Research groups
| Molecular Biology of Breast Cancer | Cancer genome variation |
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| Headed by Group Leader and Professor Anne-Lise Børresen-Dale | Headed by Group Leader and Professor Vessela N. Kristensen |
Project groups
| Tumor initiating cells in breast cancer progression | Molecular signatures of disseminated tumor cells in breast cancer | Statistical integrated approaches | Response and Side Effects of Cancer Therapy | Molecular Profiling of GI Cancer |
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| Therese Sørlie | Lars O. Baumbusch | Hiroko K. Solvang | Hege Edvardsen | Elin H. Kure |
| Translational studies with a special focus on lung cancer | Cancer in the respiratory tract | Genomic and functional analysis of therapeutic targets in breast cancer | TP53 and somatic genetics of breast cancer | |
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| Åslaug Helland | Odd Terje Brustugun |
Kristine Kleivi Sahlberg | Anita Langerød |
Our goal is to follow the linear time course of predisposition, initiation, early stages and advanced disease and to dissect the molecular mechanisms triggered at each stage and to follow the multidimentional interactions at various levels in a systems biology approach to be able to better do risk estimation, prognostication and prediction.
To reach these goals we have divided our research into 7 activities:
- Gene environment interaction in breast cancer risk
- Tumor initiation and early diagnosis
- Tumor progression and metastasis
- Prediction of treatment response and targeted therapy
- Integrated approaches
- Functional validation
- Biostatistical challenges and approaches
Contact information:
Department of Genetics, Institute for Cancer Research
The Norwegian Radium Hospital, N-0310 Oslo, Norway
Phone: +47 22 93 56 77, Fax: +47 22 93 44 40, Switchboard: +47 22 93 40 00
Research coordinator: Gry A. Geitvik
Department secretary: Mona Hagen
Print this page [24036 visits]Christos Samakovlis: The molecular basis of airway maturation in Drosophila
Jan 17, 2012
Latest publications
Dept of Genetics
Genome-wide association analysis identifies three new breast cancer susceptibility loci
Nat Genet (in press)
PubMed 22267197
Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway
Cell, 148 (1-2), 244-58
PubMed 22265415
Allele-specific disparity in breast cancer
BMC Med Genomics, 4 (1), 85 (in press)
PubMed 22188678
