
| Åslaug Helland | |
| Position: | Assoc. prof., MD |
| Phone: | +47 22 78 14 85/13 38 74 |
| Email: | |
Education
- MD, University of Oslo
- PhD, Dept of Genetics, The Norwegian Radium Hospital, Oslo, 2000.
“Malignancy of the cervix uteri – genetic susceptibility and somatic DNA alterations in tumor in relation to prognosis” - Postdoc at Stanford University, 2003-2004
- Physician, Dept of Oncology, The Norwegian Radium Hospital 2001-2003, 2004-
- Postdoc, Dept of Genetics, The Norwegian Radium Hospital, 2001-2003, 2004 –
Research
Molecular Studies of Ovarian Carcinoma
Mammographic Density and Genomics
Radiation and breast cancer
HER2 positive tumours
Molecular mechanisms involved in the radiation response of patients with cervical carcinoma
Publications in press
Rapid reduction in the incidence of cancer of unknown primary. A population-based study
Acta Oncol (in press)
PubMed 23550957
Publications 2013
High levels of genomic aberrations in serous ovarian cancers are associated with better survival
PLoS One, 8 (1), e54356
PubMed 23372714
Novel molecular tumor cell markers in regional lymph nodes and blood samples from patients undergoing surgery for non-small cell lung cancer
PLoS One, 8 (5), e62153
PubMed 23671585
Publications 2012
[Mutation testing for non-small-cell lung cancer]
Tidsskr Nor Laegeforen, 132 (8), 952-5
PubMed 22562326
Incidence and survival of malignant pleural mesothelioma in norway: a population-based study of 1686 cases
J Thorac Oncol, 7 (12), 1858-61
PubMed 23154557
Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling
Proc Natl Acad Sci U S A, 109 (8), 2802-7
PubMed 21908711
Clinicopathological characteristics of 11 NSCLC patients with EGFR-exon 20 mutations
J Thorac Oncol, 7 (9), 1471-3
PubMed 22895145
Increasing age and carcinoma not otherwise specified: a 20-year population study of 40,118 lung cancer patients
J Thorac Oncol, 7 (1), 57-63
PubMed 21900838
[Stereotactic irradiation in spinal metastases]
Tidsskr Nor Laegeforen, 132 (22), 2478-9
PubMed 23338027
Dosimetric impact of a frame-based strategy in stereotactic radiotherapy of lung tumors
Acta Oncol, 51 (5), 603-9
PubMed 22304490
Publications 2011
Palmar bullous blistering induced by erlotinib
J Thorac Oncol, 6 (5), 954
PubMed 21623268
Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer
Cancer Discov, 1 (1), 78-89
PubMed 22328973
Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers
PLoS One, 6 (4), e18064
PubMed 21533284
EGFR gene alterations in a Norwegian cohort of lung cancer patients selected for surgery
J Thorac Oncol, 6 (5), 947-50
PubMed 21623266
Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas
BMC Cancer, 11, 332
PubMed 21812955
Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features
BMC Med Genomics, 4, 77
PubMed 22044755
Dynamic respiratory gated (18)FDG-PET of lung tumors - a feasibility study
Acta Oncol, 50 (6), 889-96
PubMed 21767189
Sex-specific trends in lung cancer incidence and survival: a population study of 40,118 cases
Thorax, 66 (4), 301-7
PubMed 21199818
Stereotactic body radiation therapy is effective and safe in patients with early-stage non-small cell lung cancer with low performance status and severe comorbidity
Case Rep Oncol, 4 (1), 25-34
PubMed 21526003
Publications 2010
Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density
Breast Cancer Res, 12 (4), R65
PubMed 20799965
[How do Norwegian oncologists perceive their working conditions?]
Tidsskr Nor Laegeforen, 130 (5), 487-9
PubMed 20224615
Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression
Mol Oncol, 4 (2), 98-118
PubMed 20060370
Excessive Soft Tissue Reaction after Stereotactic Body Radiation Therapy in a Woman with Four Different Cancer Diagnoses
Case Rep Oncol, 3 (2), 195-201
PubMed 20740196
Publications 2009
[Lung cancer in smokers and never-smokers]
Tidsskr Nor Laegeforen, 129 (18), 1859-62
PubMed 19844277
Methylation detection oligonucleotide microarray analysis: a high-resolution method for detection of CpG island methylation
Nucleic Acids Res, 37 (12), e89
PubMed 19474344
TP53 codon 72 polymorphism and cervical cancer: a pooled analysis of individual data from 49 studies
Lancet Oncol, 10 (8), 772-84
PubMed 19625214
Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis
PLoS One, 4 (5), e5583
PubMed 19440550
Publications 2008
[The selected contagions]
Tidsskr Nor Laegeforen, 128 (20), 2304
PubMed 19096483
Publications 2007
Germline glutathione S-transferase variants in breast cancer: relation to diagnosis and cutaneous long-term adverse effects after two fractionation patterns of radiotherapy
Int J Radiat Oncol Biol Phys, 67 (4), 1163-71
PubMed 17336217
Publications 2006
Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers
PLoS Med, 3 (3), e47
PubMed 16417408
Radiation-induced effects on gene expression: an in vivo study on breast cancer
Radiother Oncol, 80 (2), 230-5
PubMed 16890317
Publications 2005
PIK3CA mutations in advanced ovarian carcinomas
Hum Mutat, 25 (3), 322
PubMed 15712344
Protein expression and prognostic value of genes in the erb-b signaling pathway in advanced ovarian carcinomas
Am J Clin Pathol, 124 (3), 392-401
PubMed 16191507
Publications 2004
TP53 mutations in early-stage ovarian carcinoma, relation to long-term survival
Br J Cancer, 90 (3), 678-85
PubMed 14760384
Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma
Hum Mutat, 24 (1), 21-34
PubMed 15221786
Publications 2003
X chromosome inactivation in cervical cancer patients
Cancer Genet Cytogenet, 146 (1), 73-6
PubMed 14499700




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