Theodossis Athanassios Theodossiou
Position: Senior Researcher, Marie Curie IntraEuropean Fellow
Phone: +47 22781464
Email:
Room: K03 068
 

Author network for Theodossis Athanassios Theodossiou by COREMINE medical


Publications 2017

Katheder NS, Khezri R, O'Farrell F, Schultz SW, Jain A, Rahman MM, Schink KO, Theodossiou TA, Johansen T, Juhßsz G, Bilder D, Brech A, Stenmark H, Rusten TE (2017)
Microenvironmental autophagy promotes tumour growth
Nature, 541 (7637), 417-420
PubMed 28077876

Theodossiou TA, Olsen CE, Jonsson M, Kubin A, Hothersall JS, Berg K (2017)
The diverse roles of glutathione-associated cell resistance against hypericin photodynamic therapy
Redox Biol, 12, 191-197 (in press)
PubMed 28254657

Publications 2015

Pefkianakis EK, Theodossiou TA, Toubanaki DK, Karagouni E, Falaras P, Papadopoulos K, Vougioukalakis GC (2015)
A Family of Potent Ru(II) Photosensitizers with Enhanced DNA Intercalation: Bimodal Photokillers
Photochem Photobiol, 91 (5), 1191-202
PubMed 26118404

Theodossiou TA, Wńlchli S, Olsen CE, Skarpen E, Berg K (2015)
Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity
ACS Chem Biol, 11 (1), 251-62
PubMed 26569462

Publications 2014

Aggelidou C, Theodossiou TA, Gonšalves AR, Lampropoulou M, Yannakopoulou K (2014)
A versatile δ-aminolevulinic acid (ΑLA)-cyclodextrin bimodal conjugate-prodrug for PDT applications with the help of intracellular chemistry
Beilstein J Org Chem, 10, 2414-20
PubMed 25383111

Paleos CM, Sideratou Z, Theodossiou TA, Tsiourvas D (2014)
Carboxylated hydroxyethyl starch: a novel polysaccharide for the delivery of doxorubicin
Chem Biol Drug Des, 85 (5), 653-8
PubMed 25303215

Publications 2013

Aggelidou C, Theodossiou TA, Yannakopoulou K (2013)
Protoporphyrin IX-β-cyclodextrin bimodal conjugate: nanosized drug transporter and potent phototoxin
Photochem Photobiol, 89 (5), 1011-9
PubMed 23819797

Fraix A, Gonšalves AR, Cardile V, Graziano AC, Theodossiou TA, Yannakopoulou K, Sortino S (2013)
A multifunctional bichromophoric nanoaggregate for fluorescence imaging and simultaneous photogeneration of RNOS and ROS
Chem Asian J, 8 (11), 2634-41
PubMed 23788396

Piras L, Theodossiou TA, Manouilidou MD, Lazarou YG, Sortino S, Yannakopoulou K (2013)
S-nitroso-β-cyclodextrins as new bimodal carriers: preparation, detailed characterization, nitric-oxide release, and molecular encapsulation
Chem Asian J, 8 (11), 2768-78
PubMed 23894118

Theodossiou TA, Sideratou Z, Katsarou ME, Tsiourvas D (2013)
Mitochondrial delivery of doxorubicin by triphenylphosphonium-functionalized hyperbranched nanocarriers results in rapid and severe cytotoxicity
Pharm Res, 30 (11), 2832-42
PubMed 23921486

Publications 2012

Theodossiou TA, Yannakopoulou K, Aggelidou C, Hothersall JS (2012)
Tamoxifen subcellular localization; observation of cell-specific cytotoxicity enhancement by inhibition of mitochondrial ETC complexes I and III
Photochem Photobiol, 88 (4), 1016-22
PubMed 22428931

Publications 2011

Theodossiou TA, Sideratou Z, Tsiourvas D, Paleos CM (2011)
A novel mitotropic oligolysine nanocarrier: Targeted delivery of covalently bound D-Luciferin to cell mitochondria
Mitochondrion, 11 (6), 982-6
PubMed 21856448

Publications 2010

Sideratou Z, Tsiourvas D, Theodossiou T, Fardis M, Paleos CM (2010)
Synthesis and characterization of multifunctional hyperbranched polyesters as prospective contrast agents for targeted MRI
Bioorg Med Chem Lett, 20 (14), 4177-81
PubMed 20621729

Publications 2009

Theodossiou TA, Hothersall JS, De Witte PA, Pantos A, Agostinis P (2009)
The multifaceted photocytotoxic profile of hypericin
Mol Pharm, 6 (6), 1775-89
PubMed 19739671

Theodossiou TA, Tsiourvas D, Hothersall JS (2009)
Hypericin hydroquinone: potential as a red-far red photosensitizer?
Photochem Photobiol, 86 (1), 18-22
PubMed 20003155

Publications 2008

Galanou MC, Theodossiou TA, Tsiourvas D, Sideratou Z, Paleos CM (2008)
Interactive transport, subcellular relocation and enhanced phototoxicity of hypericin encapsulated in guanidinylated liposomes via molecular recognition
Photochem Photobiol, 84 (5), 1073-83
PubMed 18627515

Kontoyianni C, Sideratou Z, Theodossiou T, Tziveleka LA, Tsiourvas D, Paleos CM (2008)
A novel micellar PEGylated hyperbranched polyester as a prospective drug delivery system for paclitaxel
Macromol Biosci, 8 (9), 871-81
PubMed 18484566

Theodossiou TA, Galanou MC, Paleos CM (2008)
Novel amiodarone-doxorubicin cocktail liposomes enhance doxorubicin retention and cytotoxicity in DU145 human prostate carcinoma cells
J Med Chem, 51 (19), 6067-74
PubMed 18783209

Theodossiou TA, Pantos A, Tsogas I, Paleos CM (2008)
Guanidinylated dendritic molecular transporters: prospective drug delivery systems and application in cell transfection
ChemMedChem, 3 (11), 1635-43
PubMed 18985650

Theodossiou TA, Papakyriakou A, Hothersall JS (2008)
Molecular modeling and experimental evidence for hypericin as a substrate for mitochondrial complex III; mitochondrial photodamage as demonstrated using specific inhibitors
Free Radic Biol Med, 45 (11), 1581-90
PubMed 18852042

Publications 2007

Tsogas I, Sideratou Z, Tsiourvas D, Theodossiou TA, Paleos CM (2007)
Interactive transport of guanidinylated poly(propylene imine)-based dendrimers through liposomal and cellular membranes
Chembiochem, 8 (15), 1865-76
PubMed 17854019

Tsogas I, Theodossiou T, Sideratou Z, Paleos CM, Collet H, Rossi JC, Romestand B, Commeyras A (2007)
Interaction and transport of poly(L-lysine) dendrigrafts through liposomal and cellular membranes: the role of generation and surface functionalization
Biomacromolecules, 8 (10), 3263-70
PubMed 17880235

Publications 2006

Theodossiou TA, Noronha-Dutra A, Hothersall JS (2006)
Mitochondria are a primary target of hypericin phototoxicity: synergy of intracellular calcium mobilisation in cell killing
Int J Biochem Cell Biol, 38 (11), 1946-56
PubMed 16814590

Theodossiou TA, Thrasivoulou C, Ekwobi C, Becker DL (2006)
Second harmonic generation confocal microscopy of collagen type I from rat tendon cryosections
Biophys J, 91 (12), 4665-77
PubMed 17130233

Publications 2004

Theodossiou T, Spiro MD, Jacobson J, Hothersall JS, Macrobert AJ (2004)
Evidence for intracellular aggregation of hypericin and the impact on its photocytotoxicity in PAM 212 murine keratinocytes
Photochem Photobiol, 80 (3), 438-43
PubMed 15623327

Publications 2003

Mosse CA, Theodossiou T, Mills TN (2003)
A system to monitor for fibre breakage during photodynamic therapy with diffuser fibres
Lasers Med Sci, 18 (3), 162-4
PubMed 14505200

Theodossiou T, Hothersall JS, Woods EA, Okkenhaug K, Jacobson J, MacRobert AJ (2003)
Firefly luciferin-activated rose bengal: in vitro photodynamic therapy by intracellular chemiluminescence in transgenic NIH 3T3 cells
Cancer Res, 63 (8), 1818-21
PubMed 12702568

Publications 2002

Theodossiou T, MacRobert AJ (2002)
Comparison of the photodynamic effect of exogenous photoprotoporphyrin and protoporphyrin IX on PAM 212 murine keratinocytes
Photochem Photobiol, 76 (5), 530-7
PubMed 12462649

Theodossiou T, Rapti GS, Hovhannisyan V, Georgiou E, Politopoulos K, Yova D (2002)
Thermally induced irreversible conformational changes in collagen probed by optical second harmonic generation and laser-induced fluorescence
Lasers Med Sci, 17 (1), 34-41
PubMed 11845366

Publications 2001

Theodossiou T, Georgiou E, Hovhannisyan V, Yova D (2001)
Visual observation of infrared laser speckle patterns at half their fundamental wavelength
Lasers Med Sci, 16 (1), 34-9
PubMed 11486336

Yova D, Hovhannisyan V, Theodossiou T (2001)
Photochemical effects and hypericin photosensitized processes in collagen
J Biomed Opt, 6 (1), 52-7
PubMed 11178580