Publications 2024

Hinke DM, Anderson AM, Katta K, Laursen MF, Tesfaye DY, Werninghaus IC, Angeletti D, Grødeland G, Bogen B, Braathen R (2024)
Applying valency-based immuno-selection to generate broadly cross-reactive antibodies against influenza hemagglutinins
Nat Commun, 15 (1), 850
DOI 10.1038/s41467-024-44889-w, PubMed 38346952

Publications 2023

Werninghaus IC, Hinke DM, Fossum E, Bogen B, Braathen R (2023)
Neuraminidase delivered as an APC-targeted DNA vaccine induces protective antibodies against influenza
Mol Ther, 31 (7), 2188-2205
DOI 10.1016/j.ymthe.2023.03.012, PubMed 36926694

Westhrin M, Blazevski J, Textor A, Abdollahi P, Gopalakrishnan RP, Ngo LT, Hofgaard PO, Heinzelbecker J, Bobic S, Fossum E, Spång HCL, Braathen R, Bogen B (2023)
Id-neoantigen vaccine induces therapeutic CD8⁺ T cells against multiple myeloma: H chain-loss escapees cause FLC MM
J Immunother Cancer, 11 (8)
DOI 10.1136/jitc-2023-006944, PubMed 37607769

Publications 2022

Hinke DM, Andersen TK, Gopalakrishnan RP, Skullerud LM, Werninghaus IC, Grødeland G, Fossum E, Braathen R, Bogen B (2022)
Antigen bivalency of antigen-presenting cell-targeted vaccines increases B cell responses
Cell Rep, 39 (9), 110901
DOI 10.1016/j.celrep.2022.110901, PubMed 35649357

Tesfaye DY, Bobic S, Lysén A, Huszthy PC, Gudjonsson A, Braathen R, Bogen B, Fossum E (2022)
Targeting Xcr1 on Dendritic Cells Rapidly Induce Th1-Associated Immune Responses That Contribute to Protection Against Influenza Infection
Front Immunol, 13, 752714
DOI 10.3389/fimmu.2022.752714, PubMed 35296089

Publications 2021

Bjerkan L, Visweswaran GRR, Gudjonsson A, Labbé GM, Quinkert D, Pattinson DJ, Spång HCL, Draper SJ, Bogen B, Braathen R (2021)
APC-Targeted DNA Vaccination Against Reticulocyte-Binding Protein Homolog 5 Induces Plasmodium falciparum-Specific Neutralizing Antibodies and T Cell Responses
Front Immunol, 12, 720550
DOI 10.3389/fimmu.2021.720550, PubMed 34733274

Publications 2020

Braathen R, Spång HCL, Hinke DM, Blazevski J, Bobic S, Fossum E, Bogen B (2020)
A DNA Vaccine That Encodes an Antigen-Presenting Cell-Specific Heterodimeric Protein Protects against Cancer and Influenza
Mol Ther Methods Clin Dev, 17, 378-392
DOI 10.1016/j.omtm.2020.01.007, PubMed 32128342

Fossum E, Tesfaye DY, Bobic S, Gudjonsson A, Braathen R, Lahoud MH, Caminschi I, Bogen B (2020)
Targeting Antigens to Different Receptors on Conventional Type 1 Dendritic Cells Impacts the Immune Response
J Immunol, 205 (3), 661-673
DOI 10.4049/jimmunol.1901119, PubMed 32591401

Lysén A, Braathen R, Gudjonsson A, Tesfaye DY, Bogen B, Fossum E (2020)
Author Correction: Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site
Sci Rep, 10 (1), 5944
DOI 10.1038/s41598-020-62688-3, PubMed 32231213

Publications 2019

Huszthy PC, Gopalakrishnan RP, Jacobsen JT, Haabeth OAW, Løset GÅ, Braathen R, Schenck K, Tveita AA, Munthe LA, Bogen B (2019)
B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells
Proc Natl Acad Sci U S A, 116 (51), 25850-25859
DOI 10.1073/pnas.1902836116, PubMed 31796587

Lysén A, Braathen R, Gudjonsson A, Tesfaye DY, Bogen B, Fossum E (2019)
Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site
Sci Rep, 9 (1), 1820
DOI 10.1038/s41598-018-38080-7, PubMed 30755656

Mahalunkar S, Yadav AS, Gorain M, Pawar V, Braathen R, Weiss S, Bogen B, Gosavi SW, Kundu GC (2019)
Functional design of pH-responsive folate-targeted polymer-coated gold nanoparticles for drug delivery and in vivo therapy in breast cancer
Int J Nanomedicine, 14, 8285-8302
DOI 10.2147/IJN.S215142, PubMed 31802866

Publications 2018

Anderson AM, Baranowska-Hustad M, Braathen R, Grodeland G, Bogen B (2018)
Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza
J Immunol, 200 (6), 2057-2066
DOI 10.4049/jimmunol.1701088, PubMed 29427414

Braathen R, Spång HCL, Lindeberg MM, Fossum E, Grødeland G, Fredriksen AB, Bogen B (2018)
The Magnitude and IgG Subclass of Antibodies Elicited by Targeted DNA Vaccines Are Influenced by Specificity for APC Surface Molecules
Immunohorizons, 2 (1), 38-53
DOI 10.4049/immunohorizons.1700038, PubMed 31022690

Publications 2012

Spång HC, Braathen R, Bogen B (2012)
Heterodimeric barnase-barstar vaccine molecules: influence of one versus two targeting units specific for antigen presenting cells
PLoS One, 7 (9), e45393
DOI 10.1371/journal.pone.0045393, PubMed 23028981

Publications 2009

Ghumra A, Shi J, Mcintosh RS, Rasmussen IB, Braathen R, Johansen FE, Sandlie I, Mongini PK, Areschoug T, Lindahl G, Lewis MJ, Woof JM, Pleass RJ (2009)
Structural requirements for the interaction of human IgM and IgA with the human Fcalpha/mu receptor
Eur J Immunol, 39 (4), 1147-56
DOI 10.1002/eji.200839184, PubMed 19266484

Publications 2008

Ghumra A, Semblat JP, McIntosh RS, Raza A, Rasmussen IB, Braathen R, Johansen FE, Sandlie I, Mongini PK, Rowe JA, Pleass RJ (2008)
Identification of residues in the Cmu4 domain of polymeric IgM essential for interaction with Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1)
J Immunol, 181 (3), 1988-2000
DOI 10.4049/jimmunol.181.3.1988, PubMed 18641336

Publications 2007

Braathen R, Hohman VS, Brandtzaeg P, Johansen FE (2007)
Secretory antibody formation: conserved binding interactions between J chain and polymeric Ig receptor from humans and amphibians
J Immunol, 178 (3), 1589-97
DOI 10.4049/jimmunol.178.3.1589, PubMed 17237408

Publications 2006

Braathen R (2006)
Structural motifs for the formation of secretory IgA and binding of non-Ig ligands by the polymeric Ig receptor
In Series of dissertations submitted to the Faculty of Medicine, University of Oslo, Unipub, Oslo, no. 382, 1 b. (flere pag.)
BIBSYS 060369221, ISBN 82-8072-675-6

Braathen R, Sandvik A, Berntzen G, Hammerschmidt S, Fleckenstein B, Sandlie I, Brandtzaeg P, Johansen FE, Lauvrak V (2006)
Identification of a polymeric Ig receptor binding phage-displayed peptide that exploits epithelial transcytosis without dimeric IgA competition
J Biol Chem, 281 (11), 7075-81
DOI 10.1074/jbc.M508509200, PubMed 16423833

Publications 2003

Elm C, Braathen R, Bergmann S, Frank R, Vaerman JP, Kaetzel CS, Chhatwal GS, Johansen FE, Hammerschmidt S (2003)
Ectodomains 3 and 4 of human polymeric Immunoglobulin receptor (hpIgR) mediate invasion of Streptococcus pneumoniae into the epithelium
J Biol Chem, 279 (8), 6296-304
DOI 10.1074/jbc.M310528200, PubMed 14660617

Publications 2002

Braathen R, Sorensen V, Brandtzaeg P, Sandlie I, Johansen FE (2002)
The carboxyl-terminal domains of IgA and IgM direct isotype-specific polymerization and interaction with the polymeric immunoglobulin receptor
J Biol Chem, 277 (45), 42755-62
DOI 10.1074/jbc.M205502200, PubMed 12213814

Publications 2001

Johansen FE, Braathen R, Brandtzaeg P (2001)
The J chain is essential for polymeric Ig receptor-mediated epithelial transport of IgA
J Immunol, 167 (9), 5185-92
DOI 10.4049/jimmunol.167.9.5185, PubMed 11673531

Publications 2000

Johansen FE, Braathen R, Brandtzaeg P (2000)
Role of J chain in secretory immunoglobulin formation
Scand J Immunol, 52 (3), 240-8
DOI 10.1046/j.1365-3083.2000.00790.x, PubMed 10972899

Publications 1999

Braathen R (1999)
A study on the structural basis for the different polymerization of IgA and IgM
R. Braathen, Oslo, 84 bl.
BIBSYS 991310861