Publications

Publications published since 1972 from OUS - Molecular Genetic Studies of Breast and Ovarian Cancer

696 publications found

Publications 2017

  1. Aure MR, Vitelli V, Jernström S, Kumar S, Krohn M, Due EU, Haukaas TH, Leivonen SK, Vollan HK, Lüders T, Rødland E, Vaske CJ, Zhao W, Møller EK, Nord S, Giskeødegård GF, Bathen TF, Caldas C, Tramm T, Alsner J, Overgaard J, Geisler J, Bukholm IR, Naume B, Schlichting E et al. (2017)
    Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome
    Breast Cancer Res, 19 (1), 44
    PubMed 28356166
  2. Byrne AT, Alférez DG, Amant F, Annibali D, Arribas J, Biankin AV, Bruna A, Budinská E, Caldas C, Chang DK, Clarke RB, Clevers H, Coukos G, Dangles-Marie V, Eckhardt SG, Gonzalez-Suarez E, Hermans E, Hidalgo M, Jarzabek MA, de Jong S, Jonkers J, Kemper K, Lanfrancone L, Mælandsmo GM, Marangoni E et al. (2017)
    Interrogating open issues in cancer precision medicine with patient-derived xenografts
    Nat Rev Cancer, 17 (4), 254-268
    PubMed 28104906
  3. Davies H, Glodzik D, Morganella S, Yates LR, Staaf J, Zou X, Ramakrishna M, Martin S, Boyault S, Sieuwerts AM, Simpson PT, King TA, Raine K, Eyfjord JE, Kong G, Borg Å, Birney E, Stunnenberg HG, van de Vijver MJ, Børresen-Dale AL, Martens JW, Span PN, Lakhani SR, Vincent-Salomon A, Sotiriou C et al. (2017)
    HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures
    Nat Med, 23 (4), 517-525
    PubMed 28288110
  4. Euceda LR, Haukaas TH, Giskeodegard GF, Vettukattil R, Engel J, Silwal-Pandit L, Lundgren S, Borgen E, Garred O, Postma G, Buydens LMC, Borresen-Dale AL, Engebraaten O, Bathen TF (2017)
    Evaluation of metabolomic changes during neoadjuvant chemotherapy combined with bevacizumab in breast cancer using MR spectroscopy
    Metabolomics, 13 (4), 37
  5. Fleischer T, Klajic J, Aure MR, Louhimo R, Pladsen AV, Ottestad L, Touleimat N, Laakso M, Halvorsen AR, Grenaker Alnæs GI, Riis ML, Helland Å, Hautaniemi S, Lønning PE, Naume B, Børresen-Dale AL, Tost J, Kristensen VN (2017)
    DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival
    Oncotarget, 8 (1), 1074-1082
    PubMed 27911866
  6. Glodzik D, Morganella S, Davies H, Simpson PT, Li Y, Zou X, Diez-Perez J, Staaf J, Alexandrov LB, Smid M, Brinkman AB, Rye IH, Russnes H, Raine K, Purdie CA, Lakhani SR, Thompson AM, Birney E, Stunnenberg HG, van de Vijver MJ, Martens JW, Børresen-Dale AL, Richardson AL, Kong G, Viari A et al. (2017)
    A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers
    Nat Genet, 49 (3), 341-348
    PubMed 28112740
  7. Jernström S, Hongisto V, Leivonen SK, Due EU, Tadele DS, Edgren H, Kallioniemi O, Perälä M, Mælandsmo GM, Sahlberg KK (2017)
    Drug-screening and genomic analyses of HER2-positive breast cancer cell lines reveal predictors for treatment response
    Breast Cancer (Dove Med Press), 9, 185-198
    PubMed 28356768
  8. Ju YS, Martincorena I, Gerstung M, Petljak M, Alexandrov LB, Rahbari R, Wedge DC, Davies HR, Ramakrishna M, Fullam A, Martin S, Alder C, Patel N, Gamble S, O'Meara S, Giri DD, Sauer T, Pinder SE, Purdie CA, Borg Å, Stunnenberg H, van de Vijver M, Tan BK, Caldas C, Tutt A et al. (2017)
    Somatic mutations reveal asymmetric cellular dynamics in the early human embryo
    Nature, 543 (7647), 714-718
    PubMed 28329761
  9. Kristensen VN (2017)
    The Antigenicity of the Tumor Cell - Context Matters
    N Engl J Med, 376 (5), 491-493
    PubMed 28146670
  10. Leroy B, Ballinger ML, Baran-Marszak F, Bond GL, Braithwaite A, Concin N, Donehower LA, El-Deiry WS, Fenaux P, Gaidano G, Langerød A, Hellstrom-Lindberg E, Iggo R, Lehmann-Che J, Mai PL, Malkin D, Moll UM, Myers JN, Nichols KE, Pospisilova S, Ashton-Prolla P, Rossi D, Savage SA, Strong LC, Tonin PN et al. (2017)
    Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice
    Cancer Res, 77 (6), 1250-1260
    PubMed 28254861
  11. Samuel N, Id Said B, Guha T, Novokmet A, Li W, Silwal-Pandit L, Børrsen-Dale AL, Langerød A, Hudson TJ, Malkin D (2017)
    Assessment of TP53 Polymorphisms and MDM2 SNP309 in Premenopausal Breast Cancer Risk
    Hum Mutat, 38 (3), 265-268
    PubMed 27957778
  12. Shimelis H, Mesman RLS, Von Nicolai C, Ehlen A, Guidugli L, Martin C, Calléja FMGR, Meeks H, Hallberg E, Hinton J, Lilyquist J, Hu C, Aalfs CM, Aittomäki K, Andrulis I, Anton-Culver H, Arndt V, Beckmann MW, Benitez J, Bogdanova NV, Bojesen SE, Bolla MK, Borresen-Dale AL, Brauch H, Brennan P et al. (2017)
    BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer
    Cancer Res, 77 (11), 2789-2799
    PubMed 28283652
  13. Silwal-Pandit L, Langerød A, Børresen-Dale AL (2017)
    TP53 Mutations in Breast and Ovarian Cancer
    Cold Spring Harb Perspect Med, 7 (1)
    PubMed 27815305
  14. Silwal-Pandit L, Nord S, von der Lippe Gythfeldt H, Møller EK, Fleischer T, Rødland E, Krohn M, Borgen E, Garred Ø, Olsen T, Vu P, Skjerven H, Fangberget A, Holmen MM, Schlichting E, Wille E, Nordberg Stokke M, Moen Vollan HK, Kristensen VN, Langerød A, Lundgren S, Wist EA, Naume B, Lingjerde OC, Borresen-Dale AL et al. (2017)
    The longitudinal transcriptional response to neoadjuvant chemotherapy with and without bevacizumab in breast cancer
    Clin Cancer Res (in press)
    PubMed 28487444

Publications 2016

  1. Cheng TH, Thompson DJ, O'Mara TA, Painter JN, Glubb DM, Flach S, Lewis A, French JD, Freeman-Mills L, Church D, Gorman M, Martin L, National Study of Endometrial Cancer Genetics Group (NSECG), Hodgson S, Webb PM, Australian National Endometrial Cancer Study Group (ANECS), Attia J, Holliday EG, McEvoy M, Scott RJ, Henders AK, Martin NG, Montgomery GW, Nyholt DR, Ahmed S et al. (2016)
    Five endometrial cancer risk loci identified through genome-wide association analysis
    Nat Genet, 48 (6), 667-74
    PubMed 27135401
  2. Couch FJ, Kuchenbaecker KB, Michailidou K, Mendoza-Fandino GA, Nord S, Lilyquist J, Olswold C, Hallberg E, Agata S, Ahsan H, Aittomäki K, Ambrosone C, Andrulis IL, Anton-Culver H, Arndt V, Arun BK, Arver B, Barile M, Barkardottir RB, Barrowdale D, Beckmann L, Beckmann MW, Benitez J, Blank SV, Blomqvist C et al. (2016)
    Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
    Nat Commun, 7, 11375
    PubMed 27117709
  3. Darabi H, Beesley J, Droit A, Kar S, Nord S, Moradi Marjaneh M, Soucy P, Michailidou K, Ghoussaini M, Fues Wahl H, Bolla MK, Wang Q, Dennis J, Alonso MR, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Benitez J, Bogdanova NV, Bojesen SE, Brauch H, Brenner H, Broeks A, Brüning T et al. (2016)
    Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs)
    Sci Rep, 6, 32512
    PubMed 27600471
  4. Demeulemeester J, Kumar P, Møller EK, Nord S, Wedge DC, Peterson A, Mathiesen RR, Fjelldal R, Zamani Esteki M, Theunis K, Fernandez Gallardo E, Grundstad AJ, Borgen E, Baumbusch LO, Børresen-Dale AL, White KP, Kristensen VN, Van Loo P, Voet T, Naume B (2016)
    Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing
    Genome Biol, 17 (1), 250
    PubMed 27931250
  5. Dominguez-Valentin M, Gras Navarro A, Rahman AM, Kumar S, Retière C, Ulvestad E, Kristensen V, Lund-Johansen M, Lie BA, Enger PØ, Njølstad G, Kristoffersen E, Lie SA, Chekenya M (2016)
    Identification of a Natural Killer Cell Receptor Allele That Prolongs Survival of Cytomegalovirus-Positive Glioblastoma Patients
    Cancer Res, 76 (18), 5326-36
    PubMed 27406829
  6. Dunning AM, Michailidou K, Kuchenbaecker KB, Thompson D, French JD, Beesley J, Healey CS, Kar S, Pooley KA, Lopez-Knowles E, Dicks E, Barrowdale D, Sinnott-Armstrong NA, Sallari RC, Hillman KM, Kaufmann S, Sivakumaran H, Moradi Marjaneh M, Lee JS, Hills M, Jarosz M, Drury S, Canisius S, Bolla MK, Dennis J et al. (2016)
    Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170
    Nat Genet, 48 (4), 374-86
    PubMed 26928228
  7. Easton DF, Lesueur F, Decker B, Michailidou K, Li J, Allen J, Luccarini C, Pooley KA, Shah M, Bolla MK, Wang Q, Dennis J, Ahmad J, Thompson ER, Damiola F, Pertesi M, Voegele C, Mebirouk N, Robinot N, Durand G, Forey N, Luben RN, Ahmed S, Aittomäki K, Anton-Culver H et al. (2016)
    No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing
    J Med Genet, 53 (5), 298-309
    PubMed 26921362
  8. Eftang LL, Klajic J, Kristensen VN, Tost J, Esbensen QY, Blom GP, Bukholm IR, Bukholm G (2016)
    GFRA3 promoter methylation may be associated with decreased postoperative survival in gastric cancer
    BMC Cancer, 16, 225
    PubMed 26984265
  9. Eide HA, Halvorsen AR, Sandhu V, Fåne A, Berg J, Haakensen VD, Kure EH, Brustugun OT, Kiserud CE, Kyte JA, Helland Å (2016)
    Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease
    Clin Transl Immunology, 5 (11), e109
    PubMed 27990285
  10. Espinoza JA, Jabeen S, Batra R, Papaleo E, Haakensen V, Timmermans Wielenga V, Møller Talman ML, Brunner N, Børresen-Dale AL, Gromov P, Helland Å, Kristensen VN, Gromova I (2016)
    Cytokine profiling of tumor interstitial fluid of the breast and its relationship with lymphocyte infiltration and clinicopathological characteristics
    Oncoimmunology, 5 (12), e1248015
    PubMed 28123884
  11. Ghoussaini M, French JD, Michailidou K, Nord S, Beesley J, Canisus S, Hillman KM, Kaufmann S, Sivakumaran H, Moradi Marjaneh M, Lee JS, Dennis J, Bolla MK, Wang Q, Dicks E, Milne RL, Hopper JL, Southey MC, Schmidt MK, Broeks A, Muir K, Lophatananon A, Fasching PA, Beckmann MW, Fletcher O et al. (2016)
    Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation
    Am J Hum Genet, 99 (4), 903-911
    PubMed 27640304
  12. Guo Y, Warren Andersen S, Shu XO, Michailidou K, Bolla MK, Wang Q, Garcia-Closas M, Milne RL, Schmidt MK, Chang-Claude J, Dunning A, Bojesen SE, Ahsan H, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bogdanova NV, Bonanni B, Børresen-Dale AL, Brand J, Brauch H et al. (2016)
    Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent
    PLoS Med, 13 (8), e1002105
    PubMed 27551723
  13. Halvorsen AR, Helland Å, Gromov P, Wielenga VT, Talman MM, Brunner N, Sandhu V, Børresen-Dale AL, Gromova I, Haakensen VD (2016)
    Profiling of microRNAs in tumor interstitial fluid of breast tumors - a novel resource to identify biomarkers for prognostic classification and detection of cancer
    Mol Oncol, 11 (2), 220-234
    PubMed 28145100
  14. Halvorsen AR, Silwal-Pandit L, Meza-Zepeda LA, Vodak D, Vu P, Sagerup C, Hovig E, Myklebost O, Børresen-Dale AL, Brustugun OT, Helland Å (2016)
    TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients
    Front Genet, 7, 85
    PubMed 27242894
  15. Hamdi Y, Soucy P, Adoue V, Michailidou K, Canisius S, Lemaçon A, Droit A, Andrulis IL, Anton-Culver H, Arndt V, Baynes C, Blomqvist C, Bogdanova NV, Bojesen SE, Bolla MK, Bonanni B, Borresen-Dale AL, Brand JS, Brauch H, Brenner H, Broeks A, Burwinkel B, Chang-Claude J, NBCS Collaborators, Couch FJ et al. (2016)
    Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21
    Oncotarget, 7 (49), 80140-80163
    PubMed 27792995
  16. Hamdi Y, Soucy P, Kuchenbaeker KB, Pastinen T, Droit A, Lemaçon A, Adlard J, Aittomäki K, Andrulis IL, Arason A, Arnold N, Arun BK, Azzollini J, Bane A, Barjhoux L, Barrowdale D, Benitez J, Berthet P, Blok MJ, Bobolis K, Bonadona V, Bonanni B, Bradbury AR, Brewer C, Buecher B et al. (2016)
    Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3
    Breast Cancer Res Treat, 161 (1), 117-134
    PubMed 27796716
  17. Haukaas TH, Euceda LR, Giskeødegård GF, Lamichhane S, Krohn M, Jernström S, Aure MR, Lingjærde OC, Schlichting E, Garred Ø, Due EU, Mills GB, Sahlberg KK, Børresen-Dale AL, Bathen TF, Oslo Breast Cancer Consortium (OSBREAC) (2016)
    Metabolic clusters of breast cancer in relation to gene- and protein expression subtypes
    Cancer Metab, 4, 12
    PubMed 27350877
  18. Horne HN, Chung CC, Zhang H, Yu K, Prokunina-Olsson L, Michailidou K, Bolla MK, Wang Q, Dennis J, Hopper JL, Southey MC, Schmidt MK, Broeks A, Muir K, Lophatananon A, Fasching PA, Beckmann MW, Fletcher O, Johnson N, Sawyer EJ, Tomlinson I, Burwinkel B, Marme F, Guénel P, Truong T et al. (2016)
    Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus
    PLoS One, 11 (8), e0160316
    PubMed 27556229
  19. Haakensen VD, Nygaard V, Greger L, Aure MR, Fromm B, Bukholm IR, Lüders T, Chin SF, Git A, Caldas C, Kristensen VN, Brazma A, Børresen-Dale AL, Hovig E, Helland Å (2016)
    Subtype-specific micro-RNA expression signatures in breast cancer progression
    Int J Cancer, 139 (5), 1117-28
    PubMed 27082076
  20. Kar SP, Beesley J, Amin Al Olama A, Michailidou K, Tyrer J, Kote-Jarai Z, Lawrenson K, Lindstrom S, Ramus SJ, Thompson DJ, ABCTB Investigators, Kibel AS, Dansonka-Mieszkowska A, Michael A, Dieffenbach AK, Gentry-Maharaj A, Whittemore AS, Wolk A, Monteiro A, Peixoto A, Kierzek A, Cox A, Rudolph A, Gonzalez-Neira A, Wu AH et al. (2016)
    Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types
    Cancer Discov, 6 (9), 1052-67
    PubMed 27432226
  21. Kaveh F, Baumbusch LO, Nebdal D, Børresen-Dale AL, Lingjærde OC, Edvardsen H, Kristensen VN, Solvang HK (2016)
    A systematic comparison of copy number alterations in four types of female cancer
    BMC Cancer, 16 (1), 913
    PubMed 27876019
  22. Kleibl Z, Kristensen VN (2016)
    Women at high risk of breast cancer: Molecular characteristics, clinical presentation and management
    Breast, 28, 136-44
    PubMed 27318168
  23. Lawrenson K, Kar S, McCue K, Kuchenbaeker K, Michailidou K, Tyrer J, Beesley J, Ramus SJ, Li Q, Delgado MK, Lee JM, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Arun BK, Arver B, Bandera EV, Barile M, Barkardottir RB, Barrowdale D, Beckmann MW, Benitez J, Berchuck A, Bisogna M et al. (2016)
    Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus
    Nat Commun, 7, 12675
    PubMed 27601076
  24. Lesurf R, Aure MR, Mørk HH, Vitelli V, Oslo Breast Cancer Research Consortium (OSBREAC), Lundgren S, Børresen-Dale AL, Kristensen V, Wärnberg F, Hallett M, Sørlie T (2016)
    Molecular Features of Subtype-Specific Progression from Ductal Carcinoma In Situ to Invasive Breast Cancer
    Cell Rep, 16 (4), 1166-79
    PubMed 27396337
  25. Liu J, Lončar I, Collée JM, Bolla MK, Dennis J, Michailidou K, Wang Q, Andrulis IL, Barile M, Beckmann MW, Behrens S, Benitez J, Blomqvist C, Boeckx B, Bogdanova NV, Bojesen SE, Brauch H, Brennan P, Brenner H, Broeks A, Burwinkel B, Chang-Claude J, Chen ST, Chenevix-Trench G, Cheng CY et al. (2016)
    rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk
    Sci Rep, 6, 36874
    PubMed 27845421
  26. Morganella S, Alexandrov LB, Glodzik D, Zou X, Davies H, Staaf J, Sieuwerts AM, Brinkman AB, Martin S, Ramakrishna M, Butler A, Kim HY, Borg Å, Sotiriou C, Futreal PA, Campbell PJ, Span PN, Van Laere S, Lakhani SR, Eyfjord JE, Thompson AM, Stunnenberg HG, van de Vijver MJ, Martens JW, Børresen-Dale AL et al. (2016)
    The topography of mutational processes in breast cancer genomes
    Nat Commun, 7, 11383
    PubMed 27136393
  27. Muranen TA, Greco D, Blomqvist C, Aittomäki K, Khan S, Hogervorst F, Verhoef S, Pharoah PDP, Dunning AM, Shah M, Luben R, Bojesen SE, Nordestgaard BG, Schoemaker M, Swerdlow A, García-Closas M, Figueroa J, Dörk T, Bogdanova NV, Hall P, Li J, Khusnutdinova E, Bermisheva M, Kristensen V, Borresen-Dale AL et al. (2016)
    Genetic modifiers of CHEK2*1100delC-associated breast cancer risk
    Genet Med, 19 (5), 599-603
    PubMed 27711073
  28. Nik-Zainal S, Davies H, Staaf J, Ramakrishna M, Glodzik D, Zou X, Martincorena I, Alexandrov LB, Martin S, Wedge DC, Van Loo P, Ju YS, Smid M, Brinkman AB, Morganella S, Aure MR, Lingjærde OC, Langerød A, Ringnér M, Ahn SM, Boyault S, Brock JE, Broeks A, Butler A, Desmedt C et al. (2016)
    Landscape of somatic mutations in 560 breast cancer whole-genome sequences
    Nature, 534 (7605), 47-54
    PubMed 27135926
  29. Painter JN, O'Mara TA, Marquart L, Webb PM, Attia J, Medland SE, Cheng T, Dennis J, Holliday EG, McEvoy M, Scott RJ, Ahmed S, Healey CS, Shah M, Gorman M, Martin L, Hodgson SV, Beckmann MW, Ekici AB, Fasching PA, Hein A, Rübner M, Czene K, Darabi H, Hall P et al. (2016)
    Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer
    Cancer Epidemiol Biomarkers Prev, 25 (11), 1503-1510
    PubMed 27550749
  30. Papp J, Kovacs ME, Matrai Z, Orosz E, Kásler M, Børresen-Dale AL, Olah E (2016)
    Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary
    Fam Cancer, 15 (1), 85-97
    PubMed 26446593
  31. Pelttari LM, Khan S, Vuorela M, Kiiski JI, Vilske S, Nevanlinna V, Ranta S, Schleutker J, Winqvist R, Kallioniemi A, Dörk T, Bogdanova NV, Figueroa J, Pharoah PD, Schmidt MK, Dunning AM, García-Closas M, Bolla MK, Dennis J, Michailidou K, Wang Q, Hopper JL, Southey MC, Rosenberg EH, Fasching PA et al. (2016)
    RAD51B in Familial Breast Cancer
    PLoS One, 11 (5), e0153788
    PubMed 27149063
  32. Pereira B, Chin SF, Rueda OM, Vollan HK, Provenzano E, Bardwell HA, Pugh M, Jones L, Russell R, Sammut SJ, Tsui DW, Liu B, Dawson SJ, Abraham J, Northen H, Peden JF, Mukherjee A, Turashvili G, Green AR, McKinney S, Oloumi A, Shah S, Rosenfeld N, Murphy L, Bentley DR et al. (2016)
    The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes
    Nat Commun, 7, 11479
    PubMed 27161491
  33. Petridis C, Brook MN, Shah V, Kohut K, Gorman P, Caneppele M, Levi D, Papouli E, Orr N, Cox A, Cross SS, Dos-Santos-Silva I, Peto J, Swerdlow A, Schoemaker MJ, Bolla MK, Wang Q, Dennis J, Michailidou K, Benitez J, González-Neira A, Tessier DC, Vincent D, Li J, Figueroa J et al. (2016)
    Genetic predisposition to ductal carcinoma in situ of the breast
    Breast Cancer Res, 18 (1), 22
    PubMed 26884359
  34. Reinertsen KV, Engebraaten O, Loge JH, Cvancarova M, Naume B, Wist E, Edvardsen H, Wille E, Bjøro T, Kiserud CE (2016)
    Fatigue During and After Breast Cancer Therapy-A Prospective Study
    J Pain Symptom Manage, 53 (3), 551-560
    PubMed 28042070
  35. Robles AI, Olsen KS, Tsui DW, Georgoulias V, Creaney J, Dobra K, Vyberg M, Minato N, Anders RA, Børresen-Dale AL, Zhou J, Sætrom P, Nielsen BS, Kirschner MB, Krokan HE, Papadimitrakopoulou V, Tsamardinos I, Røe OD (2016)
    Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway
    J Transl Med, 14 (1), 295
    PubMed 27756323
  36. Sandhu V, Wedge DC, Bowitz Lothe IM, Labori KJ, Dentro SC, Buanes T, Skrede ML, Dalsgaard AM, Munthe E, Myklebost O, Lingjærde OC, Børresen-Dale AL, Ikdahl T, Van Loo P, Nord S, Kure EH (2016)
    The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma
    Cancer Res, 76 (17), 5092-102
    PubMed 27488532
  37. Sas-Chen A, Aure MR, Leibovich L, Carvalho S, Enuka Y, Körner C, Polycarpou-Schwarz M, Lavi S, Nevo N, Kuznetsov Y, Yuan J, Azuaje F, Oslo Breast Cancer Research Consortium (OSBREAC)SauerTorillGeislerJürgenHofvindSolveigBathenTone FBorgenElinEngebråtenOlavFodstadØysteinGarredØysteinGeitvikGry AarumKåresenRolfNaumeBjørnMælandsmoGunhild MariRussnesHege GSchlichtingEllenSørlieThere, Ulitsky I, Diederichs S, Wiemann S, Yakhini Z, Kristensen VN, Børresen-Dale AL, Yarden Y (2016)
    LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer
    EMBO Mol Med, 8 (9), 1052-64
    PubMed 27485121
  38. Shi J, Zhang Y, Zheng W, Michailidou K, Ghoussaini M, Bolla MK, Wang Q, Dennis J, Lush M, Milne RL, Shu XO, Beesley J, Kar S, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Zhao Z, Guo X, Benitez J, Beeghly-Fadiel A, Blot W, Bogdanova NV, Bojesen SE, Brauch H et al. (2016)
    Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer
    Int J Cancer, 139 (6), 1303-17
    PubMed 27087578
  39. Shlien A, Raine K, Fuligni F, Arnold R, Nik-Zainal S, Dronov S, Mamanova L, Rosic A, Ju YS, Cooke SL, Ramakrishna M, Papaemmanuil E, Davies HR, Tarpey PS, Van Loo P, Wedge DC, Jones DR, Martin S, Marshall J, Anderson E, Hardy C, ICGC Breast Cancer Working Group, Oslo Breast Cancer Research Consortium, Barbashina V, Aparicio SA, Sauer T et al. (2016)
    Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer
    Cell Rep, 16 (7), 2032-46
    PubMed 27498871
  40. Smid M, Rodríguez-González FG, Sieuwerts AM, Salgado R, Prager-Van der Smissen WJ, Vlugt-Daane MV, van Galen A, Nik-Zainal S, Staaf J, Brinkman AB, van de Vijver MJ, Richardson AL, Fatima A, Berentsen K, Butler A, Martin S, Davies HR, Debets R, Gelder ME, van Deurzen CH, MacGrogan G, Van den Eynden GG, Purdie C, Thompson AM, Caldas C et al. (2016)
    Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration
    Nat Commun, 7, 12910
    PubMed 27666519
  41. Solvang HK, Frigessi A, Kaveh F, Riis ML, Lüders T, Bukholm IR, Kristensen VN, Andreassen BK (2016)
    Gene expression analysis supports tumor threshold over 2.0 cm for T-category breast cancer
    EURASIP J Bioinform Syst Biol, 2016 (1), 6
    PubMed 26900390
  42. Southey MC, Goldgar DE, Winqvist R, Pylkäs K, Couch F, Tischkowitz M, Foulkes WD, Dennis J, Michailidou K, van Rensburg EJ, Heikkinen T, Nevanlinna H, Hopper JL, Dörk T, Claes KB, Reis-Filho J, Teo ZL, Radice P, Catucci I, Peterlongo P, Tsimiklis H, Odefrey FA, Dowty JG, Schmidt MK, Broeks A et al. (2016)
    PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS
    J Med Genet, 53 (12), 800-811
    PubMed 27595995
  43. Sørlie T (2016)
    The Impact of Gene Expression Patterns in Breast Cancer
    Clin Chem, 62 (8), 1150-1
    PubMed 27022070
  44. Tekpli X, Skaug V, Bæra R, Phillips DH, Haugen A, Mollerup S (2016)
    Estrogen receptor expression and gene promoter methylation in non-small cell lung cancer - a short report
    Cell Oncol (Dordr), 39 (6), 583-589
    PubMed 27572263
  45. Tekpli X, Urbanucci A, Hashim A, Vågbø CB, Lyle R, Kringen MK, Staff AC, Dybedal I, Mills IG, Klungland A, Staerk J (2016)
    Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells
    Epigenetics Chromatin, 9, 21
    PubMed 27252783
  46. Thienpont B, Steinbacher J, Zhao H, D'Anna F, Kuchnio A, Ploumakis A, Ghesquière B, Van Dyck L, Boeckx B, Schoonjans L, Hermans E, Amant F, Kristensen VN, Koh KP, Mazzone M, Coleman ML, Carell T, Carmeliet P, Lambrechts D (2016)
    Tumour hypoxia causes DNA hypermethylation by reducing TET activity
    Nature, 537 (7618), 63-68
    PubMed 27533040
  47. Tinholt M, Sandset PM, Mowinckel MC, Garred Ø, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Jacobsen AF, Skretting G, Iversen N (2016)
    Determinants of acquired activated protein C resistance and D-dimer in breast cancer
    Thromb Res, 145, 78-83
    PubMed 27505249
  48. Wyszynski A, Hong CC, Lam K, Michailidou K, Lytle C, Yao S, Zhang Y, Bolla MK, Wang Q, Dennis J, Hopper JL, Southey MC, Schmidt MK, Broeks A, Muir K, Lophatananon A, Fasching PA, Beckmann MW, Peto J, Dos-Santos-Silva I, Sawyer EJ, Tomlinson I, Burwinkel B, Marme F, Guénel P et al. (2016)
    An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression
    Hum Mol Genet, 25 (17), 3863-3876
    PubMed 27402876
  49. Zeng C, Guo X, Long J, Kuchenbaecker KB, Droit A, Michailidou K, Ghoussaini M, Kar S, Freeman A, Hopper JL, Milne RL, Bolla MK, Wang Q, Dennis J, Agata S, Ahmed S, Aittomäki K, Andrulis IL, Anton-Culver H, Antonenkova NN, Arason A, Arndt V, Arun BK, Arver B, Bacot F et al. (2016)
    Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus
    Breast Cancer Res, 18 (1), 64
    PubMed 27459855
  50. Zhao Z, Wen W, Michailidou K, Bolla MK, Wang Q, Zhang B, Long J, Shu XO, Schmidt MK, Milne RL, García-Closas M, Chang-Claude J, Lindstrom S, Bojesen SE, Ahsan H, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Beeghly-Fadiel A, Benitez J, Blomqvist C, Bogdanova NV, Børresen-Dale AL et al. (2016)
    Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry
    Cancer Causes Control, 27 (5), 679-93
    PubMed 27053251

Publications 2015

  1. Alnaes GI, Ronneberg JA, Kristensen VN, Tost J (2015)
    Heterogeneous DNA Methylation Patterns in the GSTP1 Promoter Lead to Discordant Results between Assay Technologies and Impede Its Implementation as Epigenetic Biomarkers in Breast Cancer
    Genes (Basel), 6 (3), 878-900
    PubMed 26393654
  2. Aure MR, Jernström S, Krohn M, Vollan HK, Due EU, Rødland E, Kåresen R, Oslo Breast Cancer Research Consortium (OSBREAC), Ram P, Lu Y, Mills GB, Sahlberg KK, Børresen-Dale AL, Lingjærde OC, Kristensen VN (2015)
    Integrated analysis reveals microRNA networks coordinately expressed with key proteins in breast cancer
    Genome Med, 7 (1), 21
    PubMed 25873999
  3. Bjørklund SS, Kristensen VN, Seiler M, Kumar S, Alnæs GI, Ming Y, Kerrigan J, Naume B, Sachidanandam R, Bhanot G, Børresen-Dale AL, Ganesan S (2015)
    Expression of an estrogen-regulated variant transcript of the peroxisomal branched chain fatty acid oxidase ACOX2 in breast carcinomas
    BMC Cancer, 15, 524
    PubMed 26183823
  4. Bjaanæs MM, Fleischer T, Halvorsen AR, Daunay A, Busato F, Solberg S, Jørgensen L, Kure E, Edvardsen H, Børresen-Dale AL, Brustugun OT, Tost J, Kristensen V, Helland Å (2015)
    Genome-wide DNA methylation analyses in lung adenocarcinomas: Association with EGFR, KRAS and TP53 mutation status, gene expression and prognosis
    Mol Oncol, 10 (2), 330-43
    PubMed 26601720
  5. Borge KS, Nord S, Van Loo P, Lingjærde OC, Gunnes G, Alnæs GI, Solvang HK, Lüders T, Kristensen VN, Børresen-Dale AL, Lingaas F (2015)
    Canine Mammary Tumours Are Affected by Frequent Copy Number Aberrations, including Amplification of MYC and Loss of PTEN
    PLoS One, 10 (5), e0126371
    PubMed 25955013
  6. Borgquist S, Zhou W, Jirström K, Amini RM, Sollie T, Sørlie T, Blomqvist C, Butt S, Wärnberg F (2015)
    The prognostic role of HER2 expression in ductal breast carcinoma in situ (DCIS); a population-based cohort study
    BMC Cancer, 15, 468
    PubMed 26062614
  7. Cheng TH, Thompson D, Painter J, O'Mara T, Gorman M, Martin L, Palles C, Jones A, Buchanan DD, Ko Win A, Hopper J, Jenkins M, Lindor NM, Newcomb PA, Gallinger S, Conti D, Schumacher F, Casey G, Giles GG, Pharoah P, Peto J, Cox A, Swerdlow A, Couch F, Cunningham JM et al. (2015)
    Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1
    Sci Rep, 5, 17369
    PubMed 26621817
  8. Darabi H, McCue K, Beesley J, Michailidou K, Nord S, Kar S, Humphreys K, Thompson D, Ghoussaini M, Bolla MK, Dennis J, Wang Q, Canisius S, Scott CG, Apicella C, Hopper JL, Southey MC, Stone J, Broeks A, Schmidt MK, Scott RJ, Lophatananon A, Muir K, Beckmann MW, Ekici AB et al. (2015)
    Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression
    Am J Hum Genet, 97 (1), 22-34
    PubMed 26073781
  9. Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, Stolk L, Finucane HK, Sulem P, Bulik-Sullivan B, Esko T, Johnson AD, Elks CE, Franceschini N, He C, Altmaier E, Brody JA, Franke LL, Huffman JE, Keller MF, McArdle PF, Nutile T, Porcu E, Robino A, Rose LM et al. (2015)
    Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair EDITORIAL COMMENT
    Obstet. Gynecol. Surv., 70 (12), 758-762
  10. Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, Stolk L, Finucane HK, Sulem P, Bulik-Sullivan B, Esko T, Johnson AD, Elks CE, Franceschini N, He C, Altmaier E, Brody JA, Franke LL, Huffman JE, Keller MF, McArdle PF, Nutile T, Porcu E, Robino A, Rose LM et al. (2015)
    Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair
    Nat Genet, 47 (11), 1294-303
    PubMed 26414677
  11. Grawenda AM, Møller EK, Lam S, Repapi E, Teunisse AF, Alnæs GI, Børresen-Dale AL, Kristensen VN, Goding CR, Jochemsen AG, Edvardsen H, Bond GL (2015)
    Interaction between p53 mutation and a somatic HDMX biomarker better defines metastatic potential in breast cancer
    Cancer Res, 75 (4), 698-708
    PubMed 25649770
  12. Guo X, Long J, Zeng C, Michailidou K, Ghoussaini M, Bolla MK, Wang Q, Milne RL, Shu XO, Cai Q, Beesley J, Kar SP, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Beeghly-Fadiel A, Benitez J, Blot W, Bogdanova N, Bojesen SE, Brauch H, Brenner H, Brinton L, Broeks A et al. (2015)
    Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk
    Cancer Epidemiol Biomarkers Prev, 24 (11), 1680-91
    PubMed 26354892
  13. Győrffy B, Bottai G, Fleischer T, Munkácsy G, Budczies J, Paladini L, Børresen-Dale AL, Kristensen VN, Santarpia L (2015)
    Aberrant DNA methylation impacts gene expression and prognosis in breast cancer subtypes
    Int J Cancer, 138 (1), 87-97
    PubMed 26174627
  14. Haakensen VD, Steinfeld I, Saldova R, Shehni AA, Kifer I, Naume B, Rudd PM, Børresen-Dale AL, Yakhini Z (2015)
    Serum N-glycan analysis in breast cancer patients--Relation to tumour biology and clinical outcome
    Mol Oncol, 10 (1), 59-72
    PubMed 26321095
  15. Jabeen S, Holmboe L, Alnæs GI, Andersen AM, Hall KS, Kristensen VN (2015)
    Impact of genetic variants of RFC1, DHFR and MTHFR in osteosarcoma patients treated with high-dose methotrexate
    Pharmacogenomics J, 15 (5), 385-90
    PubMed 25778468
  16. Johnson KC, Koestler DC, Fleischer T, Chen P, Jenson EG, Marotti JD, Onega T, Kristensen VN, Christensen BC (2015)
    DNA methylation in ductal carcinoma in situ related with future development of invasive breast cancer
    Clin Epigenetics, 7, 75
    PubMed 26213588
  17. Ju YS, Tubio JM, Mifsud W, Fu B, Davies HR, Ramakrishna M, Li Y, Yates L, Gundem G, Tarpey PS, Behjati S, Papaemmanuil E, Martin S, Fullam A, Gerstung M, ICGC Prostate Cancer Working Group, ICGC Bone Cancer Working Group, ICGC Breast Cancer Working Group, Nangalia J, Green AR, Caldas C, Borg Å, Tutt A, Lee MT, van't Veer LJ et al. (2015)
    Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells
    Genome Res, 25 (6), 814-24
    PubMed 25963125
  18. Kabisch M, Lorenzo Bermejo J, Dünnebier T, Ying S, Michailidou K, Bolla MK, Wang Q, Dennis J, Shah M, Perkins BJ, Czene K, Darabi H, Eriksson M, Bojesen SE, Nordestgaard BG, Nielsen SF, Flyger H, Lambrechts D, Neven P, Peeters S, Weltens C, Couch FJ, Olson JE, Wang X, Purrington K et al. (2015)
    Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer
    Carcinogenesis, 36 (2), 256-71
    PubMed 25586992
  19. Lei J, Rudolph A, Moysich KB, Behrens S, Goode EL, Bolla MK, Dennis J, Dunning AM, Easton DF, Wang Q, Benitez J, Hopper JL, Southey MC, Schmidt MK, Broeks A, Fasching PA, Haeberle L, Peto J, Dos-Santos-Silva I, Sawyer EJ, Tomlinson I, Burwinkel B, Marmé F, Guénel P, Truong T et al. (2015)
    Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium
    Hum Genet, 135 (1), 137-54
    PubMed 26621531
  20. Lei J, Rudolph A, Moysich KB, Rafiq S, Behrens S, Goode EL, Pharoah PP, Seibold P, Fasching PA, Andrulis IL, Kristensen VN, Couch FJ, Hamann U, Hooning MJ, Nevanlinna H, Eilber U, Bolla MK, Dennis J, Wang Q, Lindblom A, Mannermaa A, Lambrechts D, García-Closas M, Hall P, Chenevix-Trench G et al. (2015)
    Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy
    Breast Cancer Res, 17, 18
    PubMed 25849327
  21. Meeks HD, Song H, Michailidou K, Bolla MK, Dennis J, Wang Q, Barrowdale D, Frost D, EMBRACE, McGuffog L, Ellis S, Feng B, Buys SS, Hopper JL, Southey MC, Tesoriero A, kConFab Investigators, James PA, Bruinsma F, Campbell IG, Australia Ovarian Cancer Study Group, Broeks A, Schmidt MK, Hogervorst FB, HEBON et al. (2015)
    BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers
    J Natl Cancer Inst, 108 (2)
    PubMed 26586665
  22. Michailidou K, Beesley J, Lindstrom S, Canisius S, Dennis J, Lush MJ, Maranian MJ, Bolla MK, Wang Q, Shah M, Perkins BJ, Czene K, Eriksson M, Darabi H, Brand JS, Bojesen SE, Nordestgaard BG, Flyger H, Nielsen SF, Rahman N, Turnbull C, BOCS, Fletcher O, Peto J, Gibson L et al. (2015)
    Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
    Nat Genet, 47 (4), 373-80
    PubMed 25751625
  23. Mäki-Jouppila JH, Pruikkonen S, Tambe MB, Aure MR, Halonen T, Salmela AL, Laine L, Børresen-Dale AL, Kallio MJ (2015)
    MicroRNA let-7b regulates genomic balance by targeting Aurora B kinase
    Mol Oncol, 9 (6), 1056-70
    PubMed 25682900
  24. Nielsen HM, How-Kit A, Guerin C, Castinetti F, Vollan HK, De Micco C, Daunay A, Taieb D, Van Loo P, Besse C, Kristensen VN, Hansen LL, Barlier A, Sebag F, Tost J (2015)
    Copy number variations alter methylation and parallel IGF2 overexpression in adrenal tumors
    Endocr Relat Cancer, 22 (6), 953-67
    PubMed 26400872
  25. Norum JH, Bergström Å, Andersson AB, Kuiper RV, Hoelzl MA, Sørlie T, Toftgård R (2015)
    A conditional transgenic mouse line for targeted expression of the stem cell marker LGR5
    Dev Biol, 404 (2), 35-48
    PubMed 26003047
  26. Orr N, Dudbridge F, Dryden N, Maguire S, Novo D, Perrakis E, Johnson N, Ghoussaini M, Hopper JL, Southey MC, Apicella C, Stone J, Schmidt MK, Broeks A, Van't Veer LJ, Hogervorst FB, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Gibson L, Aitken Z, Warren H, Sawyer E, Tomlinson I et al. (2015)
    Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2
    Hum Mol Genet, 24 (10), 2966-84
    PubMed 25652398
  27. Ovarian Cancer Association Consortium, Breast Cancer Association Consortium, and Consortium of Modifiers of BRCA1 and BRCA2, Hollestelle A, van der Baan FH, Berchuck A, Johnatty SE, Aben KK, Agnarsson BA, Aittomäki K, Alducci E, Andrulis IL, Anton-Culver H, Antonenkova NN, Antoniou AC, Apicella C, Arndt V, Arnold N, Arun BK, Arver B, Ashworth A, Australian Ovarian Cancer Study Group, Baglietto L, Balleine R, Bandera EV, Barrowdale D, Bean YT et al. (2015)
    No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer
    Gynecol Oncol, 141 (2), 386-401
    PubMed 25940428
  28. Pfister NT, Fomin V, Regunath K, Zhou JY, Zhou W, Silwal-Pandit L, Freed-Pastor WA, Laptenko O, Neo SP, Bargonetti J, Hoque M, Tian B, Gunaratne J, Engebraaten O, Manley JL, Børresen-Dale AL, Neilsen PM, Prives C (2015)
    Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells
    Genes Dev, 29 (12), 1298-315
    PubMed 26080815
  29. Pirie A, Guo Q, Kraft P, Canisius S, Eccles DM, Rahman N, Nevanlinna H, Chen C, Khan S, Tyrer J, Bolla MK, Wang Q, Dennis J, Michailidou K, Lush M, Dunning AM, Shah M, Czene K, Darabi H, Eriksson M, Lambrechts D, Weltens C, Leunen K, van Ongeval C, Nordestgaard BG et al. (2015)
    Common germline polymorphisms associated with breast cancer-specific survival
    Breast Cancer Res, 17, 58
    PubMed 25897948
  30. Potapenko IO, Lüders T, Russnes HG, Helland Å, Sørlie T, Kristensen VN, Nord S, Lingjærde OC, Børresen-Dale AL, Haakensen VD (2015)
    Glycan-related gene expression signatures in breast cancer subtypes; relation to survival
    Mol Oncol, 9 (4), 861-76
    PubMed 25655580
  31. Quigley DA, Kristensen V (2015)
    Predicting prognosis and therapeutic response from interactions between lymphocytes and tumor cells
    Mol Oncol, 9 (10), 2054-62
    PubMed 26607741
  32. Sandhu V, Bowitz Lothe IM, Labori KJ, Skrede ML, Hamfjord J, Dalsgaard AM, Buanes T, Dube G, Kale MM, Sawant S, Kulkarni-Kale U, Børresen-Dale AL, Lingjærde OC, Kure EH (2015)
    Differential expression of miRNAs in pancreatobiliary type of periampullary adenocarcinoma and its associated stroma
    Mol Oncol, 10 (2), 303-16
    PubMed 26590090
  33. Seibold P, Schmezer P, Behrens S, Michailidou K, Bolla MK, Wang Q, Flesch-Janys D, Nevanlinna H, Fagerholm R, Aittomäki K, Blomqvist C, Margolin S, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Lambrechts D, Wildiers H, Kristensen V, Alnæs GG, Nord S, Borresen-Dale AL, Hooning MJ, Hollestelle A, Jager A et al. (2015)
    A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients
    BMC Cancer, 15, 978
    PubMed 26674097
  34. Silwal-Pandit L, Russnes H, Borgen E, Skarpeteig V, Moen Vollan HK, Schlichting E, Kåresen R, Naume B, Børresen-Dale AL, Farnebo M, Langerød A (2015)
    The Sub-Cellular Localization of WRAP53 Has Prognostic Impact in Breast Cancer
    PLoS One, 10 (10), e0139965
    PubMed 26460974
  35. Skrbo N, Tenstad E, Mælandsmo GM, Sørlie T, Andersen K (2015)
    From autonomy to community; new perspectives on tumorigenicity and therapy resistance
    Cancer Treat Rev, 41 (10), 809-13
    PubMed 26519005
  36. Stone J, Thompson DJ, Dos Santos Silva I, Scott C, Tamimi RM, Lindstrom S, Kraft P, Hazra A, Li J, Eriksson L, Czene K, Hall P, Jensen M, Cunningham J, Olson JE, Purrington K, Couch FJ, Brown J, Leyland J, Warren RM, Luben RN, Khaw KT, Smith P, Wareham NJ, Jud SM et al. (2015)
    Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures
    Cancer Res, 75 (12), 2457-67
    PubMed 25862352
  37. Tinholt M, Vollan HK, Sahlberg KK, Jernström S, Kaveh F, Lingjærde OC, Kåresen R, Sauer T, Kristensen V, Børresen-Dale AL, Sandset PM, Iversen N (2015)
    Tumor expression, plasma levels and genetic polymorphisms of the coagulation inhibitor TFPI are associated with clinicopathological parameters and survival in breast cancer, in contrast to the coagulation initiator TF
    Breast Cancer Res, 17, 44
    PubMed 25882602
  38. Aakula A, Leivonen SK, Hintsanen P, Aittokallio T, Ceder Y, Børresen-Dale AL, Perälä M, Östling P, Kallioniemi O (2015)
    MicroRNA-135b regulates ERα, AR and HIF1AN and affects breast and prostate cancer cell growth
    Mol Oncol, 9 (7), 1287-300
    PubMed 25907805

Publications 2014

  1. Almendro V, Cheng YK, Randles A, Itzkovitz S, Marusyk A, Ametller E, Gonzalez-Farre X, Muñoz M, Russnes HG, Helland A, Rye IH, Borresen-Dale AL, Maruyama R, van Oudenaarden A, Dowsett M, Jones RL, Reis-Filho J, Gascon P, Gönen M, Michor F, Polyak K (2014)
    Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity
    Cell Rep, 6 (3), 514-27
    PubMed 24462293
  2. Askautrud HA, Gjernes E, Gunnes G, Sletten M, Ross DT, Børresen-Dale AL, Iversen N, Tranulis MA, Frengen E (2014)
    Global gene expression analysis reveals a link between NDRG1 and vesicle transport
    PLoS One, 9 (1), e87268
    PubMed 24498060
  3. Bjaanaes MM, Halvorsen AR, Solberg S, Jørgensen L, Dragani TA, Galvan A, Colombo F, Anderlini M, Pastorino U, Kure E, Børresen-Dale AL, Brustugun OT, Helland A (2014)
    Unique microRNA-profiles in EGFR-mutated lung adenocarcinomas
    Int J Cancer, 135 (8), 1812-21
    PubMed 24599520
  4. Carvajal-Carmona LG, O'Mara TA, Painter JN, Lose FA, Dennis J, Michailidou K, Tyrer JP, Ahmed S, Ferguson K, Healey CS, Pooley K, Beesley J, Cheng T, Jones A, Howarth K, Martin L, Gorman M, Hodgson S, National Study of Endometrial Cancer Genetics Group (NSECG), Australian National Endometrial Cancer Study Group (ANECS), Wentzensen N, Fasching PA, Hein A, Beckmann MW, Renner SP et al. (2014)
    Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk
    Hum Genet, 134 (2), 231-45
    PubMed 25487306
  5. Chaluvally-Raghavan P, Zhang F, Pradeep S, Hamilton MP, Zhao X, Rupaimoole R, Moss T, Lu Y, Yu S, Pecot CV, Aure MR, Peuget S, Rodriguez-Aguayo C, Han HD, Zhang D, Venkatanarayan A, Krohn M, Kristensen VN, Gagea M, Ram P, Liu W, Lopez-Berestein G, Lorenzi PL, Børresen-Dale AL, Chin K et al. (2014)
    Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers
    Cancer Cell, 26 (6), 863-79
    PubMed 25490449
  6. Fleischer T, Edvardsen H, Solvang HK, Daviaud C, Naume B, Børresen-Dale AL, Kristensen VN, Tost J (2014)
    Integrated analysis of high-resolution DNA methylation profiles, gene expression, germline genotypes and clinical end points in breast cancer patients
    Int J Cancer, 134 (11), 2615-25
    PubMed 24395279
  7. Fleischer T, Frigessi A, Johnson KC, Edvardsen H, Touleimat N, Klajic J, Riis ML, Haakensen VD, Wärnberg F, Naume B, Helland A, Børresen-Dale AL, Tost J, Christensen BC, Kristensen VN (2014)
    Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis
    Genome Biol, 15 (8), 435
    PubMed 25146004
  8. Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, Guo Q, Schmidt MK, Shah M, Luben R, Brown J, Czene K, Darabi H, Eriksson M, Klevebring D, Bojesen SE et al. (2014)
    Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation
    Nat Commun, 4, 4999
    PubMed 25248036
  9. Glubb DM, Maranian MJ, Michailidou K, Pooley KA, Meyer KB, Kar S, Carlebur S, O'Reilly M, Betts JA, Hillman KM, Kaufmann S, Beesley J, Canisius S, Hopper JL, Southey MC, Tsimiklis H, Apicella C, Schmidt MK, Broeks A, Hogervorst FB, van der Schoot CE, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P et al. (2014)
    Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1
    Am J Hum Genet, 96 (1), 5-20
    PubMed 25529635
  10. Grinde MT, Skrbo N, Moestue SA, Rødland EA, Borgan E, Kristian A, Sitter B, Bathen TF, Børresen-Dale AL, Mælandsmo GM, Engebraaten O, Sørlie T, Marangoni E, Gribbestad IS (2014)
    Interplay of choline metabolites and genes in patient-derived breast cancer xenografts
    Breast Cancer Res, 16 (1), R5
    PubMed 24447408
  11. Halvorsen AR, Helland A, Fleischer T, Haug KM, Grenaker Alnaes GI, Nebdal D, Syljuåsen RG, Touleimat N, Busato F, Tost J, Saetersdal AB, Børresen-Dale AL, Kristensen V, Edvardsen H (2014)
    Differential DNA methylation analysis of breast cancer reveals the impact of immune signaling in radiation therapy
    Int J Cancer, 135 (9), 2085-95
    PubMed 24658971
  12. Hongisto V, Aure MR, Mäkelä R, Sahlberg KK (2014)
    The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells - A data description
    Genom Data, 2, 249-53
    PubMed 26484103
  13. Johnson N, Dudbridge F, Orr N, Gibson L, Jones ME, Schoemaker MJ, Folkerd EJ, Haynes BP, Hopper JL, Southey MC, Dite GS, Apicella C, Schmidt MK, Broeks A, Van't Veer LJ, Atsma F, Muir K, Lophatananon A, Fasching PA, Beckmann MW, Ekici AB, Renner SP, Sawyer E, Tomlinson I, Kerin M et al. (2014)
    Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study
    Breast Cancer Res, 16 (3), R51
    PubMed 24887515
  14. Khan S, Greco D, Michailidou K, Milne RL, Muranen TA, Heikkinen T, Aaltonen K, Dennis J, Bolla MK, Liu J, Hall P, Irwanto A, Humphreys K, Li J, Czene K, Chang-Claude J, Hein R, Rudolph A, Seibold P, Flesch-Janys D, Fletcher O, Peto J, dos Santos Silva I, Johnson N, Gibson L et al. (2014)
    MicroRNA related polymorphisms and breast cancer risk
    PLoS One, 9 (11), e109973
    PubMed 25390939
  15. Klajic J, Busato F, Edvardsen H, Touleimat N, Fleischer T, Bukholm I, Børresen-Dale AL, Lønning PE, Tost J, Kristensen VN (2014)
    DNA methylation status of key cell-cycle regulators such as CDKNA2/p16 and CCNA1 correlates with treatment response to doxorubicin and 5-fluorouracil in locally advanced breast tumors
    Clin Cancer Res, 20 (24), 6357-66
    PubMed 25294903
  16. Kleivi Sahlberg K, Bottai G, Naume B, Burwinkel B, Calin GA, Børresen-Dale AL, Santarpia L (2014)
    A serum microRNA signature predicts tumor relapse and survival in triple-negative breast cancer patients
    Clin Cancer Res, 21 (5), 1207-14
    PubMed 25547678
  17. Kristensen VN, Lingjærde OC, Russnes HG, Vollan HK, Frigessi A, Børresen-Dale AL (2014)
    Principles and methods of integrative genomic analyses in cancer
    Nat Rev Cancer, 14 (5), 299-313
    PubMed 24759209
  18. Li J, Lindström LS, Foo JN, Rafiq S, Schmidt MK, Pharoah PD, Michailidou K, Dennis J, Bolla MK, Wang Q, Van 't Veer LJ, Cornelissen S, Rutgers E, Southey MC, Apicella C, Dite GS, Hopper JL, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Blomqvist C, Muranen TA, Aittomäki K, Lindblom A et al. (2014)
    2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy
    Nat Commun, 5, 4051
    PubMed 24937182
  19. Lin WY, Camp NJ, Ghoussaini M, Beesley J, Michailidou K, Hopper JL, Apicella C, Southey MC, Stone J, Schmidt MK, Broeks A, Van't Veer LJ, Th Rutgers EJ, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Peto J, Dos-Santos-Silva I, Fletcher O, Johnson N et al. (2014)
    Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk
    Hum Mol Genet, 24 (1), 285-98
    PubMed 25168388
  20. Norum JH, Andersen K, Sørlie T (2014)
    Lessons learned from the intrinsic subtypes of breast cancer in the quest for precision therapy
    Br J Surg, 101 (8), 925-38
    PubMed 24849143
  21. Nygren MK, Tekle C, Ingebrigtsen VA, Mäkelä R, Krohn M, Aure MR, Nunes-Xavier CE, Perälä M, Tramm T, Alsner J, Overgaard J, Nesland JM, Borgen E, Børresen-Dale AL, Fodstad Ø, Sahlberg KK, Leivonen SK (2014)
    Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c
    Br J Cancer, 110 (8), 2072-80
    PubMed 24577056
  22. Painter JN, O'Mara TA, Batra J, Cheng T, Lose FA, Dennis J, Michailidou K, Tyrer JP, Ahmed S, Ferguson K, Healey CS, Kaufmann S, Hillman KM, Walpole C, Moya L, Pollock P, Jones A, Howarth K, Martin L, Gorman M, Hodgson S, National Study of Endometrial Cancer Genetics Group (NSECG), CHIBCHA Consortium, De Polanco MM, Sans M et al. (2014)
    Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk
    Hum Mol Genet, 24 (5), 1478-92
    PubMed 25378557
  23. Purrington KS, Slettedahl S, Bolla MK, Michailidou K, Czene K, Nevanlinna H, Bojesen SE, Andrulis IL, Cox A, Hall P, Carpenter J, Yannoukakos D, Haiman CA, Fasching PA, Mannermaa A, Winqvist R, Brenner H, Lindblom A, Chenevix-Trench G, Benitez J, Swerdlow A, Kristensen V, Guénel P, Meindl A, Darabi H et al. (2014)
    Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade
    Hum Mol Genet, 23 (22), 6034-46
    PubMed 24927736
  24. Quigley D, Silwal-Pandit L, Dannenfelser R, Langerød A, Vollan HK, Vaske C, Siegel JU, Troyanskaya O, Chin SF, Caldas C, Balmain A, Børresen-Dale AL, Kristensen V (2014)
    Lymphocyte Invasion in IC10/Basal-Like Breast Tumors Is Associated with Wild-Type TP53
    Mol Cancer Res, 13 (3), 493-501
    PubMed 25351767
  25. Reiche K, Kasack K, Schreiber S, Lüders T, Due EU, Naume B, Riis M, Kristensen VN, Horn F, Børresen-Dale AL, Hackermüller J, Baumbusch LO (2014)
    Long non-coding RNAs differentially expressed between normal versus primary breast tumor tissues disclose converse changes to breast cancer-related protein-coding genes
    PLoS One, 9 (9), e106076
    PubMed 25264628
  26. Russnes HG, Caldas C (2014)
    eEF2K--a new target in breast cancers with combined inactivation of p53 and PTEN
    EMBO Mol Med, 6 (12), 1512-4
    PubMed 25471453
  27. Russnes HG, Lønning PE, Børresen-Dale AL, Lingjærde OC (2014)
    The multitude of molecular analyses in cancer: the opening of Pandora’s box
    Genome Biol, 15 (9), 447
    PubMed 25316146
  28. Rye IH, Lundin P, Månér S, Fjelldal R, Naume B, Wigler M, Hicks J, Børresen-Dale AL, Zetterberg A, Russnes HG (2014)
    Quantitative multigene FISH on breast carcinomas identifies der(1;16)(q10;p10) as an early event in luminal A tumors
    Genes Chromosomes Cancer, 54 (4), 235-48
    PubMed 25546585
  29. Saldova R, Asadi Shehni A, Haakensen VD, Steinfeld I, Hilliard M, Kifer I, Helland A, Yakhini Z, Børresen-Dale AL, Rudd PM (2014)
    Association of N-glycosylation with breast carcinoma and systemic features using high-resolution quantitative UPLC
    J Proteome Res, 13 (5), 2314-27
    PubMed 24669823
  30. Sandhu V, Bowitz Lothe IM, Labori KJ, Lingjærde OC, Buanes T, Dalsgaard AM, Skrede ML, Hamfjord J, Haaland T, Eide TJ, Børresen-Dale AL, Ikdahl T, Kure EH (2014)
    Molecular signatures of mRNAs and miRNAs as prognostic biomarkers in pancreatobiliary and intestinal types of periampullary adenocarcinomas
    Mol Oncol, 9 (4), 758-71
    PubMed 25579086
  31. Sawyer E, Roylance R, Petridis C, Brook MN, Nowinski S, Papouli E, Fletcher O, Pinder S, Hanby A, Kohut K, Gorman P, Caneppele M, Peto J, Dos Santos Silva I, Johnson N, Swann R, Dwek M, Perkins KA, Gillett C, Houlston R, Ross G, De Ieso P, Southey MC, Hopper JL, Provenzano E et al. (2014)
    Genetic predisposition to in situ and invasive lobular carcinoma of the breast
    PLoS Genet, 10 (4), e1004285
    PubMed 24743323
  32. Silwal-Pandit L, Vollan HK, Chin SF, Rueda OM, McKinney S, Osako T, Quigley DA, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Langerød A (2014)
    TP53 mutation spectrum in breast cancer is subtype specific and has distinct prognostic relevance
    Clin Cancer Res, 20 (13), 3569-80
    PubMed 24803582
  33. Skrbo N, Hjortland GO, Kristian A, Holm R, Nord S, Prasmickaite L, Engebraaten O, Mælandsmo GM, Sørlie T, Andersen K (2014)
    Differential in vivo tumorigenicity of distinct subpopulations from a luminal-like breast cancer xenograft
    PLoS One, 9 (11), e113278
    PubMed 25419568
  34. Sternemalm J, Russnes HG, Zhao X, Risberg B, Nord S, Caldas C, Børresen-Dale AL, Stokke T, Patzke S (2014)
    Nuclear CSPP1 expression defined subtypes of basal-like breast cancer
    Br J Cancer, 111 (2), 326-38
    PubMed 24901235
  35. Sørlie T, Johnsen H, Vu P, Lind GE, Lothe R, Børresen-Dale AL (2014)
    Mutation screening of the TP53 gene by temporal temperature gel electrophoresis (TTGE)
    Methods Mol Biol, 1105, 315-24
    PubMed 24623239
  36. Tinholt M, Viken MK, Dahm AE, Vollan HK, Sahlberg KK, Garred O, Børresen-Dale AL, Jacobsen AF, Kristensen V, Bukholm I, Kåresen R, Schlichting E, Skretting G, Lie BA, Sandset PM, Iversen N (2014)
    Increased coagulation activity and genetic polymorphisms in the F5, F10 and EPCR genes are associated with breast cancer: a case-control study
    BMC Cancer, 14, 845
    PubMed 25407022
  37. Tramm T, Kyndi M, Myhre S, Nord S, Alsner J, Sørensen FB, Sørlie T, Overgaard J (2014)
    Relationship between the prognostic and predictive value of the intrinsic subtypes and a validated gene profile predictive of loco-regional control and benefit from post-mastectomy radiotherapy in patients with high-risk breast cancer
    Acta Oncol, 53 (10), 1337-46
    PubMed 24957550
  38. Tramm T, Mohammed H, Myhre S, Kyndi M, Alsner J, Børresen-Dale AL, Sørlie T, Frigessi A, Overgaard J (2014)
    Development and validation of a gene profile predicting benefit of postmastectomy radiotherapy in patients with high-risk breast cancer: a study of gene expression in the DBCG82bc cohort
    Clin Cancer Res, 20 (20), 5272-80
    PubMed 25149560
  39. Trinh A, Rye IH, Almendro V, Helland A, Russnes HG, Markowetz F (2014)
    GoIFISH: a system for the quantification of single cell heterogeneity from IFISH images
    Genome Biol, 15 (8), 442
    PubMed 25168174
  40. Tubio JM, Li Y, Ju YS, Martincorena I, Cooke SL, Tojo M, Gundem G, Pipinikas CP, Zamora J, Raine K, Menzies A, Roman-Garcia P, Fullam A, Gerstung M, Shlien A, Tarpey PS, Papaemmanuil E, Knappskog S, Van Loo P, Ramakrishna M, Davies HR, Marshall J, Wedge DC, Teague JW, Butler AP et al. (2014)
    Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes
    Science, 345 (6196), 1251343
    PubMed 25082706
  41. Vollan HK, Rueda OM, Chin SF, Curtis C, Turashvili G, Shah S, Lingjærde OC, Yuan Y, Ng CK, Dunning MJ, Dicks E, Provenzano E, Sammut S, McKinney S, Ellis IO, Pinder S, Purushotham A, Murphy LC, Kristensen VN, METABRIC Group, Brenton JD, Pharoah PD, Børresen-Dale AL, Aparicio S, Caldas C (2014)
    A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer
    Mol Oncol, 9 (1), 115-27
    PubMed 25169931
  42. Winsel S, Mäki-Jouppila J, Tambe M, Aure MR, Pruikkonen S, Salmela AL, Halonen T, Leivonen SK, Kallio L, Børresen-Dale AL, Kallio MJ (2014)
    Excess of miRNA-378a-5p perturbs mitotic fidelity and correlates with breast cancer tumourigenesis in vivo
    Br J Cancer, 111 (11), 2142-51
    PubMed 25268374
  43. Yamamoto S, Wu Z, Russnes HG, Takagi S, Peluffo G, Vaske C, Zhao X, Moen Vollan HK, Maruyama R, Ekram MB, Sun H, Kim JH, Carver K, Zucca M, Feng J, Almendro V, Bessarabova M, Rueda OM, Nikolsky Y, Caldas C, Liu XS, Polyak K (2014)
    JARID1B is a luminal lineage-driving oncogene in breast cancer
    Cancer Cell, 25 (6), 762-77
    PubMed 24937458
  44. Zhao X, Rødland EA, Sørlie T, Vollan HK, Russnes HG, Kristensen VN, Lingjærde OC, Børresen-Dale AL (2014)
    Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status
    BMC Cancer, 14, 211
    PubMed 24645668

Publications 2013

  1. Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjörd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M et al. (2013)
    Signatures of mutational processes in human cancer
    Nature, 500 (7463), 415-21
    PubMed 23945592
  2. Aure MR, Leivonen SK, Fleischer T, Zhu Q, Overgaard J, Alsner J, Tramm T, Louhimo R, Alnæs GI, Perälä M, Busato F, Touleimat N, Tost J, Børresen-Dale AL, Hautaniemi S, Troyanskaya OG, Lingjærde OC, Sahlberg KK, Kristensen VN (2013)
    Individual and combined effects of DNA methylation and copy number alterations on miRNA expression in breast tumors
    Genome Biol, 14 (11), R126
    PubMed 24257477
  3. Aure MR, Steinfeld I, Baumbusch LO, Liestøl K, Lipson D, Nyberg S, Naume B, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Lingjærde OC, Yakhini Z (2013)
    Identifying in-trans process associated genes in breast cancer by integrated analysis of copy number and expression data
    PLoS One, 8 (1), e53014
    PubMed 23382830
  4. Baumbusch LO, Helland Å, Wang Y, Liestøl K, Schaner ME, Holm R, Etemadmoghadam D, Alsop K, Brown P, Australian Ovarian Cancer Study Group, Mitchell G, Fereday S, DeFazio A, Bowtell DD, Kristensen GB, Lingjærde OC, Børresen-Dale AL (2013)
    High levels of genomic aberrations in serous ovarian cancers are associated with better survival
    PLoS One, 8 (1), e54356
    PubMed 23372714
  5. Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, Aparicio S, Børresen-Dale AL, Caldas C, Califano A, Friend SH, Ideker T, Schadt EE, Stolovitzky GA, Margolin AA (2013)
    Improving breast cancer survival analysis through competition-based multidimensional modeling
    PLoS Comput Biol, 9 (5), e1003047
    PubMed 23671412
  6. Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE, Hillman KM, Mai PL, Lawrenson K, Stutz MD, Lu Y, Karevan R, Woods N, Johnston RL, French JD, Chen X, Weischer M, Nielsen SF, Maranian MJ, Ghoussaini M, Ahmed S et al. (2013)
    Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
    Nat Genet, 45 (4), 371-84, 384e1-2
    PubMed 23535731
  7. Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, Kaspi A, Hu R, Robens J, Nikolskaya T, Haakensen VD, Schnitt SJ, Argani P, Ethington G, Panos L, Grant M et al. (2013)
    Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics
    Cell Stem Cell, 13 (1), 117-30
    PubMed 23770079
  8. Edvardsen H, Landmark-Høyvik H, Reinertsen KV, Zhao X, Grenaker-Alnæs GI, Nebdal D, Syvänen AC, Rødningen O, Alsner J, Overgaard J, Borresen-Dale AL, Fosså SD, Kristensen VN (2013)
    SNP in TXNRD2 associated with radiation-induced fibrosis: a study of genetic variation in reactive oxygen species metabolism and signaling
    Int J Radiat Oncol Biol Phys, 86 (4), 791-9
    PubMed 23597419
  9. Engebraaten O, Vollan HK, Børresen-Dale AL (2013)
    Triple-negative breast cancer and the need for new therapeutic targets
    Am J Pathol, 183 (4), 1064-74
    PubMed 23920327
  10. French JD, Ghoussaini M, Edwards SL, Meyer KB, Michailidou K, Ahmed S, Khan S, Maranian MJ, O'Reilly M, Hillman KM, Betts JA, Carroll T, Bailey PJ, Dicks E, Beesley J, Tyrer J, Maia AT, Beck A, Knoblauch NW, Chen C, Kraft P, Barnes D, González-Neira A, Alonso MR, Herrero D et al. (2013)
    Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers
    Am J Hum Genet, 92 (4), 489-503
    PubMed 23540573
  11. Garcia-Closas M, Couch FJ, Lindstrom S, Michailidou K, Schmidt MK, Brook MN, Orr N, Rhie SK, Riboli E, Feigelson HS, Le Marchand L, Buring JE, Eccles D, Miron P, Fasching PA, Brauch H, Chang-Claude J, Carpenter J, Godwin AK, Nevanlinna H, Giles GG, Cox A, Hopper JL, Bolla MK, Wang Q et al. (2013)
    Genome-wide association studies identify four ER negative-specific breast cancer risk loci
    Nat Genet, 45 (4), 392-8, 398e1-2
    PubMed 23535733
  12. Garcia-Recio S, Fuster G, Fernandez-Nogueira P, Pastor-Arroyo EM, Park SY, Mayordomo C, Ametller E, Mancino M, Gonzalez-Farre X, Russnes HG, Engel P, Costamagna D, Fernandez PL, Gascón P, Almendro V (2013)
    Substance P autocrine signaling contributes to persistent HER2 activation that drives malignant progression and drug resistance in breast cancer
    Cancer Res, 73 (21), 6424-34
    PubMed 24030979
  13. Hongisto V, Jernström S, Fey V, Mpindi JP, Kleivi Sahlberg K, Kallioniemi O, Perälä M (2013)
    High-throughput 3D screening reveals differences in drug sensitivities between culture models of JIMT1 breast cancer cells
    PLoS One, 8 (10), e77232
    PubMed 24194875
  14. Kalous O, Conklin D, Desai AJ, Dering J, Goldstein J, Ginther C, Anderson L, Lu M, Kolarova T, Eckardt MA, Langerød A, Børresen-Dale AL, Slamon DJ, Finn RS (2013)
    AMG 900, pan-Aurora kinase inhibitor, preferentially inhibits the proliferation of breast cancer cell lines with dysfunctional p53
    Breast Cancer Res Treat, 141 (3), 397-408
    PubMed 24091768
  15. Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN (2013)
    Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors
    BMC Cancer, 13, 456
    PubMed 24093668
  16. Landmark-Høyvik H, Dumeaux V, Nebdal D, Lund E, Tost J, Kamatani Y, Renault V, Børresen-Dale AL, Kristensen V, Edvardsen H (2013)
    Genome-wide association study in breast cancer survivors reveals SNPs associated with gene expression of genes belonging to MHC class I and II
    Genomics, 102 (4), 278-87
    PubMed 23880221
  17. Leivonen SK, Sahlberg KK, Mäkelä R, Due EU, Kallioniemi O, Børresen-Dale AL, Perälä M (2013)
    High-throughput screens identify microRNAs essential for HER2 positive breast cancer cell growth
    Mol Oncol, 8 (1), 93-104
    PubMed 24148764
  18. Li J, Foo JN, Schoof N, Varghese JS, Fernandez-Navarro P, Gierach GL, Quek ST, Hartman M, Nord S, Kristensen VN, Pollán M, Figueroa JD, Thompson DJ, Li Y, Khor CC, Humphreys K, Liu J, Czene K, Hall P (2013)
    Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size
    J Med Genet, 50 (10), 666-73
    PubMed 23825393
  19. Liu Y, Zhou R, Baumbusch LO, Tsavachidis S, Brewster AM, Do KA, Sahin A, Hortobagyi GN, Taube JH, Mani SA, Aarøe J, Wärnberg F, Børresen-Dale AL, Mills GB, Thompson PA, Bondy ML (2013)
    Genomic copy number imbalances associated with bone and non-bone metastasis of early-stage breast cancer
    Breast Cancer Res Treat, 143 (1), 189-201
    PubMed 24305980
  20. Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, Schildwachter X, Russnes HG, Park D, Vang VO, Pirtle T, Youseff L, Citro C, Curtis C, Kristensen VN, Hellerstein J et al. (2013)
    Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
    Sci Transl Med, 5 (181), 181re1
    PubMed 23596205
  21. Meyer KB, O'Reilly M, Michailidou K, Carlebur S, Edwards SL, French JD, Prathalingham R, Dennis J, Bolla MK, Wang Q, de Santiago I, Hopper JL, Tsimiklis H, Apicella C, Southey MC, Schmidt MK, Broeks A, Van 't Veer LJ, Hogervorst FB, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Fasching PA, Lux MP et al. (2013)
    Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1
    Am J Hum Genet, 93 (6), 1046-60
    PubMed 24290378
  22. Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Breast and Ovarian Cancer Susceptibility Collaboration, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomäki K, Blomqvist C, Czene K et al. (2013)
    Large-scale genotyping identifies 41 new loci associated with breast cancer risk
    Nat Genet, 45 (4), 353-61, 361e1-2
    PubMed 23535729
  23. Milne RL, Herranz J, Michailidou K, Dennis J, Tyrer JP, Zamora MP, Arias-Perez JI, González-Neira A, Pita G, Alonso MR, Wang Q, Bolla MK, Czene K, Eriksson M, Humphreys K, Darabi H, Li J, Anton-Culver H, Neuhausen SL, Ziogas A, Clarke CA, Hopper JL, Dite GS, Apicella C, Southey MC et al. (2013)
    A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
    Hum Mol Genet, 23 (7), 1934-46
    PubMed 24242184
  24. Myhre S, Lingjærde OC, Hennessy BT, Aure MR, Carey MS, Alsner J, Tramm T, Overgaard J, Mills GB, Børresen-Dale AL, Sørlie T (2013)
    Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins
    Mol Oncol, 7 (3), 704-18
    PubMed 23562353
  25. Møller EK, Kumar P, Voet T, Peterson A, Van Loo P, Mathiesen RR, Fjelldal R, Grundstad J, Borgen E, Baumbusch LO, Naume B, Børresen-Dale AL, White KP, Nord S, Kristensen VN (2013)
    Next-generation sequencing of disseminated tumor cells
    Front Oncol, 3, 320
    PubMed 24427740
  26. Olaussen M, Holmedal O, Lindbaek M, Brage S, Solvang H (2013)
    Treating lateral epicondylitis with corticosteroid injections or non-electrotherapeutical physiotherapy: a systematic review
    BMJ Open, 3 (10), e003564
    PubMed 24171937
  27. Purrington KS, Slager S, Eccles D, Yannoukakos D, Fasching PA, Miron P, Carpenter J, Chang-Claude J, Martin NG, Montgomery GW, Kristensen V, Anton-Culver H, Goodfellow P, Tapper WJ, Rafiq S, Gerty SM, Durcan L, Konstantopoulou I, Fostira F, Vratimos A, Apostolou P, Konstanta I, Kotoula V, Lakis S, Dimopoulos MA et al. (2013)
    Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
    Carcinogenesis, 35 (5), 1012-9
    PubMed 24325915
  28. Quigley DA, Fiorito E, Nord S, Van Loo P, Alnæs GG, Fleischer T, Tost J, Moen Vollan HK, Tramm T, Overgaard J, Bukholm IR, Hurtado A, Balmain A, Børresen-Dale AL, Kristensen V (2013)
    The 5p12 breast cancer susceptibility locus affects MRPS30 expression in estrogen-receptor positive tumors
    Mol Oncol, 8 (2), 273-84
    PubMed 24388359
  29. Riis ML, Zhao X, Kaveh F, Vollan HS, Nesbakken AJ, Solvang HK, Lüders T, Bukholm IR, Kristensen VN (2013)
    Gene expression profile analysis of t1 and t2 breast cancer reveals different activation pathways
    ISRN Oncol, 2013, 924971
    PubMed 23533813
  30. Tahiri A, Leivonen SK, Lüders T, Steinfeld I, Ragle Aure M, Geisler J, Mäkelä R, Nord S, Riis ML, Yakhini Z, Kleivi Sahlberg K, Børresen-Dale AL, Perälä M, Bukholm IR, Kristensen VN (2013)
    Deregulation of cancer-related miRNAs is a common event in both benign and malignant human breast tumors
    Carcinogenesis, 35 (1), 76-85
    PubMed 24104550
  31. Tramm T, Hennig G, Kyndi M, Alsner J, Sørensen FB, Myhre S, Sørlie T, Overgaard J (2013)
    Reliable PCR quantitation of estrogen, progesterone and ERBB2 receptor mRNA from formalin-fixed, paraffin-embedded tissue is independent of prior macro-dissection
    Virchows Arch, 463 (6), 775-86
    PubMed 24100522
  32. Zhou W, Jirström K, Amini RM, Fjällskog ML, Sollie T, Lindman H, Sørlie T, Blomqvist C, Wärnberg F (2013)
    Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study
    BMC Cancer, 13, 512
    PubMed 24171825
  33. Zänker KS, Mihich E, Huber HP, Borresen-Dale AL (2013)
    Personalized cancer care conference
    J Pers Med, 3 (2), 70-81
    PubMed 25562519

Publications 2012

  1. Bilal E, Vassallo K, Toppmeyer D, Barnard N, Rye IH, Almendro V, Russnes H, Børresen-Dale AL, Levine AJ, Bhanot G, Ganesan S (2012)
    Amplified loci on chromosomes 8 and 17 predict early relapse in ER-positive breast cancers
    PLoS One, 7 (6), e38575
    PubMed 22719901
  2. Borgan E, Lindholm EM, Moestue S, Mælandsmo GM, Lingjærde OC, Gribbestad IS, Børresen-Dale AL, Engebraaten O, Sørlie T (2012)
    Subtype-specific response to bevacizumab is reflected in the metabolome and transcriptome of breast cancer xenografts
    Mol Oncol, 7 (1), 130-42
    PubMed 23142657
  3. Curtis C, Shah SP, Chin SF, Turashvili G, Rueda OM, Dunning MJ, Speed D, Lynch AG, Samarajiwa S, Yuan Y, Gräf S, Ha G, Haffari G, Bashashati A, Russell R, McKinney S, METABRIC Group, Langerød A, Green A, Provenzano E, Wishart G, Pinder S, Watson P, Markowetz F, Murphy L et al. (2012)
    The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
    Nature, 486 (7403), 346-52
    PubMed 22522925
  4. Engebraaten O, Edvardsen H, Løkkevik E, Naume B, Kristensen V, Ottestad L, Natarajan V (2012)
    Gefitinib in Combination with Weekly Docetaxel in Patients with Metastatic Breast Cancer Caused Unexpected Toxicity: Results from a Randomized Phase II Clinical Trial
    ISRN Oncol, 2012, 176789
    PubMed 22666610
  5. Freed-Pastor WA, Mizuno H, Zhao X, Langerød A, Moon SH, Rodriguez-Barrueco R, Barsotti A, Chicas A, Li W, Polotskaia A, Bissell MJ, Osborne TF, Tian B, Lowe SW, Silva JM, Børresen-Dale AL, Levine AJ, Bargonetti J, Prives C (2012)
    Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway
    Cell, 148 (1-2), 244-58
    PubMed 22265415
  6. Ghoussaini M, Fletcher O, Michailidou K, Turnbull C, Schmidt MK, Dicks E, Dennis J, Wang Q, Humphreys MK, Luccarini C, Baynes C, Conroy D, Maranian M, Ahmed S, Driver K, Johnson N, Orr N, dos Santos Silva I, Waisfisz Q, Meijers-Heijboer H, Uitterlinden AG, Rivadeneira F, Netherlands Collaborative Group on Hereditary Breast and Ovarian Cancer (HEBON), Hall P, Czene K et al. (2012)
    Genome-wide association analysis identifies three new breast cancer susceptibility loci
    Nat Genet, 44 (3), 312-8
    PubMed 22267197
  7. Guiu S, Michiels S, André F, Cortes J, Denkert C, Di Leo A, Hennessy BT, Sorlie T, Sotiriou C, Turner N, Van de Vijver M, Viale G, Loi S, Reis-Filho JS (2012)
    Molecular subclasses of breast cancer: how do we define them? The IMPAKT 2012 Working Group Statement
    Ann Oncol, 23 (12), 2997-3006
    PubMed 23166150
  8. Hein R, Maranian M, Hopper JL, Kapuscinski MK, Southey MC, Park DJ, Schmidt MK, Broeks A, Hogervorst FB, Bueno-de-Mesquita HB, Muir KR, Lophatananon A, Rattanamongkongul S, Puttawibul P, Fasching PA, Hein A, Ekici AB, Beckmann MW, Fletcher O, Johnson N, dos Santos Silva I, Peto J, Sawyer E, Tomlinson I, Kerin M et al. (2012)
    Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)
    PLoS One, 7 (8), e42380
    PubMed 22879957
  9. Joshi H, Bhanot G, Børresen-Dale AL, Kristensen V (2012)
    Potential tumorigenic programs associated with TP53 mutation status reveal role of VEGF pathway
    Br J Cancer, 107 (10), 1722-8
    PubMed 23079576
  10. Joshi H, Nord SH, Frigessi A, Børresen-Dale AL, Kristensen VN (2012)
    Overrepresentation of transcription factor families in the genesets underlying breast cancer subtypes
    BMC Genomics, 13, 199
    PubMed 22616941
  11. Kim J, Villadsen R, Sørlie T, Fogh L, Grønlund SZ, Fridriksdottir AJ, Kuhn I, Rank F, Wielenga VT, Solvang H, Edwards PA, Børresen-Dale AL, Rønnov-Jessen L, Bissell MJ, Petersen OW (2012)
    Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity
    Proc Natl Acad Sci U S A, 109 (16), 6124-9
    PubMed 22454501
  12. Kjersem JB, Ikdahl T, Guren T, Skovlund E, Sorbye H, Hamfjord J, Pfeiffer P, Glimelius B, Kersten C, Solvang H, Tveit KM, Kure EH (2012)
    Let-7 miRNA-binding site polymorphism in the KRAS 3'UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/- cetuximab
    BMC Cancer, 12, 534
    PubMed 23167843
  13. Lambrechts D, Truong T, Justenhoven C, Humphreys MK, Wang J, Hopper JL, Dite GS, Apicella C, Southey MC, Schmidt MK, Broeks A, Cornelissen S, van Hien R, Sawyer E, Tomlinson I, Kerin M, Miller N, Milne RL, Zamora MP, Pérez JI, Benítez J, Hamann U, Ko YD, Brüning T, GENICA Network et al. (2012)
    11q13 is a susceptibility locus for hormone receptor positive breast cancer
    Hum Mutat, 33 (7), 1123-32
    PubMed 22461340
  14. Natrajan R, Mackay A, Wilkerson PM, Lambros MB, Wetterskog D, Arnedos M, Shiu KK, Geyer FC, Langerød A, Kreike B, Reyal F, Horlings HM, van de Vijver MJ, Palacios J, Weigelt B, Reis-Filho JS (2012)
    Functional characterization of the 19q12 amplicon in grade III breast cancers
    Breast Cancer Res, 14 (2), R53
    PubMed 22433433
  15. Nerum H, Halvorsen L, Straume B, Sørlie T, Øian P (2012)
    Different labour outcomes in primiparous women that have been subjected to childhood sexual abuse or rape in adulthood: a case-control study in a clinical cohort
    BJOG, 120 (4), 487-95
    PubMed 23157417
  16. Nik-Zainal S, Alexandrov LB, Wedge DC, Van Loo P, Greenman CD, Raine K, Jones D, Hinton J, Marshall J, Stebbings LA, Menzies A, Martin S, Leung K, Chen L, Leroy C, Ramakrishna M, Rance R, Lau KW, Mudie LJ, Varela I, McBride DJ, Bignell GR, Cooke SL, Shlien A, Gamble J et al. (2012)
    Mutational processes molding the genomes of 21 breast cancers
    Cell, 149 (5), 979-93
    PubMed 22608084
  17. Nik-Zainal S, Van Loo P, Wedge DC, Alexandrov LB, Greenman CD, Lau KW, Raine K, Jones D, Marshall J, Ramakrishna M, Shlien A, Cooke SL, Hinton J, Menzies A, Stebbings LA, Leroy C, Jia M, Rance R, Mudie LJ, Gamble SJ, Stephens PJ, McLaren S, Tarpey PS, Papaemmanuil E, Davies HR et al. (2012)
    The life history of 21 breast cancers
    Cell, 149 (5), 994-1007
    PubMed 22608083
  18. Nilsen G, Liestøl K, Van Loo P, Moen Vollan HK, Eide MB, Rueda OM, Chin SF, Russell R, Baumbusch LO, Caldas C, Børresen-Dale AL, Lingjaerde OC (2012)
    Copynumber: Efficient algorithms for single- and multi-track copy number segmentation
    BMC Genomics, 13, 591
    PubMed 23442169
  19. Otto B, Gruner K, Heinlein C, Wegwitz F, Nollau P, Ylstra B, Pantel K, Schumacher U, Baumbusch LO, Martin-Subero JI, Siebert R, Wagener C, Streichert T, Deppert W, Tolstonog GV (2012)
    Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression
    Int J Cancer, 132 (6), 1300-10
    PubMed 22907219
  20. Ree AH, Kristensen AT, Saelen MG, de Wijn R, Edvardsen H, Jovanovic J, Abrahamsen TW, Dueland S, Flatmark K (2012)
    Tumor phosphatidylinositol-3-kinase signaling and development of metastatic disease in locally advanced rectal cancer
    PLoS One, 7 (11), e50806
    PubMed 23226389
  21. Riis ML, Lüders T, Markert EK, Haakensen VD, Nesbakken AJ, Kristensen VN, Bukholm IR (2012)
    Molecular profiles of pre- and postoperative breast cancer tumours reveal differentially expressed genes
    ISRN Oncol, 2012, 450267
    PubMed 23227362
  22. Sahlberg KK, Hongisto V, Edgren H, Mäkelä R, Hellström K, Due EU, Moen Vollan HK, Sahlberg N, Wolf M, Børresen-Dale AL, Perälä M, Kallioniemi O (2012)
    The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells
    Mol Oncol, 7 (3), 392-401
    PubMed 23253899
  23. Stavnes HT, Nymoen DA, Langerød A, Holth A, Børresen Dale AL, Davidson B (2012)
    AZGP1 and SPDEF mRNA expression differentiates breast carcinoma from ovarian serous carcinoma
    Virchows Arch, 462 (2), 163-73
    PubMed 23242172
  24. Stephens PJ, Tarpey PS, Davies H, Van Loo P, Greenman C, Wedge DC, Nik-Zainal S, Martin S, Varela I, Bignell GR, Yates LR, Papaemmanuil E, Beare D, Butler A, Cheverton A, Gamble J, Hinton J, Jia M, Jayakumar A, Jones D, Latimer C, Lau KW, McLaren S, McBride DJ, Menzies A et al. (2012)
    The landscape of cancer genes and mutational processes in breast cancer
    Nature, 486 (7403), 400-4
    PubMed 22722201
  25. Stevens KN, Fredericksen Z, Vachon CM, Wang X, Margolin S, Lindblom A, Nevanlinna H, Greco D, Aittomäki K, Blomqvist C, Chang-Claude J, Vrieling A, Flesch-Janys D, Sinn HP, Wang-Gohrke S, Nickels S, Brauch H, GENICA Network, Ko YD, Fischer HP, Schmutzler RK, Meindl A, Bartram CR, Schott S, Engel C et al. (2012)
    19p13.1 is a triple-negative-specific breast cancer susceptibility locus
    Cancer Res, 72 (7), 1795-803
    PubMed 22331459
  26. Synnestvedt M, Borgen E, Russnes HG, Kumar NT, Schlichting E, Giercksky KE, Kåresen R, Nesland JM, Naume B (2012)
    Combined analysis of vascular invasion, grade, HER2 and Ki67 expression identifies early breast cancer patients with questionable benefit of systemic adjuvant therapy
    Acta Oncol, 52 (1), 91-101
    PubMed 22934555
  27. Vachon CM, Scott CG, Fasching PA, Hall P, Tamimi RM, Li J, Stone J, Apicella C, Odefrey F, Gierach GL, Jud SM, Heusinger K, Beckmann MW, Pollan M, Fernández-Navarro P, Gonzalez-Neira A, Benitez J, van Gils CH, Lokate M, Onland-Moret NC, Peeters PH, Brown J, Leyland J, Varghese JS, Easton DF et al. (2012)
    Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk
    Cancer Epidemiol Biomarkers Prev, 21 (7), 1156-66
    PubMed 22454379
  28. Vaclavikova R, Ehrlichova M, Hlavata I, Pecha V, Kozevnikovova R, Trnkova M, Adamek J, Edvardsen H, Kristensen VN, Gut I, Soucek P (2012)
    Detection of frequent ABCB1 polymorphisms by high-resolution melting curve analysis and their effect on breast carcinoma prognosis
    Clin Chem Lab Med, 50 (11), 1999-2007
    PubMed 23093106
  29. Van Loo P, Nilsen G, Nordgard SH, Vollan HK, Børresen-Dale AL, Kristensen VN, Lingjærde OC (2012)
    Analyzing cancer samples with SNP arrays
    Methods Mol Biol, 802, 57-72
    PubMed 22130873
  30. Weischer M, Nordestgaard BG, Pharoah P, Bolla MK, Nevanlinna H, Van't Veer LJ, Garcia-Closas M, Hopper JL, Hall P, Andrulis IL, Devilee P, Fasching PA, Anton-Culver H, Lambrechts D, Hooning M, Cox A, Giles GG, Burwinkel B, Lindblom A, Couch FJ, Mannermaa A, Grenaker Alnæs G, John EM, Dörk T, Flyger H et al. (2012)
    CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer
    J Clin Oncol, 30 (35), 4308-16
    PubMed 23109706

Publications 2011

  1. Akslen LA, Straume O, Geisler S, Sørlie T, Chi JT, Aas T, Børresen-Dale AL, Lønning PE (2011)
    Glomeruloid microvascular proliferation is associated with lack of response to chemotherapy in breast cancer
    Br J Cancer, 105 (1), 9-12
    PubMed 21673677
  2. Borgan E, Navon R, Vollan HK, Schlichting E, Sauer T, Yakhini Z, Lingjærde OC, Sørlie T, Børresen-Dale AL (2011)
    Ischemia caused by time to freezing induces systematic microRNA and mRNA responses in cancer tissue
    Mol Oncol, 5 (6), 564-76
    PubMed 21917534
  3. Borge KS, Børresen-Dale AL, Lingaas F (2011)
    Identification of genetic variation in 11 candidate genes of canine mammary tumour
    Vet Comp Oncol, 9 (4), 241-50
    PubMed 22077404
  4. Broeks A, Schmidt MK, Sherman ME, Couch FJ, Hopper JL, Dite GS, Apicella C, Smith LD, Hammet F, Southey MC, Van 't Veer LJ, de Groot R, Smit VT, Fasching PA, Beckmann MW, Jud S, Ekici AB, Hartmann A, Hein A, Schulz-Wendtland R, Burwinkel B, Marme F, Schneeweiss A, Sinn HP, Sohn C et al. (2011)
    Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium
    Hum Mol Genet, 20 (16), 3289-303
    PubMed 21596841
  5. Dendelé B, Tekpli X, Sergent O, Dimanche-Boitrel MT, Holme JA, Huc L, Lagadic-Gossmann D (2011)
    Identification of the couple GSK3α/c-Myc as a new regulator of hexokinase II in benzo[a]pyrene-induced apoptosis
    Toxicol In Vitro, 26 (1), 94-101
    PubMed 22100782
  6. Edgren H, Murumagi A, Kangaspeska S, Nicorici D, Hongisto V, Kleivi K, Rye IH, Nyberg S, Wolf M, Borresen-Dale AL, Kallioniemi O (2011)
    Identification of fusion genes in breast cancer by paired-end RNA-sequencing
    Genome Biol, 12 (1), R6
    PubMed 21247443
  7. Enerly E, Steinfeld I, Kleivi K, Leivonen SK, Aure MR, Russnes HG, Rønneberg JA, Johnsen H, Navon R, Rødland E, Mäkelä R, Naume B, Perälä M, Kallioniemi O, Kristensen VN, Yakhini Z, Børresen-Dale AL (2011)
    miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors
    PLoS One, 6 (2), e16915
    PubMed 21364938
  8. Gonzalez-Angulo AM, Hennessy BT, Meric-Bernstam F, Sahin A, Liu W, Ju Z, Carey MS, Myhre S, Speers C, Deng L, Broaddus R, Lluch A, Aparicio S, Brown P, Pusztai L, Symmans WF, Alsner J, Overgaard J, Borresen-Dale AL, Hortobagyi GN, Coombes KR, Mills GB (2011)
    Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer
    Clin Proteomics, 8 (1), 11
    PubMed 21906370
  9. Helland Å, Anglesio MS, George J, Cowin PA, Johnstone CN, House CM, Sheppard KE, Etemadmoghadam D, Melnyk N, Rustgi AK, Phillips WA, Johnsen H, Holm R, Kristensen GB, Birrer MJ, Australian Ovarian Cancer Study Group, Pearson RB, Børresen-Dale AL, Huntsman DG, deFazio A, Creighton CJ, Smyth GK, Bowtell DD (2011)
    Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers
    PLoS One, 6 (4), e18064
    PubMed 21533284
  10. Helland Å, Skaug HM, Kleinberg L, Iversen ML, Rud AK, Fleischer T, Sagerup C, Solberg S, Jørgensen L, Ariansen S, Brustugun OT (2011)
    EGFR gene alterations in a Norwegian cohort of lung cancer patients selected for surgery
    J Thorac Oncol, 6 (5), 947-50
    PubMed 21623266
  11. Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, Wang Y, Kong B, Langerød A, Børresen-Dale AL, Kim SK, van de Vijver M, Sukumar S, Whitfield ML, Kellis M, Xiong Y, Wong DJ, Chang HY (2011)
    Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
    Nat Genet, 43 (7), 621-9
    PubMed 21642992
  12. Haakensen VD, Bjøro T, Lüders T, Riis M, Bukholm IK, Kristensen VN, Troester MA, Homen MM, Ursin G, Børresen-Dale AL, Helland Å (2011)
    Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas
    BMC Cancer, 11, 332
    PubMed 21812955
  13. Haakensen VD, Lingjaerde OC, Lüders T, Riis M, Prat A, Troester MA, Holmen MM, Frantzen JO, Romundstad L, Navjord D, Bukholm IK, Johannesen TB, Perou CM, Ursin G, Kristensen VN, Børresen-Dale AL, Helland A (2011)
    Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features
    BMC Med Genomics, 4, 77
    PubMed 22044755
  14. Kaveh F, Edvardsen H, Børresen-Dale AL, N Kristensen V, Solvang HK (2011)
    Allele-specific disparity in breast cancer
    BMC Med Genomics, 4, 85
    PubMed 22188678
  15. Knappskog S, Bjørnslett M, Myklebust LM, Huijts PE, Vreeswijk MP, Edvardsen H, Guo Y, Zhang X, Yang M, Ylisaukko-Oja SK, Alhopuro P, Arola J, Tollenaar RA, van Asperen CJ, Seynaeve C, Staalesen V, Chrisanthar R, Løkkevik E, Salvesen HB, Evans DG, Newman WG, Lin D, Aaltonen LA, Børresen-Dale AL, Tell GS et al. (2011)
    The MDM2 promoter SNP285C/309G haplotype diminishes Sp1 transcription factor binding and reduces risk for breast and ovarian cancer in Caucasians
    Cancer Cell, 19 (2), 273-82
    PubMed 21316605
  16. Kristensen VN (2011)
    Divide and conquer: the genetic basis of molecular subclassification of breast cancer
    EMBO Mol Med, 3 (4), 183-5
    PubMed 21394915
  17. Kristensen VN, Vaske CJ, Ursini-Siegel J, Van Loo P, Nordgard SH, Sachidanandam R, Sørlie T, Wärnberg F, Haakensen VD, Helland Å, Naume B, Perou CM, Haussler D, Troyanskaya OG, Børresen-Dale AL (2011)
    Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling
    Proc Natl Acad Sci U S A, 109 (8), 2802-7
    PubMed 21908711
  18. Mathiesen RR, Fjelldal R, Liestøl K, Due EU, Geigl JB, Riethdorf S, Borgen E, Rye IH, Schneider IJ, Obenauf AC, Mauermann O, Nilsen G, Christian Lingjaerde O, Børresen-Dale AL, Pantel K, Speicher MR, Naume B, Baumbusch LO (2011)
    High-resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer
    Int J Cancer, 131 (4), E405-15
    PubMed 21935921
  19. Milne RL, Goode EL, García-Closas M, Couch FJ, Severi G, Hein R, Fredericksen Z, Malats N, Zamora MP, Arias Pérez JI, Benítez J, Dörk T, Schürmann P, Karstens JH, Hillemanns P, Cox A, Brock IW, Elliot G, Cross SS, Seal S, Turnbull C, Renwick A, Rahman N, Shen CY, Yu JC et al. (2011)
    Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer
    Cancer Epidemiol Biomarkers Prev, 20 (10), 2222-31
    PubMed 21795498
  20. Molloy TJ, Bosma AJ, Baumbusch LO, Synnestvedt M, Borgen E, Russnes HG, Schlichting E, van't Veer LJ, Naume B (2011)
    The prognostic significance of tumour cell detection in the peripheral blood versus the bone marrow in 733 early-stage breast cancer patients
    Breast Cancer Res, 13 (3), R61
    PubMed 21672237
  21. Perou CM, Børresen-Dale AL (2011)
    Systems biology and genomics of breast cancer
    Cold Spring Harb Perspect Biol, 3 (2)
    PubMed 21047916
  22. Reinertsen KV, Grenaker Alnæs GI, Landmark-Høyvik H, Loge JH, Wist E, Kristensen VN, Fosså SD, Edvardsen H (2011)
    Fatigued breast cancer survivors and gene polymorphisms in the inflammatory pathway
    Brain Behav Immun, 25 (7), 1376-83
    PubMed 21496483
  23. Russnes HG, Kuligina ESh, Suspitsin EN, Voskresenskiy DA, Jordanova ES, Cornelisse CJ, Borresen-Dale AL, Imyanitov EN (2011)
    Paired distribution of molecular subtypes in bilateral breast carcinomas
    Cancer Genet, 204 (2), 96-102
    PubMed 21504707
  24. Russnes HG, Navin N, Hicks J, Borresen-Dale AL (2011)
    Insight into the heterogeneity of breast cancer through next-generation sequencing
    J Clin Invest, 121 (10), 3810-8
    PubMed 21965338
  25. Solvang HK, Lingjærde OC, Frigessi A, Børresen-Dale AL, Kristensen VN (2011)
    Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in breast cancer
    BMC Bioinformatics, 12, 197
    PubMed 21609452
  26. Sørlie T (2011)
    How to personalise treatment in early breast cancer
    Eur J Cancer, 47 Suppl 3, S310-1
    PubMed 21943994
  27. van den Broek AJ, Broeks A, Horlings HM, Canisius SV, Braaf LM, Langerød A, Van't Veer LJ, Schmidt MK (2011)
    Association of the germline TP53 R72P and MDM2 SNP309 variants with breast cancer survival in specific breast tumor subgroups
    Breast Cancer Res Treat, 130 (2), 599-608
    PubMed 21667122
  28. Weigman VJ, Chao HH, Shabalin AA, He X, Parker JS, Nordgard SH, Grushko T, Huo D, Nwachukwu C, Nobel A, Kristensen VN, Børresen-Dale AL, Olopade OI, Perou CM (2011)
    Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival
    Breast Cancer Res Treat, 133 (3), 865-80
    PubMed 22048815
  29. Westbury CB, Sahlberg KK, Borresen-Dale AL, Isacke CM, Yarnold JR (2011)
    Gene expression profiling of human dermal fibroblasts exposed to bleomycin sulphate does not differentiate between radiation sensitive and control patients
    Radiat Oncol, 6, 42
    PubMed 21521514
  30. Zhao X, Rødland EA, Sørlie T, Naume B, Langerød A, Frigessi A, Kristensen VN, Børresen-Dale AL, Lingjærde OC (2011)
    Combining gene signatures improves prediction of breast cancer survival
    PLoS One, 6 (3), e17845
    PubMed 21423775

Publications 2010

  1. Anaganti S, Fernández-Cuesta L, Langerød A, Hainaut P, Olivier M (2010)
    p53-Dependent repression of focal adhesion kinase in response to estradiol in breast cancer cell-lines
    Cancer Lett, 300 (2), 215-24
    PubMed 21071137
  2. Avraham R, Sas-Chen A, Manor O, Steinfeld I, Shalgi R, Tarcic G, Bossel N, Zeisel A, Amit I, Zwang Y, Enerly E, Russnes HG, Biagioni F, Mottolese M, Strano S, Blandino G, Børresen-Dale AL, Pilpel Y, Yakhini Z, Segal E, Yarden Y (2010)
    EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors
    Sci Signal, 3 (124), ra43
    PubMed 20516477
  3. Berge EO, Knappskog S, Geisler S, Staalesen V, Pacal M, Børresen-Dale AL, Puntervoll P, Lillehaug JR, Lønning PE (2010)
    Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers
    Mol Cancer, 9, 173
    PubMed 20594292
  4. Bernstein JL, Haile RW, Stovall M, Boice JD, Shore RE, Langholz B, Thomas DC, Bernstein L, Lynch CF, Olsen JH, Malone KE, Mellemkjaer L, Borresen-Dale AL, Rosenstein BS, Teraoka SN, Diep AT, Smith SA, Capanu M, Reiner AS, Liang X, Gatti RA, Concannon P, WECARE Study Collaborative Group (2010)
    Radiation exposure, the ATM Gene, and contralateral breast cancer in the women's environmental cancer and radiation epidemiology study
    J Natl Cancer Inst, 102 (7), 475-83
    PubMed 20305132
  5. Biong M, Gram IT, Brill I, Johansen F, Solvang HK, Alnaes GI, Fagerheim T, Bremnes Y, Chanock SJ, Burdett L, Yeager M, Ursin G, Kristensen VN (2010)
    Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density
    BMC Med Genomics, 3, 9
    PubMed 20302654
  6. Borg A, Haile RW, Malone KE, Capanu M, Diep A, Törngren T, Teraoka S, Begg CB, Thomas DC, Concannon P, Mellemkjaer L, Bernstein L, Tellhed L, Xue S, Olson ER, Liang X, Dolle J, Børresen-Dale AL, Bernstein JL (2010)
    Characterization of BRCA1 and BRCA2 deleterious mutations and variants of unknown clinical significance in unilateral and bilateral breast cancer: the WECARE study
    Hum Mutat, 31 (3), E1200-40
    PubMed 20104584
  7. Borgan E, Sitter B, Lingjærde OC, Johnsen H, Lundgren S, Bathen TF, Sørlie T, Børresen-Dale AL, Gribbestad IS (2010)
    Merging transcriptomics and metabolomics--advances in breast cancer profiling
    BMC Cancer, 10, 628
    PubMed 21080935
  8. Borresen-Dale AL (2010)
    Europe's largest Member Association for Cancer Research
    Period. Biol., 112 (4), 483-485
  9. Børresen-Dale AL, Sørlie T, Kristensen VN (2010)
    On the molecular biology of breast cancer
    Mol Oncol, 4 (3), 171-3
    PubMed 20483673
  10. de Neergaard M, Kim J, Villadsen R, Fridriksdottir AJ, Rank F, Timmermans-Wielenga V, Langerød A, Børresen-Dale AL, Petersen OW, Rønnov-Jessen L (2010)
    Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment
    Am J Pathol, 176 (3), 1229-40
    PubMed 20133812
  11. Dejeux E, Rønneberg JA, Solvang H, Bukholm I, Geisler S, Aas T, Gut IG, Børresen-Dale AL, Lønning PE, Kristensen VN, Tost J (2010)
    DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response
    Mol Cancer, 9, 68
    PubMed 20338046
  12. Dumeaux V, Olsen KS, Nuel G, Paulssen RH, Børresen-Dale AL, Lund E (2010)
    Deciphering normal blood gene expression variation--The NOWAC postgenome study
    PLoS Genet, 6 (3), e1000873
    PubMed 20300640
  13. Edvardsen H, Brunsvig PF, Solvang H, Tsalenko A, Andersen A, Syvanen AC, Yakhini Z, Børresen-Dale AL, Olsen H, Aamdal S, Kristensen VN (2010)
    SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance
    Pharmacogenomics J, 10 (6), 513-23
    PubMed 20157331
  14. Fu YP, Edvardsen H, Kaushiva A, Arhancet JP, Howe TM, Kohaar I, Porter-Gill P, Shah A, Landmark-Høyvik H, Fosså SD, Ambs S, Naume B, Børresen-Dale AL, Kristensen VN, Prokunina-Olsson L (2010)
    NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations
    Mol Cancer, 9, 113
    PubMed 20482849
  15. Hennessy BT, Lu Y, Gonzalez-Angulo AM, Carey MS, Myhre S, Ju Z, Davies MA, Liu W, Coombes K, Meric-Bernstam F, Bedrosian I, McGahren M, Agarwal R, Zhang F, Overgaard J, Alsner J, Neve RM, Kuo WL, Gray JW, Borresen-Dale AL, Mills GB (2010)
    A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers
    Clin Proteomics, 6 (4), 129-51
    PubMed 21691416
  16. Holstege H, Horlings HM, Velds A, Langerød A, Børresen-Dale AL, van de Vijver MJ, Nederlof PM, Jonkers J (2010)
    BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations
    BMC Cancer, 10, 654
    PubMed 21118481
  17. Haakensen VD, Biong M, Lingjærde OC, Holmen MM, Frantzen JO, Chen Y, Navjord D, Romundstad L, Lüders T, Bukholm IK, Solvang HK, Kristensen VN, Ursin G, Børresen-Dale AL, Helland A (2010)
    Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density
    Breast Cancer Res, 12 (4), R65
    PubMed 20799965
  18. International Cancer Genome Consortium, Hudson TJ, Anderson W, Artez A, Barker AD, Bell C, Bernabé RR, Bhan MK, Calvo F, Eerola I, Gerhard DS, Guttmacher A, Guyer M, Hemsley FM, Jennings JL, Kerr D, Klatt P, Kolar P, Kusada J, Lane DP, Laplace F, Youyong L, Nettekoven G, Ozenberger B, Peterson J et al. (2010)
    International network of cancer genome projects
    Nature, 464 (7291), 993-8
    PubMed 20393554
  19. Jovanovic J, Rønneberg JA, Tost J, Kristensen V (2010)
    The epigenetics of breast cancer
    Mol Oncol, 4 (3), 242-54
    PubMed 20627830
  20. Kamalakaran S, Varadan V, Giercksky Russnes HE, Levy D, Kendall J, Janevski A, Riggs M, Banerjee N, Synnestvedt M, Schlichting E, Kåresen R, Shama Prasada K, Rotti H, Rao R, Rao L, Eric Tang MH, Satyamoorthy K, Lucito R, Wigler M, Dimitrova N, Naume B, Borresen-Dale AL, Hicks JB (2010)
    DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables
    Mol Oncol, 5 (1), 77-92
    PubMed 21169070
  21. Kristensen V, Borresen-Dale AL (2010)
    Mutations for the people
    EMBO Mol Med, 2 (5), 143-5
    PubMed 20461736
  22. Landmark-Høyvik H, Dumeaux V, Reinertsen KV, Edvardsen H, Fosså SD, Børresen-Dale AL (2010)
    Blood gene expression profiling of breast cancer survivors experiencing fibrosis
    Int J Radiat Oncol Biol Phys, 79 (3), 875-83
    PubMed 21129856
  23. Landmark-Høyvik H, Reinertsen KV, Loge JH, Kristensen VN, Dumeaux V, Fosså SD, Børresen-Dale AL, Edvardsen H (2010)
    The genetics and epigenetics of fatigue
    PM R, 2 (5), 456-65
    PubMed 20656628
  24. Moestue SA, Borgan E, Huuse EM, Lindholm EM, Sitter B, Børresen-Dale AL, Engebraaten O, Maelandsmo GM, Gribbestad IS (2010)
    Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models
    BMC Cancer, 10, 433
    PubMed 20716336
  25. Muggerud AA, Hallett M, Johnsen H, Kleivi K, Zhou W, Tahmasebpoor S, Amini RM, Botling J, Børresen-Dale AL, Sørlie T, Wärnberg F (2010)
    Molecular diversity in ductal carcinoma in situ (DCIS) and early invasive breast cancer
    Mol Oncol, 4 (4), 357-68
    PubMed 20663721
  26. Muggerud AA, Rønneberg JA, Wärnberg F, Botling J, Busato F, Jovanovic J, Solvang H, Bukholm I, Børresen-Dale AL, Kristensen VN, Sørlie T, Tost J (2010)
    Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer
    Breast Cancer Res, 12 (1), R3
    PubMed 20056007
  27. Myhre S, Mohammed H, Tramm T, Alsner J, Finak G, Park M, Overgaard J, Børresen-Dale AL, Frigessi A, Sørlie T (2010)
    In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome
    PLoS One, 5 (11), e14002
    PubMed 21124964
  28. Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Stromberg M, Wiedswang G, Kvalheim G, Karesen R, Nesland JM, Borresen-Dale AL, Sorlie T (2010)
    Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer (vol 1, pg 160, 2007)
    Mol. Oncol., 4 (2), 169
  29. Papp J, Kovacs ME, Solyom S, Kasler M, Børresen-Dale AL, Olah E (2010)
    High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients
    BMC Med Genet, 11, 169
    PubMed 21118512
  30. Pedersen RS, Brasch-Andersen C, Sim SC, Bergmann TK, Halling J, Petersen MS, Weihe P, Edvardsen H, Kristensen VN, Brøsen K, Ingelman-Sundberg M (2010)
    Linkage disequilibrium between the CYP2C19*17 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations
    Eur J Clin Pharmacol, 66 (12), 1199-205
    PubMed 20665013
  31. Podo F, Buydens LM, Degani H, Hilhorst R, Klipp E, Gribbestad IS, Van Huffel S, van Laarhoven HW, Luts J, Monleon D, Postma GJ, Schneiderhan-Marra N, Santoro F, Wouters H, Russnes HG, Sørlie T, Tagliabue E, Børresen-Dale AL, FEMME Consortium (2010)
    Triple-negative breast cancer: present challenges and new perspectives
    Mol Oncol, 4 (3), 209-29
    PubMed 20537966
  32. Rantala JK, Edgren H, Lehtinen L, Wolf M, Kleivi K, Vollan HK, Aaltola AR, Laasola P, Kilpinen S, Saviranta P, Iljin K, Kallioniemi O (2010)
    Integrative functional genomics analysis of sustained polyploidy phenotypes in breast cancer cells identifies an oncogenic profile for GINS2
    Neoplasia, 12 (11), 877-88
    PubMed 21082043
  33. Rebillard A, Jouan-Lanhouet S, Jouan E, Legembre P, Pizon M, Sergent O, Gilot D, Tekpli X, Lagadic-Gossmann D, Dimanche-Boitrel MT (2010)
    Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells
    Eur J Cancer, 46 (8), 1445-55
    PubMed 20202822
  34. Reinertsen KV, Cvancarova M, Loge JH, Edvardsen H, Wist E, Fosså SD (2010)
    Predictors and course of chronic fatigue in long-term breast cancer survivors
    J Cancer Surviv, 4 (4), 405-14
    PubMed 20862614
  35. Russnes HG, Vollan HK, Lingjaerde OC, Krasnitz A, Lundin P, Naume B, Sørlie T, Borgen E, Rye IH, Langerød A, Chin SF, Teschendorff AE, Stephens PJ, Månér S, Schlichting E, Baumbusch LO, Kåresen R, Stratton MP, Wigler M, Caldas C, Zetterberg A, Hicks J, Børresen-Dale AL (2010)
    Genomic architecture characterizes tumor progression paths and fate in breast cancer patients
    Sci Transl Med, 2 (38), 38ra47
    PubMed 20592421
  36. Rønneberg JA, Fleischer T, Solvang HK, Nordgard SH, Edvardsen H, Potapenko I, Nebdal D, Daviaud C, Gut I, Bukholm I, Naume B, Børresen-Dale AL, Tost J, Kristensen V (2010)
    Methylation profiling with a panel of cancer related genes: association with estrogen receptor, TP53 mutation status and expression subtypes in sporadic breast cancer
    Mol Oncol, 5 (1), 61-76
    PubMed 21212030
  37. Sørlie T, Borgan E, Myhre S, Vollan HK, Russnes H, Zhao X, Nilsen G, Lingjaerde OC, Børresen-Dale AL, Rødland E (2010)
    The importance of gene-centring microarray data
    Lancet Oncol, 11 (8), 719-20; author reply 720-1
    PubMed 20688275
  38. Van Loo P, Nordgard SH, Lingjærde OC, Russnes HG, Rye IH, Sun W, Weigman VJ, Marynen P, Zetterberg A, Naume B, Perou CM, Børresen-Dale AL, Kristensen VN (2010)
    Allele-specific copy number analysis of tumors
    Proc Natl Acad Sci U S A, 107 (39), 16910-5
    PubMed 20837533
  39. Aarøe J, Lindahl T, Dumeaux V, Saebø S, Tobin D, Hagen N, Skaane P, Lönneborg A, Sharma P, Børresen-Dale AL (2010)
    Gene expression profiling of peripheral blood cells for early detection of breast cancer
    Breast Cancer Res, 12 (1), R7
    PubMed 20078854

Publications 2009

  1. Agarwal R, Gonzalez-Angulo AM, Myhre S, Carey M, Lee JS, Overgaard J, Alsner J, Stemke-Hale K, Lluch A, Neve RM, Kuo WL, Sorlie T, Sahin A, Valero V, Keyomarsi K, Gray JW, Borresen-Dale AL, Mills GB, Hennessy BT (2009)
    Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer
    Clin Cancer Res, 15 (11), 3654-62
    PubMed 19470724
  2. Asare N, Tekpli X, Rissel M, Solhaug A, Landvik N, Lecureur V, Podechard N, Brunborg G, Låg M, Lagadic-Gossmann D, Holme JA (2009)
    Signalling pathways involved in 1-nitropyrene (1-NP)-induced and 3-nitrofluoranthene (3-NF)-induced cell death in Hepa1c1c7 cells
    Mutagenesis, 24 (6), 481-93
    PubMed 19703935
  3. Beauchamp E, Tekpli X, Marteil G, Lagadic-Gossmann D, Legrand P, Rioux V (2009)
    N-Myristoylation targets dihydroceramide Delta4-desaturase 1 to mitochondria: partial involvement in the apoptotic effect of myristic acid
    Biochimie, 91 (11-12), 1411-9
    PubMed 19647031
  4. Bergamaschi A, Hjortland GO, Triulzi T, Sørlie T, Johnsen H, Ree AH, Russnes HG, Tronnes S, Maelandsmo GM, Fodstad O, Borresen-Dale AL, Engebraaten O (2009)
    Molecular profiling and characterization of luminal-like and basal-like in vivo breast cancer xenograft models
    Mol Oncol, 3 (5-6), 469-82
    PubMed 19713161
  5. Bocanegra M, Bergamaschi A, Kim YH, Miller MA, Rajput AB, Kao J, Langerød A, Han W, Noh DY, Jeffrey SS, Huntsman DG, Børresen-Dale AL, Pollack JR (2009)
    Focal amplification and oncogene dependency of GAB2 in breast cancer
    Oncogene, 29 (5), 774-9
    PubMed 19881546
  6. Dunning AM, Healey CS, Baynes C, Maia AT, Scollen S, Vega A, Rodríguez R, Barbosa-Morais NL, Ponder BA, SEARCH, Low YL, Bingham S, EPIC, Haiman CA, Le Marchand L, MEC, Broeks A, Schmidt MK, ABCS, Hopper J, Southey M, ABCFS, Beckmann MW, Fasching PA, BBCC et al. (2009)
    Association of ESR1 gene tagging SNPs with breast cancer risk
    Hum Mol Genet, 18 (6), 1131-9
    PubMed 19126777
  7. Figueiredo JC, Haile RW, Bernstein L, Malone KE, Largent J, Langholz B, Lynch CF, Bertelsen L, Capanu M, Concannon P, Borg A, Børresen-Dale AL, Diep A, Teraoka S, Torngren T, Xue S, Bernstein JL (2009)
    Oral contraceptives and postmenopausal hormones and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers and noncarriers: the WECARE Study
    Breast Cancer Res Treat, 120 (1), 175-83
    PubMed 19597986
  8. Gaudet MM, Milne RL, Cox A, Camp NJ, Goode EL, Humphreys MK, Dunning AM, Morrison J, Giles GG, Severi G, Baglietto L, English DR, Couch FJ, Olson JE, Wang X, Chang-Claude J, Flesch-Janys D, Abbas S, Salazar R, Mannermaa A, Kataja V, Kosma VM, Lindblom A, Margolin S, Heikkinen T et al. (2009)
    Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium
    Cancer Epidemiol Biomarkers Prev, 18 (5), 1610-6
    PubMed 19423537
  9. Geigl JB, Obenauf AC, Waldispuehl-Geigl J, Hoffmann EM, Auer M, Hörmann M, Fischer M, Trajanoski Z, Schenk MA, Baumbusch LO, Speicher MR (2009)
    Identification of small gains and losses in single cells after whole genome amplification on tiling oligo arrays
    Nucleic Acids Res, 37 (15), e105
    PubMed 19541849
  10. Glynn SA, Boersma BJ, Howe TM, Edvardsen H, Geisler SB, Goodman JE, Ridnour LA, Lønning PE, Børresen-Dale AL, Naume B, Kristensen VN, Chanock SJ, Wink DA, Ambs S (2009)
    A mitochondrial target sequence polymorphism in manganese superoxide dismutase predicts inferior survival in breast cancer patients treated with cyclophosphamide
    Clin Cancer Res, 15 (12), 4165-73
    PubMed 19509150
  11. Kamalakaran S, Kendall J, Zhao X, Tang C, Khan S, Ravi K, Auletta T, Riggs M, Wang Y, Helland A, Naume B, Dimitrova N, Børresen-Dale AL, Hicks J, Lucito R (2009)
    Methylation detection oligonucleotide microarray analysis: a high-resolution method for detection of CpG island methylation
    Nucleic Acids Res, 37 (12), e89
    PubMed 19474344
  12. Kraggerud SM, Oldenburg J, Alnaes GI, Berg M, Kristensen VN, Fossa SD, Lothe RA (2009)
    Functional glutathione S-transferase genotypes among testicular germ cell tumor survivors: associations with primary and post-chemotherapy tumor histology
    Pharmacogenet Genomics, 19 (10), 751-9
    PubMed 19741569
  13. Landmark-Høyvik H, Reinertsen KV, Loge JH, Fosså SD, Børresen-Dale AL, Dumeaux V (2009)
    Alterations of gene expression in blood cells associated with chronic fatigue in breast cancer survivors
    Pharmacogenomics J, 9 (5), 333-40
    PubMed 19546881
  14. Leivonen SK, Mäkelä R, Ostling P, Kohonen P, Haapa-Paananen S, Kleivi K, Enerly E, Aakula A, Hellström K, Sahlberg N, Kristensen VN, Børresen-Dale AL, Saviranta P, Perälä M, Kallioniemi O (2009)
    Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines
    Oncogene, 28 (44), 3926-36
    PubMed 19684618
  15. Lönneborg A, Aarøe J, Dumeaux V, Børresen-Dale AL (2009)
    Found in transcription: gene expression and other novel blood biomarkers for the early detection of breast cancer
    Expert Rev Anticancer Ther, 9 (8), 1115-23
    PubMed 19671031
  16. Muggerud AA, Edgren H, Wolf M, Kleivi K, Dejeux E, Tost J, Sørlie T, Kallioniemi O (2009)
    Data integration from two microarray platforms identifies bi-allelic genetic inactivation of RIC8A in a breast cancer cell line
    BMC Med Genomics, 2, 26
    PubMed 19432969
  17. Murph MM, Liu W, Yu S, Lu Y, Hall H, Hennessy BT, Lahad J, Schaner M, Helland A, Kristensen G, Børresen-Dale AL, Mills GB (2009)
    Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis
    PLoS One, 4 (5), e5583
    PubMed 19440550
  18. Olivier M, Petitjean A, Teague J, Forbes S, Dunnick JK, den Dunnen JT, Langerød A, Wilkinson JM, Vihinen M, Cotton RG, Hainaut P, IARC, EC FP6 (2009)
    Somatic mutation databases as tools for molecular epidemiology and molecular pathology of cancer: proposed guidelines for improving data collection, distribution, and integration
    Hum Mutat, 30 (3), 275-82
    PubMed 19006239
  19. Potapenko IO, Haakensen VD, Lüders T, Helland A, Bukholm I, Sørlie T, Kristensen VN, Lingjaerde OC, Børresen-Dale AL (2009)
    Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression
    Mol Oncol, 4 (2), 98-118
    PubMed 20060370
  20. Prescott TE, Rødningen OK, Bjørnstad A, Stray-Pedersen A (2009)
    Two brothers with a microduplication including the MECP2 gene: rapid head growth in infancy and resolution of susceptibility to infection
    Clin Dysmorphol, 18 (2), 78-82
    PubMed 19057379
  21. Skinningsrud B, Husebye ES, Gilfillan GD, Frengen E, Erichsen A, Gervin K, Ormerod E, Egeland T, Undlien DE (2009)
    X-linked congenital adrenal hypoplasia with hypogonadotropic hypogonadism caused by an inversion disrupting a conserved noncoding element upstream of the NR0B1 (DAX1) gene
    J Clin Endocrinol Metab, 94 (10), 4086-93
    PubMed 19773398
  22. Solvang HK, Nagahara Y, Araki S, Sawada H, Makino S (2009)
    Frequency-Domain Pearson Distribution Approach for Independent Component Analysis (FD-Pearson-ICA) in Blind Source Separation
    IEEE Trans. Audio Speech Lang. Process., 17 (4), 639-649
  23. Stephens PJ, McBride DJ, Lin ML, Varela I, Pleasance ED, Simpson JT, Stebbings LA, Leroy C, Edkins S, Mudie LJ, Greenman CD, Jia M, Latimer C, Teague JW, Lau KW, Burton J, Quail MA, Swerdlow H, Churcher C, Natrajan R, Sieuwerts AM, Martens JW, Silver DP, Langerød A, Russnes HE et al. (2009)
    Complex landscapes of somatic rearrangement in human breast cancer genomes
    Nature, 462 (7276), 1005-10
    PubMed 20033038
  24. Sun W, Wright FA, Tang Z, Nordgard SH, Van Loo P, Yu T, Kristensen VN, Perou CM (2009)
    Integrated study of copy number states and genotype calls using high-density SNP arrays
    Nucleic Acids Res, 37 (16), 5365-77
    PubMed 19581427
  25. Sørlie T (2009)
    Introducing molecular subtyping of breast cancer into the clinic?
    J Clin Oncol, 27 (8), 1153-4
    PubMed 19204193
  26. Zhou W, Muggerud AA, Vu P, Due EU, Sørlie T, Børresen-Dale AL, Wärnberg F, Langerød A (2009)
    Full sequencing of TP53 identifies identical mutations within in situ and invasive components in breast cancer suggesting clonal evolution
    Mol Oncol, 3 (3), 214-9
    PubMed 19403344

Publications 2008

  1. Alsner J, Jensen V, Kyndi M, Offersen BV, Vu P, Børresen-Dale AL, Overgaard J (2008)
    A comparison between p53 accumulation determined by immunohistochemistry and TP53 mutations as prognostic variables in tumours from breast cancer patients
    Acta Oncol, 47 (4), 600-7
    PubMed 18465328
  2. Asare N, Landvik NE, Lagadic-Gossmann D, Rissel M, Tekpli X, Ask K, Låg M, Holme JA (2008)
    1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells
    Toxicol Appl Pharmacol, 230 (2), 175-86
    PubMed 18417179
  3. Baumbusch LO, Aarøe J, Johansen FE, Hicks J, Sun H, Bruhn L, Gunderson K, Naume B, Kristensen VN, Liestøl K, Børresen-Dale AL, Lingjaerde OC (2008)
    Comparison of the Agilent, ROMA/NimbleGen and Illumina platforms for classification of copy number alterations in human breast tumors
    BMC Genomics, 9, 379
    PubMed 18691401
  4. Bergamaschi A, Kim YH, Kwei KA, La Choi Y, Bocanegra M, Langerød A, Han W, Noh DY, Huntsman DG, Jeffrey SS, Børresen-Dale AL, Pollack JR (2008)
    CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer
    Mol Oncol, 2 (4), 327-39
    PubMed 19383354
  5. Bergamaschi A, Tagliabue E, Sørlie T, Naume B, Triulzi T, Orlandi R, Russnes HG, Nesland JM, Tammi R, Auvinen P, Kosma VM, Ménard S, Børresen-Dale AL (2008)
    Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome
    J Pathol, 214 (3), 357-67
    PubMed 18044827
  6. Brosh R, Shalgi R, Liran A, Landan G, Korotayev K, Nguyen GH, Enerly E, Johnsen H, Buganim Y, Solomon H, Goldstein I, Madar S, Goldfinger N, Børresen-Dale AL, Ginsberg D, Harris CC, Pilpel Y, Oren M, Rotter V (2008)
    p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation
    Mol Syst Biol, 4, 229
    PubMed 19034270
  7. Concannon P, Haile RW, Børresen-Dale AL, Rosenstein BS, Gatti RA, Teraoka SN, Diep TA, Jansen L, Atencio DP, Langholz B, Capanu M, Liang X, Begg CB, Thomas DC, Bernstein L, Olsen JH, Malone KE, Lynch CF, Anton-Culver H, Bernstein JL, Women's Environment, Cancer, and Radiation Epidemiology Study Collaborative Group (2008)
    Variants in the ATM gene associated with a reduced risk of contralateral breast cancer
    Cancer Res, 68 (16), 6486-91
    PubMed 18701470
  8. Dumeaux V, Børresen-Dale AL, Frantzen JO, Kumle M, Kristensen VN, Lund E (2008)
    Gene expression analyses in breast cancer epidemiology: the Norwegian Women and Cancer postgenome cohort study
    Breast Cancer Res, 10 (1), R13
    PubMed 18271962
  9. Dumeaux V, Lund E, Børresen-Dale AL (2008)
    Comparison of globin RNA processing methods for genome-wide transcriptome analysis from whole blood
    Biomark Med, 2 (1), 11-21
    PubMed 20477359
  10. Gorria M, Tekpli X, Rissel M, Sergent O, Huc L, Landvik N, Fardel O, Dimanche-Boitrel MT, Holme JA, Lagadic-Gossmann D (2008)
    A new lactoferrin- and iron-dependent lysosomal death pathway is induced by benzo[a]pyrene in hepatic epithelial cells
    Toxicol Appl Pharmacol, 228 (2), 212-24
    PubMed 18255115
  11. Holm R, Kraus I, Skomedal H, Langerød A, Kristensen GB, Lyng H (2008)
    Human papillomavirus DNA and e6/e7 mRNA status in relation to survival of patients treated for cervical squamous cell carcinoma
    Open Virol J, 2, 74-81
    PubMed 19440467
  12. Horlings HM, Bergamaschi A, Nordgard SH, Kim YH, Han W, Noh DY, Salari K, Joosse SA, Reyal F, Lingjaerde OC, Kristensen VN, Børresen-Dale AL, Pollack J, van de Vijver MJ (2008)
    ESR1 gene amplification in breast cancer: a common phenomenon?
    Nat Genet, 40 (7), 807-8; author reply 810-2
    PubMed 18583965
  13. Kristensen VN, Børresen-Dale AL (2008)
    SNPs associated with molecular subtypes of breast cancer: on the usefulness of stratified Genome-wide Association Studies (GWAS) in the identification of novel susceptibility loci
    Mol Oncol, 2 (1), 12-5
    PubMed 19383324
  14. Kulle B, Frigessi A, Edvardsen H, Kristensen V, Wojnowski L (2008)
    Accounting for haplotype phase uncertainty in linkage disequilibrium estimation
    Genet Epidemiol, 32 (2), 168-78
    PubMed 17968987
  15. Lacroix J, Poët M, Huc L, Morello V, Djerbi N, Ragno M, Rissel M, Tekpli X, Gounon P, Lagadic-Gossmann D, Counillon L (2008)
    Kinetic analysis of the regulation of the Na+/H+ exchanger NHE-1 by osmotic shocks
    Biochemistry, 47 (51), 13674-85
    PubMed 19035652
  16. Mellemkjaer L, Dahl C, Olsen JH, Bertelsen L, Guldberg P, Christensen J, Børresen-Dale AL, Stovall M, Langholz B, Bernstein L, Lynch CF, Malone KE, Haile RW, Andersson M, Thomas DC, Concannon P, Capanu M, Boice JD, WECARE Study Collaborative Group, Bernstein JL (2008)
    Risk for contralateral breast cancer among carriers of the CHEK2*1100delC mutation in the WECARE Study
    Br J Cancer, 98 (4), 728-33
    PubMed 18253122
  17. Nordgard SH, Alnaes GI, Hihn B, Lingjaerde OC, Liestøl K, Tsalenko A, Sørlie T, Lønning PE, Børresen-Dale AL, Kristensen VN (2008)
    Pathway based analysis of SNPs with relevance to 5-FU therapy: relation to intratumoral mRNA expression and survival
    Int J Cancer, 123 (3), 577-85
    PubMed 18498133
  18. Nordgard SH, Johansen FE, Alnaes GI, Bucher E, Syvänen AC, Naume B, Børresen-Dale AL, Kristensen VN (2008)
    Genome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients
    Genes Chromosomes Cancer, 47 (8), 680-96
    PubMed 18398821
  19. Nourissat P, Travert M, Chevanne M, Tekpli X, Rebillard A, Le Moigne-Müller G, Rissel M, Cillard J, Dimanche-Boitrel MT, Lagadic-Gossmann D, Sergent O (2008)
    Ethanol induces oxidative stress in primary rat hepatocytes through the early involvement of lipid raft clustering
    Hepatology, 47 (1), 59-70
    PubMed 18038449
  20. Nørsett KG, Laegreid A, Kusnierczyk W, Langaas M, Ylving S, Fossmark R, Myhre S, Falkmer S, Waldum HL, Sandvik AK (2008)
    Changes in gene expression of gastric mucosa during therapeutic acid inhibition
    Eur J Gastroenterol Hepatol, 20 (7), 613-23
    PubMed 18679062
  21. Pietersen AM, Horlings HM, Hauptmann M, Langerød A, Ajouaou A, Cornelissen-Steijger P, Wessels LF, Jonkers J, van de Vijver MJ, van Lohuizen M (2008)
    EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer
    Breast Cancer Res, 10 (6), R109
    PubMed 19099573
  22. Rønneberg JA, Tost J, Solvang HK, Alnaes GI, Johansen FE, Brendeford EM, Yakhini Z, Gut IG, Lønning PE, Børresen-Dale AL, Gabrielsen OS, Kristensen VN (2008)
    GSTP1 promoter haplotypes affect DNA methylation levels and promoter activity in breast carcinomas
    Cancer Res, 68 (14), 5562-71
    PubMed 18632608
  23. Saebo S, Almoy T, Aaroe J, Aastveit AH (2008)
    ST-PLS: a multi-directional nearest shrunken centroid type classi er via PLS
    J. Chemometr., 22 (1-2), 54-62
  24. Solvang HK, Ishizuka K, Fujimoto M (2008)
    Voice activity detection based on adjustable linear prediction and GARCH models
    Speech Commun., 50 (6), 476-486
  25. Suspitsin EN, Due EU, Vu P, Hirvonen A, Børresen-Dale AL, Imyanitov EN (2008)
    TP53 mutations in synchronous and metachronous bilateral breast carcinomas
    Cancer Genet Cytogenet, 184 (2), 119-21
    PubMed 18617062
  26. Tongbai R, Idelman G, Nordgard SH, Cui W, Jacobs JL, Haggerty CM, Chanock SJ, Børresen-Dale AL, Livingston G, Shaunessy P, Chiang CH, Kristensen VN, Bilke S, Gardner K (2008)
    Transcriptional networks inferred from molecular signatures of breast cancer
    Am J Pathol, 172 (2), 495-509
    PubMed 18187569
  27. Vaclavikova R, Nordgard SH, Alnaes GI, Hubackova M, Kubala E, Kodet R, Mrhalova M, Novotny J, Gut I, Kristensen VN, Soucek P (2008)
    Single nucleotide polymorphisms in the multidrug resistance gene 1 (ABCB1): effects on its expression and clinicopathological characteristics in breast cancer patients
    Pharmacogenet Genomics, 18 (3), 263-73
    PubMed 18300948
  28. Waaseth M, Bakken K, Dumeaux V, Olsen KS, Rylander C, Figenschau Y, Lund E (2008)
    Hormone replacement therapy use and plasma levels of sex hormones in the Norwegian Women and Cancer postgenome cohort - a cross-sectional analysis
    BMC Womens Health, 8, 1
    PubMed 18194511

Publications 2007

  1. Alsner J, Rødningen OK, Overgaard J (2007)
    Differential gene expression before and after ionizing radiation of subcutaneous fibroblasts identifies breast cancer patients resistant to radiation-induced fibrosis
    Radiother Oncol, 83 (3), 261-6
    PubMed 17512072
  2. Brunsvig PF, Andersen A, Aamdal S, Kristensen V, Olsen H (2007)
    Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy
    BMC Cancer, 7, 197
    PubMed 17956601
  3. Casalini P, Iorio MV, Berno V, Bergamaschi A, Børresen Dale AL, Gasparini P, Orlandi R, Casati B, Tagliabue E, Ménard S (2007)
    Relationship between p53 and p27 expression following HER2 signaling
    Breast, 16 (6), 597-605
    PubMed 17604627
  4. Chanock SJ, Burdett L, Yeager M, Llaca V, Langerød A, Presswalla S, Kaaresen R, Strausberg RL, Gerhard DS, Kristensen V, Perou CM, Børresen-Dale AL (2007)
    Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas
    Breast Cancer Res, 9 (1), R5
    PubMed 17224074
  5. Edvardsen H, Kristensen VN, Grenaker Alnaes GI, Bøhn M, Erikstein B, Helland A, Børresen-Dale AL, Fosså SD (2007)
    Germline glutathione S-transferase variants in breast cancer: relation to diagnosis and cutaneous long-term adverse effects after two fractionation patterns of radiotherapy
    Int J Radiat Oncol Biol Phys, 67 (4), 1163-71
    PubMed 17336217
  6. Edvardsen H, Tefre T, Jansen L, Vu P, Haffty BG, Fosså SD, Kristensen VN, Børresen-Dale AL (2007)
    Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence
    Radiat Oncol, 2, 25
    PubMed 17623063
  7. Garcia-Closas M, Kristensen V, Langerød A, Qi Y, Yeager M, Burdett L, Welch R, Lissowska J, Peplonska B, Brinton L, Gerhard DS, Gram IT, Perou CM, Børresen-Dale AL, Chanock S (2007)
    Common genetic variation in TP53 and its flanking genes, WDR79 and ATP1B2, and susceptibility to breast cancer
    Int J Cancer, 121 (11), 2532-8
    PubMed 17683073
  8. Garcia-Closas M, Troester MA, Qi Y, Langerød A, Yeager M, Lissowska J, Brinton L, Welch R, Peplonska B, Gerhard DS, Gram IT, Kristensen V, Børresen-Dale AL, Chanock S, Perou CM (2007)
    Common genetic variation in GATA-binding protein 3 and differential susceptibility to breast cancer by estrogen receptor alpha tumor status
    Cancer Epidemiol Biomarkers Prev, 16 (11), 2269-75
    PubMed 18006915
  9. Holme JA, Gorria M, Arlt VM, Ovrebø S, Solhaug A, Tekpli X, Landvik NE, Huc L, Fardel O, Lagadic-Gossmann D (2007)
    Different mechanisms involved in apoptosis following exposure to benzo[a]pyrene in F258 and Hepa1c1c7 cells
    Chem Biol Interact, 167 (1), 41-55
    PubMed 17289009
  10. Huc L, Tekpli X, Holme JA, Rissel M, Solhaug A, Gardyn C, Le Moigne G, Gorria M, Dimanche-Boitrel MT, Lagadic-Gossmann D (2007)
    c-Jun NH2-terminal kinase-related Na+/H+ exchanger isoform 1 activation controls hexokinase II expression in benzo(a)pyrene-induced apoptosis
    Cancer Res, 67 (4), 1696-705
    PubMed 17308111
  11. Kapp AV, Jeffrey SS, Langerod A, Borresen-Dale AL, Han W, Noh DY, Bukholm IRK, Nicolau M, Brown PO, Tibshirani R (2007)
    Discovery and validation of breast cancer subtypes (vol 8, pg 101, 2007)
    BMC Genomics, 8, 101
  12. Kellen E, Hemelt M, Broberg K, Golka K, Kristensen VN, Hung RJ, Matullo G, Mittal RD, Porru S, Povey A, Schulz WA, Shen J, Buntinx F, Zeegers MP, Taioli E (2007)
    Pooled analysis and meta-analysis of the glutathione S-transferase P1 Ile 105Val polymorphism and bladder cancer: a HuGE-GSEC review
    Am J Epidemiol, 165 (11), 1221-30
    PubMed 17404387
  13. Kleivi K, Lind GE, Diep CB, Meling GI, Brandal LT, Nesland JM, Myklebost O, Rognum TO, Giercksky KE, Skotheim RI, Lothe RA (2007)
    Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses
    Mol Cancer, 6, 2
    PubMed 17201907
  14. Knappskog S, Chrisanthar R, Staalesen V, Børresen-Dale AL, Gram IT, Lillehaug JR, Lønning PE (2007)
    Mutations and polymorphisms of the p21B transcript in breast cancer
    Int J Cancer, 121 (4), 908-10
    PubMed 17443496
  15. Landmark H, Nahas SA, Aarøe J, Gatti R, Børresen-Dale AL, Rødningen OK (2007)
    Transcriptional response to ionizing radiation in human radiation sensitive cell lines
    Radiother Oncol, 83 (3), 256-60
    PubMed 17512073
  16. Langerød A, Zhao H, Borgan Ø, Nesland JM, Bukholm IR, Ikdahl T, Kåresen R, Børresen-Dale AL, Jeffrey SS (2007)
    TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer
    Breast Cancer Res, 9 (3), R30
    PubMed 17504517
  17. Lund E, Bakken K, Dumeaux V, Andersen V, Kumle M (2007)
    Hormone replacement therapy and breast cancer in former users of oral contraceptives--The Norwegian Women and Cancer study
    Int J Cancer, 121 (3), 645-8
    PubMed 17372914
  18. Lund E, Dumeaux V, Braaten T, Hjartåker A, Engeset D, Skeie G, Kumle M (2007)
    Cohort profile: The Norwegian Women and Cancer Study--NOWAC--Kvinner og kreft
    Int J Epidemiol, 37 (1), 36-41
    PubMed 17644530
  19. Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Strømberg M, Wiedswang G, Kvalheim G, Kåresen R, Nesland JM, Børresen-Dale AL, Sørlie T (2007)
    Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer
    Mol Oncol, 1 (2), 160-71
    PubMed 19383292
  20. Nicolau M, Tibshirani R, Børresen-Dale AL, Jeffrey SS (2007)
    Disease-specific genomic analysis: identifying the signature of pathologic biology
    Bioinformatics, 23 (8), 957-65
    PubMed 17277331
  21. Nordgard SH, Johansen FE, Alnaes GI, Naume B, Børresen-Dale AL, Kristensen VN (2007)
    Genes harbouring susceptibility SNPs are differentially expressed in the breast cancer subtypes
    Breast Cancer Res, 9 (6), 113
    PubMed 18036273
  22. Nordgard SH, Ritchie MD, Jensrud SD, Motsinger AA, Alnaes GI, Lemmon G, Berg M, Geisler S, Moore JH, Lønning PE, Børresen-Dale AL, Kristensen VN (2007)
    ABCB1 and GST polymorphisms associated with TP53 status in breast cancer
    Pharmacogenet Genomics, 17 (2), 127-36
    PubMed 17301692
  23. Petitjean A, Achatz MI, Borresen-Dale AL, Hainaut P, Olivier M (2007)
    TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes
    Oncogene, 26 (15), 2157-65
    PubMed 17401424
  24. Rebillard A, Tekpli X, Meurette O, Sergent O, LeMoigne-Muller G, Vernhet L, Gorria M, Chevanne M, Christmann M, Kaina B, Counillon L, Gulbins E, Lagadic-Gossmann D, Dimanche-Boitrel MT (2007)
    Cisplatin-induced apoptosis involves membrane fluidification via inhibition of NHE1 in human colon cancer cells
    Cancer Res, 67 (16), 7865-74
    PubMed 17699793
  25. Riise R, Ygge J, Lindman C, Stray-Pedersen A, Bek T, Rødningen OK, Heiberg A (2007)
    Ocular findings in Norwegian patients with ataxia-telangiectasia: a 5 year prospective cohort study
    Acta Ophthalmol Scand, 85 (5), 557-62
    PubMed 17376192
  26. Roca X, Olson AJ, Rao AR, Enerly E, Kristensen VN, Børresen-Dale AL, Andresen BS, Krainer AR, Sachidanandam R (2007)
    Features of 5'-splice-site efficiency derived from disease-causing mutations and comparative genomics
    Genome Res, 18 (1), 77-87
    PubMed 18032726
  27. Rødningen OK, Børresen-Dale AL, Alsner J, Hastie T, Overgaard J (2007)
    Radiation-induced gene expression in human subcutaneous fibroblasts is predictive of radiation-induced fibrosis
    Radiother Oncol, 86 (3), 314-20
    PubMed 17963910
  28. Stray-Pedersen A, Borresen-Dale AL, Paus E, Lindman CR, Burgers T, Abrahamsen TG (2007)
    Alpha fetoprotein is increasing with age in ataxia-telangiectasia
    Eur J Paediatr Neurol, 11 (6), 375-80
    PubMed 17540590
  29. Størvold GL, Gjernes E, Askautrud HA, Børresen-Dale AL, Perou CM, Frengen E (2007)
    A retroviral vector for siRNA expression in mammalian cells
    Mol Biotechnol, 35 (3), 275-82
    PubMed 17652791
  30. Suspitsin EN, Sokolenko AP, Togo AV, Lazareva YR, Turkevich EA, Matsko DE, Henrich KO, Borresen-Dale AL, Schwab M, Cornelisse CJ, Imyanitov EN (2007)
    Nonrandom distribution of oncogene amplifications in bilateral breast carcinomas: Possible role of host factors and survival bias
    Int J Cancer, 120 (2), 297-302
    PubMed 17066426
  31. Sørlie T (2007)
    Molecular classification of breast tumors: toward improved diagnostics and treatments
    Methods Mol Biol, 360, 91-114
    PubMed 17172726
  32. Wang Y, Kristensen GB, Børresen-Dale AL, Helland A (2007)
    TP53 mutations and codon 72 genotype--impact on survival among ovarian cancer patients
    Ann Oncol, 18 (5), 964-6
    PubMed 17488735
  33. Yosef N, Yakhini Z, Tsalenko A, Kristensen V, Børresen-Dale AL, Ruppin E, Sharan R (2007)
    A supervised approach for identifying discriminating genotype patterns and its application to breast cancer data
    Bioinformatics, 23 (2), e91-8
    PubMed 17237111

Publications 2006

  1. Anensen N, Skavland J, Stapnes C, Ryningen A, Børresen-Dale AL, Gjertsen BT, Bruserud Ø (2006)
    Acute myelogenous leukemia in a patient with Li-Fraumeni syndrome treated with valproic acid, theophyllamine and all-trans retinoic acid: a case report
    Leukemia, 20 (4), 734-6
    PubMed 16437140
  2. Baumbusch LO, Myhre S, Langerød A, Bergamaschi A, Geisler SB, Lønning PE, Deppert W, Dornreiter I, Børresen-Dale AL (2006)
    Expression of full-length p53 and its isoform Deltap53 in breast carcinomas in relation to mutation status and clinical parameters
    Mol Cancer, 5, 47
    PubMed 17054774
  3. Bergamaschi A, Kim YH, Wang P, Sørlie T, Hernandez-Boussard T, Lonning PE, Tibshirani R, Børresen-Dale AL, Pollack JR (2006)
    Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer
    Genes Chromosomes Cancer, 45 (11), 1033-40
    PubMed 16897746
  4. Chi JT, Wang Z, Nuyten DS, Rodriguez EH, Schaner ME, Salim A, Wang Y, Kristensen GB, Helland A, Børresen-Dale AL, Giaccia A, Longaker MT, Hastie T, Yang GP, van de Vijver MJ, Brown PO (2006)
    Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers
    PLoS Med, 3 (3), e47
    PubMed 16417408
  5. Diep CB, Kleivi K, Ribeiro FR, Teixeira MR, Lindgjaerde OC, Lothe RA (2006)
    The order of genetic events associated with colorectal cancer progression inferred from meta-analysis of copy number changes
    Genes Chromosomes Cancer, 45 (1), 31-41
    PubMed 16145679
  6. Drageset V, Nesland JM, Erikstein B, Skovlund E, Sommer H, Anker G, Wist E, Lundgren S, Bergh J, Kvalheim G (2006)
    Monitoring of disseminated tumor cells in bone marrow in high-risk breast cancer patients treated with high-dose chemotherapy
    Int J Cancer, 118 (11), 2877-81
    PubMed 16381016
  7. Dumeaux V, Johansen J, Børresen-Dale AL, Lund E (2006)
    Gene expression profiling of whole-blood samples from women exposed to hormone replacement therapy
    Mol Cancer Ther, 5 (4), 868-76
    PubMed 16648556
  8. Edvardsen H, Irene Grenaker Alnaes G, Tsalenko A, Mulcahy T, Yuryev A, Lindersson M, Lien S, Omholt S, Syvänen AC, Børresen-Dale AL, Kristensen VN (2006)
    Experimental validation of data mined single nucleotide polymorphisms from several databases and consecutive dbSNP builds
    Pharmacogenet Genomics, 16 (3), 207-17
    PubMed 16495780
  9. Gorria M, Tekpli X, Sergent O, Huc L, Gaboriau F, Rissel M, Chevanne M, Dimanche-Boitrel MT, Lagadic-Gossmann D (2006)
    Membrane fluidity changes are associated with benzo[a]pyrene-induced apoptosis in F258 cells: protection by exogenous cholesterol
    Ann N Y Acad Sci, 1090, 108-12
    PubMed 17384252
  10. Heikkinen K, Rapakko K, Karppinen SM, Erkko H, Knuutila S, Lundán T, Mannermaa A, Børresen-Dale AL, Borg A, Barkardottir RB, Petrini J, Winqvist R (2006)
    RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability
    Carcinogenesis, 27 (8), 1593-9
    PubMed 16474176
  11. Helland A, Johnsen H, Frøyland C, Landmark HB, Saetersdal AB, Holmen MM, Gjertsen T, Nesland JM, Ottestad W, Jeffrey SS, Ottestad LO, Rodningen OK, Sherlock G, Børresen-Dale AL (2006)
    Radiation-induced effects on gene expression: an in vivo study on breast cancer
    Radiother Oncol, 80 (2), 230-5
    PubMed 16890317
  12. Hicks J, Krasnitz A, Lakshmi B, Navin NE, Riggs M, Leibu E, Esposito D, Alexander J, Troge J, Grubor V, Yoon S, Wigler M, Ye K, Børresen-Dale AL, Naume B, Schlicting E, Norton L, Hägerström T, Skoog L, Auer G, Månér S, Lundin P, Zetterberg A (2006)
    Novel patterns of genome rearrangement and their association with survival in breast cancer
    Genome Res, 16 (12), 1465-79
    PubMed 17142309
  13. Huc L, Rissel M, Solhaug A, Tekpli X, Gorria M, Torriglia A, Holme JA, Dimanche-Boitrel MT, Lagadic-Gossmann D (2006)
    Multiple apoptotic pathways induced by p53-dependent acidification in benzo[a]pyrene-exposed hepatic F258 cells
    J Cell Physiol, 208 (3), 527-37
    PubMed 16688778
  14. Irish JM, Anensen N, Hovland R, Skavland J, Børresen-Dale AL, Bruserud O, Nolan GP, Gjertsen BT (2006)
    Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53
    Blood, 109 (6), 2589-96
    PubMed 17105820
  15. Kapp AV, Jeffrey SS, Langerød A, Børresen-Dale AL, Han W, Noh DY, Bukholm IR, Nicolau M, Brown PO, Tibshirani R (2006)
    Discovery and validation of breast cancer subtypes
    BMC Genomics, 7, 231
    PubMed 16965636
  16. Kleivi K (2006)
    Advances in the genetics and epigenetics of gene regulation and human disease
    Genome Biol, 7 (8), 325
    PubMed 16934107
  17. Kristensen VN, Edvardsen H, Tsalenko A, Nordgard SH, Sørlie T, Sharan R, Vailaya A, Ben-Dor A, Lønning PE, Lien S, Omholt S, Syvänen AC, Yakhini Z, Børresen-Dale AL (2006)
    Genetic variation in putative regulatory loci controlling gene expression in breast cancer
    Proc Natl Acad Sci U S A, 103 (20), 7735-40
    PubMed 16684880
  18. Kristensen VN, Tsalenko A, Geisler J, Faldaas A, Grenaker GI, Lingjaerde OC, Fjeldstad S, Yakhini Z, Lønning PE, Børresen-Dale AL (2006)
    Multilocus analysis of SNP and metabolic data within a given pathway
    BMC Genomics, 7, 5
    PubMed 16412218
  19. Lahermo P, Liljedahl U, Alnaes G, Axelsson T, Brookes AJ, Ellonen P, Groop PH, Halldén C, Holmberg D, Holmberg K, Keinänen M, Kepp K, Kere J, Kiviluoma P, Kristensen V, Lindgren C, Odeberg J, Osterman P, Parkkonen M, Saarela J, Sterner M, Strömqvist L, Talas U, Wessman M, Palotie A et al. (2006)
    A quality assessment survey of SNP genotyping laboratories
    Hum Mutat, 27 (7), 711-4
    PubMed 16786507
  20. Langholz B, Bernstein JL, Bernstein L, Olsen JH, Børresen-Dale AL, Rosenstein BS, Gatti RA, WECARE Study Collaborative Group, Concannon P (2006)
    On the proposed association of the ATM variants 5557G>A and IVS38-8T>C and bilateral breast cancer
    Int J Cancer, 119 (3), 724-5
    PubMed 16496408
  21. Lind GE, Kleivi K, Meling GI, Teixeira MR, Thiis-Evensen E, Rognum TO, Lothe RA (2006)
    ADAMTS1, CRABP1, and NR3C1 identified as epigenetically deregulated genes in colorectal tumorigenesis
    Cell Oncol, 28 (5-6), 259-72
    PubMed 17167179
  22. Lønning PE, Børresen-Dale AL (2006)
    Interaction between p53 staining and high-dose chemotherapy in breast cancer
    Clin Cancer Res, 12 (7 Pt 1), 2289
    PubMed 16609046
  23. Muggerud AA, Johnsen H, Barnes DA, Steel A, Lønning PE, Naume B, Sørlie T, Børresen-Dale AL (2006)
    Evaluation of MetriGenix custom 4D arrays applied for detection of breast cancer subtypes
    BMC Cancer, 6, 59
    PubMed 16536878
  24. Olivier M, Langerød A, Carrieri P, Bergh J, Klaar S, Eyfjord J, Theillet C, Rodriguez C, Lidereau R, Bièche I, Varley J, Bignon Y, Uhrhammer N, Winqvist R, Jukkola-Vuorinen A, Niederacher D, Kato S, Ishioka C, Hainaut P, Børresen-Dale AL (2006)
    The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer
    Clin Cancer Res, 12 (4), 1157-67
    PubMed 16489069
  25. Paracchini V, Raimondi S, Gram IT, Kang D, Kocabas NA, Kristensen VN, Li D, Parl FF, Rylander-Rudqvist T, Soucek P, Zheng W, Wedren S, Taioli E (2006)
    Meta- and pooled analyses of the cytochrome P-450 1B1 Val432Leu polymorphism and breast cancer: a HuGE-GSEC review
    Am J Epidemiol, 165 (2), 115-25
    PubMed 17053044
  26. Ribeiro FR, Henrique R, Hektoen M, Berg M, Jerónimo C, Teixeira MR, Lothe RA (2006)
    Comparison of chromosomal and array-based comparative genomic hybridization for the detection of genomic imbalances in primary prostate carcinomas
    Mol Cancer, 5, 33
    PubMed 16952311
  27. Staalesen V, Knappskog S, Chrisanthar R, Nordgard SH, Løkkevik E, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Gram IT, Kristensen VN, Børresen-Dale AL, Lillehaug JR, Lønning PE (2006)
    The novel p21 polymorphism p21G251A is associated with locally advanced breast cancer
    Clin Cancer Res, 12 (20 Pt 1), 6000-4
    PubMed 17062672
  28. Sørlie T, Perou CM, Fan C, Geisler S, Aas T, Nobel A, Anker G, Akslen LA, Botstein D, Børresen-Dale AL, Lønning PE (2006)
    Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer
    Mol Cancer Ther, 5 (11), 2914-8
    PubMed 17121939
  29. Sørlie T, Wang Y, Xiao C, Johnsen H, Naume B, Samaha RR, Børresen-Dale AL (2006)
    Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms
    BMC Genomics, 7, 127
    PubMed 16729877
  30. Tavtigian SV, Pierotti MA, Børresen-Dale AL (2006)
    International Agency for Research on Cancer workshop on 'Expression array analyses in breast cancer taxonomy'
    Breast Cancer Res, 8 (6), 303
    PubMed 17096863
  31. Tommiska J, Jansen L, Kilpivaara O, Edvardsen H, Kristensen V, Tamminen A, Aittomäki K, Blomqvist C, Børresen-Dale AL, Nevanlinna H (2006)
    ATM variants and cancer risk in breast cancer patients from Southern Finland
    BMC Cancer, 6, 209
    PubMed 16914028
  32. Tsalenko A, Sharan R, Kristensen V, Edvardsen H, Børresen-Dale AL, Ben-Dor A, Yakhini Z (2006)
    Analysis of SNP-expression association matrices
    J Bioinform Comput Biol, 4 (2), 259-74
    PubMed 16819783
  33. Wang Y, Kringen P, Kristensen GB, Holm R, Baekelandt MMO, Olivier M, Skomedal H, Hainaut P, Trope CG, Abeler VM, Nesland JM, Borresen-Dale AL, Helland A (2006)
    Effect of the codon 72 polymorphism (c.215G > C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma (vol 24, pg 21, 2004)
    Hum. Mutat., 27 (2), 209-210

Publications 2005

  1. Benetkiewicz M, Wang Y, Schaner M, Wang P, Mantripragada KK, Buckley PG, Kristensen G, Børresen-Dale AL, Dumanski JP (2005)
    High-resolution gene copy number and expression profiling of human chromosome 22 in ovarian carcinomas
    Genes Chromosomes Cancer, 42 (3), 228-37
    PubMed 15578687
  2. Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sørlie T, Dai H, He YD, van't Veer LJ, Bartelink H, van de Rijn M, Brown PO, van de Vijver MJ (2005)
    Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
    Proc Natl Acad Sci U S A, 102 (10), 3738-43
    PubMed 15701700
  3. Come SE, Buzdar AU, Ingle JN, Arteaga CL, Brodie AM, Colditz GA, Johnston SR, Kristensen VN, Lønning PE, McDonnell DP, Osborne CK, Russo J, Santen RJ, Yee D, Hart CS (2005)
    Proceedings of the Fourth International Conference on Recent Advances and Future Directions in Endocrine Manipulation of Breast Cancer: conference summary statement
    Clin Cancer Res, 11 (2 Pt 2), 861s-4s
    PubMed 15701878
  4. Kleivi K, Diep CB, Pandis N, Heim S, Teixeira MR, Lothe RA (2005)
    TP53 mutations are associated with a particular pattern of genomic imbalances in breast carcinomas
    J Pathol, 207 (1), 14-9
    PubMed 16007576
  5. Kringen P, Bergamaschi A, Due EU, Wang Y, Tagliabue E, Nesland JM, Nehman A, Tönisson N, Børresen-Dale AL (2005)
    Evaluation of arrayed primer extension for TP53 mutation detection in breast and ovarian carcinomas
    Biotechniques, 39 (5), 755-61
    PubMed 16312222
  6. Kringen P, Wang Y, Dumeaux V, Nesland JM, Kristensen G, Borresen-Dale AL, Dorum A (2005)
    TP53 mutations in ovarian carcinomas from sporadic cases and carriers of two distinct BRCA1 founder mutations; relation to age at diagnosis and survival
    BMC Cancer, 5, 134
    PubMed 16229746
  7. Kristensen VN, Sørlie T, Geisler J, Langerød A, Yoshimura N, Kåresen R, Harada N, Lønning PE, Børresen-Dale AL (2005)
    Gene expression profiling of breast cancer in relation to estrogen receptor status and estrogen-metabolizing enzymes: clinical implications
    Clin Cancer Res, 11 (2 Pt 2), 878s-83s
    PubMed 15701881
  8. Kristensen VN, Sørlie T, Geisler J, Yoshimura N, Linegjaerde OC, Glad I, Frigessi A, Harada N, Lønning PE, Børresen-Dale AL (2005)
    Effects of anastrozole on the intratumoral gene expression in locally advanced breast cancer
    J Steroid Biochem Mol Biol, 95 (1-5), 105-11
    PubMed 16023338
  9. Lønning PE, Sørlie T, Børresen-Dale AL (2005)
    Genomics in breast cancer-therapeutic implications
    Nat Clin Pract Oncol, 2 (1), 26-33
    PubMed 16264853
  10. Maguire P, Margolin S, Skoglund J, Sun XF, Gustafsson JA, Børresen-Dale AL, Lindblom A (2005)
    Estrogen receptor beta (ESR2) polymorphisms in familial and sporadic breast cancer
    Breast Cancer Res Treat, 94 (2), 145-52
    PubMed 16261413
  11. Olsen JH, Hahnemann JM, Børresen-Dale AL, Tretli S, Kleinerman R, Sankila R, Hammarström L, Robsahm TE, Kääriäinen H, Bregård A, Brøndum-Nielsen K, Yuen J, Tucker M (2005)
    Breast and other cancers in 1445 blood relatives of 75 Nordic patients with ataxia telangiectasia
    Br J Cancer, 93 (2), 260-5
    PubMed 15942625
  12. Rødningen OK, Overgaard J, Alsner J, Hastie T, Børresen-Dale AL (2005)
    Microarray analysis of the transcriptional response to single or multiple doses of ionizing radiation in human subcutaneous fibroblasts
    Radiother Oncol, 77 (3), 231-40
    PubMed 16297999
  13. Schaner ME, Davidson B, Skrede M, Reich R, Flørenes VA, Risberg B, Berner A, Goldberg I, Givant-Horwitz V, Tropè CG, Kristensen GB, Nesland JM, Børresen-Dale AL (2005)
    Variation in gene expression patterns in effusions and primary tumors from serous ovarian cancer patients
    Mol Cancer, 4, 26
    PubMed 16042759
  14. Sharma P, Sahni NS, Tibshirani R, Skaane P, Urdal P, Berghagen H, Jensen M, Kristiansen L, Moen C, Sharma P, Zaka A, Arnes J, Sauer T, Akslen LA, Schlichting E, Børresen-Dale AL, Lönneborg A (2005)
    Early detection of breast cancer based on gene-expression patterns in peripheral blood cells
    Breast Cancer Res, 7 (5), R634-44
    PubMed 16168108
  15. Sørlie T, Johnsen H, Vu P, Lind GE, Lothe R, Børresen-Dale AL (2005)
    Mutation screening of the TP53 gene by temporal temperature gradient gel electrophoresis
    Methods Mol Biol, 291, 207-16
    PubMed 15502225
  16. Tsalenko A, Sharan R, Edvardsen H, Kristensen V, Børresen-Dale AL, Ben-Dor A, Yakhini Z (2005)
    Analysis of SNP-expression association matrices
    Proc IEEE Comput Syst Bioinform Conf, 135-43
    PubMed 16447971
  17. Wang Y, Helland A, Holm R, Kristensen GB, Børresen-Dale AL (2005)
    PIK3CA mutations in advanced ovarian carcinomas
    Hum Mutat, 25 (3), 322
    PubMed 15712344
  18. Wang Y, Kristensen GB, Helland A, Nesland JM, Børresen-Dale AL, Holm R (2005)
    Protein expression and prognostic value of genes in the erb-b signaling pathway in advanced ovarian carcinomas
    Am J Clin Pathol, 124 (3), 392-401
    PubMed 16191507
  19. Wolf M, Edgren H, Muggerud A, Kilpinen S, Huusko P, Sørlie T, Mousses S, Kallioniemi O (2005)
    NMD microarray analysis for rapid genome-wide screen of mutated genes in cancer
    Cell Oncol, 27 (3), 169-73
    PubMed 16037637
  20. Aas T, Geisler S, Helle H, Børresen-Dale AL, Lønning PE, Akslen LA (2005)
    Prognostic and predictive value of changes in tumour cell proliferation in locally advanced breast cancer primarily treated with doxorubicin
    Oncol Rep, 13 (3), 525-30
    PubMed 15706428

Publications 2004

  1. Bernstein JL, Langholz B, Haile RW, Bernstein L, Thomas DC, Stovall M, Malone KE, Lynch CF, Olsen JH, Anton-Culver H, Shore RE, Boice JD, Berkowitz GS, Gatti RA, Teitelbaum SL, Smith SA, Rosenstein BS, Børresen-Dale AL, Concannon P, Thompson WD, WECARE study (2004)
    Study design: evaluating gene-environment interactions in the etiology of breast cancer - the WECARE study
    Breast Cancer Res, 6 (3), R199-214
    PubMed 15084244
  2. Kleivi K, Teixeira MR, Eknaes M, Diep CB, Jakobsen KS, Hamelin R, Lothe RA (2004)
    Genome signatures of colon carcinoma cell lines
    Cancer Genet Cytogenet, 155 (2), 119-31
    PubMed 15571797
  3. Lingjaerde OC, Baumbusch LO, Liestøl K, Glad IK, Børresen-Dale AL (2004)
    CGH-Explorer: a program for analysis of array-CGH data
    Bioinformatics, 21 (6), 821-2
    PubMed 15531610
  4. Smits KM, Benhamou S, Garte S, Weijenberg MP, Alamanos Y, Ambrosone C, Autrup H, Autrup JL, Baranova H, Bathum L, Boffetta P, Bouchardy C, Brockmoller J, Butkiewicz D, Cascorbi I, Clapper ML, Coutelle C, Daly AK, Muzi G, Dolzan V, Duzhak TG, Farker K, Golka K, Haugen A, Hein DW et al. (2004)
    Association of metabolic gene polymorphisms with tobacco consumption in healthy controls
    Int J Cancer, 110 (2), 266-70
    PubMed 15069692
  5. Soucek P, Skjelbred CF, Svendsen M, Kristensen T, Kure EH, Kristensen VN (2004)
    Single-track sequencing for genotyping of multiple SNPs in the N-acetyltransferase 1 (NAT1) gene
    BMC Biotechnol, 4, 28
    PubMed 15563733
  6. Stray-Pedersen A, Jónsson T, Heiberg A, Lindman CR, Widing E, Aaberge IS, Borresen-Dale AL, Abrahamsen TG (2004)
    The impact of an early truncating founder ATM mutation on immunoglobulins, specific antibodies and lymphocyte populations in ataxia-telangiectasia patients and their parents
    Clin Exp Immunol, 137 (1), 179-86
    PubMed 15196260
  7. Staalesen V, Falck J, Geisler S, Bartkova J, Børresen-Dale AL, Lukas J, Lillehaug JR, Bartek J, Lønning PE (2004)
    Alternative splicing and mutation status of CHEK2 in stage III breast cancer
    Oncogene, 23 (52), 8535-44
    PubMed 15361853
  8. Sørlie T (2004)
    Molecular portraits of breast cancer: tumour subtypes as distinct disease entities
    Eur J Cancer, 40 (18), 2667-75
    PubMed 15571950
  9. Troester MA, Hoadley KA, Sørlie T, Herbert BS, Børresen-Dale AL, Lønning PE, Shay JW, Kaufmann WK, Perou CM (2004)
    Cell-type-specific responses to chemotherapeutics in breast cancer
    Cancer Res, 64 (12), 4218-26
    PubMed 15205334
  10. Usary J, Llaca V, Karaca G, Presswala S, Karaca M, He X, Langerød A, Kåresen R, Oh DS, Dressler LG, Lønning PE, Strausberg RL, Chanock S, Børresen-Dale AL, Perou CM (2004)
    Mutation of GATA3 in human breast tumors
    Oncogene, 23 (46), 7669-78
    PubMed 15361840
  11. Wang Y, Helland A, Holm R, Skomedal H, Abeler VM, Danielsen HE, Tropé CG, Børresen-Dale AL, Kristensen GB (2004)
    TP53 mutations in early-stage ovarian carcinoma, relation to long-term survival
    Br J Cancer, 90 (3), 678-85
    PubMed 14760384
  12. Wang Y, Kringen P, Kristensen GB, Holm R, Baekelandt MM, Olivier M, Skomedal H, Hainaut P, Tropé CG, Abeler VM, Nesland JM, Børresen-Dale AL, Helland A (2004)
    Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma
    Hum Mutat, 24 (1), 21-34
    PubMed 15221786
  13. Zhao H, Langerød A, Ji Y, Nowels KW, Nesland JM, Tibshirani R, Bukholm IK, Kåresen R, Botstein D, Børresen-Dale AL, Jeffrey SS (2004)
    Different gene expression patterns in invasive lobular and ductal carcinomas of the breast
    Mol Biol Cell, 15 (6), 2523-36
    PubMed 15034139
  14. Zimarina TC, Kristensen VN, Imianitov EN, Bershteĭn LM (2004)
    [Polymorphisms of CYP1B1 and COMT in breast and endometrial cancer]
    Mol Biol (Mosk), 38 (3), 386-93
    PubMed 15285606

Publications 2003

  1. Bernstein JL, Bernstein L, Thompson WD, Lynch CF, Malone KE, Teitelbaum SL, Olsen JH, Anton-Culver H, Boice JD, Rosenstein BS, Børresen-Dale AL, Gatti RA, Concannon P, Haile RW, WECARE Study Collaborative Group (2003)
    ATM variants 7271T>G and IVS10-6T>G among women with unilateral and bilateral breast cancer
    Br J Cancer, 89 (8), 1513-6
    PubMed 14562025
  2. Bernstein JL, Teraoka S, Haile RW, Børresen-Dale AL, Rosenstein BS, Gatti RA, Diep AT, Jansen L, Atencio DP, Olsen JH, Bernstein L, Teitelbaum SL, Thompson WD, Concannon P, WECARE Study Collaborative Group (2003)
    Designing and implementing quality control for multi-center screening of mutations in the ATM gene among women with breast cancer
    Hum Mutat, 21 (5), 542-50
    PubMed 12673797
  3. Bukholm IR, Husdal A, Nesland JM, Langerød A, Bukholm G (2003)
    Overexpression of cyclin A overrides the effect of p53 alterations in breast cancer patients with long follow-up time
    Breast Cancer Res Treat, 80 (2), 199-206
    PubMed 12908823
  4. Børresen-Dale AL (2003)
    TP53 and breast cancer
    Hum Mutat, 21 (3), 292-300
    PubMed 12619115
  5. Børresen-Dale AL (2003)
    Genetic profiling of breast cancer: from molecular portraits to clinical utility
    Int J Biol Markers, 18 (1), 54-6
    PubMed 12699064
  6. Geisler S, Børresen-Dale AL, Johnsen H, Aas T, Geisler J, Akslen LA, Anker G, Lønning PE (2003)
    TP53 gene mutations predict the response to neoadjuvant treatment with 5-fluorouracil and mitomycin in locally advanced breast cancer
    Clin Cancer Res, 9 (15), 5582-8
    PubMed 14654539
  7. Haslekås C, Grini PE, Nordgard SH, Thorstensen T, Viken MK, Nygaard V, Aalen RB (2003)
    ABI3 mediates expression of the peroxiredoxin antioxidant AtPER1 gene and induction by oxidative stress
    Plant Mol Biol, 53 (3), 313-26
    PubMed 14750521
  8. Haslekås C, Viken MK, Grini PE, Nygaard V, Nordgard SH, Meza TJ, Aalen RB (2003)
    Seed 1-cysteine peroxiredoxin antioxidants are not involved in dormancy, but contribute to inhibition of germination during stress
    Plant Physiol, 133 (3), 1148-57
    PubMed 14526116
  9. Kristiansen M, Helland A, Kristensen GB, Olsen AO, Lønning PE, Børresen-Dale AL, Ørstavik KH (2003)
    X chromosome inactivation in cervical cancer patients
    Cancer Genet Cytogenet, 146 (1), 73-6
    PubMed 14499700
  10. Langerød A, Strømberg M, Chin K, Kristensen VN, Børresen-Dale AL (2003)
    BUB1 infrequently mutated in human breast carcinomas
    Hum Mutat, 22 (5), 420
    PubMed 14517964
  11. Pan-Hammarström Q, Dai S, Zhao Y, van Dijk-Härd IF, Gatti RA, Børresen-Dale AL, Hammarström L (2003)
    ATM is not required in somatic hypermutation of VH, but is involved in the introduction of mutations in the switch mu region
    J Immunol, 170 (7), 3707-16
    PubMed 12646636
  12. Schaner ME, Ross DT, Ciaravino G, Sorlie T, Troyanskaya O, Diehn M, Wang YC, Duran GE, Sikic TL, Caldeira S, Skomedal H, Tu IP, Hernandez-Boussard T, Johnson SW, O'Dwyer PJ, Fero MJ, Kristensen GB, Borresen-Dale AL, Hastie T, Tibshirani R, van de Rijn M, Teng NN, Longacre TA, Botstein D, Brown PO et al. (2003)
    Gene expression patterns in ovarian carcinomas
    Mol Biol Cell, 14 (11), 4376-86
    PubMed 12960427
  13. Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, Demeter J, Perou CM, Lønning PE, Brown PO, Børresen-Dale AL, Botstein D (2003)
    Repeated observation of breast tumor subtypes in independent gene expression data sets
    Proc Natl Acad Sci U S A, 100 (14), 8418-23
    PubMed 12829800
  14. Soucek P, Gut I, Trneny M, Skovlund E, Grenaker Alnaes G, Kristensen T, Børresen-Dale AL, Kristensen VN (2003)
    Multiplex single-tube screening for mutations in the Nijmegen Breakage Syndrome (NBS1) gene in Hodgkin's and non-Hodgkin's lymphoma patients of Slavic origin
    Eur J Hum Genet, 11 (5), 416-9
    PubMed 12734548
  15. Stacy JE, Kausmally L, Simonsen B, Nordgard SH, Alsøe L, Michaelsen TE, Brekke OH (2003)
    Direct isolation of recombinant human antibodies against group B Neisseria meningitidis from scFv expression libraries
    J Immunol Methods, 283 (1-2), 247-59
    PubMed 14659916
  16. Yoshimura N, Harada N, Bukholm I, Kåresen R, Børresen-Dale AL, Kristensen VN (2003)
    Intratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancer
    Breast Cancer Res, 6 (2), R46-55
    PubMed 14979917
  17. Aas T, Geisler S, Eide GE, Haugen DF, Varhaug JE, Bassøe AM, Thorsen T, Berntsen H, Børresen-Dale AL, Akslen LA, Lønning PE (2003)
    Predictive value of tumour cell proliferation in locally advanced breast cancer treated with neoadjuvant chemotherapy
    Eur J Cancer, 39 (4), 438-46
    PubMed 12751373

Publications 2002

  1. Allinen M, Launonen V, Laake K, Jansen L, Huusko P, Kääriäinen H, Børresen-Dale AL, Winqvist R (2002)
    ATM mutations in Finnish breast cancer patients
    J Med Genet, 39 (3), 192-6
    PubMed 11897822
  2. Bernstein JL, Seminara D, Børresen-Dale AL (2002)
    Workshop on The Epidemiology of the ATM Gene: Impact on Breast Cancer Risk and Treatment, Present Status and Future Focus, Lillehammer, Norway, 29 June 2002
    Breast Cancer Res, 4 (6), 249-52
    PubMed 12473172
  3. Børresen AL (2002)
    Mismatch detection using heteroduplex analysis
    Curr Protoc Hum Genet, Chapter 7, Unit 7.3
    PubMed 18428333
  4. Jeffrey SS, Fero MJ, Børresen-Dale AL, Botstein D (2002)
    Expression array technology in the diagnosis and treatment of breast cancer
    Mol Interv, 2 (2), 101-9
    PubMed 14993355
  5. Kleivi K, Lothe RA, Heim S, Tsarouha H, Kraggerud SM, Pandis N, Papadopoulou A, Andersen J, Jakobsen KS, Teixeira MR (2002)
    Genome profiling of breast cancer cells selected against in vitro shows copy number changes
    Genes Chromosomes Cancer, 33 (3), 304-9
    PubMed 11807988
  6. Kringen P, Egedal S, Pedersen JC, Harbitz TB, Tveit KM, Berg K, Børresen-Dale AL, Andersen TI (2002)
    BRCA1 mutation screening using restriction endonuclease fingerprinting-single-strand conformation polymorphism in an automated capillary electrophoresis system
    Electrophoresis, 23 (24), 4085-91
    PubMed 12481264
  7. Kristiansen M, Langerød A, Knudsen GP, Weber BL, Børresen-Dale AL, Orstavik KH (2002)
    High frequency of skewed X inactivation in young breast cancer patients
    J Med Genet, 39 (1), 30-3
    PubMed 11826021
  8. Langerød A, Bukholm IR, Bregård A, Lønning PE, Andersen TI, Rognum TO, Meling GI, Lothe RA, Børresen-Dale AL (2002)
    The TP53 codon 72 polymorphism may affect the function of TP53 mutations in breast carcinomas but not in colorectal carcinomas
    Cancer Epidemiol Biomarkers Prev, 11 (12), 1684-8
    PubMed 12496062
  9. Passarino G, Cavalleri GL, Lin AA, Cavalli-Sforza LL, Børresen-Dale AL, Underhill PA (2002)
    Different genetic components in the Norwegian population revealed by the analysis of mtDNA and Y chromosome polymorphisms
    Eur J Hum Genet, 10 (9), 521-9
    PubMed 12173029
  10. Pollack JR, Sørlie T, Perou CM, Rees CA, Jeffrey SS, Lonning PE, Tibshirani R, Botstein D, Børresen-Dale AL, Brown PO (2002)
    Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors
    Proc Natl Acad Sci U S A, 99 (20), 12963-8
    PubMed 12297621
  11. Soucek P, Sarmanová J, Kristensen VN, Apltauerová M, Gut I (2002)
    Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas
    Int Arch Occup Environ Health, 75 Suppl, S86-92
    PubMed 12397416
  12. Zhao H, Hastie T, Whitfield ML, Børresen-Dale AL, Jeffrey SS (2002)
    Optimization and evaluation of T7 based RNA linear amplification protocols for cDNA microarray analysis
    BMC Genomics, 3 (1), 31
    PubMed 12445333

Publications 2001

  1. Bjørheim J, Ekstrøm PO, Fossberg E, Børresen-Dale AL, Gaudernack G (2001)
    Automated constant denaturant capillary electrophoresis applied for detection of KRAS exon 1 mutations
    Biotechniques, 30 (5), 972-5
    PubMed 11355359
  2. Børresen-Dale AL, Hovig E, Smith-Sørensen B (2001)
    Detection of mutations by denaturing gradient gel electrophoresis
    Curr Protoc Hum Genet, Chapter 7, Unit 7.5
    PubMed 18428306
  3. Dai H, Holm R, Kristensen GB, Abeler VM, Børresen-Dale AL, Helland A (2001)
    Fibroblast growth factor receptor 3 (FGFR3) - analyses of the S249C mutation and protein expression in primary cervical carcinomas
    Anal Cell Pathol, 23 (2), 45-9
    PubMed 11904459
  4. Forus A, Sørlie T, Børresen-Dale AL, Myklebost O (2001)
    [Microarray technology--potential in cancer research]
    Tidsskr Nor Laegeforen, 121 (21), 2498-503
    PubMed 11875927
  5. Geisler S, Lønning PE, Aas T, Johnsen H, Fluge O, Haugen DF, Lillehaug JR, Akslen LA, Børresen-Dale AL (2001)
    Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer
    Cancer Res, 61 (6), 2505-12
    PubMed 11289122
  6. Jain AN, Chin K, Børresen-Dale AL, Erikstein BK, Eynstein Lonning P, Kaaresen R, Gray JW (2001)
    Quantitative analysis of chromosomal CGH in human breast tumors associates copy number abnormalities with p53 status and patient survival
    Proc Natl Acad Sci U S A, 98 (14), 7952-7
    PubMed 11438741
  7. Kristensen VN, Børresen-Dale AL, Kristensen T (2001)
    Hypervariable area in the 5' flanking region of GSTP1, previously reported as a minisatellite ATAAA repeat
    Hum Mutat, 17 (3), 238-9
    PubMed 11241854
  8. Kristensen VN, Harada N, Kristensen T, Borresen-Dale AL (2001)
    [Genetic polymorphism and variability of steroid hormone metabolism: connection with risk of developing breast neoplasms]
    Vopr Onkol, 47 (2), 156-9
    PubMed 11383450
  9. Kristensen VN, Kelefiotis D, Kristensen T, Børresen-Dale AL (2001)
    High-throughput methods for detection of genetic variation
    Biotechniques, 30 (2), 318-22, 324, 326 passim
    PubMed 11233601
  10. Kristensen VN, Kure EH, Erikstein B, Harada N, Børresen-Dale A (2001)
    Genetic susceptibility and environmental estrogen-like compounds
    Mutat Res, 482 (1-2), 77-82
    PubMed 11535251
  11. Lønning PE, Sørlie T, Perou CM, Brown PO, Botstein D, Børresen-Dale AL (2001)
    Microarrays in primary breast cancer--lessons from chemotherapy studies
    Endocr Relat Cancer, 8 (3), 259-63
    PubMed 11566617
  12. Olsen JH, Hahnemann JM, Børresen-Dale AL, Brøndum-Nielsen K, Hammarström L, Kleinerman R, Kääriäinen H, Lönnqvist T, Sankila R, Seersholm N, Tretli S, Yuen J, Boice JD, Tucker M (2001)
    Cancer in patients with ataxia-telangiectasia and in their relatives in the nordic countries
    J Natl Cancer Inst, 93 (2), 121-7
    PubMed 11208881
  13. Salahshor S, Haixin L, Huo H, Kristensen VN, Loman N, Sjöberg-Margolin S, Borg A, Børresen-Dale AL, Vorechovsky I, Lindblom A (2001)
    Low frequency of E-cadherin alterations in familial breast cancer
    Breast Cancer Res, 3 (3), 199-207
    PubMed 11305955
  14. Sandvik AK, Støren O, Nørsett K, Laegreid A, Børresen-Dale AL, Myklebost O (2001)
    [Measurement of gene activity by DNA microarrays]
    Tidsskr Nor Laegeforen, 121 (10), 1225-8
    PubMed 11402749
  15. Sørlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, Hastie T, Eisen MB, van de Rijn M, Jeffrey SS, Thorsen T, Quist H, Matese JC, Brown PO, Botstein D, Lønning PE, Børresen-Dale AL (2001)
    Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    Proc Natl Acad Sci U S A, 98 (19), 10869-74
    PubMed 11553815
  16. Warren W, Hovig E, Smith-Sørensen B, Børresen AL, Fujimura FK, Liu Q, Feng J, Sommer SS (2001)
    Detection of mutations by single-strand conformation polymorphism (SSCP) analysis and SSCP-hybrid methods
    Curr Protoc Hum Genet, Chapter 7, Unit 7.4
    PubMed 18428305

Publications 2000

  1. Bukholm IK, Nesland JM, Børresen-Dale AL (2000)
    Re-expression of E-cadherin, alpha-catenin and beta-catenin, but not of gamma-catenin, in metastatic tissue from breast cancer patients [seecomments]
    J Pathol, 190 (1), 15-9
    PubMed 10640987
  2. Helland A, Kraggerud SM, Kristensen GB, Holm R, Abeler VM, Huebner K, Borresen-Dale AL, Lothe RA (2000)
    Primary cervical carcinomas show 2 common regions of deletion at 3P, 1 within the FHIT gene: evaluation of allelic imbalance at FHIT, RB1 and TP53 in relation to survival
    Int J Cancer, 88 (2), 217-22
    PubMed 11004671
  3. Hellström AC, Blegen H, Malec M, Silfverswärd C, Lystad S, Børresen-Dale AL, Auer G (2000)
    Recurrent fallopian tube carcinoma: TP53 mutation and clinical course
    Int J Gynecol Pathol, 19 (2), 145-51
    PubMed 10782411
  4. Hou SM, Ryberg D, Fält S, Deverill A, Tefre T, Børresen AL, Haugen A, Lambert B (2000)
    GSTM1 and NAT2 polymorphisms in operable and non-operable lung cancer patients
    Carcinogenesis, 21 (1), 49-54
    PubMed 10607733
  5. Jugessur A, Frost P, Andersen TI, Steine S, Lindblom A, Børresen-Dale AL, Eiken HG (2000)
    Enhanced detection of mutations in BRCA1 exon 11 using restriction endonuclease fingerprinting-single-strand conformation polymorphism
    J Mol Med (Berl), 78 (10), 580-7
    PubMed 11199332
  6. Kolpakova E, Frengen E, Stokke T, Olsnes S (2000)
    Organization, chromosomal localization and promoter analysis of the gene encoding human acidic fibroblast growth factor intracellular binding protein
    Biochem J, 352 Pt 3, 629-35
    PubMed 11104667
  7. Kristensen VN, Borresen-Dale AL (2000)
    Molecular epidemiology of breast cancer: genetic variation in steroid hormone metabolism
    Mutat Res, 462 (2-3), 323-33
    PubMed 10767642
  8. Kristensen VN, Harada N, Yoshimura N, Haraldsen E, Lonning PE, Erikstein B, Kåresen R, Kristensen T, Børresen-Dale AL (2000)
    Genetic variants of CYP19 (aromatase) and breast cancer risk
    Oncogene, 19 (10), 1329-33
    PubMed 10713674
  9. Liestøl K, Kvittingen EA, Rootwelt H, Dunlop O, Goplen AK, Pedersen JC, Brorson SH, Børresen-Dale AL, Myrvang B, Maehlen J (2000)
    Association between apolipoprotein E genotypes and cancer risk in patients with acquired immunodeficiency syndrome
    Cancer Detect Prev, 24 (5), 496-9
    PubMed 11129992
  10. Laake K, Jansen L, Hahnemann JM, Brondum-Nielsen K, Lönnqvist T, Kääriäinen H, Sankila R, Lähdesmäki A, Hammarström L, Yuen J, Tretli S, Heiberg A, Olsen JH, Tucker M, Kleinerman R, Børresen-Dale AL (2000)
    Characterization of ATM mutations in 41 Nordic families with ataxia telangiectasia
    Hum Mutat, 16 (3), 232-46
    PubMed 10980530
  11. Laake K, Vu P, Andersen TI, Erikstein B, Kåresen R, Lonning PE, Skovlund E, Børresen-Dale AL (2000)
    Screening breast cancer patients for Norwegian ATM mutations
    Br J Cancer, 83 (12), 1650-3
    PubMed 11104561
  12. Osoegawa K, Tateno M, Woon PY, Frengen E, Mammoser AG, Catanese JJ, Hayashizaki Y, de Jong PJ (2000)
    Bacterial artificial chromosome libraries for mouse sequencing and functional analysis
    Genome Res, 10 (1), 116-28
    PubMed 10645956
  13. Perou CM, Sørlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lønning PE, Børresen-Dale AL, Brown PO, Botstein D (2000)
    Molecular portraits of human breast tumours
    Nature, 406 (6797), 747-52
    PubMed 10963602
  14. Stokke T, Galteland E, Holte H, Smedshammer L, Suo Z, Smeland EB, Børresen-Dale AL, DeAngelis P, Steen HB (2000)
    Oncogenic aberrations in the p53 pathway are associated with a high S phase fraction and poor patient survival in B-cell Non-Hodgkin's lymphoma
    Int J Cancer, 89 (4), 313-24
    PubMed 10956404

Publications 1999

  1. Arver B, Claro A, Langerød A, Børresen-Dale AL, Lindblom A (1999)
    BRCA1 screening in patients with a family history of breast or ovarian cancer
    Genet Test, 3 (2), 223-6
    PubMed 10464672
  2. Berner JM, Sørlie T, Mertens F, Henriksen J, Saeter G, Mandahl N, Brøgger A, Myklebost O, Lothe RA (1999)
    Chromosome band 9p21 is frequently altered in malignant peripheral nerve sheath tumors: studies of CDKN2A and other genes of the pRB pathway
    Genes Chromosomes Cancer, 26 (2), 151-60
    PubMed 10469453
  3. Danielsen T, Smith-Sørensen B, Grønlund HA, Hvidsten M, Børresen-Dale AL, Rofstad EK (1999)
    No association between radiosensitivity and TP53 status, G1 arrest or protein levels of p53, myc, ras or raf in human melanoma lines
    Int J Radiat Biol, 75 (9), 1149-60
    PubMed 10528923
  4. Ekstrøm PO, Børresen-Dale AL, Qvist H, Giercksky KE, Thilly WG (1999)
    Detection of low-frequency mutations in exon 8 of the TP53 gene by constant denaturant capillary electrophoresis (CDCE)
    Biotechniques, 27 (1), 128-34
    PubMed 10407675
  5. Graphodatsky AS, Vorobieva NV, Filipenko ML, Voronina EV, Frengen E, Prydz H (1999)
    Assignment of the L11 ribosomal protein gene (RPL11) to human chromosome 1p36.1-->p35 by in situ hybridization
    Cytogenet Cell Genet, 84 (1-2), 97-8
    PubMed 10343117
  6. Helland A, Børresen-Dale AL (1999)
    p53 polymorphism and cervical cancer
    Lancet, 354 (9189), 1561-2
    PubMed 10551531
  7. Högmo A, Börresen-Dale AL, Blegen H, Lindholm J, Kuylenstierna R, Auer G, Munck-Wikland E (1999)
    TP53 mutations do not correlate with locoregional recurrence in stage I tongue carcinomas
    Anticancer Res, 19 (4C), 3433-8
    PubMed 10629631
  8. Laake K, Launonen V, Niederacher D, Gudlaugsdottir S, Seitz S, Rio P, Champème MH, Bièche I, Birnbaum D, White G, Sztan M, Sever N, Plummer S, Osorio A, Broeks A, Huusko P, Spurr N, Borg A, Cleton-Jansen AM, van't Veer L, Benitez J, Casey G, Peterlin B, Olah E, Børresen-Dale AL (1999)
    Loss of heterozygosity at 11q23.1 and survival in breast cancer: results of a large European study. Breast Cancer Somatic Genetics Consortium
    Genes Chromosomes Cancer, 25 (3), 212-21
    PubMed 10379867
  9. Matre V, Høvring PI, Orstavik S, Frengen E, Rian E, Velickovic Z, Murray-McIntosh RP, Gautvik KM (1999)
    Structural and functional organization of the gene encoding the human thyrotropin-releasing hormone receptor
    J Neurochem, 72 (1), 40-50
    PubMed 9886052
  10. Nedelcheva Kristensen V, Haraldsen EK, Anderson KB, Lønning PE, Erikstein B, Kåresen R, Gabrielsen OS, Børresen-Dale AL (1999)
    CYP17 and breast cancer risk: the polymorphism in the 5' flanking area of the gene does not influence binding to Sp-1
    Cancer Res, 59 (12), 2825-8
    PubMed 10383140
  11. Rødningen OK, Tonstad S, Saugstad OD, Ose L, Leren TP (1999)
    Mutant transcripts of the LDL receptor gene: mRNA structure and quantity
    Hum Mutat, 13 (3), 186-96
    PubMed 10090473
  12. Skammelsrud N, Martin ER, Murphy P, Khuu C, Frengen E, Kolstø AB (1999)
    The gene for human transcription factor TCF11 is located telomeric to D17S1827, BTR and HP1Hsbeta on chromosome 17q22
    Genet Anal, 15 (6), 217-22
    PubMed 10609757
  13. Skomedal H, Helland A, Kristensen GB, Holm R, Børresen-Dale AL (1999)
    Allelic imbalance at chromosome region 11q23 in cervical carcinomas
    Eur J Cancer, 35 (4), 659-63
    PubMed 10492643
  14. Skomedal H, Kristensen GB, Nesland JM, Børresen-Dale AL, Tropé C, Holm R (1999)
    TP53 alterations in relation to the cell cycle-associated proteins p21, cyclin D1, CDK4, RB, MDM2, and EGFR in cancers of the uterine corpus
    J Pathol, 187 (5), 556-62
    PubMed 10398121
  15. van Slooten HJ, van De Vijver MJ, Borresen AL, Eyfjörd JE, Valgardsdóttir R, Scherneck S, Nesland JM, Devilee P, Cornelisse CJ, van Dierendonck JH (1999)
    Mutations in exons 5-8 of the p53 gene, independent of their type and location, are associated with increased apoptosis and mitosis in invasive breast carcinoma
    J Pathol, 189 (4), 504-13
    PubMed 10629550

Publications 1998

  1. Adélaïde J, Chaffanet M, Imbert A, Allione F, Geneix J, Popovici C, van Alewijk D, Trapman J, Zeillinger R, Børresen-Dale AL, Lidereau R, Birnbaum D, Pébusque MJ (1998)
    Chromosome region 8p11-p21: refined mapping and molecular alterations in breast cancer
    Genes Chromosomes Cancer, 22 (3), 186-99
    PubMed 9624530
  2. Andersen TI, Børresen-Dale AL (1998)
    [Diagnostic molecular biology in breast cancer]
    Tidsskr Nor Laegeforen, 118 (15), 2366-9
    PubMed 9691806
  3. Andersen TI, Eiken HG, Couch F, Kaada G, Skrede M, Johnsen H, Aloysius TA, Tveit KM, Tranebjaerg L, Dørum A, Møller P, Weber BL, Børresen-Dale AL (1998)
    Constant denaturant gel electrophoresis (CDGE) in BRCA1 mutation screening
    Hum Mutat, 11 (2), 166-74
    PubMed 9482581
  4. Bjørheim J, Lystad S, Lindblom A, Kressner U, Westring S, Wahlberg S, Lindmark G, Gaudernack G, Ekstrøm P, Røe J, Thilly WG, Børresen-Dale AL (1998)
    Mutation analyses of KRAS exon 1 comparing three different techniques: temporal temperature gradient electrophoresis, constant denaturant capillary electrophoresis and allele specific polymerase chain reaction
    Mutat Res, 403 (1-2), 103-12
    PubMed 9726011
  5. Bukholm IK, Berner JM, Nesland JM, Børresen-Dale AL (1998)
    Expression of cyclin Ds in relation to p53 status in human breast carcinomas
    Virchows Arch, 433 (3), 223-8
    PubMed 9769125
  6. Bukholm IK, Nesland JM, Kåresen R, Jacobsen U, Børresen-Dale AL (1998)
    E-cadherin and alpha-, beta-, and gamma-catenin protein expression in relation to metastasis in human breast carcinoma
    J Pathol, 185 (3), 262-6
    PubMed 9771479
  7. Børresen-Dale AL, Lothe RA, Meling GI, Hainaut P, Rognum TO, Skovlund E (1998)
    TP53 and long-term prognosis in colorectal cancer: mutations in the L3 zinc-binding domain predict poor survival
    Clin Cancer Res, 4 (1), 203-10
    PubMed 9516972
  8. Clausen OP, Lothe RA, Børresen-Dale AL, De Angelis P, Chen Y, Rognum TO, Meling GI (1998)
    Association of p53 accumulation with TP53 mutations, loss of heterozygosity at 17p13, and DNA ploidy status in 273 colorectal carcinomas
    Diagn Mol Pathol, 7 (4), 215-23
    PubMed 9917132
  9. Eiken HG, Børresen-Dale AL (1998)
    [Molecular genetic diagnostics. Technology for detecting mutations in DNA]
    Tidsskr Nor Laegeforen, 118 (11), 1730-6
    PubMed 9621763
  10. Helland A, Langerød A, Johnsen H, Olsen AO, Skovlund E, Børresen-Dale AL (1998)
    p53 polymorphism and risk of cervical cancer
    Nature, 396 (6711), 530-1; author reply 532
    PubMed 9859987
  11. Helland A, Olsen AO, Gjøen K, Akselsen HE, Sauer T, Magnus P, Børresen-Dale AL, Rønningen KS (1998)
    An increased risk of cervical intra-epithelial neoplasia grade II-III among human papillomavirus positive patients with the HLA-DQA1*0102-DQB1*0602 haplotype: a population-based case-control study of Norwegian women
    Int J Cancer, 76 (1), 19-24
    PubMed 9533756
  12. Kressner U, Bjørheim J, Westring S, Wahlberg SS, Påhlman L, Glimelius B, Lindmark G, Lindblom A, Børresen-Dale AL (1998)
    Ki-ras mutations and prognosis in colorectal cancer
    Eur J Cancer, 34 (4), 518-21
    PubMed 9713302
  13. Kristensen T, Kristensen VN, Børresen-Dale AL (1998)
    High-throughput screening for known mutations by automated analysis of single sequencing reactions
    Biotechniques, 24 (5), 832-5
    PubMed 9591134
  14. Kristensen VN, Andersen TI, Lindblom A, Erikstein B, Magnus P, Børresen-Dale AL (1998)
    A rare CYP19 (aromatase) variant may increase the risk of breast cancer
    Pharmacogenetics, 8 (1), 43-8
    PubMed 9511180
  15. Lothe RA, Hektoen M, Johnsen H, Meling GI, Andersen TI, Rognum TO, Lindblom A, Børresen-Dale AL (1998)
    The APC gene I1307K variant is rare in Norwegian patients with familial and sporadic colorectal or breast cancer
    Cancer Res, 58 (14), 2923-4
    PubMed 9679946
  16. Laake K, Telatar M, Geitvik GA, Hansen RO, Heiberg A, Andresen AM, Gatti R, Børresen-Dale AL (1998)
    Identical mutation in 55% of the ATM alleles in 11 Norwegian AT families: evidence for a founder effect
    Eur J Hum Genet, 6 (3), 235-44
    PubMed 9781027
  17. Nedelcheva Kristensen V, Andersen TI, Erikstein B, Geitvik G, Skovlund E, Nesland JM, Børresen-Dale AL (1998)
    Single tube multiplex polymerase chain reaction genotype analysis of GSTM1, GSTT1 and GSTP1: relation of genotypes to TP53 tumor status and clinicopathological variables in breast cancer patients
    Pharmacogenetics, 8 (5), 441-7
    PubMed 9825836
  18. Phelan CM, Borg A, Cuny M, Crichton DN, Baldersson T, Andersen TI, Caligo MA, Lidereau R, Lindblom A, Seitz S, Kelsell D, Hamann U, Rio P, Thorlacius S, Papp J, Olah E, Ponder B, Bignon YJ, Scherneck S, Barkardottir R, Borresen-Dale AL, Eyfjörd J, Theillet C, Thompson AM, Larsson C (1998)
    Consortium study on 1280 breast carcinomas: allelic loss on chromosome 17 targets subregions associated with family history and clinical parameters
    Cancer Res, 58 (5), 1004-12
    PubMed 9500463
  19. Smith-Sørensen B, Kaern J, Holm R, Dørum A, Tropé C, Børresen-Dale AL (1998)
    Therapy effect of either paclitaxel or cyclophosphamide combination treatment in patients with epithelial ovarian cancer and relation to TP53 gene status
    Br J Cancer, 78 (3), 375-81
    PubMed 9703286
  20. Sørlie T, Andersen TI, Bukholm I, Børresen-Dale AL (1998)
    Mutation screening of BRCA1 using PTT and LOH analysis at 17q21 in breast carcinomas from familial and non-familial cases
    Breast Cancer Res Treat, 48 (3), 259-64
    PubMed 9598872
  21. Sørlie T, Bukholm I, Børresen-Dale AL (1998)
    Truncating somatic mutation in exon 15 of the APC gene is a rare event in human breast carcinomas. Mutations in brief no. 179. Online
    Hum Mutat, 12 (3), 215
    PubMed 10660330
  22. Sørlie T, Martel-Planche G, Hainaut P, Lewalter J, Holm R, Børresen-Dale AL, Montesano R (1998)
    Analysis of p53, p16MTS, p21WAF1 and H-ras in archived bladder tumours from workers exposed to aromatic amines
    Br J Cancer, 77 (10), 1573-9
    PubMed 9635831
  23. Telatar M, Teraoka S, Wang Z, Chun HH, Liang T, Castellvi-Bel S, Udar N, Borresen-Dale AL, Chessa L, Bernatowska-Matuszkiewicz E, Porras O, Watanabe M, Junker A, Concannon P, Gatti RA (1998)
    Ataxia-telangiectasia: identification and detection of founder-effect mutations in the ATM gene in ethnic populations
    Am J Hum Genet, 62 (1), 86-97
    PubMed 9443866

Publications 1997

  1. Anderson TI, Wooster R, Laake K, Collins N, Warren W, Skrede M, Elles R, Tveit KM, Johnston SR, Dowsett M, Olsen AO, Møller P, Stratton MR, Børresen-Dale AL (1997)
    Screening for ESR mutations in breast and ovarian cancer patients
    Hum Mutat, 9 (6), 531-6
    PubMed 9195227
  2. Breivik J, Lothe RA, Meling GI, Rognum TO, Børresen-Dale AL, Gaudernack G (1997)
    Different genetic pathways to proximal and distal colorectal cancer influenced by sex-related factors
    Int J Cancer, 74 (6), 664-9
    PubMed 9421366
  3. Bukholm IK, Nesland JM, Kåresen R, Jacobsen U, Børresen-Dale AL (1997)
    Interaction between bcl-2 and p21 (WAF1/CIP1) in breast carcinomas with wild-type p53
    Int J Cancer, 73 (1), 38-41
    PubMed 9334807
  4. Bukholm IK, Nesland JM, Kåresen R, Jacobsen U, Børresen-Dale AL (1997)
    Expression of E-cadherin and its relation to the p53 protein status in human breast carcinomas
    Virchows Arch, 431 (5), 317-21
    PubMed 9463572
  5. Bukholm IK, Nesland JM, Kåresen R, Jacobsen U, Børresen AL (1997)
    Relationship between abnormal p53 protein and failure to express p21 protein in human breast carcinomas
    J Pathol, 181 (2), 140-5
    PubMed 9120716
  6. Devilee P, Hermans J, Eyfjörd J, Bøorresen AL, Lidereau R, Sobol H, Borg A, Cleton-Jansen AM, Oláh E, Cohen BB, Scherneck S, Hamann U, Peterlin B, Caligo M, Bignon YJ, Maugard C (1997)
    Loss of heterozygosity at 7q31 in breast cancer: results from an International Collaborative Study Group. The Breast Cancer Somatic Genetics Consortium
    Genes Chromosomes Cancer, 18 (3), 193-9
    PubMed 9071572
  7. Ellis PA, Lonning PE, Borresen-Dale A, Aas T, Geisler S, Akslen LA, Salter I, Smith IE, Dowsett M (1997)
    Absence of p21 expression is associated with abnormal p53 in human breast carcinomas
    Br J Cancer, 76 (4), 480-5
    PubMed 9275025
  8. Heimdal K, Olsson H, Tretli S, Fosså SD, Børresen AL, Bishop DT (1997)
    A segregation analysis of testicular cancer based on Norwegian and Swedish families
    Br J Cancer, 75 (7), 1084-7
    PubMed 9083348
  9. Helland A, Børresen-Dale AL, Peltomäki P, Hektoen M, Kristensen GB, Nesland JM, de la Chapelle A, Lothe RA (1997)
    Microsatellite instability in cervical and endometrial carcinomas
    Int J Cancer, 70 (5), 499-501
    PubMed 9052745
  10. Kraggerud SM, Jacobsen KD, Berner A, Stokke T, Holm R, Smedshammer L, Børresen-Dale AL, Fosså SD (1997)
    A comparison of different modes for the detection of p53 protein accumulation. A study of bladder cancer
    Pathol Res Pract, 193 (7), 471-8
    PubMed 9342752
  11. Kristensen VN, Børresen-Dale AL (1997)
    Improved electrophoretic separation of polymorphic short tandem repeats in agarose gels using bis-benzimide
    Biotechniques, 23 (4), 634-6
    PubMed 9343680
  12. Laake K, Odegård A, Andersen TI, Bukholm IK, Kåresen R, Nesland JM, Ottestad L, Shiloh Y, Børresen-Dale AL (1997)
    Loss of heterozygosity at 11q23.1 in breast carcinomas: indication for involvement of a gene distal and close to ATM
    Genes Chromosomes Cancer, 18 (3), 175-80
    PubMed 9071570
  13. Paulsen T, Aas T, Børresen AL, Varhaug JE, Lønning PE, Akslen LA (1997)
    Angiogenesis does not predict clinical response to doxorubicin monotherapy in patients with locally advanced breast cancer
    Int J Cancer, 74 (1), 138-40
    PubMed 9036883
  14. Skomedal H, Kristensen GB, Abeler VM, Børresen-Dale AL, Tropé C, Holm R (1997)
    TP53 protein accumulation and gene mutation in relation to overexpression of MDM2 protein in ovarian borderline tumours and stage I carcinomas
    J Pathol, 181 (2), 158-65
    PubMed 9120719
  15. Tranebjaerg L, Børresen-Dale AL, Hansteen IL, Heim S, Kvittingen EA, Møller P (1997)
    Genetic services in Norway
    Eur J Hum Genet, 5 Suppl 2, 130-4
    PubMed 9450210
  16. Zelada-Hedman M, Børresen-Dale AL, Claro A, Chen J, Skoog L, Lindblom A (1997)
    Screening for TP53 mutations in patients and tumours from 109 Swedish breast cancer families
    Br J Cancer, 75 (8), 1201-4
    PubMed 9099970
  17. Zelada-Hedman M, Børresen-Dale AL, Lindblom A (1997)
    Screening of 229 family cancer patients for a germline estrogen receptor gene (ESR) base mutation
    Hum Mutat, 9 (3), 289
    PubMed 9090537
  18. Zelada-Hedman M, Wasteson Arver B, Claro A, Chen J, Werelius B, Kok H, Sandelin K, Håkansson S, Andersen TI, Borg A, Børresen Dale AL, Lindblom A (1997)
    A screening for BRCA1 mutations in breast and breast-ovarian cancer families from the Stockholm region
    Cancer Res, 57 (12), 2474-7
    PubMed 9192828

Publications 1996

  1. Andersen TI, Børresen AL, Møller P (1996)
    A common BRCA1 mutation in Norwegian breast and ovarian cancer families?
    Am J Hum Genet, 59 (2), 486-7
    PubMed 8755943
  2. Chitemerere M, Andersen TI, Holm R, Karlsen F, Børresen AL, Nesland JM (1996)
    TP53 alterations in atypical ductal hyperplasia and ductal carcinoma in situ of the breast
    Breast Cancer Res Treat, 41 (2), 103-9
    PubMed 8944328
  3. Heimdal K, Olsson H, Tretli S, Flodgren P, Børresen AL, Fossa SD (1996)
    Familial testicular cancer in Norway and southern Sweden
    Br J Cancer, 73 (7), 964-9
    PubMed 8611416
  4. Heimdal K, Olsson H, Tretli S, Flodgren P, Børresen AL, Fossa SD (1996)
    Risk of cancer in relatives of testicular cancer patients
    Br J Cancer, 73 (7), 970-3
    PubMed 8611417
  5. Lothe RA, Karhu R, Mandahl N, Mertens F, Saeter G, Heim S, Borresen-Dale AL, Kallioniemi OP (1996)
    Gain of 17q24-qter detected by comparative genomic hybridization in malignant tumors from patients with von Recklinghausen's neurofibromatosis
    Cancer Res, 56 (20), 4778-81
    PubMed 8840998
  6. Maelandsmo GM, Flørenes VA, Hovig E, Oyjord T, Engebraaten O, Holm R, Børresen AL, Fodstad O (1996)
    Involvement of the pRb/p16/cdk4/cyclin D1 pathway in the tumorigenesis of sporadic malignant melanomas
    Br J Cancer, 73 (8), 909-16
    PubMed 8611425
  7. Zedenius J, Larsson C, Wallin G, Bäckdahl M, Aspenblad U, Höög A, Børresen AL, Auer G (1996)
    Alterations of p53 and expression of WAF1/p21 in human thyroid tumors
    Thyroid, 6 (1), 1-9
    PubMed 8777377
  8. Aas T, Børresen AL, Geisler S, Smith-Sørensen B, Johnsen H, Varhaug JE, Akslen LA, Lønning PE (1996)
    Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients
    Nat Med, 2 (7), 811-4
    PubMed 8673929
  9. Aas T, Geisler S, Paulsen T, Børresen-Dale AL, Varhaug JE, Lønning PE, Akslen LA (1996)
    Primary systemic treatment with weekly doxorubicin monotherapy in women with locally advanced breast cancer; clinical experience and parameters predicting outcome
    Acta Oncol, 35 Suppl 5, 5-8
    PubMed 9142957

Publications 1995

  1. Andersen TI, Børresen AL (1995)
    Alterations of the TP53 gene as a potential prognostic marker in breast carcinomas. Advantages of using constant denaturant gel electrophoresis in mutation detection
    Diagn Mol Pathol, 4 (3), 203-11
    PubMed 7493140
  2. Andersen TI, Paus E, Nesland JM, McKenzie SJ, Børresen AL (1995)
    Detection of c-erbB-2 related protein in sera from breast cancer patients. Relationship to ERBB2 gene amplification and c-erbB-2 protein overexpression in tumour
    Acta Oncol, 34 (4), 499-504
    PubMed 7605658
  3. Berner A, Geitvik G, Karlsen F, Fosså SD, Nesland JM, Børresen AL (1995)
    TP53 mutations in prostatic cancer. Analysis of pre- and post-treatment archival formalin-fixed tumour tissue
    J Pathol, 176 (3), 299-308
    PubMed 7674092
  4. Børresen AL, Andersen TI, Eyfjörd JE, Cornelis RS, Thorlacius S, Borg A, Johansson U, Theillet C, Scherneck S, Hartman S (1995)
    TP53 mutations and breast cancer prognosis: particularly poor survival rates for cases with mutations in the zinc-binding domains
    Genes Chromosomes Cancer, 14 (1), 71-5
    PubMed 8527388
  5. Børresen AL, Lothe RA, Meling GI, Lystad S, Morrison P, Lipford J, Kane MF, Rognum TO, Kolodner RD (1995)
    Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas
    Hum Mol Genet, 4 (11), 2065-72
    PubMed 8589682
  6. Esteve A, Sørlie T, Martel-Planche G, Hollstein M, Kusters I, Lewalter J, Vineis P, Stephan-Odenthal M, Montesano R (1995)
    Screening for p53 gene mutations in archived tumors of workers occupationally exposed to carcinogens: examples from analysis of bladder tumors
    J Occup Environ Med, 37 (1), 59-68
    PubMed 7620944
  7. Friend S, Borresen AL, Brody L, Casey G, Devilee P, Gayther S, Goldgar D, Murphy P, Weber BL, Wiseman R (1995)
    Breast cancer information on the web
    Nat Genet, 11 (3), 238-9
    PubMed 7581445
  8. Heimdal K, Andersen TI, Skrede M, Fosså SD, Berg K, Børresen AL (1995)
    Association studies of estrogen receptor polymorphisms in a Norwegian testicular cancer population
    Cancer Epidemiol Biomarkers Prev, 4 (2), 123-6
    PubMed 7742719
  9. Lange E, Borresen AL, Chen X, Chessa L, Chiplunkar S, Concannon P, Dandekar S, Gerken S, Lange K, Liang T (1995)
    Localization of an ataxia-telangiectasia gene to an approximately 500-kb interval on chromosome 11q23.1: linkage analysis of 176 families by an international consortium
    Am J Hum Genet, 57 (1), 112-9
    PubMed 7611279
  10. Lothe RA, Andersen SN, Hofstad B, Meling GI, Peltomäki P, Heim S, Brøgger A, Vatn M, Rognum TO, Børresen AL (1995)
    Deletion of 1p loci and microsatellite instability in colorectal polyps
    Genes Chromosomes Cancer, 14 (3), 182-8
    PubMed 8589034
  11. Lothe RA, Børresen AL (1995)
    [Early diagnosis of colorectal tumors]
    Tidsskr Nor Laegeforen, 115 (26), 3231-2
    PubMed 7482447
  12. Lothe RA, Peltomäki P, Tommerup N, Fosså SD, Stenwig AE, Børresen AL, Nesland JM (1995)
    Molecular genetic changes in human male germ cell tumors
    Lab Invest, 73 (5), 606-14
    PubMed 7474934
  13. Lothe RA, Slettan A, Saeter G, Brøgger A, Børresen AL, Nesland JM (1995)
    Alterations at chromosome 17 loci in peripheral nerve sheath tumors
    J Neuropathol Exp Neurol, 54 (1), 65-73
    PubMed 7815081
  14. Skomedal H, Kristensen G, Helland A, Nesland JM, Kooi S, Børresen AL, Holm R (1995)
    TP53 gene mutations and protein accumulation in primary vaginal carcinomas
    Br J Cancer, 72 (1), 129-33
    PubMed 7599041
  15. Steen VM, Andreassen OA, Daly AK, Tefre T, Børresen AL, Idle JR, Gulbrandsen AK (1995)
    Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology
    Pharmacogenetics, 5 (4), 215-23
    PubMed 8528268
  16. Thorlacius S, Thorgilsson B, Björnsson J, Tryggvadottir L, Börresen AL, Ogmundsdottir HM, Eyfjörd JE (1995)
    TP53 mutations and abnormal p53 protein staining in breast carcinomas related to prognosis
    Eur J Cancer, 31A (11), 1856-61
    PubMed 8541113

Publications 1994

  1. Andersen TI, Heimdal KR, Skrede M, Tveit K, Berg K, Børresen AL (1994)
    Oestrogen receptor (ESR) polymorphisms and breast cancer susceptibility
    Hum Genet, 94 (6), 665-70
    PubMed 7989041
  2. Cornelis RS, van Vliet M, Vos CB, Cleton-Jansen AM, van de Vijver MJ, Peterse JL, Khan PM, Børresen AL, Cornelisse CJ, Devilee P (1994)
    Evidence for a gene on 17p13.3, distal to TP53, as a target for allele loss in breast tumors without p53 mutations
    Cancer Res, 54 (15), 4200-6
    PubMed 8033152
  3. Flørenes VA, Oyjord T, Holm R, Skrede M, Børresen AL, Nesland JM, Fodstad O (1994)
    TP53 allele loss, mutations and expression in malignant melanoma
    Br J Cancer, 69 (2), 253-9
    PubMed 7905277
  4. Gatti RA, Lange E, Rotman G, Chen X, Uhrhammer N, Liang T, Chiplunkar S, Yang L, Udar N, Dandekar S, Sheikhavandi S, Wang Z, Yang HM, Polikow J, Elashoff M, Teletar M, Sanal O, Chessa L, McConville C, Taylor M, Shiloh Y, Porras O, Borresen AL, Wegner RD, Curry C et al. (1994)
    Genetic haplotyping of ataxia-telangiectasia families localizes the major gene to an ~850 kb region on chromosome 11 q23.1
    Int J Radiat Biol, 66 (sup5), S57-S62
    PubMed 27687106
  5. Gatti RA, Lange E, Rotman G, Chen X, Uhrhammer N, Liang T, Chiplunkar S, Yang L, Udar N, Dandekar S, Sheikhavandi S, Wang Z, Yang HM, Polikow J, Elashoff M, Teletar M, Sanal O, Chessa L, McConville C, Taylor M, Shiloh Y, Porras O, Borresen AL, Wegner RD, Curry C et al. (1994)
    Genetic haplotyping of ataxia-telangiectasia families localizes the major gene to an approximately 850 kb region on chromosome 11q23.1
    Int J Radiat Biol, 66 (6 Suppl), S57-62
    PubMed 7836853
  6. Heimdal KR, Lothe RA, Fosså SD, Børresen AL (1994)
    Association studies of a polymorphism in the Wilms' tumor 1 locus in Norwegian patients with testicular cancer
    Int J Cancer, 58 (4), 523-6
    PubMed 8056449
  7. Helland A, Børresen AL, Kristensen G, Rønningen KS (1994)
    DQA1 and DQB1 genes in patients with squamous cell carcinoma of the cervix: relationship to human papillomavirus infection and prognosis
    Cancer Epidemiol Biomarkers Prev, 3 (6), 479-86
    PubMed 8000298
  8. Hollstein M, Rice K, Greenblatt MS, Soussi T, Fuchs R, Sørlie T, Hovig E, Smith-Sørensen B, Montesano R, Harris CC (1994)
    Database of p53 gene somatic mutations in human tumors and cell lines
    Nucleic Acids Res, 22 (17), 3551-5
    PubMed 7937055
  9. McIntyre JF, Smith-Sorensen B, Friend SH, Kassell J, Borresen AL, Yan YX, Russo C, Sato J, Barbier N, Miser J (1994)
    Germline mutations of the p53 tumor suppressor gene in children with osteosarcoma
    J Clin Oncol, 12 (5), 925-30
    PubMed 8164043
  10. Nesland JM, Børresen AL, Andersson LC (1994)
    [Molecular pathology. A new diagnostic dimension]
    Tidsskr Nor Laegeforen, 114 (26), 3047-8
    PubMed 7974419
  11. Rosenberg C, Andersen TI, Nesland JM, Lier ME, Brøgger A, Børresen AL (1994)
    Genetic alterations of chromosome 17 in human breast carcinoma studied by fluorescence in situ hybridization and molecular DNA techniques
    Cancer Genet Cytogenet, 75 (1), 1-5
    PubMed 8039157
  12. Rosenberg C, Janson M, Nordeskjöld M, Børresen AL, Vianna-Morgante AM (1994)
    Intragenic reorganization of RB1 in a complex (4;13) rearrangement demonstrated by FISH
    Cytogenet Cell Genet, 65 (4), 268-71
    PubMed 8258302
  13. Ryberg D, Kure E, Lystad S, Skaug V, Stangeland L, Mercy I, Børresen AL, Haugen A (1994)
    p53 mutations in lung tumors: relationship to putative susceptibility markers for cancer
    Cancer Res, 54 (6), 1551-5
    PubMed 8137262
  14. Seruca R, David L, Castedo S, Veiga I, Børresen AL, Sobrinho-Simões M (1994)
    p53 alterations in gastric carcinoma: a study of 56 primary tumors and 204 nodal metastases
    Cancer Genet Cytogenet, 75 (1), 45-50
    PubMed 8039163
  15. Tefre T, Daly AK, Armstrong M, Leathart JB, Idle JR, Brøgger A, Børresen AL (1994)
    Genotyping of the CYP2D6 gene in Norwegian lung cancer patients and controls
    Pharmacogenetics, 4 (2), 47-57
    PubMed 8081413
  16. Verwest AM, de Leeuw WJ, Molijn AC, Andersen TI, Börresen AL, Mullaart E, Uitterlinden AG, Vijg J (1994)
    Genome scanning of breast cancers by two-dimensional DNA typing
    Br J Cancer, 69 (1), 84-92
    PubMed 8286216

Publications 1993

  1. Andersen TI, Holm R, Nesland JM, Heimdal KR, Ottestad L, Børresen AL (1993)
    Prognostic significance of TP53 alterations in breast carcinoma
    Br J Cancer, 68 (3), 540-8
    PubMed 8102535
  2. Andreassen A, Oyjord T, Hovig E, Holm R, Flørenes VA, Nesland JM, Myklebost O, Høie J, Bruland OS, Børresen AL (1993)
    p53 abnormalities in different subtypes of human sarcomas
    Cancer Res, 53 (3), 468-71
    PubMed 8425179
  3. Condie A, Eeles R, Borresen AL, Coles C, Cooper C, Prosser J (1993)
    Detection of point mutations in the p53 gene: comparison of single-strand conformation polymorphism, constant denaturant gel electrophoresis, and hydroxylamine and osmium tetroxide techniques
    Hum Mutat, 2 (1), 58-66
    PubMed 8477265
  4. Heimdal K, Lothe RA, Lystad S, Holm R, Fosså SD, Børresen AL (1993)
    No germline TP53 mutations detected in familial and bilateral testicular cancer
    Genes Chromosomes Cancer, 6 (2), 92-7
    PubMed 7680893
  5. Helland A, Holm R, Kristensen G, Kaern J, Karlsen F, Trope C, Nesland JM, Børresen AL (1993)
    Genetic alterations of the TP53 gene, p53 protein expression and HPV infection in primary cervical carcinomas
    J Pathol, 171 (2), 105-14
    PubMed 8283348
  6. Holm R, Skomedal H, Helland A, Kristensen G, Børresen AL, Nesland JM (1993)
    Immunohistochemical analysis of p53 protein overexpression in normal, premalignant, and malignant tissues of the cervix uteri
    J Pathol, 169 (1), 21-6
    PubMed 8433212
  7. Hovig E, Mullaart E, Børresen AL, Uitterlinden AG, Vijg J (1993)
    Genome scanning of human breast carcinomas using micro- and minisatellite core probes
    Genomics, 17 (1), 66-75
    PubMed 8104870
  8. Lothe RA, Hastie N, Heimdal K, Fosså SD, Stenwig AE, Børresen AL (1993)
    Frequent loss of 11p13 and 11p15 loci in male germ cell tumours
    Genes Chromosomes Cancer, 7 (2), 96-101
    PubMed 7687459
  9. Lothe RA, Saeter G, Danielsen HE, Stenwig AE, Høyheim B, O'Connell P, Børresen AL (1993)
    Genetic alterations in a malignant schwannoma from a patient with neurofibromatosis (NF1)
    Pathol Res Pract, 189 (4), 465-71; discussion 471-4
    PubMed 8351250
  10. Meling GI, Lothe RA, Børresen AL, Graue C, Hauge S, Clausen OP, Rognum TO (1993)
    The TP53 tumour suppressor gene in colorectal carcinomas. I. Genetic alterations on chromosome 17
    Br J Cancer, 67 (1), 88-92
    PubMed 8094008
  11. Meling GI, Lothe RA, Børresen AL, Graue C, Hauge S, Clausen OP, Rognum TO (1993)
    The TP53 tumour suppressor gene in colorectal carcinomas. II. Relation to DNA ploidy pattern and clinicopathological variables
    Br J Cancer, 67 (1), 93-8
    PubMed 8427784
  12. Ottestad L, Andersen TI, Nesland JM, Skrede M, Tveit KM, Nustad K, Børresen AL (1993)
    Amplification of c-erbB-2, int-2 and c-myc genes in node-negative breast carcinomas. Relationship to prognosis
    Acta Oncol, 32 (3), 289-94
    PubMed 8100712
  13. Ridanpää M, Lothe RA, Onfelt A, Fosså S, Børresen AL, Husgafvel-Pursiainen K (1993)
    K-ras oncogene codon 12 point mutations in testicular cancer
    Environ Health Perspect, 101 Suppl 3, 185-7
    PubMed 8143614
  14. Ryberg D, Heimdal K, Fosså SD, Børresen AL, Haugen A (1993)
    Rare Ha-ras1 alleles and predisposition to testicular cancer
    Int J Cancer, 53 (6), 938-40
    PubMed 8097187
  15. Smith-Sørensen B, Gebhardt MC, Kloen P, McIntyre J, Aguilar F, Cerutti P, Børresen AL (1993)
    Screening for TP53 mutations in osteosarcomas using constant denaturant gel electrophoresis (CDGE)
    Hum Mutat, 2 (4), 274-85
    PubMed 8401536
  16. Thorlacius S, Börresen AL, Eyfjörd JE (1993)
    Somatic p53 mutations in human breast carcinomas in an Icelandic population: a prognostic factor
    Cancer Res, 53 (7), 1637-41
    PubMed 8453635

Publications 1992

  1. Andersen TI, Gaustad A, Ottestad L, Farrants GW, Nesland JM, Tveit KM, Børresen AL (1992)
    Genetic alterations of the tumour suppressor gene regions 3p, 11p, 13q, 17p, and 17q in human breast carcinomas
    Genes Chromosomes Cancer, 4 (2), 113-21
    PubMed 1373310
  2. Børresen AL (1992)
    Role of genetic factors in breast cancer susceptibility
    Acta Oncol, 31 (2), 151-5
    PubMed 1622629
  3. Børresen AL (1992)
    Oncogenesis in ovarian cancer
    Acta Obstet Gynecol Scand Suppl, 155, 25-30
    PubMed 1502889
  4. Børresen AL, Andersen TI, Garber J, Barbier-Piraux N, Thorlacius S, Eyfjörd J, Ottestad L, Smith-Sørensen B, Hovig E, Malkin D (1992)
    Screening for germ line TP53 mutations in breast cancer patients
    Cancer Res, 52 (11), 3234-6
    PubMed 1591732
  5. Børresen AL, Helland A, Nesland J, Holm R, Trope C, Kaern J (1992)
    Papillomaviruses, p53, and cervical cancer
    Lancet, 339 (8805), 1350-1
    PubMed 1350005
  6. David L, Seruca R, Nesland JM, Soares P, Sansonetty F, Holm R, Børresen AL, Sobrinho-Simões M (1992)
    c-erbB-2 expression in primary gastric carcinomas and their metastases
    Mod Pathol, 5 (4), 384-90
    PubMed 1353880
  7. Frebourg T, Kassel J, Lam KT, Gryka MA, Barbier N, Andersen TI, Børresen AL, Friend SH (1992)
    Germ-line mutations of the p53 tumor suppressor gene in patients with high risk for cancer inactivate the p53 protein
    Proc Natl Acad Sci U S A, 89 (14), 6413-7
    PubMed 1631137
  8. Helland A, Børresen AL, Kaern J, Rønningen KS, Thorsby E (1992)
    HLA antigens and cervical carcinoma
    Nature, 356 (6364), 23
    PubMed 1538776
  9. Hovig E, Andreassen A, Fangan BM, Børresen AL (1992)
    A TP53 mutation detected in cells established from an osteosarcoma, but not in the retinoblastoma of a patient with bilateral retinoblastoma and multiple primary osteosarcomas
    Cancer Genet Cytogenet, 64 (2), 178-82
    PubMed 1336709
  10. Hovig E, Smith-Sørensen B, Gebhardt MC, Ryberg D, Lothe R, Børresen AL (1992)
    No alterations in exon 21 of the RB1 gene in sarcomas and carcinomas of the breast, colon, and lung
    Genes Chromosomes Cancer, 5 (2), 97-103
    PubMed 1381957
  11. Hovig E, Smith-Sørensen B, Uitterlinden AG, Børresen AL (1992)
    Detection of DNA variation in cancer
    Pharmacogenetics, 2 (6), 317-28
    PubMed 1306133
  12. Husgafvel-Pursiainen K, Ridanpää M, Hackman P, Anttila S, Karjalainen A, Onfelt A, Børresen AL, Vainio H (1992)
    Detection of ras gene mutations in human lung cancer: comparison of two screening assays based on the polymerase chain reaction
    Environ Health Perspect, 98, 183-5
    PubMed 1486847
  13. Lothe RA, Fossli T, Danielsen HE, Stenwig AE, Nesland JM, Gallie B, Børresen AL (1992)
    Molecular genetic studies of tumor suppressor gene regions on chromosomes 13 and 17 in colorectal tumors
    J Natl Cancer Inst, 84 (14), 1100-8
    PubMed 1619684
  14. Malkin D, Jolly KW, Barbier N, Look AT, Friend SH, Gebhardt MC, Andersen TI, Børresen AL, Li FP, Garber J (1992)
    Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms
    N Engl J Med, 326 (20), 1309-15
    PubMed 1565144
  15. Peltomäki P, Lothe RA, Børresen AL, Fosså SD, Brøgger A, de la Chapelle A (1992)
    Chromosome 12 in human testicular cancer: dosage changes and their parental origin
    Cancer Genet Cytogenet, 64 (1), 21-6
    PubMed 1458445
  16. Ryberg D, Tefre T, Skaug V, Stangeland L, Ovrebø S, Naalsund A, Børresen AL, Haugen A (1992)
    Allele diversity of the H-ras-1 variable number of tandem repeats in Norwegian lung cancer patients
    Environ Health Perspect, 98, 187-9
    PubMed 1362538
  17. Seruca R, David L, Holm R, Nesland JM, Fangan BM, Castedo S, Sobrinho-Simões M, Børresen AL (1992)
    P53 mutations in gastric carcinomas
    Br J Cancer, 65 (5), 708-10
    PubMed 1586599
  18. Smith-Sørensen B, Hovig E, Andersson B, Børresen AL (1992)
    Screening for mutations in human HPRT cDNA using the polymerase chain reaction (PCR) in combination with constant denaturant gel electrophoresis (CDGE)
    Mutat Res, 269 (1), 41-53
    PubMed 1381470

Publications 1991

  1. Børresen AL, Hovig E, Smith-Sørensen B, Malkin D, Lystad S, Andersen TI, Nesland JM, Isselbacher KJ, Friend SH (1991)
    Constant denaturant gel electrophoresis as a rapid screening technique for p53 mutations
    Proc Natl Acad Sci U S A, 88 (19), 8405-9
    PubMed 1924299
  2. Hovig, Eivind, Smith-Sørensen B, Brøgger A, Børrensen AL (1991)
    Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection
    Mutat Res, 263 (1), 61
    PubMed 2034242
  3. Hovig E, Lothe R, Farrants G, Brøgger A, Fodstad O, Børresen AL (1991)
    Chromosome 13 alterations in osteosarcoma cell lines derived from a patient with previous retinoblastoma
    Cancer Genet Cytogenet, 57 (1), 31-40
    PubMed 1684533
  4. Hovig E, Smith-Sørensen B, Brøgger A, Børresen AL (1991)
    Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection
    Mutat Res, 262 (1), 63-71
    PubMed 1702518
  5. Meling GI, Lothe RA, Børresen AL, Hauge S, Graue C, Clausen OP, Rognum TO (1991)
    Genetic alterations within the retinoblastoma locus in colorectal carcinomas. Relation to DNA ploidy pattern studied by flow cytometric analysis
    Br J Cancer, 64 (3), 475-80
    PubMed 1911187
  6. Nesland JM, Ottestad L, Børresen AL, Tvedt KE, Holm R, Heikkilä R, Tveit K (1991)
    The c-erbB-2 protein in primary and metastatic breast carcinomas
    Ultrastruct Pathol, 15 (3), 281-9
    PubMed 1678562
  7. Nesland JM, Ottestad L, Heikilla R, Holm R, Tveit K, Børresen AL (1991)
    C-erbB-2 protein and neuroendocrine expression in breast carcinomas
    Anticancer Res, 11 (1), 161-7
    PubMed 1673329
  8. Peltomäki P, Lothe R, Børresen AL, Fosså SD, Brøgger A, de la Chapelle A (1991)
    Altered dosage of the sex chromosomes in human testicular cancer: a molecular genetic study
    Int J Cancer, 47 (4), 518-22
    PubMed 1995482
  9. Tefre T, Ryberg D, Haugen A, Nebert DW, Skaug V, Brøgger A, Børresen AL (1991)
    Human CYP1A1 (cytochrome P(1)450) gene: lack of association between the Msp I restriction fragment length polymorphism and incidence of lung cancer in a Norwegian population
    Pharmacogenetics, 1 (1), 20-5
    PubMed 1726950

Publications 1990

  1. BORRESEN A (1990)
    THE USE OF GENE TECHNOLOGY IN THE CLINICAL LABORATORY
    Scand. J. Clin. Lab. Invest., 50 202, 9-13
  2. Børresen AL (1990)
    The use of gene technology in the clinical laboratory
    Scand J Clin Lab Invest Suppl, 202, 9-13
    PubMed 2075459
  3. Børresen AL, Andersen TI, Tretli S, Heiberg A, Møller P (1990)
    Breast cancer and other cancers in Norwegian families with ataxia-telangiectasia
    Genes Chromosomes Cancer, 2 (4), 339-40
    PubMed 2268581
  4. Børresen AL, Hovig E, Smith-Sørensen B, Vrieling H, Apold J, Brøgger A (1990)
    Screening for base mutations in the PAH and HPRT loci using the polymerase chain reaction (PCR) in combination with denaturing gradient gel electrophoresis (DGGE)
    Prog Clin Biol Res, 340A, 389-98
    PubMed 2388921
  5. Børresen AL, Ottestad L, Gaustad A, Andersen TI, Heikkilä R, Jahnsen T, Tveit KM, Nesland JM (1990)
    Amplification and protein over-expression of the neu/HER-2/c-erbB-2 protooncogene in human breast carcinomas: relationship to loss of gene sequences on chromosome 17, family history and prognosis
    Br J Cancer, 62 (4), 585-90
    PubMed 1977466
  6. Fosså SD, Langmark F, Aass N, Andersen A, Lothe R, Børresen AL (1990)
    Second non-germ cell malignancies after radiotherapy of testicular cancer with or without chemotherapy
    Br J Cancer, 61 (4), 639-43
    PubMed 2109999
  7. Haugen A, Willey J, Børresen AL, Tefre T (1990)
    PstI polymorphism at the human P1450 gene on chromosome 15
    Nucleic Acids Res, 18 (10), 3114
    PubMed 1971943
  8. Møller P, Moe N, Saugstad OD, Skullerud K, Velken M, Berg K, Nitter-Hauge S, Børresen AL (1990)
    Spinal muscular atrophy type I combined with atrial septal defect in three sibs
    Clin Genet, 38 (2), 81-3
    PubMed 2208769
  9. Ryberg D, Tefre T, Ovrebø S, Skaug V, Stangeland L, Naalsund A, Baera R, Børresen AL, Haugen A (1990)
    Ha-ras-1 alleles in Norwegian lung cancer patients
    Hum Genet, 86 (1), 40-4
    PubMed 1979305
  10. Tefre T, Børresen AL, Aamdal S, Brøgger A (1990)
    Studies of the L-myc DNA polymorphism and relation to metastasis in Norwegian lung cancer patients
    Br J Cancer, 61 (6), 809-12
    PubMed 1973618

Publications 1989

  1. Børresen AL (1989)
    [Gene technology in clinical medicine--technics and tools]
    Tidsskr Nor Laegeforen, 109 (28), 2882-7
    PubMed 2815027
  2. Børresen AL, Berg K (1989)
    [Genetic variation and genetic diseases]
    Tidsskr Nor Laegeforen, 109 (29), 3003-9
    PubMed 2588229
  3. Børresen AL, Brøgger A, Møller P, Smeland E (1989)
    [Gene technology in the prevention of cancer]
    Tidsskr Nor Laegeforen, 109 (33), 3430-4
    PubMed 2609305
  4. Lerner UH, Ransjö M, Sahlberg K, Ljunggren O, Fredholm BB (1989)
    Forskolin sensitizes parathyroid hormone-induced cyclic AMP response, but not the bone resorptive effect, in mouse calvarial bones
    Bone Miner, 5 (2), 169-81
    PubMed 2537671
  5. Lerner UH, Sahlberg K, Ljunggren O (1989)
    Thrombin and bradykinin enhance prostaglandin production in human peripheral blood monocytes
    J Oral Pathol Med, 18 (4), 246-50
    PubMed 2671341
  6. Lothe RA, Fosså SD, Stenwig AE, Nakamura Y, White R, Børresen AL, Brøgger A (1989)
    Loss of 3p or 11p alleles is associated with testicular cancer tumors
    Genomics, 5 (1), 134-8
    PubMed 2767683

Publications 1988

  1. Børresen AL, Hovig E, Brøgger A (1988)
    Detection of base mutations in genomic DNA using denaturing gradient gel electrophoresis (DGGE) followed by transfer and hybridization with gene-specific probes
    Mutat Res, 202 (1), 77-83
    PubMed 2903443

Publications 1987

  1. Børresen AL, Heiberg A, Møller P, Berg K (1987)
    Evidence for a sperm mutation resulting in Duchenne muscular dystrophy
    Clin Genet, 32 (3), 187-91
    PubMed 2887319
  2. Børresen AL, Leren T, Berg K, Solaas MH (1987)
    Effect of haptoglobin subtypes on serum lipid levels
    Hum Hered, 37 (3), 150-6
    PubMed 3583295
  3. Lerner UH, Sahlberg K, Fredholm BB (1987)
    Characterization of adenosine receptors in bone. Studies on the effect of adenosine analogues on cyclic AMP formation and bone resorption in cultured mouse calvaria
    Acta Physiol Scand, 131 (2), 287-96
    PubMed 2823534
  4. Rivrud GN, Hagen I, Børresen AL (1987)
    Mutagenicity testing of human milk from smokers and non-smokers in the Salmonella/microsome test
    Life Sci, 41 (21), 2389-96
    PubMed 3316890
  5. Skjørten F, Bakken J, Halvorsen S, Børresen AL (1987)
    [Fabry's disease detected by renal biopsy]
    Tidsskr Nor Laegeforen, 107 (9), 848, 873
    PubMed 3109070

Publications 1986

  1. Børresen AL (1986)
    RFLPs in collagen loci and disease
    Ann Clin Res, 18 (5-6), 258-63
    PubMed 2882728
  2. Dahl LB, Dahl IM, Børresen AL (1986)
    The molecular weight of sodium hyaluronate in amniotic fluid
    Biochem Med Metab Biol, 35 (2), 219-26
    PubMed 3707753
  3. Tsipouras P, Børresen AL, Bamforth S, Harper PS, Berg K (1986)
    Marfan syndrome: exclusion of genetic linkage to the COL1A2 gene
    Clin Genet, 30 (5), 428-32
    PubMed 2879657

Publications 1985

  1. Børresen AL, Berg K, Tsipouras P, Dickson LA, Prockop DJ, Ramirez F (1985)
    DNA polymorphisms in collagen genes: potential use in the study of disease
    Prog Clin Biol Res, 177, 37-51
    PubMed 2989837
  2. Børresen AL, Jordfald AB, Berg K (1985)
    DNA polymorphism of the RC8 probe on the X-chromosome. Identification of a new DNA variant with the TaqI enzyme
    Clin Genet, 27 (4), 411-3
    PubMed 2986884
  3. Kvittingen EA, Børresen AL, Stokke O, van der Hagen CB, Lie SO (1985)
    Deficiency of fumarylacetoacetase without hereditary tyrosinemia
    Clin Genet, 27 (6), 550-4
    PubMed 4017276
  4. Kvittingen EA, Steinmann B, Gitzelmann R, Leonard JV, Andria G, Børresen AL, Mossman J, Micara G, Lindblad B (1985)
    Prenatal diagnosis of hereditary tyrosinemia by determination of fumarylacetoacetase in cultured amniotic fluid cells
    Pediatr Res, 19 (4), 334-7
    PubMed 4000758
  5. Leren TP, Børresen AL, Berg K, Hjermann I, Leren P (1985)
    Increased frequency of the apolipoprotein E-4 isoform in male subjects with multifactorial hypercholesterolemia
    Clin Genet, 27 (5), 458-62
    PubMed 4006269
  6. Leren TP, Hjermann I, Børresen AL, Berg K, Leren P (1985)
    Maximal low density lipoprotein receptor activity and the effect of lipid lowering diet on total serum cholesterol
    Clin Genet, 27 (6), 543-9
    PubMed 4017275

Publications 1984

  1. Humphries SE, Berg K, Gill L, Cumming AM, Robertson FW, Stalenhoef AF, Williamson R, Børresen AL (1984)
    The gene for apolipoprotein C-II is closely linked to the gene for apolipo-protein E on chromosome 19
    Clin Genet, 26 (5), 389-96
    PubMed 6094053
  2. Magnus P, Børresen AL, Opstad PK, Bugge JF, Berg K (1984)
    Increase in the ratio of serum levels of apolipoproteins A-I and A-II during prolonged physical strain and calorie deficiency
    Eur J Appl Physiol Occup Physiol, 53 (1), 21-4
    PubMed 6439559
  3. Marhaug G, Børresen AL, Husby G, Nordstoga K (1984)
    A comparative study of serum amyloid a protein (SAA) from mink and man
    Comp Biochem Physiol B, 78 (2), 401-6
    PubMed 6467904
  4. Tsipouras P, Børresen AL, Dickson LA, Berg K, Prockop DJ, Ramirez F (1984)
    Molecular heterogeneity in the mild autosomal dominant forms of osteogenesis imperfecta
    Am J Hum Genet, 36 (6), 1172-9
    PubMed 6097110
  5. Ziesler O, Hole K, Haugan I, Børresen AL, Gjessing LR, Sjaastad O (1984)
    Transport and distribution of homocarnosine after intracerebroventricular and intravenous injection in the rat
    Neurochem Res, 9 (5), 637-48
    PubMed 6472567

Publications 1982

  1. Børresen AL, Maartmann-Moe K, Berg K (1982)
    Serum reserve cholesterol binding capacity (SRCBC) in familial hypercholesterolemia
    Clin Genet, 21 (6), 362-5
    PubMed 6813000
  2. Fowler B, Børresen AL, Boman N (1982)
    Prenatal diagnosis of homocystinuria
    Lancet, 2 (8303), 875
    PubMed 6126732

Publications 1981

  1. Berg K, Børresen AL, Nance WE (1981)
    Apparent influence of marker genotypes on variation in serum cholesterol in monozygotic twins
    Clin Genet, 19 (1), 67-70
    PubMed 6936104
  2. Børresen AL, Berg K (1981)
    Serum reserve cholesterol binding capacity (SRCBC): the relative importance of different lipoprotein classes
    Artery, 9 (2), 96-119
    PubMed 6794547
  3. Børresen AL, Berg K (1981)
    The apoE polymorphism studied by two-dimensional, high-resolution gel electrophoresis of serum
    Clin Genet, 20 (6), 438-48
    PubMed 7199983
  4. Børresen AL, Berg K, Dahlén G, Gillnäs T, Ericson C (1981)
    The effect of Gemfibrozil on human serum apolipoproteins and on serum reserve cholesterol binding capacity (SRCBC)
    Artery, 9 (1), 77-86
    PubMed 7018466
  5. Børresen AL, Berg K, Magnus P (1981)
    A twin study of aryl hydrocarbon hydroxylase (AHH) inducibility in cultured lymphocytes
    Clin Genet, 19 (4), 281-9
    PubMed 6944164
  6. Maartmann-Moe K, Magnus P, Børresen AL, Berg K (1981)
    Low density lipoprotein receptor activity in cultured fibroblasts from subjects with or without ischemic heart disease (in the absence of familial hypercholesterolemia)
    Clin Genet, 20 (5), 337-46
    PubMed 6277536

Publications 1980

  1. Børresen AL, Berg K (1980)
    Presence of "free" apoA-I in serum: implications for immunological quantification of HDL and its apoproteins
    Artery, 7 (2), 139-60
    PubMed 7425861
  2. Dahlén G, Gillnäs T, Børresen AL, Berg K, Ericson C (1980)
    Effect of gemfibrozil on serum lipid levels
    Artery, 7 (3), 224-31
    PubMed 7008748
  3. Muggerud A, Reine E (1980)
    [Child abuse]
    Sykepleien, 67 (10), 16-21, 24
    PubMed 6901301
  4. Skogen B, Natvig JB, Bøorresen AL, Berg K (1980)
    Degradation of amyloid-related serum protein SAA by a component present in rabbit and human serum
    Scand J Immunol, 11 (6), 643-8
    PubMed 6777866

Publications 1979

  1. Berg K, Börresen AL, Dahlen G (1979)
    Effect of smoking on serum levels of HDL apoproteins
    Atherosclerosis, 34 (3), 339-43
    PubMed 229876
  2. Berg K, Dahlén G, Børresen AL (1979)
    Lp(a) phenotypes, other lipoprotein parameters, and a family history of coronary heart disease in middle-aged males
    Clin Genet, 16 (5), 347-52
    PubMed 230000
  3. Skogen B, Børresen AL, Natvig JB, Berg K, Michaelsen TE (1979)
    High-density lipoprotein as carrier for amyloid-related protein SAA in rabbit serum
    Scand J Immunol, 10 (1), 39-45
    PubMed 224449

Publications 1978

  1. Børresen AL (1978)
    The distribution of the inherited Hl 1 and R 67 antigens on rabbit serum high density lipoprotein (HDL) particles
    J Immunogenet, 5 (1), 13-23
    PubMed 205613
  2. Børresen AL, Kindt TJ (1978)
    Purification and partial characterization of the apoA-I of rabbit high density lipoprotein
    J Immunogenet, 5 (1), 5-12
    PubMed 205614
  3. Børresen AL, Kindt TJ, Berg K (1978)
    Partial purification and characterization of the inherited Hl 1 and R 67 antigens of rabbit serum high density lipoprotein
    J Immunogenet, 5 (2), 71-86
    PubMed 207781

Publications 1977

  1. Borresen AL (1977)
    High densitiy lipoprotein (HDL) polymorphisms in rabbit: production of antibody to rabbit allotype (R 67) in sheep
    J Immunogenet, 4 (3), 149-58
    PubMed 197172
  2. Borresen AL, Berg K, Kindt TJ (1977)
    A linkage study of rabbit serum high density lipoprotein (HDL) allotypes
    J Immunogenet, 4 (2), 81-95
    PubMed 194985

Publications 1976

  1. Berg K, Borresen AL (1976)
    Serum-high-density-lipoprotein and atherosclerotic heart-disease
    Lancet, 1 (7958), 499-501
    PubMed 55778
  2. Berg K, Borresen AL, Frick MH, Dahlén G, Stene J (1976)
    Letter: Serum-H.D.L. in a therosclerotic heart-disease
    Lancet, 2 (7975), 40-1
    PubMed 59096
  3. Borresen AL (1976)
    High density lipoprotein (HDL) polymorphisms in rabbit. III. Quantitative determination of HDL and the inherited Hl 1 and R 67 antigens
    J Immunogenet, 3 (2), 91-103
    PubMed 58950
  4. Borresen AL (1976)
    High density lipoprotein (HDL) polymorphisms in rabbit. I. A comparative study of rabbit and human serum high density lipoprotein
    J Immunogenet, 3 (2), 73-81
    PubMed 180184
  5. Borresen AL (1976)
    High density lipoprotein (HDL) polymorphisms in rabbit. II. A study of the inherited Hl 1 and R 67 antigens in relation to HDL polypeptides
    J Immunogenet, 3 (2), 83-9
    PubMed 58949
  6. Borresen AL (1976)
    Letter: Prenatal metachromatic leukodystrophy
    Helv Paediatr Acta, 30 (6), 553
    PubMed 1270328

Publications 1973

  1. Borresen AL, van der Hagen CB (1973)
    Metachromatic leukodystrophy. II. Direct determination of arylsulphatase A activity in amniotic fluid
    Clin Genet, 4 (5), 442-6
    PubMed 4751314
  2. van der Hagen CB, Borresen AL, Molne K, Oftedal G, Bjoro K, Berg K (1973)
    Metachromatic leukodystrophy. I. Prenatal detection of arylsulphatase A deficiency
    Clin Genet, 4 (3), 256-9
    PubMed 4765208

Publications 1972

  1. Torsvik H, Børresen A, Berg K, Boman H (1972)
    Preliminary assignment of the inherited Hl 1 antigen to the apoA-I polypeptide of rabbit high density lipoprotein
    FEBS Lett, 28 (2), 153-155
    PubMed 11946845