Publications

Publications by Jan E. Brinchmann

61 publications found

Publications in press

1. Beitnes JO, Oie E, Shahdadfar A, Karlsen T, Müller RM, Aakhus S, Reinholt FP, Brinchmann JE
   Intramyocardial injections of human mesenchymal stem cells following acute myocardial infarction modulate scar formation and improve left ventricular function
   Cell Transplant (in press)
   PubMed 22410280

Publications 2012

1. Szöke K, Beckstrøm KJ, Brinchmann JE (2012)
   Human adipose tissue as a source of cells with angiogenic potential
   Cell Transplant, 21 (1), 235-50
   PubMed 21669039

Publications 2011

1. Beitnes JO, Lunde K, Brinchmann JE, Aakhus S (2011)
   Stem cells for cardiac repair in acute myocardial infarction
   Expert Rev Cardiovasc Ther, 9 (8), 1015-25
   PubMed 21878046
2. Duggal S, Brinchmann JE (2011)
   Importance of serum source for the in vitro replicative senescence of human bone marrow derived mesenchymal stem cells
   J Cell Physiol, 226 (11), 2908-15
   PubMed 21302288
3. Herlofsen SR, Küchler AM, Melvik JE, Brinchmann JE (2011)
   Chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells in self-gelling alginate discs reveals novel chondrogenic signature gene clusters
   Tissue Eng Part A, 17 (7-8), 1003-13
   PubMed 21087199
4. Karlsen TA, Mirtaheri P, Shahdadfar A, Fløisand Y, Brinchmann JE (2011)
   Effect of three-dimensional culture and incubator gas concentration on phenotype and differentiation capability of human mesenchymal stem cells
   J Cell Biochem, 112 (2), 684-93
   PubMed 21268090
5. Karlsen TA, Shahdadfar A, Brinchmann JE (2011)
   Human primary articular chondrocytes, chondroblasts-like cells, and dedifferentiated chondrocytes: differences in gene, microRNA, and protein expression and phenotype
   Tissue Eng Part C Methods, 17 (2), 219-27
   PubMed 20799885

Publications 2010

1. Jakobsen RB, Shahdadfar A, Reinholt FP, Brinchmann JE (2010)
   Chondrogenesis in a hyaluronic acid scaffold: comparison between chondrocytes and MSC from bone marrow and adipose tissue
   Knee Surg Sports Traumatol Arthrosc, 18 (10), 1407-16
   PubMed 20020100

Publications 2009

1. Beitnes JO, Hopp E, Lunde K, Solheim S, Arnesen H, Brinchmann JE, Forfang K, Aakhus S (2009)
   Long-term results after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: the ASTAMI randomised, controlled study
   Heart, 95 (24), 1983-9
   PubMed 19833610
2. Duggal S, Frønsdal KB, Szöke K, Shahdadfar A, Melvik JE, Brinchmann JE (2009)
   Phenotype and gene expression of human mesenchymal stem cells in alginate scaffolds
   Tissue Eng Part A, 15 (7), 1763-73
   PubMed 19115828
3. Hildrestrand GA, Duggal S, Bjørås M, Luna L, Brinchmann JE (2009)
   Modulation of DNA glycosylase activities in mesenchymal stem cells
   Exp Cell Res, 315 (15), 2558-67
   PubMed 19477173
4. Koga H, Engebretsen L, Brinchmann JE, Muneta T, Sekiya I (2009)
   Mesenchymal stem cell-based therapy for cartilage repair: a review
   Knee Surg Sports Traumatol Arthrosc, 17 (11), 1289-97
   PubMed 19333576

Publications 2008

1. Brinchmann JE (2008)
   Expanding autologous multipotent mesenchymal bone marrow stromal cells
   J Neurol Sci, 265 (1-2), 127-30
   PubMed 17560612
2. Dahl JA, Duggal S, Coulston N, Millar D, Melki J, Shahdadfar A, Brinchmann JE, Collas P (2008)
   Genetic and epigenetic instability of human bone marrow mesenchymal stem cells expanded in autologous serum or fetal bovine serum
   Int J Dev Biol, 52 (8), 1033-42
   PubMed 18956336
3. Løken S, Jakobsen RB, Arøen A, Heir S, Shahdadfar A, Brinchmann JE, Engebretsen L, Reinholt FP (2008)
   Bone marrow mesenchymal stem cells in a hyaluronan scaffold for treatment of an osteochondral defect in a rabbit model
   Knee Surg Sports Traumatol Arthrosc, 16 (10), 896-903
   PubMed 18592218
4. Shahdadfar A, Løken S, Dahl JA, Tunheim SH, Collas P, Reinholt FP, Engebretsen L, Brinchmann JE (2008)
   Persistence of collagen type II synthesis and secretion in rapidly proliferating human articular chondrocytes in vitro
   Tissue Eng Part A, 14 (12), 1999-2007
   PubMed 18636947
5. Wester T, Jørgensen JJ, Stranden E, Sandbaek G, Tjønnfjord G, Bay D, Kollerøs D, Kroese AJ, Brinchmann JE (2008)
   Treatment with autologous bone marrow mononuclear cells in patients with critical lower limb ischaemia. A pilot study
   Scand J Surg, 97 (1), 56-62
   PubMed 18450207

Publications 2007

1. Egeland T, Brinchmann JE (2007)
   Cell quality in the ASTAMI study
   Eur Heart J, 28 (17), 2172; author reply 2173-4
   PubMed 17675309
2. Egeland T, Brinchmann JE (2007)
   The REPAIR-AMI and ASTAMI trials: cell isolation procedures
   Eur Heart J, 28 (17), 2174-5; author reply 2175
   PubMed 17673446

Publications 2006

1. Boquest AC, Shahdadfar A, Brinchmann JE, Collas P (2006)
   Isolation of stromal stem cells from human adipose tissue
   Methods Mol Biol, 325, 35-46
   PubMed 16761717
2. Kvale EØ, Dalgaard J, Lund-Johansen F, Rollag H, Farkas L, Midtvedt K, Jahnsen FL, Brinchmann JE, Olweus J (2006)
   CD11c+ dendritic cells and plasmacytoid DCs are activated by human cytomegalovirus and retain efficient T cell-stimulatory capability upon infection
   Blood, 107 (5), 2022-9
   PubMed 16269620
3. Lunde K, Solheim S, Aakhus S, Arnesen H, Abdelnoor M, Egeland T, Endresen K, Ilebekk A, Mangschau A, Fjeld JG, Smith HJ, Taraldsrud E, Grøgaard HK, Bjørnerheim R, Brekke M, Müller C, Hopp E, Ragnarsson A, Brinchmann JE, Forfang K (2006)
   Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction
   N Engl J Med, 355 (12), 1199-209
   PubMed 16990383

Publications 2005

1. Boquest AC, Shahdadfar A, Frønsdal K, Sigurjonsson O, Tunheim SH, Collas P, Brinchmann JE (2005)
   Isolation and transcription profiling of purified uncultured human stromal stem cells: alteration of gene expression after in vitro cell culture
   Mol Biol Cell, 16 (3), 1131-41
   PubMed 15635089
2. Dalgaard J, Beckstrøm KJ, Jahnsen FL, Brinchmann JE (2005)
   Differential capability for phagocytosis of apoptotic and necrotic leukemia cells by human peripheral blood dendritic cell subsets
   J Leukoc Biol, 77 (5), 689-98
   PubMed 15728242
3. Hedfors IA, Beckstrøm KJ, Benati C, Bonini C, Brinchmann JE (2005)
   Retrovirus mediated gene transduction of human T-cell subsets
   Cancer Immunol Immunother, 54 (8), 759-68
   PubMed 15655695
4. Shahdadfar A, Frønsdal K, Haug T, Reinholt FP, Brinchmann JE (2005)
   In vitro expansion of human mesenchymal stem cells: choice of serum is a determinant of cell proliferation, differentiation, gene expression, and transcriptome stability
   Stem Cells, 23 (9), 1357-66
   PubMed 16081661

Publications 2004

1. Hedfors IA, Brinchmann JE (2004)
   Polyclonal T-cell activation protocol stimulates preferential expansion of EBV-specific T-cell clones in vitro
   Cancer Immunol Immunother, 53 (5), 439-44
   PubMed 14624314

Publications 2003

1. Dalgaard J, Beckstrøm KJ, Brinchmann JE (2003)
   Uptake of Apoptotic K562 Leukaemia Cells by Immature Dendritic Cells is Greatly Facilitated by Serum
   Scand J Immunol, 58 (5), 541-9
   PubMed 14629626
2. Hedfors IA, Brinchmann JE (2003)
   Long-term proliferation and survival of in vitro-activated T cells is dependent on Interleukin-2 receptor signalling but not on the high-affinity IL-2R
   Scand J Immunol, 58 (5), 522-32
   PubMed 14629624

Publications 2000

1. Brinchmann JE (2000)
   Differential responses of T cell subsets: possible role in the immunopathogenesis of AIDS
   AIDS, 14 (12), 1689-700
   PubMed 10985304

Publications 1999

1. Mugnaini EN, Egeland T, Spurkland A, Brinchmann JE (1999)
   The T cell receptor repertoire of CD8+CD28- T lymphocytes is dominated by expanded clones that persist over time
   Clin Exp Immunol, 117 (2), 298-303
   PubMed 10444261
2. Mugnaini EN, Egeland T, Syversen AM, Spurkland A, Brinchmann JE (1999)
   Molecular analysis of the complementarity determining region 3 of the human T cell receptor beta chain. Establishment of a reference panel of CDR3 lengths from phytohaemagglutinin activated lymphocytes
   J Immunol Methods, 223 (2), 207-16
   PubMed 10089099
3. Mugnaini EN, Haaheim LL, Sannes M, Brinchmann JE (1999)
   In vivo expansion coincident with excessive in vitro cell death within the memory subset of CD8+ T cells in HIV type 1 infection
   AIDS Res Hum Retroviruses, 15 (3), 265-72
   PubMed 10052757
4. Mugnaini EN, Syversen AM, Sannes M, Freng A, Brinchmann JE (1999)
   Normal CD4 T-cell receptor repertoire in tonsillar tissue despite perturbed repertoire in peripheral blood in HIV-1 infected individuals
   AIDS, 13 (18), 2507-13
   PubMed 10630519

Publications 1998

1. Brinchmann JE, Røsok BI, Spurkland A (1998)
   Activation and proliferation of CD8+ T cells in lymphoid tissues of HIV-1-infected individuals in the absence of the high-affinity IL-2 receptor
   J Acquir Immune Defic Syndr Hum Retrovirol, 19 (4), 332-8
   PubMed 9833741
2. Mugnaini EN, Spurkland A, Egeland T, Sannes M, Brinchmann JE (1998)
   Demonstration of identical expanded clones within both CD8+CD28+ and CD8+CD28- T cell subsets in HIV type 1-infected individuals
   Eur J Immunol, 28 (5), 1738-42
   PubMed 9603481
3. Reisaeter AV, Thorsby E, Brinchmann JE (1998)
   Allospecific helper T-lymphocyte repertoire in monozygotic twins
   Scand J Immunol, 47 (4), 381-7
   PubMed 9600321
4. Røsok BI, Brinchmann JE, Stent G, Bjerknes R, Voltersvik P, Olofsson J, Asjö B (1998)
   Correlates of apoptosis of CD4+ and CD8+ T cells in tonsillar tissue in HIV type 1 infection
   AIDS Res Hum Retroviruses, 14 (18), 1635-43
   PubMed 9870316
5. Spurkland A, Brinchmann JE, Markussen G, Pedeutour F, Munthe E, Lea T, Vartdal F, Aasheim HC (1998)
   Molecular cloning of a T cell-specific adapter protein (TSAd) containing an Src homology (SH) 2 domain and putative SH3 and phosphotyrosine binding sites
   J Biol Chem, 273 (8), 4539-46
   PubMed 9468509

Publications 1997

1. Rosok B, Brinchmann JE, Voltersvik P, Olofsson J, Bostad L, Asjö B (1997)
   Correlates of latent and productive HIV type-1 infection in tonsillar CD4(+) T cells
   Proc Natl Acad Sci U S A, 94 (17), 9332-6
   PubMed 9256482
2. Røsok B, Voltersvik P, Larsson BM, Albert J, Brinchmann JE, Asjö B (1997)
   CD8+ T cells from HIV type 1-seronegative individuals suppress virus replication in acutely infected cells
   AIDS Res Hum Retroviruses, 13 (1), 79-85
   PubMed 8989430

Publications 1996

1. Brinchmann JE, Janson CH, Klem LB, Haaheim LL, Spurkland A (1996)
   Strict adherence to a common rank order of T-cell receptor V beta usage in human leucocyte antigen disparate individuals
   Scand J Immunol, 44 (2), 179-84
   PubMed 8711432
2. Reisaeter AV, Brinchmann JE, Lundin KE, Thorsby E (1996)
   Monozygotic twins display differences in their allospecific cytotoxic T-cell repertoire
   Scand J Immunol, 44 (6), 638-42
   PubMed 8972747
3. Reisaeter AV, Thorsby E, Brinchmann JE (1996)
   Analysis of alloreactive helper T lymphocyte precursor frequencies. Influence of interleukin-2 produced by the stimulating cells
   J Immunol Methods, 189 (1), 65-72
   PubMed 8576581
4. Røsok BI, Bostad L, Voltersvik P, Bjerknes R, Olofsson J, Asjö B, Brinchmann JE (1996)
   Reduced CD4 cell counts in blood do not reflect CD4 cell depletion in tonsillar tissue in asymptomatic HIV-1 infection
   AIDS, 10 (10), F35-8
   PubMed 8874620

Publications 1994

1. Brinchmann JE, Dobloug JH, Heger BH, Haaheim LL, Sannes M, Egeland T (1994)
   Expression of costimulatory molecule CD28 on T cells in human immunodeficiency virus type 1 infection: functional and clinical correlations
   J Infect Dis, 169 (4), 730-8
   PubMed 7907640
2. Lundin KE, Brinchmann JE, Hansen T (1994)
   Interactions between staphylococcal superantigens and human T-cell clones are predominantly but not exclusively governed by their T-cell receptor V beta usage
   Scand J Immunol, 39 (4), 387-94
   PubMed 8146598

Publications 1992

1. Brinchmann JE (1992)
   [Factors influencing the development of the HIV pandemic]
   Tidsskr Nor Laegeforen, 112 (17), 2231-4
   PubMed 1523666
2. Brinchmann JE (1992)
   [HIV pandemic--history, present, future]
   Tidsskr Nor Laegeforen, 112 (17), 2268-71
   PubMed 1523672
3. Brinchmann JE, Gaudernack G, Thorsby E, Vartdal F (1992)
   Staphylococcal exotoxin superantigens induce human immunodeficiency virus type 1 expression in naturally infected CD4+ T cells
   J Virol, 66 (10), 5924-8
   PubMed 1356159

Publications 1991

1. Brinchmann JE, Albert J, Vartdal F (1991)
   Few infected CD4+ T cells but a high proportion of replication-competent provirus copies in asymptomatic human immunodeficiency virus type 1 infection
   J Virol, 65 (4), 2019-23
   PubMed 1672165
2. Brinchmann JE, Gaudernack G, Vartdal F (1991)
   In vitro replication of HIV-1 in naturally infected CD4+ T cells is inhibited by rIFN alpha 2 and by a soluble factor secreted by activated CD8+ T cells, but not by rIFN beta, rIFN gamma, or recombinant tumor necrosis factor-alpha
   J Acquir Immune Defic Syndr, 4 (5), 480-8
   PubMed 1673156
3. Brinchmann JE, Vartdal F, Thorsby E, Bucher A, Frøland SS, Kittelsen P, Kristoffersen J, Baklien K (1991)
   [Quantification of T-lymphocyte subpopulations. Immunological marker in human immunodeficiency virus infections]
   Tidsskr Nor Laegeforen, 111 (4), 440-3
   PubMed 2006482

Publications 1990

1. Brinchmann JE, Gaudernack G, Vartdal F (1990)
   CD8+ T cells inhibit HIV replication in naturally infected CD4+ T cells. Evidence for a soluble inhibitor
   J Immunol, 144 (8), 2961-6
   PubMed 1969879

Publications 1989

1. Brinchmann JE, Gaudernack G, Thorsby E, Jonassen TO, Vartdal F (1989)
   Reliable isolation of human immunodeficiency virus from cultures of naturally infected CD4+ T cells
   J Virol Methods, 25 (3), 293-300
   PubMed 2573612
2. Brinchmann JE, Leivestad T, Vartdal F (1989)
   Quantification of lymphocyte subsets based on positive immunomagnetic selection of cells directly from blood
   J Immunogenet, 16 (2), 177-83
   PubMed 2687388
3. Brinchmann JE, Vartdal F, Thorsby E (1989)
   T lymphocyte subset changes in human immunodeficiency virus infection
   J Acquir Immune Defic Syndr, 2 (4), 398-403
   PubMed 2526872

Publications 1988

1. Brinchmann JE, Vartdal F, Forset KL, Thorsby E (1988)
   A comparison of serial E-RFC monitoring and immunomagnetic quantitation of CD2+ cells in RATG-treated transplant recipients
   Transplantation, 45 (4), 804-5
   PubMed 2895968
2. Brinchmann JE, Vartdal F, Forset KL, Thorsby E (1988)
   Immunologic monitoring of rabbit antithymocyte globulin-treated transplant recipients: a comparison of serial E-RFC and immunomagnetic quantitation of CD2+ cells
   Transplant Proc, 20 (3), 390-1
   PubMed 3289168
3. Brinchmann JE, Vartdal F, Gaudernack G, Markussen G, Funderud S, Ugelstad J, Thorsby E (1988)
   Direct immunomagnetic quantification of lymphocyte subsets in blood
   Clin Exp Immunol, 71 (1), 182-6
   PubMed 3349645

Publications 1983

1. Brinchmann JE, Haukås G (1983)
   [Unusual manifestations of syphilis]
   Tidsskr Nor Laegeforen, 103 (13), 1058-60
   PubMed 6879544