Radioimmunotherapy of cancer with alpha- and beta-emitting monoclonal antibodies
Radioimmunoconjugates (RICs) are radionuclides conjugated to monoclonal antibodies. The goal of radioimmunotherapy is to target radiation to tumor tissue while limiting the toxicity to normal cells. Our goal is to make a significant contribution in making radioimmunotherapy a new standard cancer treatment.
KEY ACHIEVEMENTS
227Thorium-rituximab targets and inhibits growth of CD20 positive tumors, (Blood, 2007).
GROUP MEMBERS
Principal investigator: Jostein Dahle
PhD-students: Nasir Abbas, Erta Kalanxhi, Helen Heyerdahl and Ada Repetto
Senior Bio Engineer: Camilla Mollatt
Guest scientist: Vanja Hårsaker
Our projects are sponsored by the Norwegian Cancer Society, the Norwegian Research council, the Health Authorities of South Eastern Norway, Innovation Norway, Algeta ASA and Nordic Nanovector AS.
KEY ACHIEVEMENTS
227Thorium-rituximab targets and inhibits growth of CD20 positive tumors, (Blood, 2007).
GROUP MEMBERS
Principal investigator: Jostein Dahle
PhD-students: Nasir Abbas, Erta Kalanxhi, Helen Heyerdahl and Ada Repetto
Senior Bio Engineer: Camilla Mollatt
Guest scientist: Vanja Hårsaker
Our projects are sponsored by the Norwegian Cancer Society, the Norwegian Research council, the Health Authorities of South Eastern Norway, Innovation Norway, Algeta ASA and Nordic Nanovector AS.
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Jan 17, 2012
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Christos Samakovlis: The molecular basis of airway maturation in Drosophila
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Latest PubMed articles
Experimental ?-particle radioimmunotherapy of breast cancer using 227Th-labeled p-benzyl-DOTA-trastuzumab
EJNMMI Res, 1 (1), 18
PubMed 22214432
Toxicity and relative biological effectiveness of alpha emitting radioimmunoconjugates
Curr Radiopharm, 4 (4), 321-8
PubMed 22202154
Genome-wide microarray analysis of human fibroblasts in response to ? radiation and the radiation-induced bystander effect
Radiat Res, 177 (1), 35-43
PubMed 22034846
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