Research groups
| Molecular Biology of Breast Cancer | Cancer genome variation |
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| Headed by Group Leader and Professor Anne-Lise Børresen-Dale | Headed by Group Leader and Professor Vessela N. Kristensen |
Project groups
| Molecular portraits of breast cancer: Translating genomics to the clinical practice | Molecular signatures of disseminated tumor cells in breast cancer | Statistical integrated approaches | Response and Side Effects of Cancer Therapy |
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| Therese Sørlie | Lars O. Baumbusch | Hiroko K. Solvang | Hege Edvardsen |
| Molecular Studies of Ovarian Carcinoma | Cancer in the respiratory tract | Breast cancer genomics | Somatic genetics of breast cancer |
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| Åslaug Helland | Odd Terje Brustugun |
Kristine Kleivi | Anita Langerød |
Our goal is to follow the linear time course of predisposition, initiation, early stages and advanced disease and to dissect the molecular mechanisms triggered at each stage and to follow the multidimentional interactions at various levels in a systems biology approach to be able to better do risk estimation, prognostication and prediction.
To reach these goals we have divided our research into 7 activities:
- Gene environment interaction in breast cancer risk
- Tumor initiation and early diagnosis
- Tumor progression and metastasis
- Prediction of treatment response and targeted therapy
- Integrated approaches
- Functional validation
- Biostatistical challenges and approaches
Contact information:
Department of Genetics, Institute for Cancer Research
The Norwegian Radium Hospital, N-0310 Oslo, Norway
Phone: +47 22 93 56 77, Fax: +47 22 93 44 40, Switchboard: +47 22 93 40 00
Research coordinator: Gry A. Geitvik
Department secretary: Mona Hagen
Aug 31, 2010
Oslo, September 20-22, 2010
Aug 30, 2010
Latest publications
Department of Genetics
Expression levels of uridine 5'-diphospho-glucuronosyltransferase genes in breast tissue from healthy women are associated with mammographic density
Breast Cancer Res, 12 (4), R65 (in press)
PubMed 20799965
The MYTHEN detector for X-ray powder diffraction experiments at the Swiss Light Source
J Synchrotron Radiat, 17 (Pt 5), 653-68
PubMed 20724787
Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models
BMC Cancer, 10 (1), 433
PubMed 20716336













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