Publications
Publications published since 2003 or in press from OUS - Laboratory for molecular biology
100 publications found
Publications in press
-
Phylogenetic Analysis of Human Immunodeficiency Virus type 1 (HIV-1) Subtype C Env gp 120 sequences among four drug naïve families following subsequent heterosexual and vertical transmissions
AIDS Res Hum Retroviruses (in press)
PubMed 22206228 -
AP endonuclease independent repair of abasic sites in Schizosaccharomyces pombe
Nucleic Acids Res (in press)
PubMed 22084197
Publications 2012
-
Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor
Nat Commun, 3, 610
PubMed 22215085 -
Lack of the DNA glycosylases MYH and OGG1 in the cancer prone double mutant mouse does not increase mitochondrial DNA mutagenesis
DNA Repair (Amst), 11 (3), 278-85
PubMed 22209780 -
DNA alkylation lesions and their repair in human cells: modification of the comet assay with 3-methyladenine DNA glycosylase (AlkD)
Toxicol Lett, 208 (1), 76-81
PubMed 22019460 -
Characterization of the Chitinolytic Machinery of Enterococcus faecalis V583 and High-Resolution Structure of Its Oxidative CBM33 Enzyme
J Mol Biol, 416 (2), 239-54
PubMed 22210154
Publications 2011
-
Caenorhabditis elegans NDX-4 is a MutT-type enzyme that contributes to genomic stability
DNA Repair (Amst), 10 (2), 176-87
PubMed 21111690 -
The molecular structure of tris-2,2,6,6-tetramethyl-heptane-3,5-dione aluminium: gas-phase electron diffraction, quantum chemical calculations and X-ray crystallography
Struct. Chem., 22 (2), 393-399 -
Separation-of-function mutants unravel the dual-reaction mode of human 8-oxoguanine DNA glycosylase
Structure, 19 (1), 117-27
PubMed 21220122 -
Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa
Hum Reprod, 26 (12), 3249-63
PubMed 21946930 -
The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication
Mol Microbiol, 79 (2), 433-46
PubMed 21219462 -
Schizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histones
PLoS One, 6 (9), e25188
PubMed 21949882 -
Schizosaccharomyces pombe encodes a mutated AP endonuclease 1
DNA Repair (Amst), 10 (3), 296-305
PubMed 21193357 -
Modeling the impact of mitochondrial DNA damage in forebrain neurons and beyond
Mech Ageing Dev, 132 (8-9), 424-8
PubMed 21354441 -
Incidence and outcomes of ganciclovir-resistant cytomegalovirus infections in 1244 kidney transplant recipients
Transplantation, 92 (2), 217-23
PubMed 21685829 -
Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia
Proc Natl Acad Sci U S A, 108 (46), 18802-7
PubMed 22065741 -
Mitochondrial DNA damage level determines neural stem cell differentiation fate
J Neurosci, 31 (26), 9746-51
PubMed 21715639 -
The ada operon of Mycobacterium tuberculosis encodes two DNA methyltransferases for inducible repair of DNA alkylation damage
DNA Repair (Amst), 10 (6), 595-602
PubMed 21570366 -
A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression
Proc Natl Acad Sci U S A, 108 (46), 18748-53
PubMed 22042866
Publications 2010
-
Autophagic degradation of an oncoprotein
Autophagy, 6 (7), 964-5
PubMed 20724820 -
Calprotectin (S100A8/S100A9) and Myeloperoxidase: Co-Regulators of Formation of Reactive Oxygen Species
Toxins (Basel), 2 (1), 95-115
PubMed 22069549 -
Reduced expression of DNA glycosylases in post-hypoxic newborn pigs undergoing therapeutic hypothermia
Brain Res, 1363, 198-205
PubMed 20883672 -
Antenatal HIV-1 RNA load and timing of mother to child transmission; a nested case-control study in a resource poor setting
Virol J, 7, 176
PubMed 20678190 -
L-isoleucyl-L-asparagine 1.094-hydrate: a hybrid hydrogen-bonding pattern
Acta Crystallogr C, 66 (Pt 7), o349-52
PubMed 20603563 -
Pseudoracemic amino acid complexes: blind predictions for flexible two-component crystals
Phys Chem Chem Phys, 12 (30), 8466-77
PubMed 20461256 -
Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein
Blood, 116 (13), 2324-31
PubMed 20574048 -
Subcellular distribution of nuclear import-defective isoforms of the promyelocytic leukemia protein
BMC Mol Biol, 11, 89
PubMed 21092142 -
Tiling array analysis of UV treated Escherichia coli predicts novel differentially expressed small peptides
PLoS One, 5 (12), e15356
PubMed 21203457 -
Mitochondrial DNA integrity is essential for mitochondrial maturation during differentiation of neural stem cells
Stem Cells, 28 (12), 2195-204
PubMed 20954243
Publications 2009
-
Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair
Nat Struct Mol Biol, 16 (2), 138-43
PubMed 19136958 -
DNA base repair--recognition and initiation of catalysis
FEMS Microbiol Rev, 33 (6), 1044-78
PubMed 19659577 -
Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma
Carcinogenesis, 30 (7), 1147-54
PubMed 19443904 -
Modulation of DNA glycosylase activities in mesenchymal stem cells
Exp Cell Res, 315 (15), 2558-67
PubMed 19477173 -
Expression patterns of Neil3 during embryonic brain development and neoplasia
BMC Neurosci, 10, 45
PubMed 19426544 -
Molecular requirements for sorting of the chemokine interleukin-8/CXCL8 to endothelial Weibel-Palade bodies
J Biol Chem, 284 (35), 23532-9
PubMed 19578117 -
The Saccharomyces cerevisiae Rad6 postreplication repair and Siz1/Srs2 homologous recombination-inhibiting pathways process DNA damage that arises in asf1 mutants
Mol Cell Biol, 29 (19), 5226-37
PubMed 19635810 -
Expression and purification of NEIL3, a human DNA glycosylase homolog
Protein Expr Purif, 65 (2), 160-4
PubMed 19121397 -
Inhibition of canonical Wnt signaling promotes gliogenesis in P0-NSCs
Biochem Biophys Res Commun, 386 (4), 628-33
PubMed 19545542 -
The carotenoid beta-cryptoxanthin stimulates the repair of DNA oxidation damage in addition to acting as an antioxidant in human cells
Carcinogenesis, 30 (2), 308-14
PubMed 19056931 -
Characterization of the major formamidopyrimidine-DNA glycosylase homolog in Mycobacterium tuberculosis and its linkage to variable tandem repeats
FEMS Immunol Med Microbiol, 56 (2), 151-61
PubMed 19496823 -
Accumulation of 8-oxoguanine in liver DNA during hyperoxic resuscitation of newborn mice
Pediatr Res, 66 (5), 533-8
PubMed 19668103 -
DNA binding kinetics of two response regulators, PlnC and PlnD, from the bacteriocin regulon of Lactobacillus plantarum C11
BMC Biochem, 10, 17
PubMed 19519894 -
Nimotuzumab, an antitumor antibody that targets the epidermal growth factor receptor, blocks ligand binding while permitting the active receptor conformation
Cancer Res, 69 (14), 5851-9
PubMed 19584289 -
Up-regulation of myocardial DNA base excision repair activities in experimental heart failure
Mutat Res, 666 (1-2), 32-8
PubMed 19481677
Publications 2008
-
Bacteriocins (meningocins) in Norwegian isolates of Neisseria meningitidis: possible role in the course of a meningococcal epidemic
APMIS, 116 (5), 333-44
PubMed 18452423 -
Dissection of the molecular defects caused by pathogenic mutations in the DNA repair factor XPC
Mol Cell Biol, 28 (23), 7225-35
PubMed 18809580 -
DNA apurinic-apyrimidinic site binding and excision by endonuclease IV
Nat Struct Mol Biol, 15 (5), 515-22
PubMed 18408731 -
Prevalence of reverse transcriptase and protease mutations associated with antiretroviral drug resistance among drug-naïve HIV-1 infected pregnant women in Kagera and Kilimanjaro regions, Tanzania
AIDS Res Ther, 5, 13
PubMed 18570675 -
Diversity of human immunodeficiency virus type 1 subtypes in Kagera and Kilimanjaro regions, Tanzania
AIDS Res Hum Retroviruses, 24 (6), 761-9
PubMed 18507522 -
Evolution of human immunodeficiency virus type 1 serotypes in northern Tanzania: a retrospective study
APMIS, 116 (6), 507-14
PubMed 18754325 -
Characterization of human cytomegalovirus uracil DNA glycosylase (UL114) and its interaction with polymerase processivity factor (UL44)
J Mol Biol, 381 (2), 276-88
PubMed 18599070 -
Widespread distribution of DNA glycosylases removing oxidative DNA lesions in human and rodent brains
DNA Repair (Amst), 7 (9), 1578-88
PubMed 18603019 -
Base excision repair activities in organotypic hippocampal slice cultures exposed to oxygen and glucose deprivation
DNA Repair (Amst), 7 (6), 869-78
PubMed 18406215 -
Overexpression of the LexA-regulated tisAB RNA in E. coli inhibits SOS functions; implications for regulation of the SOS response
Nucleic Acids Res, 36 (19), 6249-59
PubMed 18832374
Publications 2007
-
The outer membrane secretin PilQ from Neisseria meningitidis binds DNA
Microbiology, 153 (Pt 5), 1593-603
PubMed 17464074 -
Structural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeats
Nucleic Acids Res, 35 (7), 2451-9
PubMed 17395642 -
Genetic interactions of DNA repair pathways in the pathogen Neisseria meningitidis
J Bacteriol, 189 (15), 5728-37
PubMed 17513474 -
Repair of methyl lesions in DNA and RNA by oxidative demethylation
Neuroscience, 145 (4), 1222-32
PubMed 17175108 -
The capacity to remove 8-oxoG is enhanced in newborn neural stem/progenitor cells and decreases in juvenile mice and upon cell differentiation
DNA Repair (Amst), 6 (6), 723-32
PubMed 17236821 -
Human NEIL1 localizes with the centrosomes and condensed chromosomes during mitosis
DNA Repair (Amst), 6 (10), 1425-33
PubMed 17556049 -
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells
Nature, 447 (7143), 447-52
PubMed 17450122 -
Computational prediction of the effects of non-synonymous single nucleotide polymorphisms in human DNA repair genes
Neuroscience, 145 (4), 1273-9
PubMed 17055652
Publications 2006
-
A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD
Mol Microbiol, 59 (5), 1602-9
PubMed 16468998 -
New functions of XPC in the protection of human skin cells from oxidative damage
EMBO J, 25 (18), 4305-15
PubMed 16957781 -
Crystal structure and enzymatic properties of a bacterial family 19 chitinase reveal differences from plant enzymes
FEBS J, 273 (21), 4889-900
PubMed 17010167 -
Repair and mutagenesis at oxidized DNA lesions in the developing brain of wild-type and Ogg1-/- mice
Oncogene, 25 (17), 2425-32
PubMed 16369492 -
Human cytomegalovirus infection modulates DNA base excision repair in fibroblast cells
Virology, 348 (2), 389-97
PubMed 16476462 -
Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage
EMBO J, 25 (14), 3389-97
PubMed 16858410 -
18S rDNA polymerase chain reaction and sequencing in onychomycosis diagnostics
Acta Derm Venereol, 86 (3), 223-6
PubMed 16710579
Publications 2005
-
Biochemical characterization and DNA repair pathway interactions of Mag1-mediated base excision repair in Schizosaccharomyces pombe
Nucleic Acids Res, 33 (3), 1123-31
PubMed 15722486 -
Impaired base excision repair and accumulation of oxidative base lesions in CD4+ T cells of HIV-infected patients
Blood, 105 (12), 4730-5
PubMed 15705786 -
Antimutator role of DNA glycosylase MutY in pathogenic Neisseria species
J Bacteriol, 187 (8), 2801-9
PubMed 15805527 -
Modulatory effect of mannose-binding lectin on cytokine responses: possible roles in HIV infection
Eur J Clin Invest, 35 (12), 765-70
PubMed 16313253 -
1.6-Angstroms crystal structure of EntA-im. A bacterial immunity protein conferring immunity to the antimicrobial activity of the pediocin-like bacteriocin enterocin A
J Biol Chem, 280 (19), 19045-50
PubMed 15753083 -
Dynamic relocalization of hOGG1 during the cell cycle is disrupted in cells harbouring the hOGG1-Cys326 polymorphic variant
Nucleic Acids Res, 33 (6), 1813-24
PubMed 15800211 -
Product inhibition and magnesium modulate the dual reaction mode of hOgg1
DNA Repair (Amst), 4 (3), 381-7
PubMed 15661661 -
Genomic sequence correction by single-stranded DNA oligonucleotides: role of DNA synthesis and chemical modifications of the oligonucleotide ends
J Gene Med, 7 (12), 1534-44
PubMed 16025558 -
Predicting non-coding RNA genes in Escherichia coli with boosted genetic programming
Nucleic Acids Res, 33 (10), 3263-70
PubMed 15942029
Publications 2004
-
A general role of the DNA glycosylase Nth1 in the abasic sites cleavage step of base excision repair in Schizosaccharomyces pombe
Nucleic Acids Res, 32 (17), 5119-25
PubMed 15452279 -
Biased distribution of DNA uptake sequences towards genome maintenance genes
Nucleic Acids Res, 32 (3), 1050-8
PubMed 14960717 -
Substrate specificities of bacterial and human AlkB proteins
Nucleic Acids Res, 32 (11), 3456-61
PubMed 15229293 -
Increased expression of toll-like receptor 2 on monocytes in HIV infection: possible roles in inflammation and viral replication
Clin Infect Dis, 39 (2), 264-9
PubMed 15307037 -
AlkB restores the biological function of mRNA and tRNA inactivated by chemical methylation
Mol Cell, 16 (1), 107-16
PubMed 15469826 -
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro
Mol Cell Biol, 24 (18), 8195-209
PubMed 15340079 -
Transformation and DNA repair: linkage by DNA recombination
Trends Microbiol, 12 (1), 1-4
PubMed 14700543 -
Base J, found in nuclear DNA of Trypanosoma brucei, is not a target for DNA glycosylases
DNA Repair (Amst), 3 (2), 145-54
PubMed 14706348 -
The Bacillus subtilis counterpart of the mammalian 3-methyladenine DNA glycosylase has hypoxanthine and 1,N6-ethenoadenine as preferred substrates
J Biol Chem, 279 (14), 13601-6
PubMed 14729667
Publications 2003
-
Influence of DNA torsional rigidity on excision of 7,8-dihydro-8-oxo-2'-deoxyguanosine in the presence of opposing abasic sites by human OGG1 protein
Nucleic Acids Res, 31 (7), 1897-903
PubMed 12655006 -
WRN interacts physically and functionally with the recombination mediator protein RAD52
J Biol Chem, 278 (38), 36476-86
PubMed 12750383 -
Mutagenicity, toxicity and repair of DNA base damage induced by oxidation
Mutat Res, 531 (1-2), 37-80
PubMed 14637246 -
Comparative analysis of 8-oxoG:C, 8-oxoG:A, A:C and C:C DNA repair in extracts from wild type or 8-oxoG DNA glycosylase deficient mammalian and bacterial cells
DNA Repair (Amst), 2 (6), 707-18
PubMed 12767349 -
Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage
Mol Cell Biol, 23 (15), 5346-53
PubMed 12861020 -
The effects of a growth-inhibiting tripeptide, acetylGlu-Ser-GlyNH2 (Ac-ESG), on gene expression and cell cycle progression of two lymphoma cell lines
Anticancer Res, 23 (4), 3159-65
PubMed 12926049 -
Base excision repair activities required for yeast to attain a full chronological life span
Aging Cell, 2 (2), 93-104
PubMed 12882322 -
Incision at hypoxanthine residues in DNA by a mammalian homologue of the Escherichia coli antimutator enzyme endonuclease V
Nucleic Acids Res, 31 (14), 3893-900
PubMed 12853604 -
Limited repair of 8-hydroxy-7,8-dihydroguanine residues in human testicular cells
Nucleic Acids Res, 31 (4), 1351-63
PubMed 12582255 -
A new Schizosaccharomyces pombe base excision repair mutant, nth1, reveals overlapping pathways for repair of DNA base damage
Mol Microbiol, 48 (2), 465-80
PubMed 12675805 -
Better late than never for repair of miscoding lesions within a transcribed template
Mol Cell, 12 (4), 799-800
PubMed 14580331 -
Normal somatic hypermutation of Ig genes in the absence of 8-hydroxyguanine-DNA glycosylase
J Immunol, 170 (11), 5558-62
PubMed 12759433 -
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA
Nature, 421 (6925), 859-63
PubMed 12594517




Go back
Print this page
E-mail this page
