Tor Inge Tønnessen
Position: Group leader
Phone: +47 230 73692
Email:
Alternative email address: t.i.tonnessen@medisin.uio.no
 

Author network for Tor Inge Tønnessen by COREMINE medical


Publications 2017

Pischke SE, Gustavsen A, Orrem HL, Egge KH, Courivaud F, Fontenelle H, Despont A, Bongoni AK, Rieben R, Tønnessen TI, Nunn MA, Scott H, Skulstad H, Barratt-Due A, Mollnes TE (2017)
Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function
Basic Res Cardiol, 112 (3), 20
PubMed 28258298

Strand-Amundsen RJ, Reims HM, Tronstad C, Kalvøy H, Martinsen ØG, Høgetveit JO, Ruud TE, Tønnessen TI (2017)
Ischemic small intestine-in vivo versus ex vivo bioimpedance measurements
Physiol Meas, 38 (5), 715-728 (in press)
PubMed 28319030

Yang R, Tenhunen J, Tonnessen TI (2017)
HMGB1 and Histones Play a Significant Role in Inducing Systemic Inflammation and Multiple Organ Dysfunctions in Severe Acute Pancreatitis
Int J Inflam, 2017, 1817564
PubMed 28316860

Publications 2016

Lipcsey M, Tenhunen J, Sjölin J, Frithiof R, Bendel S, Flaatten H, Kawati R, Kuitunen A, Tønnessen TI, Rubertsson S (2016)
Abdominal Septic Shock - Endotoxin Adsorption Treatment (ASSET) - endotoxin removal in abdominal and urogenital septic shock with the Alteco® LPS Adsorber: study protocol for a double-blinded, randomized placebo-controlled trial
Trials, 17 (1), 587
PubMed 27931259

Strand-Amundsen RJ, Tronstad C, Kalvøy H, Gundersen Y, Krohn CD, Aasen AO, Holhjem L, Reims HM, Martinsen ØG, Høgetveit JO, Ruud TE, Tønnessen TI (2016)
In vivo characterization of ischemic small intestine using bioimpedance measurements
Physiol Meas, 37 (2), 257-75
PubMed 26805916

Tønnessen TI (2016)
[Not Available]
Tidsskr Nor Laegeforen, 136 (5), 380-1
PubMed 26983125

Yang R, Zhu S, Tonnessen TI (2016)
Ethyl pyruvate is a novel anti-inflammatory agent to treat multiple inflammatory organ injuries
J Inflamm (Lond), 13, 37
PubMed 27980458

Publications 2015

Fretland ÅA, Kazaryan AM, Bjørnbeth BA, Flatmark K, Andersen MH, Tønnessen TI, Bjørnelv GM, Fagerland MW, Kristiansen R, Øyri K, Edwin B (2015)
Open versus laparoscopic liver resection for colorectal liver metastases (the Oslo-CoMet Study): study protocol for a randomized controlled trial
Trials, 16, 73
PubMed 25872027

Haugaa H, Gómez H, Maberry DR, Holder A, Ogundele O, Quintero AM, Escobar D, Tønnessen TI, Airgood H, Dezfulian C, Kenny E, Shiva S, Zuckerbraun B, Pinsky MR (2015)
Effects of inhalation of low-dose nitrite or carbon monoxide on post-reperfusion mitochondrial function and tissue injury in hemorrhagic shock swine
Crit Care, 19, 184
PubMed 25899004

Hyler S, Pischke SE, Halvorsen PS, Espinoza A, Bergsland J, Tønnessen TI, Fosse E, Skulstad H (2015)
Continuous monitoring of regional function by a miniaturized ultrasound transducer allows early quantification of low-grade myocardial ischemia
J Am Soc Echocardiogr, 28 (4), 486-94
PubMed 25636368

Khan F, Pharo A, Lindstad JK, Mollnes TE, Tønnessen TI, Pischke SE (2015)
Effect of Perfusion Fluids on Recovery of Inflammatory Mediators in Microdialysis
Scand J Immunol, 82 (5), 467-75
PubMed 26099791

Publications 2014

Haugaa H, Taraldsrud E, Nyrerød HC, Tønnessen TI, Foss A, Solheim BG (2014)
Low incidence of hyperfibrinolysis and thromboembolism in 195 primary liver transplantations transfused with solvent/detergent-treated plasma
Clin Med Res, 12 (1-2), 27-32
PubMed 24415744

Pischke SE, Hyler S, Tronstad C, Bergsland J, Fosse E, Halvorsen PS, Skulstad H, Tønnessen TI (2014)
Myocardial tissue CO2 tension detects coronary blood flow reduction after coronary artery bypass in real-time†
Br J Anaesth, 114 (3), 414-22
PubMed 25392231

Yang R, Zou X, Tenhunen J, Zhu S, Kajander H, Koskinen ML, Tonnessen TI (2014)
HMGB1 neutralization is associated with bacterial translocation during acetaminophen hepatotoxicity
BMC Gastroenterol, 14, 66
PubMed 24708589

Publications 2013

Haugaa H, Almaas R, Thorgersen EB, Foss A, Line PD, Sanengen T, Bergmann GB, Ohlin P, Waelgaard L, Grindheim G, Pischke SE, Mollnes TE, Tønnessen TI (2013)
Clinical experience with microdialysis catheters in pediatric liver transplants
Liver Transpl, 19 (3), 305-14
PubMed 23193034

Holhjem L, Strand-Amundsen R, Aasmundtveit KE, Tonnessen TI (2013)
Development of a Conductometric Biocompatible Sensor For Detecting Ischemia
EUR MICROELECTRON PA

Publications 2012

Håugaa H, Thorgersen EB, Pharo A, Boberg KM, Foss A, Line PD, Sanengen T, Almaas R, Grindheim G, Pischke SE, Mollnes TE, Tønnessen TI (2012)
Early bedside detection of ischemia and rejection in liver transplants by microdialysis
Liver Transpl, 18 (7), 839-49
PubMed 22407878

Pischke SE, Tronstad C, Holhjem L, Halvorsen PS, Tønnessen TI (2012)
Perioperative detection of myocardial ischaemia/reperfusion with a novel tissue CO2 monitoring technology
Eur J Cardiothorac Surg, 42 (1), 157-63
PubMed 22290904

Pischke SE, Tronstad C, Holhjem L, Line PD, Haugaa H, Tønnessen TI (2012)
Hepatic and abdominal carbon dioxide measurements detect and distinguish hepatic artery occlusion and portal vein occlusion in pigs
Liver Transpl, 18 (12), 1485-94
PubMed 22961940

Sokolov A, Hellerud BC, Tønnessen TI, Johannessen EA, Mollnes TE (2012)
Activation of coagulation and platelets by candidate membranes of implantable devices in a whole blood model without soluble anticoagulant
J Biomed Mater Res A, 101 (2), 575-81
PubMed 22949225

Publications 2011

Barratt-Due A, Johansen HT, Sokolov A, Thorgersen EB, Hellerud BC, Reubsaet JL, Seip KF, Tønnessen TI, Lindstad JK, Pharo A, Castellheim A, Mollnes TE, Nielsen EW (2011)
The role of bradykinin and the effect of the bradykinin receptor antagonist icatibant in porcine sepsis
Shock, 36 (5), 517-23
PubMed 21921836

Krushinitskaya O, Tonnessen TI, Jakobsen H, Johannessen EA (2011)
Characterization of nanoporous membranes for implementation in an osmotic glucose sensor based on the concanavalin A-dextran affinity assay
J. Membr. Sci., 376 (1-2), 153-161

Krushinitskaya O, Tønnessen TI, Jakobsen H, Johannessen E (2011)
The assessment of potentially interfering metabolites and dietary components in blood using an osmotic glucose sensor based on the concanavalin A-dextran affinity assay
Biosens Bioelectron, 28 (1), 195-203
PubMed 21816599

Waelgaard L, Dahl BM, Kvarstein G, Tønnessen TI (2011)
Tissue gas tensions and tissue metabolites for detection of organ hypoperfusion and ischemia
Acta Anaesthesiol Scand, 56 (2), 200-9
PubMed 22103593

Publications 2010

Hellerud BC, Nielsen EW, Thorgersen EB, Lindstad JK, Pharo A, Tønnessen TI, Castellheim A, Mollnes TE, Brandtzaeg P (2010)
Dissecting the effects of lipopolysaccharides from nonlipopolysaccharide molecules in experimental porcine meningococcal sepsis
Crit Care Med, 38 (6), 1467-74
PubMed 20400898

Johannessen E, Krushinitskaya O, Sokolov A, Philipp H, Hoogerwerf A, Hinderling C, Kautio K, Lenkkeri J, Strömmer E, Kondratyev V, Tønnessen TI, Mollnes TE, Jakobsen H, Zimmer E, Akselsen B (2010)
Toward an injectable continuous osmotic glucose sensor
J Diabetes Sci Technol, 4 (4), 882-92
PubMed 20663452

Tronstad C, Pischke SE, Holhjem L, Tønnessen TI, Martinsen OG, Grimnes S (2010)
Early detection of cardiac ischemia using a conductometric pCO(2) sensor: real-time drift correction and parameterization
Physiol Meas, 31 (9), 1241-55
PubMed 20702916

Publications 2009

Kvarstein G, Måwe L, Indahl A, Hol PK, Tennøe B, Digernes R, Stubhaug A, Tønnessen TI, Beivik H (2009)
A randomized double-blind controlled trial of intra-annular radiofrequency thermal disc therapy--a 12-month follow-up
Pain, 145 (3), 279-86
PubMed 19647940

Kvarstein G, Måwe L, Indahl A, Hol PK, Tennøe B, Digernes R, Tønnessen TI, Beivik H, Stubhaug A (2009)
Placebo control--still the most ethical study design
Pain, 148 (1), 174-5
PubMed 19962241

Nielsen EW, Hellerud BC, Thorgersen EB, Castellheim A, Pharo A, Lindstad J, Tønnessen TI, Brandtzaeg P, Mollnes TE (2009)
A new dynamic porcine model of meningococcal shock
Shock, 32 (3), 302-9
PubMed 19174740

Thorgersen EB, Hellerud BC, Nielsen EW, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Fosse E, Tønnessen TI, Johansen HT, Castellheim A, Mollnes TE (2009)
CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs
FASEB J, 24 (3), 712-22
PubMed 19841036

Publications 2008

Castellheim A, Thorgersen EB, Hellerud BC, Pharo A, Johansen HT, Brosstad F, Gaustad P, Brun H, Fosse E, Tønnessen TI, Nielsen EW, Mollnes TE (2008)
New biomarkers in an acute model of live Escherichia coli-induced sepsis in pigs
Scand J Immunol, 68 (1), 75-84
PubMed 18466195

Waelgaard L, Thorgersen EB, Line PD, Foss A, Mollnes TE, Tønnessen TI (2008)
Microdialysis monitoring of liver grafts by metabolic parameters, cytokine production, and complement activation
Transplantation, 86 (8), 1096-103
PubMed 18946348

Publications 2007

Andersen MH, Mathisen L, Veenstra M, Oyen O, Edwin B, Digernes R, Kvarstein G, Tønnessen TI, Wahl AK, Hanestad BR, Fosse E (2007)
Quality of life after randomization to laparoscopic versus open living donor nephrectomy: long-term follow-up
Transplantation, 84 (1), 64-9
PubMed 17627239

Halvorsen PS, Sokolov A, Cvancarova M, Hol PK, Lundblad R, Tønnessen TI (2007)
Continuous cardiac output during off-pump coronary artery bypass surgery: pulse-contour analyses vs pulmonary artery thermodilution
Br J Anaesth, 99 (4), 484-92
PubMed 17650518

Publications 2006

Andersen MH, Mathisen L, Oyen O, Edwin B, Digernes R, Kvarstein G, Tønnessen TI, Wahl AK, Hanestad BR, Fosse E (2006)
Postoperative pain and convalescence in living kidney donors-laparoscopic versus open donor nephrectomy: a randomized study
Am J Transplant, 6 (6), 1438-43
PubMed 16686768

Halvorsen PS, Espinoza A, Lundblad R, Cvancarova M, Hol PK, Fosse E, Tønnessen TI (2006)
Agreement between PiCCO pulse-contour analysis, pulmonal artery thermodilution and transthoracic thermodilution during off-pump coronary artery by-pass surgery
Acta Anaesthesiol Scand, 50 (9), 1050-7
PubMed 16987335

Waelgaard L, Pharo A, Tønnessen TI, Mollnes TE (2006)
Microdialysis for monitoring inflammation: efficient recovery of cytokines and anaphylotoxins provided optimal catheter pore size and fluid velocity conditions
Scand J Immunol, 64 (3), 345-52
PubMed 16918704

Publications 2005

Mathisen L, Andersen MH, Hol PK, Lingaas PS, Lundblad R, Rein KA, Tønnessen TI, Mørk BE, Svennevig JL, Wahl AK, Hanestad BR, Fosse E (2005)
Patient-reported outcome after randomization to on-pump versus off-pump coronary artery surgery
Ann Thorac Surg, 79 (5), 1584-9
PubMed 15854937

Publications 2004

Kvarstein G, Mirtaheri P, Tønnessen TI (2004)
Detection of ischemia by PCO2 before adenosine triphosphate declines in skeletal muscle
Crit Care Med, 32 (1), 232-7
PubMed 14707584

Mirtaheri P, Grimnes S, Martinsen OG, Tønnessen TI (2004)
A new biomedical sensor for measuring PCO2
Physiol Meas, 25 (2), 421-36
PubMed 15132308

Mirtaheri P, Omtveit T, Klotzbuecher T, Grimnes S, Martinsen OG, Tønnessen TI (2004)
Miniaturization of a biomedical gas sensor
Physiol Meas, 25 (6), 1511-22
PubMed 15712728

Skulstad H, Andersen K, Edvardsen T, Rein KA, Tønnessen TI, Hol PK, Fosse E, Ihlen H (2004)
Detection of ischemia and new insight into left ventricular physiology by strain Doppler and tissue velocity imaging: assessment during coronary bypass operation of the beating heart
J Am Soc Echocardiogr, 17 (12), 1225-33
PubMed 15562259

Publications 2003

Bjørnstad PG, Smevik B, Holmstrøm H, Thaulow E, Hagemo PS, Ihlen H, Bjørnerheim R, Lindberg HL, Seem E, Tønnessen TI, Hustveit O, Fosse E (2003)
[Transcatheter closure of atrial septal defects in the oval fossa]
Tidsskr Nor Laegeforen, 123 (15), 2052-4
PubMed 12934130

Kvarstein G, Barstad M, Mirtaheri P, Tønnessen TI (2003)
Tissue carbon dioxide tension: a putative specific indicator of ischemia in porcine latissimus dorsi flaps
Plast Reconstr Surg, 112 (7), 1825-31
PubMed 14663226

Kvarstein G, Mirtaheri P, Tønnessen TI (2003)
Detection of organ ischemia during hemorrhagic shock
Acta Anaesthesiol Scand, 47 (6), 675-86
PubMed 12803584

Tønnessen TI (2003)
Detection of hypoperfusion: read your patient's hand
Crit Care Med, 31 (9), 2407-8
PubMed 14501978

Publications 2002

Bjørnstad PG, Holmstrøm H, Smevik B, Tønnessen TI, Fosse E (2002)
Transcatheter closure of atrial septal defects in the oval fossa: is the method applicable in small children?
Cardiol Young, 12 (4), 352-6
PubMed 12206558

Rasmussen H, Mirtaheri P, Dirven H, Johnsen H, Kvarstein G, Tønnessen TI, Midtvedt T (2002)
PCO(2) in the large intestine of mice, rats, guinea pigs, and dogs and effects of the dietary substrate
J Appl Physiol (1985), 92 (1), 219-24
PubMed 11744663

Publications 2001

Edwin B, Kazaryan AM, Mala T, Pfeffer PF, Tønnessen TI, Fosse E (2001)
Laparoscopic and open surgery for pheochromocytoma
BMC Surg, 1, 2
PubMed 11580870

Hol PK, Fosse E, Mork BE, Lundblad R, Rein KA, Lingaas PS, Geiran O, Svennevig JL, Tonnessen TI, Nitter-Hauge S, Due-Tonnessen P, Vatne K, Smith HJ (2001)
Graft control by transit time flow measurement and intraoperative angiography in coronary artery bypass surgery
Heart Surg Forum, 4 (3), 254-7; discussion 257-8
PubMed 11673148

Kvarstein G, Tønnessen TI (2001)
[Pain--difficult for both laymen and professionals]
Tidsskr Nor Laegeforen, 121 (22), 2577
PubMed 11668750

Lund C, Lundblad R, Fosse E, Tønnessen TI, Sundet K, Brucher R, Russell D (2001)
Ventricular fibrillation during off-pump coronary artery bypass grafting: transcranial Doppler and clinical findings
Cerebrovasc Dis, 12 (2), 139-41
PubMed 11490108

Publications 2000

Fosse E, Elle OJ, Samset E, Johansen M, Røtnes JS, Tønnessen TI, Edwin B (2000)
[Image guided and robotic treatment--the advance of cybernetics in clinical medicine]
Tidsskr Nor Laegeforen, 120 (1), 65-9
PubMed 10815485

Hol PK, Kvarstein G, Viken O, Smedby O, Tønnessen TI (2000)
MRI-guided celiac plexus block
J Magn Reson Imaging, 12 (4), 562-4
PubMed 11042637

Publications 1999

Rasmussen H, Kvarstein G, Johnsen H, Dirven H, Midtvedt T, Mirtaheri P, Tønnessen TI (1999)
Gas supersaturation in the cecal wall of mice due to bacterial CO2 production
J Appl Physiol (1985), 86 (4), 1311-8
PubMed 10194217

Publications 1998

Barstad RM, Fosse E, Geiran OR, Simonsen S, Vatne K, Andersen K, Tønnessen TI (1998)
Minimally invasive direct coronary artery bypass grafting without cardiopulmonary bypass in combination with intraoperative percutaneous transluminal coronary angioplasty for palliative coronary revascularization in a heart transplant recipient
J Heart Lung Transplant, 17 (6), 629-34
PubMed 9662100

Dishart MK, Schlichtig R, Tonnessen TI, Rozenfeld RA, Simplaceanu E, Williams D, Gayowski TJ (1998)
Mitochondrial redox state as a potential detector of liver dysoxia in vivo
J Appl Physiol (1985), 84 (3), 791-7
PubMed 9480934

Publications 1997

Barstad RM, Fosse E, Vatne K, Andersen K, Tønnessen TI, Svennevig JL, Geiran OR (1997)
Intraoperative angiography in minimally invasive direct coronary artery bypass grafting
Ann Thorac Surg, 64 (6), 1835-9
PubMed 9436590

Bjørnstad PG, Thaulow E, Smevik B, Michelsen SS, Tønnessen TI, Fosse E (1997)
[Catheter treatment of congenital heart defects. Arterial septal defects and open ductus arteriosus]
Tidsskr Nor Laegeforen, 117 (20), 2961-4
PubMed 9340856

Fosse E, Lilleås F, Røtnes JS, Edwin B, Tønnessen TI, Hafsahl G, Laerum F (1997)
[The intervention center at the Rikshospital. Experiences from the first year of activity]
Tidsskr Nor Laegeforen, 117 (19), 2779-83
PubMed 9312869

Kvarstein G, Tønnessen TI (1997)
[CO2 pressure used in the diagnosis of ischemia]
Tidsskr Nor Laegeforen, 117 (29), 4251-5
PubMed 9441471

Tønnessen TI (1997)
Biological basis for PCO2 as a detector of ischemia
Acta Anaesthesiol Scand, 41 (6), 659-69
PubMed 9241323

Publications 1996

Rozenfeld RA, Dishart MK, Tønnessen TI, Schlichtig R (1996)
Methods for detecting local intestinal ischemic anaerobic metabolic acidosis by PCO2
J Appl Physiol (1985), 81 (4), 1834-42
PubMed 8904606

Tønnessen TI, Kvarstein G (1996)
PCO2 electrodes at the surface of the kidney detect ischaemia
Acta Anaesthesiol Scand, 40 (5), 510-9
PubMed 8792878

Publications 1995

Aas AT, Tønnessen TI, Brun A, Salford LG (1995)
Growth inhibition of rat glioma cells in vitro and in vivo by aspirin
J Neurooncol, 24 (2), 171-80
PubMed 7562004

Publications 1991

Ludt J, Tønnessen TI, Sandvig K, Olsnes S (1991)
Evidence for involvement of protein kinase C in regulation of intracellular pH by Cl-/HCO-3 antiport
J Membr Biol, 119 (2), 179-86
PubMed 2046087

Tønnessen TI, Tveter KJ (1991)
Drug treatment of pain in patients with urological cancers
Scand J Urol Nephrol Suppl, 138, 253-64
PubMed 1785017

Publications 1990

Tønnessen TI, Sandvig K, Olsnes S (1990)
Role of Na(+)-H+ and Cl(-)-HCO3- antiports in the regulation of cytosolic pH near neutrality
Am J Physiol, 258 (6 Pt 1), C1117-26
PubMed 2163200

Tønnessen TI, Aas AT, Ludt J, Blomhoff HK, Olsnes S (1990)
Regulation of Na+/H+ and Cl-/HCO3- antiports in Vero cells
J Cell Physiol, 143 (1), 178-87
PubMed 2156872

Publications 1989

Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
Effect of anti-inflammatory analgesic drugs on the regulation of cytosolic pH by anion antiport
J Pharmacol Exp Ther, 248 (3), 1197-206
PubMed 2703970

Tønnessen TI, Aas AT, Sandvig K, Olsnes S (1989)
Inhibition of chloride/bicarbonate antiports in monkey kidney cells (Vero) by non-steroidal anti-inflammatory drugs
Biochem Pharmacol, 38 (20), 3583-91
PubMed 2818647

Publications 1988

Reinertsen KV, Tønnessen TI, Jacobsen J, Sandvig K, Olsnes S (1988)
Role of chloride/bicarbonate antiport in the control of cytosolic pH. Cell-line differences in activity and regulation of antiport
J Biol Chem, 263 (23), 11117-25
PubMed 3403517

Publications 1987

Madshus IH, Tønnessen TI, Olsnes S, Sandvig K (1987)
Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport
J Cell Physiol, 131 (1), 6-13
PubMed 3571337

Olsnes S, Ludt J, Tønnessen TI, Sandvig K (1987)
Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH
J Cell Physiol, 132 (2), 192-202
PubMed 3624315

Olsnes S, Tønnessen TI, Ludt J, Sandvig K (1987)
Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines
Biochemistry, 26 (10), 2778-85
PubMed 3606992

Tønnessen TI, Ludt J, Sandvig K, Olsnes S (1987)
Bicarbonate/chloride antiport in Vero cells: I. Evidence for both sodium-linked and sodium-independent exchange
J Cell Physiol, 132 (2), 183-91
PubMed 3624314

Publications 1986

Olsnes S, Tønnessen TI, Sandvig K (1986)
pH-regulated anion antiport in nucleated mammalian cells
J Cell Biol, 102 (3), 967-71
PubMed 3949885

Sandvig K, Tønnessen TI, Olsnes S (1986)
Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin
Cancer Res, 46 (12 Pt 1), 6418-22
PubMed 3096563

Sandvig K, Tønnessen TI, Sand O, Olsnes S (1986)
Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH
J Biol Chem, 261 (25), 11639-44
PubMed 3745160

van Deurs B, Tønnessen TI, Petersen OW, Sandvig K, Olsnes S (1986)
Routing of internalized ricin and ricin conjugates to the Golgi complex
J Cell Biol, 102 (1), 37-47
PubMed 3001103

Publications 1982

Tönnessen TI, Nyland H, Aarli JA (1982)
Complement factors and acute phase reactants in the Guillain-Barré syndrome
Eur Neurol, 21 (2), 124-8
PubMed 6920298