Research groups
- Molecular Biology of Breast Cancer, headed by Anne-Lise Børresen-Dale
- Cancer genome variation, headed by Vessela N. Kristensen
- Molecular Profiling of GI Cancer, headed by Elin H. Kure
- Tumor initiating cells in breast cancer progression, headed by Therese Sørlie
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| Anne-Lise Børresen-Dale | Vessela N. Kristensen | Elin H. Kure |
Therese Sørlie |
Project groups
- Statistical integrated approaches : Hiroko K. Solvang
- Response and Side Effects of Cancer Therapy : Hege Edvardsen
- Translational studies with a special focus on lung cancer : Åslaug Helland
- Cancer in the respiratory tract : Odd Terje Brustugun
- Genomic and functional analysis of therapeutic targets in breast cancer : Kristine Kleivi Sahlberg
- TP53 and somatic genetics of breast cancer : Anita Langerød
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| Hiroko K. Solvang | Hege Edvardsen | Åslaug Helland |
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| Odd Terje Brustugun | Kristine Kleivi Sahlberg | Anita Langerød |
Our goal is to follow the linear time course of predisposition, initiation, early stages and advanced disease and to dissect the molecular mechanisms triggered at each stage and to follow the multidimentional interactions at various levels in a systems biology approach to be able to better do risk estimation, prognostication and prediction.
To reach these goals we have divided our research into 7 activities:
- Gene environment interaction in breast cancer risk
- Tumor initiation and early diagnosis
- Tumor progression and metastasis
- Prediction of treatment response and targeted therapy
- Integrated approaches
- Functional validation
- Biostatistical challenges and approaches
Contact information:
Department of Genetics, Institute for Cancer Research
The Norwegian Radium Hospital, N-0310 Oslo, Norway
Phone: +47 22 93 56 77, Fax: +47 22 93 44 40, Switchboard: +47 22 93 40 00
Research coordinator: Gry A. Geitvik
Department secretary: Mona Hagen
Jun 14, 2013
International approaches to personalized cancer medicine
Jun 5, 2013
Latest publications
Dept of Genetics
Molecular Profiling of Human Mammary Gland Links Breast Cancer Risk to a p27(+) Cell Population with Progenitor Characteristics
Cell Stem Cell (in press)
PubMed 23770079
Molecular responses to toxicological stressors: Profiling microRNAs in wild Atlantic salmon (Salmo salar) exposed to acidic aluminum-rich water
Aquat Toxicol, 138-139C, 98-104 (in press)
PubMed 23728355
Improving Breast Cancer Survival Analysis through Competition-Based Multidimensional Modeling
PLoS Comput Biol, 9 (5), e1003047
PubMed 23671412













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