Publications

Publications published since 2006 or in press from OUS - Department of Cancer Prevention

143 publications found

Publications in press

1. Chung CC, Kanetsky PA, Wang Z, Hildebrandt MA, Koster R, Skotheim RI, Kratz CP, Turnbull C, Cortessis VK, Bakken AC, Bishop DT, Cook MB, Erickson RL, Fosså SD, Jacobs KB, Korde LA, Kraggerud SM, Lothe RA, Loud JT, Rahman N, Skinner EC, Thomas DC, Wu X, Yeager M, Schumacher FR et al.
   Meta-analysis identifies four new loci associated with testicular germ cell tumor
   Nat Genet (in press)
   PubMed 23666239
2. Kraggerud SM, Hoei-Hansen CE, Alagaratnam S, Skotheim RI, Abeler VM, Rajpert-De Meyts E, Lothe RA
   Molecular Characteristics of Malignant Ovarian Germ Cell Tumors and Comparison With Testicular Counterparts: Implications for Pathogenesis
   Endocr Rev (in press)
   PubMed 23575763
3. Schumacher FR, Wang Z, Skotheim RI, Koster R, Chung CC, Hildebrandt MA, Kratz CP, Bakken AC, Timothy Bishop D, Cook MB, Erickson RL, Fosså SD, Greene MH, Jacobs KB, Kanetsky PA, Kolonel LN, Loud JT, Korde LA, Le Marchand L, Pablo Lewinger J, Lothe RA, Pike MC, Rahman N, Rubertone MV, Schwartz SM et al.
   Testicular germ cell tumor susceptibility associated with the UCK2 locus on chromosome 1q23
   Hum Mol Genet (in press)
   PubMed 23462292

Publications 2013

1. Alagaratnam S, Harrison N, Bakken AC, Hoff AM, Jones M, Sveen A, Moore HD, Andrews PW, Lothe RA, Skotheim RI (2013)
   Transforming pluripotency: an exon-level study of malignancy-specific transcripts in human embryonal carcinoma and embryonic stem cells
   Stem Cells Dev, 22 (7), 1136-46
   PubMed 23137282
2. Eide PW, Cekaite L, Danielsen SA, Eilertsen IA, Kjenseth A, Fykerud TA, Ågesen TH, Bruun J, Rivedal E, Lothe RA, Leithe E (2013)
   NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway
   Cell Signal, 25 (1), 12-8
   PubMed 22974840
3. Kolberg M, Høland M, Agesen TH, Brekke HR, Liestøl K, Hall KS, Mertens F, Picci P, Smeland S, Lothe RA (2013)
   Survival meta-analyses for >1800 malignant peripheral nerve sheath tumor patients with and without neurofibromatosis type 1
   Neuro Oncol, 15 (2), 135-47
   PubMed 23161774
4. Lindberg J, Mills IG, Klevebring D, Liu W, Neiman M, Xu J, Wikström P, Wiklund P, Wiklund F, Egevad L, Grönberg H (2013)
   The mitochondrial and autosomal mutation landscapes of prostate cancer
   Eur Urol, 63 (4), 702-8
   PubMed 23265383
5. Lobert VH, Bruun J, Abrahamsen H, Lothe RA, Stenmark H, Kolberg M, Campsteijn C (2013)
   Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene ?-catenin
   EMBO Rep, 14 (1), 10-1
   PubMed 23229585
6. Merok MA, Ahlquist T, Røyrvik EC, Tufteland KF, Hektoen M, Sjo OH, Mala T, Svindland A, Lothe RA, Nesbakken A (2013)
   Microsatellite instability has a positive prognostic impact on stage II colorectal cancer after complete resection: results from a large, consecutive Norwegian series
   Ann Oncol, 24 (5), 1274-82
   PubMed 23235802
7. Mesquita B, Lopes P, Rodrigues A, Pereira D, Afonso M, Leal C, Henrique R, Lind GE, Jerónimo C, Lothe RA, Teixeira MR (2013)
   Frequent copy number gains at 1q21 and 1q32 are associated with overexpression of the ETS transcription factors ETV3 and ELF3 in breast cancer irrespective of molecular subtypes
   Breast Cancer Res Treat, 138 (1), 37-45
   PubMed 23329352
8. Sharma NL, Massie CE, Ramos-Montoya A, Zecchini V, Scott HE, Lamb AD, MacArthur S, Stark R, Warren AY, Mills IG, Neal DE (2013)
   The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man
   Cancer Cell, 23 (1), 35-47
   PubMed 23260764

Publications 2012

1. Agesen TH, Sveen A, Merok MA, Lind GE, Nesbakken A, Skotheim RI, Lothe RA (2012)
   ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis
   Gut, 61 (11), 1560-7
   PubMed 22213796
2. Ahmed D, Danielsen SA, Aagesen TH, Bretthauer M, Thiis-Evensen E, Hoff G, Rognum TO, Nesbakken A, Lothe RA, Lind GE (2012)
   A tissue-based comparative effectiveness analysis of biomarkers for early detection of colorectal tumors
   Clin Transl Gastroenterol, 3, e27
   PubMed 23324654
3. Andresen K, Boberg KM, Vedeld HM, Honne H, Hektoen M, Wadsworth CA, Clausen OP, Karlsen TH, Foss A, Mathisen O, Schrumpf E, Lothe RA, Lind GE (2012)
   Novel target genes and a valid biomarker panel identified for cholangiocarcinoma
   Epigenetics, 7 (11), 1249-57
   PubMed 22983262
4. Brabrand S, Fosså SD, Cvancarova M, Axcrona U, Lehne G (2012)
   Probability of metachronous testicular cancer in patients with biopsy-proven intratubular germ cell neoplasia depends on first-time treatment of germ cell cancer
   J Clin Oncol, 30 (32), 4004-10
   PubMed 23071246
5. Camões MJ, Paulo P, Ribeiro FR, Barros-Silva JD, Almeida M, Costa VL, Cerveira N, Skotheim RI, Lothe RA, Henrique R, Jerónimo C, Teixeira MR (2012)
   Potential downstream target genes of aberrant ETS transcription factors are differentially affected in Ewing's sarcoma and prostate carcinoma
   PLoS One, 7 (11), e49819
   PubMed 23185447
6. Cekaite L, Rantala JK, Bruun J, Guriby M, Agesen TH, Danielsen SA, Lind GE, Nesbakken A, Kallioniemi O, Lothe RA, Skotheim RI (2012)
   MiR-9, -31, and -182 deregulation promote proliferation and tumor cell survival in colon cancer
   Neoplasia, 14 (9), 868-79
   PubMed 23019418
7. Celestino R, Sigstad E, Løvf M, Thomassen GO, Grøholt KK, Jørgensen LH, Berner A, Castro P, Lothe RA, Bjøro T, Sobrinho-Simões M, Soares P, Skotheim RI (2012)
   Survey of 548 oncogenic fusion transcripts in thyroid tumors supports the importance of the already established thyroid fusions genes
   Genes Chromosomes Cancer, 51 (12), 1154-64
   PubMed 22961909
8. Fykerud TA, Kjenseth A, Schink KO, Sirnes S, Bruun J, Omori Y, Brech A, Rivedal E, Leithe E (2012)
   Smad ubiquitination regulatory factor-2 controls gap junction intercellular communication by modulating endocytosis and degradation of connexin43
   J Cell Sci, 125 (Pt 17), 3966-76
   PubMed 22623726
9. Grisanzio C, Werner L, Takeda D, Awoyemi BC, Pomerantz MM, Yamada H, Sooriakumaran P, Robinson BD, Leung R, Schinzel AC, Mills I, Ross-Adams H, Neal DE, Kido M, Yamamoto T, Petrozziello G, Stack EC, Lis R, Kantoff PW, Loda M, Sartor O, Egawa S, Tewari AK, Hahn WC, Freedman ML (2012)
   Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis
   Proc Natl Acad Sci U S A, 109 (28), 11252-7
   PubMed 22730461
10. Hart LS, Cunningham JT, Datta T, Dey S, Tameire F, Lehman SL, Qiu B, Zhang H, Cerniglia G, Bi M, Li Y, Gao Y, Liu H, Li C, Maity A, Thomas-Tikhonenko A, Perl AE, Koong A, Fuchs SY, Diehl JA, Mills IG, Ruggero D, Koumenis C (2012)
    ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth
    J Clin Invest, 122 (12), 4621-34
    PubMed 23143306
11. Håvik AB, Brandal P, Honne H, Dahlback HS, Scheie D, Hektoen M, Meling TR, Helseth E, Heim S, Lothe RA, Lind GE (2012)
    MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR
    J Transl Med, 10, 36
    PubMed 22390413
12. Kjenseth A, Fykerud TA, Sirnes S, Bruun J, Yohannes Z, Kolberg M, Omori Y, Rivedal E, Leithe E (2012)
    The gap junction channel protein connexin 43 is covalently modified and regulated by SUMOylation
    J Biol Chem, 287 (19), 15851-61
    PubMed 22411987
13. Leithe E, Sirnes S, Fykerud T, Kjenseth A, Rivedal E (2012)
    Endocytosis and post-endocytic sorting of connexins
    Biochim Biophys Acta, 1818 (8), 1870-9
    PubMed 21996040
14. Lind GE, Ahmed D, Lothe RA (2012)
    Vimentin in upper gastrointestinal pathologies--letter
    Cancer Epidemiol Biomarkers Prev, 21 (10), 1889; author reply 1890
    PubMed 22929079
15. Matheu A, Collado M, Wise C, Manterola L, Cekaite L, Tye AJ, Canamero M, Bujanda L, Schedl A, Cheah KS, Skotheim RI, Lothe RA, López de Munain A, Briscoe J, Serrano M, Lovell-Badge R (2012)
    Oncogenicity of the developmental transcription factor Sox9
    Cancer Res, 72 (5), 1301-15
    PubMed 22246670
16. Mills IG (2012)
    Nuclear translocation and functions of growth factor receptors
    Semin Cell Dev Biol, 23 (2), 165-71
    PubMed 21930229
17. Nordgård O, Oltedal S, Aasprong OG, Søreide JA, Søreide K, Tjensvoll K, Gilje B, Heikkilä R, Guriby M, Lothe RA, Smaaland R, Kørner H (2012)
    Prognostic relevance of occult metastases detected by cytokeratin 20 and mucin 2 mRNA levels in sentinel lymph nodes from colon cancer patients
    Ann Surg Oncol, 19 (12), 3719-26
    PubMed 22752373
18. Nyquist KB, Panagopoulos I, Thorsen J, Haugom L, Gorunova L, Bjerkehagen B, Fosså A, Guriby M, Nome T, Lothe RA, Skotheim RI, Heim S, Micci F (2012)
    Whole-transcriptome sequencing identifies novel IRF2BP2-CDX1 fusion gene brought about by translocation t(1;5)(q42;q32) in mesenchymal chondrosarcoma
    PLoS One, 7 (11), e49705
    PubMed 23185413
19. Paulo P, Barros-Silva JD, Ribeiro FR, Ramalho-Carvalho J, Jerónimo C, Henrique R, Lind GE, Skotheim RI, Lothe RA, Teixeira MR (2012)
    FLI1 is a novel ETS transcription factor involved in gene fusions in prostate cancer
    Genes Chromosomes Cancer, 51 (3), 240-9
    PubMed 22081504
20. Paulo P, Ribeiro FR, Santos J, Mesquita D, Almeida M, Barros-Silva JD, Itkonen H, Henrique R, Jerónimo C, Sveen A, Mills IG, Skotheim RI, Lothe RA, Teixeira MR (2012)
    Molecular subtyping of primary prostate cancer reveals specific and shared target genes of different ETS rearrangements
    Neoplasia, 14 (7), 600-11
    PubMed 22904677
21. Sandvik GK, Tomter AB, Bergan J, Zoppellaro G, Barra AL, Røhr AK, Kolberg M, Ellefsen S, Andersson KK, Nilsson GE (2012)
    Studies of ribonucleotide reductase in crucian carp-an oxygen dependent enzyme in an anoxia tolerant vertebrate
    PLoS One, 7 (8), e42784
    PubMed 22916159
22. Sirnes S, Bruun J, Kolberg M, Kjenseth A, Lind GE, Svindland A, Brech A, Nesbakken A, Lothe RA, Leithe E, Rivedal E (2012)
    Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
    Int J Cancer, 131 (3), 570-81
    PubMed 21866551
23. Sjo OH, Merok MA, Svindland A, Nesbakken A (2012)
    Prognostic impact of lymph node harvest and lymph node ratio in patients with colon cancer
    Dis Colon Rectum, 55 (3), 307-15
    PubMed 22469798
24. Skotheim RI, Meza-Zepeda LA, Hovig E, Lønning PE, Lothe RA, Myklebost O (2012)
    [Genome sequencing for personalized cancer treatment]
    Tidsskr Nor Laegeforen, 132 (21), 2406-8
    PubMed 23160594
25. Sveen A, Bakken AC, Ågesen TH, Lind GE, Nesbakken A, Nordgård O, Brackmann S, Rognum TO, Lothe RA, Skotheim RI (2012)
    The exon-level biomarker SLC39A14 has organ-confined cancer-specificity in colorectal cancer
    Int J Cancer, 131 (6), 1479-85
    PubMed 22173985
26. Sveen A, Ågesen TH, Nesbakken A, Meling GI, Rognum TO, Liestøl K, Skotheim RI, Lothe RA (2012)
    ColoGuidePro: a prognostic 7-gene expression signature for stage III colorectal cancer patients
    Clin Cancer Res, 18 (21), 6001-10
    PubMed 22991413

Publications 2011

1. Ahmed D, Lothe RA, Rivedal E, Lind GE (2011)
   Quantitative validation of GJC1 promoter hypermethylation in benign and malignant colorectal tumors
   Endocr Relat Cancer, 18 (6), C31-4
   PubMed 21868474
2. Alagaratnam S, Lind GE, Kraggerud SM, Lothe RA, Skotheim RI (2011)
   The testicular germ cell tumour transcriptome
   Int J Androl, 34 (4 Pt 2), e133-50; discussion e150-1
   PubMed 21651573
3. Berg M, Søreide K (2011)
   Genetic and epigenetic traits as biomarkers in colorectal cancer
   Int J Mol Sci, 12 (12), 9426-39
   PubMed 22272141
4. Berg M, Søreide K (2011)
   Prevention: will an aspirin a day keep the colorectal cancer away?
   Nat Rev Clin Oncol, 8 (3), 130-1
   PubMed 21200396
5. Berge G, Costea DE, Berg M, Rasmussen H, Grotterød I, Lothe RA, Mælandsmo GM, Flatmark K (2011)
   Coexpression and nuclear colocalization of metastasis-promoting protein S100A4 and p53 without mutual regulation in colorectal carcinoma
   Amino Acids, 41 (4), 875-84
   PubMed 20191297
6. Boberg KM, Lind GE (2011)
   Primary sclerosing cholangitis and malignancy
   Best Pract Res Clin Gastroenterol, 25 (6), 753-64
   PubMed 22117640
7. Brabrand S, Fosså SD, Cvancarova M, Lehne G (2011)
   Androgen substitution with testosterone undecanoate in survivors of bilateral testicular cancer requires individually-adjusted injection intervals
   BJU Int, 107 (7), 1080-7
   PubMed 20825398
8. Costa VL, Henrique R, Danielsen SA, Eknaes M, Patrício P, Morais A, Oliveira J, Lothe RA, Teixeira MR, Lind GE, Jerónimo C (2011)
   TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers
   Epigenetics, 6 (9), 1120-30
   PubMed 21847011
9. Danielsen SA, Cekaite L, Ågesen TH, Sveen A, Nesbakken A, Thiis-Evensen E, Skotheim RI, Lind GE, Lothe RA (2011)
   Phospholipase C isozymes are deregulated in colorectal cancer--insights gained from gene set enrichment analysis of the transcriptome
   PLoS One, 6 (9), e24419
   PubMed 21909432
10. Johansen D, Cruciani V, Sundset R, Ytrehus K, Mikalsen SO (2011)
    Ischemia induces closure of gap junctional channels and opening of hemichannels in heart-derived cells and tissue
    Cell Physiol Biochem, 28 (1), 103-14
    PubMed 21865853
11. Lind GE, Danielsen SA, Ahlquist T, Merok MA, Andresen K, Skotheim RI, Hektoen M, Rognum TO, Meling GI, Hoff G, Bretthauer M, Thiis-Evensen E, Nesbakken A, Lothe RA (2011)
    Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas
    Mol Cancer, 10, 85
    PubMed 21777459
12. Lind GE, Raiborg C, Danielsen SA, Rognum TO, Thiis-Evensen E, Hoff G, Nesbakken A, Stenmark H, Lothe RA (2011)
    SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
    Oncogene, 30 (37), 3967-78
    PubMed 21499309
13. Løvf M, Thomassen GO, Bakken AC, Celestino R, Fioretos T, Lind GE, Lothe RA, Skotheim RI (2011)
    Fusion gene microarray reveals cancer type-specificity among fusion genes
    Genes Chromosomes Cancer, 50 (5), 348-57
    PubMed 21305644
14. Malerød L, Pedersen NM, Sem Wegner CE, Lobert VH, Leithe E, Brech A, Rivedal E, Liestøl K, Stenmark H (2011)
    Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting
    Traffic, 12 (9), 1211-26
    PubMed 21564451
15. Mollerup S, Hofgaard JP, Braunstein TH, Kjenseth A, Leithe E, Rivedal E, Holstein-Rathlou NH, Nielsen MS (2011)
    Norepinephrine inhibits intercellular coupling in rat cardiomyocytes by ubiquitination of connexin43 gap junctions
    Cell Commun Adhes, 18 (4), 57-65
    PubMed 21936631
16. Ohnstad HO, Paulsen EB, Noordhuis P, Berg M, Lothe RA, Vassilev LT, Myklebost O (2011)
    MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines
    BMC Cancer, 11, 211:1-11
    PubMed 21624110
17. Ribeiro FR, Paulo P, Costa VL, Barros-Silva JD, Ramalho-Carvalho J, Jerónimo C, Henrique R, Lind GE, Skotheim RI, Lothe RA, Teixeira MR (2011)
    Cysteine-rich secretory protein-3 (CRISP3) is strongly up-regulated in prostate carcinomas with the TMPRSS2-ERG fusion gene
    PLoS One, 6 (7), e22317
    PubMed 21814574
18. Sagona AP, Nezis IP, Bache KG, Haglund K, Bakken AC, Skotheim RI, Stenmark H (2011)
    A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
    PLoS One, 6 (3), e17086
    PubMed 21455500
19. Sirnes S, Honne H, Ahmed D, Danielsen SA, Rognum TO, Meling GI, Leithe E, Rivedal E, Lothe RA, Lind GE (2011)
    DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer
    Epigenetics, 6 (5), 602-9
    PubMed 21406965
20. Sjo OH, Berg M, Merok MA, Kolberg M, Svindland A, Lothe RA, Nesbakken A (2011)
    Peritoneal carcinomatosis of colon cancer origin: highest incidence in women and in patients with right-sided tumors
    J Surg Oncol, 104 (7), 792-7
    PubMed 21547915
21. Soreide K, Berg M, Skudal BS, Nedrebo BS (2011)
    Advances in the Understanding and Treatment of Colorectal Cancer
    Discov. Med., 66, 393-404
22. Sveen A, Agesen TH, Nesbakken A, Rognum TO, Lothe RA, Skotheim RI (2011)
    Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival
    Genome Med, 3 (5), 32
    PubMed 21619627
23. Ågesen TH, Berg M, Clancy T, Thiis-Evensen E, Cekaite L, Lind GE, Nesland JM, Bakka A, Mala T, Hauss HJ, Fetveit T, Vatn MH, Hovig E, Nesbakken A, Lothe RA, Skotheim RI (2011)
    CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer
    Genes Immun, 12 (8), 653-62
    PubMed 21716316

Publications 2010

1. Berg M, Agesen TH, Thiis-Evensen E, INFAC-study group, Merok MA, Teixeira MR, Vatn MH, Nesbakken A, Skotheim RI, Lothe RA (2010)
   Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci
   Mol Cancer, 9, 100
   PubMed 20459617
2. Berg M, Danielsen SA, Ahlquist T, Merok MA, Ågesen TH, Vatn MH, Mala T, Sjo OH, Bakka A, Moberg I, Fetveit T, Mathisen Ø, Husby A, Sandvik O, Nesbakken A, Thiis-Evensen E, Lothe RA (2010)
   DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset
   PLoS One, 5 (11), e13978
   PubMed 21103049
3. Brekke HR, Ribeiro FR, Kolberg M, Agesen TH, Lind GE, Eknaes M, Hall KS, Bjerkehagen B, van den Berg E, Teixeira MR, Mandahl N, Smeland S, Mertens F, Skotheim RI, Lothe RA (2010)
   Genomic changes in chromosomes 10, 16, and X in malignant peripheral nerve sheath tumors identify a high-risk patient group
   J Clin Oncol, 28 (9), 1573-82
   PubMed 20159821
4. Burum-Auensen E, Skotheim RI, Schjølberg AR, Røislien J, Lothe RA, Clausen OP (2010)
   Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors
   J Carcinog, 9, 1
   PubMed 20411023
5. Cekaite L, Clancy T, Sioud M (2010)
   Increased miR-21 expression during human monocyte differentiation into DCs
   Front Biosci (Elite Ed), 2, 818-28
   PubMed 20515755
6. Costa VL, Henrique R, Danielsen SA, Duarte-Pereira S, Eknaes M, Skotheim RI, Rodrigues A, Magalhães JS, Oliveira J, Lothe RA, Teixeira MR, Jerónimo C, Lind GE (2010)
   Three epigenetic biomarkers, GDF15, TMEFF2, and VIM, accurately predict bladder cancer from DNA-based analyses of urine samples
   Clin Cancer Res, 16 (23), 5842-51
   PubMed 20975101
7. Kjenseth A, Fykerud T, Rivedal E, Leithe E (2010)
   Regulation of gap junction intercellular communication by the ubiquitin system
   Cell Signal, 22 (9), 1267-73
   PubMed 20206687
8. Knævelsrud H, Ahlquist T, Merok MA, Nesbakken A, Stenmark H, Lothe RA, Simonsen A (2010)
   UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
   Autophagy, 6 (7), 863-70
   PubMed 20724836
9. Leithe E, Kjenseth A, Bruun J, Sirnes S, Rivedal E (2010)
   Inhibition of connexin 43 gap junction channels by the endocrine disruptor ioxynil
   Toxicol Appl Pharmacol, 247 (1), 10-7
   PubMed 20510257
10. Micci F, Haugom L, Ahlquist T, Andersen HK, Abeler VM, Davidson B, Trope CG, Lothe RA, Heim S (2010)
    Genomic aberrations in borderline ovarian tumors
    J Transl Med, 8, 21
    PubMed 20184781
11. Micci F, Skotheim RI, Haugom L, Weimer J, Eibak AM, Abeler VM, Trope CG, Arnold N, Lothe RA, Heim S (2010)
    Array-CGH analysis of microdissected chromosome 19 markers in ovarian carcinoma identifies candidate target genes
    Genes Chromosomes Cancer, 49 (11), 1046-53
    PubMed 20725991
12. Pinheiro M, Ahlquist T, Danielsen SA, Lind GE, Veiga I, Pinto C, Costa V, Afonso L, Sousa O, Fragoso M, Santos L, Henrique R, Lopes P, Lopes C, Lothe RA, Teixeira MR (2010)
    Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin
    BMC Cancer, 10, 587
    PubMed 20979647
13. Rivedal E, Witz G, Leithe E (2010)
    Gap junction intercellular communication and benzene toxicity
    Chem Biol Interact, 184 (1-2), 229-32
    PubMed 19932693
14. Sagona AP, Nezis IP, Pedersen NM, Liestøl K, Poulton J, Rusten TE, Skotheim RI, Raiborg C, Stenmark H (2010)
    PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
    Nat Cell Biol, 12 (4), 362-71
    PubMed 20208530
15. Sioud M, Cekaite L (2010)
    Profiling of miRNA expression and prediction of target genes
    Methods Mol Biol, 629, 257-71
    PubMed 20387154
16. Tekpli X, Rivedal E, Gorria M, Landvik NE, Rissel M, Dimanche-Boitrel MT, Baffet G, Holme JA, Lagadic-Gossmann D (2010)
    The B[a]P-increased intercellular communication via translocation of connexin-43 into gap junctions reduces apoptosis
    Toxicol Appl Pharmacol, 242 (2), 231-40
    PubMed 19874837
17. Thomassen GO, Weel-Sneve R, Rowe AD, Booth JA, Lindvall JM, Lagesen K, Kristiansen KI, Bjørås M, Rognes T (2010)
    Tiling array analysis of UV treated Escherichia coli predicts novel differentially expressed small peptides
    PLoS One, 5 (12), e15356
    PubMed 21203457
18. Zwierzina H, Bardelli A, Ciardiello F, Gariboldi M, Håkansson L, Lambrechts D, Lind GE, Loeffler-Ragg J, Schmoll H, Siena S, Tabernero J, Van Cutsem E (2010)
    Molecularly targeted therapies for colorectal cancer: Strategies for implementing translational research in clinical trials
    Curr Opin Mol Ther, 12 (6), 703-11
    PubMed 21154162

Publications 2009

1. Ahlquist T (2009)
   New doctorial cancer research:novel genetic and epigenetic alterations in colorectal tumors and their potential as biomarkers
   Crit Rev Oncog, 15 (1), 81-3
   PubMed 20092436
2. Alagaratnam S, Hardy JR, Lothe RA, Skotheim RI, Byrne JA (2009)
   TPD52, a candidate gene from genomic studies, is overexpressed in testicular germ cell tumours
   Mol Cell Endocrinol, 306 (1-2), 75-80
   PubMed 19041365
3. Bottillo I, Ahlquist T, Brekke H, Danielsen SA, van den Berg E, Mertens F, Lothe RA, Dallapiccola B (2009)
   Germline and somatic NF1 mutations in sporadic and NF1-associated malignant peripheral nerve sheath tumours
   J Pathol, 217 (5), 693-701
   PubMed 19142971
4. Brech A, Ahlquist T, Lothe RA, Stenmark H (2009)
   Autophagy in tumour suppression and promotion
   Mol Oncol, 3 (4), 366-75
   PubMed 19559660
5. Brekke HR, Kolberg M, Skotheim RI, Hall KS, Bjerkehagen B, Risberg B, Domanski HA, Mandahl N, Liestøl K, Smeland S, Danielsen HE, Mertens F, Lothe RA (2009)
   Identification of p53 as a strong predictor of survival for patients with malignant peripheral nerve sheath tumors
   Neuro Oncol, 11 (5), 514-28
   PubMed 19182148
6. Cekaite L, Hovig E, Sioud M (2009)
   Monitoring B cell response to immunoselected phage-displayed peptides by microarrays
   Methods Mol Biol, 524, 273-85
   PubMed 19377952
7. Danielsen SA, Lind GE, Biornslett M, Meling GI, Rognum TO, Heim S, Lothe RA (2009)
   Novel Mutations of the Suppressor Gene PTEN in Colorectal Carcinomas Stratified by Microsatellite Instability- and TP53 Mutation- Status (vol 29, pg E252, 2008)
   Hum. Mutat., 30 (6), 1023
8. Godmann M, Gashaw I, Eildermann K, Schweyer S, Bergmann M, Skotheim RI, Behr R (2009)
   The pluripotency transcription factor Krüppel-like factor 4 is strongly expressed in intratubular germ cell neoplasia unclassified and seminoma
   Mol Hum Reprod, 15 (8), 479-88
   PubMed 19505997
9. Kraggerud SM, Oldenburg J, Alnaes GI, Berg M, Kristensen VN, Fossa SD, Lothe RA (2009)
   Functional glutathione S-transferase genotypes among testicular germ cell tumor survivors: associations with primary and post-chemotherapy tumor histology
   Pharmacogenet Genomics, 19 (10), 751-9
   PubMed 19741569
10. Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, Rivedal E (2009)
    Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
    J Cell Sci, 122 (Pt 21), 3883-93
    PubMed 19808888
11. Micci F, Haugom L, Ahlquist T, Abeler VM, Trope CG, Lothe RA, Heim S (2009)
    Tumor spreading to the contralateral ovary in bilateral ovarian carcinoma is a late event in clonal evolution
    J Oncol, 2010, 646340
    PubMed 19759843
12. Micci F, Weimer J, Haugom L, Skotheim RI, Grunewald R, Abeler VM, Silins I, Lothe RA, Trope CG, Arnold N, Heim S (2009)
    Reverse painting of microdissected chromosome 19 markers in ovarian carcinoma identifies a complex rearrangement map
    Genes Chromosomes Cancer, 48 (2), 184-93
    PubMed 18973136
13. Nilsen H, Olsen HG, Hayes B, Sehested E, Svendsen M, Nome T, Meuwissen T, Lien S (2009)
    Casein haplotypes and their association with milk production traits in Norwegian Red cattle
    Genet Sel Evol, 41, 24
    PubMed 19284706
14. Pretorius ME, Waehre H, Abeler VM, Davidson B, Vlatkovic L, Lothe RA, Giercksky KE, Danielsen HE (2009)
    Large scale genomic instability as an additive prognostic marker in early prostate cancer
    Cell Oncol, 31 (4), 251-9
    PubMed 19633362
15. Sioud M, Boudabous A, Cekaite L (2009)
    Transcriptional responses of Bacillus subtillis and thuringiensis to antibiotics and anti-tumour drugs
    Int J Mol Med, 23 (1), 33-9
    PubMed 19082504
16. Sirnes S, Kjenseth A, Leithe E, Rivedal E (2009)
    Interplay between PKC and the MAP kinase pathway in Connexin43 phosphorylation and inhibition of gap junction intercellular communication
    Biochem Biophys Res Commun, 382 (1), 41-5
    PubMed 19258009
17. Skotheim RI, Thomassen GO, Eken M, Lind GE, Micci F, Ribeiro FR, Cerveira N, Teixeira MR, Heim S, Rognes T, Lothe RA (2009)
    A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis
    Mol Cancer, 8, 5
    PubMed 19152679

Publications 2008

1. Ahlquist T, Bottillo I, Danielsen SA, Meling GI, Rognum TO, Lind GE, Dallapiccola B, Lothe RA (2008)
   RAS signaling in colorectal carcinomas through alteration of RAS, RAF, NF1, and/or RASSF1A
   Neoplasia, 10 (7), 680-6, 2 p following 686
   PubMed 18592002
2. Ahlquist T, Lind GE, Costa VL, Meling GI, Vatn M, Hoff GS, Rognum TO, Skotheim RI, Thiis-Evensen E, Lothe RA (2008)
   Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers
   Mol Cancer, 7, 94
   PubMed 19117505
3. Barsnes H, Eidhammer I, Cruciani V, Mikalsen SO (2008)
   Protease-dependent fractional mass and peptide properties
   Eur J Mass Spectrom (Chichester, Eng), 14 (5), 311-7
   PubMed 19023148
4. Barsnes H, Mikalsen SO, Eidhammer I (2008)
   Blind search for post-translational modifications and amino acid substitutions using peptide mass fingerprints from two proteases
   BMC Res Notes, 1, 130
   PubMed 19099572
5. Burns DM, Dybing E, Gray N, Hecht S, Anderson C, Sanner T, O'Connor R, Djordjevic M, Dresler C, Hainaut P, Jarvis M, Opperhuizen A, Straif K (2008)
   Mandated lowering of toxicants in cigarette smoke: a description of the World Health Organization TobReg proposal
   Tob Control, 17 (2), 132-41
   PubMed 18375736
6. Danielsen SA, Lind GE, Bjørnslett M, Meling GI, Rognum TO, Heim S, Lothe RA (2008)
   Novel mutations of the suppressor gene PTEN in colorectal carcinomas stratified by microsatellite instability- and TP53 mutation- status
   Hum Mutat, 29 (11), E252-62
   PubMed 18781614
7. Dybing E, O'Brien J, Renwick AG, Sanner T (2008)
   Risk assessment of dietary exposures to compounds that are genotoxic and carcinogenic--an overview
   Toxicol Lett, 180 (2), 110-7
   PubMed 18584977
8. Eidhammer I, Barsnes H, Mikalsen SO (2008)
   MassSorter: peptide mass fingerprinting data analysis
   Methods Mol Biol, 484, 345-59
   PubMed 18592191
9. Haugen MH, Flatmark K, Mikalsen SO, Malandsmo GM (2008)
   The metastasis-associated protein S100A4 exists in several charged variants suggesting the presence of posttranslational modifications
   BMC Cancer, 8, 172
   PubMed 18554396
10. Kilpinen S, Autio R, Ojala K, Iljin K, Bucher E, Sara H, Pisto T, Saarela M, Skotheim RI, Björkman M, Mpindi JP, Haapa-Paananen S, Vainio P, Edgren H, Wolf M, Astola J, Nees M, Hautaniemi S, Kallioniemi O (2008)
    Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues
    Genome Biol, 9 (9), R139
    PubMed 18803840
11. Lind GE, Ahlquist T, Kolberg M, Berg M, Eknaes M, Alonso MA, Kallioniemi A, Meling GI, Skotheim RI, Rognum TO, Thiis-Evensen E, Lothe RA (2008)
    Hypermethylated MAL gene - a silent marker of early colon tumorigenesis
    J Transl Med, 6, 13
    PubMed 18346269
12. Rivedal E, Leithe E (2008)
    The benzene metabolite trans,trans-muconaldehyde blocks gap junction intercellular communication by cross-linking connexin43
    Toxicol Appl Pharmacol, 232 (3), 463-8
    PubMed 18723040
13. Sioud M, Cekaite L (2008)
    Expression profiling of microRNAs in cancer cells: technical considerations
    Methods Mol Biol, 439, 179-90
    PubMed 18370103
14. Sirnes S, Leithe E, Rivedal E (2008)
    The detergent resistance of Connexin43 is lost upon TPA or EGF treatment and is an early step in gap junction endocytosis
    Biochem Biophys Res Commun, 373 (4), 597-601
    PubMed 18601906

Publications 2007

1. Almstrup K, Leffers H, Lothe RA, Skakkebaek NE, Sonne SB, Nielsen JE, Rajpert-De Meyts E, Skotheim RI (2007)
   Improved gene expression signature of testicular carcinoma in situ
   Int J Androl, 30 (4), 292-302; discussion 303
   PubMed 17488342
2. Cekaite L, Furset G, Hovig E, Sioud M (2007)
   Gene expression analysis in blood cells in response to unmodified and 2'-modified siRNAs reveals TLR-dependent and independent effects
   J Mol Biol, 365 (1), 90-108
   PubMed 17054988
3. Cekaite L, Hovig E, Sioud M (2007)
   Protein arrays: a versatile toolbox for target identification and monitoring of patient immune responses
   Methods Mol Biol, 360, 335-48
   PubMed 17172738
4. Cekaite L, Peng Q, Reiner A, Shahzidi S, Tveito S, Furre IE, Hovig E (2007)
   Mapping of oxidative stress responses of human tumor cells following photodynamic therapy using hexaminolevulinate
   BMC Genomics, 8, 273
   PubMed 17692132
5. Cruciani V, Mikalsen SO (2007)
   Evolutionary selection pressure and family relationships among connexin genes
   Biol Chem, 388 (3), 253-64
   PubMed 17338632
6. Hoei-Hansen CE, Kraggerud SM, Abeler VM, Kaern J, Rajpert-De Meyts E, Lothe RA (2007)
   Ovarian dysgerminomas are characterised by frequent KIT mutations and abundant expression of pluripotency markers
   Mol Cancer, 6, 12
   PubMed 17274819
7. Kleivi K, Lind GE, Diep CB, Meling GI, Brandal LT, Nesland JM, Myklebost O, Rognum TO, Giercksky KE, Skotheim RI, Lothe RA (2007)
   Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses
   Mol Cancer, 6, 2
   PubMed 17201907
8. Leithe E, Rivedal E (2007)
   Ubiquitination of gap junction proteins
   J Membr Biol, 217 (1-3), 43-51
   PubMed 17657522
9. Lind GE, Ahlquist T, Lothe RA (2007)
   DNA hypermethylation of MAL: a promising diagnostic biomarker for colorectal tumors
   Gastroenterology, 132 (4), 1631-2; author reply 1632
   PubMed 17408629
10. Lind GE, Skotheim RI, Lothe RA (2007)
    The epigenome of testicular germ cell tumors
    APMIS, 115 (10), 1147-60
    PubMed 18042148
11. Oldenburg J, Kraggerud SM, Brydøy M, Cvancarova M, Lothe RA, Fossa SD (2007)
    Association between long-term neuro-toxicities in testicular cancer survivors and polymorphisms in glutathione-s-transferase-P1 and -M1, a retrospective cross sectional study
    J Transl Med, 5, 70
    PubMed 18162130
12. Oldenburg J, Kraggerud SM, Cvancarova M, Lothe RA, Fossa SD (2007)
    Cisplatin-induced long-term hearing impairment is associated with specific glutathione s-transferase genotypes in testicular cancer survivors
    J Clin Oncol, 25 (6), 708-14
    PubMed 17228018
13. Røyrvik EC, Ahlquist T, Rognes T, Lothe RA (2007)
    Slip slidin' away: a duodecennial review of targeted genes in mismatch repair deficient colorectal cancer
    Crit Rev Oncog, 13 (3), 229-57
    PubMed 18298386
14. Sioud M, Furset G, Cekaite L (2007)
    Suppression of immunostimulatory siRNA-driven innate immune activation by 2'-modified RNAs
    Biochem Biophys Res Commun, 361 (1), 122-6
    PubMed 17658482
15. Skotheim RI, Nees M (2007)
    Alternative splicing in cancer: noise, functional, or systematic?
    Int J Biochem Cell Biol, 39 (7-8), 1432-49
    PubMed 17416541
16. Wu Q, Lind GE, Aasheim HC, Micci F, Silins I, Tropé CG, Nesland JM, Lothe RA, Suo Z (2007)
    The EPH receptor Bs (EPHBs) promoters are unmethylated in colon and ovarian cancers
    Epigenetics, 2 (4), 237-43
    PubMed 18281782
17. Wu Q, Lothe RA, Ahlquist T, Silins I, Tropé CG, Micci F, Nesland JM, Suo Z, Lind GE (2007)
    DNA methylation profiling of ovarian carcinomas and their in vitro models identifies HOXA9, HOXB5, SCGB3A1, and CRABP1 as novel targets
    Mol Cancer, 6, 45
    PubMed 17623056

Publications 2006

1. Barsnes H, Mikalsen SO, Eidhammer I (2006)
   MassSorter: a tool for administrating and analyzing data from mass spectrometry experiments on proteins with known amino acid sequences
   BMC Bioinformatics, 7, 42
   PubMed 16438723
2. Cruciani V, Mikalsen SO (2006)
   The vertebrate connexin family
   Cell Mol Life Sci, 63 (10), 1125-40
   PubMed 16568237
3. Diep CB, Kleivi K, Ribeiro FR, Teixeira MR, Lindgjaerde OC, Lothe RA (2006)
   The order of genetic events associated with colorectal cancer progression inferred from meta-analysis of copy number changes
   Genes Chromosomes Cancer, 45 (1), 31-41
   PubMed 16145679
4. Iacopetta B, Russo A, Bazan V, Dardanoni G, Gebbia N, Soussi T, Kerr D, Elsaleh H, Soong R, Kandioler D, Janschek E, Kappel S, Lung M, Leung CS, Ko JM, Yuen S, Ho J, Leung SY, Crapez E, Duffour J, Ychou M, Leahy DT, O'Donoghue DP, Agnese V, Cascio S et al. (2006)
   Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study
   Ann Oncol, 17 (5), 842-7
   PubMed 16524972
5. Iljin K, Wolf M, Edgren H, Gupta S, Kilpinen S, Skotheim RI, Peltola M, Smit F, Verhaegh G, Schalken J, Nees M, Kallioniemi O (2006)
   TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming
   Cancer Res, 66 (21), 10242-6
   PubMed 17079440
6. Leithe E, Brech A, Rivedal E (2006)
   Endocytic processing of connexin43 gap junctions: a morphological study
   Biochem J, 393 (Pt 1), 59-67
   PubMed 16162097
7. Leithe E, Sirnes S, Omori Y, Rivedal E (2006)
   Downregulation of gap junctions in cancer cells
   Crit Rev Oncog, 12 (3-4), 225-56
   PubMed 17425504
8. Lind GE, Kleivi K, Meling GI, Teixeira MR, Thiis-Evensen E, Rognum TO, Lothe RA (2006)
   ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis
   Cell Oncol, 28 (5-6), 259-72
   PubMed 17167179
9. Lind GE, Skotheim RI, Fraga MF, Abeler VM, Esteller M, Lothe RA (2006)
   Novel epigenetically deregulated genes in testicular cancer include homeobox genes and SCGB3A1 (HIN-1)
   J Pathol, 210 (4), 441-9
   PubMed 17029216
10. Lothe RA, Skotheim RI, Kallioniemi O, Esteller M (2006)
    To the Readers and Future Authors of Critical Reviews in Oncogenesis
    Critical Reviews in Oncogenesis, 12 (1-2), 1-2
    PublikaID 27
11. Prasmickaite L, Cekaite L, Hellum M, Hovig E, Høgset A, Berg K (2006)
    Transcriptome changes in a colon adenocarcinoma cell line in response to photochemical treatment as used in photochemical internalisation (PCI)
    FEBS Lett, 580 (24), 5739-46
    PubMed 17007842
12. Ribeiro FR, Diep CB, Jerónimo C, Henrique R, Lopes C, Eknaes M, Lingjaerde OC, Lothe RA, Teixeira MR (2006)
    Statistical dissection of genetic pathways involved in prostate carcinogenesis
    Genes Chromosomes Cancer, 45 (2), 154-63
    PubMed 16235241
13. Ribeiro FR, Henrique R, Hektoen M, Berg M, Jerónimo C, Teixeira MR, Lothe RA (2006)
    Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas
    Mol Cancer, 5, 33
    PubMed 16952311
14. Ribeiro FR, Jerónimo C, Henrique R, Fonseca D, Oliveira J, Lothe RA, Teixeira MR (2006)
    8q gain is an independent predictor of poor survival in diagnostic needle biopsies from prostate cancer suspects
    Clin Cancer Res, 12 (13), 3961-70
    PubMed 16818693
15. Skotheim RI, Autio R, Lind GE, Kraggerud SM, Andrews PW, Monni O, Kallioniemi O, Lothe RA (2006)
    Novel genomic aberrations in testicular germ cell tumors by array-CGH, and associated gene expression changes
    Cell Oncol, 28 (5-6), 315-26
    PubMed 17167184
16. Storlazzi CT, Brekke HR, Mandahl N, Brosjö O, Smeland S, Lothe RA, Mertens F (2006)
    Identification of a novel amplicon at distal 17q containing the BIRC5/SURVIVIN gene in malignant peripheral nerve sheath tumours
    J Pathol, 209 (4), 492-500
    PubMed 16721726
17. von Eyben FE, Jacobsen GK, Skotheim RI, von der Maase H, Rorth M (2006)
    Precursor lesions in testis and dysgenetic gonads
    Hum Pathol, 37 (6), 773; author reply 774
    PubMed 16733221