Publications 2011

Agostinis P, Berg K, Cengel KA, Foster TH, Girotti AW, Gollnick SO, Hahn SM, Hamblin MR, Juzeniene A, Kessel D, Korbelik M, Moan J, Mroz P, Nowis D, Piette J, Wilson BC, Golab J (2011)
Photodynamic therapy of cancer: an update
CA Cancer J Clin, 61 (4), 250-81
PubMed 21617154

Berg K, Golab J, Korbelik M, Russell D (2011)
Drug delivery technologies and immunological aspects of photodynamic therapy
Photochem Photobiol Sci, 10 (5), 647-8
PubMed 21487635

Berg K, Nordstrand S, Selbo PK, Tran DT, Angell-Petersen E, Høgset A (2011)
Disulfonated tetraphenyl chlorin (TPCS2a), a novel photosensitizer developed for clinical utilization of photochemical internalization
Photochem Photobiol Sci, 10 (10), 1637-51
PubMed 21773635

Jerjes WK, Upile T, Wong BJ, Betz CS, Sterenborg HJ, Witjes MJ, Berg K, van Veen R, Biel MA, El-Naggar AK, Mosse CA, Olivo M, Richards-Kortum R, Robinson DJ, Rosen J, Yodh AG, Kendall C, Ilgner JF, Amelink A, Bagnato V, Barr H, Bolotine L, Bigio I, Chen Z, Choo-Smith LP et al. (2011)
The future of medical diagnostics: review paper
Head Neck Oncol, 3, 38
PubMed 21861912

Upile T, Jerjes WK, Sterenborg HJ, Wong BJ, El-Naggar AK, Ilgner JF, Sandison A, Witjes MJ, Biel MA, van Veen R, Hamdoon Z, Gillenwater A, Mosse CA, Robinson DJ, Betz CS, Stepp H, Bolotine L, McKenzie G, Barr H, Chen Z, Berg K, D'Cruz AK, Sudhoff H, Stone N, Kendall C et al. (2011)
At the frontiers of surgery: review
Head Neck Oncol, 3 (1), 7
PubMed 21306627

Weyergang A, Selbo PK, Berstad ME, Bostad M, Berg K (2011)
Photochemical internalization of tumor-targeted protein toxins
Lasers Surg Med, 43 (7), 721-33
PubMed 22057500

Publications 2010

Berg K, Berstad M, Prasmickaite L, Weyergang A, Selbo PK, Hedfors I, Høgset A (2010)
Photochemical internalization: a new tool for gene and oligonucleotide delivery
Top Curr Chem, 296, 251-81
PubMed 21504105

Berg K, Weyergang A, Prasmickaite L, Bonsted A, Høgset A, Strand MT, Wagner E, Selbo PK (2010)
Photochemical internalization (PCI): a technology for drug delivery
Methods Mol Biol, 635, 133-45
PubMed 20552345

Johansen P, Berg K, Selbo PK, Hofbauer GF (2010)
[Photochemical internalisation (PCI): a further development of photodynamic therapy for the treatment of skin cancer]
Praxis (Bern 1994), 99 (23), 1423-8
PubMed 21082595

Reiners JJ, Agostinis P, Berg K, Oleinick NL, Kessel D (2010)
Assessing autophagy in the context of photodynamic therapy
Autophagy, 6 (1), 7-18
PubMed 19855190

Selbo PK, Weyergang A, Høgset A, Norum OJ, Berstad MB, Vikdal M, Berg K (2010)
Photochemical internalization provides time- and space-controlled endolysosomal escape of therapeutic molecules
J Control Release, 148 (1), 2-12
PubMed 20600406

Woodhams J, Lou PJ, Selbo PK, Mosse A, Oukrif D, MacRobert A, Novelli M, Peng Q, Berg K, Bown SG (2010)
Intracellular re-localisation by photochemical internalisation enhances the cytotoxic effect of gelonin--quantitative studies in normal rat liver
J Control Release, 142 (3), 347-53
PubMed 19932724

Publications 2009

Mojzisova H, Bonneau S, Maillard P, Berg K, Brault D (2009)
Photosensitizing properties of chlorins in solution and in membrane-mimicking systems
Photochem Photobiol Sci, 8 (6), 778-87
PubMed 19492105

Norum OJ, Bruland ØS, Gorunova L, Berg K (2009)
Photochemical internalization of bleomycin before external-beam radiotherapy improves locoregional control in a human sarcoma model
Int J Radiat Oncol Biol Phys, 75 (3), 878-85
PubMed 19665318

Norum OJ, Gaustad JV, Angell-Petersen E, Rofstad EK, Peng Q, Giercksky KE, Berg K (2009)
Photochemical internalization of bleomycin is superior to photodynamic therapy due to the therapeutic effect in the tumor periphery
Photochem Photobiol, 85 (3), 740-9
PubMed 19076314

Norum OJ, Giercksky KE, Berg K (2009)
Photochemical internalization as an adjunct to marginal surgery in a human sarcoma model
Photochem Photobiol Sci, 8 (6), 758-62
PubMed 19492102

Norum OJ, Selbo PK, Weyergang A, Giercksky KE, Berg K (2009)
Photochemical internalization (PCI) in cancer therapy: from bench towards bedside medicine
J Photochem Photobiol B, 96 (2), 83-92
PubMed 19467605

Selbo PK, Rosenblum MG, Cheung LH, Zhang W, Berg K (2009)
Multi-modality therapeutics with potent anti-tumor effects: photochemical internalization enhances delivery of the fusion toxin scFvMEL/rGel
PLoS One, 4 (8), e6691
PubMed 19690617

Upile T, Jerjes W, Sterenborg HJ, El-Naggar AK, Sandison A, Witjes MJ, Biel MA, Bigio I, Wong BJ, Gillenwater A, MacRobert AJ, Robinson DJ, Betz CS, Stepp H, Bolotine L, McKenzie G, Mosse CA, Barr H, Chen Z, Berg K, D'Cruz AK, Stone N, Kendall C, Fisher S, Leunig A et al. (2009)
Head & neck optical diagnostics: vision of the future of surgery
Head Neck Oncol, 1, 25
PubMed 19594907

Weyergang A, Berg K, Kaalhus O, Peng Q, Selbo PK (2009)
Photodynamic therapy targets the mTOR signaling network in vitro and in vivo
Mol Pharm, 6 (1), 255-64
PubMed 19125612

Publications 2008

Bonsted A, Wagner E, Prasmickaite L, Høgset A, Berg K (2008)
Photochemical enhancement of DNA delivery by EGF receptor targeted polyplexes
Methods Mol Biol, 434, 171-81
PubMed 18470645

Lai PS, Pai CL, Peng CL, Shieh MJ, Berg K, Lou PJ (2008)
Enhanced cytotoxicity of saporin by polyamidoamine dendrimer conjugation and photochemical internalization
J Biomed Mater Res A, 87 (1), 147-55
PubMed 18085655

Weyergang A, Kaalhus O, Berg K (2008)
Photodynamic therapy with an endocytically located photosensitizer cause a rapid activation of the mitogen-activated protein kinases extracellular signal-regulated kinase, p38, and c-Jun NH2 terminal kinase with opposing effects on cell survival
Mol Cancer Ther, 7 (6), 1740-50
PubMed 18566245

Weyergang A, Kaalhus O, Berg K (2008)
Photodynamic targeting of EGFR does not predict the treatment outcome in combination with the EGFR tyrosine kinase inhibitor Tyrphostin AG1478
Photochem Photobiol Sci, 7 (9), 1032-40
PubMed 18754049

Publications 2007

Berg K, Folini M, Prasmickaite L, Selbo PK, Bonsted A, Engesaeter BØ, Zaffaroni N, Weyergang A, Dietze A, Maelandsmo GM, Wagner E, Norum OJ, Høgset A (2007)
Photochemical internalization: a new tool for drug delivery
Curr Pharm Biotechnol, 8 (6), 362-72
PubMed 18289045

Folini M, Bandiera R, Millo E, Gandellini P, Sozzi G, Gasparini P, Longoni N, Binda M, Daidone MG, Berg K, Zaffaroni N (2007)
Photochemically enhanced delivery of a cell-penetrating peptide nucleic acid conjugate targeting human telomerase reverse transcriptase: effects on telomere status and proliferative potential of human prostate cancer cells
Cell Prolif, 40 (6), 905-20
PubMed 18021178

Peng Q, Berg K (2007)
Introduction to the special issue on photodynamic therapy and photodetection
Photochem. Photobiol. Sci., 6 (12), 1233

Weyergang A, Selbo PK, Berg K (2007)
Y1068 phosphorylation is the most sensitive target of disulfonated tetraphenylporphyrin-based photodynamic therapy on epidermal growth factor receptor
Biochem Pharmacol, 74 (2), 226-35
PubMed 17531956

Yip WL, Weyergang A, Berg K, Tønnesen HH, Selbo PK (2007)
Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells
Mol Pharm, 4 (2), 241-51
PubMed 17263556

Publications 2006

Berg K, Høgset A, Prasmickaite L, Weyergang A, Bonsted A, Dietze A, Lou PJ, Bown S, Norum OJ, Møllergard HM, Selbo PK (2006)
Photochemical internalization (PCI): A novel technology for activation of endocytosed therapeutic agents.
Med Laser Appl, 21, 239-251
PublikaID 73

Bonsted A, Engesaeter BØ, Høgset A, Berg K (2006)
Photochemically enhanced adenoviral transduction in a multicellular environment
Photochem Photobiol Sci, 5 (4), 411-21
PubMed 16583022

Bonsted A, Engesaeter BØ, Høgset A, Maelandsmo GM, Prasmickaite L, D'Oliveira C, Hennink WE, van Steenis JH, Berg K (2006)
Photochemically enhanced transduction of polymer-complexed adenovirus targeted to the epidermal growth factor receptor
J Gene Med, 8 (3), 286-97
PubMed 16342300

Dietze A, Selbo PK, Prasmickaite L, Weyergang A, Bonsted A, Engesaeter B, Hogset A, Berg K (2006)
Photochemical internalization (PCI): a new modality for light activation of endocytosed therapeuticals
J Environ Pathol Toxicol Oncol, 25 (1-2), 521-36
PubMed 16566739

Engesaeter BØ, Bonsted A, Lillehammer T, Engebraaten O, Berg K, Maelandsmo GM (2006)
Photochemically mediated delivery of AdhCMV-TRAIL augments the TRAIL-induced apoptosis in colorectal cancer cell lines
Cancer Biol Ther, 5 (11), 1511-20
PubMed 17012835

Engesaeter BØ, Tveito S, Bonsted A, Engebraaten O, Berg K, Maelandsmo GM (2006)
Photochemical treatment with endosomally localized photosensitizers enhances the number of adenoviruses in the nucleus
J Gene Med, 8 (6), 707-18
PubMed 16518880

Kloeckner J, Boeckle S, Persson D, Roedl W, Ogris M, Berg K, Wagner E (2006)
DNA polyplexes based on degradable oligoethylenimine-derivatives: combination with EGF receptor targeting and endosomal release functions
J Control Release, 116 (2), 115-22
PubMed 16959361

Lou PJ, Lai PS, Shieh MJ, Macrobert AJ, Berg K, Bown SG (2006)
Reversal of doxorubicin resistance in breast cancer cells by photochemical internalization
Int J Cancer, 119 (11), 2692-8
PubMed 16991130

Ndoye A, Dolivet G, Høgset A, Leroux A, Fifre A, Erbacher P, Berg K, Behr JP, Guillemin F, Merlin JL (2006)
Eradication of p53-mutated head and neck squamous cell carcinoma xenografts using nonviral p53 gene therapy and photochemical internalization
Mol Ther, 13 (6), 1156-62
PubMed 16564229

Prasmickaite L, Cekaite L, Hellum M, Hovig E, Høgset A, Berg K (2006)
Transcriptome changes in a colon adenocarcinoma cell line in response to photochemical treatment as used in photochemical internalisation (PCI)
FEBS Lett, 580 (24), 5739-46
PubMed 17007842

Prasmickaite L, Hellum M, Kaalhus O, Høgset A, Wagner E, Berg K (2006)
Photochemical internalization of transgenes controlled by the heat-shock protein 70 promoter
Photochem Photobiol, 82 (3), 809-16
PubMed 16420102

Selbo PK, Weyergang A, Bonsted A, Bown SG, Berg K (2006)
Photochemical internalization of therapeutic macromolecular agents: a novel strategy to kill multidrug-resistant cancer cells
J Pharmacol Exp Ther, 319 (2), 604-12
PubMed 16902053

Weyergang A, Selbo PK, Berg K (2006)
Photochemically stimulated drug delivery increases the cytotoxicity and specificity of EGF-saporin
J Control Release, 111 (1-2), 165-73
PubMed 16466823

Publications 2005

Berg K, Dietze A, Kaalhus O, Høgset A (2005)
Site-specific drug delivery by photochemical internalization enhances the antitumor effect of bleomycin
Clin Cancer Res, 11 (23), 8476-85
PubMed 16322311

Bonsted A, Høgset A, Hoover F, Berg K (2005)
Photochemical enhancement of gene delivery to glioblastoma cells is dependent on the vector applied
Anticancer Res, 25 (1A), 291-7
PubMed 15816550

Engesaeter BØ, Bonsted A, Berg K, Høgset A, Engebråten O, Fodstad Ø, Curiel DT, Maelandsmo GM (2005)
PCI-enhanced adenoviral transduction employs the known uptake mechanism of adenoviral particles
Cancer Gene Ther, 12 (5), 439-48
PubMed 15678152

Gederaas OA, Schønberg SA, Ramstad S, Berg K, Johnsson A, Krokan HE (2005)
Cell specific effects of polyunsaturated fatty acids on 5-aminolevulinic acid based photosensitization
Photochem Photobiol Sci, 4 (4), 383-9
PubMed 15803209

Publications 2004

Berg K, Selbo PK, Prasmickaite L, Høgset A (2004)
Photochemical drug and gene delivery
Curr Opin Mol Ther, 6 (3), 279-87
PubMed 15264430

Høgset A, Prasmickaite L, Selbo PK, Hellum M, Engesaeter BØ, Bonsted A, Berg K (2004)
Photochemical internalisation in drug and gene delivery
Adv Drug Deliv Rev, 56 (1), 95-115
PubMed 14706447

Kloeckner J, Prasmickaite L, Høgset A, Berg K, Wagner E (2004)
Photochemically enhanced gene delivery of EGF receptor-targeted DNA polyplexes
J Drug Target, 12 (4), 205-13
PubMed 15506169

Ndoye A, Bouali S, Dolivet G, Leroux A, Erbacher P, Behr JP, Berg K, Guillemin F, Merlin JL (2004)
Sustained gene transfer and enhanced cell death following glucosylated-PEI-mediated p53 gene transfer with photochemical internalisation in p53-mutated head and neck carcinoma cells
Int J Oncol, 25 (6), 1575-81
PubMed 15547693

Ndoye A, Merlin JL, Leroux A, Dolivet G, Erbacher P, Behr JP, Berg K, Guillemin F (2004)
Enhanced gene transfer and cell death following p53 gene transfer using photochemical internalisation of glucosylated PEI-DNA complexes
J Gene Med, 6 (8), 884-94
PubMed 15293347

Prasmickaite L, Høgset A, Engesaeter B BØ, Bonsted A, Berg K (2004)
Light-directed gene delivery by photochemical internalisation
Expert Opin Biol Ther, 4 (9), 1403-12
PubMed 15335308

Prasmickaite L, Høgset A, Olsen VM, Kaalhus O, Mikalsen SO, Berg K (2004)
Photochemically enhanced gene transfection increases the cytotoxicity of the herpes simplex virus thymidine kinase gene combined with ganciclovir
Cancer Gene Ther, 11 (7), 514-23
PubMed 15118758

Publications 2003

Berg K, Prasmickaite L, Selbo PK, Hellum M, Bonsted A, Høgset A (2003)
Photochemical internalization (PCI)--a novel technology for release of macromolecules from endocytic vesicles
Oftalmologia, 56 (1), 67-71
PubMed 12886687

Folini M, Berg K, Millo E, Villa R, Prasmickaite L, Daidone MG, Benatti U, Zaffaroni N (2003)
Photochemical internalization of a peptide nucleic acid targeting the catalytic subunit of human telomerase
Cancer Res, 63 (13), 3490-4
PubMed 12839932

Hellum M, Høgset A, Engesaeter BO, Prasmickaite L, Stokke T, Wheeler C, Berg K (2003)
Photochemically enhanced gene delivery with cationic lipid formulations
Photochem Photobiol Sci, 2 (4), 407-11
PubMed 12760539

Publications 2002

Høgset A, Engesaeter BO, Prasmickaite L, Berg K, Fodstad O, Maelandsmo GM (2002)
Light-induced adenovirus gene transfer, an efficient and specific gene delivery technology for cancer gene therapy
Cancer Gene Ther, 9 (4), 365-71
PubMed 11960287

Høgset A, Prasmickaite L, Hellum M, Engesaeter BO, Olsen VM, Tjelle TE, Wheeler CJ, Berg K (2002)
Photochemical transfection: a technology for efficient light-directed gene delivery
Somat Cell Mol Genet, 27 (1-6), 97-113
PubMed 12774944

Prasmickaite L, Høgset A, Berg K (2002)
Photochemical transfection. Light-induced, site-directed gene delivery
Methods Mol Med, 69, 123-35
PubMed 11987772

Prasmickaite L, Høgset A, Berg K (2002)
The role of the cell cycle on the efficiency of photochemical gene transfection
Biochim Biophys Acta, 1570 (3), 210-8
PubMed 12020812

Selbo PK, Høgset A, Prasmickaite L, Berg K (2002)
Photochemical internalisation: a novel drug delivery system
Tumour Biol, 23 (2), 103-12
PubMed 12065848

Publications 1998

Berg K, Maziere JC, Geze M, Santus R (1998)
Verapamil enhances the uptake and the photocytotoxic effect of PII, but not that of tetra(4-sulfonatophenyl)porphine
Biochim Biophys Acta, 1370 (2), 317-24
PubMed 9545591

Publications 1992

Berg K (1992)
The unpolymerized form of tubulin is the target for microtubule inhibition by photoactivated tetra(4-sulfonatophenyl)porphine
Biochim Biophys Acta, 1135 (2), 147-53
PubMed 1616935