Research groups
- Molecular Biology of Breast Cancer, headed by Anne-Lise Børresen-Dale
- Cancer genome variation, headed by Vessela N. Kristensen
- Molecular Profiling of GI Cancer, headed by Elin H. Kure
- Tumor initiating cells in breast cancer progression, headed by Therese Sørlie
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| Anne-Lise Børresen-Dale | Vessela N. Kristensen | Elin H. Kure |
Therese Sørlie |
Project groups
- Statistical integrated approaches : Hiroko K. Solvang
- Response and Side Effects of Cancer Therapy : Hege Edvardsen
- Translational studies with a special focus on lung cancer : Åslaug Helland
- Cancer in the respiratory tract : Odd Terje Brustugun
- Genomic and functional analysis of therapeutic targets in breast cancer : Kristine Kleivi Sahlberg
- TP53 and somatic genetics of breast cancer : Anita Langerød
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| Hiroko K. Solvang | Hege Edvardsen | Åslaug Helland |
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| Odd Terje Brustugun | Kristine Kleivi Sahlberg | Anita Langerød |
Our goal is to follow the linear time course of predisposition, initiation, early stages and advanced disease and to dissect the molecular mechanisms triggered at each stage and to follow the multidimentional interactions at various levels in a systems biology approach to be able to better do risk estimation, prognostication and prediction.
To reach these goals we have divided our research into 7 activities:
- Gene environment interaction in breast cancer risk
- Tumor initiation and early diagnosis
- Tumor progression and metastasis
- Prediction of treatment response and targeted therapy
- Integrated approaches
- Functional validation
- Biostatistical challenges and approaches
Contact information:
Department of Genetics, Institute for Cancer Research
The Norwegian Radium Hospital, N-0310 Oslo, Norway
Phone: +47 22 93 56 77, Fax: +47 22 93 44 40, Switchboard: +47 22 93 40 00
Research coordinator: Gry A. Geitvik
Department secretary: Mona Hagen
Print this page [27373 visits]Latest publications
Dept of Genetics
Improving Breast Cancer Survival Analysis through Competition-Based Multidimensional Modeling
PLoS Comput Biol, 9 (5), e1003047
PubMed 23671412
De Novo 19p13.2 Microdeletion Encompassing the Insulin Receptor and Resistin Genes in a Patient With Obesity and Learning Disability
Am J Med Genet A, 0 (in press)
PubMed 23637016
SNP in TXNRD2 Associated with Radiation-Induced Fibrosis: A Study of Genetic Variation in Reactive Oxygen Species Metabolism and Signaling
Int J Radiat Oncol Biol Phys (in press)
PubMed 23597419
