Sverre Heim
Position: Professor, MD, PhD
Phone: +47 22 93 44 68
Email:
 

Publications 2017

Agostini A, Brunetti M, Davidson B, Tropé CG, Heim S, Panagopoulos I, Micci F (2017)
Genomic imbalances are involved in miR-30c and let-7a deregulation in ovarian tumors: implications for HMGA2 expression
Oncotarget, 8 (13), 21554-21560
PubMed 28423547

Brunetti M, Agostini A, Davidson B, Tropé CG, Heim S, Panagopoulos I, Micci F (2017)
Recurrent fusion transcripts in squamous cell carcinomas of the vulva
Oncotarget, 8 (10), 16843-16850
PubMed 28186972

Panagopoulos I, Gorunova L, Bjerkehagen B, Andersen K, Lund-Iversen M, Heim S (2017)
Loss of chromosome 13 material in cellular angiofibromas indicates pathogenetic similarity with spindle cell lipomas
Diagn Pathol, 12 (1), 17
PubMed 28193293

Panagopoulos I, Gorunova L, Brunetti M, Agostini A, Andersen HK, Lobmaier I, Bjerkehagen B, Heim S (2017)
Genetic heterogeneity in leiomyomas of deep soft tissue
Oncotarget (in press)
PubMed 28591699

Panagopoulos I, Gorunova L, Lobmaier I, Andersen HK, Bjerkehagen B, Heim S (2017)
Cytogenetic Analysis of a Pseudoangiomatous Pleomorphic/Spindle Cell Lipoma
Anticancer Res, 37 (5), 2219-2223
PubMed 28476785

Panagopoulos I, Gorunova L, Lobmaier I, Bjerkehagen B, Heim S (2017)
Identification of SETD2-NF1 fusion gene in a pediatric spindle cell tumor with the chromosomal translocation t(3;17)(p21;q12)
Oncol Rep, 37 (6), 3181-3188
PubMed 28498454

Panagopoulos I, Gorunova L, Lobmaier I, Bjerkehagen B, Heim S (2017)
Karyotyping and analysis of GNAS locus in intramuscular myxomas
Oncotarget, 8 (13), 22086-22094
PubMed 28160572

Panagopoulos I, Gorunova L, Torkildsen S, Tierens A, Heim S, Micci F (2017)
FAM53B truncation caused by t(10;19)(q26;q13) chromosome translocation in acute lymphoblastic leukemia
Oncol Lett, 13 (4), 2216-2220
PubMed 28454383

Torkildsen S, Brunetti M, Gorunova L, Spetalen S, Beiske K, Heim S, Panagopoulos I (2017)
Rearrangement of the Chromatin Organizer Special AT-rich Binding Protein 1 Gene, SATB1, Resulting from a t(3;5)(p24;q14) Chromosomal Translocation in Acute Myeloid Leukemia
Anticancer Res, 37 (2), 693-698
PubMed 28179318

Publications 2016

Agostini A, Brunetti M, Davidson B, Trope CG, Heim S, Panagopoulos I, Micci F (2016)
Expressions of miR-30c and let-7a are inversely correlated with HMGA2 expression in squamous cell carcinoma of the vulva
Oncotarget, 7 (51), 85058-85062
PubMed 27835588

Agostini A, Gorunova L, Bjerkehagen B, Lobmaier I, Heim S, Panagopoulos I (2016)
Molecular characterization of the t(4;12)(q27~28;q14~15) chromosomal rearrangement in lipoma
Oncol Lett, 12 (3), 1701-1704
PubMed 27588119

Agostini A, Panagopoulos I, Davidson B, Trope CG, Heim S, Micci F (2016)
A novel truncated form of HMGA2 in tumors of the ovaries
Oncol Lett, 12 (2), 1559-1563
PubMed 27446471

Haugvik SP, Vodák D, Haugom L, Hovig E, Gladhaug IP, Heim S, Micci F (2016)
Transcriptomic Profiling of Tumor Aggressiveness in Sporadic Nonfunctioning Pancreatic Neuroendocrine Neoplasms
Pancreas, 45 (8), 1196-203
PubMed 26918873

Johannessen LE, Panagopoulos I, Haugvik SP, Gladhaug IP, Heim S, Micci F (2016)
Upregulation of INS-IGF2 read-through expression and identification of a novel INS-IGF2 splice variant in insulinomas
Oncol Rep, 36 (5), 2653-2662
PubMed 27667266

Micci F, Gorunova L, Agostini A, Johannessen LE, Brunetti M, Davidson B, Heim S, Panagopoulos I (2016)
Cytogenetic and molecular profile of endometrial stromal sarcoma
Genes Chromosomes Cancer, 55 (11), 834-46
PubMed 27219024

Olsen TK, Panagopoulos I, Gorunova L, Micci F, Andersen K, Kilen Andersen H, Meling TR, Due-Tønnessen B, Scheie D, Heim S, Brandal P (2016)
Novel fusion genes and chimeric transcripts in ependymal tumors
Genes Chromosomes Cancer, 55 (12), 944-953
PubMed 27401149

Panagopoulos I, Gorunova L, Agostini A, Lobmaier I, Bjerkehagen B, Heim S (2016)
Fusion of the HMGA2 and C9orf92 genes in myolipoma with t(9;12)(p22;q14)
Diagn Pathol, 11, 22
PubMed 26857357

Panagopoulos I, Gorunova L, Lund-Iversen M, Lobmaier I, Bjerkehagen B, Heim S (2016)
Recurrent fusion of the genes FN1 and ALK in gastrointestinal leiomyomas
Mod Pathol, 29 (11), 1415-1423
PubMed 27469327

Panagopoulos I, Gorunova L, Viset T, Heim S (2016)
Gene fusions AHRR-NCOA2, NCOA2-ETV4, ETV4-AHRR, P4HA2-TBCK, and TBCK-P4HA2 resulting from the translocations t(5;8;17)(p15;q13;q21) and t(4;5)(q24;q31) in a soft tissue angiofibroma
Oncol Rep, 36 (5), 2455-2462
PubMed 27633981

Panagopoulos I, Torkildsen S, Gorunova L, Ulvmoen A, Tierens A, Zeller B, Heim S (2016)
RUNX1 truncation resulting from a cryptic and novel t(6;21)(q25;q22) chromosome translocation in acute myeloid leukemia: A case report
Oncol Rep, 36 (5), 2481-2488
PubMed 27667292

Smebye ML, Haugom L, Davidson B, Trope CG, Heim S, Skotheim RI, Micci F (2016)
Bilateral ovarian carcinomas differ in the expression of metastasis-related genes
Oncol Lett, 13 (1), 184-190
PubMed 28123539

Publications 2015

Agostini A, Panagopoulos I, Andersen HK, Johannesen LE, Davidson B, Tropé CG, Heim S, Micci F (2015)
HMGA2 expression pattern and TERT mutations in tumors of the vulva
Oncol Rep, 33 (6), 2675-80
PubMed 25823555

Hastings RJ, Bown N, Tibiletti MG, Debiec-Rychter M, Vanni R, Espinet B, van Roy N, Roberts P, van den Berg-de-Ruiter E, Bernheim A, Schoumans J, Chatters S, Zemanova Z, Stevens-Kroef M, Simons A, Heim S, Salido M, Ylstra B, Betts DR, Tumour Best Practice meeting, Eurogentest (2015)
Guidelines for cytogenetic investigations in tumours
Eur J Hum Genet, 24 (1), 6-13
PubMed 25804401

Olsen TK, Panagopoulos I, Meling TR, Micci F, Gorunova L, Thorsen J, Due-Tønnessen B, Scheie D, Lund-Iversen M, Krossnes B, Saxhaug C, Heim S, Brandal P (2015)
Fusion genes with ALK as recurrent partner in ependymoma-like gliomas: a new brain tumor entity?
Neuro Oncol, 17 (10), 1365-73
PubMed 25795305

Panagopoulos I, Bjerkehagen B, Gorunova L, Taksdal I, Heim S (2015)
Rearrangement of chromosome bands 12q14~15 causing HMGA2-SOX5 gene fusion and HMGA2 expression in extraskeletal osteochondroma
Oncol Rep, 34 (2), 577-84
PubMed 26043835

Panagopoulos I, Gorunova L, Bjerkehagen B, Heim S (2015)
Novel KAT6B-KANSL1 fusion gene identified by RNA sequencing in retroperitoneal leiomyoma with t(10;17)(q22;q21)
PLoS One, 10 (1), e0117010
PubMed 25621995

Panagopoulos I, Gorunova L, Bjerkehagen B, Heim S (2015)
Fusion of the genes EWSR1 and PBX3 in retroperitoneal leiomyoma with t(9;22)(q33;q12)
PLoS One, 10 (4), e0124288
PubMed 25875009

Panagopoulos I, Gorunova L, Bjerkehagen B, Lobmaier I, Heim S (2015)
The recurrent chromosomal translocation t(12;18)(q14~15;q12~21) causes the fusion gene HMGA2-SETBP1 and HMGA2 expression in lipoma and osteochondrolipoma
Int J Oncol, 47 (3), 884-90
PubMed 26202160

Panagopoulos I, Gorunova L, Bjerkehagen B, Lobmaier I, Heim S (2015)
LAMTOR1-PRKCD and NUMA1-SFMBT1 fusion genes identified by RNA sequencing in aneurysmal benign fibrous histiocytoma with t(3;11)(p21;q13)
Cancer Genet, 208 (11), 545-51
PubMed 26432191

Panagopoulos I, Gorunova L, Bjerkehagen B, Lobmaier I, Heim S (2015)
Fusion of the TBL1XR1 and HMGA1 genes in splenic hemangioma with t(3;6)(q26;p21)
Int J Oncol, 48 (3), 1242-50
PubMed 26708416

Panagopoulos I, Gorunova L, Kerndrup G, Spetalen S, Tierens A, Osnes LT, Andersen K, Müller LS, Hellebostad M, Zeller B, Heim S (2015)
Rare MLL-ELL fusion transcripts in childhood acute myeloid leukemia-association with young age and myeloid sarcomas?
Exp Hematol Oncol, 5, 8
PubMed 26949571

Panagopoulos I, Gorunova L, Taksdal I, Bjerkehagen B, Heim S (2015)
Recurrent 12q13-15 chromosomal aberrations, high frequency of isocitrate dehydrogenase 1 mutations, and absence of high mobility group AT-hook 2 expression in periosteal chondromas
Oncol Lett, 10 (1), 163-167
PubMed 26170993

Tjønnfjord GE, Ly BE, Johannesen TB, Tierens A, Beiske K, Heim S, Jønsson V (2015)
[Chronic lymphatic leukemia in Norway-incidence and prognosis at diagnosis time]
Tidsskr Nor Laegeforen, 135 (18), 1626
PubMed 26442726

Torkildsen S, Gorunova L, Beiske K, Tjønnfjord GE, Heim S, Panagopoulos I (2015)
Novel ZEB2-BCL11B Fusion Gene Identified by RNA-Sequencing in Acute Myeloid Leukemia with t(2;14)(q22;q32)
PLoS One, 10 (7), e0132736
PubMed 26186352

Publications 2014

Haugvik SP, Gorunova L, Haugom L, Eibak AM, Gladhaug IP, Heim S, Micci F (2014)
Loss of 11p11 is a frequent and early event in sporadic nonfunctioning pancreatic neuroendocrine neoplasms
Oncol Rep, 32 (3), 906-12
PubMed 25018013

Heim S (2014)
Boveri at 100: Boveri, chromosomes and cancer
J Pathol, 234 (2), 138-41
PubMed 25043504

Lundin C, Forestier E, Klarskov Andersen M, Autio K, Barbany G, Cavelier L, Golovleva I, Heim S, Heinonen K, Hovland R, Johannsson JH, Kjeldsen E, Nordgren A, Palmqvist L, Johansson B, Nordic Society of Pediatric Hematology Oncology (NOPHO), Swedish Cytogenetic Leukemia Study Group (SCLSG), NOPHO Leukemia Cytogenetic Study Group (NLCSG) (2014)
Clinical and genetic features of pediatric acute lymphoblastic leukemia in Down syndrome in the Nordic countries
J Hematol Oncol, 7, 32
PubMed 24726034

Micci F, Gorunova L, Gatius S, Matias-Guiu X, Davidson B, Heim S, Panagopoulos I (2014)
MEAF6/PHF1 is a recurrent gene fusion in endometrial stromal sarcoma
Cancer Lett, 347 (1), 75-8
PubMed 24530230

Micci F, Haugom L, Abeler VM, Davidson B, Tropé CG, Heim S (2014)
Genomic profile of ovarian carcinomas
BMC Cancer, 14, 315
PubMed 24886194

Micci F, Panagopoulos I, Thorsen J, Davidson B, Tropé CG, Heim S (2014)
Low frequency of ESRRA-C11orf20 fusion gene in ovarian carcinomas
PLoS Biol, 12 (2), e1001784
PubMed 24504521

Olsen TK, Gorunova L, Meling TR, Micci F, Scheie D, Due-Tønnessen B, Heim S, Brandal P (2014)
Genomic characterization of ependymomas reveals 6q loss as the most common aberration
Oncol Rep, 32 (2), 483-90
PubMed 24939246

Panagopoulos I, Bjerkehagen B, Gorunova L, Berner JM, Boye K, Heim S (2014)
Several fusion genes identified by whole transcriptome sequencing in a spindle cell sarcoma with rearrangements of chromosome arm 12q and MDM2 amplification
Int J Oncol, 45 (5), 1829-36
PubMed 25176350

Panagopoulos I, Brandal P, Gorunova L, Bjerkehagen B, Heim S (2014)
Novel CSF1-S100A10 fusion gene and CSF1 transcript identified by RNA sequencing in tenosynovial giant cell tumors
Int J Oncol, 44 (5), 1425-32
PubMed 24604026

Panagopoulos I, Gorunova L, Bjerkehagen B, Boye K, Heim S (2014)
Chromosome aberrations and HEY1-NCOA2 fusion gene in a mesenchymal chondrosarcoma
Oncol Rep, 32 (1), 40-4
PubMed 24839999

Panagopoulos I, Gorunova L, Bjerkehagen B, Heim S (2014)
The "grep" command but not FusionMap, FusionFinder or ChimeraScan captures the CIC-DUX4 fusion gene from whole transcriptome sequencing data on a small round cell tumor with t(4;19)(q35;q13)
PLoS One, 9 (6), e99439
PubMed 24950227

Panagopoulos I, Gorunova L, Davidson B, Heim S (2014)
Novel TNS3-MAP3K3 and ZFPM2-ELF5 fusion genes identified by RNA sequencing in multicystic mesothelioma with t(7;17)(p12;q23) and t(8;11)(q23;p13)
Cancer Lett, 357 (2), 502-9
PubMed 25484136

Panagopoulos I, Thorsen J, Gorunova L, Micci F, Heim S (2014)
Sequential combination of karyotyping and RNA-sequencing in the search for cancer-specific fusion genes
Int J Biochem Cell Biol, 53, 462-5
PubMed 24863361

Panagopoulos I, Torkildsen S, Gorunova L, Tierens A, Tjønnfjord GE, Heim S (2014)
Comparison between karyotyping-FISH-reverse transcription PCR and RNA-sequencing-fusion gene identification programs in the detection of KAT6A-CREBBP in acute myeloid leukemia
PLoS One, 9 (5), e96570
PubMed 24798186

Smebye ML, Sveen A, Haugom L, Davidson B, Tropé CG, Lothe RA, Heim S, Skotheim RI, Micci F (2014)
Chromosome 19 rearrangements in ovarian carcinomas: zinc finger genes are particularly targeted
Genes Chromosomes Cancer, 53 (7), 558-67
PubMed 24634323

Publications 2013

Fiskvik I, Aamot HV, Delabie J, Smeland EB, Stokke T, Heim S, Holte H (2013)
Karyotyping of diffuse large B-cell lymphomas: loss of 17p is associated with poor patient outcome
Eur J Haematol, 91 (4), 332-8
PubMed 23859481

Fløisand Y, Beiske K, Tjønnfjord GE, Heldal D, Bjerkehagen B, Revheim ME, Heim S, Bruland OS, Hall KS, Tierens A, Delabie J (2013)
Malignant phyllodes tumor and acute megakaryoblastic leukemia sharing a common clonal origin
Case Rep Hematol, 2013, 934781
PubMed 24455338

Håvik AB, Lind GE, Honne H, Meling TR, Scheie D, Hall KS, van den Berg E, Mertens F, Picci P, Lothe RA, Heim S, Brandal P (2013)
Sequencing IDH1/2 glioma mutation hotspots in gliomas and malignant peripheral nerve sheath tumors
Neuro Oncol, 16 (2), 320-2
PubMed 24311631

Micci F, Panagopoulos I, Haugom L, Dahlback HS, Pretorius ME, Davidson B, Abeler VM, Tropé CG, Danielsen HE, Heim S (2013)
Genomic aberration patterns and expression profiles of squamous cell carcinomas of the vulva
Genes Chromosomes Cancer, 52 (6), 551-63
PubMed 23404381

Onkes W, Fredrik R, Micci F, Schönbeck BJ, Martin-Subero JI, Ullmann R, Hilpert F, Bräutigam K, Janssen O, Maass N, Siebert R, Heim S, Arnold N, Weimer J (2013)
Breakpoint characterization of the der(19)t(11;19)(q13;p13) in the ovarian cancer cell line SKOV-3
Genes Chromosomes Cancer, 52 (5), 512-22
PubMed 23362175

Panagopoulos I, Gorunova L, Brandal P, Garnes M, Tierens A, Heim S (2013)
Myeloid leukemia with t(7;21)(p22;q22) and 5q deletion
Oncol Rep, 30 (4), 1549-52
PubMed 23877199

Panagopoulos I, Gorunova L, Zeller B, Tierens A, Heim S (2013)
Cryptic FUS-ERG fusion identified by RNA-sequencing in childhood acute myeloid leukemia
Oncol Rep, 30 (6), 2587-92
PubMed 24068373

Panagopoulos I, Micci F, Thorsen J, Haugom L, Buechner J, Kerndrup G, Tierens A, Zeller B, Heim S (2013)
Fusion of ZMYND8 and RELA genes in acute erythroid leukemia
PLoS One, 8 (5), e63663
PubMed 23667654

Panagopoulos I, Thorsen J, Gorunova L, Haugom L, Bjerkehagen B, Davidson B, Heim S, Micci F (2013)
Fusion of the ZC3H7B and BCOR genes in endometrial stromal sarcomas carrying an X;22-translocation
Genes Chromosomes Cancer, 52 (7), 610-8
PubMed 23580382

Panagopoulos I, Thorsen J, Gorunova L, Micci F, Haugom L, Davidson B, Heim S (2013)
RNA sequencing identifies fusion of the EWSR1 and YY1 genes in mesothelioma with t(14;22)(q32;q12)
Genes Chromosomes Cancer, 52 (8), 733-40
PubMed 23630070

Paulsson K, Forestier E, Andersen MK, Autio K, Barbany G, Borgström G, Cavelier L, Golovleva I, Heim S, Heinonen K, Hovland R, Johannsson JH, Kjeldsen E, Nordgren A, Palmqvist L, Johansson B, Nordic Society of Pediatric Hematology and Oncology (NOPHO), Swedish Cytogenetic Leukemia Study Group (SCLSG), NOPHO Leukemia Cytogenetic Study Group (NLCSG) (2013)
High modal number and triple trisomies are highly correlated favorable factors in childhood B-cell precursor high hyperdiploid acute lymphoblastic leukemia treated according to the NOPHO ALL 1992/2000 protocols
Haematologica, 98 (9), 1424-32
PubMed 23645689

Publications 2012

Barbany G, Andersen MK, Autio K, Borgström G, Franco LC, Golovleva I, Heim S, Heinonen K, Hovland R, Johansson B, Johannsson JH, Kjeldsen E, Nordgren A, Palmqvist L, Forestier E, Nordic Society of Paediatric Haematology and Oncology, Swedish Cytogenetic Leukaemia Study Group, NOPHO Leukaemia Cytogenetic Study Group (2012)
Additional aberrations of the ETV6 and RUNX1 genes have no prognostic impact in 229 t(12;21)(p13;q22)-positive B-cell precursor acute lymphoblastic leukaemias treated according to the NOPHO-ALL-2000 protocol
Leuk Res, 36 (7), 936-8
PubMed 22521551

Håvik AB, Brandal P, Honne H, Dahlback HS, Scheie D, Hektoen M, Meling TR, Helseth E, Heim S, Lothe RA, Lind GE (2012)
MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCR
J Transl Med, 10, 36
PubMed 22390413

Micci F, Thorsen J, Panagopoulos I, Nyquist KB, Zeller B, Tierens A, Heim S (2012)
High-throughput sequencing identifies an NFIA/CBFA2T3 fusion gene in acute erythroid leukemia with t(1;16)(p31;q24)
Leukemia, 27 (4), 980-2
PubMed 23032695

Nyquist KB, Panagopoulos I, Thorsen J, Haugom L, Gorunova L, Bjerkehagen B, Fosså A, Guriby M, Nome T, Lothe RA, Skotheim RI, Heim S, Micci F (2012)
Whole-transcriptome sequencing identifies novel IRF2BP2-CDX1 fusion gene brought about by translocation t(1;5)(q42;q32) in mesenchymal chondrosarcoma
PLoS One, 7 (11), e49705
PubMed 23185413

Nyquist KB, Panagopoulos I, Thorsen J, Roberto R, Wik HS, Tierens A, Heim S, Micci F (2012)
t(12;13)(q14;q31) leading to HMGA2 upregulation in acute myeloid leukaemia
Br J Haematol, 157 (6), 769-71
PubMed 22404713

Panagopoulos I, Micci F, Thorsen J, Gorunova L, Eibak AM, Bjerkehagen B, Davidson B, Heim S (2012)
Novel fusion of MYST/Esa1-associated factor 6 and PHF1 in endometrial stromal sarcoma
PLoS One, 7 (6), e39354
PubMed 22761769

Panagopoulos I, Micci F, Thorsen J, Haugom L, Tierens A, Ulvmoen A, Heim S (2012)
A novel TCF3-HLF fusion transcript in acute lymphoblastic leukemia with a t(17;19)(q22;p13)
Cancer Genet, 205 (12), 669-72
PubMed 23181981

Thorsen J, Aamot HV, Roberto R, Tjønnfjord GE, Micci F, Heim S (2012)
Myelodysplastic syndrome with a t(2;11)(p21;q23-24) and translocation breakpoint close to miR-125b-1
Cancer Genet, 205 (10), 528-32
PubMed 22944560

Tjønnfjord GE, Ly BE, Johannesen TB, Tierens A, Beiske K, Heim S, Jønsson V (2012)
Chronic lymphocytic leukaemia in Norway--incidence and prognostic markers at diagnosis
Tidsskr Nor Laegeforen, 132 (18), 2056-9
PubMed 23038195

Publications 2011

Andersen MK, Autio K, Barbany G, Borgström G, Cavelier L, Golovleva I, Heim S, Heinonen K, Hovland R, Johannsson JH, Johansson B, Kjeldsen E, Nordgren A, Palmqvist L, Forestier E (2011)
Paediatric B-cell precursor acute lymphoblastic leukaemia with t(1;19)(q23;p13): clinical and cytogenetic characteristics of 47 cases from the Nordic countries treated according to NOPHO protocols
Br J Haematol, 155 (2), 235-43
PubMed 21902680

Dahlback HS, Brandal P, Gorunova L, Widing E, Meling TR, Krossnes BK, Heim S (2011)
Genomic aberrations in pediatric gliomas and embryonal tumors
Genes Chromosomes Cancer, 50 (10), 788-99
PubMed 21717527

Dahlback HS, Brandal P, Krossnes BK, Fric R, Meling TR, Meza-Zepeda LA, Danielsen HE, Heim S (2011)
Multiple chromosomal monosomies are characteristic of giant cell ependymoma
Hum Pathol, 42 (12), 2042-6
PubMed 21683982

Dahlback HS, Gorunova L, Brandal P, Scheie D, Helseth E, Meling TR, Heim S (2011)
Genomic aberrations in diffuse low-grade gliomas
Genes Chromosomes Cancer, 50 (6), 409-20
PubMed 21412929

Dahlback HS, Gorunova L, Micci F, Scheie D, Brandal P, Meling TR, Heim S (2011)
Molecular cytogenetic analysis of a gliosarcoma with osseous metaplasia
Cytogenet Genome Res, 134 (2), 88-95
PubMed 21555877

Gorunova L, Bjerkehagen B, Heim S (2011)
Paratesticular leiomyoma with a der(14)t(12;14)(q15;q24)
Cancer Genet, 204 (8), 465-8
PubMed 21962898

Kildal W, Micci F, Risberg B, Abeler VM, Kristensen GB, Heim S, Danielsen HE (2011)
Genomic imbalances in endometrial adenocarcinomas - comparison of DNA ploidy, karyotyping and comparative genomic hybridization
Mol Oncol, 6 (1), 98-107
PubMed 22062770

Kyriazoglou AI, Dimitriadis E, Arnogiannaki N, Brandal P, Heim S, Pandis N (2011)
Similar cytogenetic findings in two synchronous secondary peripheral chondrosarcomas in a patient with multiple osteochondromas
Cancer Genet, 204 (12), 677-81
PubMed 22285020

Micci F, Thorsen J, Haugom L, Zeller B, Tierens A, Heim S (2011)
Translocation t(1;16)(p31;q24) rearranging CBFA2T3 is specific for acute erythroid leukemia
Leukemia, 25 (9), 1510-2
PubMed 21606959

Nyquist KB, Thorsen J, Zeller B, Haaland A, Trøen G, Heim S, Micci F (2011)
Identification of the TAF15-ZNF384 fusion gene in two new cases of acute lymphoblastic leukemia with a t(12;17)(p13;q12)
Cancer Genet, 204 (3), 147-52
PubMed 21504714

Randen U, Yri OE, Tierens A, Heim S, Beiske K, Delabie J (2011)
Mantle cell lymphoma with features of marginal-zone lymphoma
J Hematop, 4 (1), 7-11
PubMed 25089161

Teixeira MR, Heim S (2011)
Cytogenetic analysis of tumor clonality
Adv Cancer Res, 112, 127-49
PubMed 21925303

Thorsen J, Micci F, Heim S (2011)
Identification of chromosomal breakpoints of cancer-specific translocations by rolling circle amplification and long-distance inverse PCR
Cancer Genet, 204 (8), 458-61
PubMed 21962896

Warsame AA, Aasheim HC, Nustad K, Trøen G, Tierens A, Wang V, Randen U, Dong HP, Heim S, Brech A, Delabie J (2011)
Splenic marginal zone lymphoma with VH1-02 gene rearrangement expresses poly- and self-reactive antibodies with similar reactivity
Blood, 118 (12), 3331-9
PubMed 21725051

Publications 2010

Brandal P, Teixeira MR, Heim S (2010)
Genotypic and phenotypic classification of cancer: How should the impact of the two diagnostic approaches best be balanced?
Genes Chromosomes Cancer, 49 (9), 763-74
PubMed 20607708

Micci F, Haugom L, Ahlquist T, Andersen HK, Abeler VM, Davidson B, Trope CG, Lothe RA, Heim S (2010)
Genomic aberrations in borderline ovarian tumors
J Transl Med, 8, 21
PubMed 20184781

Micci F, Skotheim RI, Haugom L, Weimer J, Eibak AM, Abeler VM, Trope CG, Arnold N, Lothe RA, Heim S (2010)
Array-CGH analysis of microdissected chromosome 19 markers in ovarian carcinoma identifies candidate target genes
Genes Chromosomes Cancer, 49 (11), 1046-53
PubMed 20725991

Publications 2009

Brandal P, Panagopoulos I, Bjerkehagen B, Heim S (2009)
t(19;22)(q13;q12) Translocation leading to the novel fusion gene EWSR1-ZNF444 in soft tissue myoepithelial carcinoma
Genes Chromosomes Cancer, 48 (12), 1051-6
PubMed 19760602

Dahlback HS, Brandal P, Meling TR, Gorunova L, Scheie D, Heim S (2009)
Genomic aberrations in 80 cases of primary glioblastoma multiforme: Pathogenetic heterogeneity and putative cytogenetic pathways
Genes Chromosomes Cancer, 48 (10), 908-24
PubMed 19603525

Danielsen SA, Lind GE, Biornslett M, Meling GI, Rognum TO, Heim S, Lothe RA (2009)
Novel Mutations of the Suppressor Gene PTEN in Colorectal Carcinomas Stratified by Microsatellite Instability- and TP53 Mutation- Status (vol 29, pg E252, 2008)
Hum. Mutat., 30 (6), 1023

Gorunova L, Vult von Steyern F, Storlazzi CT, Bjerkehagen B, Follerås G, Heim S, Mandahl N, Mertens F (2009)
Cytogenetic analysis of 101 giant cell tumors of bone: nonrandom patterns of telomeric associations and other structural aberrations
Genes Chromosomes Cancer, 48 (7), 583-602
PubMed 19396867

Karrman K, Forestier E, Heyman M, Andersen MK, Autio K, Blennow E, Borgström G, Ehrencrona H, Golovleva I, Heim S, Heinonen K, Hovland R, Johannsson JH, Kerndrup G, Nordgren A, Palmqvist L, Johansson B, Nordic Society of Pediatric Hematology, Oncology (NOPHO), Swedish Cytogenetic Leukemia Study Group (SCLSG), NOPHO Leukemia Cytogenetic Study Group (NLCSG) (2009)
Clinical and cytogenetic features of a population-based consecutive series of 285 pediatric T-cell acute lymphoblastic leukemias: rare T-cell receptor gene rearrangements are associated with poor outcome
Genes Chromosomes Cancer, 48 (9), 795-805
PubMed 19530250

Micci F, Haugom L, Ahlquist T, Abeler VM, Trope CG, Lothe RA, Heim S (2009)
Tumor spreading to the contralateral ovary in bilateral ovarian carcinoma is a late event in clonal evolution
J Oncol, 2010, 646340
PubMed 19759843

Micci F, Panagopoulos I, Haugom L, Andersen HK, Tjønnfjord GE, Beiske K, Heim S (2009)
t(3;21)(q22;q22) leading to truncation of the RYK gene in atypical chronic myeloid leukemia
Cancer Lett, 277 (2), 205-11
PubMed 19168282

Micci F, Weimer J, Haugom L, Skotheim RI, Grunewald R, Abeler VM, Silins I, Lothe RA, Trope CG, Arnold N, Heim S (2009)
Reverse painting of microdissected chromosome 19 markers in ovarian carcinoma identifies a complex rearrangement map
Genes Chromosomes Cancer, 48 (2), 184-93
PubMed 18973136

Santos J, Cerveira N, Bizarro S, Ribeiro FR, Correia C, Torres L, Lisboa S, Vieira J, Mariz JM, Norton L, Snijder S, Mellink CH, Buijs A, Shih LY, Strehl S, Micci F, Heim S, Teixeira MR (2009)
Expression pattern of the septin gene family in acute myeloid leukemias with and without MLL-SEPT fusion genes
Leuk Res, 34 (5), 615-21
PubMed 19748670

Skotheim RI, Thomassen GO, Eken M, Lind GE, Micci F, Ribeiro FR, Cerveira N, Teixeira MR, Heim S, Rognes T, Lothe RA (2009)
A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis
Mol Cancer, 8, 5
PubMed 19152679

Publications 2008

Brandal P, Panagopoulos I, Bjerkehagen B, Gorunova L, Skjeldal S, Micci F, Heim S (2008)
Detection of a t(1;22)(q23;q12) translocation leading to an EWSR1-PBX1 fusion gene in a myoepithelioma
Genes Chromosomes Cancer, 47 (7), 558-64
PubMed 18383210

Cerveira N, Micci F, Santos J, Pinheiro M, Correia C, Lisboa S, Bizarro S, Norton L, Glomstein A, Asberg AE, Heim S, Teixeira MR (2008)
Molecular characterization of the MLL-SEPT6 fusion gene in acute myeloid leukemia: identification of novel fusion transcripts and cloning of genomic breakpoint junctions
Haematologica, 93 (7), 1076-80
PubMed 18492691

Danielsen SA, Lind GE, Bjørnslett M, Meling GI, Rognum TO, Heim S, Lothe RA (2008)
Novel mutations of the suppressor gene PTEN in colorectal carcinomas stratified by microsatellite instability- and TP53 mutation- status
Hum Mutat, 29 (11), E252-62
PubMed 18781614

Forestier E, Gauffin F, Andersen MK, Autio K, Borgström G, Golovleva I, Gustafsson B, Heim S, Heinonen K, Heyman M, Hovland R, Johannsson JH, Kerndrup G, Rosenquist R, Schoumans J, Swolin B, Johansson B, Nordgren A, Nordic Society of Pediatric Hematology and Oncology, Swedish Cytogenetic Leukemia Study Group, NOPHO Leukemia Cytogenetic Study Group (2008)
Clinical and cytogenetic features of pediatric dic(9;20)(p13.2;q11.2)-positive B-cell precursor acute lymphoblastic leukemias: a Nordic series of 24 cases and review of the literature
Genes Chromosomes Cancer, 47 (2), 149-58
PubMed 17990329

Forestier E, Heyman M, Andersen MK, Autio K, Blennow E, Borgström G, Golovleva I, Heim S, Heinonen K, Hovland R, Johannsson JH, Kerndrup G, Nordgren A, Rosenquist R, Swolin B, Johansson B, Nordic Society of Paediatric Haematology, Oncology (NOPHO), Swedish Cytogenetic Leukaemia Study Group (SCLSG), NOPHO Leukaemia Cytogenetic Study Group (NLCSG) (2008)
Outcome of ETV6/RUNX1-positive childhood acute lymphoblastic leukaemia in the NOPHO-ALL-1992 protocol: frequent late relapses but good overall survival
Br J Haematol, 140 (6), 665-72
PubMed 18241254

Heim S, Mitelman F (2008)
Molecular screening for new fusion genes in cancer
Nat Genet, 40 (6), 685-6
PubMed 18509307

Micci F, Haugom L, Abeler VM, Tropé CG, Danielsen HE, Heim S (2008)
Consistent numerical chromosome aberrations in thecofibromas of the ovary
Virchows Arch, 452 (3), 269-76
PubMed 18188592

Publications 2007

Forestier E, Andersen MK, Autio K, Blennow E, Borgström G, Golovleva I, Heim S, Heinonen K, Hovland R, Johannsson JH, Kerndrup G, Nordgren A, Rosenquist R, Swolin B, Johansson B, Nordic Society of Pediatric Hematology and Oncology (NOPHO), Swedish Cytogenetic Leukemia Study Group (SCLSG), NOPHO Leukemia Cytogenetic Study Group (NLCSG) (2007)
Cytogenetic patterns in ETV6/RUNX1-positive pediatric B-cell precursor acute lymphoblastic leukemia: A Nordic series of 245 cases and review of the literature
Genes Chromosomes Cancer, 46 (5), 440-50
PubMed 17285576

Ikonomou IM, Aamot HV, Heim S, Fosså A, Delabie J (2007)
Granulomatous slack skin with a translocation t(3;9)(q12;p24)
Am J Surg Pathol, 31 (5), 803-6
PubMed 17460466

Micci F, Bjerkehagen B, Heim S (2007)
Pairwise comparison of genomic imbalances between primary and recurrent well differentiated liposarcomas
Cancer Genet Cytogenet, 178 (2), 163-7
PubMed 17954275

Micci F, Haugom L, Abeler VM, Bjerkehagen B, Heim S (2007)
Trisomy 7 in postoperative spindle cell nodules
Cancer Genet Cytogenet, 174 (2), 147-50
PubMed 17452257

Micci F, Panagopoulos I, Tjønnfjord GE, Kolstad A, Delabie J, Beiske K, Heim S (2007)
Molecular cytogenetic characterization of t(14;19)(q32;p13), a new recurrent translocation in B cell malignancies
Virchows Arch, 450 (5), 559-65
PubMed 17406891

Aamot HV, Torlakovic EE, Eide MB, Holte H, Heim S (2007)
Non-Hodgkin lymphoma with t(14;18): clonal evolution patterns and cytogenetic-pathologic-clinical correlations
J Cancer Res Clin Oncol, 133 (7), 455-70
PubMed 17235551

Publications 2006

Brandal P, Bjerkehagen B, Heim S (2006)
Rearrangement of chromosomal region 8q11-13 in lipomatous tumours: correlation with lipoblastoma morphology
J Pathol, 208 (3), 388-94
PubMed 16308870

Brandal P, Lie AK, Bassarova A, Svindland A, Risberg B, Danielsen H, Heim S (2006)
Genomic aberrations in mucinous tubular and spindle cell renal cell carcinomas
Mod Pathol, 19 (2), 186-94
PubMed 16258504

Ikonomou IM, Tierens A, Troen G, Aamot HV, Heim S, Lauritzsen GF, Vålerhaugen H, Delabie J (2006)
Peripheral T-cell lymphoma with involvement of the expanded mantle zone
Virchows Arch, 449 (1), 78-87
PubMed 16633785

Karrman K, Forestier E, Andersen MK, Autio K, Borgström G, Heim S, Heinonen K, Hovland R, Kerndrup G, Johansson B, Nordic Society of Paediatric Haematology and Oncology (NOPHO) and the NOPHO Leukaemia Cytogenetic Study Group (NLCSG) (2006)
High incidence of the ETV6/RUNX1 fusion gene in paediatric precursor B-cell acute lymphoblastic leukaemias with trisomy 21 as the sole cytogenetic change: a Nordic series of cases diagnosed 1989-2005
Br J Haematol, 135 (3), 352-4
PubMed 16965388

Micci F, Panagopoulos I, Bjerkehagen B, Heim S (2006)
Consistent rearrangement of chromosomal band 6p21 with generation of fusion genes JAZF1/PHF1 and EPC1/PHF1 in endometrial stromal sarcoma
Cancer Res, 66 (1), 107-12
PubMed 16397222

Micci F, Panagopoulos I, Bjerkehagen B, Heim S (2006)
Deregulation of HMGA2 in an aggressive angiomyxoma with t(11;12)(q23;q15)
Virchows Arch, 448 (6), 838-42
PubMed 16568309

Torres L, Ribeiro FR, Pandis N, Andersen JA, Heim S, Teixeira MR (2006)
Intratumor genomic heterogeneity in breast cancer with clonal divergence between primary carcinomas and lymph node metastases
Breast Cancer Res Treat, 102 (2), 143-55
PubMed 16906480

Aamot HV, Tjønnfjord GE, Delabie J, Heim S (2006)
Molecular cytogenetic analysis of leukemic mantle cell lymphoma with a cryptic t(11;14)
Cancer Genet Cytogenet, 165 (2), 172-5
PubMed 16527613

Publications 2005

Brandal P, Bjerkehagen B, Danielsen H, Heim S (2005)
Chromosome 7 abnormalities are common in chordomas
Cancer Genet Cytogenet, 160 (1), 15-21
PubMed 15949565

Brandal P, Busund LT, Heim S (2005)
Chromosome abnormalities in juxtaglomerular cell tumors
Cancer, 104 (3), 504-10
PubMed 15968688

Kleivi K, Diep CB, Pandis N, Heim S, Teixeira MR, Lothe RA (2005)
TP53 mutations are associated with a particular pattern of genomic imbalances in breast carcinomas
J Pathol, 207 (1), 14-9
PubMed 16007576

Teixeira MR, Heim S (2005)
Multiple numerical chromosome aberrations in cancer: what are their causes and what are their consequences?
Semin Cancer Biol, 15 (1), 3-12
PubMed 15613283

Aamot HV, Bjørnslett M, Delabie J, Heim S (2005)
t(14;22)(q32;q11) in non-Hodgkin lymphoma and myeloid leukaemia: molecular cytogenetic investigations
Br J Haematol, 130 (6), 845-51
PubMed 16156854

Aamot HV, Micci F, Holte H, Delabie J, Heim S (2005)
G-banding and molecular cytogenetic analyses of marginal zone lymphoma
Br J Haematol, 130 (6), 890-901
PubMed 16156859

Publications 2004

Bardi G, Fenger C, Johansson B, Mitelman F, Heim S (2004)
Tumor karyotype predicts clinical outcome in colorectal cancer patients
J Clin Oncol, 22 (13), 2623-34
PubMed 15226330

Brandal P, Bjerkehagen B, Heim S (2004)
Molecular cytogenetic characterization of tenosynovial giant cell tumors
Neoplasia, 6 (5), 578-83
PubMed 15548367

Micci F, Teixeira MR, Haugom L, Kristensen G, Abeler VM, Heim S (2004)
Genomic aberrations in carcinomas of the uterine corpus
Genes Chromosomes Cancer, 40 (3), 229-46
PubMed 15139002

Teixeira MR, Ribeiro FR, Eknaes M, Waehre H, Stenwig AE, Giercksky KE, Heim S, Lothe RA (2004)
Genomic analysis of prostate carcinoma specimens obtained via ultrasound-guided needle biopsy may be of use in preoperative decision-making
Cancer, 101 (8), 1786-93
PubMed 15386312

Publications 2003

Adeyinka A, Baldetorp B, Mertens F, Olsson H, Johannsson O, Heim S, Pandis N (2003)
Comparative cytogenetic and DNA flow cytometric analysis of 242 primary breast carcinomas
Cancer Genet Cytogenet, 147 (1), 62-7
PubMed 14580772

Brandal P, Micci F, Bjerkehagen B, Eknaes M, Larramendy M, Lothe RA, Knuutila S, Heim S (2003)
Molecular cytogenetic characterization of desmoid tumors
Cancer Genet Cytogenet, 146 (1), 1-7
PubMed 14499689

Fadl-Elmula I, Gorunova L, Mandahl N, Heim S (2003)
Chromosomal abnormalities in inflammatory pseudotumor of the urinary bladder
Cancer Genet Cytogenet, 143 (2), 169-71
PubMed 12781452

Forestier E, Heim S, Blennow E, Borgström G, Holmgren G, Heinonen K, Johannsson J, Kerndrup G, Andersen MK, Lundin C, Nordgren A, Rosenquist R, Swolin B, Johansson B, Nordic Society of Paediatric Haematology and Oncology (NOPHO), Swedish Cytogenetic Leukaemia Study Group (SCLSG), NOPHO Leukaemia Cytogenetic Study Group (NLCSG) (2003)
Cytogenetic abnormalities in childhood acute myeloid leukaemia: a Nordic series comprising all children enrolled in the NOPHO-93-AML trial between 1993 and 2001
Br J Haematol, 121 (4), 566-77
PubMed 12752097

Ioannidis P, Mahaira L, Papadopoulou A, Teixeira MR, Heim S, Andersen JA, Evangelou E, Dafni U, Pandis N, Trangas T (2003)
8q24 Copy number gains and expression of the c-myc mRNA stabilizing protein CRD-BP in primary breast carcinomas
Int J Cancer, 104 (1), 54-9
PubMed 12532419

Kildal W, Kraggerud SM, Abeler VM, Heim S, Tropé CG, Kristensen GB, Risberg B, Lothe RA, Danielsen HE (2003)
Genome profiles of bilateral dysgerminomas, a unilateral gonadoblastoma, and a metastasis from a 46, XY phenotypic female
Hum Pathol, 34 (9), 946-9
PubMed 14562293

Micci F, Teixeira MR, Scheistrøen M, Abeler VM, Heim S (2003)
Cytogenetic characterization of tumors of the vulva and vagina
Genes Chromosomes Cancer, 38 (2), 137-48
PubMed 12939741

Micci F, Walter CU, Teixeira MR, Panagopoulos I, Bjerkehagen B, Saeter G, Heim S (2003)
Cytogenetic and molecular genetic analyses of endometrial stromal sarcoma: nonrandom involvement of chromosome arms 6p and 7p and confirmation of JAZF1/JJAZ1 gene fusion in t(7;17)
Cancer Genet Cytogenet, 144 (2), 119-24
PubMed 12850374

Normann AP, Egeland T, Madshus IH, Heim S, Tjønnfjord GE (2003)
CD7 expression by CD34+ cells in CML patients, of prognostic significance?
Eur J Haematol, 71 (4), 266-75
PubMed 12950236

Papadopoulou A, Trangas T, Teixeira MR, Heim S, Dimitriadis E, Tsarouha H, Andersen JA, Evangelou E, Ioannidis P, Agnantis NJ, Pandis N (2003)
Telomerase activity and genetic alterations in primary breast carcinomas
Neoplasia, 5 (2), 170-8
PubMed 12659690

Teixeira MR, Pandis N, Heim S (2003)
Multicentric mammary carcinoma: evidence of monoclonal proliferation
Cancer, 97 (3), 715-7; author reply 717
PubMed 12548617

Publications 2002

Fadl-Elmula I, Kytola S, Leithy ME, Abdel-Hameed M, Mandahl N, Elagib A, Ibrahim M, Larsson C, Heim S (2002)
Chromosomal aberrations in benign and malignant bilharzia-associated bladder lesions analyzed by comparative genomic hybridization
BMC Cancer, 2, 5
PubMed 11914143

Ikonomou IM, Nesland JM, Schjølseth SA, Heim S, Delabie J (2002)
Mantle cell lymphoma with Homer-Wright rosettes
Virchows Arch, 442 (2), 179-82
PubMed 12596071

Kleivi K, Lothe RA, Heim S, Tsarouha H, Kraggerud SM, Pandis N, Papadopoulou A, Andersen J, Jakobsen KS, Teixeira MR (2002)
Genome profiling of breast cancer cells selected against in vitro shows copy number changes
Genes Chromosomes Cancer, 33 (3), 304-9
PubMed 11807988

Panagopoulos I, Mertens F, Isaksson M, Domanski HA, Brosjö O, Heim S, Bjerkehagen B, Sciot R, Dal Cin P, Fletcher JA, Fletcher CD, Mandahl N (2002)
Molecular genetic characterization of the EWS/CHN and RBP56/CHN fusion genes in extraskeletal myxoid chondrosarcoma
Genes Chromosomes Cancer, 35 (4), 340-52
PubMed 12378528

Teixeira MR, Pandis N, Heim S (2002)
Cytogenetic clues to breast carcinogenesis
Genes Chromosomes Cancer, 33 (1), 1-16
PubMed 11746982