 -
The B[a]P-increased intercellular communication via translocation of connexin-43 into gap junctions reduces apoptosis
Toxicol Appl Pharmacol, 242 (2), 231-40
PubMed 19874837 -
Tiling array analysis of UV treated Escherichia coli predicts novel differentially expressed small peptides
PLoS One, 5 (12), e15356
PubMed 21203457 -
Molecularly targeted therapies for colorectal cancer: Strategies for implementing translational research in clinical trials
Curr Opin Mol Ther, 12 (6), 703-11
PubMed 21154162
Publications 2009
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New doctorial cancer research:novel genetic and epigenetic alterations in colorectal tumors and their potential as biomarkers
Crit Rev Oncog, 15 (1), 81-3
PubMed 20092436 -
TPD52, a candidate gene from genomic studies, is overexpressed in testicular germ cell tumours
Mol Cell Endocrinol, 306 (1-2), 75-80
PubMed 19041365 -
Germline and somatic NF1 mutations in sporadic and NF1-associated malignant peripheral nerve sheath tumours
J Pathol, 217 (5), 693-701
PubMed 19142971 -
Autophagy in tumour suppression and promotion
Mol Oncol, 3 (4), 366-75
PubMed 19559660 -
Identification of p53 as a strong predictor of survival for patients with malignant peripheral nerve sheath tumors
Neuro Oncol, 11 (5), 514-28
PubMed 19182148 -
Monitoring B cell response to immunoselected phage-displayed peptides by microarrays
Methods Mol Biol, 524, 273-85
PubMed 19377952 -
Novel Mutations of the Suppressor Gene PTEN in Colorectal Carcinomas Stratified by Microsatellite Instability- and TP53 Mutation- Status (vol 29, pg E252, 2008)
Hum. Mutat., 30 (6), 1023 -
The pluripotency transcription factor Krüppel-like factor 4 is strongly expressed in intratubular germ cell neoplasia unclassified and seminoma
Mol Hum Reprod, 15 (8), 479-88
PubMed 19505997 -
Functional glutathione S-transferase genotypes among testicular germ cell tumor survivors: associations with primary and post-chemotherapy tumor histology
Pharmacogenet Genomics, 19 (10), 751-9
PubMed 19741569 -
Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
J Cell Sci, 122 (Pt 21), 3883-93
PubMed 19808888 -
Tumor spreading to the contralateral ovary in bilateral ovarian carcinoma is a late event in clonal evolution
J Oncol, 2010, 646340
PubMed 19759843 -
Reverse painting of microdissected chromosome 19 markers in ovarian carcinoma identifies a complex rearrangement map
Genes Chromosomes Cancer, 48 (2), 184-93
PubMed 18973136 -
Casein haplotypes and their association with milk production traits in Norwegian Red cattle
Genet Sel Evol, 41, 24
PubMed 19284706 -
Large scale genomic instability as an additive prognostic marker in early prostate cancer
Cell Oncol, 31 (4), 251-9
PubMed 19633362 -
Transcriptional responses of Bacillus subtillis and thuringiensis to antibiotics and anti-tumour drugs
Int J Mol Med, 23 (1), 33-9
PubMed 19082504 -
Interplay between PKC and the MAP kinase pathway in Connexin43 phosphorylation and inhibition of gap junction intercellular communication
Biochem Biophys Res Commun, 382 (1), 41-5
PubMed 19258009 -
A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis
Mol Cancer, 8, 5
PubMed 19152679
Publications 2008
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RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1A
Neoplasia, 10 (7), 680-6, 2 p following 686
PubMed 18592002 -
Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers
Mol Cancer, 7, 94
PubMed 19117505 -
Protease-dependent fractional mass and peptide properties
Eur J Mass Spectrom (Chichester, Eng), 14 (5), 311-7
PubMed 19023148 -
Blind search for post-translational modifications and amino acid substitutions using peptide mass fingerprints from two proteases
BMC Res Notes, 1, 130
PubMed 19099572 -
Mandated lowering of toxicants in cigarette smoke: a description of the World Health Organization TobReg proposal
Tob Control, 17 (2), 132-41
PubMed 18375736 -
Novel mutations of the suppressor gene PTEN in colorectal carcinomas stratified by microsatellite instability- and TP53 mutation- status
Hum Mutat, 29 (11), E252-62
PubMed 18781614 -
Risk assessment of dietary exposures to compounds that are genotoxic and carcinogenic--an overview
Toxicol Lett, 180 (2), 110-7
PubMed 18584977 -
MassSorter: peptide mass fingerprinting data analysis
Methods Mol Biol, 484, 345-59
PubMed 18592191 -
The metastasis-associated protein S100A4 exists in several charged variants suggesting the presence of posttranslational modifications
BMC Cancer, 8, 172
PubMed 18554396 -
Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues
Genome Biol, 9 (9), R139
PubMed 18803840 -
Hypermethylated MAL gene - a silent marker of early colon tumorigenesis
J Transl Med, 6, 13
PubMed 18346269 -
The benzene metabolite trans,trans-muconaldehyde blocks gap junction intercellular communication by cross-linking connexin43
Toxicol Appl Pharmacol, 232 (3), 463-8
PubMed 18723040 -
Expression profiling of microRNAs in cancer cells: technical considerations
Methods Mol Biol, 439, 179-90
PubMed 18370103 -
The detergent resistance of Connexin43 is lost upon TPA or EGF treatment and is an early step in gap junction endocytosis
Biochem Biophys Res Commun, 373 (4), 597-601
PubMed 18601906
Publications 2007
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Improved gene expression signature of testicular carcinoma in situ
Int J Androl, 30 (4), 292-302; discussion 303
PubMed 17488342 -
Gene expression analysis in blood cells in response to unmodified and 2'-modified siRNAs reveals TLR-dependent and independent effects
J Mol Biol, 365 (1), 90-108
PubMed 17054988 -
Protein arrays: a versatile toolbox for target identification and monitoring of patient immune responses
Methods Mol Biol, 360, 335-48
PubMed 17172738 -
Mapping of oxidative stress responses of human tumor cells following photodynamic therapy using hexaminolevulinate
BMC Genomics, 8, 273
PubMed 17692132 -
Evolutionary selection pressure and family relationships among connexin genes
Biol Chem, 388 (3), 253-64
PubMed 17338632 -
Ovarian dysgerminomas are characterised by frequent KIT mutations and abundant expression of pluripotency markers
Mol Cancer, 6, 12
PubMed 17274819 -
Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses
Mol Cancer, 6, 2
PubMed 17201907 -
Ubiquitination of gap junction proteins
J Membr Biol, 217 (1-3), 43-51
PubMed 17657522 -
DNA hypermethylation of MAL: a promising diagnostic biomarker for colorectal tumors
Gastroenterology, 132 (4), 1631-2; author reply 1632
PubMed 17408629 -
The epigenome of testicular germ cell tumors
APMIS, 115 (10), 1147-60
PubMed 18042148 -
Association between long-term neuro-toxicities in testicular cancer survivors and polymorphisms in glutathione-s-transferase-P1 and -M1, a retrospective cross sectional study
J Transl Med, 5, 70
PubMed 18162130 -
Cisplatin-induced long-term hearing impairment is associated with specific glutathione s-transferase genotypes in testicular cancer survivors
J Clin Oncol, 25 (6), 708-14
PubMed 17228018 -
Slip slidin' away: a duodecennial review of targeted genes in mismatch repair deficient colorectal cancer
Crit Rev Oncog, 13 (3), 229-57
PubMed 18298386 -
Suppression of immunostimulatory siRNA-driven innate immune activation by 2'-modified RNAs
Biochem Biophys Res Commun, 361 (1), 122-6
PubMed 17658482 -
Alternative splicing in cancer: noise, functional, or systematic?
Int J Biochem Cell Biol, 39 (7-8), 1432-49
PubMed 17416541 -
The EPH receptor Bs (EPHBs) promoters are unmethylated in colon and ovarian cancers
Epigenetics, 2 (4), 237-43
PubMed 18281782 -
DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets
Mol Cancer, 6, 45
PubMed 17623056
Publications 2006
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MassSorter: a tool for administrating and analyzing data from mass spectrometry experiments on proteins with known amino acid sequences
BMC Bioinformatics, 7, 42
PubMed 16438723 -
The vertebrate connexin family
Cell Mol Life Sci, 63 (10), 1125-40
PubMed 16568237 -
The order of genetic events associated with colorectal cancer progression inferred from meta-analysis of copy number changes
Genes Chromosomes Cancer, 45 (1), 31-41
PubMed 16145679 -
Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study
Ann Oncol, 17 (5), 842-7
PubMed 16524972 -
TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming
Cancer Res, 66 (21), 10242-6
PubMed 17079440 -
Endocytic processing of connexin43 gap junctions: a morphological study
Biochem J, 393 (Pt 1), 59-67
PubMed 16162097 -
Downregulation of gap junctions in cancer cells
Crit Rev Oncog, 12 (3-4), 225-56
PubMed 17425504 -
ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis
Cell Oncol, 28 (5-6), 259-72
PubMed 17167179 -
Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN-1)
J Pathol, 210 (4), 441-9
PubMed 17029216 -
To the Readers and Future Authors of Critical Reviews in Oncogenesis
Critical Reviews in Oncogenesis, 12 (1-2), 1-2
PublikaID 27 -
Transcriptome changes in a colon adenocarcinoma cell line in response to photochemical treatment as used in photochemical internalisation (PCI)
FEBS Lett, 580 (24), 5739-46
PubMed 17007842 -
Statistical dissection of genetic pathways involved in prostate carcinogenesis
Genes Chromosomes Cancer, 45 (2), 154-63
PubMed 16235241 -
Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas
Mol Cancer, 5, 33
PubMed 16952311 -
8q gain is an independent predictor of poor survival in diagnostic needle biopsies from prostate cancer suspects
Clin Cancer Res, 12 (13), 3961-70
PubMed 16818693 -
Novel genomic aberrations in testicular germ cell tumors by array-CGH, and associated gene expression changes
Cell Oncol, 28 (5-6), 315-26
PubMed 17167184 -
Identification of a novel amplicon at distal 17q containing the BIRC5/SURVIVIN gene in malignant peripheral nerve sheath tumours
J Pathol, 209 (4), 492-500
PubMed 16721726 -
Precursor lesions in testis and dysgenetic gonads
Hum Pathol, 37 (6), 773; author reply 774
PubMed 16733221




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