Anne-Lise Børresen-Dale
Position: Professor, Head of Dept.
Phone: +47 22 78 13 74
Email:
 

Mini CV


Academic Degrees.

  • 1970 M.S. Biochemistry, Technical University of Norway, Trondheim, Norway.
  • 1978 Doctor of Science in Medical Biochemical Genetics, University of Oslo, Norway.
  • 1987 Judged qualified as a professor in gene technology, University of Oslo, Norway.
  • 1992 Professor in Molecular Tumorbiology, Univ. of Oslo, Norway (still holding)
  • 2000 Professor in Molecular Oncology, Univ. of Bergen, Norway (still holding)
Positions held
  • 1970-72 Research assistant, Institute of Medical Genetics, University of Oslo.
  • 1972-78 Research Fellow, Institute of Medical Genetics, University of Oslo.
  • 1978-82 Senior Research Fellow, Institute of Medical Genetics, University of Oslo
  • 1982-86 Senior Biochemist, head of biochemical section for prenatal diagnosis, Department of Genetics, UiO.
  • 1987-99 Senior Scientist, Dept. of Genetics, Inst. for Cancer Research, DNR, Norway
  • 1993-99 Head of DNA Diagnostic Service Lab, DNR, Oslo, Norway.
  • 1999-dd Head of Department, Dept. Genetics, Inst. for Cancer Research, DNR, Norway.
Honors and awards.
  • 1989 Prof. Olav Torgersens Prize and Memorial Lecture, Title: Gene technology in the fight against cancer.
  • 1989 Honorary lecturer at the 175th anniversary of the Medical Faculty, Univ. of Oslo.
    Title: Genes, inheritance and cancer; gene technology in cancer diagnosis and prevention.
  • 1994 King Olav V's Cancer Research Prize
  • 1998 Elected member of: “Det Kongelige Norske Videnskabers Selskab”
  • 2001 Honorary member of The Norwegian Biochemical Society
  • 2002 University of Oslo’s Research Prize for Outstanding Research
  • 2002 Salhus Ansvar Medical prize for Outstanding Research in Tumorbiology
  • 2002 The Employer of the year at The Norwegian Raduimhospital
Studies in foreign laboratories
From 1972 to 2002 I have worked from 1-4 months as a Visiting scientist in different laboratories in US and Europe. These are: 1) Dep. Hum.Biol.Chem& Gen, Univ. Texas, (1972, Barbara Bowman), protein sequencing. 2) The Rockefeller University, New York (1977, Thomas Kindt), protein sequencing, 3) EMBL (1985, Hans Lerach), studying recombinant DNA techniques, 4) Recombinant DNA Tech. Lab, Helsinki, Finland (1986, Leena Peltonen), 5) Harvard Med. Sch., Mass. (1990, David Yandell), PCR/SSCP on Rb, 6) MIT, Cent. Envir. Health Sci. MA (1992, William Thilly), mutation assay systems, 7) MGH Cancer C. and Harvard Med. Sch, Boston, MA (1992, Stephen Friend) cloning strategies with relevance to Ataxia Telangiectasia and TP53. 8) Four months sabbatical as Visiting Professor, spring 2002 at Dept of Genetics, Stanford University, CA (David Botstein), Microarray analyses.

Administrative Experience
No formal education in leadership, but have followed courses in "Group leader management" arranged by UiO and DNR. Have had several positions where strategic planning was needed. Head of the DNA section at the Department of Genetic since 1987 and have built up a research group consisting of 24 persons. In 1999 I became the Chairman of the Department of Genetics with the administrative and scientific responsibility for at present 36 employers. Took the initiative to start a DNA diagnostic lab at the Department of Pathology and was up to 1/1-99 in charge of the Molecular Biology section of this lab.
Have initiated many scientific projects with both national and international collaborations as well as several international meetings and courses and have been chairman of several of them. Elected to many committees and have also chaired and are still chairing several. In 1989 I took the initiative to start a Nordic technology development project partly financed by Nordisk Industrifond (Total cost of the project was 10.2 mill NKr.). Was the principal investigator in this project for three years with participating groups in Sweden, Finland, Denmark and Iceland. In this project the mutation analyses system (CDGE) was developed in my lab, and was explored in the different collaborating groups, which all had different applications for the technology. The project also had industrial partners, and resulted in the collaboration with BIORAD and the development of the commercial system DGENE/DCODE that is now sold worldwide.
Have been on the steering Committee of the European Breast Cancer Linkage consortium for 6 years. This Consortium has had EU grants for two three year-periods, ending 1/1-99. Many publications have come from this collaboration. The network established is still working and many further collaborative projects are still ongoing. Took the initiative to start planning for a new EU-grant in the 6th framework on radiation exposure and breast cancer risk this fall. Are one of the PI`s in the large multicenter study WECARE financed by NCI/NIH.
A new EU Integrated project on “Mutant TP53 and and Cancer” has been ranked as no. 1 of 116 in the Cancer aerea with funding from 2004. I am one of the 16 partners in this project with the aim of doing tumor analyses.
Member of The Norwegian Radiumhospital`s Scientific Board "Forskningutvalget" since 1996, where new projects are evaluated and strategic planning for the Hospital is performed. Served as first deputy member of the "Akademiske Kollegium" at the University of Oslo for 3 years since 1999.
In 1987 I was one of the founders of a small Biotech company, Med Probe AS. Served as a Director for research and development for several years, and are still a board member. The company employs today 12 persons and had total revenue in 2003 of approxim. 35 mill NKr.

Have been on the evaluation committee for 9 professorships (3 international) and 21 doctoral thesises (4 international) in addition to reviewing several international grant applications. Have also served on a number of other committees, both national and international, the most important are listed below:

National:
1986-91 Secretary General, The Norwegian Biochemical Society.
1988 95 Board Member of the Research Council of The Norwegian Cancer Society.
1987 94 Council Member of The Norwegian Research Council for Science and Humanities.
1990 95 Vice chairman of the Board of DNR and Institute for Cancer Research.
1993-99 Board member of the Steering com. of the Concerted Action on Hereditary Breast Cancer.
1995-00 Chairman of expert committee on Biotech. And Genetics. Norwegian Board of Health.
1995-00 Chairman of the program committee, MedKap NFR
1999- 01 First deputy member of the Academic Collegium UiO
2000-01 Member of a deliberation committee for commercialization from academia, Ministry of education and
Research affairs, KUF (Bernt utvalget ).
2001- Board member of the National Committee for Functional Genomics, FUGE

International
1992-93 Member of Discipline Oriented Group (DOG) Commission of the European Committee. (EU)
1996-98 Member of Fellowship Selection Committee, International Agency for research of Cancer, IACR, Lyon.
1999- Member of the Scientific Council, International Agency for Research of Cancer, IARC, Lyon
2002- Vice Chairman of the Scientific Council, IACR, Lyon
2000- Member of International Affairs Committee, American Association for Cancer Research, AACR
2001 Member of the Pezcoller Prize Committee, AACR/Italian Cancer Society
2002 Member of the Selection Committee for the Women in Cancer Research Award, AACR
2002 Site Visiting and Evaluation Committee for Cancer Research UK to Cambridge Cancer Center, UK
2002 Chairperson of a subcommittee of the 2003 AACR Program Committee
2003- Member of The Board of Directors, American Association for Cancer Research (AACR)

Editorial boards:
Pharmacogenetics (to 1999), British Journal of Cancer (to 2000), Human Mutation (corresponding editor), Biotechniques, Breast Cancer Research, Journal of the Norwegian Medical Association, Molecular Cancer Research, Public Library of Science (PloS).

Teaching responsibilities and course organization
Formal pedagogical education from UiO, a basic course in University Pedagogic in 1976 and one advances course in 1983. Since 1975 lecturer for medical students in biochemical genetics and gene technology and lecturer for science students in molecular genetics at UiO, both at undergraduate and graduate level. Since 1997 a PBL (problem based learning) teacher for medical students in cell biology and genetics.
I have been the main supervisor of 16 PhD degrees (12 completed) and 12 undergraduates (10 completed).
Since 1997 I have been on the organizing committees of more than 20 different meetings and symposia, both national and international. The most important, where I also was the chairman is listed below:
1992 : Chairman and organizer: EMBO Adv. Course on: "Detection of base mutation in the human genome".
1995 and 2000: Chairman and organizer; 1st and 2nd International Symposium on the Molecular Biology of
Breast Cancer.

Current Research Projects
Molecular genetic studies of breast and ovarian cancer. Identification of genotypes and gene expression profiles
contributing to elevated cancer risk, radiation sensitivity, tumour aggressiveness and therapy resistance.

Publications:
Author of 250 scientific papers in international reviewed journals, 20 chapters/reviews, 31
Nordic or popular scientific articles.
 

Author network for Anne-Lise Børresen-Dale by COREMINE medical


Publications in press

Ghoussaini M, Fletcher O, Michailidou K, Turnbull C, Schmidt MK, Dicks E, Dennis J, Wang Q, Humphreys MK, Luccarini C, Baynes C, Conroy D, Maranian M, Ahmed S, Driver K, Johnson N, Orr N, Dos Santos Silva I, Waisfisz Q, Meijers-Heijboer H, Uitterlinden AG, Rivadeneira F, Netherlands Collaborative Group on Hereditary Breast and Ovarian Cancer (HEBON), Hall P, Czene K et al.
Genome-wide association analysis identifies three new breast cancer susceptibility loci
Nat Genet (in press)
PubMed 22267197

Kaveh F, Edvardsen H, Borresen-Dale AL, Kristensen VN, Solvang HK
Allele-specific disparity in breast cancer
BMC Med Genomics, 4 (1), 85 (in press)
PubMed 22188678

Kristensen VN, Vaske CJ, Ursini-Siegel J, Van Loo P, Nordgard SH, Sachidanandam R, Sørlie T, Wärnberg F, Haakensen VD, Helland A, Naume B, Perou CM, Haussler D, Troyanskaya OG, Børresen-Dale AL
Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling
Proc Natl Acad Sci U S A (in press)
PubMed 21908711

Mathiesen RR, Fjelldal R, Liestøl K, Due EU, Geigl JB, Riethdorf S, Borgen E, Rye IH, Schneider IJ, Obenauf AC, Mauermann O, Nilsen G, Christian Lingjaerde O, Børresen-Dale AL, Pantel K, Speicher MR, Naume B, Baumbusch LO
High-resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer
Int J Cancer (in press)
PubMed 21935921

Weigman VJ, Chao HH, Shabalin AA, He X, Parker JS, Nordgard SH, Grushko T, Huo D, Nwachukwu C, Nobel A, Kristensen VN, Børresen-Dale AL, Olopade OI, Perou CM
Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival
Breast Cancer Res Treat (in press)
PubMed 22048815

Publications 2012

Freed-Pastor WA, Mizuno H, Zhao X, Langerød A, Moon SH, Rodriguez-Barrueco R, Barsotti A, Chicas A, Li W, Polotskaia A, Bissell MJ, Osborne TF, Tian B, Lowe SW, Silva JM, Børresen-Dale AL, Levine AJ, Bargonetti J, Prives C (2012)
Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway
Cell, 148 (1-2), 244-58
PubMed 22265415

Van Loo P, Nilsen G, Nordgard SH, Vollan HK, Børresen-Dale AL, Kristensen VN, Lingjærde OC (2012)
Analyzing cancer samples with SNP arrays
Methods Mol Biol, 802, 57-72
PubMed 22130873

Publications 2011

Akslen LA, Straume O, Geisler S, Sørlie T, Chi JT, Aas T, Børresen-Dale AL, Lønning PE (2011)
Glomeruloid microvascular proliferation is associated with lack of response to chemotherapy in breast cancer
Br J Cancer, 105 (1), 9-12
PubMed 21673677

Borgan E, Navon R, Vollan HK, Schlichting E, Sauer T, Yakhini Z, Lingjærde OC, Sørlie T, Børresen-Dale AL (2011)
Ischemia caused by time to freezing induces systematic microRNA and mRNA responses in cancer tissue
Mol Oncol, 5 (6), 564-76
PubMed 21917534

Borge KS, Børresen-Dale AL, Lingaas F (2011)
Identification of genetic variation in 11 candidate genes of canine mammary tumour
Vet Comp Oncol, 9 (4), 241-50
PubMed 22077404

Broeks A, Schmidt MK, Sherman ME, Couch FJ, Hopper JL, Dite GS, Apicella C, Smith LD, Hammet F, Southey MC, Van 't Veer LJ, de Groot R, Smit VT, Fasching PA, Beckmann MW, Jud S, Ekici AB, Hartmann A, Hein A, Schulz-Wendtland R, Burwinkel B, Marme F, Schneeweiss A, Sinn HP, Sohn C et al. (2011)
Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium
Hum Mol Genet, 20 (16), 3289-303
PubMed 21596841

Edgren H, Murumagi A, Kangaspeska S, Nicorici D, Hongisto V, Kleivi K, Rye IH, Nyberg S, Wolf M, Borresen-Dale AL, Kallioniemi O (2011)
Identification of fusion genes in breast cancer by paired-end RNA-sequencing
Genome Biol, 12 (1), R6
PubMed 21247443

Enerly E, Steinfeld I, Kleivi K, Leivonen SK, Aure MR, Russnes HG, Rønneberg JA, Johnsen H, Navon R, Rødland E, Mäkelä R, Naume B, Perälä M, Kallioniemi O, Kristensen VN, Yakhini Z, Børresen-Dale AL (2011)
miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors
PLoS One, 6 (2), e16915
PubMed 21364938

Gonzalez-Angulo AM, Hennessy BT, Meric-Bernstam F, Sahin A, Liu W, Ju Z, Carey MS, Myhre S, Speers C, Deng L, Broaddus R, Lluch A, Aparicio S, Brown P, Pusztai L, Symmans WF, Alsner J, Overgaard J, Borresen-Dale AL, Hortobagyi GN, Coombes KR, Mills GB (2011)
Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer
Clin Proteomics, 8 (1), 11
PubMed 21906370

Helland Å, Anglesio MS, George J, Cowin PA, Johnstone CN, House CM, Sheppard KE, Etemadmoghadam D, Melnyk N, Rustgi AK, Phillips WA, Johnsen H, Holm R, Kristensen GB, Birrer MJ, Australian Ovarian Cancer Study Group, Pearson RB, Børresen-Dale AL, Huntsman DG, deFazio A, Creighton CJ, Smyth GK, Bowtell DD (2011)
Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers
PLoS One, 6 (4), e18064
PubMed 21533284

Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, Wang Y, Kong B, Langerød A, Børresen-Dale AL, Kim SK, van de Vijver M, Sukumar S, Whitfield ML, Kellis M, Xiong Y, Wong DJ, Chang HY (2011)
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
Nat Genet, 43 (7), 621-9
PubMed 21642992

Haakensen VD, Bjøro T, Lüders T, Riis M, Bukholm IK, Kristensen VN, Troester MA, Homen MM, Ursin G, Børresen-Dale AL, Helland Å (2011)
Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas
BMC Cancer, 11, 332
PubMed 21812955

Haakensen VD, Lingjaerde OC, Lüders T, Riis M, Prat A, Troester MA, Holmen MM, Frantzen JO, Romundstad L, Navjord D, Bukholm IK, Johannesen TB, Perou CM, Ursin G, Kristensen VN, Børresen-Dale AL, Helland A (2011)
Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features
BMC Med Genomics, 4, 77
PubMed 22044755

Kamalakaran S, Varadan V, Giercksky Russnes HE, Levy D, Kendall J, Janevski A, Riggs M, Banerjee N, Synnestvedt M, Schlichting E, Kåresen R, Shama Prasada K, Rotti H, Rao R, Rao L, Eric Tang MH, Satyamoorthy K, Lucito R, Wigler M, Dimitrova N, Naume B, Borresen-Dale AL, Hicks JB (2011)
DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables
Mol Oncol, 5 (1), 77-92
PubMed 21169070

Knappskog S, Bjørnslett M, Myklebust LM, Huijts PE, Vreeswijk MP, Edvardsen H, Guo Y, Zhang X, Yang M, Ylisaukko-Oja SK, Alhopuro P, Arola J, Tollenaar RA, van Asperen CJ, Seynaeve C, Staalesen V, Chrisanthar R, Løkkevik E, Salvesen HB, Evans DG, Newman WG, Lin D, Aaltonen LA, Børresen-Dale AL, Tell GS et al. (2011)
The MDM2 promoter SNP285C/309G haplotype diminishes Sp1 transcription factor binding and reduces risk for breast and ovarian cancer in Caucasians
Cancer Cell, 19 (2), 273-82
PubMed 21316605

Landmark-Høyvik H, Dumeaux V, Reinertsen KV, Edvardsen H, Fosså SD, Børresen-Dale AL (2011)
Blood gene expression profiling of breast cancer survivors experiencing fibrosis
Int J Radiat Oncol Biol Phys, 79 (3), 875-83
PubMed 21129856

Perou CM, Børresen-Dale AL (2011)
Systems biology and genomics of breast cancer
Cold Spring Harb Perspect Biol, 3 (2)
PubMed 21047916

Russnes HG, Kuligina ESh, Suspitsin EN, Voskresenskiy DA, Jordanova ES, Cornelisse CJ, Borresen-Dale AL, Imyanitov EN (2011)
Paired distribution of molecular subtypes in bilateral breast carcinomas
Cancer Genet, 204 (2), 96-102
PubMed 21504707

Russnes HG, Navin N, Hicks J, Borresen-Dale AL (2011)
Insight into the heterogeneity of breast cancer through next-generation sequencing
J Clin Invest, 121 (10), 3810-8
PubMed 21965338

Rønneberg JA, Fleischer T, Solvang HK, Nordgard SH, Edvardsen H, Potapenko I, Nebdal D, Daviaud C, Gut I, Bukholm I, Naume B, Børresen-Dale AL, Tost J, Kristensen V (2011)
Methylation profiling with a panel of cancer related genes: association with estrogen receptor, TP53 mutation status and expression subtypes in sporadic breast cancer
Mol Oncol, 5 (1), 61-76
PubMed 21212030

Solvang HK, Lingjærde OC, Frigessi A, Børresen-Dale AL, Kristensen VN (2011)
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in breast cancer
BMC Bioinformatics, 12, 197
PubMed 21609452

Westbury CB, Sahlberg KK, Borresen-Dale AL, Isacke CM, Yarnold JR (2011)
Gene expression profiling of human dermal fibroblasts exposed to bleomycin sulphate does not differentiate between radiation sensitive and control patients
Radiat Oncol, 6, 42
PubMed 21521514

Zhao X, Rødland EA, Sørlie T, Naume B, Langerød A, Frigessi A, Kristensen VN, Børresen-Dale AL, Lingjærde OC (2011)
Combining gene signatures improves prediction of breast cancer survival
PLoS One, 6 (3), e17845
PubMed 21423775

Publications 2010

Avraham R, Sas-Chen A, Manor O, Steinfeld I, Shalgi R, Tarcic G, Bossel N, Zeisel A, Amit I, Zwang Y, Enerly E, Russnes HG, Biagioni F, Mottolese M, Strano S, Blandino G, Børresen-Dale AL, Pilpel Y, Yakhini Z, Segal E, Yarden Y (2010)
EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors
Sci Signal, 3 (124), ra43
PubMed 20516477

Berge EO, Knappskog S, Geisler S, Staalesen V, Pacal M, Børresen-Dale AL, Puntervoll P, Lillehaug JR, Lønning PE (2010)
Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers
Mol Cancer, 9, 173
PubMed 20594292

Bernstein JL, Haile RW, Stovall M, Boice JD, Shore RE, Langholz B, Thomas DC, Bernstein L, Lynch CF, Olsen JH, Malone KE, Mellemkjaer L, Borresen-Dale AL, Rosenstein BS, Teraoka SN, Diep AT, Smith SA, Capanu M, Reiner AS, Liang X, Gatti RA, Concannon P, WECARE Study Collaborative Group (2010)
Radiation exposure, the ATM Gene, and contralateral breast cancer in the women's environmental cancer and radiation epidemiology study
J Natl Cancer Inst, 102 (7), 475-83
PubMed 20305132

Bocanegra M, Bergamaschi A, Kim YH, Miller MA, Rajput AB, Kao J, Langerød A, Han W, Noh DY, Jeffrey SS, Huntsman DG, Børresen-Dale AL, Pollack JR (2010)
Focal amplification and oncogene dependency of GAB2 in breast cancer
Oncogene, 29 (5), 774-9
PubMed 19881546

Borg A, Haile RW, Malone KE, Capanu M, Diep A, Törngren T, Teraoka S, Begg CB, Thomas DC, Concannon P, Mellemkjaer L, Bernstein L, Tellhed L, Xue S, Olson ER, Liang X, Dolle J, Børresen-Dale AL, Bernstein JL (2010)
Characterization of BRCA1 and BRCA2 deleterious mutations and variants of unknown clinical significance in unilateral and bilateral breast cancer: the WECARE study
Hum Mutat, 31 (3), E1200-40
PubMed 20104584

Borgan E, Sitter B, Lingjærde OC, Johnsen H, Lundgren S, Bathen TF, Sørlie T, Børresen-Dale AL, Gribbestad IS (2010)
Merging transcriptomics and metabolomics--advances in breast cancer profiling
BMC Cancer, 10, 628
PubMed 21080935

Borresen-Dale AL (2010)
Europe's largest Member Association for Cancer Research
Period. Biol., 112 (4), 483-485

Børresen-Dale AL, Sørlie T, Kristensen VN (2010)
On the molecular biology of breast cancer
Mol Oncol, 4 (3), 171-3
PubMed 20483673

de Neergaard M, Kim J, Villadsen R, Fridriksdottir AJ, Rank F, Timmermans-Wielenga V, Langerød A, Børresen-Dale AL, Petersen OW, Rønnov-Jessen L (2010)
Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment
Am J Pathol, 176 (3), 1229-40
PubMed 20133812

Dejeux E, Rønneberg JA, Solvang H, Bukholm I, Geisler S, Aas T, Gut IG, Børresen-Dale AL, Lønning PE, Kristensen VN, Tost J (2010)
DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response
Mol Cancer, 9, 68
PubMed 20338046

Dumeaux V, Olsen KS, Nuel G, Paulssen RH, Børresen-Dale AL, Lund E (2010)
Deciphering normal blood gene expression variation--The NOWAC postgenome study
PLoS Genet, 6 (3), e1000873
PubMed 20300640

Edvardsen H, Brunsvig PF, Solvang H, Tsalenko A, Andersen A, Syvanen AC, Yakhini Z, Børresen-Dale AL, Olsen H, Aamdal S, Kristensen VN (2010)
SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance
Pharmacogenomics J, 10 (6), 513-23
PubMed 20157331

Figueiredo JC, Haile RW, Bernstein L, Malone KE, Largent J, Langholz B, Lynch CF, Bertelsen L, Capanu M, Concannon P, Borg A, Børresen-Dale AL, Diep A, Teraoka S, Torngren T, Xue S, Bernstein JL (2010)
Oral contraceptives and postmenopausal hormones and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers and noncarriers: the WECARE Study
Breast Cancer Res Treat, 120 (1), 175-83
PubMed 19597986

Fu YP, Edvardsen H, Kaushiva A, Arhancet JP, Howe TM, Kohaar I, Porter-Gill P, Shah A, Landmark-Høyvik H, Fosså SD, Ambs S, Naume B, Børresen-Dale AL, Kristensen VN, Prokunina-Olsson L (2010)
NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations
Mol Cancer, 9, 113
PubMed 20482849

Hennessy BT, Lu Y, Gonzalez-Angulo AM, Carey MS, Myhre S, Ju Z, Davies MA, Liu W, Coombes K, Meric-Bernstam F, Bedrosian I, McGahren M, Agarwal R, Zhang F, Overgaard J, Alsner J, Neve RM, Kuo WL, Gray JW, Borresen-Dale AL, Mills GB (2010)
A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers
Clin Proteomics, 6 (4), 129-51
PubMed 21691416

Holstege H, Horlings HM, Velds A, Langerød A, Børresen-Dale AL, van de Vijver MJ, Nederlof PM, Jonkers J (2010)
BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations
BMC Cancer, 10, 654
PubMed 21118481

Haakensen VD, Biong M, Lingjærde OC, Holmen MM, Frantzen JO, Chen Y, Navjord D, Romundstad L, Lüders T, Bukholm IK, Solvang HK, Kristensen VN, Ursin G, Børresen-Dale AL, Helland A (2010)
Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density
Breast Cancer Res, 12 (4), R65
PubMed 20799965

International Cancer Genome Consortium, Hudson TJ, Anderson W, Artez A, Barker AD, Bell C, Bernabé RR, Bhan MK, Calvo F, Eerola I, Gerhard DS, Guttmacher A, Guyer M, Hemsley FM, Jennings JL, Kerr D, Klatt P, Kolar P, Kusada J, Lane DP, Laplace F, Youyong L, Nettekoven G, Ozenberger B, Peterson J et al. (2010)
International network of cancer genome projects
Nature, 464 (7291), 993-8
PubMed 20393554

Kristensen V, Borresen-Dale AL (2010)
Mutations for the people
EMBO Mol Med, 2 (5), 143-5
PubMed 20461736

Landmark-Høyvik H, Reinertsen KV, Loge JH, Kristensen VN, Dumeaux V, Fosså SD, Børresen-Dale AL, Edvardsen H (2010)
The genetics and epigenetics of fatigue
PM R, 2 (5), 456-65
PubMed 20656628

Moestue SA, Borgan E, Huuse EM, Lindholm EM, Sitter B, Børresen-Dale AL, Engebraaten O, Maelandsmo GM, Gribbestad IS (2010)
Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models
BMC Cancer, 10, 433
PubMed 20716336

Muggerud AA, Hallett M, Johnsen H, Kleivi K, Zhou W, Tahmasebpoor S, Amini RM, Botling J, Børresen-Dale AL, Sørlie T, Wärnberg F (2010)
Molecular diversity in ductal carcinoma in situ (DCIS) and early invasive breast cancer
Mol Oncol, 4 (4), 357-68
PubMed 20663721

Muggerud AA, Rønneberg JA, Wärnberg F, Botling J, Busato F, Jovanovic J, Solvang H, Bukholm I, Børresen-Dale AL, Kristensen VN, Sørlie T, Tost J (2010)
Frequent aberrant DNA methylation of ABCB1, FOXC1, PPP2R2B and PTEN in ductal carcinoma in situ and early invasive breast cancer
Breast Cancer Res, 12 (1), R3
PubMed 20056007

Myhre S, Mohammed H, Tramm T, Alsner J, Finak G, Park M, Overgaard J, Børresen-Dale AL, Frigessi A, Sørlie T (2010)
In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome
PLoS One, 5 (11), e14002
PubMed 21124964

Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Stromberg M, Wiedswang G, Kvalheim G, Karesen R, Nesland JM, Borresen-Dale AL, Sorlie T (2010)
Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer (vol 1, pg 160, 2007)
Mol. Oncol., 4 (2), 169

Papp J, Kovacs ME, Solyom S, Kasler M, Børresen-Dale AL, Olah E (2010)
High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients
BMC Med Genet, 11, 169
PubMed 21118512

Podo F, Buydens LM, Degani H, Hilhorst R, Klipp E, Gribbestad IS, Van Huffel S, van Laarhoven HW, Luts J, Monleon D, Postma GJ, Schneiderhan-Marra N, Santoro F, Wouters H, Russnes HG, Sørlie T, Tagliabue E, Børresen-Dale AL, FEMME Consortium (2010)
Triple-negative breast cancer: present challenges and new perspectives
Mol Oncol, 4 (3), 209-29
PubMed 20537966

Potapenko IO, Haakensen VD, Lüders T, Helland A, Bukholm I, Sørlie T, Kristensen VN, Lingjaerde OC, Børresen-Dale AL (2010)
Glycan gene expression signatures in normal and malignant breast tissue; possible role in diagnosis and progression
Mol Oncol, 4 (2), 98-118
PubMed 20060370

Russnes HG, Vollan HK, Lingjaerde OC, Krasnitz A, Lundin P, Naume B, Sørlie T, Borgen E, Rye IH, Langerød A, Chin SF, Teschendorff AE, Stephens PJ, Månér S, Schlichting E, Baumbusch LO, Kåresen R, Stratton MP, Wigler M, Caldas C, Zetterberg A, Hicks J, Børresen-Dale AL (2010)
Genomic architecture characterizes tumor progression paths and fate in breast cancer patients
Sci Transl Med, 2 (38), 38ra47
PubMed 20592421

Sørlie T, Borgan E, Myhre S, Vollan HK, Russnes H, Zhao X, Nilsen G, Lingjaerde OC, Børresen-Dale AL, Rødland E (2010)
The importance of gene-centring microarray data
Lancet Oncol, 11 (8), 719-20; author reply 720-1
PubMed 20688275

Van Loo P, Nordgard SH, Lingjærde OC, Russnes HG, Rye IH, Sun W, Weigman VJ, Marynen P, Zetterberg A, Naume B, Perou CM, Børresen-Dale AL, Kristensen VN (2010)
Allele-specific copy number analysis of tumors
Proc Natl Acad Sci U S A, 107 (39), 16910-5
PubMed 20837533

Aarøe J, Lindahl T, Dumeaux V, Saebø S, Tobin D, Hagen N, Skaane P, Lönneborg A, Sharma P, Børresen-Dale AL (2010)
Gene expression profiling of peripheral blood cells for early detection of breast cancer
Breast Cancer Res, 12 (1), R7
PubMed 20078854

Publications 2009

Agarwal R, Gonzalez-Angulo AM, Myhre S, Carey M, Lee JS, Overgaard J, Alsner J, Stemke-Hale K, Lluch A, Neve RM, Kuo WL, Sorlie T, Sahin A, Valero V, Keyomarsi K, Gray JW, Borresen-Dale AL, Mills GB, Hennessy BT (2009)
Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer
Clin Cancer Res, 15 (11), 3654-62
PubMed 19470724

Bergamaschi A, Hjortland GO, Triulzi T, Sørlie T, Johnsen H, Ree AH, Russnes HG, Tronnes S, Maelandsmo GM, Fodstad O, Borresen-Dale AL, Engebraaten O (2009)
Molecular profiling and characterization of luminal-like and basal-like in vivo breast cancer xenograft models
Mol Oncol, 3 (5-6), 469-82
PubMed 19713161

Dunning AM, Healey CS, Baynes C, Maia AT, Scollen S, Vega A, Rodríguez R, Barbosa-Morais NL, Ponder BA, SEARCH, Low YL, Bingham S, EPIC, Haiman CA, Le Marchand L, MEC, Broeks A, Schmidt MK, ABCS, Hopper J, Southey M, ABCFS, Beckmann MW, Fasching PA, BBCC et al. (2009)
Association of ESR1 gene tagging SNPs with breast cancer risk
Hum Mol Genet, 18 (6), 1131-9
PubMed 19126777

Glynn SA, Boersma BJ, Howe TM, Edvardsen H, Geisler SB, Goodman JE, Ridnour LA, Lønning PE, Børresen-Dale AL, Naume B, Kristensen VN, Chanock SJ, Wink DA, Ambs S (2009)
A mitochondrial target sequence polymorphism in manganese superoxide dismutase predicts inferior survival in breast cancer patients treated with cyclophosphamide
Clin Cancer Res, 15 (12), 4165-73
PubMed 19509150

Kamalakaran S, Kendall J, Zhao X, Tang C, Khan S, Ravi K, Auletta T, Riggs M, Wang Y, Helland A, Naume B, Dimitrova N, Børresen-Dale AL, Hicks J, Lucito R (2009)
Methylation detection oligonucleotide microarray analysis: a high-resolution method for detection of CpG island methylation
Nucleic Acids Res, 37 (12), e89
PubMed 19474344

Landmark-Høyvik H, Reinertsen KV, Loge JH, Fosså SD, Børresen-Dale AL, Dumeaux V (2009)
Alterations of gene expression in blood cells associated with chronic fatigue in breast cancer survivors
Pharmacogenomics J, 9 (5), 333-40
PubMed 19546881

Leivonen SK, Mäkelä R, Ostling P, Kohonen P, Haapa-Paananen S, Kleivi K, Enerly E, Aakula A, Hellström K, Sahlberg N, Kristensen VN, Børresen-Dale AL, Saviranta P, Perälä M, Kallioniemi O (2009)
Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines
Oncogene, 28 (44), 3926-36
PubMed 19684618

Lönneborg A, Aarøe J, Dumeaux V, Børresen-Dale AL (2009)
Found in transcription: gene expression and other novel blood biomarkers for the early detection of breast cancer
Expert Rev Anticancer Ther, 9 (8), 1115-23
PubMed 19671031

Murph MM, Liu W, Yu S, Lu Y, Hall H, Hennessy BT, Lahad J, Schaner M, Helland A, Kristensen G, Børresen-Dale AL, Mills GB (2009)
Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis
PLoS One, 4 (5), e5583
PubMed 19440550

Stephens PJ, McBride DJ, Lin ML, Varela I, Pleasance ED, Simpson JT, Stebbings LA, Leroy C, Edkins S, Mudie LJ, Greenman CD, Jia M, Latimer C, Teague JW, Lau KW, Burton J, Quail MA, Swerdlow H, Churcher C, Natrajan R, Sieuwerts AM, Martens JW, Silver DP, Langerød A, Russnes HE et al. (2009)
Complex landscapes of somatic rearrangement in human breast cancer genomes
Nature, 462 (7276), 1005-10
PubMed 20033038

Zhou W, Muggerud AA, Vu P, Due EU, Sørlie T, Børresen-Dale AL, Wärnberg F, Langerød A (2009)
Full sequencing of TP53 identifies identical mutations within in situ and invasive components in breast cancer suggesting clonal evolution
Mol Oncol, 3 (3), 214-9
PubMed 19403344

Publications 2008

Alsner J, Jensen V, Kyndi M, Offersen BV, Vu P, Børresen-Dale AL, Overgaard J (2008)
A comparison between p53 accumulation determined by immunohistochemistry and TP53 mutations as prognostic variables in tumours from breast cancer patients
Acta Oncol, 47 (4), 600-7
PubMed 18465328

Baumbusch LO, Aarøe J, Johansen FE, Hicks J, Sun H, Bruhn L, Gunderson K, Naume B, Kristensen VN, Liestøl K, Børresen-Dale AL, Lingjaerde OC (2008)
Comparison of the Agilent, ROMA/NimbleGen and Illumina platforms for classification of copy number alterations in human breast tumors
BMC Genomics, 9, 379
PubMed 18691401

Bergamaschi A, Kim YH, Kwei KA, La Choi Y, Bocanegra M, Langerød A, Han W, Noh DY, Huntsman DG, Jeffrey SS, Børresen-Dale AL, Pollack JR (2008)
CAMK1D amplification implicated in epithelial-mesenchymal transition in basal-like breast cancer
Mol Oncol, 2 (4), 327-39
PubMed 19383354

Bergamaschi A, Tagliabue E, Sørlie T, Naume B, Triulzi T, Orlandi R, Russnes HG, Nesland JM, Tammi R, Auvinen P, Kosma VM, Ménard S, Børresen-Dale AL (2008)
Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome
J Pathol, 214 (3), 357-67
PubMed 18044827

Brosh R, Shalgi R, Liran A, Landan G, Korotayev K, Nguyen GH, Enerly E, Johnsen H, Buganim Y, Solomon H, Goldstein I, Madar S, Goldfinger N, Børresen-Dale AL, Ginsberg D, Harris CC, Pilpel Y, Oren M, Rotter V (2008)
p53-Repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation
Mol Syst Biol, 4, 229
PubMed 19034270

Concannon P, Haile RW, Børresen-Dale AL, Rosenstein BS, Gatti RA, Teraoka SN, Diep TA, Jansen L, Atencio DP, Langholz B, Capanu M, Liang X, Begg CB, Thomas DC, Bernstein L, Olsen JH, Malone KE, Lynch CF, Anton-Culver H, Bernstein JL, Women's Environment, Cancer, and Radiation Epidemiology Study Collaborative Group (2008)
Variants in the ATM gene associated with a reduced risk of contralateral breast cancer
Cancer Res, 68 (16), 6486-91
PubMed 18701470

Dumeaux V, Børresen-Dale AL, Frantzen JO, Kumle M, Kristensen VN, Lund E (2008)
Gene expression analyses in breast cancer epidemiology: the Norwegian Women and Cancer postgenome cohort study
Breast Cancer Res, 10 (1), R13
PubMed 18271962

Dumeaux V, Lund E, Børresen-Dale AL (2008)
Comparison of globin RNA processing methods for genome-wide transcriptome analysis from whole blood
Biomark Med, 2 (1), 11-21
PubMed 20477359

Horlings HM, Bergamaschi A, Nordgard SH, Kim YH, Han W, Noh DY, Salari K, Joosse SA, Reyal F, Lingjaerde OC, Kristensen VN, Børresen-Dale AL, Pollack J, van de Vijver MJ (2008)
ESR1 gene amplification in breast cancer: a common phenomenon?
Nat Genet, 40 (7), 807-8; author reply 810-2
PubMed 18583965

Kristensen VN, Børresen-Dale AL (2008)
SNPs associated with molecular subtypes of breast cancer: on the usefulness of stratified Genome-wide Association Studies (GWAS) in the identification of novel susceptibility loci
Mol Oncol, 2 (1), 12-5
PubMed 19383324

Mellemkjaer L, Dahl C, Olsen JH, Bertelsen L, Guldberg P, Christensen J, Børresen-Dale AL, Stovall M, Langholz B, Bernstein L, Lynch CF, Malone KE, Haile RW, Andersson M, Thomas DC, Concannon P, Capanu M, Boice JD, WECARE Study Collaborative Group, Bernstein JL (2008)
Risk for contralateral breast cancer among carriers of the CHEK2*1100delC mutation in the WECARE Study
Br J Cancer, 98 (4), 728-33
PubMed 18253122

Nordgard SH, Alnaes GI, Hihn B, Lingjaerde OC, Liestøl K, Tsalenko A, Sørlie T, Lønning PE, Børresen-Dale AL, Kristensen VN (2008)
Pathway based analysis of SNPs with relevance to 5-FU therapy: relation to intratumoral mRNA expression and survival
Int J Cancer, 123 (3), 577-85
PubMed 18498133

Nordgard SH, Johansen FE, Alnaes GI, Bucher E, Syvänen AC, Naume B, Børresen-Dale AL, Kristensen VN (2008)
Genome-wide analysis identifies 16q deletion associated with survival, molecular subtypes, mRNA expression, and germline haplotypes in breast cancer patients
Genes Chromosomes Cancer, 47 (8), 680-96
PubMed 18398821

Roca X, Olson AJ, Rao AR, Enerly E, Kristensen VN, Børresen-Dale AL, Andresen BS, Krainer AR, Sachidanandam R (2008)
Features of 5'-splice-site efficiency derived from disease-causing mutations and comparative genomics
Genome Res, 18 (1), 77-87
PubMed 18032726

Rødningen OK, Børresen-Dale AL, Alsner J, Hastie T, Overgaard J (2008)
Radiation-induced gene expression in human subcutaneous fibroblasts is predictive of radiation-induced fibrosis
Radiother Oncol, 86 (3), 314-20
PubMed 17963910

Rønneberg JA, Tost J, Solvang HK, Alnaes GI, Johansen FE, Brendeford EM, Yakhini Z, Gut IG, Lønning PE, Børresen-Dale AL, Gabrielsen OS, Kristensen VN (2008)
GSTP1 promoter haplotypes affect DNA methylation levels and promoter activity in breast carcinomas
Cancer Res, 68 (14), 5562-71
PubMed 18632608

Suspitsin EN, Due EU, Vu P, Hirvonen A, Børresen-Dale AL, Imyanitov EN (2008)
TP53 mutations in synchronous and metachronous bilateral breast carcinomas
Cancer Genet Cytogenet, 184 (2), 119-21
PubMed 18617062

Tongbai R, Idelman G, Nordgard SH, Cui W, Jacobs JL, Haggerty CM, Chanock SJ, Børresen-Dale AL, Livingston G, Shaunessy P, Chiang CH, Kristensen VN, Bilke S, Gardner K (2008)
Transcriptional networks inferred from molecular signatures of breast cancer
Am J Pathol, 172 (2), 495-509
PubMed 18187569

Publications 2007

Casalini P, Iorio MV, Berno V, Bergamaschi A, Børresen Dale AL, Gasparini P, Orlandi R, Casati B, Tagliabue E, Ménard S (2007)
Relationship between p53 and p27 expression following HER2 signaling
Breast, 16 (6), 597-605
PubMed 17604627

Chanock SJ, Burdett L, Yeager M, Llaca V, Langerød A, Presswalla S, Kaaresen R, Strausberg RL, Gerhard DS, Kristensen V, Perou CM, Børresen-Dale AL (2007)
Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas
Breast Cancer Res, 9 (1), R5
PubMed 17224074

Edvardsen H, Kristensen VN, Grenaker Alnaes GI, Bøhn M, Erikstein B, Helland A, Børresen-Dale AL, Fosså SD (2007)
Germline glutathione S-transferase variants in breast cancer: relation to diagnosis and cutaneous long-term adverse effects after two fractionation patterns of radiotherapy
Int J Radiat Oncol Biol Phys, 67 (4), 1163-71
PubMed 17336217

Edvardsen H, Tefre T, Jansen L, Vu P, Haffty BG, Fosså SD, Kristensen VN, Børresen-Dale AL (2007)
Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence
Radiat Oncol, 2, 25
PubMed 17623063

Garcia-Closas M, Kristensen V, Langerød A, Qi Y, Yeager M, Burdett L, Welch R, Lissowska J, Peplonska B, Brinton L, Gerhard DS, Gram IT, Perou CM, Børresen-Dale AL, Chanock S (2007)
Common genetic variation in TP53 and its flanking genes, WDR79 and ATP1B2, and susceptibility to breast cancer
Int J Cancer, 121 (11), 2532-8
PubMed 17683073

Garcia-Closas M, Troester MA, Qi Y, Langerød A, Yeager M, Lissowska J, Brinton L, Welch R, Peplonska B, Gerhard DS, Gram IT, Kristensen V, Børresen-Dale AL, Chanock S, Perou CM (2007)
Common genetic variation in GATA-binding protein 3 and differential susceptibility to breast cancer by estrogen receptor alpha tumor status
Cancer Epidemiol Biomarkers Prev, 16 (11), 2269-75
PubMed 18006915

Irish JM, Anensen N, Hovland R, Skavland J, Børresen-Dale AL, Bruserud O, Nolan GP, Gjertsen BT (2007)
Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53
Blood, 109 (6), 2589-96
PubMed 17105820

Kapp AV, Jeffrey SS, Langerod A, Borresen-Dale AL, Han W, Noh DY, Bukholm IRK, Nicolau M, Brown PO, Tibshirani R (2007)
Discovery and validation of breast cancer subtypes (vol 8, pg 101, 2007)
BMC Genomics, 8, 101

Knappskog S, Chrisanthar R, Staalesen V, Børresen-Dale AL, Gram IT, Lillehaug JR, Lønning PE (2007)
Mutations and polymorphisms of the p21B transcript in breast cancer
Int J Cancer, 121 (4), 908-10
PubMed 17443496

Landmark H, Nahas SA, Aarøe J, Gatti R, Børresen-Dale AL, Rødningen OK (2007)
Transcriptional response to ionizing radiation in human radiation sensitive cell lines
Radiother Oncol, 83 (3), 256-60
PubMed 17512073

Langerød A, Zhao H, Borgan Ø, Nesland JM, Bukholm IR, Ikdahl T, Kåresen R, Børresen-Dale AL, Jeffrey SS (2007)
TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer
Breast Cancer Res, 9 (3), R30
PubMed 17504517

Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Strømberg M, Wiedswang G, Kvalheim G, Kåresen R, Nesland JM, Børresen-Dale AL, Sørlie T (2007)
Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer
Mol Oncol, 1 (2), 160-71
PubMed 19383292

Nicolau M, Tibshirani R, Børresen-Dale AL, Jeffrey SS (2007)
Disease-specific genomic analysis: identifying the signature of pathologic biology
Bioinformatics, 23 (8), 957-65
PubMed 17277331

Nordgard SH, Johansen FE, Alnaes GI, Naume B, Børresen-Dale AL, Kristensen VN (2007)
Genes harbouring susceptibility SNPs are differentially expressed in the breast cancer subtypes
Breast Cancer Res, 9 (6), 113
PubMed 18036273

Nordgard SH, Ritchie MD, Jensrud SD, Motsinger AA, Alnaes GI, Lemmon G, Berg M, Geisler S, Moore JH, Lønning PE, Børresen-Dale AL, Kristensen VN (2007)
ABCB1 and GST polymorphisms associated with TP53 status in breast cancer
Pharmacogenet Genomics, 17 (2), 127-36
PubMed 17301692

Petitjean A, Achatz MI, Borresen-Dale AL, Hainaut P, Olivier M (2007)
TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes
Oncogene, 26 (15), 2157-65
PubMed 17401424

Stray-Pedersen A, Borresen-Dale AL, Paus E, Lindman CR, Burgers T, Abrahamsen TG (2007)
Alpha fetoprotein is increasing with age in ataxia-telangiectasia
Eur J Paediatr Neurol, 11 (6), 375-80
PubMed 17540590

Størvold GL, Gjernes E, Askautrud HA, Børresen-Dale AL, Perou CM, Frengen E (2007)
A retroviral vector for siRNA expression in mammalian cells
Mol Biotechnol, 35 (3), 275-82
PubMed 17652791

Suspitsin EN, Sokolenko AP, Togo AV, Lazareva YR, Turkevich EA, Matsko DE, Henrich KO, Borresen-Dale AL, Schwab M, Cornelisse CJ, Imyanitov EN (2007)
Nonrandom distribution of oncogene amplifications in bilateral breast carcinomas: Possible role of host factors and survival bias
Int J Cancer, 120 (2), 297-302
PubMed 17066426

Wang Y, Kristensen GB, Børresen-Dale AL, Helland A (2007)
TP53 mutations and codon 72 genotype--impact on survival among ovarian cancer patients
Ann Oncol, 18 (5), 964-6
PubMed 17488735

Yosef N, Yakhini Z, Tsalenko A, Kristensen V, Børresen-Dale AL, Ruppin E, Sharan R (2007)
A supervised approach for identifying discriminating genotype patterns and its application to breast cancer data
Bioinformatics, 23 (2), e91-8
PubMed 17237111

Publications 2006

Anensen N, Skavland J, Stapnes C, Ryningen A, Børresen-Dale AL, Gjertsen BT, Bruserud Ø (2006)
Acute myelogenous leukemia in a patient with Li-Fraumeni syndrome treated with valproic acid, theophyllamine and all-trans retinoic acid: a case report
Leukemia, 20 (4), 734-6
PubMed 16437140

Baumbusch LO, Myhre S, Langerød A, Bergamaschi A, Geisler SB, Lønning PE, Deppert W, Dornreiter I, Børresen-Dale AL (2006)
Expression of full-length p53 and its isoform Deltap53 in breast carcinomas in relation to mutation status and clinical parameters
Mol Cancer, 5, 47
PubMed 17054774

Bergamaschi A, Kim YH, Wang P, Sørlie T, Hernandez-Boussard T, Lonning PE, Tibshirani R, Børresen-Dale AL, Pollack JR (2006)
Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer
Genes Chromosomes Cancer, 45 (11), 1033-40
PubMed 16897746

Chi JT, Wang Z, Nuyten DS, Rodriguez EH, Schaner ME, Salim A, Wang Y, Kristensen GB, Helland A, Børresen-Dale AL, Giaccia A, Longaker MT, Hastie T, Yang GP, van de Vijver MJ, Brown PO (2006)
Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers
PLoS Med, 3 (3), e47
PubMed 16417408

Dumeaux V, Johansen J, Børresen-Dale AL, Lund E (2006)
Gene expression profiling of whole-blood samples from women exposed to hormone replacement therapy
Mol Cancer Ther, 5 (4), 868-76
PubMed 16648556

Edvardsen H, Irene Grenaker Alnaes G, Tsalenko A, Mulcahy T, Yuryev A, Lindersson M, Lien S, Omholt S, Syvänen AC, Børresen-Dale AL, Kristensen VN (2006)
Experimental validation of data mined single nucleotide polymorphisms from several databases and consecutive dbSNP builds
Pharmacogenet Genomics, 16 (3), 207-17
PubMed 16495780

Heikkinen K, Rapakko K, Karppinen SM, Erkko H, Knuutila S, Lundán T, Mannermaa A, Børresen-Dale AL, Borg A, Barkardottir RB, Petrini J, Winqvist R (2006)
RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability
Carcinogenesis, 27 (8), 1593-9
PubMed 16474176

Helland A, Johnsen H, Frøyland C, Landmark HB, Saetersdal AB, Holmen MM, Gjertsen T, Nesland JM, Ottestad W, Jeffrey SS, Ottestad LO, Rodningen OK, Sherlock G, Børresen-Dale AL (2006)
Radiation-induced effects on gene expression: an in vivo study on breast cancer
Radiother Oncol, 80 (2), 230-5
PubMed 16890317

Hicks J, Krasnitz A, Lakshmi B, Navin NE, Riggs M, Leibu E, Esposito D, Alexander J, Troge J, Grubor V, Yoon S, Wigler M, Ye K, Børresen-Dale AL, Naume B, Schlicting E, Norton L, Hägerström T, Skoog L, Auer G, Månér S, Lundin P, Zetterberg A (2006)
Novel patterns of genome rearrangement and their association with survival in breast cancer
Genome Res, 16 (12), 1465-79
PubMed 17142309

Kapp AV, Jeffrey SS, Langerød A, Børresen-Dale AL, Han W, Noh DY, Bukholm IR, Nicolau M, Brown PO, Tibshirani R (2006)
Discovery and validation of breast cancer subtypes
BMC Genomics, 7, 231
PubMed 16965636

Kristensen VN, Edvardsen H, Tsalenko A, Nordgard SH, Sørlie T, Sharan R, Vailaya A, Ben-Dor A, Lønning PE, Lien S, Omholt S, Syvänen AC, Yakhini Z, Børresen-Dale AL (2006)
Genetic variation in putative regulatory loci controlling gene expression in breast cancer
Proc Natl Acad Sci U S A, 103 (20), 7735-40
PubMed 16684880

Kristensen VN, Tsalenko A, Geisler J, Faldaas A, Grenaker GI, Lingjaerde OC, Fjeldstad S, Yakhini Z, Lønning PE, Børresen-Dale AL (2006)
Multilocus analysis of SNP and metabolic data within a given pathway
BMC Genomics, 7, 5
PubMed 16412218

Langholz B, Bernstein JL, Bernstein L, Olsen JH, Børresen-Dale AL, Rosenstein BS, Gatti RA, WECARE Study Collaborative Group, Concannon P (2006)
On the proposed association of the ATM variants 5557G>A and IVS38-8T>C and bilateral breast cancer
Int J Cancer, 119 (3), 724-5
PubMed 16496408

Lønning PE, Børresen-Dale AL (2006)
Interaction between p53 staining and high-dose chemotherapy in breast cancer
Clin Cancer Res, 12 (7 Pt 1), 2289
PubMed 16609046

Muggerud AA, Johnsen H, Barnes DA, Steel A, Lønning PE, Naume B, Sørlie T, Børresen-Dale AL (2006)
Evaluation of MetriGenix custom 4D arrays applied for detection of breast cancer subtypes
BMC Cancer, 6, 59
PubMed 16536878

Olivier M, Langerød A, Carrieri P, Bergh J, Klaar S, Eyfjord J, Theillet C, Rodriguez C, Lidereau R, Bièche I, Varley J, Bignon Y, Uhrhammer N, Winqvist R, Jukkola-Vuorinen A, Niederacher D, Kato S, Ishioka C, Hainaut P, Børresen-Dale AL (2006)
The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer
Clin Cancer Res, 12 (4), 1157-67
PubMed 16489069

Staalesen V, Knappskog S, Chrisanthar R, Nordgard SH, Løkkevik E, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Gram IT, Kristensen VN, Børresen-Dale AL, Lillehaug JR, Lønning PE (2006)
The novel p21 polymorphism p21G251A is associated with locally advanced breast cancer
Clin Cancer Res, 12 (20 Pt 1), 6000-4
PubMed 17062672

Sørlie T, Perou CM, Fan C, Geisler S, Aas T, Nobel A, Anker G, Akslen LA, Botstein D, Børresen-Dale AL, Lønning PE (2006)
Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer
Mol Cancer Ther, 5 (11), 2914-8
PubMed 17121939

Sørlie T, Wang Y, Xiao C, Johnsen H, Naume B, Samaha RR, Børresen-Dale AL (2006)
Distinct molecular mechanisms underlying clinically relevant subtypes of breast cancer: gene expression analyses across three different platforms
BMC Genomics, 7, 127
PubMed 16729877

Tavtigian SV, Pierotti MA, Børresen-Dale AL (2006)
International Agency for Research on Cancer workshop on 'Expression array analyses in breast cancer taxonomy'
Breast Cancer Res, 8 (6), 303
PubMed 17096863

Tommiska J, Jansen L, Kilpivaara O, Edvardsen H, Kristensen V, Tamminen A, Aittomäki K, Blomqvist C, Børresen-Dale AL, Nevanlinna H (2006)
ATM variants and cancer risk in breast cancer patients from Southern Finland
BMC Cancer, 6, 209
PubMed 16914028

Tsalenko A, Sharan R, Kristensen V, Edvardsen H, Børresen-Dale AL, Ben-Dor A, Yakhini Z (2006)
Analysis of SNP-expression association matrices
J Bioinform Comput Biol, 4 (2), 259-74
PubMed 16819783

Publications 2005

Benetkiewicz M, Wang Y, Schaner M, Wang P, Mantripragada KK, Buckley PG, Kristensen G, Børresen-Dale AL, Dumanski JP (2005)
High-resolution gene copy number and expression profiling of human chromosome 22 in ovarian carcinomas
Genes Chromosomes Cancer, 42 (3), 228-37
PubMed 15578687

Kringen P, Bergamaschi A, Due EU, Wang Y, Tagliabue E, Nesland JM, Nehman A, Tönisson N, Børresen-Dale AL (2005)
Evaluation of arrayed primer extension for TP53 mutation detection in breast and ovarian carcinomas
Biotechniques, 39 (5), 755-61
PubMed 16312222

Kringen P, Wang Y, Dumeaux V, Nesland JM, Kristensen G, Borresen-Dale AL, Dorum A (2005)
TP53 mutations in ovarian carcinomas from sporadic cases and carriers of two distinct BRCA1 founder mutations; relation to age at diagnosis and survival
BMC Cancer, 5, 134
PubMed 16229746

Kristensen VN, Sørlie T, Geisler J, Langerød A, Yoshimura N, Kåresen R, Harada N, Lønning PE, Børresen-Dale AL (2005)
Gene expression profiling of breast cancer in relation to estrogen receptor status and estrogen-metabolizing enzymes: clinical implications
Clin Cancer Res, 11 (2 Pt 2), 878s-83s
PubMed 15701881

Kristensen VN, Sørlie T, Geisler J, Yoshimura N, Linegjaerde OC, Glad I, Frigessi A, Harada N, Lønning PE, Børresen-Dale AL (2005)
Effects of anastrozole on the intratumoral gene expression in locally advanced breast cancer
J Steroid Biochem Mol Biol, 95 (1-5), 105-11
PubMed 16023338

Lingjaerde OC, Baumbusch LO, Liestøl K, Glad IK, Børresen-Dale AL (2005)
CGH-Explorer: a program for analysis of array-CGH data
Bioinformatics, 21 (6), 821-2
PubMed 15531610

Lønning PE, Sørlie T, Børresen-Dale AL (2005)
Genomics in breast cancer-therapeutic implications
Nat Clin Pract Oncol, 2 (1), 26-33
PubMed 16264853

Maguire P, Margolin S, Skoglund J, Sun XF, Gustafsson JA, Børresen-Dale AL, Lindblom A (2005)
Estrogen receptor beta (ESR2) polymorphisms in familial and sporadic breast cancer
Breast Cancer Res Treat, 94 (2), 145-52
PubMed 16261413

Olsen JH, Hahnemann JM, Børresen-Dale AL, Tretli S, Kleinerman R, Sankila R, Hammarström L, Robsahm TE, Kääriäinen H, Bregård A, Brøndum-Nielsen K, Yuen J, Tucker M (2005)
Breast and other cancers in 1445 blood relatives of 75 Nordic patients with ataxia telangiectasia
Br J Cancer, 93 (2), 260-5
PubMed 15942625

Rødningen OK, Overgaard J, Alsner J, Hastie T, Børresen-Dale AL (2005)
Microarray analysis of the transcriptional response to single or multiple doses of ionizing radiation in human subcutaneous fibroblasts
Radiother Oncol, 77 (3), 231-40
PubMed 16297999

Schaner ME, Davidson B, Skrede M, Reich R, Flørenes VA, Risberg B, Berner A, Goldberg I, Givant-Horwitz V, Tropè CG, Kristensen GB, Nesland JM, Børresen-Dale AL (2005)
Variation in gene expression patterns in effusions and primary tumors from serous ovarian cancer patients
Mol Cancer, 4, 26
PubMed 16042759

Sharma P, Sahni NS, Tibshirani R, Skaane P, Urdal P, Berghagen H, Jensen M, Kristiansen L, Moen C, Sharma P, Zaka A, Arnes J, Sauer T, Akslen LA, Schlichting E, Børresen-Dale AL, Lönneborg A (2005)
Early detection of breast cancer based on gene-expression patterns in peripheral blood cells
Breast Cancer Res, 7 (5), R634-44
PubMed 16168108

Sørlie T, Johnsen H, Vu P, Lind GE, Lothe R, Børresen-Dale AL (2005)
Mutation screening of the TP53 gene by temporal temperature gradient gel electrophoresis
Methods Mol Biol, 291, 207-16
PubMed 15502225

Tsalenko A, Sharan R, Edvardsen H, Kristensen V, Børresen-Dale AL, Ben-Dor A, Yakhini Z (2005)
Analysis of SNP-expression association matrices
Proc IEEE Comput Syst Bioinform Conf, 135-43
PubMed 16447971

Wang Y, Helland A, Holm R, Kristensen GB, Børresen-Dale AL (2005)
PIK3CA mutations in advanced ovarian carcinomas
Hum Mutat, 25 (3), 322
PubMed 15712344

Wang Y, Kristensen GB, Helland A, Nesland JM, Børresen-Dale AL, Holm R (2005)
Protein expression and prognostic value of genes in the erb-b signaling pathway in advanced ovarian carcinomas
Am J Clin Pathol, 124 (3), 392-401
PubMed 16191507

Aas T, Geisler S, Helle H, Børresen-Dale AL, Lønning PE, Akslen LA (2005)
Prognostic and predictive value of changes in tumour cell proliferation in locally advanced breast cancer primarily treated with doxorubicin
Oncol Rep, 13 (3), 525-30
PubMed 15706428

Publications 2004

Bernstein JL, Langholz B, Haile RW, Bernstein L, Thomas DC, Stovall M, Malone KE, Lynch CF, Olsen JH, Anton-Culver H, Shore RE, Boice JD, Berkowitz GS, Gatti RA, Teitelbaum SL, Smith SA, Rosenstein BS, Børresen-Dale AL, Concannon P, Thompson WD, WECARE study (2004)
Study design: evaluating gene-environment interactions in the etiology of breast cancer - the WECARE study
Breast Cancer Res, 6 (3), R199-214
PubMed 15084244

Stray-Pedersen A, Jónsson T, Heiberg A, Lindman CR, Widing E, Aaberge IS, Borresen-Dale AL, Abrahamsen TG (2004)
The impact of an early truncating founder ATM mutation on immunoglobulins, specific antibodies and lymphocyte populations in ataxia-telangiectasia patients and their parents
Clin Exp Immunol, 137 (1), 179-86
PubMed 15196260

Staalesen V, Falck J, Geisler S, Bartkova J, Børresen-Dale AL, Lukas J, Lillehaug JR, Bartek J, Lønning PE (2004)
Alternative splicing and mutation status of CHEK2 in stage III breast cancer
Oncogene, 23 (52), 8535-44
PubMed 15361853

Troester MA, Hoadley KA, Sørlie T, Herbert BS, Børresen-Dale AL, Lønning PE, Shay JW, Kaufmann WK, Perou CM (2004)
Cell-type-specific responses to chemotherapeutics in breast cancer
Cancer Res, 64 (12), 4218-26
PubMed 15205334

Usary J, Llaca V, Karaca G, Presswala S, Karaca M, He X, Langerød A, Kåresen R, Oh DS, Dressler LG, Lønning PE, Strausberg RL, Chanock S, Børresen-Dale AL, Perou CM (2004)
Mutation of GATA3 in human breast tumors
Oncogene, 23 (46), 7669-78
PubMed 15361840

Wang Y, Helland A, Holm R, Skomedal H, Abeler VM, Danielsen HE, Tropé CG, Børresen-Dale AL, Kristensen GB (2004)
TP53 mutations in early-stage ovarian carcinoma, relation to long-term survival
Br J Cancer, 90 (3), 678-85
PubMed 14760384

Wang Y, Kringen P, Kristensen GB, Holm R, Baekelandt MM, Olivier M, Skomedal H, Hainaut P, Tropé CG, Abeler VM, Nesland JM, Børresen-Dale AL, Helland A (2004)
Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in the TP53 gene on survival in patients with advanced ovarian carcinoma
Hum Mutat, 24 (1), 21-34
PubMed 15221786

Yoshimura N, Harada N, Bukholm I, Kåresen R, Børresen-Dale AL, Kristensen VN (2004)
Intratumoural mRNA expression of genes from the oestradiol metabolic pathway and clinical and histopathological parameters of breast cancer
Breast Cancer Res, 6 (2), R46-55
PubMed 14979917

Zhao H, Langerød A, Ji Y, Nowels KW, Nesland JM, Tibshirani R, Bukholm IK, Kåresen R, Botstein D, Børresen-Dale AL, Jeffrey SS (2004)
Different gene expression patterns in invasive lobular and ductal carcinomas of the breast
Mol Biol Cell, 15 (6), 2523-36
PubMed 15034139

Publications 2003

Bernstein JL, Bernstein L, Thompson WD, Lynch CF, Malone KE, Teitelbaum SL, Olsen JH, Anton-Culver H, Boice JD, Rosenstein BS, Børresen-Dale AL, Gatti RA, Concannon P, Haile RW, WECARE Study Collaborative Group (2003)
ATM variants 7271T>G and IVS10-6T>G among women with unilateral and bilateral breast cancer
Br J Cancer, 89 (8), 1513-6
PubMed 14562025

Bernstein JL, Teraoka S, Haile RW, Børresen-Dale AL, Rosenstein BS, Gatti RA, Diep AT, Jansen L, Atencio DP, Olsen JH, Bernstein L, Teitelbaum SL, Thompson WD, Concannon P, WECARE Study Collaborative Group (2003)
Designing and implementing quality control for multi-center screening of mutations in the ATM gene among women with breast cancer
Hum Mutat, 21 (5), 542-50
PubMed 12673797

Børresen-Dale AL (2003)
Genetic profiling of breast cancer: from molecular portraits to clinical utility
Int J Biol Markers, 18 (1), 54-6
PubMed 12699064

Børresen-Dale AL (2003)
TP53 and breast cancer
Hum Mutat, 21 (3), 292-300
PubMed 12619115

Geisler S, Børresen-Dale AL, Johnsen H, Aas T, Geisler J, Akslen LA, Anker G, Lønning PE (2003)
TP53 gene mutations predict the response to neoadjuvant treatment with 5-fluorouracil and mitomycin in locally advanced breast cancer
Clin Cancer Res, 9 (15), 5582-8
PubMed 14654539

Kristiansen M, Helland A, Kristensen GB, Olsen AO, Lønning PE, Børresen-Dale AL, Ørstavik KH (2003)
X chromosome inactivation in cervical cancer patients
Cancer Genet Cytogenet, 146 (1), 73-6
PubMed 14499700

Langerød A, Strømberg M, Chin K, Kristensen VN, Børresen-Dale AL (2003)
BUB1 infrequently mutated in human breast carcinomas
Hum Mutat, 22 (5), 420
PubMed 14517964

Pan-Hammarström Q, Dai S, Zhao Y, van Dijk-Härd IF, Gatti RA, Børresen-Dale AL, Hammarström L (2003)
ATM is not required in somatic hypermutation of VH, but is involved in the introduction of mutations in the switch mu region
J Immunol, 170 (7), 3707-16
PubMed 12646636

Schaner ME, Ross DT, Ciaravino G, Sorlie T, Troyanskaya O, Diehn M, Wang YC, Duran GE, Sikic TL, Caldeira S, Skomedal H, Tu IP, Hernandez-Boussard T, Johnson SW, O'Dwyer PJ, Fero MJ, Kristensen GB, Borresen-Dale AL, Hastie T, Tibshirani R, van de Rijn M, Teng NN, Longacre TA, Botstein D, Brown PO et al. (2003)
Gene expression patterns in ovarian carcinomas
Mol Biol Cell, 14 (11), 4376-86
PubMed 12960427

Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, Demeter J, Perou CM, Lønning PE, Brown PO, Børresen-Dale AL, Botstein D (2003)
Repeated observation of breast tumor subtypes in independent gene expression data sets
Proc Natl Acad Sci U S A, 100 (14), 8418-23
PubMed 12829800

Soucek P, Gut I, Trneny M, Skovlund E, Grenaker Alnaes G, Kristensen T, Børresen-Dale AL, Kristensen VN (2003)
Multiplex single-tube screening for mutations in the Nijmegen Breakage Syndrome (NBS1) gene in Hodgkin's and non-Hodgkin's lymphoma patients of Slavic origin
Eur J Hum Genet, 11 (5), 416-9
PubMed 12734548

Aas T, Geisler S, Eide GE, Haugen DF, Varhaug JE, Bassøe AM, Thorsen T, Berntsen H, Børresen-Dale AL, Akslen LA, Lønning PE (2003)
Predictive value of tumour cell proliferation in locally advanced breast cancer treated with neoadjuvant chemotherapy
Eur J Cancer, 39 (4), 438-46
PubMed 12751373

Publications 2002

Allinen M, Launonen V, Laake K, Jansen L, Huusko P, Kääriäinen H, Børresen-Dale AL, Winqvist R (2002)
ATM mutations in Finnish breast cancer patients
J Med Genet, 39 (3), 192-6
PubMed 11897822

Bernstein JL, Seminara D, Børresen-Dale AL (2002)
Workshop on The Epidemiology of the ATM Gene: Impact on Breast Cancer Risk and Treatment, Present Status and Future Focus, Lillehammer, Norway, 29 June 2002
Breast Cancer Res, 4 (6), 249-52
PubMed 12473172

Børresen AL (2002)
Mismatch detection using heteroduplex analysis
Curr Protoc Hum Genet, Chapter 7, Unit 7.3
PubMed 18428333

Jeffrey SS, Fero MJ, Børresen-Dale AL, Botstein D (2002)
Expression array technology in the diagnosis and treatment of breast cancer
Mol Interv, 2 (2), 101-9
PubMed 14993355

Kringen P, Egedal S, Pedersen JC, Harbitz TB, Tveit KM, Berg K, Børresen-Dale AL, Andersen TI (2002)
BRCA1 mutation screening using restriction endonuclease fingerprinting-single-strand conformation polymorphism in an automated capillary electrophoresis system
Electrophoresis, 23 (24), 4085-91
PubMed 12481264

Kristiansen M, Langerød A, Knudsen GP, Weber BL, Børresen-Dale AL, Orstavik KH (2002)
High frequency of skewed X inactivation in young breast cancer patients
J Med Genet, 39 (1), 30-3
PubMed 11826021

Langerød A, Bukholm IR, Bregård A, Lønning PE, Andersen TI, Rognum TO, Meling GI, Lothe RA, Børresen-Dale AL (2002)
The TP53 codon 72 polymorphism may affect the function of TP53 mutations in breast carcinomas but not in colorectal carcinomas
Cancer Epidemiol Biomarkers Prev, 11 (12), 1684-8
PubMed 12496062

Passarino G, Cavalleri GL, Lin AA, Cavalli-Sforza LL, Børresen-Dale AL, Underhill PA (2002)
Different genetic components in the Norwegian population revealed by the analysis of mtDNA and Y chromosome polymorphisms
Eur J Hum Genet, 10 (9), 521-9
PubMed 12173029

Pollack JR, Sørlie T, Perou CM, Rees CA, Jeffrey SS, Lonning PE, Tibshirani R, Botstein D, Børresen-Dale AL, Brown PO (2002)
Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors
Proc Natl Acad Sci U S A, 99 (20), 12963-8
PubMed 12297621

Zhao H, Hastie T, Whitfield ML, Børresen-Dale AL, Jeffrey SS (2002)
Optimization and evaluation of T7 based RNA linear amplification protocols for cDNA microarray analysis
BMC Genomics, 3 (1), 31
PubMed 12445333

Publications 2001

Bjørheim J, Ekstrøm PO, Fossberg E, Børresen-Dale AL, Gaudernack G (2001)
Automated constant denaturant capillary electrophoresis applied for detection of KRAS exon 1 mutations
Biotechniques, 30 (5), 972-5
PubMed 11355359

Børresen-Dale AL, Hovig E, Smith-Sørensen B (2001)
Detection of mutations by denaturing gradient gel electrophoresis
Curr Protoc Hum Genet, Chapter 7, Unit 7.5
PubMed 18428306

Dai H, Holm R, Kristensen GB, Abeler VM, Børresen-Dale AL, Helland A (2001)
Fibroblast growth factor receptor 3 (FGFR3) - analyses of the S249C mutation and protein expression in primary cervical carcinomas
Anal Cell Pathol, 23 (2), 45-9
PubMed 11904459

Forus A, Sørlie T, Børresen-Dale AL, Myklebost O (2001)
[Microarray technology--potential in cancer research]
Tidsskr Nor Laegeforen, 121 (21), 2498-503
PubMed 11875927

Geisler S, Lønning PE, Aas T, Johnsen H, Fluge O, Haugen DF, Lillehaug JR, Akslen LA, Børresen-Dale AL (2001)
Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer
Cancer Res, 61 (6), 2505-12
PubMed 11289122

Jain AN, Chin K, Børresen-Dale AL, Erikstein BK, Eynstein Lonning P, Kaaresen R, Gray JW (2001)
Quantitative analysis of chromosomal CGH in human breast tumors associates copy number abnormalities with p53 status and patient survival
Proc Natl Acad Sci U S A, 98 (14), 7952-7
PubMed 11438741

Kristensen VN, Børresen-Dale AL, Kristensen T (2001)
Hypervariable area in the 5' flanking region of GSTP1, previously reported as a minisatellite ATAAA repeat
Hum Mutat, 17 (3), 238-9
PubMed 11241854

Kristensen VN, Harada N, Kristensen T, Borresen-Dale AL (2001)
[Genetic polymorphism and variability of steroid hormone metabolism: connection with risk of developing breast neoplasms]
Vopr Onkol, 47 (2), 156-9
PubMed 11383450

Kristensen VN, Kelefiotis D, Kristensen T, Børresen-Dale AL (2001)
High-throughput methods for detection of genetic variation
Biotechniques, 30 (2), 318-22, 324, 326 passim
PubMed 11233601

Kristensen VN, Kure EH, Erikstein B, Harada N, Børresen-Dale A (2001)
Genetic susceptibility and environmental estrogen-like compounds
Mutat Res, 482 (1-2), 77-82
PubMed 11535251

Lønning PE, Sørlie T, Perou CM, Brown PO, Botstein D, Børresen-Dale AL (2001)
Microarrays in primary breast cancer--lessons from chemotherapy studies
Endocr Relat Cancer, 8 (3), 259-63
PubMed 11566617

Olsen JH, Hahnemann JM, Børresen-Dale AL, Brøndum-Nielsen K, Hammarström L, Kleinerman R, Kääriäinen H, Lönnqvist T, Sankila R, Seersholm N, Tretli S, Yuen J, Boice JD, Tucker M (2001)
Cancer in patients with ataxia-telangiectasia and in their relatives in the nordic countries
J Natl Cancer Inst, 93 (2), 121-7
PubMed 11208881

Salahshor S, Haixin L, Huo H, Kristensen VN, Loman N, Sjöberg-Margolin S, Borg A, Børresen-Dale AL, Vorechovsky I, Lindblom A (2001)
Low frequency of E-cadherin alterations in familial breast cancer
Breast Cancer Res, 3 (3), 199-207
PubMed 11305955

Sandvik AK, Støren O, Nørsett K, Laegreid A, Børresen-Dale AL, Myklebost O (2001)
[Measurement of gene activity by DNA microarrays]
Tidsskr Nor Laegeforen, 121 (10), 1225-8
PubMed 11402749

Sørlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, Hastie T, Eisen MB, van de Rijn M, Jeffrey SS, Thorsen T, Quist H, Matese JC, Brown PO, Botstein D, Eystein Lønning P, Børresen-Dale AL (2001)
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
Proc Natl Acad Sci U S A, 98 (19), 10869-74
PubMed 11553815

Warren W, Hovig E, Smith-Sørensen B, Børresen AL, Fujimura FK, Liu Q, Feng J, Sommer SS (2001)
Detection of mutations by single-strand conformation polymorphism (SSCP) analysis and SSCP-hybrid methods
Curr Protoc Hum Genet, Chapter 7, Unit 7.4
PubMed 18428305

Publications 2000

Bukholm IK, Nesland JM, Børresen-Dale AL (2000)
Re-expression of E-cadherin, alpha-catenin and beta-catenin, but not of gamma-catenin, in metastatic tissue from breast cancer patients [seecomments]
J Pathol, 190 (1), 15-9
PubMed 10640987

Helland A, Kraggerud SM, Kristensen GB, Holm R, Abeler VM, Huebner K, Borresen-Dale AL, Lothe RA (2000)
Primary cervical carcinomas show 2 common regions of deletion at 3P, 1 within the FHIT gene: evaluation of allelic imbalance at FHIT, RB1 and TP53 in relation to survival
Int J Cancer, 88 (2), 217-22
PubMed 11004671

Hellström AC, Blegen H, Malec M, Silfverswärd C, Lystad S, Børresen-Dale AL, Auer G (2000)
Recurrent fallopian tube carcinoma: TP53 mutation and clinical course
Int J Gynecol Pathol, 19 (2), 145-51
PubMed 10782411

Hou SM, Ryberg D, Fält S, Deverill A, Tefre T, Børresen AL, Haugen A, Lambert B (2000)
GSTM1 and NAT2 polymorphisms in operable and non-operable lung cancer patients
Carcinogenesis, 21 (1), 49-54
PubMed 10607733

Jugessur A, Frost P, Andersen TI, Steine S, Lindblom A, Børresen-Dale AL, Eiken HG (2000)
Enhanced detection of mutations in BRCA1 exon 11 using restriction endonuclease fingerprinting-single-strand conformation polymorphism
J Mol Med (Berl), 78 (10), 580-7
PubMed 11199332

Kristensen VN, Borresen-Dale AL (2000)
Molecular epidemiology of breast cancer: genetic variation in steroid hormone metabolism
Mutat Res, 462 (2-3), 323-33
PubMed 10767642

Kristensen VN, Harada N, Yoshimura N, Haraldsen E, Lonning PE, Erikstein B, Kåresen R, Kristensen T, Børresen-Dale AL (2000)
Genetic variants of CYP19 (aromatase) and breast cancer risk
Oncogene, 19 (10), 1329-33
PubMed 10713674

Liestøl K, Kvittingen EA, Rootwelt H, Dunlop O, Goplen AK, Pedersen JC, Brorson SH, Børresen-Dale AL, Myrvang B, Maehlen J (2000)
Association between apolipoprotein E genotypes and cancer risk in patients with acquired immunodeficiency syndrome
Cancer Detect Prev, 24 (5), 496-9
PubMed 11129992

Laake K, Jansen L, Hahnemann JM, Brondum-Nielsen K, Lönnqvist T, Kääriäinen H, Sankila R, Lähdesmäki A, Hammarström L, Yuen J, Tretli S, Heiberg A, Olsen JH, Tucker M, Kleinerman R, Børresen-Dale AL (2000)
Characterization of ATM mutations in 41 Nordic families with ataxia telangiectasia
Hum Mutat, 16 (3), 232-46
PubMed 10980530

Laake K, Vu P, Andersen TI, Erikstein B, Kåresen R, Lonning PE, Skovlund E, Børresen-Dale AL (2000)
Screening breast cancer patients for Norwegian ATM mutations
Br J Cancer, 83 (12), 1650-3
PubMed 11104561

Perou CM, Sørlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lønning PE, Børresen-Dale AL, Brown PO, Botstein D (2000)
Molecular portraits of human breast tumours
Nature, 406 (6797), 747-52
PubMed 10963602

Stokke T, Galteland E, Holte H, Smedshammer L, Suo Z, Smeland EB, Børresen-Dale AL, DeAngelis P, Steen HB (2000)
Oncogenic aberrations in the p53 pathway are associated with a high S phase fraction and poor patient survival in B-cell Non-Hodgkin's lymphoma
Int J Cancer, 89 (4), 313-24
PubMed 10956404

Publications 1999

Arver B, Claro A, Langerød A, Børresen-Dale AL, Lindblom A (1999)
BRCA1 screening in patients with a family history of breast or ovarian cancer
Genet Test, 3 (2), 223-6
PubMed 10464672

Danielsen T, Smith-Sørensen B, Grønlund HA, Hvidsten M, Børresen-Dale AL, Rofstad EK (1999)
No association between radiosensitivity and TP53 status, G1 arrest or protein levels of p53, myc, ras or raf in human melanoma lines
Int J Radiat Biol, 75 (9), 1149-60
PubMed 10528923

Ekstrøm PO, Børresen-Dale AL, Qvist H, Giercksky KE, Thilly WG (1999)
Detection of low-frequency mutations in exon 8 of the TP53 gene by constant denaturant capillary electrophoresis (CDCE)
Biotechniques, 27 (1), 128-34
PubMed 10407675

Helland A, Børresen-Dale AL (1999)
p53 polymorphism and cervical cancer
Lancet, 354 (9189), 1561-2
PubMed 10551531

Högmo A, Börresen-Dale AL, Blegen H, Lindholm J, Kuylenstierna R, Auer G, Munck-Wikland E (1999)
TP53 mutations do not correlate with locoregional recurrence in stage I tongue carcinomas
Anticancer Res, 19 (4C), 3433-8
PubMed 10629631

Laake K, Launonen V, Niederacher D, Gudlaugsdottir S, Seitz S, Rio P, Champème MH, Bièche I, Birnbaum D, White G, Sztan M, Sever N, Plummer S, Osorio A, Broeks A, Huusko P, Spurr N, Borg A, Cleton-Jansen AM, van't Veer L, Benitez J, Casey G, Peterlin B, Olah E, Børresen-Dale AL (1999)
Loss of heterozygosity at 11q23.1 and survival in breast cancer: results of a large European study. Breast Cancer Somatic Genetics Consortium
Genes Chromosomes Cancer, 25 (3), 212-21
PubMed 10379867

Nedelcheva Kristensen V, Haraldsen EK, Anderson KB, Lønning PE, Erikstein B, Kåresen R, Gabrielsen OS, Børresen-Dale AL (1999)
CYP17 and breast cancer risk: the polymorphism in the 5' flanking area of the gene does not influence binding to Sp-1
Cancer Res, 59 (12), 2825-8
PubMed 10383140

Skomedal H, Helland A, Kristensen GB, Holm R, Børresen-Dale AL (1999)
Allelic imbalance at chromosome region 11q23 in cervical carcinomas
Eur J Cancer, 35 (4), 659-63
PubMed 10492643

Skomedal H, Kristensen GB, Nesland JM, Børresen-Dale AL, Tropé C, Holm R (1999)
TP53 alterations in relation to the cell cycle-associated proteins p21, cyclin D1, CDK4, RB, MDM2, and EGFR in cancers of the uterine corpus
J Pathol, 187 (5), 556-62
PubMed 10398121

van Slooten HJ, van De Vijver MJ, Borresen AL, Eyfjörd JE, Valgardsdóttir R, Scherneck S, Nesland JM, Devilee P, Cornelisse CJ, van Dierendonck JH (1999)
Mutations in exons 5-8 of the p53 gene, independent of their type and location, are associated with increased apoptosis and mitosis in invasive breast carcinoma
J Pathol, 189 (4), 504-13
PubMed 10629550

Publications 1998

Adélaïde J, Chaffanet M, Imbert A, Allione F, Geneix J, Popovici C, van Alewijk D, Trapman J, Zeillinger R, Børresen-Dale AL, Lidereau R, Birnbaum D, Pébusque MJ (1998)
Chromosome region 8p11-p21: refined mapping and molecular alterations in breast cancer
Genes Chromosomes Cancer, 22 (3), 186-99
PubMed 9624530

Andersen TI, Børresen-Dale AL (1998)
[Diagnostic molecular biology in breast cancer]
Tidsskr Nor Laegeforen, 118 (15), 2366-9
PubMed 9691806

Andersen TI, Eiken HG, Couch F, Kaada G, Skrede M, Johnsen H, Aloysius TA, Tveit KM, Tranebjaerg L, Dørum A, Møller P, Weber BL, Børresen-Dale AL (1998)
Constant denaturant gel electrophoresis (CDGE) in BRCA1 mutation screening
Hum Mutat, 11 (2), 166-74
PubMed 9482581

Bjørheim J, Lystad S, Lindblom A, Kressner U, Westring S, Wahlberg S, Lindmark G, Gaudernack G, Ekstrøm P, Røe J, Thilly WG, Børresen-Dale AL (1998)
Mutation analyses of KRAS exon 1 comparing three different techniques: temporal temperature gradient electrophoresis, constant denaturant capillary electrophoresis and allele specific polymerase chain reaction
Mutat Res, 403 (1-2), 103-12
PubMed 9726011

Bukholm IK, Berner JM, Nesland JM, Børresen-Dale AL (1998)
Expression of cyclin Ds in relation to p53 status in human breast carcinomas
Virchows Arch, 433 (3), 223-8
PubMed 9769125

Bukholm IK, Nesland JM, Kåresen R, Jacobsen U, Børresen-Dale AL (1998)
E-cadherin and alpha-, beta-, and gamma-catenin protein expression in relation to metastasis in human breast carcinoma
J Pathol, 185 (3), 262-6
PubMed 9771479

Børresen-Dale AL, Boman H (1998)
[Hereditary cancer]
Tidsskr Nor Laegeforen, 118 (12), 1873-7
PubMed 9638057

Børresen-Dale AL, Lothe RA, Meling GI, Hainaut P, Rognum TO, Skovlund E (1998)
TP53 and long-term prognosis in colorectal cancer: mutations in the L3 zinc-binding domain predict poor survival
Clin Cancer Res, 4 (1), 203-10
PubMed 9516972

Børresen-Dale AL, Lothe RA, Nesland JM (1998)
[Molecular biology. Basis for increased understanding of diseases and improved diagnostics]
Tidsskr Nor Laegeforen, 118 (11), 1681
PubMed 9621751

Clausen OP, Lothe RA, Børresen-Dale AL, De Angelis P, Chen Y, Rognum TO, Meling GI (1998)
Association of p53 accumulation with TP53 mutations, loss of heterozygosity at 17p13, and DNA ploidy status in 273 colorectal carcinomas
Diagn Mol Pathol, 7 (4), 215-23
PubMed 9917132

Eiken HG, Børresen-Dale AL (1998)
[Molecular genetic diagnostics. Technology for detecting mutations in DNA]
Tidsskr Nor Laegeforen, 118 (11), 1730-6
PubMed 9621763

Helland A, Karlsen F, Due EU, Holm R, Kristensen G, Børresen-Dale A (1998)
Mutations in the TP53 gene and protein expression of p53, MDM 2 and p21/WAF-1 in primary cervical carcinomas with no or low human papillomavirus load
Br J Cancer, 78 (1), 69-72
PubMed 9662253

Helland A, Langerød A, Johnsen H, Olsen AO, Skovlund E, Børresen-Dale AL (1998)
p53 polymorphism and risk of cervical cancer
Nature, 396 (6711), 530-1; author reply 532
PubMed 9859987

Helland A, Olsen AO, Gjøen K, Akselsen HE, Sauer T, Magnus P, Børresen-Dale AL, Rønningen KS (1998)
An increased risk of cervical intra-epithelial neoplasia grade II-III among human papillomavirus positive patients with the HLA-DQA1*0102-DQB1*0602 haplotype: a population-based case-control study of Norwegian women
Int J Cancer, 76 (1), 19-24
PubMed 9533756

Kressner U, Bjørheim J, Westring S, Wahlberg SS, Påhlman L, Glimelius B, Lindmark G, Lindblom A, Børresen-Dale AL (1998)
Ki-ras mutations and prognosis in colorectal cancer
Eur J Cancer, 34 (4), 518-21
PubMed 9713302

Kristensen T, Kristensen VN, Børresen-Dale AL (1998)
High-throughput screening for known mutations by automated analysis of single sequencing reactions
Biotechniques, 24 (5), 832-5
PubMed 9591134

Kristensen VN, Andersen TI, Lindblom A, Erikstein B, Magnus P, Børresen-Dale AL (1998)
A rare CYP19 (aromatase) variant may increase the risk of breast cancer
Pharmacogenetics, 8 (1), 43-8
PubMed 9511180

Lothe RA, Hektoen M, Johnsen H, Meling GI, Andersen TI, Rognum TO, Lindblom A, Børresen-Dale AL (1998)
The APC gene I1307K variant is rare in Norwegian patients with familial and sporadic colorectal or breast cancer
Cancer Res, 58 (14), 2923-4
PubMed 9679946

Laake K, Telatar M, Geitvik GA, Hansen RO, Heiberg A, Andresen AM, Gatti R, Børresen-Dale AL (1998)
Identical mutation in 55% of the ATM alleles in 11 Norwegian AT families: evidence for a founder effect
Eur J Hum Genet, 6 (3), 235-44
PubMed 9781027

Nedelcheva Kristensen V, Andersen TI, Erikstein B, Geitvik G, Skovlund E, Nesland JM, Børresen-Dale AL (1998)
Single tube multiplex polymerase chain reaction genotype analysis of GSTM1, GSTT1 and GSTP1: relation of genotypes to TP53 tumor status and clinicopathological variables in breast cancer patients
Pharmacogenetics, 8 (5), 441-7
PubMed 9825836

Phelan CM, Borg A, Cuny M, Crichton DN, Baldersson T, Andersen TI, Caligo MA, Lidereau R, Lindblom A, Seitz S, Kelsell D, Hamann U, Rio P, Thorlacius S, Papp J, Olah E, Ponder B, Bignon YJ, Scherneck S, Barkardottir R, Borresen-Dale AL, Eyfjörd J, Theillet C, Thompson AM, Larsson C (1998)
Consortium study on 1280 breast carcinomas: allelic loss on chromosome 17 targets subregions associated with family history and clinical parameters
Cancer Res, 58 (5), 1004-12
PubMed 9500463

Smith-Sørensen B, Kaern J, Holm R, Dørum A, Tropé C, Børresen-Dale AL (1998)
Therapy effect of either paclitaxel or cyclophosphamide combination treatment in patients with epithelial ovarian cancer and relation to TP53 gene status
Br J Cancer, 78 (3), 375-81
PubMed 9703286

Sørlie T, Andersen TI, Bukholm I, Børresen-Dale AL (1998)
Mutation screening of BRCA1 using PTT and LOH analysis at 17q21 in breast carcinomas from familial and non-familial cases
Breast Cancer Res Treat, 48 (3), 259-64
PubMed 9598872

Sørlie T, Bukholm I, Børresen-Dale AL (1998)
Truncating somatic mutation in exon 15 of the APC gene is a rare event in human breast carcinomas. Mutations in brief no. 179. Online
Hum Mutat, 12 (3), 215
PubMed 10660330

Sørlie T, Martel-Planche G, Hainaut P, Lewalter J, Holm R, Børresen-Dale AL, Montesano R (1998)
Analysis of p53, p16MTS, p21WAF1 and H-ras in archived bladder tumours from workers exposed to aromatic amines
Br J Cancer, 77 (10), 1573-9
PubMed 9635831

Telatar M, Teraoka S, Wang Z, Chun HH, Liang T, Castellvi-Bel S, Udar N, Borresen-Dale AL, Chessa L, Bernatowska-Matuszkiewicz E, Porras O, Watanabe M, Junker A, Concannon P, Gatti RA (1998)
Ataxia-telangiectasia: identification and detection of founder-effect mutations in the ATM gene in ethnic populations
Am J Hum Genet, 62 (1), 86-97
PubMed 9443866

Publications 1997

Anderson TI, Wooster R, Laake K, Collins N, Warren W, Skrede M, Elles R, Tveit KM, Johnston SR, Dowsett M, Olsen AO, Møller P, Stratton MR, Børresen-Dale AL (1997)
Screening for ESR mutations in breast and ovarian cancer patients
Hum Mutat, 9 (6), 531-6
PubMed 9195227

Breivik J, Lothe RA, Meling GI, Rognum TO, Børresen-Dale AL, Gaudernack G (1997)
Different genetic pathways to proximal and distal colorectal cancer influenced by sex-related factors
Int J Cancer, 74 (6), 664-9
PubMed 9421366

Bukholm IK, Nesland JM, Kåresen R, Jacobsen U, Børresen-Dale AL (1997)
Expression of E-cadherin and its relation to the p53 protein status in human breast carcinomas
Virchows Arch, 431 (5), 317-21
PubMed 9463572

Bukholm IK, Nesland JM, Kåresen R, Jacobsen U, Børresen-Dale AL (1997)
Interaction between bcl-2 and p21 (WAF1/CIP1) in breast carcinomas with wild-type p53
Int J Cancer, 73 (1), 38-41
PubMed 9334807

Bukholm IK, Nesland JM, Kåresen R, Jacobsen U, Børresen AL (1997)
Relationship between abnormal p53 protein and failure to express p21 protein in human breast carcinomas
J Pathol, 181 (2), 140-5
PubMed 9120716

Devilee P, Hermans J, Eyfjörd J, Bøorresen AL, Lidereau R, Sobol H, Borg A, Cleton-Jansen AM, Oláh E, Cohen BB, Scherneck S, Hamann U, Peterlin B, Caligo M, Bignon YJ, Maugard C (1997)
Loss of heterozygosity at 7q31 in breast cancer: results from an International Collaborative Study Group. The Breast Cancer Somatic Genetics Consortium
Genes Chromosomes Cancer, 18 (3), 193-9
PubMed 9071572

Ellis PA, Lonning PE, Borresen-Dale A, Aas T, Geisler S, Akslen LA, Salter I, Smith IE, Dowsett M (1997)
Absence of p21 expression is associated with abnormal p53 in human breast carcinomas
Br J Cancer, 76 (4), 480-5
PubMed 9275025

Heimdal K, Olsson H, Tretli S, Fosså SD, Børresen AL, Bishop DT (1997)
A segregation analysis of testicular cancer based on Norwegian and Swedish families
Br J Cancer, 75 (7), 1084-7
PubMed 9083348

Helland A, Børresen-Dale AL, Peltomäki P, Hektoen M, Kristensen GB, Nesland JM, de la Chapelle A, Lothe RA (1997)
Microsatellite instability in cervical and endometrial carcinomas
Int J Cancer, 70 (5), 499-501
PubMed 9052745

Kraggerud SM, Jacobsen KD, Berner A, Stokke T, Holm R, Smedshammer L, Børresen-Dale AL, Fosså SD (1997)
A comparison of different modes for the detection of p53 protein accumulation. A study of bladder cancer
Pathol Res Pract, 193 (7), 471-8
PubMed 9342752

Kristensen VN, Børresen-Dale AL (1997)
Improved electrophoretic separation of polymorphic short tandem repeats in agarose gels using bis-benzimide
Biotechniques, 23 (4), 634-6
PubMed 9343680

Laake K, Odegård A, Andersen TI, Bukholm IK, Kåresen R, Nesland JM, Ottestad L, Shiloh Y, Børresen-Dale AL (1997)
Loss of heterozygosity at 11q23.1 in breast carcinomas: indication for involvement of a gene distal and close to ATM
Genes Chromosomes Cancer, 18 (3), 175-80
PubMed 9071570

Paulsen T, Aas T, Børresen AL, Varhaug JE, Lønning PE, Akslen LA (1997)
Angiogenesis does not predict clinical response to doxorubicin monotherapy in patients with locally advanced breast cancer
Int J Cancer, 74 (1), 138-40
PubMed 9036883

Skomedal H, Kristensen GB, Abeler VM, Børresen-Dale AL, Tropé C, Holm R (1997)
TP53 protein accumulation and gene mutation in relation to overexpression of MDM2 protein in ovarian borderline tumours and stage I carcinomas
J Pathol, 181 (2), 158-65
PubMed 9120719

Tranebjaerg L, Børresen-Dale AL, Hansteen IL, Heim S, Kvittingen EA, Møller P (1997)
Genetic services in Norway
Eur J Hum Genet, 5 Suppl 2, 130-4
PubMed 9450210

Zelada-Hedman M, Børresen-Dale AL, Claro A, Chen J, Skoog L, Lindblom A (1997)
Screening for TP53 mutations in patients and tumours from 109 Swedish breast cancer families
Br J Cancer, 75 (8), 1201-4
PubMed 9099970

Zelada-Hedman M, Børresen-Dale AL, Lindblom A (1997)
Screening of 229 family cancer patients for a germline estrogen receptor gene (ESR) base mutation
Hum Mutat, 9 (3), 289
PubMed 9090537

Zelada-Hedman M, Wasteson Arver B, Claro A, Chen J, Werelius B, Kok H, Sandelin K, Håkansson S, Andersen TI, Borg A, Børresen Dale AL, Lindblom A (1997)
A screening for BRCA1 mutations in breast and breast-ovarian cancer families from the Stockholm region
Cancer Res, 57 (12), 2474-7
PubMed 9192828

Publications 1996

Andersen TI, Børresen AL, Møller P (1996)
A common BRCA1 mutation in Norwegian breast and ovarian cancer families?
Am J Hum Genet, 59 (2), 486-7
PubMed 8755943

Chitemerere M, Andersen TI, Holm R, Karlsen F, Børresen AL, Nesland JM (1996)
TP53 alterations in atypical ductal hyperplasia and ductal carcinoma in situ of the breast
Breast Cancer Res Treat, 41 (2), 103-9
PubMed 8944328

Heimdal K, Olsson H, Tretli S, Flodgren P, Børresen AL, Fossa SD (1996)
Familial testicular cancer in Norway and southern Sweden
Br J Cancer, 73 (7), 964-9
PubMed 8611416

Heimdal K, Olsson H, Tretli S, Flodgren P, Børresen AL, Fossa SD (1996)
Risk of cancer in relatives of testicular cancer patients
Br J Cancer, 73 (7), 970-3
PubMed 8611417

Lothe RA, Karhu R, Mandahl N, Mertens F, Saeter G, Heim S, Borresen-Dale AL, Kallioniemi OP (1996)
Gain of 17q24-qter detected by comparative genomic hybridization in malignant tumors from patients with von Recklinghausen's neurofibromatosis
Cancer Res, 56 (20), 4778-81
PubMed 8840998

Maelandsmo GM, Flørenes VA, Hovig E, Oyjord T, Engebraaten O, Holm R, Børresen AL, Fodstad O (1996)
Involvement of the pRb/p16/cdk4/cyclin D1 pathway in the tumorigenesis of sporadic malignant melanomas
Br J Cancer, 73 (8), 909-16
PubMed 8611425

Zedenius J, Larsson C, Wallin G, Bäckdahl M, Aspenblad U, Höög A, Børresen AL, Auer G (1996)
Alterations of p53 and expression of WAF1/p21 in human thyroid tumors
Thyroid, 6 (1), 1-9
PubMed 8777377

Aas T, Børresen AL, Geisler S, Smith-Sørensen B, Johnsen H, Varhaug JE, Akslen LA, Lønning PE (1996)
Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients
Nat Med, 2 (7), 811-4
PubMed 8673929

Aas T, Geisler S, Paulsen T, Børresen-Dale AL, Varhaug JE, Lønning PE, Akslen LA (1996)
Primary systemic treatment with weekly doxorubicin monotherapy in women with locally advanced breast cancer; clinical experience and parameters predicting outcome
Acta Oncol, 35 Suppl 5, 5-8
PubMed 9142957

Publications 1995

Andersen TI, Børresen AL (1995)
Alterations of the TP53 gene as a potential prognostic marker in breast carcinomas. Advantages of using constant denaturant gel electrophoresis in mutation detection
Diagn Mol Pathol, 4 (3), 203-11
PubMed 7493140

Andersen TI, Paus E, Nesland JM, McKenzie SJ, Børresen AL (1995)
Detection of c-erbB-2 related protein in sera from breast cancer patients. Relationship to ERBB2 gene amplification and c-erbB-2 protein overexpression in tumour
Acta Oncol, 34 (4), 499-504
PubMed 7605658

Berner A, Geitvik G, Karlsen F, Fosså SD, Nesland JM, Børresen AL (1995)
TP53 mutations in prostatic cancer. Analysis of pre- and post-treatment archival formalin-fixed tumour tissue
J Pathol, 176 (3), 299-308
PubMed 7674092

Børresen AL, Andersen TI, Eyfjörd JE, Cornelis RS, Thorlacius S, Borg A, Johansson U, Theillet C, Scherneck S, Hartman S (1995)
TP53 mutations and breast cancer prognosis: particularly poor survival rates for cases with mutations in the zinc-binding domains
Genes Chromosomes Cancer, 14 (1), 71-5
PubMed 8527388

Børresen AL, Lothe RA, Meling GI, Lystad S, Morrison P, Lipford J, Kane MF, Rognum TO, Kolodner RD (1995)
Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas
Hum Mol Genet, 4 (11), 2065-72
PubMed 8589682

Friend S, Borresen AL, Brody L, Casey G, Devilee P, Gayther S, Goldgar D, Murphy P, Weber BL, Wiseman R (1995)
Breast cancer information on the web
Nat Genet, 11 (3), 238-9
PubMed 7581445

Heimdal K, Andersen TI, Skrede M, Fosså SD, Berg K, Børresen AL (1995)
Association studies of estrogen receptor polymorphisms in a Norwegian testicular cancer population
Cancer Epidemiol Biomarkers Prev, 4 (2), 123-6
PubMed 7742719

Lange E, Borresen AL, Chen X, Chessa L, Chiplunkar S, Concannon P, Dandekar S, Gerken S, Lange K, Liang T (1995)
Localization of an ataxia-telangiectasia gene to an approximately 500-kb interval on chromosome 11q23.1: linkage analysis of 176 families by an international consortium
Am J Hum Genet, 57 (1), 112-9
PubMed 7611279

Lothe RA, Andersen SN, Hofstad B, Meling GI, Peltomäki P, Heim S, Brøgger A, Vatn M, Rognum TO, Børresen AL (1995)
Deletion of 1p loci and microsatellite instability in colorectal polyps
Genes Chromosomes Cancer, 14 (3), 182-8
PubMed 8589034

Lothe RA, Børresen AL (1995)
[Early diagnosis of colorectal tumors]
Tidsskr Nor Laegeforen, 115 (26), 3231-2
PubMed 7482447

Lothe RA, Peltomäki P, Tommerup N, Fosså SD, Stenwig AE, Børresen AL, Nesland JM (1995)
Molecular genetic changes in human male germ cell tumors
Lab Invest, 73 (5), 606-14
PubMed 7474934

Lothe RA, Slettan A, Saeter G, Brøgger A, Børresen AL, Nesland JM (1995)
Alterations at chromosome 17 loci in peripheral nerve sheath tumors
J Neuropathol Exp Neurol, 54 (1), 65-73
PubMed 7815081

Skomedal H, Kristensen G, Helland A, Nesland JM, Kooi S, Børresen AL, Holm R (1995)
TP53 gene mutations and protein accumulation in primary vaginal carcinomas
Br J Cancer, 72 (1), 129-33
PubMed 7599041

Steen VM, Andreassen OA, Daly AK, Tefre T, Børresen AL, Idle JR, Gulbrandsen AK (1995)
Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology
Pharmacogenetics, 5 (4), 215-23
PubMed 8528268

Thorlacius S, Thorgilsson B, Björnsson J, Tryggvadottir L, Börresen AL, Ogmundsdottir HM, Eyfjörd JE (1995)
TP53 mutations and abnormal p53 protein staining in breast carcinomas related to prognosis
Eur J Cancer, 31A (11), 1856-61
PubMed 8541113

Publications 1994

Andersen TI, Heimdal KR, Skrede M, Tveit K, Berg K, Børresen AL (1994)
Oestrogen receptor (ESR) polymorphisms and breast cancer susceptibility
Hum Genet, 94 (6), 665-70
PubMed 7989041

Cornelis RS, van Vliet M, Vos CB, Cleton-Jansen AM, van de Vijver MJ, Peterse JL, Khan PM, Børresen AL, Cornelisse CJ, Devilee P (1994)
Evidence for a gene on 17p13.3, distal to TP53, as a target for allele loss in breast tumors without p53 mutations
Cancer Res, 54 (15), 4200-6
PubMed 8033152

Flørenes VA, Oyjord T, Holm R, Skrede M, Børresen AL, Nesland JM, Fodstad O (1994)
TP53 allele loss, mutations and expression in malignant melanoma
Br J Cancer, 69 (2), 253-9
PubMed 7905277

Gatti RA, Lange E, Rotman G, Chen X, Uhrhammer N, Liang T, Chiplunkar S, Yang L, Udar N, Dandekar S, Sheikhavandi S, Wang Z, Yang HM, Polikow J, Elashoff M, Teletar M, Sanal O, Chessa L, McConville C, Taylor M, Shiloh Y, Porras O, Borresen AL, Wegner RD, Curry C et al. (1994)
Genetic haplotyping of ataxia-telangiectasia families localizes the major gene to an approximately 850 kb region on chromosome 11q23.1
Int J Radiat Biol, 66 (6 Suppl), S57-62
PubMed 7836853

Heimdal KR, Lothe RA, Fosså SD, Børresen AL (1994)
Association studies of a polymorphism in the Wilms' tumor 1 locus in Norwegian patients with testicular cancer
Int J Cancer, 58 (4), 523-6
PubMed 8056449

Helland A, Børresen AL, Kristensen G, Rønningen KS (1994)
DQA1 and DQB1 genes in patients with squamous cell carcinoma of the cervix: relationship to human papillomavirus infection and prognosis
Cancer Epidemiol Biomarkers Prev, 3 (6), 479-86
PubMed 8000298

McIntyre JF, Smith-Sorensen B, Friend SH, Kassell J, Borresen AL, Yan YX, Russo C, Sato J, Barbier N, Miser J (1994)
Germline mutations of the p53 tumor suppressor gene in children with osteosarcoma
J Clin Oncol, 12 (5), 925-30
PubMed 8164043

Nesland JM, Børresen AL, Andersson LC (1994)
[Molecular pathology. A new diagnostic dimension]
Tidsskr Nor Laegeforen, 114 (26), 3047-8
PubMed 7974419

Rosenberg C, Andersen TI, Nesland JM, Lier ME, Brøgger A, Børresen AL (1994)
Genetic alterations of chromosome 17 in human breast carcinoma studied by fluorescence in situ hybridization and molecular DNA techniques
Cancer Genet Cytogenet, 75 (1), 1-5
PubMed 8039157

Rosenberg C, Janson M, Nordeskjöld M, Børresen AL, Vianna-Morgante AM (1994)
Intragenic reorganization of RB1 in a complex (4;13) rearrangement demonstrated by FISH
Cytogenet Cell Genet, 65 (4), 268-71
PubMed 8258302

Ryberg D, Kure E, Lystad S, Skaug V, Stangeland L, Mercy I, Børresen AL, Haugen A (1994)
p53 mutations in lung tumors: relationship to putative susceptibility markers for cancer
Cancer Res, 54 (6), 1551-5
PubMed 8137262

Seruca R, David L, Castedo S, Veiga I, Børresen AL, Sobrinho-Simões M (1994)
p53 alterations in gastric carcinoma: a study of 56 primary tumors and 204 nodal metastases
Cancer Genet Cytogenet, 75 (1), 45-50
PubMed 8039163

Tefre T, Daly AK, Armstrong M, Leathart JB, Idle JR, Brøgger A, Børresen AL (1994)
Genotyping of the CYP2D6 gene in Norwegian lung cancer patients and controls
Pharmacogenetics, 4 (2), 47-57
PubMed 8081413

Verwest AM, de Leeuw WJ, Molijn AC, Andersen TI, Börresen AL, Mullaart E, Uitterlinden AG, Vijg J (1994)
Genome scanning of breast cancers by two-dimensional DNA typing
Br J Cancer, 69 (1), 84-92
PubMed 8286216

Publications 1993

Andersen TI, Holm R, Nesland JM, Heimdal KR, Ottestad L, Børresen AL (1993)
Prognostic significance of TP53 alterations in breast carcinoma
Br J Cancer, 68 (3), 540-8
PubMed 8102535

Andreassen A, Oyjord T, Hovig E, Holm R, Flørenes VA, Nesland JM, Myklebost O, Høie J, Bruland OS, Børresen AL (1993)
p53 abnormalities in different subtypes of human sarcomas
Cancer Res, 53 (3), 468-71
PubMed 8425179

Børresen AL (1993)
[The 1993 Nobel Prize in chemistry--polymerase chain reaction and directed mutagenesis]
Tidsskr Nor Laegeforen, 113 (30), 3668-9
PubMed 8278946

Condie A, Eeles R, Borresen AL, Coles C, Cooper C, Prosser J (1993)
Detection of point mutations in the p53 gene: comparison of single-strand conformation polymorphism, constant denaturant gel electrophoresis, and hydroxylamine and osmium tetroxide techniques
Hum Mutat, 2 (1), 58-66
PubMed 8477265

Heimdal K, Lothe RA, Lystad S, Holm R, Fosså SD, Børresen AL (1993)
No germline TP53 mutations detected in familial and bilateral testicular cancer
Genes Chromosomes Cancer, 6 (2), 92-7
PubMed 7680893

Helland A, Holm R, Kristensen G, Kaern J, Karlsen F, Trope C, Nesland JM, Børresen AL (1993)
Genetic alterations of the TP53 gene, p53 protein expression and HPV infection in primary cervical carcinomas
J Pathol, 171 (2), 105-14
PubMed 8283348

Holm R, Skomedal H, Helland A, Kristensen G, Børresen AL, Nesland JM (1993)
Immunohistochemical analysis of p53 protein overexpression in normal, premalignant, and malignant tissues of the cervix uteri
J Pathol, 169 (1), 21-6
PubMed 8433212

Hovig E, Mullaart E, Børresen AL, Uitterlinden AG, Vijg J (1993)
Genome scanning of human breast carcinomas using micro- and minisatellite core probes
Genomics, 17 (1), 66-75
PubMed 8104870

Lothe RA, Hastie N, Heimdal K, Fosså SD, Stenwig AE, Børresen AL (1993)
Frequent loss of 11p13 and 11p15 loci in male germ cell tumours
Genes Chromosomes Cancer, 7 (2), 96-101
PubMed 7687459

Lothe RA, Saeter G, Danielsen HE, Stenwig AE, Høyheim B, O'Connell P, Børresen AL (1993)
Genetic alterations in a malignant schwannoma from a patient with neurofibromatosis (NF1)
Pathol Res Pract, 189 (4), 465-71; discussion 471-4
PubMed 8351250

Meling GI, Lothe RA, Børresen AL, Graue C, Hauge S, Clausen OP, Rognum TO (1993)
The TP53 tumour suppressor gene in colorectal carcinomas. II. Relation to DNA ploidy pattern and clinicopathological variables
Br J Cancer, 67 (1), 93-8
PubMed 8427784

Meling GI, Lothe RA, Børresen AL, Graue C, Hauge S, Clausen OP, Rognum TO (1993)
The TP53 tumour suppressor gene in colorectal carcinomas. I. Genetic alterations on chromosome 17
Br J Cancer, 67 (1), 88-92
PubMed 8094008

Ottestad L, Andersen TI, Nesland JM, Skrede M, Tveit KM, Nustad K, Børresen AL (1993)
Amplification of c-erbB-2, int-2 and c-myc genes in node-negative breast carcinomas. Relationship to prognosis
Acta Oncol, 32 (3), 289-94
PubMed 8100712

Ridanpää M, Lothe RA, Onfelt A, Fosså S, Børresen AL, Husgafvel-Pursiainen K (1993)
K-ras oncogene codon 12 point mutations in testicular cancer
Environ Health Perspect, 101 Suppl 3, 185-7
PubMed 8143614

Ryberg D, Heimdal K, Fosså SD, Børresen AL, Haugen A (1993)
Rare Ha-ras1 alleles and predisposition to testicular cancer
Int J Cancer, 53 (6), 938-40
PubMed 8097187

Smith-Sørensen B, Gebhardt MC, Kloen P, McIntyre J, Aguilar F, Cerutti P, Børresen AL (1993)
Screening for TP53 mutations in osteosarcomas using constant denaturant gel electrophoresis (CDGE)
Hum Mutat, 2 (4), 274-85
PubMed 8401536

Thorlacius S, Börresen AL, Eyfjörd JE (1993)
Somatic p53 mutations in human breast carcinomas in an Icelandic population: a prognostic factor
Cancer Res, 53 (7), 1637-41
PubMed 8453635

Publications 1992

Andersen TI, Gaustad A, Ottestad L, Farrants GW, Nesland JM, Tveit KM, Børresen AL (1992)
Genetic alterations of the tumour suppressor gene regions 3p, 11p, 13q, 17p, and 17q in human breast carcinomas
Genes Chromosomes Cancer, 4 (2), 113-21
PubMed 1373310

Børresen AL (1992)
Role of genetic factors in breast cancer susceptibility
Acta Oncol, 31 (2), 151-5
PubMed 1622629

Børresen AL (1992)
Oncogenesis in ovarian cancer
Acta Obstet Gynecol Scand Suppl, 155, 25-30
PubMed 1502889

Børresen AL, Andersen TI, Garber J, Barbier-Piraux N, Thorlacius S, Eyfjörd J, Ottestad L, Smith-Sørensen B, Hovig E, Malkin D (1992)
Screening for germ line TP53 mutations in breast cancer patients
Cancer Res, 52 (11), 3234-6
PubMed 1591732

Børresen AL, Helland A, Nesland J, Holm R, Trope C, Kaern J (1992)
Papillomaviruses, p53, and cervical cancer
Lancet, 339 (8805), 1350-1
PubMed 1350005

David L, Seruca R, Nesland JM, Soares P, Sansonetty F, Holm R, Børresen AL, Sobrinho-Simões M (1992)
c-erbB-2 expression in primary gastric carcinomas and their metastases
Mod Pathol, 5 (4), 384-90
PubMed 1353880

Frebourg T, Kassel J, Lam KT, Gryka MA, Barbier N, Andersen TI, Børresen AL, Friend SH (1992)
Germ-line mutations of the p53 tumor suppressor gene in patients with high risk for cancer inactivate the p53 protein
Proc Natl Acad Sci U S A, 89 (14), 6413-7
PubMed 1631137

Helland A, Børresen AL, Kaern J, Rønningen KS, Thorsby E (1992)
HLA antigens and cervical carcinoma
Nature, 356 (6364), 23
PubMed 1538776

Hovig E, Andreassen A, Fangan BM, Børresen AL (1992)
A TP53 mutation detected in cells established from an osteosarcoma, but not in the retinoblastoma of a patient with bilateral retinoblastoma and multiple primary osteosarcomas
Cancer Genet Cytogenet, 64 (2), 178-82
PubMed 1336709

Hovig E, Smith-Sørensen B, Gebhardt MC, Ryberg D, Lothe R, Børresen AL (1992)
No alterations in exon 21 of the RB1 gene in sarcomas and carcinomas of the breast, colon, and lung
Genes Chromosomes Cancer, 5 (2), 97-103
PubMed 1381957

Hovig E, Smith-Sørensen B, Uitterlinden AG, Børresen AL (1992)
Detection of DNA variation in cancer
Pharmacogenetics, 2 (6), 317-28
PubMed 1306133

Husgafvel-Pursiainen K, Ridanpää M, Hackman P, Anttila S, Karjalainen A, Onfelt A, Børresen AL, Vainio H (1992)
Detection of ras gene mutations in human lung cancer: comparison of two screening assays based on the polymerase chain reaction
Environ Health Perspect, 98, 183-5
PubMed 1486847

Lothe RA, Fossli T, Danielsen HE, Stenwig AE, Nesland JM, Gallie B, Børresen AL (1992)
Molecular genetic studies of tumor suppressor gene regions on chromosomes 13 and 17 in colorectal tumors
J Natl Cancer Inst, 84 (14), 1100-8
PubMed 1619684

Malkin D, Jolly KW, Barbier N, Look AT, Friend SH, Gebhardt MC, Andersen TI, Børresen AL, Li FP, Garber J (1992)
Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms
N Engl J Med, 326 (20), 1309-15
PubMed 1565144

Peltomäki P, Lothe RA, Børresen AL, Fosså SD, Brøgger A, de la Chapelle A (1992)
Chromosome 12 in human testicular cancer: dosage changes and their parental origin
Cancer Genet Cytogenet, 64 (1), 21-6
PubMed 1458445

Ryberg D, Tefre T, Skaug V, Stangeland L, Ovrebø S, Naalsund A, Børresen AL, Haugen A (1992)
Allele diversity of the H-ras-1 variable number of tandem repeats in Norwegian lung cancer patients
Environ Health Perspect, 98, 187-9
PubMed 1362538

Seruca R, David L, Holm R, Nesland JM, Fangan BM, Castedo S, Sobrinho-Simões M, Børresen AL (1992)
P53 mutations in gastric carcinomas
Br J Cancer, 65 (5), 708-10
PubMed 1586599

Smith-Sørensen B, Hovig E, Andersson B, Børresen AL (1992)
Screening for mutations in human HPRT cDNA using the polymerase chain reaction (PCR) in combination with constant denaturant gel electrophoresis (CDGE)
Mutat Res, 269 (1), 41-53
PubMed 1381470

Publications 1991

Børresen AL, Hovig E, Smith-Sørensen B, Malkin D, Lystad S, Andersen TI, Nesland JM, Isselbacher KJ, Friend SH (1991)
Constant denaturant gel electrophoresis as a rapid screening technique for p53 mutations
Proc Natl Acad Sci U S A, 88 (19), 8405-9
PubMed 1924299

Hovig, Eivind, Smith-Sørensen B, Brøgger A, Børrensen AL (1991)
Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection
Mutat Res, 263 (1), 61
PubMed 2034242

Hovig E, Lothe R, Farrants G, Brøgger A, Fodstad O, Børresen AL (1991)
Chromosome 13 alterations in osteosarcoma cell lines derived from a patient with previous retinoblastoma
Cancer Genet Cytogenet, 57 (1), 31-40
PubMed 1684533

Hovig E, Smith-Sørensen B, Brøgger A, Børresen AL (1991)
Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection
Mutat Res, 262 (1), 63-71
PubMed 1702518

Meling GI, Lothe RA, Børresen AL, Hauge S, Graue C, Clausen OP, Rognum TO (1991)
Genetic alterations within the retinoblastoma locus in colorectal carcinomas. Relation to DNA ploidy pattern studied by flow cytometric analysis
Br J Cancer, 64 (3), 475-80
PubMed 1911187

Nesland JM, Ottestad L, Børresen AL, Tvedt KE, Holm R, Heikkilä R, Tveit K (1991)
The c-erbB-2 protein in primary and metastatic breast carcinomas
Ultrastruct Pathol, 15 (3), 281-9
PubMed 1678562

Nesland JM, Ottestad L, Heikilla R, Holm R, Tveit K, Børresen AL (1991)
C-erbB-2 protein and neuroendocrine expression in breast carcinomas
Anticancer Res, 11 (1), 161-7
PubMed 1673329

Peltomäki P, Lothe R, Børresen AL, Fosså SD, Brøgger A, de la Chapelle A (1991)
Altered dosage of the sex chromosomes in human testicular cancer: a molecular genetic study
Int J Cancer, 47 (4), 518-22
PubMed 1995482

Tefre T, Ryberg D, Haugen A, Nebert DW, Skaug V, Brøgger A, Børresen AL (1991)
Human CYP1A1 (cytochrome P(1)450) gene: lack of association between the Msp I restriction fragment length polymorphism and incidence of lung cancer in a Norwegian population
Pharmacogenetics, 1 (1), 20-5
PubMed 1726950

Publications 1990

BORRESEN A (1990)
THE USE OF GENE TECHNOLOGY IN THE CLINICAL LABORATORY
Scand. J. Clin. Lab. Invest., 50 202, 9-13

Børresen AL (1990)
The use of gene technology in the clinical laboratory
Scand J Clin Lab Invest Suppl, 202, 9-13
PubMed 2075459

Børresen AL, Andersen TI, Tretli S, Heiberg A, Møller P (1990)
Breast cancer and other cancers in Norwegian families with ataxia-telangiectasia
Genes Chromosomes Cancer, 2 (4), 339-40
PubMed 2268581

Børresen AL, Hovig E, Smith-Sørensen B, Vrieling H, Apold J, Brøgger A (1990)
Screening for base mutations in the PAH and HPRT loci using the polymerase chain reaction (PCR) in combination with denaturing gradient gel electrophoresis (DGGE)
Prog Clin Biol Res, 340A, 389-98
PubMed 2388921

Børresen AL, Ottestad L, Gaustad A, Andersen TI, Heikkilä R, Jahnsen T, Tveit KM, Nesland JM (1990)
Amplification and protein over-expression of the neu/HER-2/c-erbB-2 protooncogene in human breast carcinomas: relationship to loss of gene sequences on chromosome 17, family history and prognosis
Br J Cancer, 62 (4), 585-90
PubMed 1977466

Fosså SD, Langmark F, Aass N, Andersen A, Lothe R, Børresen AL (1990)
Second non-germ cell malignancies after radiotherapy of testicular cancer with or without chemotherapy
Br J Cancer, 61 (4), 639-43
PubMed 2109999

Haugen A, Willey J, Børresen AL, Tefre T (1990)
PstI polymorphism at the human P1450 gene on chromosome 15
Nucleic Acids Res, 18 (10), 3114
PubMed 1971943

Møller P, Moe N, Saugstad OD, Skullerud K, Velken M, Berg K, Nitter-Hauge S, Børresen AL (1990)
Spinal muscular atrophy type I combined with atrial septal defect in three sibs
Clin Genet, 38 (2), 81-3
PubMed 2208769

Ryberg D, Tefre T, Ovrebø S, Skaug V, Stangeland L, Naalsund A, Baera R, Børresen AL, Haugen A (1990)
Ha-ras-1 alleles in Norwegian lung cancer patients
Hum Genet, 86 (1), 40-4
PubMed 1979305

Tefre T, Børresen AL, Aamdal S, Brøgger A (1990)
Studies of the L-myc DNA polymorphism and relation to metastasis in Norwegian lung cancer patients
Br J Cancer, 61 (6), 809-12
PubMed 1973618

Publications 1989

Børresen AL (1989)
[Gene technology in clinical medicine--technics and tools]
Tidsskr Nor Laegeforen, 109 (28), 2882-7
PubMed 2815027

Børresen AL, Berg K (1989)
[Genetic variation and genetic diseases]
Tidsskr Nor Laegeforen, 109 (29), 3003-9
PubMed 2588229

Børresen AL, Brøgger A, Møller P, Smeland E (1989)
[Gene technology in the prevention of cancer]
Tidsskr Nor Laegeforen, 109 (33), 3430-4
PubMed 2609305

Lothe RA, Fosså SD, Stenwig AE, Nakamura Y, White R, Børresen AL, Brøgger A (1989)
Loss of 3p or 11p alleles is associated with testicular cancer tumors
Genomics, 5 (1), 134-8
PubMed 2767683

Publications 1988

Børresen AL, Boman H, Møller P, Berg K (1988)
Prenatal diagnosis in a female carrying a deletion close to the Duchenne locus
Prenat Diagn, 8 (1), 67-72
PubMed 3422736

Børresen AL, Hovig E, Brøgger A (1988)
Detection of base mutations in genomic DNA using denaturing gradient gel electrophoresis (DGGE) followed by transfer and hybridization with gene-specific probes
Mutat Res, 202 (1), 77-83
PubMed 2903443

Børresen AL, Møller P, Berg K (1988)
Linkage disequilibrium analyses and restriction mapping of four RFLPs at the pro alpha 2(I) collagen locus: lack of correlation between linkage disequilibrium and physical distance
Hum Genet, 78 (3), 216-21
PubMed 2894343

Publications 1987

Børresen AL, Heiberg A, Møller P, Berg K (1987)
Evidence for a sperm mutation resulting in Duchenne muscular dystrophy
Clin Genet, 32 (3), 187-91
PubMed 2887319

Børresen AL, Hellerud C, Møller P, Søvik O, Berg K (1987)
Prenatal diagnosis of glycerol-kinase deficiency associated with a DNA deletion on the short arm of the X-chromosome
Clin Genet, 32 (4), 254-9
PubMed 2890456

Børresen AL, Leren T, Berg K, Solaas MH (1987)
Effect of haptoglobin subtypes on serum lipid levels
Hum Hered, 37 (3), 150-6
PubMed 3583295

Rivrud GN, Hagen I, Børresen AL (1987)
Mutagenicity testing of human milk from smokers and non-smokers in the Salmonella/microsome test
Life Sci, 41 (21), 2389-96
PubMed 3316890

Skjørten F, Bakken J, Halvorsen S, Børresen AL (1987)
[Fabry's disease detected by renal biopsy]
Tidsskr Nor Laegeforen, 107 (9), 848, 873
PubMed 3109070

Publications 1986

Børresen AL (1986)
RFLPs in collagen loci and disease
Ann Clin Res, 18 (5-6), 258-63
PubMed 2882728

Dahl LB, Dahl IM, Børresen AL (1986)
The molecular weight of sodium hyaluronate in amniotic fluid
Biochem Med Metab Biol, 35 (2), 219-26
PubMed 3707753

Tsipouras P, Børresen AL, Bamforth S, Harper PS, Berg K (1986)
Marfan syndrome: exclusion of genetic linkage to the COL1A2 gene
Clin Genet, 30 (5), 428-32
PubMed 2879657

Publications 1985

Børresen AL, Berg K, Tsipouras P, Dickson LA, Prockop DJ, Ramirez F (1985)
DNA polymorphisms in collagen genes: potential use in the study of disease
Prog Clin Biol Res, 177, 37-51
PubMed 2989837

Børresen AL, Jordfald AB, Berg K (1985)
DNA polymorphism of the RC8 probe on the X-chromosome. Identification of a new DNA variant with the TaqI enzyme
Clin Genet, 27 (4), 411-3
PubMed 2986884

Kvittingen EA, Børresen AL, Stokke O, van der Hagen CB, Lie SO (1985)
Deficiency of fumarylacetoacetase without hereditary tyrosinemia
Clin Genet, 27 (6), 550-4
PubMed 4017276

Kvittingen EA, Steinmann B, Gitzelmann R, Leonard JV, Andria G, Børresen AL, Mossman J, Micara G, Lindblad B (1985)
Prenatal diagnosis of hereditary tyrosinemia by determination of fumarylacetoacetase in cultured amniotic fluid cells
Pediatr Res, 19 (4), 334-7
PubMed 4000758

Leren TP, Børresen AL, Berg K, Hjermann I, Leren P (1985)
Increased frequency of the apolipoprotein E-4 isoform in male subjects with multifactorial hypercholesterolemia
Clin Genet, 27 (5), 458-62
PubMed 4006269

Leren TP, Hjermann I, Børresen AL, Berg K, Leren P (1985)
Maximal low density lipoprotein receptor activity and the effect of lipid lowering diet on total serum cholesterol
Clin Genet, 27 (6), 543-9
PubMed 4017275

Publications 1984

Humphries SE, Berg K, Gill L, Cumming AM, Robertson FW, Stalenhoef AF, Williamson R, Børresen AL (1984)
The gene for apolipoprotein C-II is closely linked to the gene for apolipo-protein E on chromosome 19
Clin Genet, 26 (5), 389-96
PubMed 6094053

Magnus P, Børresen AL, Opstad PK, Bugge JF, Berg K (1984)
Increase in the ratio of serum levels of apolipoproteins A-I and A-II during prolonged physical strain and calorie deficiency
Eur J Appl Physiol Occup Physiol, 53 (1), 21-4
PubMed 6439559

Marhaug G, Børresen AL, Husby G, Nordstoga K (1984)
A comparative study of serum amyloid a protein (SAA) from mink and man
Comp Biochem Physiol B, 78 (2), 401-6
PubMed 6467904

Tsipouras P, Børresen AL, Dickson LA, Berg K, Prockop DJ, Ramirez F (1984)
Molecular heterogeneity in the mild autosomal dominant forms of osteogenesis imperfecta
Am J Hum Genet, 36 (6), 1172-9
PubMed 6097110

Ziesler O, Hole K, Haugan I, Børresen AL, Gjessing LR, Sjaastad O (1984)
Transport and distribution of homocarnosine after intracerebroventricular and intravenous injection in the rat
Neurochem Res, 9 (5), 637-48
PubMed 6472567

Publications 1982

Børresen AL, Maartmann-Moe K, Berg K (1982)
Serum reserve cholesterol binding capacity (SRCBC) in familial hypercholesterolemia
Clin Genet, 21 (6), 362-5
PubMed 6813000

Fowler B, Børresen AL, Boman N (1982)
Prenatal diagnosis of homocystinuria
Lancet, 2 (8303), 875
PubMed 6126732

Publications 1981

Berg K, Børresen AL, Nance WE (1981)
Apparent influence of marker genotypes on variation in serum cholesterol in monozygotic twins
Clin Genet, 19 (1), 67-70
PubMed 6936104

Børresen AL, Berg K (1981)
The apoE polymorphism studied by two-dimensional, high-resolution gel electrophoresis of serum
Clin Genet, 20 (6), 438-48
PubMed 7199983

Børresen AL, Berg K (1981)
Serum reserve cholesterol binding capacity (SRCBC): the relative importance of different lipoprotein classes
Artery, 9 (2), 96-119
PubMed 6794547

Børresen AL, Berg K, Dahlén G, Gillnäs T, Ericson C (1981)
The effect of Gemfibrozil on human serum apolipoproteins and on serum reserve cholesterol binding capacity (SRCBC)
Artery, 9 (1), 77-86
PubMed 7018466

Børresen AL, Berg K, Magnus P (1981)
A twin study of aryl hydrocarbon hydroxylase (AHH) inducibility in cultured lymphocytes
Clin Genet, 19 (4), 281-9
PubMed 6944164

Maartmann-Moe K, Magnus P, Børresen AL, Berg K (1981)
Low density lipoprotein receptor activity in cultured fibroblasts from subjects with or without ischemic heart disease (in the absence of familial hypercholesterolemia)
Clin Genet, 20 (5), 337-46
PubMed 6277536

Publications 1980

Børresen AL, Berg K (1980)
Presence of "free" apoA-I in serum: implications for immunological quantification of HDL and its apoproteins
Artery, 7 (2), 139-60
PubMed 7425861

Dahlén G, Gillnäs T, Børresen AL, Berg K, Ericson C (1980)
Effect of gemfibrozil on serum lipid levels
Artery, 7 (3), 224-31
PubMed 7008748

Skogen B, Natvig JB, Bøorresen AL, Berg K (1980)
Degradation of amyloid-related serum protein SAA by a component present in rabbit and human serum
Scand J Immunol, 11 (6), 643-8
PubMed 6777866

Publications 1979

Berg K, Börresen AL, Dahlen G (1979)
Effect of smoking on serum levels of HDL apoproteins
Atherosclerosis, 34 (3), 339-43
PubMed 229876

Berg K, Dahlén G, Børresen AL (1979)
Lp(a) phenotypes, other lipoprotein parameters, and a family history of coronary heart disease in middle-aged males
Clin Genet, 16 (5), 347-52
PubMed 230000

Skogen B, Børresen AL, Natvig JB, Berg K, Michaelsen TE (1979)
High-density lipoprotein as carrier for amyloid-related protein SAA in rabbit serum
Scand J Immunol, 10 (1), 39-45
PubMed 224449

Publications 1978

Børresen AL (1978)
The distribution of the inherited Hl 1 and R 67 antigens on rabbit serum high density lipoprotein (HDL) particles
J Immunogenet, 5 (1), 13-23
PubMed 205613

Børresen AL, Kindt TJ (1978)
Purification and partial characterization of the apoA-I of rabbit high density lipoprotein
J Immunogenet, 5 (1), 5-12
PubMed 205614

Børresen AL, Kindt TJ, Berg K (1978)
Partial purification and characterization of the inherited Hl 1 and R 67 antigens of rabbit serum high density lipoprotein
J Immunogenet, 5 (2), 71-86
PubMed 207781

Publications 1977

Borresen AL (1977)
High densitiy lipoprotein (HDL) polymorphisms in rabbit: production of antibody to rabbit allotype (R 67) in sheep
J Immunogenet, 4 (3), 149-58
PubMed 197172

Borresen AL, Berg K, Kindt TJ (1977)
A linkage study of rabbit serum high density lipoprotein (HDL) allotypes
J Immunogenet, 4 (2), 81-95
PubMed 194985

Publications 1976

Berg K, Borresen AL (1976)
Serum-high-density-lipoprotein and atherosclerotic heart-disease
Lancet, 1 (7958), 499-501
PubMed 55778

Berg K, Borresen AL, Frick MH, Dahlén G, Stene J (1976)
Letter: Serum-H.D.L. in a therosclerotic heart-disease
Lancet, 2 (7975), 40-1
PubMed 59096

Borresen AL (1976)
High density lipoprotein (HDL) polymorphisms in rabbit. III. Quantitative determination of HDL and the inherited Hl 1 and R 67 antigens
J Immunogenet, 3 (2), 91-103
PubMed 58950

Borresen AL (1976)
High density lipoprotein (HDL) polymorphisms in rabbit. I. A comparative study of rabbit and human serum high density lipoprotein
J Immunogenet, 3 (2), 73-81
PubMed 180184

Borresen AL (1976)
Letter: Prenatal metachromatic leukodystrophy
Helv Paediatr Acta, 30 (6), 553
PubMed 1270328

Borresen AL (1976)
High density lipoprotein (HDL) polymorphisms in rabbit. II. A study of the inherited Hl 1 and R 67 antigens in relation to HDL polypeptides
J Immunogenet, 3 (2), 83-9
PubMed 58949

Publications 1973

Borresen AL, van der Hagen CB (1973)
Metachromatic leukodystrophy. II. Direct determination of arylsulphatase A activity in amniotic fluid
Clin Genet, 4 (5), 442-6
PubMed 4751314

van der Hagen CB, Borresen AL, Molne K, Oftedal G, Bjoro K, Berg K (1973)
Metachromatic leukodystrophy. I. Prenatal detection of arylsulphatase A deficiency
Clin Genet, 4 (3), 256-9
PubMed 4765208

Publications 1972

Torsvik H, Børresen A, Berg K, Boman H (1972)
Preliminary assignment of the inherited Hl 1 antigen to the apoA-I polypeptide of rabbit high density lipoprotein
FEBS Lett, 28 (2), 153-155
PubMed 11946845