Bjarne Bogen
Position: Group leader
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Author network for Bjarne Bogen by COREMINE medical


Publications 2017

Gudjonsson A, Lysén A, Balan S, Sundvold-Gjerstad V, Arnold-Schrauf C, Richter L, Bækkevold ES, Dalod M, Bogen B, Fossum E (2017)
Targeting Influenza Virus Hemagglutinin to Xcr1(+) Dendritic Cells in the Absence of Receptor-Mediated Endocytosis Enhances Protective Antibody Responses
J Immunol, 198 (7), 2785-2795
PubMed 28228559

Wang D, Fløisand Y, Myklebust CV, Bürgler S, Parente-Ribes A, Hofgaard PO, Bogen B, Tasken K, Tjønnfjord GE, Schjesvold F, Dalgaard J, Tveita A, Munthe LA (2017)
Autologous bone marrow Th cells can support multiple myeloma cell proliferation in vitro and in xenografted mice
Leukemia (in press)
PubMed 28232741

Publications 2016

Andersen AN, Landsverk OJ, Simonsen A, Bogen B, Corthay A, Øynebråten I (2016)
Coupling of HIV-1 Antigen to the Selective Autophagy Receptor SQSTM1/p62 Promotes T-Cell-Mediated Immunity
Front Immunol, 7, 167
PubMed 27242780

Ardouin L, Luche H, Chelbi R, Carpentier S, Shawket A, Montanana Sanchis F, Santa Maria C, Grenot P, Alexandre Y, Grégoire C, Fries A, Vu Manh TP, Tamoutounour S, Crozat K, Tomasello E, Jorquera A, Fossum E, Bogen B, Azukizawa H, Bajenoff M, Henri S, Dalod M, Malissen B (2016)
Broad and Largely Concordant Molecular Changes Characterize Tolerogenic and Immunogenic Dendritic Cell Maturation in Thymus and Periphery
Immunity, 45 (2), 305-18
PubMed 27533013

Bartee E, Bartee MY, Bogen B, Yu XZ (2016)
Systemic therapy with oncolytic myxoma virus cures established residual multiple myeloma in mice
Mol Ther Oncolytics, 3, 16032
PubMed 27933316

Deloizy C, Bouguyon E, Fossum E, Sebo P, Osicka R, Bole A, Pierres M, Biacchesi S, Dalod M, Bogen B, Bertho N, Schwartz-Cornil I (2016)
Expanding the tools for identifying mononuclear phagocyte subsets in swine: Reagents to porcine CD11c and XCR1
Dev Comp Immunol, 65, 31-40
PubMed 27345169

Grodeland G, Fredriksen AB, Løset GÅ, Vikse E, Fugger L, Bogen B (2016)
Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination
J Immunol, 197 (9), 3575-3585
PubMed 27671110

Guilliams M, Dutertre CA, Scott CL, McGovern N, Sichien D, Chakarov S, Van Gassen S, Chen J, Poidinger M, De Prijck S, Tavernier SJ, Low I, Irac SE, Mattar CN, Sumatoh HR, Low GH, Chung TJ, Chan DK, Tan KK, Hon TL, Fossum E, Bogen B, Choolani M, Chan JK, Larbi A et al. (2016)
Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species
Immunity, 45 (3), 669-84
PubMed 27637149

Lambert L, Kinnear E, McDonald JU, Grodeland G, Bogen B, Stubsrud E, Lindeberg MM, Fredriksen AB, Tregoning JS (2016)
DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8(+) T Cell Responses, Enabling Faster Resolution of Influenza Disease
Front Immunol, 7, 321
PubMed 27602032

Lorvik KB, Hammarström C, Fauskanger M, Haabeth OA, Zangani M, Haraldsen G, Bogen B, Corthay A (2016)
Adoptive Transfer of Tumor-Specific Th2 Cells Eradicates Tumors by Triggering an In Situ Inflammatory Immune Response
Cancer Res, 76 (23), 6864-6876
PubMed 27634753

Tveita A, Fauskanger M, Bogen B, Haabeth OA (2016)
Tumor-specific CD4+ T cells eradicate myeloma cells genetically deficient in MHC class II display
Oncotarget, 7 (41), 67175-67182
PubMed 27626487

Zhou P, Chionh YT, Irac SE, Ahn M, Jia Ng JH, Fossum E, Bogen B, Ginhoux F, Irving AT, Dutertre CA, Wang LF (2016)
Unlocking bat immunology: establishment of Pteropus alecto bone marrow-derived dendritic cells and macrophages
Sci Rep, 6, 38597
PubMed 27934903

Publications 2015

Baranowska M, Hauge AG, Hoornaert C, Bogen B, Grødeland G (2015)
Targeting of nucleoprotein to chemokine receptors by DNA vaccination results in increased CD8(+)-mediated cross protection against influenza
Vaccine, 33 (49), 6988-96
PubMed 26387432

Grødeland G, Bogen B (2015)
Efficient vaccine against pandemic influenza: combining DNA vaccination and targeted delivery to MHC class II molecules
Expert Rev Vaccines, 14 (6), 805-14
PubMed 25818107

Grødeland G, Fossum E, Bogen B (2015)
Polarizing T and B Cell Responses by APC-Targeted Subunit Vaccines
Front Immunol, 6, 367
PubMed 26257735

Haabeth OA, Lorvik KB, Yagita H, Bogen B, Corthay A (2015)
Interleukin-1 is required for cancer eradication mediated by tumor-specific Th1 cells
Oncoimmunology, 5 (1), e1039763
PubMed 26942052

Haabeth OA, Tveita A, Fauskanger M, Hennig K, Hofgaard PO, Bogen B (2015)
Idiotype-specific CD4(+) T cells eradicate disseminated myeloma
Leukemia, 30 (5), 1216-20
PubMed 26449664

Kikuchi J, Koyama D, Wada T, Izumi T, Hofgaard PO, Bogen B, Furukawa Y (2015)
Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma
J Clin Invest, 125 (12), 4375-90
PubMed 26517694

Kulkarni U, Karsten CM, Kohler T, Hammerschmidt S, Bommert K, Tiburzy B, Meng L, Thieme L, Recke A, Ludwig RJ, Pollok K, Kalies K, Bogen B, Boettcher M, Kamradt T, Hauser AE, Langer C, Huber-Lang M, Finkelman FD, Köhl J, Wong DM, Manz RA (2015)
IL-10 mediates plasmacytosis-associated immunodeficiency by inhibiting complement-mediated neutrophil migration
J Allergy Clin Immunol, 137 (5), 1487-1497.e6
PubMed 26653800

Matthes T, Manfroi B, Zeller A, Dunand-Sauthier I, Bogen B, Huard B (2015)
Autocrine amplification of immature myeloid cells by IL-6 in multiple myeloma-infiltrated bone marrow
Leukemia, 29 (9), 1882-90
PubMed 26159051

Parente-Ribes A, Skånland SS, Bürgler S, Os A, Wang D, Bogen B, Tjønnfjord GE, Taskén K, Munthe LA (2015)
Spleen tyrosine kinase inhibitors reduce CD40L-induced proliferation of chronic lymphocytic leukemia cells but not normal B cells
Haematologica, 101 (2), e59-62
PubMed 26589914

Terhorst D, Fossum E, Baranska A, Tamoutounour S, Malosse C, Garbani M, Braun R, Lechat E, Crameri R, Bogen B, Henri S, Malissen B (2015)
Laser-assisted intradermal delivery of adjuvant-free vaccines targeting XCR1+ dendritic cells induces potent antitumoral responses
J Immunol, 194 (12), 5895-902
PubMed 25941327

Tveita AA, Schjesvold F, Haabeth OA, Fauskanger M, Bogen B (2015)
Tumors Escape CD4+ T-cell-Mediated Immunosurveillance by Impairing the Ability of Infiltrating Macrophages to Indirectly Present Tumor Antigens
Cancer Res, 75 (16), 3268-78
PubMed 26038231

Aas-Hanssen K, Thompson KM, Bogen B, Munthe LA (2015)
Systemic Lupus Erythematosus: Molecular Mimicry between Anti-dsDNA CDR3 Idiotype, Microbial and Self Peptides-As Antigens for Th Cells
Front Immunol, 6, 382
PubMed 26284067

Publications 2014

Balan S, Ollion V, Colletti N, Chelbi R, Montanana-Sanchis F, Liu H, Vu Manh TP, Sanchez C, Savoret J, Perrot I, Doffin AC, Fossum E, Bechlian D, Chabannon C, Bogen B, Asselin-Paturel C, Shaw M, Soos T, Caux C, Valladeau-Guilemond J, Dalod M (2014)
Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells
J Immunol, 193 (4), 1622-35
PubMed 25009205

Binsfeld M, Beguin Y, Belle L, Otjacques E, Hannon M, Briquet A, Heusschen R, Drion P, Zilberberg J, Bogen B, Baron F, Caers J (2014)
Establishment of a murine graft-versus-myeloma model using allogeneic stem cell transplantation
PLoS One, 9 (11), e113764
PubMed 25415267

Bürgler S, Gimeno A, Parente-Ribes A, Wang D, Os A, Devereux S, Jebsen P, Bogen B, Tjønnfjord GE, Munthe LA (2014)
Chronic lymphocytic leukemia cells express CD38 in response to Th1 cell-derived IFN-γ by a T-bet-dependent mechanism
J Immunol, 194 (2), 827-35
PubMed 25505279

Dutertre CA, Jourdain JP, Rancez M, Amraoui S, Fossum E, Bogen B, Sanchez C, Couëdel-Courteille A, Richard Y, Dalod M, Feuillet V, Cheynier R, Hosmalin A (2014)
TLR3-responsive, XCR1+, CD141(BDCA-3)+/CD8α+-equivalent dendritic cells uncovered in healthy and simian immunodeficiency virus-infected rhesus macaques
J Immunol, 192 (10), 4697-708
PubMed 24740505

Fossum E, Grødeland G, Terhorst D, Tveita AA, Vikse E, Mjaaland S, Henri S, Malissen B, Bogen B (2014)
Vaccine molecules targeting Xcr1 on cross-presenting DCs induce protective CD8+ T-cell responses against influenza virus
Eur J Immunol, 45 (2), 624-35
PubMed 25410055

Haabeth OA, Tveita AA, Fauskanger M, Schjesvold F, Lorvik KB, Hofgaard PO, Omholt H, Munthe LA, Dembic Z, Corthay A, Bogen B (2014)
How Do CD4(+) T Cells Detect and Eliminate Tumor Cells That Either Lack or Express MHC Class II Molecules?
Front Immunol, 5, 174
PubMed 24782871

Jacobsen J, Haabeth OA, Tveita AA, Schjetne KW, Munthe LA, Bogen B (2014)
Naive idiotope-specific B and T cells collaborate efficiently in the absence of dendritic cells
J Immunol, 192 (9), 4174-83
PubMed 24706724

Løvås TO, Bruusgaard JC, Øynebråten I, Gundersen K, Bogen B (2014)
DNA vaccines: MHC II-targeted vaccine protein produced by transfected muscle fibres induces a local inflammatory cell infiltrate in mice
PLoS One, 9 (10), e108069
PubMed 25299691

Ruffini PA, Os A, Dolcetti R, Tjønnfjord GE, Munthe LA, Bogen B (2014)
Targeted DNA vaccines eliciting crossreactive anti-idiotypic antibody responses against human B cell malignancies in mice
J Transl Med, 12, 207
PubMed 25059102

Schwarzer R, Nickel N, Godau J, Willie BM, Duda GN, Schwarzer R, Cirovic B, Leutz A, Manz R, Bogen B, Dörken B, Jundt F (2014)
Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model
Blood Cancer J, 4, e217
PubMed 24927406

Tveita AA, Haabeth OA, Bogen B (2014)
Limitations of bystander killing in Th1/M1 immune responses against a secreted tumor antigen
Oncoimmunology, 3 (9), e954953
PubMed 25941607

Tveita AA, Schjesvold FH, Sundnes O, Haabeth OA, Haraldsen G, Bogen B (2014)
Indirect CD4+ T-cell-mediated elimination of MHC II(NEG) tumor cells is spatially restricted and fails to prevent escape of antigen-negative cells
Eur J Immunol, 44 (9), 2625-37
PubMed 24846412

Wong D, Winter O, Hartig C, Siebels S, Szyska M, Tiburzy B, Meng L, Kulkarni U, Fähnrich A, Bommert K, Bargou R, Berek C, Chu VT, Bogen B, Jundt F, Manz RA (2014)
Eosinophils and megakaryocytes support the early growth of murine MOPC315 myeloma cells in their bone marrow niches
PLoS One, 9 (10), e109018
PubMed 25272036

Øynebråten I, Hinkula J, Fredriksen AB, Bogen B (2014)
Increased generation of HIV-1 gp120-reactive CD8+ T cells by a DNA vaccine construct encoding the chemokine CCL3
PLoS One, 9 (8), e104814
PubMed 25122197

Aas-Hanssen K, Funderud A, Thompson KM, Bogen B, Munthe LA (2014)
Idiotype-specific Th cells support oligoclonal expansion of anti-dsDNA B cells in mice with lupus
J Immunol, 193 (6), 2691-8
PubMed 25127856

Publications 2013

Frigstad T, Løset GÅ, Sandlie I, Bogen B (2013)
A public T cell receptor recognized by a monoclonal antibody specific for the D-J junction of the β-chain
Scand J Immunol, 78 (4), 345-51
PubMed 23841814

Grodeland G, Mjaaland S, Roux KH, Fredriksen AB, Bogen B (2013)
DNA vaccine that targets hemagglutinin to MHC class II molecules rapidly induces antibody-mediated protection against influenza
J Immunol, 191 (6), 3221-31
PubMed 23956431

Grødeland G, Mjaaland S, Tunheim G, Fredriksen AB, Bogen B (2013)
The specificity of targeted vaccines for APC surface molecules influences the immune response phenotype
PLoS One, 8 (11), e80008
PubMed 24244595

Gunnarsen KS, Kristinsson SG, Justesen S, Frigstad T, Buus S, Bogen B, Sandlie I, Løset GÅ (2013)
Chaperone-assisted thermostability engineering of a soluble T cell receptor using phage display
Sci Rep, 3, 1162
PubMed 23362461

Hong S, Lee H, Jung K, Lee SM, Lee SJ, Jun HJ, Kim Y, Song H, Bogen B, Choi I (2013)
Tumor cells loaded with α-galactosylceramide promote therapeutic NKT-dependent anti-tumor immunity in multiple myeloma
Immunol Lett, 156 (1-2), 132-9
PubMed 24148970

Jacobsen JT, Sundvold-Gjerstad V, Skjeldal FM, Andersen JT, Abrahamsen G, Bakke O, Spurkland A, Bogen B (2013)
B-cell tolerance to the B-cell receptor variable regions
Eur J Immunol, 43 (10), 2577-87
PubMed 23839948

Lorvik KB, Haabeth OA, Clancy T, Bogen B, Corthay A (2013)
Molecular profiling of tumor-specific TH1 cells activated in vivo
Oncoimmunology, 2 (5), e24383
PubMed 23762808

Os A, Bürgler S, Ribes AP, Funderud A, Wang D, Thompson KM, Tjønnfjord GE, Bogen B, Munthe LA (2013)
Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells
Cell Rep, 4 (3), 566-77
PubMed 23933259

Publications 2012

Berge T, Grønningsæter IH, Lorvik KB, Abrahamsen G, Granum S, Sundvold-Gjerstad V, Corthay A, Bogen B, Spurkland A (2012)
SH2D2A modulates T cell mediated protection to a B cell derived tumor in transgenic mice
PLoS One, 7 (10), e48239
PubMed 23144743

Fredriksen AB, Sandlie I, Bogen B (2012)
Targeted DNA vaccines for enhanced induction of idiotype-specific B and T cells
Front Oncol, 2, 154
PubMed 23115759

Heimberger T, Andrulis M, Riedel S, Stühmer T, Schraud H, Beilhack A, Bumm T, Bogen B, Einsele H, Bargou RC, Chatterjee M (2012)
The heat shock transcription factor 1 as a potential new therapeutic target in multiple myeloma
Br J Haematol, 160 (4), 465-76
PubMed 23252346

Hofgaard PO, Jodal HC, Bommert K, Huard B, Caers J, Carlsen H, Schwarzer R, Schünemann N, Jundt F, Lindeberg MM, Bogen B (2012)
A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease
PLoS One, 7 (12), e51892
PubMed 23284805

Haabeth OA, Bogen B, Corthay A (2012)
A model for cancer-suppressive inflammation
Oncoimmunology, 1 (7), 1146-1155
PubMed 23170261

Lorvik KB, Bogen B, Corthay A (2012)
Fingolimod blocks immunosurveillance of myeloma and B-cell lymphoma resulting in cancer development in mice
Blood, 119 (9), 2176-7
PubMed 22383793

Nilssen NR, Frigstad T, Pollmann S, Roos N, Bogen B, Sandlie I, Løset GÅ (2012)
DeltaPhage--a novel helper phage for high-valence pIX phagemid display
Nucleic Acids Res, 40 (16), e120
PubMed 22539265

Rasmussen IB, Oynebråten I, Høydahl LS, Flobakk M, Lunde E, Michaelsen TE, Bogen B, Sandlie I (2012)
CD40/APC-specific antibodies with three T-cell epitopes loaded in the constant domains induce CD4+ T-cell responses
Protein Eng Des Sel, 25 (3), 89-96
PubMed 22233931

Riedel SS, Mottok A, Brede C, Bäuerlein CA, Jordán Garrote AL, Ritz M, Mattenheimer K, Rosenwald A, Einsele H, Bogen B, Beilhack A (2012)
Non-invasive imaging provides spatiotemporal information on disease progression and response to therapy in a murine model of multiple myeloma
PLoS One, 7 (12), e52398
PubMed 23300660

Spång HC, Braathen R, Bogen B (2012)
Heterodimeric barnase-barstar vaccine molecules: influence of one versus two targeting units specific for antigen presenting cells
PLoS One, 7 (9), e45393
PubMed 23028981

Øynebråten I, Løvås TO, Thompson K, Bogen B (2012)
Generation of antibody-producing hybridomas following one single immunization with a targeted DNA vaccine
Scand J Immunol, 75 (4), 379-88
PubMed 21955209

Publications 2011

Bogen B (2011)
Welcome to the 40th Scandinavian Society for Immunology meeting at Geilo, Norway
Scand. J. Immunol., 73 (4), 267

Bogen B (2011)
Lymphoma invisibility-vaccination-attack?
Blood, 117 (5), 1437-8
PubMed 21292780

Corthay A, Lorvik KB, Bogen B (2011)
Is secretion of tumour-specific antigen important for cancer eradication by CD4(+) T cells?--Implications for cancer immunotherapy by adoptive T cell transfer
Scand J Immunol, 73 (6), 527-30
PubMed 21388431

Crozat K, Tamoutounour S, Vu Manh TP, Fossum E, Luche H, Ardouin L, Guilliams M, Azukizawa H, Bogen B, Malissen B, Henri S, Dalod M (2011)
Cutting edge: expression of XCR1 defines mouse lymphoid-tissue resident and migratory dendritic cells of the CD8α+ type
J Immunol, 187 (9), 4411-5
PubMed 21948982

Follin-Arbelet V, Hofgaard PO, Hauglin H, Naderi S, Sundan A, Blomhoff R, Bogen B, Blomhoff HK (2011)
Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model
BMC Cancer, 11, 301
PubMed 21767374

Frøyland M, Ruffini PA, Thompson KM, Gedde-Dahl T, Fredriksen AB, Bogen B (2011)
Targeted idiotype-fusion DNA vaccines for human multiple myeloma: preclinical testing
Eur J Haematol, 86 (5), 385-95
PubMed 21332794

Haabeth OA, Lorvik KB, Hammarström C, Donaldson IM, Haraldsen G, Bogen B, Corthay A (2011)
Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer
Nat Commun, 2, 240
PubMed 21407206

Løset GÅ, Bogen B, Sandlie I (2011)
Expanding the versatility of phage display I: efficient display of peptide-tags on protein VII of the filamentous phage
PLoS One, 6 (2), e14702
PubMed 21390217

Løset GÅ, Roos N, Bogen B, Sandlie I (2011)
Expanding the versatility of phage display II: improved affinity selection of folded domains on protein VII and IX of the filamentous phage
PLoS One, 6 (2), e17433
PubMed 21390283

Publications 2010

Gunnarsen KS, Lunde E, Kristiansen PE, Bogen B, Sandlie I, Løset GÅ (2010)
Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA
BMC Biotechnol, 10, 8
PubMed 20128915

Jacobsen JT, Lunde E, Sundvold-Gjerstad V, Munthe LA, Bogen B (2010)
The cellular mechanism by which complementary Id+ and anti-Id antibodies communicate: T cells integrated into idiotypic regulation
Immunol Cell Biol, 88 (5), 515-22
PubMed 20066000

Lunde E, Løset GÅ, Bogen B, Sandlie I (2010)
Stabilizing mutations increase secretion of functional soluble TCR-Ig fusion proteins
BMC Biotechnol, 10, 61
PubMed 20735812

Ruffini PA, Grødeland G, Fredriksen AB, Bogen B (2010)
Human chemokine MIP1α increases efficiency of targeted DNA fusion vaccines
Vaccine, 29 (2), 191-9
PubMed 21055498

Publications 2009

Bogen B, Ruffini P (2009)
Review: to what extent are T cells tolerant to immunoglobulin variable regions?
Scand J Immunol, 70 (6), 526-30
PubMed 19906193

Corthay A, Lundin KU, Lorvik KB, Hofgaard PO, Bogen B (2009)
Secretion of tumor-specific antigen by myeloma cells is required for cancer immunosurveillance by CD4+ T cells
Cancer Res, 69 (14), 5901-7
PubMed 19567679

Holmøy T, Vartdal F, Hestvik AL, Munthe L, Bogen B (2009)
The idiotype connection: linking infection and multiple sclerosis
Trends Immunol, 31 (2), 56-62
PubMed 19962346

Zangani M, Carlsen H, Kielland A, Os A, Hauglin H, Blomhoff R, Munthe LA, Bogen B (2009)
Tracking early autoimmune disease by bioluminescent imaging of NF-kappaB activation reveals pathology in multiple organ systems
Am J Pathol, 174 (4), 1358-67
PubMed 19286564

Publications 2008

Flobakk M, Rasmussen IB, Lunde E, Frigstad T, Berntzen G, Michaelsen TE, Bogen B, Sandlie I (2008)
Processing of an antigenic sequence from IgG constant domains for presentation by MHC class II
J Immunol, 181 (10), 7062-72
PubMed 18981126

Tunheim G, Schjetne KW, Rasmussen IB, Sollid LM, Sandlie I, Bogen B (2008)
Recombinant antibodies for delivery of antigen: a single loop between beta-strands in the constant region can accommodate long, complex and tandem T cell epitopes
Int Immunol, 20 (3), 295-306
PubMed 18252695

Publications 2007

Fredriksen AB, Bogen B (2007)
Chemokine-idiotype fusion DNA vaccines are potentiated by bivalency and xenogeneic sequences
Blood, 110 (6), 1797-805
PubMed 17540847

Frøyland M, Thompson KM, Thorpe SJ, Sahota SS, Gedde-Dahl T, Bogen B (2007)
A VH4-34+ myeloma protein with weak autoreactivity
Haematologica, 92 (5), 690-3
PubMed 17488696

Hestvik AL, Vartdal F, Fredriksen AB, Thompson KM, Kvale EO, Skorstad G, Bogen B, Holmoy T (2007)
T cells from multiple sclerosis patients recognize multiple epitopes on Self-IgG
Scand J Immunol, 66 (4), 393-401
PubMed 17850583

Kolltveit KM, Granum S, Aasheim HC, Forsbring M, Sundvold-Gjerstad V, Dai KZ, Molberg O, Schjetne KW, Bogen B, Shapiro VS, Johansen FE, Schenck K, Spurkland A (2007)
Expression of SH2D2A in T-cells is regulated both at the transcriptional and translational level
Mol Immunol, 45 (8), 2380-90
PubMed 18160104

Løset GÅ, Lunde E, Bogen B, Brekke OH, Sandlie I (2007)
Functional phage display of two murine alpha/beta T-cell receptors is strongly dependent on fusion format, mode and periplasmic folding assistance
Protein Eng Des Sel, 20 (9), 461-72
PubMed 17925331

Ráki M, Schjetne KW, Stamnaes J, Molberg Ø, Jahnsen FL, Issekutz TB, Bogen B, Sollid LM (2007)
Surface expression of transglutaminase 2 by dendritic cells and its potential role for uptake and presentation of gluten peptides to T cells
Scand J Immunol, 65 (3), 213-20
PubMed 17309775

Schjetne KW, Fredriksen AB, Bogen B (2007)
Delivery of antigen to CD40 induces protective immune responses against tumors
J Immunol, 178 (7), 4169-76
PubMed 17371973

Tunheim G, Thompson KM, Fredriksen AB, Espevik T, Schjetne KW, Bogen B (2007)
Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates
Vaccine, 25 (24), 4723-34
PubMed 17499405

Zangani MM, Frøyland M, Qiu GY, Meza-Zepeda LA, Kutok JL, Thompson KM, Munthe LA, Bogen B (2007)
Lymphomas can develop from B cells chronically helped by idiotype-specific T cells
J Exp Med, 204 (5), 1181-91
PubMed 17485509

Publications 2006

Bogen B, Ruffini PA, Corthay A, Fredriksen AB, Frøyland M, Lundin K, Røsjø E, Thompson K, Massaia M (2006)
Idiotype-specific immunotherapy in multiple myeloma: suggestions for future directions of research
Haematologica, 91 (7), 941-8
PubMed 16818282

Fredriksen AB, Sandlie I, Bogen B (2006)
DNA vaccines increase immunogenicity of idiotypic tumor antigen by targeting novel fusion proteins to antigen-presenting cells
Mol Ther, 13 (4), 776-85
PubMed 16414309

Husebye H, Halaas Ø, Stenmark H, Tunheim G, Sandanger Ø, Bogen B, Brech A, Latz E, Espevik T (2006)
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
EMBO J, 25 (4), 683-92
PubMed 16467847

Kjeken R, Bogen B, Mathiesen I (2006)
[DNA--the future in vaccine technology?]
Tidsskr Nor Laegeforen, 126 (22), 2964-8
PubMed 17117196

Publications 2005

Corthay A, Skovseth DK, Lundin KU, Røsjø E, Omholt H, Hofgaard PO, Haraldsen G, Bogen B (2005)
Primary antitumor immune response mediated by CD4+ T cells
Immunity, 22 (3), 371-83
PubMed 15780993

Holmøy T, Fredriksen AB, Thompson KM, Hestvik AL, Bogen B, Vartdal F (2005)
Cerebrospinal fluid T cell clones from patients with multiple sclerosis: recognition of idiotopes on monoclonal IgG secreted by autologous cerebrospinal fluid B cells
Eur J Immunol, 35 (6), 1786-94
PubMed 15864781

Munthe LA, Corthay A, Os A, Zangani M, Bogen B (2005)
Systemic autoimmune disease caused by autoreactive B cells that receive chronic help from Ig V region-specific T cells
J Immunol, 175 (4), 2391-400
PubMed 16081810

Schjetne KW, Thommesen JE, Fredriksen AB, Lunde E, Sandlie I, Bogen B (2005)
Induction of central T cell tolerance: recombinant antibodies deliver peptides for deletion of antigen-specific (CD4+)8+ thymocytes
Eur J Immunol, 35 (11), 3142-52
PubMed 16184515

Publications 2004

Corthay A, Lundin KU, Munthe LA, Frøyland M, Gedde-Dahl T, Dembic Z, Bogen B (2004)
Immunotherapy in multiple myeloma: Id-specific strategies suggested by studies in animal models
Cancer Immunol Immunother, 53 (9), 759-69
PubMed 15088126

Dembic Z, Hofgaard PO, Omholt H, Bogen B (2004)
Anti-class II antibodies, but not cytotoxic T-lymphocyte antigen 4-immunoglobulin hybrid molecules, prevent rejection of major histocompatibility complex class II-negative myeloma in T-cell receptor-transgenic mice
Scand J Immunol, 60 (1-2), 143-52
PubMed 15238083

Etokebe GE, Abrahamsen TG, Bogen B, Spurkland A (2004)
Tumour necrosis factor receptor superfamily member 6 gene mutation detection by denaturing high-performance liquid chromatography
Scand J Immunol, 59 (5), 496-503
PubMed 15140060

Lundin KU, Screpanti V, Omholt H, Hofgaard PO, Yagita H, Grandien A, Bogen B (2004)
CD4+ T cells kill Id+ B-lymphoma cells: FasLigand-Fas interaction is dominant in vitro but is redundant in vivo
Cancer Immunol Immunother, 53 (12), 1135-45
PubMed 15696611

Munthe LA, Os A, Zangani M, Bogen B (2004)
MHC-restricted Ig V region-driven T-B lymphocyte collaboration: B cell receptor ligation facilitates switch to IgG production
J Immunol, 172 (12), 7476-84
PubMed 15187126

Ruffini PA, Biragyn A, Coscia M, Harvey LK, Cha SC, Bogen B, Kwak LW (2004)
Genetic fusions with viral chemokines target delivery of nonimmunogenic antigen to trigger antitumor immunity independent of chemotaxis
J Leukoc Biol, 76 (1), 77-85
PubMed 15075363

Tjelle TE, Corthay A, Lunde E, Sandlie I, Michaelsen TE, Mathiesen I, Bogen B (2004)
Monoclonal antibodies produced by muscle after plasmid injection and electroporation
Mol Ther, 9 (3), 328-36
PubMed 15006599

Tunheim G, Schjetne KW, Fredriksen AB, Sandlie I, Bogen B (2004)
Human CD14 is an efficient target for recombinant immunoglobulin vaccine constructs that deliver T cell epitopes
J Leukoc Biol, 77 (3), 303-10
PubMed 15576418

Publications 2003

Dellacasagrande J, Schreurs OJ, Hofgaard PO, Omholt H, Steinsvoll S, Schenck K, Bogen B, Dembic Z (2003)
Liver metastasis of cancer facilitated by chemokine receptor CCR6
Scand J Immunol, 57 (6), 534-44
PubMed 12791091

Lundin KU, Hofgaard PO, Omholt H, Munthe LA, Corthay A, Bogen B (2003)
Therapeutic effect of idiotype-specific CD4+ T cells against B-cell lymphoma in the absence of anti-idiotypic antibodies
Blood, 102 (2), 605-12
PubMed 12649166

Schjetne KW, Gundersen HT, Iversen JG, Thompson KM, Bogen B (2003)
Antibody-mediated delivery of antigen to chemokine receptors on antigen-presenting cells results in enhanced CD4+ T cell responses
Eur J Immunol, 33 (11), 3101-8
PubMed 14579278

Schjetne KW, Thompson KM, Nilsen N, Flo TH, Fleckenstein B, Iversen JG, Espevik T, Bogen B (2003)
Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target
J Immunol, 171 (1), 32-6
PubMed 12816980

Publications 2002

Bogen B (2002)
A mouse model for immunotherapy of myeloma
Hematol J, 3 (5), 224-9
PubMed 12391539

Lunde E, Lauvrak V, Rasmussen IB, Schjetne KW, Thompson KM, Michaelsen TE, Brekke OH, Sollid LM, Bogen B, Sandlie I (2002)
Troybodies and pepbodies
Biochem Soc Trans, 30 (4), 500-6
PubMed 12196123

Lunde E, Western KH, Rasmussen IB, Sandlie I, Bogen B (2002)
Efficient delivery of T cell epitopes to APC by use of MHC class II-specific Troybodies
J Immunol, 168 (5), 2154-62
PubMed 11859101

Schjetne KW, Thompson KM, Aarvak T, Fleckenstein B, Sollid LM, Bogen B (2002)
A mouse C kappa-specific T cell clone indicates that DC-SIGN is an efficient target for antibody-mediated delivery of T cell epitopes for MHC class II presentation
Int Immunol, 14 (12), 1423-30
PubMed 12456590

Publications 2001

Dembic Z, Røttingen JA, Dellacasagrande J, Schenck K, Bogen B (2001)
Phagocytic dendritic cells from myelomas activate tumor-specific T cells at a single cell level
Blood, 97 (9), 2808-14
PubMed 11313275

Lund E, Rasmussen IB, Western KH, Eidem JK, Sandlie I, Bogen B (2001)
"Troy-bodies": recombinant antibodies that target T cell epitopes to antigen presenting cells
Int Rev Immunol, 20 (5), 647-73
PubMed 11890617

Lunde E, Rasmussen IB, Eidem JK, Gregers TF, Western KH, Bogen B, Sandlie I (2001)
'Troy-bodies': antibodies as vector proteins for T cell epitopes
Biomol Eng, 18 (3), 109-16
PubMed 11566602

McAdam SN, Fleckenstein B, Rasmussen IB, Schmid DG, Sandlie I, Bogen B, Viner NJ, Sollid LM (2001)
T cell recognition of the dominant I-A(k)-restricted hen egg lysozyme epitope: critical role for asparagine deamidation
J Exp Med, 193 (11), 1239-46
PubMed 11390431

Rasmussen IB, Lunde E, Michaelsen TE, Bogen B, Sandlie I (2001)
The principle of delivery of T cell epitopes to antigen-presenting cells applied to peptides from influenza virus, ovalbumin, and hen egg lysozyme: implications for peptide vaccination
Proc Natl Acad Sci U S A, 98 (18), 10296-301
PubMed 11517321

Publications 2000

Bogen B, Schenck K, Munthe LA, Dembic Z (2000)
Deletion of idiotype (Id)-specific T cells in multiple myeloma
Acta Oncol, 39 (7), 783-8
PubMed 11145433

Dembic Z, Schenck K, Bogen B (2000)
Dendritic cells purified from myeloma are primed with tumor-specific antigen (idiotype) and activate CD4+ T cells
Proc Natl Acad Sci U S A, 97 (6), 2697-702
PubMed 10706628

Eidem JK, Rasmussen IB, Lunde E, Gregers TF, Rees AR, Bogen B, Sandlie I (2000)
Recombinant antibodies as carrier proteins for sub-unit vaccines: influence of mode of fusion on protein production and T-cell activation
J Immunol Methods, 245 (1-2), 119-31
PubMed 11042289

Publications 1999

Djerbi M, Screpanti V, Catrina AI, Bogen B, Biberfeld P, Grandien A (1999)
The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors
J Exp Med, 190 (7), 1025-32
PubMed 10510092

Lunde E, Munthe LA, Vabø A, Sandlie I, Bogen B (1999)
Antibodies engineered with IgD specificity efficiently deliver integrated T-cell epitopes for antigen presentation by B cells
Nat Biotechnol, 17 (7), 670-5
PubMed 10404160

Munthe LA, Kyte JA, Bogen B (1999)
Resting small B cells present endogenous immunoglobulin variable-region determinants to idiotope-specific CD4(+) T cells in vivo
Eur J Immunol, 29 (12), 4043-52
PubMed 10602015

Publications 1998

Bogen B (1998)
[Kaspase or caspase?]
Tidsskr Nor Laegeforen, 118 (30), 4790
PubMed 9914770

Dembic Z, Munthe LA, Schenck K, Mueller C, Bogen B (1998)
Transient overexpression of CD4 enhances allelic exclusion of T-cell receptor (TCR) alpha chains and promotes positive selection of class II-restricted TCR-transgenic thymocytes
Mol Immunol, 35 (1), 23-38
PubMed 9683261

Engel H, Bogen B, Müller U, Andersson J, Rolink A, Weiss S (1998)
Expression level of a transgenic lambda2 chain results in isotype exclusion and commitment to B1 cells
Eur J Immunol, 28 (8), 2289-99
PubMed 9710207

Lauritzsen GF, Hofgaard PO, Schenck K, Bogen B (1998)
Clonal deletion of thymocytes as a tumor escape mechanism
Int J Cancer, 78 (2), 216-22
PubMed 9754655

Sim BC, Aftahi N, Reilly C, Bogen B, Schwartz RH, Gascoigne NR, Lo D (1998)
Thymic skewing of the CD4/CD8 ratio maps with the T-cell receptor alpha-chain locus
Curr Biol, 8 (12), 701-4
PubMed 9637921

Publications 1997

Bogen B (1997)
[University medicine in Silicon Valley]
Tidsskr Nor Laegeforen, 117 (11), 1641-2
PubMed 9198951

Lunde E, Bogen B, Sandlie I (1997)
Immunoglobulin as a vehicle for foreign antigenic peptides immunogenic to T cells
Mol Immunol, 34 (16-17), 1167-76
PubMed 9566764

Reichardt VL, Okada CY, Stockerl-Goldstein KE, Bogen B, Levy R (1997)
Rationale for adjuvant idiotypic vaccination after high-dose therapy for multiple myeloma
Biol Blood Marrow Transplant, 3 (3), 157-63
PubMed 9310193

Publications 1996

Blichfeldt E, Munthe LA, Røtnes JS, Bogen B (1996)
Dual T cell receptor T cells have a decreased sensitivity to physiological ligands due to reduced density of each T cell receptor
Eur J Immunol, 26 (12), 2876-84
PubMed 8977280

Bogen B (1996)
Peripheral T cell tolerance as a tumor escape mechanism: deletion of CD4+ T cells specific for a monoclonal immunoglobulin idiotype secreted by a plasmacytoma
Eur J Immunol, 26 (11), 2671-9
PubMed 8921954

Bot A, Nangpal A, Pricop L, Bogen B, Kaushik A, Bona CA (1996)
V lambda-light chain genes reconstitute immune responses to defined carbohydrate antigens or haptens by utilizing different VH genes
Mol Immunol, 33 (17-18), 1359-68
PubMed 9171895

Munthe LA, Blichfeldt E, Sollien A, Dembic Z, Bogen B (1996)
T cells with two Tcrbeta chains and reactivity to both MHC/idiotypic peptide and superantigen
Cell Immunol, 170 (2), 283-90
PubMed 8660828

Publications 1995

Bogen B, Munthe L, Sollien A, Hofgaard P, Omholt H, Dagnaes F, Dembic Z, Lauritzsen GF (1995)
Naive CD4+ T cells confer idiotype-specific tumor resistance in the absence of antibodies
Eur J Immunol, 25 (11), 3079-86
PubMed 7489746

Dybwad A, Bogen B, Natvig JB, Førre O, Sioud M (1995)
Peptide phage libraries can be an efficient tool for identifying antibody ligands for polyclonal antisera
Clin Exp Immunol, 102 (2), 438-42
PubMed 7586703

Munthe LA, Sollien A, Dembic Z, Bogen B (1995)
Preferential positive selection of T lymphocytes which express two different TCR alpha chains, an endogenous and a transgenic
Scand J Immunol, 42 (6), 651-61
PubMed 8552989

Publications 1994

Dembić Z, Weiss S, Bogen B (1994)
Thymic selection of immunoglobulin idiotype specific T-cells
Thymus, 22 (3), 141-52
PubMed 7940642

Lauritzsen GF, Weiss S, Dembic Z, Bogen B (1994)
Naive idiotype-specific CD4+ T cells and immunosurveillance of B-cell tumors
Proc Natl Acad Sci U S A, 91 (12), 5700-4
PubMed 7911244

Røtnes JS, Bogen B (1994)
Ca2+ mobilization in physiologically stimulated single T cells gradually increases with peptide concentration (analog signaling)
Eur J Immunol, 24 (4), 851-8
PubMed 8149956

Publications 1993

Bogen B, Dembic Z, Weiss S (1993)
Clonal deletion of specific thymocytes by an immunoglobulin idiotype
EMBO J, 12 (1), 357-63
PubMed 8428591

Bogen B, Gleditsch L, Teig A (1993)
T-cell receptor alpha haplotype influences V alpha epitope expression on both cortisone-resistant thymocytes and lymph node T cells
Scand J Immunol, 37 (6), 690-5
PubMed 7686302

Bogen B, Weiss S (1993)
Processing and presentation of idiotypes to MHC-restricted T cells
Int Rev Immunol, 10 (4), 337-55
PubMed 8294847

Lauritzsen GF, Bogen B (1993)
The role of idiotype-specific, CD4+ T cells in tumor resistance against major histocompatibility complex class II molecule negative plasmacytoma cells
Cell Immunol, 148 (1), 177-88
PubMed 8098665

Lauritzsen GF, Weiss S, Bogen B (1993)
Anti-tumour activity of idiotype-specific, MHC-restricted Th1 and Th2 clones in vitro and in vivo
Scand J Immunol, 37 (1), 77-85
PubMed 8418475

Publications 1992

Bogen B, Gleditsch L, Weiss S, Dembic Z (1992)
Weak positive selection of transgenic T cell receptor-bearing thymocytes: importance of major histocompatibility complex class II, T cell receptor and CD4 surface molecule densities
Eur J Immunol, 22 (3), 703-9
PubMed 1547816

Gleditsch L, Bogen B (1992)
A Tcra congenic mouse: V alpha epitope expression is influenced by both Tcra haplotypes and background genes
Immunogenetics, 35 (3), 153-60
PubMed 1371498

Snodgrass HR, Fisher AM, Bruyns E, Bogen B (1992)
Restricted alpha/beta receptor gene usage of idiotype-specific major histocompatibility complex-restricted T cells: selection for CDR3-related sequences
Eur J Immunol, 22 (8), 2169-72
PubMed 1379189

Publications 1991

Bogen B, Weiss S (1991)
A rearranged lambda 2 light gene chain retards but does not exclude kappa and lambda 1 expression
Eur J Immunol, 21 (10), 2391-5
PubMed 1915552

Lauritzsen GF, Bogen B (1991)
Idiotype-specific, major histocompatibility complex restricted T cells are of both Th1 and Th2 type
Scand J Immunol, 33 (6), 647-56
PubMed 1675480

Weiss S, Bogen B (1991)
MHC class II-restricted presentation of intracellular antigen
Cell, 64 (4), 767-76
PubMed 1847667

Publications 1990

Bogen B, Lauritzsen GF, Weiss S (1990)
A stimulatory monoclonal antibody detecting T cell receptor diversity among idiotype-specific, major histocompatibility complex-restricted T cell clones
Eur J Immunol, 20 (10), 2359-62
PubMed 1700755

Gleditsch L, Snodgrass R, Bogen B (1990)
No recombinations between Tcra-V and Tcra-C gene segments in 669 backcross mice
Immunogenetics, 32 (5), 297-303
PubMed 1979062

Publications 1989

Bogen B (1989)
Monoclonal antibodies specific for variable and constant domains of murine lambda chains
Scand J Immunol, 29 (3), 273-9
PubMed 2497510

Bogen B, Lambris JD (1989)
Minimum length of an idiotypic peptide and a model for its binding to a major histocompatibility complex class II molecule
EMBO J, 8 (7), 1947-52
PubMed 2792076

Weiss S, Bogen B (1989)
B-lymphoma cells process and present their endogenous immunoglobulin to major histocompatibility complex-restricted T cells
Proc Natl Acad Sci U S A, 86 (1), 282-6
PubMed 2492101

Publications 1988

Bogen B, Weiss S (1988)
B lymphoma cells process and present their endogenous IG: implications for network theory
Adv Exp Med Biol, 237, 877-82
PubMed 3267071

Publications 1986

Bogen B, Malissen B, Haas W (1986)
Idiotope-specific T cell clones that recognize syngeneic immunoglobulin fragments in the context of class II molecules
Eur J Immunol, 16 (11), 1373-8
PubMed 3096740

Bogen B, Snodgrass R, Briand JP, Hannestad K (1986)
Synthetic peptides and beta-chain gene rearrangements reveal a diversified T cell repertoire for a lambda light chain third hypervariable region
Eur J Immunol, 16 (11), 1379-84
PubMed 3096741

Publications 1985

Bogen B (1985)
Dominant suppressive effect of the silent Eb alpha allele on an in vivo T helper cell response under Ed beta Ed alpha region-linked immune response gene control
Eur J Immunol, 15 (10), 1033-7
PubMed 2932337

Bogen B, Jørgensen T, Hannestad K (1985)
T helper cell recognition of idiotopes on lambda 2 light chains of M315 and T952: evidence for dependence on somatic mutations in the third hypervariable region
Eur J Immunol, 15 (3), 278-81
PubMed 2579823

Jørgensen T, Bogen B, Hannestad K (1985)
H-2-linked Ir genes have a striking influence on the immunogenicity of idiotopes of myeloma protein 315 for T helper cells
Scand J Immunol, 21 (2), 183-7
PubMed 3156401

Publications 1984

Bogen B (1984)
Antibody responses to lambda 1J558 and lambda 2315 light chains. Specificity and genetic regulation
Scand J Immunol, 20 (5), 413-24
PubMed 6209791

Bogen B (1984)
H-2 and non-H-2 genes complement each other for a carrier (idiotype)-specific Th response
Immunogenetics, 20 (4), 453-7
PubMed 6237990

Bogen B, Hannestad K (1984)
Specificity of antibody and helper T-cell responses to the isologous myeloma protein W3129 and its subunits
Mol Immunol, 21 (7), 653-61
PubMed 6205254

Bogen B, Hannestad K (1984)
Determinant-specific regulation of T helper cell responses to murine lambda light chains by both H-2 and non-H-2 genes
Eur J Immunol, 14 (2), 158-63
PubMed 6199213

Publications 1983

Bogen B, Jørgensen T, Hannestad K (1983)
Recognition of lambda 1 and lambda 2 murine light chains by carrier-specific isologous T helper cells; effect of L-H chain assembly
Eur J Immunol, 13 (5), 353-9
PubMed 6189725

Jørgensen T, Bogen B, Hannestad K (1983)
T helper cells recognize an idiotope located on peptide 88-114/117 of the light chain variable domain of an isologous myeloma protein (315)
J Exp Med, 158 (6), 2183-8
PubMed 6227679

Publications 1982

Marhaug G, Gaudernack G, Bogen B, Husby G (1982)
Monoclonal hybridoma antibodies to human amyloid related protein SAA
Clin Exp Immunol, 50 (2), 390-6
PubMed 7151332

Publications 1981

Myhre ES, Waldum HL, Burhol PG, Bogen B, Bostad L, Wesenberg F (1981)
[Acquired idiopathic hypogammaglobulinemia. A patient protocol]
Tidsskr Nor Laegeforen, 101 (7), 459-61
PubMed 7209936