Welcome to the web pages of Øystein Fodstad's group
Biology of metastasis: functional, diagnostic and therapeutic aspects
Metastatic disease is the principle cause of death of cancer patients, and for most common tumor types good regimes for treating overt metastases are still lacking. Early detection of metastatic tumor cells, development of new treatment strategies, and knowledge about how to prevent cancer metastasis are some of the most challenging tasks in cancer research. Our research activities are spanning from studies of different factors involved in causing loss of growth control in tumorigenic cells, to biological characterization of the metastatic phenotype as well as detection, prognostication and therapy of metastatic disease.
Latest publications
Fodstad's group
Immunotoxin targeting EpCAM effectively inhibits peritoneal tumor growth in experimental models of mucinous peritoneal surface malignancies
Int J Cancer (in press)
PubMed 23494569
Intermittent and continuous imatinib in a human GIST xenograft model carrying KIT exon 17 resistance mutation D816H
Acta Oncol, 52 (4), 776-82
PubMed 23480638
Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer
Breast Cancer Res, 15 (1), R16 (in press)
PubMed 23448424
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