Odd Terje Brustugun
Position: Project group leader, assoc. prof., MD, Ph.D.
Phone: +47 22 78 14 87
Email:

Publications by Odd Terje Brustugun

36 publications found

Publications in press

  1. Brustugun OT, Helland A
    Rapid reduction in the incidence of cancer of unknown primary. A population-based study
    Acta Oncol (in press)
    PubMed 23550957

Publications 2013

  1. Nordgård O, Singh G, Solberg S, Jørgensen L, Halvorsen AR, Smaaland R, Brustugun OT, Helland A (2013)
    Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
    PLoS One, 8 (5), e62153
    PubMed 23671585

Publications 2012

  1. Brustugun OT, Helland Å, Fjellbirkeland L, Kleinberg L, Ariansen S, Jebsen P, Scott H, Dønnem T, Bremnes R, Berg T, Grønberg BH, Dai HY, Wahl SG, Mangseth K, Helgeland L (2012)
    [Mutation testing for non-small-cell lung cancer]
    Tidsskr Nor Laegeforen, 132 (8), 952-5
    PubMed 22562326
  2. Helland Å, Solberg S, Brustugun OT (2012)
    Incidence and survival of malignant pleural mesothelioma in norway: a population-based study of 1686 cases
    J Thorac Oncol, 7 (12), 1858-61
    PubMed 23154557
  3. Lund-Iversen M, Kleinberg L, Fjellbirkeland L, Helland Å, Brustugun OT (2012)
    Clinicopathological characteristics of 11 NSCLC patients with EGFR-exon 20 mutations
    J Thorac Oncol, 7 (9), 1471-3
    PubMed 22895145
  4. Nordlund MS, Stieber P, Brustugun OT, Warren DJ, Paus E (2012)
    Characteristics and clinical validity of two immunoassays for ProGRP
    Tumour Biol, 33 (4), 1105-13
    PubMed 22399443
  5. Peifer M, Fernández-Cuesta L, Sos ML, George J, Seidel D, Kasper LH, Plenker D, Leenders F, Sun R, Zander T, Menon R, Koker M, Dahmen I, Müller C, Di Cerbo V, Schildhaus HU, Altmüller J, Baessmann I, Becker C, de Wilde B, Vandesompele J, Böhm D, Ansén S, Gabler F, Wilkening I et al. (2012)
    Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer
    Nat Genet, 44 (10), 1104-10
    PubMed 22941188
  6. Rud AK, Lund-Iversen M, Berge G, Brustugun OT, Solberg SK, Mælandsmo GM, Boye K (2012)
    Expression of S100A4, ephrin-A1 and osteopontin in non-small cell lung cancer
    BMC Cancer, 12, 333
    PubMed 22853000
  7. Sagerup CM, Småstuen M, Johannesen TB, Helland A, Brustugun OT (2012)
    Increasing age and carcinoma not otherwise specified: a 20-year population study of 40,118 lung cancer patients
    J Thorac Oncol, 7 (1), 57-63
    PubMed 21900838
  8. Waldeland E, Brustugun OT, Ramberg C, Helland Å (2012)
    [Stereotactic irradiation in spinal metastases]
    Tidsskr Nor Laegeforen, 132 (22), 2478-9
    PubMed 23338027
  9. Waldeland E, Ramberg C, Arnesen MR, Helland A, Brustugun OT, Malinen E (2012)
    Dosimetric impact of a frame-based strategy in stereotactic radiotherapy of lung tumors
    Acta Oncol, 51 (5), 603-9
    PubMed 22304490

Publications 2011

  1. Berg A, Brustugun OT, Lund-Iversen M, Helland Å (2011)
    Palmar bullous blistering induced by erlotinib
    J Thorac Oncol, 6 (5), 954
    PubMed 21623268
  2. Hammerman PS, Sos ML, Ramos AH, Xu C, Dutt A, Zhou W, Brace LE, Woods BA, Lin W, Zhang J, Deng X, Lim SM, Heynck S, Peifer M, Simard JR, Lawrence MS, Onofrio RC, Salvesen HB, Seidel D, Zander T, Heuckmann JM, Soltermann A, Moch H, Koker M, Leenders F et al. (2011)
    Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer
    Cancer Discov, 1 (1), 78-89
    PubMed 22328973
  3. Helland Å, Skaug HM, Kleinberg L, Iversen ML, Rud AK, Fleischer T, Sagerup C, Solberg S, Jørgensen L, Ariansen S, Brustugun OT (2011)
    EGFR gene alterations in a Norwegian cohort of lung cancer patients selected for surgery
    J Thorac Oncol, 6 (5), 947-50
    PubMed 21623266
  4. Knudtsen IS, Rødal J, Brustugun OT, Helland Å, Skretting A, Malinen E (2011)
    Dynamic respiratory gated (18)FDG-PET of lung tumors - a feasibility study
    Acta Oncol, 50 (6), 889-96
    PubMed 21767189
  5. Sagerup CM, Småstuen M, Johannesen TB, Helland Å, Brustugun OT (2011)
    Sex-specific trends in lung cancer incidence and survival: a population study of 40,118 cases
    Thorax, 66 (4), 301-7
    PubMed 21199818
  6. Turzer M, Brustugun OT, Waldeland E, Helland A (2011)
    Stereotactic body radiation therapy is effective and safe in patients with early-stage non-small cell lung cancer with low performance status and severe comorbidity
    Case Rep Oncol, 4 (1), 25-34
    PubMed 21526003

Publications 2010

  1. Courter D, Cao H, Kwok S, Kong C, Banh A, Kuo P, Bouley DM, Vice C, Brustugun OT, Denko NC, Koong AC, Giaccia A, Le QT (2010)
    The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways
    PLoS One, 5 (3), e9633
    PubMed 20224789
  2. Turzer M, Brustugun OT, Helland A (2010)
    Excessive Soft Tissue Reaction after Stereotactic Body Radiation Therapy in a Woman with Four Different Cancer Diagnoses
    Case Rep Oncol, 3 (2), 195-201
    PubMed 20740196
  3. Weiss J, Sos ML, Seidel D, Peifer M, Zander T, Heuckmann JM, Ullrich RT, Menon R, Maier S, Soltermann A, Moch H, Wagener P, Fischer F, Heynck S, Koker M, Schöttle J, Leenders F, Gabler F, Dabow I, Querings S, Heukamp LC, Balke-Want H, Ansén S, Rauh D, Baessmann I et al. (2010)
    Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer
    Sci Transl Med, 2 (62), 62ra93
    PubMed 21160078

Publications 2009

  1. Helland A, Brustugun OT (2009)
    [Lung cancer in smokers and never-smokers]
    Tidsskr Nor Laegeforen, 129 (18), 1859-62
    PubMed 19844277
  2. Sagerup CM, Brustugun OT, Jørgensen L (2009)
    [A 67-year old man with right arm paresthesias]
    Tidsskr Nor Laegeforen, 129 (24), 2613-5
    PubMed 20029558

Publications 2008

  1. Fredriksson S, Horecka J, Brustugun OT, Schlingemann J, Koong AC, Tibshirani R, Davis RW (2008)
    Multiplexed proximity ligation assays to profile putative plasma biomarkers relevant to pancreatic and ovarian cancer
    Clin Chem, 54 (3), 582-9
    PubMed 18171715
  2. Lyng H, Lando M, Brøvig RS, Svendsrud DH, Johansen M, Galteland E, Brustugun OT, Meza-Zepeda LA, Myklebost O, Kristensen GB, Hovig E, Stokke T (2008)
    GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data
    Genome Biol, 9 (5), R86
    PubMed 18500990

Publications 2005

  1. Brustugun OT, Reed W, Poulsen JP, Bruland OS (2005)
    Primary osteosarcoma of the breast
    Acta Oncol, 44 (7), 767-70
    PubMed 16227171

Publications 2004

  1. Lyng H, Beigi M, Svendsrud DH, Brustugun OT, Stokke T, Kristensen GB, Sundfør K, Skjønsberg A, De Angelis PM (2004)
    Intratumor chromosomal heterogeneity in advanced carcinomas of the uterine cervix
    Int J Cancer, 111 (3), 358-66
    PubMed 15221962

Publications 2003

  1. Brustugun OT, Nome O, Bruland S ØS, Ottestad L, Lilleby W (2003)
    [Breast cancer patients' assessment of waiting time before radiotherapy]
    Tidsskr Nor Laegeforen, 123 (12), 1685-6
    PubMed 12821991
  2. Tronstad KJ, Gjertsen BT, Krakstad C, Berge K, Brustugun OT, Døskeland SO, Berge RK (2003)
    Mitochondrial-targeted fatty acid analog induces apoptosis with selective loss of mitochondrial glutathione in promyelocytic leukemia cells
    Chem Biol, 10 (7), 609-18
    PubMed 12890534

Publications 2002

  1. Fladmark KE, Brustugun OT, Mellgren G, Krakstad C, Boe R, Vintermyr OK, Schulman H, Doskeland SO (2002)
    Ca2+/calmodulin-dependent protein kinase II is required for microcystin-induced apoptosis
    J Biol Chem, 277 (4), 2804-11
    PubMed 11713251

Publications 2000

  1. Schwede F, Brustugun OT, Zorn-Kruppa M, Døskeland SO, Jastorff B (2000)
    Membrane-permeant, bioactivatable analogues of cGMP as inducers of cell death in IPC-81 leukemia cells
    Bioorg Med Chem Lett, 10 (6), 571-3
    PubMed 10741556

Publications 1999

  1. Fladmark KE, Brustugun OT, Hovland R, Boe R, Gjertsen BT, Zhivotovsky B, Døskeland SO (1999)
    Ultrarapid caspase-3 dependent apoptosis induction by serine/threonine phosphatase inhibitors
    Cell Death Differ, 6 (11), 1099-108
    PubMed 10578179

Publications 1998

  1. Brustugun OT, Fladmark KE, Doskeland SO, Orrenius S, Zhivotovsky B (1998)
    Apoptosis induced by microinjection of cytochrome c is caspase-dependent and is inhibited by Bcl-2
    Cell Death Differ, 5 (8), 660-8
    PubMed 10200521
  2. Zhivotovsky B, Orrenius S, Brustugun OT, Døskeland SO (1998)
    Injected cytochrome c induces apoptosis
    Nature, 391 (6666), 449-50
    PubMed 9461210

Publications 1995

  1. Bruserud O, Tore Gjertsen B, Brustugun OT, Bassøe CF, Nesthus I, Espen Akselsen P, Bühring HJ, Pawelec G (1995)
    Effects of interleukin 10 on blast cells derived from patients with acute myelogenous leukemia
    Leukemia, 9 (11), 1910-20
    PubMed 7475283
  2. Brustugun OT, Mellgren G, Gjertsen BT, Bjerkvig R, Døskeland SO (1995)
    Sensitive and rapid detection of beta-galactosidase expression in intact cells by microinjection of fluorescent substrate
    Exp Cell Res, 219 (2), 372-8
    PubMed 7641787
  3. Vintermyr OK, Bøe R, Brustugun OT, Maronde E, Aakvaag A, Døskeland SO (1995)
    Cyclic adenosine monophosphate (cAMP) analogs 8-Cl- and 8-NH2-cAMP induce cell death independently of cAMP kinase-mediated inhibition of the G1/S transition in mammary carcinoma cells (MCF-7)
    Endocrinology, 136 (6), 2513-20
    PubMed 7750473