The fight against doping

 
Yvette Dehnes<br>Group leader
Yvette Dehnes
Group leader

The Norwegian Doping Control Laboratory at Aker Hospital is one of 34 WADA (World Anti-Doping Agency)-accredited laboratories around the world. Although the main focus of the Norwegian Doping Control Laboratory is to render analytical service to anti-doping organizations like Antidoping Norway as well as international federations, WADA requires at least 7 % of the total budget to be spent on anti-doping research.The laboratory is engaged in research promoting the development of methodologies in analytical chemistry for the detection of doping agents and prohibited methods, as well as the identification of novel doping trends and pharmacological studies on doping agents and methods. Detection of new drugs (steroids and their metabolites, erythropoiesis stimulating agents), as well as the use of longitudinal profiles of indirect markers for doping (hematological, endocrine), have been the laboratory’s main focus areas.

 

 
 

Research projects

 
  • Synthesis of anabolic steroid metabolites by liver microsomes
  • Determination of peptidic drugs using HRLC-MS
  • Beta2 adrenoreceptor agonists and elite athletes: Blood and urinary concentrations of terbutaline, formoterol, salmeterol and procaterol in asthmatic and non-asthmatic subjects
  • Feasability studies for detection of autologous blood transfusion
  • Longitudinal profiles of biomarkers IGF-1 and PIIINP for detection of GH-misuse
  • Anabolic steroid effects on brain morphology, cognitive functioning, and emotional processing: a follow-up of long-term steroid users
  • Characterization of erythropoietin (EPO) produced in liver, a potential source to atypical EPO profiles in doping samples
 
 
 

Contact information
Yvette Dehnes, Department of Pharmacology, Norwegian Doping Control Laboratory (NLD)
Tel: +47 22894914/48179727, E-mail: yvette@dopinganalyse.no