Publications
Publications published since 1971 or in press from OUS - Department of Biochemistry
818 publications found
Publications in press
-
A new family of proteins related to the HEAT-like repeat DNA glycosylases with affinity for branched DNA structures
J Struct Biol (in press)
PubMed 23623903 -
Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties
J Control Release, 168 (3), 317-326 (in press)
PubMed 23567040 -
Death of multiple myeloma cells induced by cAMP-signaling involves downregulation of Mcl-1 via the JAK/STAT pathway
Cancer Lett (in press)
PubMed 23454584 -
SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking
Oncogene (in press)
PubMed 23222715 -
The ERM Proteins Ezrin and Moesin Regulate Retrograde Shiga Toxin Transport
Traffic (in press)
PubMed 23593995 -
Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
Biochim Biophys Acta (in press)
PubMed 23623766 -
Flotillins as regulators of ErbB2 levels in breast cancer
Oncogene (in press)
PubMed 22869152 -
Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic
FEBS J (in press)
PubMed 23289851 -
ESCRTing autophagic clearance of aggregating proteins
Autophagy, 4 (2) (in press)
PubMed 18204305 -
FE65 regulates and interacts with the Bloom syndrome protein in dynamic nuclear spheres - potential relevance to Alzheimer's disease
J Cell Sci (in press)
PubMed 23572515
Publications 2013
-
Myotubularin and PtdIns3P remodel the sarcoplasmic reticulum in muscle in vivo
J Cell Sci, 126 (Pt 8), 1806-19
PubMed 23444364 -
The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions during Autophagy
Dev Cell, 25 (1), 15-28
PubMed 23562278 -
OikoBase: a genomics and developmental transcriptomics resource for the urochordate Oikopleura dioica
Nucleic Acids Res, 41 (Database issue), D845-53
PubMed 23185044 -
NBR1 acts as an autophagy receptor for peroxisomes
J Cell Sci, 126 (Pt 4), 939-52
PubMed 23239026 -
Spatiotemporal control of Cindr at ring canals during incomplete cytokinesis in the Drosophila male germline
Dev Biol, 377 (1), 9-20
PubMed 23499247 -
FAK regulates Cdk2 in EGF-stimulated primary cultures of hepatocytes
J Cell Physiol, 228 (6), 1304-13
PubMed 23168795 -
BiP Negatively Affects Ricin Transport
Toxins (Basel), 5 (5), 969-82
PubMed 23666197 -
Exosomal miRNAs as Biomarkers for Prostate Cancer
Front Genet, 4, 36
PubMed 23519132 -
Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene ?-catenin
EMBO Rep, 14 (1), 10-1
PubMed 23229585 -
Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration
EMBO Rep, 14 (1), 57-64
PubMed 23154468 -
Alternariol induces abnormal nuclear morphology and cell cycle arrest in murine RAW 264.7 macrophages
Toxicol Lett, 219 (1), 8-17
PubMed 23454835 -
ERK-mediated phosphorylation of fibroblast growth factor receptor 1 on Ser777 inhibits signaling
Sci Signal, 6 (262), ra11
PubMed 23405013
Publications 2012
-
Ubiquitination and phosphorylation of Beclin 1 and its binding partners: Tuning class III phosphatidylinositol 3-kinase activity and tumor suppression
FEBS Lett, 586 (11), 1584-91
PubMed 22673570 -
Highly potent inhibitors of proprotein convertase furin as potential drugs for treatment of infectious diseases
J Biol Chem, 287 (26), 21992-2003
PubMed 22539349 -
Shiga toxins
Toxicon, 60 (6), 1085-107
PubMed 22960449 -
Inhibitors of intravesicular acidification protect against Shiga toxin in a pH-independent manner
Traffic, 13 (3), 443-54
PubMed 22132807 -
Benfotiamine increases glucose oxidation and downregulates NADPH oxidase 4 expression in cultured human myotubes exposed to both normal and high glucose concentrations
Genes Nutr, 7 (3), 459-69
PubMed 21984258 -
Smad ubiquitination regulatory factor-2 controls gap junction intercellular communication by modulating endocytosis and degradation of connexin43
J Cell Sci, 125 (Pt 17), 3966-76
PubMed 22623726 -
The AAA-type ATPases Pex1p and Pex6p and their role in peroxisomal matrix protein import in Saccharomyces cerevisiae
Biochim Biophys Acta, 1823 (1), 150-8
PubMed 21963882 -
Importance of agglomeration state and exposure conditions for uptake and pro-inflammatory responses to amorphous silica nanoparticles in bronchial epithelial cells
Nanotoxicology, 6 (7), 700-12
PubMed 21793771 -
The role of ubiquitylation in receptor endocytosis and endosomal sorting
J Cell Sci, 125 (Pt 2), 265-75
PubMed 22357968 -
Leupeptin enhances cell surface localization of fibroblast growth factor receptor 1 in adult sensory neurons by increased recycling
Eur J Cell Biol, 91 (2), 129-38
PubMed 22169219 -
The liver X receptor modulator 22(S)-hydroxycholesterol exerts cell-type specific effects on lipid and glucose metabolism
J Steroid Biochem Mol Biol, 128 (3-5), 154-64
PubMed 22051079 -
Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells
Biochim Biophys Acta, 1819 (11-12), 1154-63
PubMed 22982408 -
Genetic blockage of endocytic pathways reveals differences in the intracellular processing of non-viral gene delivery systems
J Control Release, 163 (3), 385-95
PubMed 23041276 -
Uptake of ricinB-quantum dot nanoparticles by a macropinocytosis-like mechanism
J Nanobiotechnology, 10, 33
PubMed 22849338 -
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation
PLoS Biol, 10 (12), e1001450
PubMed 23271954 -
Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy, 8 (4), 445-544
PubMed 22966490 -
The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain
J Cell Sci, 125 (Pt 1), 29-36
PubMed 22266905 -
Selective autophagy in Drosophila
Int J Cell Biol, 2012, 146767
PubMed 22567011 -
p62 at the interface of autophagy, oxidative stress signaling, and cancer
Antioxid Redox Signal, 17 (5), 786-93
PubMed 22074114 -
Effect of cycloheximide on epidermal growth factor receptor trafficking and signaling
FEBS Lett, 586 (20), 3575-81
PubMed 22971756 -
The PtdIns3P-binding protein Phafin 2 mediates epidermal growth factor receptor degradation by promoting endosome fusion
Traffic, 13 (11), 1547-63
PubMed 22816767 -
Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1
Biochem J, 441 (1), 399-406
PubMed 21936852 -
Shaping development with ESCRTs
Nat Cell Biol, 14 (1), 38-45
PubMed 22193162 -
The oncoprotein ErbB3 is endocytosed in the absence of added ligand in a clathrin-dependent manner
Carcinogenesis, 33 (5), 1031-9
PubMed 22436610 -
Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3
Mol Cell Proteomics, 11 (7), M111.012914
PubMed 22457534 -
Studies of ribonucleotide reductase in crucian carp-an oxygen dependent enzyme in an anoxia tolerant vertebrate
PLoS One, 7 (8), e42784
PubMed 22916159 -
BC4707 is a major facilitator superfamily multidrug resistance transport protein from Bacillus cereus implicated in fluoroquinolone tolerance
PLoS One, 7 (5), e36720
PubMed 22615800 -
Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome
Int J Cancer, 131 (3), 570-81
PubMed 21866551 -
The fusion of early endosomes induces molecular-motor-driven tubule formation and fission
J Cell Sci, 125 (Pt 8), 1910-9
PubMed 22357949 -
Molecular imaging: challenges of bringing imaging of intracellular targets into common clinical use
Contrast Media Mol Imaging, 7 (1), 1-6
PubMed 22344874 -
The Rabs: a family at the root of metazoan evolution
BMC Biol, 10, 68
PubMed 22873178 -
Characterization of liposarcoma cell lines for preclinical and biological studies
Sarcoma, 2012, 148614
PubMed 22911243 -
FGF1-gold nanoparticle conjugates targeting FGFR efficiently decrease cell viability upon NIR irradiation
Int J Nanomedicine, 7, 5915-27
PubMed 23226697 -
Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin
PLoS One, 7 (7), e40429
PubMed 22792315 -
A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice
Cancer Res, 72 (11), 2822-32
PubMed 22440753 -
Nuclear import of exogenous FGF1 requires the ER-protein LRRC59 and the importins Kpn?1 and Kpn?1
Traffic, 13 (5), 650-64
PubMed 22321063 -
Doping analyses are not on safe ground
Tidsskr Nor Laegeforen, 132 (8), 929-30
PubMed 22562317
Publications 2011
-
Cell biology. Growth signaling from inside
Science, 334 (6056), 611-2
PubMed 22053037 -
p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects
Autophagy, 7 (6), 572-83
PubMed 21325881 -
Preconceptional paternal glycidamide exposure affects embryonic gene expression: single embryo gene expression study following in vitro fertilization
Reprod Toxicol, 32 (4), 463-71
PubMed 21978862 -
Marasmius oreades agglutinin (MOA) is a chimerolectin with proteolytic activity
Biochem Biophys Res Commun, 408 (3), 405-10
PubMed 21513701 -
Derlin-dependent retrograde transport from endosomes to the Golgi apparatus
Traffic, 12 (10), 1417-31
PubMed 21722281 -
Shiga toxin and its use in targeted cancer therapy and imaging
Microb Biotechnol, 4 (1), 32-46
PubMed 21255370 -
Septation of infectious hyphae is critical for appressoria formation and virulence in the smut fungus Ustilago maydis
PLoS Pathog, 7 (5), e1002044
PubMed 21625538 -
The phosphoinositide 3-kinase Vps34p is required for pexophagy in Saccharomyces cerevisiae
Biochem J, 434 (1), 161-70
PubMed 21121900 -
Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development
Commun Integr Biol, 4 (1), 1-9
PubMed 21509167 -
Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling
PLoS One, 6 (7), e21708
PubMed 21779335 -
Molecular mechanisms of ubiquitin-dependent membrane traffic
Annu Rev Biophys, 40, 119-42
PubMed 21332354 -
Nanoparticles hinder intracellular transport
Trac-Trends Anal. Chem., 30 (10), VII-VIII -
Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies
Nano Today, 6 (2), 176-185 -
The driver of malignancy in KG-1a leukemic cells, FGFR1OP2-FGFR1, encodes an HSP90 addicted oncoprotein
Cell Signal, 23 (11), 1758-66
PubMed 21745565 -
Role of phospholipase A(2) in retrograde transport of ricin
Toxins (Basel), 3 (9), 1203-19
PubMed 22069763 -
Invariant chain increases the half-life of MHC II by delaying endosomal maturation
Immunol Cell Biol, 89 (5), 619-29
PubMed 21116285 -
SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
Oncogene, 30 (37), 3967-78
PubMed 21499309 -
Cell polarity and migration: emerging role for the endosomal sorting machinery
Physiology (Bethesda), 26 (3), 171-80
PubMed 21670163 -
Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting
Traffic, 12 (9), 1211-26
PubMed 21564451 -
Basic and discovery-based translational research on cancer was on the agenda at the 21st Congress of the European Association for Cancer Research (EACR) in Oslo, Norway, 26-29 June 2010
Clin. Transl. Oncol., 13 (1), 1-2 -
Histone variant innovation in a rapidly evolving chordate lineage
BMC Evol Biol, 11, 208
PubMed 21756361 -
Does venous insufficiency impair the exercise-induced rise in arterial leg blood flow?
Phlebology, 26 (8), 326-31
PubMed 21937517 -
Does the great saphenous vein stripping improve arterial leg blood flow during exercise?
Eur J Vasc Endovasc Surg, 41 (5), 697-703
PubMed 21376644 -
Endocytosis and signaling
Curr Opin Cell Biol, 23 (4), 393-403
PubMed 21474295 -
Cell biology. A helix for the final cut
Science, 331 (6024), 1533-4
PubMed 21436431 -
CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor
Exp Cell Res, 317 (13), 1804-16
PubMed 21635887 -
A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
PLoS One, 6 (3), e17086
PubMed 21455500 -
Clathrin-independent endocytosis: mechanisms and function
Curr Opin Cell Biol, 23 (4), 413-20
PubMed 21466956 -
Cell differentiation: midbody remnants - junk or fate factors?
Curr Biol, 21 (23), R958-60
PubMed 22153165 -
Comment on "short ligands affect modes of QD uptake and elimination in human cells"
ACS Nano, 5 (10), 7690; author reply 7691-2
PubMed 22023400 -
A single point mutation in ricin A-chain increases toxin degradation and inhibits EDEM1-dependent ER retrotranslocation
Biochem J, 436 (2), 371-85
PubMed 21388347 -
The genome sequence of Atlantic cod reveals a unique immune system
Nature, 477 (7363), 207-10
PubMed 21832995 -
Harald Stenmark: hands on FYVE-fingers. Interview by Caitlin Sedwick
J Cell Biol, 192 (4), 544-5
PubMed 21339328 -
Liposarcoma Cells with Aldefluor and CD133 Activity have a Cancer Stem Cell Potential
Clin Sarcoma Res, 1 (1), 8
PubMed 22612877 -
Ligand-induced downregulation of TrkA is partly regulated through ubiquitination by Cbl
FEBS Lett, 585 (12), 1741-7
PubMed 21570973 -
Protein C mutation (A267T) results in ER retention and unfolded protein response activation
PLoS One, 6 (8), e24009
PubMed 21901152 -
Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells
FEMS Immunol Med Microbiol, 61 (1), 63-75
PubMed 21054580 -
cAMP induces autophagy via a novel pathway involving ERK, cyclin E and Beclin 1
Autophagy, 7 (10), 1199-211
PubMed 21750416 -
Splenic marginal zone lymphoma with VH1-02 gene rearrangement expresses poly- and self-reactive antibodies with similar reactivity
Blood, 118 (12), 3331-9
PubMed 21725051 -
ESCRT proteins and cell signalling
Traffic, 12 (10), 1291-7
PubMed 21518165 -
Fibroblast growth factors and their receptors in cancer
Biochem J, 437 (2), 199-213
PubMed 21711248 -
Translocation of exogenous FGF1 into cytosol and nucleus is a periodic event independent of receptor kinase activity
Exp Cell Res, 317 (7), 1005-15
PubMed 21223966
Publications 2010
-
Protein secretion: unconventional exit by exophagy
Curr Biol, 20 (9), R415-8
PubMed 20462486 -
Cross talk between phosphatidylinositol 3-kinase and cyclic AMP (cAMP)-protein kinase a signaling pathways at the level of a protein kinase B/beta-arrestin/cAMP phosphodiesterase 4 complex
Mol Cell Biol, 30 (7), 1660-72
PubMed 20086095 -
p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
Autophagy, 6 (3), 330-44
PubMed 20168092 -
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy
Mol Cell, 38 (2), 265-79
PubMed 20417604 -
An inhibitory role of the G-protein regulator AGS3 in mTOR-dependent macroautophagy
PLoS One, 5 (1), e8877
PubMed 20126274 -
Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster
Curr Biol, 20 (10), 944-50
PubMed 20451383 -
Intracellular Mycobacterium avium intersect transferrin in the Rab11(+) recycling endocytic pathway and avoid lipocalin 2 trafficking to the lysosomal pathway
J Infect Dis, 201 (5), 783-92
PubMed 20121435 -
Control of Notch-ligand endocytosis by ligand-receptor interaction
J Cell Sci, 123 (Pt 17), 2931-42
PubMed 20720151 -
Roles of fibroblast growth factor receptors in carcinogenesis
Mol Cancer Res, 8 (11), 1439-52
PubMed 21047773 -
The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes
Immunity, 33 (4), 583-96
PubMed 20933442 -
Sialic acid-binding dwarf elder four-chain lectin displays nucleic acid N-glycosidase activity
Biochimie, 92 (1), 71-80
PubMed 19799962 -
UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
Autophagy, 6 (7), 863-70
PubMed 20724836 -
PI3K-AKT-mTOR pathway is dominant over androgen receptor signaling in prostate cancer cells
Cell Oncol, 32 (1-2), 11-27
PubMed 20203370 -
Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes
Dev Cell, 19 (1), 148-59
PubMed 20643357 -
Ubiquitination of ?-integrin cytoplasmic tails
Commun Integr Biol, 3 (6), 583-5
PubMed 21331246 -
Autophagy and its physiological relevance in arthropods: current knowledge and perspectives
Autophagy, 6 (5), 575-88
PubMed 20458176 -
Divide and ProsPer: the emerging role of PtdIns3P in cytokinesis
Trends Cell Biol, 20 (11), 642-9
PubMed 20880709 -
Autophagy as a trigger for cell death: autophagic degradation of inhibitor of apoptosis dBruce controls DNA fragmentation during late oogenesis in Drosophila
Autophagy, 6 (8), 1214-5
PubMed 20935512 -
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
J Cell Biol, 190 (4), 523-31
PubMed 20713604 -
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
J Cell Biol, 188 (2), 253-69
PubMed 20100911 -
Clostridium botulinum C2 toxin is internalized by clathrin- and Rho-dependent mechanisms
Cell Microbiol, 12 (12), 1809-20
PubMed 20690924 -
Interplay between toxin transport and flotillin localization
PLoS One, 5 (1), e8844
PubMed 20107503 -
ESCRT & Co
Biol Cell, 102 (5), 293-318
PubMed 20222872 -
p62, an autophagy hero or culprit?
Nat Cell Biol, 12 (3), 207-9
PubMed 20190829 -
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
Nat Cell Biol, 12 (4), 362-71
PubMed 20208530 -
Cytokinesis and cancer
FEBS Lett, 584 (12), 2652-61
PubMed 20371245 -
Cytokinesis and cancer (vol 584, pg 2652, 2010)
FEBS Lett., 584 (18), 4128 -
Endocytosis and retrograde transport of Shiga toxin
Toxicon, 56 (7), 1181-5
PubMed 19951719 -
Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine
FEBS Lett, 584 (12), 2626-34
PubMed 20385131 -
CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice
EMBO J, 29 (14), 2421-32
PubMed 20551902 -
New metal-based nanoparticles for intravenous use: requirements for clinical success with focus on medical imaging
Nanomedicine, 6 (6), 730-7
PubMed 20570639 -
The Sir Hans Krebs Lecture. How a lipid mediates tumour suppression. Delivered on 29 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden
FEBS J, 277 (23), 4837-48
PubMed 20977678 -
Time-resolved ultrastructural detection of phosphatidylinositol 3-phosphate
J Histochem Cytochem, 58 (11), 1025-32
PubMed 20713985 -
Activation of the ustilagic acid biosynthesis gene cluster in Ustilago maydis by the C2H2 zinc finger transcription factor Rua1
Appl Environ Microbiol, 76 (8), 2633-40
PubMed 20173069 -
A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
Exp Cell Res, 316 (20), 3368-78
PubMed 20643123 -
Functional characterization of the protein C A267T mutation: evidence for impaired secretion due to defective intracellular transport
BMC Cell Biol, 11, 67
PubMed 20815936 -
The Intracellular Journey of Shiga Toxins
The Open Toxinology Journal, 3, 3-12
PublikaID 24 -
Shiga toxin increases formation of clathrin-coated pits through Syk kinase
PLoS One, 5 (7), e10944
PubMed 20668539 -
Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5
Histochem Cell Biol, 133 (1), 41-55
PubMed 19830447
Publications 2009
-
Monitoring autophagic degradation of p62/SQSTM1
Methods Enzymol, 452, 181-97
PubMed 19200883 -
Autophagy in tumour suppression and promotion
Mol Oncol, 3 (4), 366-75
PubMed 19559660 -
Sorting nexin 8 regulates endosome-to-Golgi transport
Biochem Biophys Res Commun, 390 (1), 109-14
PubMed 19782049 -
Ligand-specific induction of endocytosis in taste receptor cells
J Exp Biol, 212 (Pt 1), 42-9
PubMed 19088209 -
Retinoic acid regulates Fas-induced apoptosis in Jurkat T cells: reversal of mitogen-mediated repression of Fas DISC assembly
J Leukoc Biol, 85 (3), 469-80
PubMed 19112091 -
Quantum dot bioconjugates: uptake into cells and induction of changes in normal cellular transport
San Jose, CA, USA, SPIE, 1, 7189[1], 71890T-9
PublikaID 29 -
Quantum dot bioconjugates: Uptake into cells and induction of changes in normal cellular transport
P SOC PHOTO-OPT INS, 7189, 71890T -
Cyclophilin A facilitates translocation of the Clostridium botulinum C2 toxin across membranes of acidified endosomes into the cytosol of mammalian cells
Cell Microbiol, 11 (5), 780-95
PubMed 19159389 -
Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
J Cell Sci, 122 (Pt 21), 3883-93
PubMed 19808888 -
ESCRTing membrane deformation
Cell, 136 (1), 15-7
PubMed 19135881 -
Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy
Autophagy, 5 (3), 298-302
PubMed 19066465 -
Expression of epidermal growth factor receptor or ErbB3 facilitates geldanamycin-induced down-regulation of ErbB2
Mol Cancer Res, 7 (2), 275-84
PubMed 19208749 -
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
Nature, 458 (7237), 445-52
PubMed 19325624 -
Disruption of Vps4 and JNK function in Drosophila causes tumour growth
PLoS One, 4 (2), e4354
PubMed 19194501 -
The role of ESCRT proteins in attenuation of cell signalling
Biochem Soc Trans, 37 (Pt 1), 137-42
PubMed 19143618 -
Dual degradation mechanisms ensure disposal of NHE6 mutant protein associated with neurological disease
Exp Cell Res, 315 (17), 3014-27
PubMed 19619532 -
How do ESCRT proteins control autophagy?
J Cell Sci, 122 (Pt 13), 2179-83
PubMed 19535733 -
Glycosphingolipid requirements for endosome-to-Golgi transport of Shiga toxin
Traffic, 10 (7), 868-82
PubMed 19453975 -
SNX4 in complex with clathrin and dynein: implications for endosome movement
PLoS One, 4 (6), e5935
PubMed 19529763 -
?-arrestins attenuate p38-mediated endosome to Golgi transport
Cell Microbiol, 11 (5), 796-807
PubMed 19159388 -
Seeing is believing
Nat Rev Mol Cell Biol, 10 (9), 582
PubMed 19702012 -
Rab GTPases as coordinators of vesicle traffic
Nat Rev Mol Cell Biol, 10 (8), 513-25
PubMed 19603039 -
ESCRT proteins in physiology and disease
Exp Cell Res, 315 (9), 1619-26
PubMed 19013455 -
Multivesicular endosome biogenesis in the absence of ESCRTs
Traffic, 10 (7), 925-37
PubMed 19490536 -
Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants
J Cell Sci, 122 (Pt 14), 2413-23
PubMed 19571114 -
Characterization of clathrin and Syk interaction upon Shiga toxin binding
Cell Signal, 21 (7), 1161-8
PubMed 19289168 -
Increased protein stability of FGF1 can compensate for its reduced affinity for heparin
J Biol Chem, 284 (37), 25388-403
PubMed 19574212 -
Size limitation in translocation of fibroblast growth factor 1 fusion proteins across the endosomal membrane
Biochemistry, 48 (30), 7209-18
PubMed 19558187 -
The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway
J Immunol, 183 (9), 5909-16
PubMed 19812211
Publications 2008
-
Cell-cycle-dependent binding kinetics for the early endosomal tethering factor EEA1
EMBO Rep, 9 (2), 171-8
PubMed 18188183 -
Quantitative analysis of autophagic activity in Drosophila neural tissues by measuring the turnover rates of pathway substrates
Methods Enzymol, 451, 639-51
PubMed 19185743 -
SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome
Am J Hum Genet, 82 (4), 1003-10
PubMed 18342287 -
Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis
Mol Biol Cell, 19 (8), 3390-403
PubMed 18480409 -
ADP-ribosylation of actin by the Clostridium botulinum C2 toxin in mammalian cells results in delayed caspase-dependent apoptotic cell death
Infect Immun, 76 (10), 4600-8
PubMed 18710868 -
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Autophagy, 4 (2), 151-75
PubMed 18188003 -
The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
Autophagy, 4 (4), 500-6
PubMed 18326940 -
Mechanisms and functions of endocytosis
J Cell Biol, 180 (1), 7-11
PubMed 18195098 -
Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45
Mol Biol Cell, 19 (10), 4167-76
PubMed 18685079 -
Different modes of programmed cell death during oogenesis of the silkmoth Bombyx mori
Autophagy, 4 (1), 97-100
PubMed 17986869 -
Monitoring autophagy in insect eggs
Methods Enzymol, 451, 669-83
PubMed 19185745 -
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
J Cell Biol, 180 (6), 1065-71
PubMed 18347073 -
Geldanamycin-induced down-regulation of ErbB2 from the plasma membrane is clathrin dependent but proteasomal activity independent
Mol Cancer Res, 6 (3), 491-500
PubMed 18337455 -
Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking
Exp Cell Res, 314 (4), 801-13
PubMed 18031739 -
Membranes and organelles
Curr Opin Cell Biol, 20 (4), 357-9
PubMed 18588977 -
An endosomally localized isoform of Eps15 interacts with Hrs to mediate degradation of epidermal growth factor receptor
J Cell Biol, 180 (6), 1205-18
PubMed 18362181 -
ESCRTing autophagic clearance of aggregating proteins
Autophagy, 4 (2), 233-236 -
ESCRT functions in autophagy and associated disease
Cell Cycle, 7 (9), 1166-72
PubMed 18418046 -
Clathrin-independent endocytosis: from nonexisting to an extreme degree of complexity
Histochem Cell Biol, 129 (3), 267-76
PubMed 18193449 -
Cell biology: Viruses in camouflage
Nature, 453 (7194), 466-7
PubMed 18497813 -
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
Autophagy, 4 (2), 176-84
PubMed 18059160 -
Self-eating from an ER-associated cup
J Cell Biol, 182 (4), 621-2
PubMed 18725534 -
Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus
Mol Cell Biol, 28 (12), 4129-41
PubMed 18411303 -
Cellular trafficking of quantum dot-ligand bioconjugates and their induction of changes in normal routing of unconjugated ligands
Nano Lett, 8 (7), 1858-65
PubMed 18570482 -
Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation
Mol Biol Cell, 19 (8), 3454-62
PubMed 18508924 -
The Mitogen-activated protein kinase p38 links Shiga Toxin-dependent signaling and trafficking
Mol Biol Cell, 19 (1), 95-104
PubMed 17959827 -
FGF-1: from biology through engineering to potential medical applications
Crit Rev Clin Lab Sci, 45 (1), 91-135
PubMed 18293181
Publications 2007
-
The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis
Exp Cell Res, 313 (8), 1696-709
PubMed 17382318 -
Fibroblast growth factor receptor-induced phosphorylation of STAT1 at the Golgi apparatus without translocation to the nucleus
J Cell Physiol, 212 (1), 148-56
PubMed 17311277 -
Endocytosis of the dermatan sulfate proteoglycan decorin utilizes multiple pathways and is modulated by epidermal growth factor receptor signaling
Biochimie, 89 (5), 637-57
PubMed 17335953 -
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
J Cell Biol, 179 (3), 485-500
PubMed 17984323 -
Aberrant receptor signaling and trafficking as mechanisms in oncogenesis
Crit Rev Oncog, 13 (1), 39-74
PubMed 17956217 -
Visualisation of liposomes prepared from skin and stratum corneum lipids by transmission electron microscopy
Micron, 38 (8), 777-81
PubMed 17681473 -
Origin and evolution of self-consumption: autophagy
Adv Exp Med Biol, 607, 111-8
PubMed 17977463 -
Structural requirements for furin-induced cleavage and activation of Shiga toxin
Biochem Biophys Res Commun, 357 (1), 144-9
PubMed 17407762 -
Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells
Eur J Cell Biol, 86 (7), 405-15
PubMed 17601634 -
ESCRTs
Curr Biol, 17 (2), R42-3
PubMed 17240322 -
Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation
Traffic, 8 (11), 1617-29
PubMed 17714434 -
Productive entry of type C foot-and-mouth disease virus into susceptible cultured cells requires clathrin and is dependent on the presence of plasma membrane cholesterol
Virology, 369 (1), 105-18
PubMed 17714753 -
A nuclear export sequence located on a beta-strand in fibroblast growth factor-1
J Biol Chem, 282 (36), 26245-56
PubMed 17616529 -
Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films
J Struct Biol, 158 (3), 386-400
PubMed 17287132 -
Cell death induced by GSM 900-MHz and DCS 1800-MHz mobile telephony radiation
Mutat Res, 626 (1-2), 69-78
PubMed 17045516 -
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
J Biol Chem, 282 (33), 24131-45
PubMed 17580304 -
RILP is required for the proper morphology and function of late endosomes
J Cell Sci, 120 (Pt 21), 3729-37
PubMed 17959629 -
GASA4, one of the 14-member Arabidopsis GASA family of small polypeptides, regulates flowering and seed development
Plant Cell Physiol, 48 (3), 471-83
PubMed 17284469 -
Developmental biology: moonlighting at the pole
Nature, 445 (7127), 497-9
PubMed 17268460 -
ESCRTs and Fab1 regulate distinct steps of autophagy
Curr Biol, 17 (20), 1817-25
PubMed 17935992 -
Linking lysosomal trafficking defects with changes in aging and stress response in Drosophila
Autophagy, 3 (5), 499-501
PubMed 17617737 -
Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles
Genetics, 176 (2), 1283-97
PubMed 17435236 -
Stimulating the cell's appetite for itself
Nat Chem Biol, 3 (6), 304-6
PubMed 17510644 -
Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins
Traffic, 8 (3), 297-309
PubMed 17319803 -
Polyunsaturated fatty acids regulate Shiga toxin transport
Biochem Biophys Res Commun, 364 (2), 283-8
PubMed 17942073 -
Protein kinase Cdelta is activated by Shiga toxin and regulates its transport
J Biol Chem, 282 (22), 16317-28
PubMed 17403690 -
SNX1 and SNX2 mediate retrograde transport of Shiga toxin
Biochem Biophys Res Commun, 358 (2), 566-70
PubMed 17498660 -
Stage-specific regulation of programmed cell death during oogenesis of the medfly Ceratitis capitata (Diptera, Tephritidae)
Int J Dev Biol, 51 (1), 57-66
PubMed 17183465 -
Mechanisms of programmed cell death during oogenesis in Drosophila virilis
Cell Tissue Res, 327 (2), 399-414
PubMed 17004067 -
Apoptosis and autophagy function cooperatively for the efficacious execution of programmed nurse cell death during Drosophila virilis oogenesis
Autophagy, 3 (2), 130-2
PubMed 17183224 -
Indirubin-3'-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK
Oncogene, 26 (44), 6372-85
PubMed 17533378
Publications 2006
-
The function of ubiquitin-binding protein complexes in endocytic downregulation of growth factor receptors
Crit Rev Oncog, 12 (3-4), 301; discussion 301-2
PubMed 17425510 -
The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor
Mol Biol Cell, 17 (6), 2513-23
PubMed 16554368 -
Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1
Gene, 371 (1), 34-41
PubMed 16448788 -
Depletion of sphingolipids facilitates endosome to Golgi transport of ricin
Traffic, 7 (9), 1243-53
PubMed 16919154 -
Working out coupled monoubiquitination
Nat Cell Biol, 8 (11), 1218-9
PubMed 17077855 -
Specification of SUMO1- and SUMO2-interacting motifs
J Biol Chem, 281 (23), 16117-27
PubMed 16524884 -
Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
Nat Struct Mol Biol, 13 (3), 272-7
PubMed 16462748 -
Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain
Nat Struct Mol Biol, 13 (11), 1031-2
PubMed 17057714 -
Regulation of ubiquitin-binding proteins by monoubiquitination
Nat Cell Biol, 8 (2), 163-9
PubMed 16429130 -
Annexin A2 recognises a specific region in the 3'-UTR of its cognate messenger RNA
Biochim Biophys Acta, 1763 (11), 1325-34
PubMed 17045350 -
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
EMBO J, 25 (4), 683-92
PubMed 16467847 -
Transcriptional targeting of small interfering RNAs into cancer cells
Biochem Biophys Res Commun, 350 (4), 854-9
PubMed 17034763 -
Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits
Mol Cell Biol, 26 (2), 389-401
PubMed 16382132 -
EGF-induced activation of the EGF receptor does not trigger mobilization of caveolae
Traffic, 7 (11), 1518-27
PubMed 16984407 -
Reduced binding of FGF1 to mutant fibroblast growth factor receptor 3
Growth Factors, 24 (2), 111-9
PubMed 16801131 -
Shiga toxin regulates its entry in a Syk-dependent manner
Mol Biol Cell, 17 (3), 1096-109
PubMed 16371508 -
Endocytic processing of connexin43 gap junctions: a morphological study
Biochem J, 393 (Pt 1), 59-67
PubMed 16162097 -
A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body
Exp Cell Res, 312 (11), 2018-27
PubMed 16600212 -
How a RING finger protein and a steroid hormone control autophagy
Autophagy, 2 (4), 321-2
PubMed 16874068 -
Regulation of membrane traffic by phosphoinositide 3-kinases
J Cell Sci, 119 (Pt 4), 605-14
PubMed 16467569 -
FGF-1 as a possible carrier for targeted drug delivery
Oncol Res, 16 (1), 27-34
PubMed 16783965 -
A mutant human IgG molecule with only one C1q binding site can activate complement and induce lysis of target cells
Eur J Immunol, 36 (1), 129-38
PubMed 16323243 -
Programmed cell death of the ovarian nurse cells during oogenesis of the silkmoth Bombyx mori
Dev Growth Differ, 48 (7), 419-28
PubMed 16961589 -
Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor
Exp Cell Res, 312 (16), 3036-48
PubMed 16859684 -
Programmed cell death of follicular epithelium during the late developmental stages of oogenesis in the fruit flies Bactrocera oleae and Ceratitis capitata (Diptera, Tephritidae) is mediated by autophagy
Dev Growth Differ, 48 (3), 189-98
PubMed 16573736 -
Follicular atresia during Dacus oleae oogenesis
J Insect Physiol, 52 (3), 282-90
PubMed 16368106 -
Chromatin condensation of ovarian nurse and follicle cells is regulated independently from DNA fragmentation during Drosophila late oogenesis
Differentiation, 74 (6), 293-304
PubMed 16831198 -
Autophagy is required for the degeneration of the ovarian follicular epithelium in higher Diptera
Autophagy, 2 (4), 297-8
PubMed 16921270 -
Hrs makes receptors silent: a key to endosomal protein sorting
Crit Rev Oncog, 12 (3-4), 295, discussion 295-6
PubMed 17425508 -
A new side to ubiquitin
Trends Biochem Sci, 31 (10), 541-4
PubMed 16901703 -
Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains
J Cell Sci, 119 (Pt 12), 2414-24
PubMed 16720641 -
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors
Mol Biol Cell, 17 (9), 3989-4001
PubMed 16837550 -
Analyzing phosphoinositides and their interacting proteins
Nat Methods, 3 (4), 251-8
PubMed 16554828 -
The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport
J Cell Sci, 119 (Pt 19), 3944-57
PubMed 16954148 -
CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4
EMBO J, 25 (16), 3738-49
PubMed 16888620 -
Endosomal and non-endosomal functions of ESCRT proteins
Trends Cell Biol, 16 (6), 317-26
PubMed 16716591 -
EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol
Mol Biol Cell, 17 (4), 1664-75
PubMed 16452630 -
Thymidine secretion by hybridoma and myeloma cells
Biochem Biophys Res Commun, 342 (1), 221-6
PubMed 16472778 -
Functional diversity of FGF-2 isoforms by intracellular sorting
Bioessays, 28 (5), 504-14
PubMed 16615083 -
Different abilities of the four FGFRs to mediate FGF-1 translocation are linked to differences in the receptor C-terminal tail
J Cell Sci, 119 (Pt 20), 4332-41
PubMed 17003104 -
Transport of ricin from endosomes to the Golgi apparatus is regulated by Rab6A and Rab6A'
Traffic, 7 (6), 663-72
PubMed 16683916 -
FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus
J Biol Chem, 281 (16), 11405-12
PubMed 16495214 -
Structural requirements of FGF-1 for receptor binding and translocation into cells
Biochemistry, 45 (51), 15338-48
PubMed 17176056
Publications 2005
-
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
J Cell Biol, 171 (4), 603-14
PubMed 16286508 -
Alix regulates cortical actin and the spatial distribution of endosomes
J Cell Sci, 118 (Pt 12), 2625-35
PubMed 15914539 -
Identification of human and rat FAD-AMP lyase (cyclic FMN forming) as ATP-dependent dihydroxyacetone kinases
Biochem Biophys Res Commun, 338 (4), 1682-9
PubMed 16289032 -
Fluorimetric HPLC detection of endogenous riboflavin 4',5'-cyclic phosphate in rat liver at nanomolar concentrations
Anal Biochem, 341 (2), 214-9
PubMed 15907866 -
Overexpression of proteasome beta5 assembled subunit increases the amount of proteasome and confers ameliorated response to oxidative stress and higher survival rates
J Biol Chem, 280 (12), 11840-50
PubMed 15661736 -
Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism
Traffic, 6 (2), 144-56
PubMed 15634214 -
Cellular internalization of cytolethal distending toxin: a new end to a known pathway
Cell Microbiol, 7 (7), 921-34
PubMed 15953025 -
Ubiquitylation and cell signaling
EMBO J, 24 (19), 3353-9
PubMed 16148945 -
Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation
EMBO Rep, 6 (7), 635-41
PubMed 15962011 -
Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors
J Cell Sci, 118 (Pt 17), 3869-81
PubMed 16091423 -
The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity
J Neurosci, 25 (11), 2793-802
PubMed 15772339 -
Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B
Cell, 121 (3), 437-50
PubMed 15882625 -
Caveolae: stable membrane domains with a potential for internalization
Traffic, 6 (9), 720-4
PubMed 16101676 -
[Ricin--a therapeutic agent and a biological weapon]
Tidsskr Nor Laegeforen, 125 (18), 2477-9
PubMed 16186864 -
The Rab5 effector Rabaptin-5 and its isoform Rabaptin-5delta differ in their ability to interact with the small GTPase Rab4
FEBS J, 272 (1), 37-46
PubMed 15634330 -
Ubiquitinated annexin A2 is enriched in the cytoskeleton fraction
FEBS Lett, 579 (1), 203-6
PubMed 15620714 -
Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2
Int J Cancer, 116 (3), 359-67
PubMed 15800944 -
Morphological irregularities and features of resistance to apoptosis in the dcp-1/pita double mutated egg chambers during Drosophila oogenesis
Cell Motil Cytoskeleton, 60 (1), 14-23
PubMed 15547953 -
Presence of multiple sites containing polar material in spherical Escherichia coli cells that lack MreB
J Bacteriol, 187 (17), 6187-96
PubMed 16109960 -
Delivery into cells: lessons learned from plant and bacterial toxins
Gene Ther, 12 (11), 865-72
PubMed 15815697 -
Strategies for the design of random siRNA libraries and the selection of anti-GFP siRNAs
Methods Mol Biol, 309, 83-91
PubMed 15990399 -
Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain
J Biol Chem, 280 (20), 19600-6
PubMed 15755741 -
Diphtheria toxin translocation across cellular membranes is regulated by sphingolipids
Biochem Biophys Res Commun, 329 (2), 465-73
PubMed 15737610 -
Reconstitution of active diphtheria toxin based on a hexahistidine tagged version of the B-fragment produced to high yields in bacteria
Toxicon, 46 (8), 900-6
PubMed 16260019 -
The A-subunit of surface-bound Shiga toxin stimulates clathrin-dependent uptake of the toxin
FEBS J, 272 (16), 4103-13
PubMed 16098193 -
Actin-based motility of endosomes is linked to the polar tip growth of root hairs
Eur J Cell Biol, 84 (6), 609-21
PubMed 16032929 -
Two nuclear localization signals required for transport from the cytosol to the nucleus of externally added FGF-1 translocated into cells
Biochemistry, 44 (16), 6071-80
PubMed 15835896 -
Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1
Mol Biol Cell, 16 (2), 794-810
PubMed 15574884 -
Highly stable mutants of human fibroblast growth factor-1 exhibit prolonged biological action
J Mol Biol, 352 (4), 860-75
PubMed 16126225
Publications 2004
-
The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation
Mol Biol Cell, 15 (9), 4337-46
PubMed 15240819 -
Defective downregulation of receptor tyrosine kinases in cancer
EMBO J, 23 (14), 2707-12
PubMed 15229652 -
Protein targeting to endosomes and phagosomes via FYVE and PX domains
Curr Top Microbiol Immunol, 282, 89-115
PubMed 14594215 -
[Impaired cerebral autoregulation in asymptomatic patients with carotid artery stenosis: comparison of acetazolamide-SPECT and transcranial CO(2)-dopplersonography]
Zentralbl Chir, 129 (3), 178-82
PubMed 15237321 -
The biogenesis of multivesicular endosomes
Nat Rev Mol Cell Biol, 5 (4), 317-23
PubMed 15071556 -
Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites
J Cell Sci, 117 (Pt 12), 2557-68
PubMed 15128873 -
ERK2 prohibits apoptosis-induced subcellular translocation of orphan nuclear receptor NGFI-B/TR3
J Biol Chem, 279 (48), 50097-101
PubMed 15448159 -
Trafficking and signaling pathways of nuclear localizing protein ligands and their receptors
Bioessays, 26 (9), 993-1004
PubMed 15351969 -
Cloning and characterization of the genes encoding toxic lectins in mistletoe (Viscum album L)
Eur J Biochem, 271 (12), 2350-60
PubMed 15182350 -
Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases
J Biol Chem, 279 (31), 32786-95
PubMed 15159412 -
Efficient endosome-to-Golgi transport of Shiga toxin is dependent on dynamin and clathrin
J Cell Sci, 117 (Pt 11), 2321-31
PubMed 15126632 -
Caveolin-1 and MAL are located on prostasomes secreted by the prostate cancer PC-3 cell line
J Cell Sci, 117 (Pt 22), 5343-51
PubMed 15466889 -
Translocation of FGF-1 and FGF-2 across vesicular membranes occurs during G1-phase by a common mechanism
Mol Biol Cell, 15 (2), 801-14
PubMed 14657241 -
Branching sites and morphological abnormalities behave as ectopic poles in shape-defective Escherichia coli
Mol Microbiol, 52 (4), 1045-54
PubMed 15130123 -
Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner
J Biol Chem, 279 (6), 4794-801
PubMed 14604990 -
The history of ricin, abrin and related toxins
Toxicon, 44 (4), 361-70
PubMed 15302520 -
Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway
Dev Cell, 7 (2), 179-92
PubMed 15296715 -
Pathways followed by protein toxins into cells
Int J Med Microbiol, 293 (7-8), 483-90
PubMed 15149022 -
Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes
J Cell Biol, 164 (6), 923-33
PubMed 15007060 -
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
J Cell Sci, 117 (Pt 18), 4239-51
PubMed 15292400 -
The structure of an endosomal protein sorter
Dev Cell, 7 (4), 457-8
PubMed 15469831 -
Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits
Mol Biol Cell, 15 (8), 3591-604
PubMed 15194809 -
Deletion mutant of FGFR4 induces onion-like membrane structures in the nucleus
J Cell Sci, 117 (Pt 9), 1807-19
PubMed 15075241 -
Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria
Mol Cell Biol, 24 (10), 4593-604
PubMed 15121875 -
Signaling, internalization, and intracellular activity of fibroblast growth factor
Curr Top Microbiol Immunol, 286, 45-79
PubMed 15645710 -
Design of fully active FGF-1 variants with increased stability
Protein Eng Des Sel, 17 (8), 603-11
PubMed 15469994
Publications 2003
-
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes
J Cell Biol, 162 (3), 435-42
PubMed 12900395 -
STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
J Biol Chem, 278 (14), 12513-21
PubMed 12551915 -
Endosome-to-Golgi transport is regulated by protein kinase A type II alpha
J Biol Chem, 278 (3), 1991-7
PubMed 12419802 -
Cytotoxic activity of 6-alkynyl- and 6-alkenylpurines
Bioorg Med Chem Lett, 13 (5), 877-80
PubMed 12617912 -
IL-7 receptor is present on human microvascular endothelial cells
Immunol. Lett., 86 (2), 163-168 -
IL-7 receptor is present on human microvascular endothelial cells
Immunol Lett, 86 (2), 163-8
PubMed 12644318 -
Phosphatidylinositol 3-phosphate is found in microdomains of early endosomes
Histochem Cell Biol, 120 (6), 445-53
PubMed 14618335 -
Endocytosis and signaling: a relationship under development
Cell, 115 (5), 513-21
PubMed 14651844 -
MHC class II loading of high or low affinity peptides directed by Ii/peptide fusion constructs: implications for T cell activation
Int Immunol, 15 (11), 1291-9
PubMed 14565927 -
The cytoplasmic tail of invariant chain modulates antigen processing and presentation
Eur J Immunol, 33 (2), 277-86
PubMed 12548558 -
Distinct monoubiquitin signals in receptor endocytosis
Trends Biochem Sci, 28 (11), 598-603
PubMed 14607090 -
Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation
Nat Cell Biol, 5 (5), 461-6
PubMed 12717448 -
Clathrin-coated pits with long, dynamin-wrapped necks upon expression of a clathrin antisense RNA
Proc Natl Acad Sci U S A, 100 (9), 5175-80
PubMed 12682302 -
Characterization and tissue expression of acidic fibroblast growth factor binding protein homologue in Drosophila melanogaster
Gene, 310, 185-91
PubMed 12801646 -
Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors
J Biol Chem, 278 (41), 39735-46
PubMed 12874286 -
Induction of direct endosome to endoplasmic reticulum transport in Chinese hamster ovary (CHO) cells (LdlF) with a temperature-sensitive defect in epsilon-coatomer protein (epsilon-COP)
J Biol Chem, 278 (37), 35850-5
PubMed 12847103 -
The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
Dev Cell, 5 (5), 709-22
PubMed 14602072 -
Phosphatidylinositol-3 kinase-dependent activation of Akt does not correlate with either high mitogenicity or cell migration induced by FGF-1
Anticancer Res, 23 (5A), 4071-7
PubMed 14666721 -
Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes
Biochem J, 372 (Pt 3), 861-9
PubMed 12646047 -
Modes of programmed cell death during Ceratitis capitata oogenesis
Tissue Cell, 35 (2), 113-9
PubMed 12747933 -
Enterolysin A, a cell wall-degrading bacteriocin from Enterococcus faecalis LMG 2333
Appl Environ Microbiol, 69 (5), 2975-84
PubMed 12732574 -
Transport of exogenous growth factors and cytokines to the cytosol and to the nucleus
Physiol Rev, 83 (1), 163-82
PubMed 12506129 -
PI3P signaling regulates receptor sorting but not transport in the endosomal pathway
J Cell Biol, 162 (6), 971-9
PubMed 12975344 -
Protein sorting into multivesicular endosomes
Curr Opin Cell Biol, 15 (4), 446-55
PubMed 12892785 -
Isolation and characterization of a new d-galactose-binding lectin from Sambucus racemosa L
Protein Pept Lett, 10 (3), 287-93
PubMed 12871149 -
Cholera toxin internalization and intoxication - Reply
J. Cell Sci., 116 (3), 432-433 -
Phosphorylation of insulin-like growth factor binding protein-3 by deoxyribonucleic acid-dependent protein kinase reduces ligand binding and enhances nuclear accumulation
Endocrinology, 144 (5), 1984-93
PubMed 12697706 -
High molecular weight DNA fragments are processed by caspase sensitive or caspase independent pathways in cultures of cerebellar granule neurons
Brain Res, 984 (1-2), 111-21
PubMed 12932845 -
Role of lipids in the retrograde pathway of ricin intoxication
Traffic, 4 (8), 544-552 -
Role of lipids in the retrograde pathway of ricin intoxication
Traffic, 4 (8), 544-52
PubMed 12839497 -
Differential role of actin, clathrin, and dynamin in Fc gamma receptor-mediated endocytosis and phagocytosis
J Biol Chem, 278 (5), 3331-8
PubMed 12424246 -
Caveolae: anchored, multifunctional platforms in the lipid ocean
Trends Cell Biol, 13 (2), 92-100
PubMed 12559760 -
Cholesterol loading induces a block in the exit of VSVG from the TGN
Traffic, 4 (11), 772-84
PubMed 14617359
Publications 2002
-
Cytotoxic and antibacterial activity of 2-oxopurine derivatives
Bioorg Med Chem Lett, 12 (4), 567-9
PubMed 11844673 -
Phosphorylation of Hrs downstream of the epidermal growth factor receptor
Eur J Biochem, 269 (16), 3881-7
PubMed 12180964 -
The carboxyl-terminal domains of IgA and IgM direct isotype-specific polymerization and interaction with the polymeric immunoglobulin receptor
J Biol Chem, 277 (45), 42755-62
PubMed 12213814 -
Membrane ruffling and macropinocytosis in A431 cells require cholesterol
J Cell Sci, 115 (Pt 14), 2953-62
PubMed 12082155 -
Synthesis and antimycobacterial activity of 6-arylpurines: the requirements for the N-9 substituent in active antimycobacterial purines
J Med Chem, 45 (6), 1383-6
PubMed 11882008 -
Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors
Proc Natl Acad Sci U S A, 99 (19), 12191-6
PubMed 12218189 -
The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking
J Cell Sci, 115 (Pt 5), 899-911
PubMed 11870209 -
Uncoating ATPase Hsc70 is recruited by invariant chain and controls the size of endocytic compartments
Proc Natl Acad Sci U S A, 99 (3), 1515-20
PubMed 11818572 -
Selective regulation of the Rab9-independent transport of ricin to the Golgi apparatus by calcium
J Cell Sci, 115 (Pt 17), 3449-56
PubMed 12154075 -
[A short form of the heparin-binding EGF-like growth factor with a changed EGF domain]
Mol Biol (Mosk), 36 (1), 76-83
PubMed 11862716 -
A short form of the heparin-binding EGF-like growth factor with a changed EGF domain
Mol. Biol., 36 (1), 58-64 -
Vesicle transmembrane potential is required for translocation to the cytosol of externally added FGF-1
EMBO J, 21 (17), 4480-90
PubMed 12198150 -
Steroid signal transduction activated at the cell membrane: from plants to animals
Acta Biochim Pol, 49 (3), 735-45
PubMed 12422243 -
Role of Rab5 in the recruitment of hVps34/p150 to the early endosome
Traffic, 3 (6), 416-27
PubMed 12010460 -
Dynamics of apoptosis in the ovarian follicle cells during the late stages of Drosophila oogenesis
Cell Tissue Res, 307 (3), 401-9
PubMed 11904777 -
The cytoplasmic tail of invariant chain regulates endosome fusion and morphology
Mol Biol Cell, 13 (6), 1846-56
PubMed 12058053 -
Early endosomal regulation of Smad-dependent signaling in endothelial cells
J Biol Chem, 277 (20), 18046-52
PubMed 11877415 -
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes
Nat Cell Biol, 4 (5), 394-8
PubMed 11988743 -
Hrs and endocytic sorting of ubiquitinated membrane proteins
Cell Struct Funct, 27 (6), 403-8
PubMed 12576633 -
Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding
J Biol Chem, 277 (21), 18954-60
PubMed 11886870 -
Pathways followed by ricin and Shiga toxin into cells
Histochem Cell Biol, 117 (2), 131-41
PubMed 11935289 -
Membrane traffic exploited by protein toxins
Annu Rev Cell Dev Biol, 18, 1-24
PubMed 12142266 -
Transport of protein toxins into cells: pathways used by ricin, cholera toxin and Shiga toxin
FEBS Lett, 529 (1), 49-53
PubMed 12354612 -
Past-A, a novel proton-associated sugar transporter, regulates glucose homeostasis in the brain
J Neurosci, 22 (21), 9160-5
PubMed 12417639 -
Binding of FGF-1 variants to protein kinase CK2 correlates with mitogenicity
EMBO J, 21 (15), 4058-69
PubMed 12145206 -
Identification of ribosome-binding protein p34 as an intracellular protein that binds acidic fibroblast growth factor
J Biol Chem, 277 (26), 23864-71
PubMed 11964394 -
Nuclear receptor and apoptosis initiator NGFI-B is a substrate for kinase ERK2
Biochem Biophys Res Commun, 291 (5), 1146-50
PubMed 11883936 -
The phosphatidylinositol 3-phosphate-binding FYVE finger
FEBS Lett, 513 (1), 77-84
PubMed 11911884 -
Expression of human protein tyrosine phosphatase epsilon in leucocytes: a potential ERK pathway-regulating phosphatase
Scand J Immunol, 56 (2), 195-203
PubMed 12121439 -
Retrograde transport of ricin
Int J Med Microbiol, 291 (6-7), 517-21
PubMed 11890552
Publications 2001
-
Modulation of intracellular transport of acidic fibroblast growth factor by mutations in the cytoplasmic receptor domain
J Cell Sci, 114 (Pt 9), 1677-89
PubMed 11398757 -
An interaction between ricin and calreticulin that may have implications for toxin trafficking
J Biol Chem, 276 (10), 7202-8
PubMed 11113144 -
Ability of the Tat basic domain and VP22 to mediate cell binding, but not membrane translocation of the diphtheria toxin A-fragment
Biochemistry, 40 (14), 4349-58
PubMed 11284691 -
Ability of the Tat basic domain and VP22 to mediate cell binding, but not membrane translocation of the diphtheria toxin A-fragment
Biochemistry, 40 (14), 4349-4358 -
Reconstitution of clathrin-independent endocytosis at the apical domain of permeabilized MDCK II cells: requirement for a Rho-family GTPase
Traffic, 2 (1), 26-36
PubMed 11208166 -
Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins
Biochem J, 355 (Pt 2), 249-58
PubMed 11284710 -
Phosphoinositides and phagocytosis
J Cell Biol, 155 (1), 15-7
PubMed 11581282 -
Cell biology. A lipid oils the endocytosis machine
Science, 291 (5506), 993-4
PubMed 11232585 -
Endosome to Golgi transport of ricin is independent of clathrin and of the Rab9- and Rab11-GTPases
Mol Biol Cell, 12 (7), 2099-107
PubMed 11452006 -
Trafficking of phosphatidylinositol 3-phosphate from the trans-Golgi network to the lumen of the central vacuole in plant cells
Plant Cell, 13 (2), 287-301
PubMed 11226186 -
Fluid phase endocytosis of [125I]iodixanol in rat liver parenchymal, endothelial and Kupffer cells
Cell Tissue Res, 304 (2), 221-30
PubMed 11396716 -
Wortmannin-sensitive trafficking steps in the endocytic pathway in rat liver endothelial cells
Biochem J, 357 (Pt 2), 497-503
PubMed 11439100 -
Proteoglycan synthesis is increased in cells with impaired clathrin-dependent endocytosis
J Cell Sci, 114 (Pt 2), 335-43
PubMed 11148135 -
Two farms of the heparin-binding EGF-like growth factor precursor, a receptor for diphtheria toxin
Mol. Biol., 35 (1), 122-129 -
[Two forms of precursors of a heparin-binding EGF-like growth factor-diphtheria toxin receptor]
Mol Biol (Mosk), 35 (1), 136-45
PubMed 11234372 -
'Troy-bodies': antibodies as vector proteins for T cell epitopes
Biomol Eng, 18 (3), 109-16
PubMed 11566602 -
Evading apoptosis by calcitriol-differentiated human leukemic HL-60 cells is not mediated by changes in CD95 receptor system but by increased sensitivity of these cells to insulin
Exp Cell Res, 270 (1), 119-27
PubMed 11597134 -
Effects of inhibitors of the vacuolar proton pump on hepatic heterophagy and autophagy
Biochim Biophys Acta, 1510 (1-2), 243-57
PubMed 11342162 -
Actin cytoskeleton reorganization of the apoptotic nurse cells during the late developmental stages of oogenesis in Dacus oleae
Cell Motil Cytoskeleton, 48 (3), 224-33
PubMed 11223953 -
Ricin
Toxicon, 39 (11), 1723-8
PubMed 11595634 -
Microbiology. Fighting anthrax with a mutant toxin
Science, 292 (5517), 647-8
PubMed 11330322 -
A PtdIns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells
Curr Biol, 11 (20), 1636-42
PubMed 11676927 -
Hrs recruits clathrin to early endosomes
EMBO J, 20 (17), 5008-21
PubMed 11532964 -
Function of Hrs in endocytic trafficking and signalling
Biochem Soc Trans, 29 (Pt 4), 472-5
PubMed 11498011 -
FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes
J Cell Sci, 114 (Pt 12), 2255-63
PubMed 11493665 -
Shiga toxins
Toxicon, 39 (11), 1629-35
PubMed 11595626 -
In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy
Int J Cancer, 92 (5), 761-6
PubMed 11340584 -
PX domains: attracted by phosphoinositides
Nat Cell Biol, 3 (8), E179-82
PubMed 11483972 -
The role of phosphoinositides in membrane transport
Curr Opin Cell Biol, 13 (4), 485-92
PubMed 11454456 -
DNA binding-independent transcriptional activation by the androgen receptor through triggering of coactivators
J Biol Chem, 276 (33), 31030-6
PubMed 11429409 -
Introduction. Trafficking of lipids
Semin Cell Dev Biol, 12 (2), 135-7
PubMed 11292379 -
Intracellular trafficking and turnover of phosphatidylinositol 3-phosphate
Semin Cell Dev Biol, 12 (2), 193-9
PubMed 11292385 -
The Rab GTPase family
Genome Biol, 2 (5), REVIEWS3007
PubMed 11387043 -
The Rab GTPase family
Genome Biol., 2 (5), 3007.1 -
Internalization of cholera toxin by different endocytic mechanisms
J Cell Sci, 114 (Pt 20), 3737-47
PubMed 11707525
Publications 2000
-
Regulation and intracellular trafficking pathways of the endothelin receptors
J Biol Chem, 275 (23), 17596-604
PubMed 10747877 -
Reduced [3H]IP3 binding but unchanged IP3 receptor levels in the rat hippocampus CA1 region following transient global ischemia and tolerance induction
Neurochem Int, 36 (4-5), 379-88
PubMed 10733005 -
Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages
J Cell Sci, 113 Pt 19, 3531-41
PubMed 10984443 -
Recombinant antibodies as carrier proteins for sub-unit vaccines: influence of mode of fusion on protein production and T-cell activation
J Immunol Methods, 245 (1-2), 119-31
PubMed 11042289 -
Initial events in infectious salmon anemia virus infection: evidence for the requirement of a low-pH step
J Virol, 74 (1), 218-27
PubMed 10590109 -
Design of toxins that can be activated by cell-specific proteases and their potential use in targeted cell killing
Int J Med Microbiol, 290 (4-5), 471-6
PubMed 11111928 -
Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin
J Biol Chem, 275 (6), 4363-8
PubMed 10660606 -
Penetration of protein toxins into cells
Curr Opin Cell Biol, 12 (4), 407-13
PubMed 10873820 -
Ultrastructural characterization of the delimiting membranes of isolated autophagosomes and amphisomes by freeze-fracture electron microscopy
Eur J Cell Biol, 79 (12), 871-82
PubMed 11152279 -
Autophagosome-associated variant isoforms of cytosolic enzymes
Biochem J, 352 Pt 3, 773-81
PubMed 11104685 -
Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues
J Biol Chem, 275 (32), 24595-600
PubMed 10807926 -
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
EMBO J, 19 (17), 4577-88
PubMed 10970851 -
Endosome to Golgi transport of ricin is regulated by cholesterol
Mol Biol Cell, 11 (12), 4205-16
PubMed 11102518 -
Requirement for C-terminal end of fibroblast growth factor receptor 4 in translocation of acidic fibroblast growth factor to cytosol and nucleus
J Cell Sci, 113 ( Pt 10), 1827-38
PubMed 10769213 -
Requirement of phosphatidylinositol 3-kinase activity for translocation of exogenous aFGF to the cytosol and nucleus
J Biol Chem, 275 (16), 11972-80
PubMed 10766827 -
Organization, chromosomal localization and promoter analysis of the gene encoding human acidic fibroblast growth factor intracellular binding protein
Biochem J, 352 Pt 3, 629-35
PubMed 11104667 -
Apical endocytosis of ricin in MDCK cells is regulated by the cyclooxygenase pathway
J Cell Sci, 113 ( Pt 7), 1213-21
PubMed 10704372 -
Fc receptor mediated endocytosis of small soluble immunoglobulin G immune complexes in Kupffer and endothelial cells from rat liver
J Cell Sci, 113 ( Pt 18), 3255-66
PubMed 10954423 -
Stage-specific apoptotic patterns during Drosophila oogenesis
Eur J Cell Biol, 79 (9), 610-20
PubMed 11043402 -
Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor
Mol Biol Cell, 11 (2), 481-95
PubMed 10679008 -
Probing pores with peptide plugs. Topology of membrane-inserted diphtheria toxin
J Gen Physiol, 115 (4), 417-20
PubMed 10736309 -
Commentary - Probing pores with peptide plugs: Topology of membrane-inserted diphtheria toxin
J. Gen. Physiol., 115 (4), 417-420 -
Oral presentations in science and medicine. An art in decline?
Anticancer Res, 20 (5A), 2795-9
PubMed 11062686 -
Ricin transport into cells: studies of endocytosis and intracellular transport
Int J Med Microbiol, 290 (4-5), 415-20
PubMed 11111920 -
Apical macropinocytosis in polarized MDCK cells: regulation by N-ethylmaleimide-sensitive proteins
Eur J Cell Biol, 79 (7), 447-57
PubMed 10961444 -
Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives
EMBO J, 19 (22), 5943-50
PubMed 11080141 -
Release of gelonin from endosomes and lysosomes to cytosol by photochemical internalization
Biochim Biophys Acta, 1475 (3), 307-13
PubMed 10913830 -
Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin
Int J Cancer, 87 (6), 853-9
PubMed 10956397 -
Detection of high molecular weight DNA fragments characteristic of early stage apoptosis in cerebellar granule cells exposed to glutamate
Exp Brain Res, 135 (2), 173-8
PubMed 11131501 -
Mutational analysis of the androgen receptor AF-2 (activation function 2) core domain reveals functional and mechanistic differences of conserved residues compared with other nuclear receptors
Mol Endocrinol, 14 (10), 1603-17
PubMed 11043576 -
Secretion of thymidine by hybridoma cells
Adv Exp Med Biol, 486, 295-301
PubMed 11783504 -
Caveolae: uniform structures with multiple functions in signaling, cell growth, and cancer
Exp Cell Res, 261 (1), 111-8
PubMed 11082281 -
Cycling lipids
Curr Biol, 10 (2), R57-9
PubMed 10662657 -
Membrane traffic: Cycling lipids
Curr. Biol., 10 (2), R57-R59 -
Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate
Mol Cell Biol, 20 (20), 7685-92
PubMed 11003664 -
Externally added aFGF mutants do not require extensive unfolding for transport to the cytosol and the nucleus in NIH/3T3 cells
Biochemistry, 39 (49), 15091-100
PubMed 11106487
Publications 1999
-
Photochemical internalization: a novel technology for delivery of macromolecules into cytosol
Cancer Res, 59 (6), 1180-3
PubMed 10096543 -
Direct interaction of EEA1 with Rab5b
Eur J Biochem, 265 (1), 361-6
PubMed 10491193 -
The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer
Biochem J, 338 ( Pt 2), 539-43
PubMed 10024533 -
Uptake and intracellular transport of acidic fibroblast growth factor: evidence for free and cytoskeleton-anchored fibroblast growth factor receptors
Mol Biol Cell, 10 (11), 3835-48
PubMed 10564275 -
Phosphoinositides in membrane traffic
Curr Opin Cell Biol, 11 (4), 460-5
PubMed 10449332 -
Toxins that are activated by HIV type-1 protease through removal of a signal for degradation by the N-end-rule pathway
Biochem J, 343 Pt 1, 199-207
PubMed 10493930 -
Regulation of endocytic membrane traffic by phosphatidylinositol 3-phosphate
Biochem Soc Trans, 27 (4), 666-70
PubMed 10917663 -
FYVE finger proteins as effectors of phosphatidylinositol 3-phosphate
Chem Phys Lipids, 98 (1-2), 87-94
PubMed 10358931 -
Hepatocyte growth factor (HGF) induces interleukin-11 secretion from osteoblasts: a possible role for HGF in myeloma-associated osteolytic bone disease
Blood, 94 (11), 3883-8
PubMed 10572104 -
Effects of mutations of a phosphorylation site in an exposed loop in acidic fibroblast growth factor
J Biol Chem, 274 (25), 18081-6
PubMed 10364261 -
[The Nobel Prize in physiology and medicine]
Tidsskr Nor Laegeforen, 119 (30), 4450
PubMed 10827478 -
Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
Mol Biol Cell, 10 (4), 961-74
PubMed 10198050 -
Endocytosis and intracellular transport of ricin: recent discoveries
FEBS Lett, 452 (1-2), 67-70
PubMed 10376680 -
The Rab5 effector EEA1 interacts directly with syntaxin-6
J Biol Chem, 274 (41), 28857-60
PubMed 10506127 -
Polarized transport of MHC class II molecules in Madin-Darby canine kidney cells is directed by a leucine-based signal in the cytoplasmic tail of the beta-chain
J Immunol, 163 (5), 2540-8
PubMed 10452991 -
Endocytic mechanisms responsible for uptake of GPI-linked diphtheria toxin receptor
J Cell Sci, 112 ( Pt 22), 3899-909
PubMed 10547351 -
FYVE-finger proteins--effectors of an inositol lipid
J Cell Sci, 112 ( Pt 23), 4175-83
PubMed 10564636 -
Fluid phase endocytosis and galactosyl receptor-mediated endocytosis employ different early endosomes
Biochim Biophys Acta, 1421 (2), 317-28
PubMed 10518701 -
Urokinase-type plasminogen activator receptor is internalized by different mechanisms in polarized and nonpolarized Madin-Darby canine kidney epithelial cells
Mol Biol Cell, 10 (1), 179-95
PubMed 9880335 -
Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol
J Biol Chem, 274 (48), 34443-9
PubMed 10567425 -
[Activation of the cell proliferation program by acidic fibroblast growth factor (aFGF)]
Postepy Hig Med Dosw, 53 (2), 277-89
PubMed 10355293 -
Following angiogenin during angiogenesis: a journey from the cell surface to the nucleolus
Arch Immunol Ther Exp (Warsz), 47 (5), 299-305
PubMed 10604235 -
CD4 cytotoxic and dendritic cells in the immunopathologic lesion of Sjögren's syndrome
Clin Exp Immunol, 118 (1), 154-63
PubMed 10540173
Publications 1998
-
Endocytosed ricin and asialoorosomucoid follow different intracellular pathways in hepatocytes
Biochim Biophys Acta, 1373 (1), 195-208
PubMed 9733965 -
Phacoemulsification in eyes with pseudoexfoliation
J Cataract Refract Surg, 24 (6), 787-92
PubMed 9642589 -
Modulation of the intracellular stability and toxicity of diphtheria toxin through degradation by the N-end rule pathway
EMBO J, 17 (2), 615-25
PubMed 9430652 -
CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1
J Biol Chem, 273 (48), 31853-9
PubMed 9822653 -
FYVE fingers bind PtdIns(3)P
Nature, 394 (6692), 432-3
PubMed 9697764 -
Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion
EMBO J, 17 (7), 1930-40
PubMed 9524116 -
Inability of the acidic fibroblast growth factor mutant K132E to stimulate DNA synthesis after translocation into cells
J Biol Chem, 273 (18), 11164-72
PubMed 9556604 -
Cloning of an intracellular protein that binds selectively to mitogenic acidic fibroblast growth factor
Biochem J, 336 ( Pt 1), 213-22
PubMed 9806903 -
Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus
J Cell Biol, 140 (3), 553-63
PubMed 9456316 -
Transport of apically but not basolaterally internalized ricin to the Golgi apparatus is stimulated by 8-Br-cAMP in MDCK cells
FEBS Lett, 431 (2), 200-4
PubMed 9708902 -
Variation in the proregion structure of heparin-binding EGF-like growth factor precursors
Gene, 212 (1), 1-4
PubMed 9661657 -
Evidence that phosphatidylinositol 3-kinase and p70S6K protein are involved in differentiation of HL-60 cells induced by calcitriol
Anticancer Res, 18 (5A), 3507-14
PubMed 9858932 -
Shiga and Shiga-like toxins
RECENT ADVANCES IN THE PATHOGENESIS OF GASTROINTESTINAL BACTERIAL INFECTIONS, 143-153 -
The leucine-based motif DDQxxLI is recognized both for internalization and basolateral sorting of invariant chain in MDCK cells
Eur J Cell Biol, 76 (1), 25-32
PubMed 9650780 -
Syntaxin-16, a putative Golgi t-SNARE
Eur J Cell Biol, 75 (3), 223-31
PubMed 9587053 -
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
Nature, 394 (6692), 494-8
PubMed 9697774 -
Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5
EMBO J, 17 (7), 1941-51
PubMed 9524117 -
Expression of caveolin-1 and polarized formation of invaginated caveolae in Caco-2 and MDCK II cells
J Cell Sci, 111 ( Pt 6), 825-32
PubMed 9472010 -
Autoantibodies to a novel early endosome antigen 1
Clin Immunol Immunopathol, 86 (1), 81-7
PubMed 9434799 -
Characterization of membrane translocation by anthrax protective antigen
Biochemistry, 37 (45), 15737-46
PubMed 9843379 -
Novel protein toxin-based strategy for development of cytotoxic T lymphocyte vaccines
Arch Immunol Ther Exp (Warsz), 46 (6), 341-6
PubMed 9883312 -
Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells
J Cell Biol, 140 (5), 1039-53
PubMed 9490718 -
Modulation by interleukin-2 of cellular response to fibroblast growth factor-1 in F69-3 fibrosarcoma cells
Exp Cell Res, 244 (1), 61-70
PubMed 9770349
Publications 1997
-
Microtubules are involved in bafilomycin A1-induced tubulation and Rab5-dependent vacuolation of early endosomes
Eur J Cell Biol, 72 (2), 95-103
PubMed 9157016 -
Role of the disulfide bond in Shiga toxin A-chain for toxin entry into cells
J Biol Chem, 272 (17), 11414-9
PubMed 9111051 -
A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function
Cell, 90 (6), 1149-59
PubMed 9323142 -
Structure-function relationship of the ion channel formed by diphtheria toxin in Vero cell membranes
J Membr Biol, 156 (2), 141-8
PubMed 9075645 -
Membrane translocation of diphtheria toxin fragment A exploits early to late endosome trafficking machinery
Mol Microbiol, 23 (3), 445-57
PubMed 9044279 -
Expression of mRNA for a short form of heparin-binding EGF-like growth factor
Gene, 195 (1), 81-6
PubMed 9300824 -
1,25-Dihydroxyvitamin D3 induced activation and subsequent nuclear translocation of MAPK is upstream regulated by PKC in HL-60 cells
Biochem Biophys Res Commun, 241 (2), 419-26
PubMed 9425286 -
Effect of mutation of cytoplasmic receptor domain and of genistein on transport of acidic fibroblast growth factor into cells
Oncogene, 15 (5), 525-36
PubMed 9247306 -
Role of Rab GTPases in membrane traffic
Int Rev Cytol, 176, 1-85
PubMed 9394917 -
[Self-inhibiting N-glycosidase activity of shigella toxin]
Mol Biol (Mosk), 31 (3), 528-35
PubMed 9297098 -
Self-inhibition of N-glycosidase activity of shiga toxin
Mol. Biol., 31 (3), 441-447 -
Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol
Proc Natl Acad Sci U S A, 94 (8), 3783-8
PubMed 9108055 -
Intracellular transport and processing of protein toxins produced by enteric bacteria
Adv Exp Med Biol, 412, 225-32
PubMed 9192018 -
Diphtheria toxin as a molecular tool in the study of acidic fibroblast growth factor signalling
Arch Immunol Ther Exp (Warsz), 45 (5-6), 391-409
PubMed 9437495
Publications 1996
-
Comparison of a diffractive bifocal and a monofocal intraocular lens
J Cataract Refract Surg, 22 (4), 446-51
PubMed 8733848 -
Clathrin-dependent and clathrin-independent endocytosis in liver cells
Z Gastroenterol, 34 Suppl 3, 92-4
PubMed 8767476 -
Density shift of endocytic vesicles induced by uptake of colloidal gold particles in rat hepatocytes
Z Gastroenterol, 34 Suppl 3, 79-80
PubMed 8767471 -
Ability of methotrexate to inhibit translocation to the cytosol of dihydrofolate reductase fused to diphtheria toxin
Biochem J, 313 ( Pt 2), 647-53
PubMed 8573105 -
GPI-anchored diphtheria toxin receptor allows membrane translocation of the toxin without detectable ion channel activity
EMBO J, 15 (4), 725-34
PubMed 8631294 -
Effect of calmodulin antagonists on endocytosis and intracellular transport of ricin in polarized MDCK cells
Exp Cell Res, 227 (2), 298-308
PubMed 8831568 -
Thapsigargin-induced transport of cholera toxin to the endoplasmic reticulum
Proc Natl Acad Sci U S A, 93 (22), 12339-43
PubMed 8901582 -
Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells
Mol Biol Cell, 7 (9), 1391-404
PubMed 8885234 -
Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin
Physiol Rev, 76 (4), 949-66
PubMed 8874490 -
Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger
J Biol Chem, 271 (39), 24048-54
PubMed 8798641 -
Isolation and characterization of early endosomes, late endosomes and terminal lysosomes: their role in protein degradation
J Cell Sci, 109 ( Pt 12), 2905-14
PubMed 9013338 -
Inhibition of the vacuolar H(+)-ATPase with bafilomycin reduces delivery of internalized molecules from mature multivesicular endosomes to lysosomes in HEp-2 cells
Eur J Cell Biol, 69 (4), 343-50
PubMed 8741216 -
Destabilization of plasma membrane structure by prevention of actin polymerization. Microtubule-dependent tubulation of the plasma membrane
J Cell Sci, 109 ( Pt 7), 1655-65
PubMed 8832388 -
[The Anders Jahre medical awarad 1996]
Tidsskr Nor Laegeforen, 116 (23), 2804-6
PubMed 8928170 -
Retrograde transport of acidic fibroblast growth factor as a part of the growth factor signaling
Arch Immunol Ther Exp (Warsz), 44 (4), 201-7
PubMed 9017159 -
Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization
Mol Cell Biol, 16 (1), 270-80
PubMed 8524304
Publications 1995
-
CELL PENETRATION OF BACTERIAL PROTEIN TOXINS - RESPONSE
Trends Microbiol., 3 (5), 167-168 -
Cell-mediated reduction and incomplete membrane translocation of diphtheria toxin mutants with internal disulfides in the A fragment
J Biol Chem, 270 (35), 20787-93
PubMed 7657662 -
Farnesylation of CaaX-tagged diphtheria toxin A-fragment as a measure of transfer to the cytosol
Biochemistry, 34 (35), 11152-9
PubMed 7669773 -
Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants
Exp Cell Res, 218 (1), 39-49
PubMed 7737376 -
Furin-induced cleavage and activation of Shiga toxin
J Biol Chem, 270 (18), 10817-21
PubMed 7738018 -
Inhibition of asialoglycoprotein endocytosis and degradation in rat hepatocytes by protein phosphatase inhibitors
Biochem J, 311 ( Pt 1), 317-26
PubMed 7575471 -
Phorbol myristate acetate selectively stimulates apical endocytosis via protein kinase C in polarized MDCK cells
Exp Cell Res, 217 (1), 157-68
PubMed 7867714 -
Involvement of early and late lysosomes in the degradation of mannosylated ligands by rat liver endothelial cells
Exp Cell Res, 216 (2), 290-8
PubMed 7843273 -
Diphtheria toxin endocytosis and membrane translocation are dependent on the intact membrane-anchored receptor (HB-EGF precursor): studies on the cell-associated receptor cleaved by a metalloprotease in phorbol-ester-treated cells
Biochem J, 310 ( Pt 1), 285-9
PubMed 7646457 -
EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif
J Biol Chem, 270 (22), 13503-11
PubMed 7768953 -
Yeast Ypt51p and mammalian Rab5: counterparts with similar function in the early endocytic pathway
J Cell Sci, 108 ( Pt 11), 3509-21
PubMed 8586662 -
Expression of Rab GTPases using recombinant vaccinia viruses
Methods Enzymol, 257, 155-64
PubMed 8583918 -
Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion
Cell, 83 (3), 423-32
PubMed 8521472 -
Induction of toxin sensitivity in insect cells by infection with baculovirus encoding diphtheria toxin receptor
J Biol Chem, 270 (28), 16879-85
PubMed 7622504 -
Delivery to lysosomes in the human carcinoma cell line HEp-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes
Eur J Cell Biol, 66 (4), 309-23
PubMed 7544728 -
The GDP/GTP cycle of Rab5 in the regulation of endocytotic membrane traffic
Cold Spring Harb Symp Quant Biol, 60, 211-20
PubMed 8824393 -
Translocation of cytosol of exogenous, CAAX-tagged acidic fibroblast growth factor
J Biol Chem, 270 (51), 30680-5
PubMed 8530506 -
Growth inhibition of rat glioma cells in vitro and in vivo by aspirin
J Neurooncol, 24 (2), 171-80
PubMed 7562004
Publications 1994
-
The involvement of the small GTP-binding protein Rab5a in neuronal endocytosis
Neuron, 13 (1), 11-22
PubMed 8043272 -
Selective regulation of apical endocytosis in polarized Madin-Darby canine kidney cells by mastoparan and cAMP
J Biol Chem, 269 (28), 18607-15
PubMed 8034609 -
Diphtheria toxin at low pH depolarizes the membrane, increases the membrane conductance and induces a new type of ion channel in Vero cells
EMBO J, 13 (19), 4433-9
PubMed 7523112 -
Inhibition of membrane translocation of diphtheria toxin A-fragment by internal disulfide bridges
J Biol Chem, 269 (11), 8402-7
PubMed 8132565 -
Entry and uncoating of enveloped viruses
Biochem J, 302 ( Pt 2), 313-20
PubMed 8092981 -
Intermediates in translocation of diphtheria toxin across the plasma membrane
J Biol Chem, 269 (6), 4648-52
PubMed 7508447 -
ENTRY OF SHIGA TOXIN INTO CELLS
INT CONGR SER, 1072, 139-146 -
Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP
J Cell Biol, 126 (1), 53-64
PubMed 8027186 -
Endocytosis and intracellular sorting of ricin and Shiga toxin
FEBS Lett, 346 (1), 99-102
PubMed 8206167 -
Endocytosis without clathrin
Trends Cell Biol, 4 (8), 275-7
PubMed 14731589 -
ENTRY OF SHIGA TOXIN INTO CELLS
ZBL BAKT S, 24, 365-374 -
Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast
J Cell Biol, 125 (2), 283-98
PubMed 8163546 -
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis
EMBO J, 13 (6), 1287-96
PubMed 8137813 -
Distinct structural elements of rab5 define its functional specificity
EMBO J, 13 (3), 575-83
PubMed 8313902 -
Dual mode of signal transduction by externally added acidic fibroblast growth factor
Cell, 76 (6), 1039-51
PubMed 7511061
Publications 1993
-
Membrane translocation of diphtheria toxin A-fragment: role of carboxy-terminal region
Biochemistry, 32 (1), 83-90
PubMed 8418864 -
A chimeric toxin to study the role of the 21 kDa GTP binding protein rho in the control of actin microfilament assembly
EMBO J, 12 (3), 921-31
PubMed 8458345 -
Receptor-mediated endocytosis of ricin in rat liver endothelial cells. An immunocytochemical study
Eur J Cell Biol, 60 (1), 154-62
PubMed 8462592 -
Subcloning and characterization of the binding domain of fragment B of diphtheria toxin
Biochem J, 294 ( Pt 3), 663-6
PubMed 8379922 -
Clathrin and HA2 adaptors: effects of potassium depletion, hypertonic medium, and cytosol acidification
J Cell Biol, 121 (1), 61-72
PubMed 8458873 -
Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors
J Cell Biol, 123 (1), 89-97
PubMed 8408209 -
Endocytosis of desmosomal plaques depends on intact actin filaments and leads to a nondegradative compartment
Eur J Cell Biol, 62 (2), 362-71
PubMed 7925492 -
New cloning opportunities with the use of noncomplementary SfiI adaptors
Biotechniques, 15 (6), 980-2
PubMed 8292350 -
Rapid increase in pH set-point of the Na(+)-in-dependent chloride/bicarbonate antiporter in Vero cells exposed to heat shock
J Membr Biol, 134 (2), 143-53
PubMed 8411117 -
Entry of protein toxins in polarized epithelial cells
Cancer Res, 53 (8), 1755-60
PubMed 8467493 -
Rapid cellular removal of a membrane-inserted foreign polypeptide
Biochem J, 291 ( Pt 2), 473-7
PubMed 8484728 -
Protein toxins acting on intracellular targets: cellular uptake and translocation to the cytosol
Med Microbiol Immunol, 182 (2), 51-61
PubMed 8392658 -
Amplification of c-erbB-2, int-2 and c-myc genes in node-negative breast carcinomas. Relationship to prognosis
Acta Oncol, 32 (3), 289-94
PubMed 8100712 -
Entry of Shiga toxin into cells
Zentralbl Bakteriol, 278 (2-3), 296-305
PubMed 8347933 -
Endocytosis and intracellular transport of protein toxins
Biochem Soc Trans, 21 ( Pt 3) (3), 707-11
PubMed 8224494 -
Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins
J Biol Chem, 268 (24), 18143-50
PubMed 8349690 -
Multivesicular bodies in HEp-2 cells are maturing endosomes
Eur J Cell Biol, 61 (2), 208-24
PubMed 8223712 -
Are caveolae involved in clathrin-independent endocytosis?
Trends Cell Biol, 3 (8), 249-51
PubMed 14731741 -
Rab GTPases in vesicular transport
Curr Opin Cell Biol, 5 (4), 613-20
PubMed 8257602
Publications 1992
-
Replacement of negative by positive charges in the presumed membrane-inserted part of diphtheria toxin B fragment. Effect on membrane translocation and on formation of cation channels
J Biol Chem, 267 (17), 12284-90
PubMed 1376320 -
Internalization efficiency of the transferrin receptor
Exp Cell Res, 199 (1), 19-28
PubMed 1735458 -
Comparative studies on internalization of gold labelled mistletoe lectin I (MLI), its subunits, and of an immunotoxin into mouse L 1210V leukemia cells
Acta Histochem, 92 (1), 46-53
PubMed 1580141 -
Membrane translocation of diphtheria toxin carrying passenger protein domains
Infect Immun, 60 (8), 3296-302
PubMed 1639497 -
Entry of ADP-ribosylating toxins into cells
Curr Top Microbiol Immunol, 175, 1-26
PubMed 1378368 -
Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis
Curr Top Microbiol Immunol, 180, 65-94
PubMed 1324134 -
Genetically engineered toxins in perspective
Targeted Diagn Ther, 7, 465-77
PubMed 1633307 -
The activity of two immunotoxins composed of monoclonal antibody MoAb-16 and A-chain of ricin (MoAb-16-RTA) or A-chain of mistletoe lectin I (MoAb-16-MLIA)
Arch Immunol Ther Exp (Warsz), 40 (3-4), 223-7
PubMed 1300987 -
Effects of brefeldin A on endocytosis, transcytosis and transport to the Golgi complex in polarized MDCK cells
J Cell Biol, 119 (2), 259-72
PubMed 1400572 -
Protein toxins: mode of action and cell entry
Biochem Soc Trans, 20 (4), 724-7
PubMed 1487049 -
Retrograde transport of endocytosed Shiga toxin to the endoplasmic reticulum
Nature, 358 (6386), 510-2
PubMed 1641040 -
Toxin-induced cell lysis: protection by 3-methyladenine and cycloheximide
Exp Cell Res, 200 (2), 253-62
PubMed 1572394 -
Association between diphtheria toxin A- and B-fragment and their fusion proteins
Biochem J, 281 ( Pt 3), 619-25
PubMed 1536643 -
Interactions of diphtheria toxin B-fragment with cells. Role of amino- and carboxyl-terminal regions
J Biol Chem, 267 (13), 8957-62
PubMed 1374382 -
Tight folding of acidic fibroblast growth factor prevents its translocation to the cytosol with diphtheria toxin as vector
EMBO J, 11 (13), 4835-42
PubMed 1281450
Publications 1991
-
Independent regulation of 55-kDa and 75-kDa tumor necrosis factor receptors during activation of human peripheral blood B lymphocytes
Eur J Immunol, 21 (4), 1033-7
PubMed 1850359 -
The preendosomal compartment comprises distinct coated and noncoated endocytic vesicle populations
J Cell Biol, 113 (4), 731-41
PubMed 1673969 -
Colony formation in urinary bladder carcinoma. Relationship to DNA flow cytometry, stage and histopathology
Anticancer Res, 11 (2), 777-81
PubMed 2064333 -
Different metastasis patterns of a human melanoma cell line in nude mice and rats: influence of microenvironment
J Natl Cancer Inst, 83 (14), 1020-4
PubMed 2072409 -
Evidence for involvement of protein kinase C in regulation of intracellular pH by Cl-/HCO-3 antiport
J Membr Biol, 119 (2), 179-86
PubMed 2046087 -
Entry of diphtheria toxin-protein A chimeras into cells
J Biol Chem, 266 (26), 17446-53
PubMed 1894632 -
Effect of monensin on ricin and fluid phase transport in polarized MDCK cells
J Cell Biochem, 47 (3), 251-60
PubMed 1791187 -
Insertion of diphtheria toxin B-fragment into the plasma membrane at low pH. Characterization and topology of inserted regions
J Biol Chem, 266 (4), 2652-9
PubMed 1990012 -
C-erbB-2 protein and neuroendocrine expression in breast carcinomas
Anticancer Res, 11 (1), 161-7
PubMed 1673329 -
Bacterial protein toxins acting on intracellular targets
Semin Cell Biol, 2 (1), 7-14
PubMed 1954345 -
Ricin transport in brefeldin A-treated cells: correlation between Golgi structure and toxic effect
J Cell Biol, 115 (4), 971-81
PubMed 1955466 -
Endocytosis and intracellular transport of the glycolipid-binding ligand Shiga toxin in polarized MDCK cells
J Cell Biol, 113 (3), 553-62
PubMed 1901867 -
Endocytosis without clathrin (a minireview)
Cell Biol Int Rep, 15 (1), 3-8
PubMed 1900741 -
Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol
J Cell Biol, 113 (5), 1025-32
PubMed 2040642 -
Elimination of the disulphide bridge in fragment B of diphtheria toxin: effect on membrane insertion, channel formation, and ATP binding
Mol Microbiol, 5 (3), 595-606
PubMed 1646374 -
Athymic rats in preclinical immunodiagnostic studies
Anticancer Res, 11 (2), 649-55
PubMed 2064318 -
Immunomagnetic removal of L1210V leukemic cells from mouse bone marrow ex vivo
Arch Immunol Ther Exp (Warsz), 39 (3), 235-41
PubMed 1810216 -
Internalization and action of an immunotoxin containing mistletoe lectin A-chain
Cancer Res, 51 (3), 916-20
PubMed 1988131
Publications 1990
-
Amplification and protein over-expression of the neu/HER-2/c-erbB-2 protooncogene in human breast carcinomas: relationship to loss of gene sequences on chromosome 17, family history and prognosis
Br J Cancer, 62 (4), 585-90
PubMed 1977466 -
Nude rat model for studying metastasis of human tumor cells to bone and bone marrow
J Natl Cancer Inst, 82 (5), 408-12
PubMed 2304088 -
Translocation of diphtheria toxin to the cytosol and formation of cation selective channels
J Physiol (Paris), 84 (3), 191-6
PubMed 1705980 -
Protein toxins with intracellular targets
Microb Pathog, 8 (3), 163-8
PubMed 1696341 -
Mouse L1210V leukemia as a model to analyse efficiency of leukemic cell elimination by immunotoxin, antibody and complement, and cytostatic agents
In Vivo, 4 (3), 209-13
PubMed 2133264 -
Selective modulation of the endocytic uptake of ricin and fluid phase markers without alteration in transferrin endocytosis
J Biol Chem, 265 (11), 6382-8
PubMed 1969411 -
Role of Na(+)-H+ and Cl(-)-HCO3- antiports in the regulation of cytosolic pH near neutrality
Am J Physiol, 258 (6 Pt 1), C1117-26
PubMed 2163200 -
Regulation of Na+/H+ and Cl-/HCO3- antiports in Vero cells
J Cell Physiol, 143 (1), 178-87
PubMed 2156872 -
Endocytosis, intracellular transport and transcytosis of the toxic protein ricin by a polarized epithelium
Eur J Cell Biol, 51 (1), 96-109
PubMed 2328741
Publications 1989
-
Internalized ricin and the plasma membrane glycoprotein MAM-6 colocalize in the trans-Golgi network of T47D human breast carcinoma cells
Exp Cell Res, 185 (2), 373-86
PubMed 2689197 -
Monoclonal antibodies against human haptoglobin
Hybridoma, 8 (5), 551-60
PubMed 2478448 -
A human tumor lung metastasis model in athymic nude rats
Cancer Res, 49 (18), 5148-52
PubMed 2766284 -
AN ULTRASTRUCTURAL-STUDY OF BENIGN AND MALIGNANT BREAST EPITHELIAL-CELLS - A SEARCH FOR TONOFILAMENTS
J. Submicrosc. Cytol. Pathol., 21 (3), 469-474 -
Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants
EMBO J, 8 (10), 2843-8
PubMed 2684631 -
Role of anions in low pH-induced translocation of diphtheria toxin
J Biol Chem, 264 (19), 11367-72
PubMed 2500440 -
Translocation of diphtheria toxin A-fragment to the cytosol. Role of the site of interfragment cleavage
J Biol Chem, 264 (26), 15709-13
PubMed 2768283 -
Low-density-lipoprotein receptors in different rabbit liver cells
Biochem J, 261 (2), 587-93
PubMed 2549976 -
Immunotoxins--entry into cells and mechanisms of action
Immunol Today, 10 (9), 291-5
PubMed 2686677 -
FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
J. Biol. Chem., 264 (22), 12749-12751 -
Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
J Biol Chem, 264 (22), 12747-51
PubMed 2753882 -
The Thomsen-Friedenreich antigen on human urothelial cell lines detectable by peanut lectin and monoclonal antibody raised against human glycophorin A
Anticancer Res, 9 (1), 103-7
PubMed 2650614 -
Endocytosis from coated pits of Shiga toxin: a glycolipid-binding protein from Shigella dysenteriae 1
J Cell Biol, 108 (4), 1331-43
PubMed 2564398 -
Control of coated-pit function by cytoplasmic pH
Methods Cell Biol, 32, 365-82
PubMed 2575206 -
Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin
EMBO J, 8 (10), 2849-53
PubMed 2479538 -
Effect of anti-inflammatory analgesic drugs on the regulation of cytosolic pH by anion antiport
J Pharmacol Exp Ther, 248 (3), 1197-206
PubMed 2703970 -
Inhibition of chloride/bicarbonate antiports in monkey kidney cells (Vero) by non-steroidal anti-inflammatory drugs
Biochem Pharmacol, 38 (20), 3583-91
PubMed 2818647 -
The ways of endocytosis
Int Rev Cytol, 117, 131-77
PubMed 2573583 -
[Endocytosis, intracellular transport and sorting of proteins]
Nord Med, 104 (1), 9-11
PubMed 2911460 -
Specific killing of mouse leukemic cells with ricin A-chain immunotoxin
Arch Immunol Ther Exp (Warsz), 37 (1-2), 101-13
PubMed 2619494
Publications 1988
-
Degradation of the human erythrocyte membrane band 3 studied with monoclonal antibody directed against an epitope on the cytoplasmic fragment of band 3
Eur J Biochem, 174 (4), 647-54
PubMed 2455637 -
Neuron specific enolase-positive breast carcinomas
Histol Histopathol, 3 (1), 97-102
PubMed 2980214 -
Extrapulmonary, tissue-specific metastasis formation in nude mice injected with FEMX-I human melanoma cells
Cancer Res, 48 (15), 4382-8
PubMed 3390834 -
Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor
EMBO J, 7 (13), 4119-27
PubMed 3266596 -
Characterization of a toxic lectin in Iscador, a mistletoe preparation with alleged cancerostatic properties
Oncology, 45 (3), 172-9
PubMed 3368193 -
Low pH-induced release of diphtheria toxin A-fragment in Vero cells. Biochemical evidence for transfer to the cytosol
J Biol Chem, 263 (5), 2518-25
PubMed 3339019 -
NEURO-ENDOCRINE ACTIVITY IN METASTATIC BREAST CARCINOMAS
APMIS, 96 2, 204-214 -
Diphtheria toxin entry: protein translocation in the reverse direction
Trends Biochem Sci, 13 (9), 348-51
PubMed 3072713 -
How protein toxins enter and kill cells
Cancer Treat Res, 37, 39-73
PubMed 2908634 -
Role of chloride/bicarbonate antiport in the control of cytosolic pH. Cell-line differences in activity and regulation of antiport
J Biol Chem, 263 (23), 11117-25
PubMed 3403517 -
Diphtheria toxin-induced channels in Vero cells selective for monovalent cations
J Biol Chem, 263 (25), 12352-9
PubMed 2457582 -
Inhibition of endocytosis from coated pits by acidification of the cytosol
J Cell Biochem, 36 (1), 73-81
PubMed 2893802 -
Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane
J Biol Chem, 263 (26), 13449-55
PubMed 3417666 -
Estimation of the amount of internalized ricin that reaches the trans-Golgi network
J Cell Biol, 106 (2), 253-67
PubMed 2892843 -
Two monoclonal antibodies recognizing different epitopes of blood group N antigen
Arch Immunol Ther Exp (Warsz), 36 (5), 623-32
PubMed 2478103
Publications 1987
-
Selective localisation of two radiolabelled anti-sarcoma monoclonal antibodies in human osteosarcoma xenografts
Br J Cancer, 56 (1), 21-5
PubMed 3476143 -
Studies on the mechanism of action of abrin-9.2.27 immunotoxin in human melanoma cell lines
Cancer Res, 47 (23), 6243-7
PubMed 2445469 -
Mitozolomide (NSC 353451), a new active drug in the treatment of malignant melanoma. Phase II trial in patients with advanced disease
Br J Cancer, 55 (4), 433-5
PubMed 3580266 -
Chromosome 13 instability and esterase D expression in an osteosarcoma cell line
Cancer Genet Cytogenet, 24 (2), 327-34
PubMed 2878716 -
Selective inhibition of sodium-linked and sodium-independent bicarbonate/chloride antiport in Vero cells
J Biol Chem, 262 (16), 7486-91
PubMed 3584123 -
Effect of reduced endocytosis induced by hypotonic shock and potassium depletion on the infection of Hep 2 cells by picornaviruses
J Cell Physiol, 131 (1), 14-22
PubMed 3032992 -
Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport
J Cell Physiol, 131 (1), 6-13
PubMed 3571337 -
Cell-mediated reduction of the interfragment disulfide in nicked diphtheria toxin. A new system to study toxin entry at low pH
J Biol Chem, 262 (21), 10339-45
PubMed 3112141 -
Closing in on ricin action
Nature, 328 (6130), 474-5
PubMed 3614350 -
Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH
J Cell Physiol, 132 (2), 192-202
PubMed 3624315 -
Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines
Biochemistry, 26 (10), 2778-85
PubMed 3606992 -
Ionic requirements for entry of Shiga toxin from Shigella dysenteriae 1 into cells
Infect Immun, 55 (2), 298-303
PubMed 3542829 -
Pseudomonas toxin binds triton X-114 at low pH
Biochem J, 245 (3), 899-901
PubMed 3117052 -
Acidification of the cytosol inhibits endocytosis from coated pits
J Cell Biol, 105 (2), 679-89
PubMed 2887575 -
Bicarbonate/chloride antiport in Vero cells: I. Evidence for both sodium-linked and sodium-independent exchange
J Cell Physiol, 132 (2), 183-91
PubMed 3624314 -
Delivery of internalized ricin from endosomes to cisternal Golgi elements is a discontinuous, temperature-sensitive process
Exp Cell Res, 171 (1), 137-52
PubMed 3622628 -
Formation and activity of covalent conjugates of poliovirus and ligands binding to cell surface structures
Exp Cell Res, 170 (2), 483-90
PubMed 3036553
Publications 1986
-
Unexpected expression of the 250 kD melanoma-associated antigen in human sarcoma cells
Br J Cancer, 53 (6), 839-41
PubMed 3718838 -
VALUE OF HYDROXYPROLINE MEASUREMENTS IN THE ASSESSMENT OF LATE RADIATION ENTEROPATHY
ACTA ONCOL, 25 (2), 137-142 -
Mycobacterium bovis BCG-induced human T-cell clones from BCG-vaccinated healthy subjects: antigen specificity and lymphokine production
Infect Immun, 53 (3), 491-7
PubMed 2427449 -
Interactions between diphtheria toxin entry and anion transport in vero cells. III. Effect on toxin binding and anion transport of tumor-promoting phorbol esters, vanadate, fluoride, and salicylate
J Biol Chem, 261 (4), 1562-9
PubMed 3632976 -
Interactions between diphtheria toxin entry and anion transport in Vero cells. I. Anion antiport in Vero cells
J Biol Chem, 261 (4), 1542-52
PubMed 3944100 -
Interactions between diphtheria toxin entry and anion transport in Vero cells. II. Inhibition of anion antiport by diphtheria toxin
J Biol Chem, 261 (4), 1553-61
PubMed 3944101 -
pH-regulated anion antiport in nucleated mammalian cells
J Cell Biol, 102 (3), 967-71
PubMed 3949885 -
Interactions between diphtheria toxin entry and anion transport in Vero cells. IV. Evidence that entry of diphtheria toxin is dependent on efficient anion transport
J Biol Chem, 261 (4), 1570-5
PubMed 2418015 -
REQUIREMENT OF A TRANSMEMBRANE PH GRADIENT FOR THE ENTRY OF DIPHTHERIA-TOXIN INTO CELLS AT LOW PH
J. Biol. Chem., 261 (25), 1639-1644 -
Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin
Cancer Res, 46 (12 Pt 1), 6418-22
PubMed 3096563 -
Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH
J Biol Chem, 261 (25), 11639-44
PubMed 3745160 -
Routing of internalized ricin and ricin conjugates to the Golgi complex
J Cell Biol, 102 (1), 37-47
PubMed 3001103
Publications 1985
-
Entry of diphtheria toxin linked to concanavalin A into primate and murine cells
J Cell Physiol, 122 (2), 193-9
PubMed 3844014 -
Tumor-promoting phorbol esters and vanadate alter the sensitivity of HeLa S3 cells to poliovirus type 1
Exp Cell Res, 160 (1), 240-4
PubMed 2995095 -
Evidence that membrane phospholipids and protein are required for binding of diphtheria toxin in Vero cells
Biochim Biophys Acta, 846 (3), 334-41
PubMed 4041483 -
ENTRY MECHANISMS OF PROTEIN TOXINS AND PICORNAVIRUSES
Biochem. Soc. Symp. (50), 171-191 -
Entry mechanisms of protein toxins and picornaviruses
Biochem Soc Symp, 50, 171-91
PubMed 3915869 -
Effect of the chaotropic anions thiocyanate and perchlorate on the entry of ricin into Vero cells
Biochem J, 228 (2), 521-3
PubMed 2990449 -
Effect of potassium depletion of cells on their sensitivity to diphtheria toxin and pseudomonas toxin
J Cell Physiol, 124 (1), 54-60
PubMed 3930519 -
Properties of volkensin, a toxic lectin from Adenia volkensii
J Biol Chem, 260 (27), 14589-95
PubMed 3932357 -
PROPERTIES OF VOLKENSIN, A TOXIC LECTIN FROM ADENIA-VOLKENSII
J. Biol. Chem., 260 (27), 4589-4595 -
Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells. Intracellular routing to vacuolar and tubulo-vesicular portions of the endosomal system
Exp Cell Res, 159 (2), 287-304
PubMed 2863159 -
Characteristics of human tumour xenografts transplanted under the renal capsule of immunocompetent mice
Br J Cancer, 51 (3), 347-56
PubMed 3970811
Publications 1984
-
Analysis of heterokaryons and progeny cell hybrids isolated in the absence and in the presence of selective media
Cell Biol Int Rep, 8 (7), 599-606
PubMed 6744432 -
Phenotypes of cell hybrids formed by fusion of normal and Rous sarcoma virus transformed cells
Cell Biol Int Rep, 8 (7), 607-13
PubMed 6086159 -
Stable quantitative differences of antigen expression in human melanoma cells isolated by flow cytometric cell sorting
Int J Cancer, 34 (4), 507-12
PubMed 6386700 -
Antigen expression in human melanoma cells in relation to growth conditions and cell-cycle distribution
Int J Cancer, 33 (2), 167-71
PubMed 6693198 -
Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH
J Cell Biol, 98 (4), 1194-200
PubMed 6325467 -
Requirements for entry of poliovirus RNA into cells at low pH
EMBO J, 3 (9), 1945-50
PubMed 6092049 -
Different pH requirements for entry of the two picornaviruses, human rhinovirus 2 and murine encephalomyocarditis virus
Virology, 139 (2), 346-57
PubMed 6097029 -
Dimethyl sulphoxide protects cells against polypeptide toxins and poliovirus
Biochem J, 219 (3), 935-40
PubMed 6331401 -
Anion requirement and effect of anion transport inhibitors on the response of vero cells to diphtheria toxin and modeccin
J Cell Physiol, 119 (1), 7-14
PubMed 6707104 -
Receptor-mediated entry of protein toxins into cells
Acta Histochem Suppl, 29, 79-94
PubMed 6144140 -
Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments
J Cell Biol, 98 (3), 963-70
PubMed 6699094 -
Calmodulin antagonists sensitize cells to pseudomonas toxin
J Cell Physiol, 119 (1), 15-22
PubMed 6707099 -
Effect of malignant transformation, retinoic acid, trifluoperazine, and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W7) on the sensitivity of rodent cells to Pseudomonas toxin
Cancer Res, 44 (11), 4919-23
PubMed 6435858 -
Multicellular spheroids grown directly from human tumour material
Int J Cancer, 34 (1), 21-6
PubMed 6746116 -
Reduced antineoplastic activity in mice of cisplatin administered with high salt concentration in the vehicle
J Natl Cancer Inst, 73 (3), 743-52
PubMed 6590919
Publications 1983
-
Animal toxicity of Shigella dysenteriae cytotoxin: evidence that the neurotoxic, enterotoxic, and cytotoxic activities are due to one toxin
J Immunol, 130 (1), 380-4
PubMed 6336624 -
Entry of Shigella dysenteriae toxin into HeLa cells
Infect Immun, 42 (2), 771-7
PubMed 6358031 -
DANCYLCADAVERINE ELIMINATES CALMODULIN STIMULATION OF PHOSPHODIESTERASE
Biochem. Biophys. Res. Commun., 117 (2), 562-567 -
Dansylcadaverine eliminates calmodulin stimulation of phosphodiesterase
Biochem Biophys Res Commun, 117 (2), 562-7
PubMed 6318763 -
Preparation and properties of a hybrid toxin of modeccin A-chain and ricin B-chain
Biochim Biophys Acta, 761 (3), 296-302
PubMed 6652111
Publications 1982
-
The toxic lectin modeccin
Methods Enzymol, 83, 357-62
PubMed 6178935 -
Isolation and characterization of viscumin, a toxic lectin from Viscum album L. (mistletoe)
J Biol Chem, 257 (22), 13263-70
PubMed 7142144 -
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles
J Biol Chem, 257 (13), 7504-13
PubMed 7085634 -
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium
J Biol Chem, 257 (13), 7495-503
PubMed 6806276 -
Action of viscumin, a toxic lectin from mistletoe, on cells in culture
J Biol Chem, 257 (22), 13271-7
PubMed 7142145 -
Preparation and properties of chimeric toxins prepared from the constituent polypeptides of diphtheria toxin and ricin. Evidence for entry of ricin A-chain via the diphtheria toxin pathway
J Biol Chem, 257 (16), 9733-9
PubMed 7107588
Publications 1981
-
Polypeptide synthesis by mitoplasts isolated from mouse liver
Exp Cell Res, 132 (2), 265-72
PubMed 7215445 -
Radioimmunoassays of abrin and ricin in blood
J Toxicol Environ Health, 8 (3), 409-17
PubMed 7345165 -
Directing toxins to cancer cells
Nature, 290 (5802), 84
PubMed 7207602 -
Chimeric toxins
Pharmacol Ther, 15 (3), 355-81
PubMed 7345440 -
Subunit structure of Shigella cytotoxin
J Biol Chem, 256 (16), 8732-8
PubMed 7021550 -
The cytotoxic activity of Shigella toxin. Evidence for catalytic inactivation of the 60 S ribosomal subunit
J Biol Chem, 256 (16), 8739-44
PubMed 6894922 -
Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule
J Biol Chem, 256 (17), 9068-76
PubMed 7263699 -
Effects of retinoids and phorbol esters on the sensitivity of different cell lines to the polypeptide toxins modeccin, abrin, ricin and diphtheria toxin
Biochem J, 194 (3), 821-7
PubMed 7306026
Publications 1980
-
Interaction of Shigella shigae cytotoxin with receptors on sensitive and insensitive cells
J Recept Res, 1 (2), 199-213
PubMed 6895387 -
Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells
Exp Cell Res, 126 (2), 321-6
PubMed 7363949 -
Pathways involved in fluid phase and adsorptive endocytosis in neuroblastoma
J Cell Biol, 87 (3 Pt 1), 579-88
PubMed 7462317 -
Isolation and characterization of Shigella shigae cytotoxin
J Biol Chem, 255 (1), 284-9
PubMed 7350160 -
Corneal Changes During Chloroquine Treatment: An investigation of 70 patients with chronic rheumatoid arthritis receiving chloroquine treatment
Scand J Rheumatol, 9 (1), 150-6
PubMed 19919350 -
[Receptors for polypeptide hormones]
Tidsskr Nor Laegeforen, 100 (14), 964-6, 970
PubMed 6250247 -
[Intracellular mediators for polypeptide hormones]
Tidsskr Nor Laegeforen, 100 (15), 1021-23
PubMed 6250248 -
Diphtheria toxin entry into cells is facilitated by low pH
J Cell Biol, 87 (3 Pt 1), 828-32
PubMed 7462324 -
Gelonin, a new inhibitor of protein synthesis, nontoxic to intact cells. Isolation, characterization, and preparation of cytotoxic complexes with concanavalin A
J Biol Chem, 255 (14), 6947-53
PubMed 7391060 -
Human embryonal carcinoma grown in athymic mice and in vitro
Cancer Res, 40 (3), 949-53
PubMed 7471109 -
A human melanoma cell line established from xenograft in athymic mice
Br J Cancer, 41 (5), 724-33
PubMed 7426299 -
In vitro sensitivity of human melanoma xenografts to cytotoxic drugs. Correlation with in vivo chemosensitivity
Int J Cancer, 26 (6), 717-22
PubMed 7216540
Publications 1979
-
Fidelity of protein synthesis in vitro is increased in the presence of spermidine
FEBS Lett, 101 (1), 93-6
PubMed 446744 -
Elongation-factor-2-induced sensitization of ribosomes to modeccin. Evidence for specific binding of elongation factor 2 to ribosomes in the absence of nucleotides
Eur J Biochem, 93 (3), 447-52
PubMed 421687 -
Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells
Exp Cell Res, 121 (1), 15-25
PubMed 446525 -
Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin modeccin into HeLa cells
Biochem Biophys Res Commun, 90 (2), 648-55
PubMed 508328
Publications 1978
-
Toxic and nontoxic lectins from Abrus precatorius
Methods Enzymol, 50, 323-30
PubMed 661585 -
Ricin and ricinus agglutinin, toxic lectins from castor bean
Methods Enzymol, 50, 330-5
PubMed 661586 -
Purification and characterization of the highly toxic lectin modeccin
J Biol Chem, 253 (14), 5069-73
PubMed 97288 -
ABRIN AND RICIN-2 TOXIC LECTINS
Trends Biochem.Sci., 3 (1), 7-10 -
On the mechanism of toxin resistance in cell variants resistant to abrin and ricin
Eur J Biochem, 88 (1), 7-15
PubMed 566668 -
MECHANISM OF TOXIN RESISTANCE IN CELL VARIANTS RESISTANT TO ABRIN AND RICIN
Eur. J. Biochem., 88 (1), 7-15 -
Properties and action mechanism of the toxic lectin modeccin: interaction with cell lines resistant to modeccin, abrin, and ricin
J Supramol Struct, 9 (1), 15-25
PubMed 732310 -
[Teratocarcinoma as a model system in studies of malignancy and differentiation]
Tidsskr Nor Laegeforen, 98 (22), 998-1001
PubMed 684708 -
Cell density affects the binding of the toxic lectin abrin to HeLa cells in monolayer cultures
FEBS Lett, 89 (2), 233-6
PubMed 658411 -
Interactions between abrus lectins and Sephadex particles possessing immobilized desialylated fetuin. Model studies of the interaction of lectins with cell surface receptors
Eur J Biochem, 88 (1), 307-13
PubMed 78847 -
Binding, uptake and degradation of the toxic proteins abrin and ricin by toxin-resistant cell variants
Eur J Biochem, 82 (1), 13-23
PubMed 620666 -
Chemical modifications of the toxic lectins abrin and ricin
Eur J Biochem, 84 (2), 323-31
PubMed 639792 -
Inhibitory effects of the new mitotic inhibitor 5-chloropyrimidin-2-one and of vincristine on human cells in vitro
Cancer Res, 38 (3), 560-5
PubMed 626961
Publications 1977
-
Correlation of inhibition of ribosomal GTPase and protein synthesis by abrin and ricin
Biochem Biophys Res Commun, 75 (4), 845-50
PubMed 193503 -
[Research in clinical chemistry and clinical chemistry in research]
Med Welt, 28 (29), 1243-6
PubMed 895462 -
Studies on the accessability of ribosomes to inactivation by the toxic lectins abrin and ricin
Eur J Biochem, 74 (2), 209-15
PubMed 856578 -
STUDIES ON ACCESSIBILITY OF RIBOSOMES TO INACTIVATION BY TOXIC LECTINS ABRIN AND RICIN
Eur. J. Biochem., 74 (2), 209-215 -
Inhibitory effect of abrin and ricin on the growth of transplantable murine tumors and of abrin on human cancers in nude mice
Cancer Res, 37 (12), 4559-67
PubMed 922739 -
MODECCIN - PLANT TOXIN INHIBITING PROTEIN-SYNTHESIS
Biochem. Biophys. Res. Commun., 79 (4), 1176-1183 -
Modeccin--a plant toxin inhibiting protein synthesis
Biochem Biophys Res Commun, 79 (4), 1176-83
PubMed 603653 -
Effect of abrin on peptide chain initiation
Eur J Biochem, 79 (2), 559-64
PubMed 243461
Publications 1976
-
Protective effect of elongation factor 2 on the inactivation of ribosomes by the toxic lectins abrin and ricin
Eur J Biochem, 64 (2), 437-43
PubMed 1278169 -
Toxicity, distribution and elimination of the cancerostatic lectins abrin and ricin after parenteral injection into mice
Br J Cancer, 34 (4), 418-25
PubMed 974006 -
ABRIN AND RICIN - STRUCTURE AND MECHANISM OF ACTION OF 2 TOXIC LECTINS
Bull. Inst. Pasteur, 74 (1), 85-99 -
Rates of different steps involved in the inhibition of protein synthesis by the toxic lectins abrin and ricin
J Biol Chem, 251 (13), 3985-92
PubMed 932017 -
Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells
J Biol Chem, 251 (13), 3977-84
PubMed 6468
Publications 1975
-
On the mechanism of protein-synthesis inhibition by abrin and ricin. Inhibition of the GTP-hydrolysis site on the 60-S ribosomal subunit
Eur J Biochem, 59 (2), 573-80
PubMed 128455 -
MECHANISM OF PROTEIN-SYNTHESIS INHIBITION BY ABRIN AND RICIN - INHIBITION OF GTP-HYDROLYSIS SITE ON 60-S RIBOSOMAL-SUBUNIT
Eur. J. Biochem., 59 (2), 573-580 -
Stimulation of human lymphocytes by galactose-specific abrus and ricinus lectins
J Immunol, 115 (4), 1045-8
PubMed 1176765 -
INTERACTIONS BETWEEN RICINUS AGGLUTININ AND HUMAN PLASMA-PROTEINS
Scand. J. Immunol. (2), 125-134 -
Cleavage of adenovirus-5 DNA by an endonuclease from Haemophilus parainfluenzae
FEBS Lett, 57 (2), 153-7
PubMed 1175785 -
Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chains
Eur J Biochem, 60 (1), 281-8
PubMed 1204642 -
Studies on the structure and properties of the lectins from Abrus precatorius and Ricinus communis
Biochim Biophys Acta, 405 (1), 1-10
PubMed 1174560 -
Conformation-dependent antigenic determinants in the toxic lectin ricin
J Immunol, 114 (6), 1743-8
PubMed 47877 -
Interactions between ricinus agglutinin and human IgM and IgG
Scand J Immunol, 4 (3), 287-94
PubMed 1080291
Publications 1974
-
Lectins from Abrus precatorius and Ricinus communis. II. Hybrid toxins and their interaction with chain-specific antibodies
J Immunol, 113 (3), 842-7
PubMed 4414071 -
Clinical significance of estrogen receptors in human breast cancer
Biomedicine, 20 (6), 377-83
PubMed 4376029 -
Mechanism of action of the toxic lectins abrin and ricin
Nature, 249 (458), 627-31
PubMed 4857870 -
Isolation and comparison of galactose-binding lectins from Abrus precatorius and Ricinus communis
J Biol Chem, 249 (3), 803-10
PubMed 4811904 -
Lectins from Abrus precatorius and Ricinus communis. I. Immunochemical relationships between toxins and agglutinins
J Immunol, 113 (3), 835-41
PubMed 4213214 -
On the toxic proteins abrin and ricin. Studies of their binding to and entry into Ehrlich ascites cells
J Biol Chem, 249 (11), 3557-62
PubMed 4208663 -
TOXIC PROTEINS ABRIN AND RICIN - STUDIES OF THEIR BINDING TO AND ENTRY INTO EHRLICH ASCITES-CELLS
J. Biol. Chem., 249 (11), 3557-3562
Publications 1973
-
[Gene activation and mRNA synthesis in higher organisms]
Tidsskr Nor Laegeforen, 93 (16), 1230-5
PubMed 4356591 -
[Diphtheria toxin--a specific inhibitor of protein synthesis]
Tidsskr Nor Laegeforen, 93 (4), 223-7
PubMed 4691026 -
INACTIVATION OF EUKARYOTIC RIBOSOMES BY TOXIC PLANT PROTEINS ABRIN AND RICIN
Mol. Biol. Rep., 1 (1), 15-20 -
Isolation and properties of abrin: a toxic protein inhibiting protein synthesis. Evidence for different biological functions of its two constituent-peptide chains
Eur J Biochem, 35 (1), 179-85
PubMed 4123356 -
Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis
Biochemistry, 12 (16), 3121-6
PubMed 4730499 -
Content of estrogen receptors in human breast cancer
Eur J Cancer, 9 (5), 353-7
PubMed 4355726
Publications 1972
-
[Iridocyclitis with juvenile rheumatoid arthritis]
Tidsskr Nor Laegeforen, 12 (13), 922-3
PubMed 5063957 -
Binding of rat liver ribosomes to nuclear complementary RNA
Biochim Biophys Acta, 281 (2), 270-6
PubMed 4629425 -
Antigenic difference between informofers and protein bound to polyribosomal mRNA from rat liver
Nat New Biol, 240 (98), 90-2
PubMed 4117892 -
Toxic proteins inhibiting protein synthesis
Naturwissenschaften, 59 (11), 497-502
PubMed 4657651 -
Deoxycholate-induced release of monosomes from rat liver polyribosomes
Biochim Biophys Acta, 272 (1), 75-80
PubMed 5043716 -
Inhibition of peptide chain elongation
Nature, 238 (5365), 459-61
PubMed 4561855 -
Ricin - a potent inhibitor of protein synthesis
FEBS Lett, 20 (3), 327-329
PubMed 11946449 -
Treatment of abrin and ricin with -mercaptoethanol opposite effects on their toxicity in mice and their ability to inhibit protein synthesis in a cell-free system
FEBS Lett, 28 (1), 48-50
PubMed 4646874 -
Possible function of the protein bound to nuclear complementary RNA
FEBS Lett, 20 (2), 181-183
PubMed 11946410 -
Protein synthesis in the presence of non-ionic detergents in a cell-free system from rabbit reticulocytes
Biochem J, 130 (1), 297-9
PubMed 4655435 -
Translation of mouse globin mRNA by isolated ribosomal subunits from rabbit reticulocytes
Biochim Biophys Acta, 272 (4), 663-6
PubMed 5050924
Publications 1971
-
On the mechanism of the inhibiting effect of aurin tricarboxylic acid on the binding of ribosomes to ribonucleic acids
FEBS Lett, 18 (1), 169-171
PubMed 11946112 -
Further studies on the protein bound to the messenger RNA in mammalian polysomes
Eur J Biochem, 23 (3), 557-63
PubMed 5003111 -
Characterization of the complex containing rapidly labelled RNA in EDTA-treated polyribosomes from rat liver
Eur J Biochem, 18 (2), 242-51
PubMed 5541508 -
Evidence that protein is bound to the rapidly labelled RNA in polyribosomes in vivo
Eur J Biochem, 23 (2), 248-52
PubMed 5003205 -
The isolation of polysomes from rat liver. Contamination by membrane proteins with high affinity to ribosomes
Biochim Biophys Acta, 232 (4), 705-16
PubMed 5556851




Go back
Print this page
E-mail this page
