A Norwegian randomized clinical trial shows that it is safe to change from expensive originator medicine to a less expensive biosimilar product. The effect is the same but the costs are reduced more than 50% in Norway. This means that more patients can receive this important treatment. The results of the study are now published in one of the world’s most recognised medical journals, The Lancet (journal impact factor 44.0). The findings have been covered by the Norwegian Broadcasting Corporation (NRK).
Scientists participating in the study affiliated to Oslo University Hospital were Merete Lorentzen (shared first authorship), Knut Lundin and Nils Bolstad.
Three scientists received awards for their outstanding research at a ceremony taking place at Oslo University Hospital May 5th.
The major prize - the "Excellent Researcher Award" - went to professor Kirsten Sandvig.
Johannes Espolin Roksund Hov and Tor Paaske Utheim both received the "Early Career Award".
The prize money - 300.000 and 150.000 NOK respectively - is earmarked for research activities. This prize is distributed anually in order to honour excellent scientific work.
Welcome to the next Oslo University Hospital research seminar entitled "Organ donation for abdominal and thoracic organs".
Time: Monday, May 8th, 2017, at 14:30 – 16:00.
Place: Red Auditorium, Rikshospitalet, Sognsvannsveien 20, Oslo.
Speakers: Pål Dag Line, Arnt Fiane, Stein Foss and Jan E. Brinchmann
The objective of the workshop is to familiarize the participants with the prospective calls in the future EU thematic 2018-2020 health programme: Societal Challenge 1: Health, Demographic Change and Well-being.
After a presentation of the work programme content, resource personnel will be available for discussions to identify the calls that fit the participants' long-term scientific interests.
The workshop will last 2 hours.
It will be arranged
Rikshospitalet: Seminarrom 3 B1.1017, Monday 8th May at 9:00 – 11:00
Radiumhospitalet: Seminarrom 1 FOBY, Monday 8th May at 13:00 – 15:00
Ullevål: Rom 390 at Søsterhjemmet, Tuesday 9th May at 13:00 – 15:00
The Norwegian Cancer Society present research they support regularly, in a popular science form, and they have recently published a feature article on late effects after cancer treatment.
Cecilie Kiserud, head of the National Advisory Unit on Late Effects after Cancer Treatment at the Department of Oncology, has been interviewed about their research activites and new insight into life after cancer, a field that has gained more attention the recent years.
Welcome to the next Oslo University Hospital research seminar entitled "Immunotherapy for Cancer".
Time: Tuesday, April 25th, 2017, at 10:00-15:45.
Place: Store Auditorium, Rikshospitalet, Sognsvannsveien 20, Oslo.
Note that there is a limited number of seats. Please sign up at:
Replication forks must be stabilized in order to avoid DNA breakage and recombination. In a study recently published in Nucleic Acids Research (journal impact factor 9.2), entitled “SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms“, researchers in the Skarstad group show that double strand breaks are generated in the absence of fork-trailing SeqA structures and that cells then have lost the ability to perform direct (RecA-independent) restart of replication forks.
The two first authors are Ida Benedikte Pedersen and Emily Helgesen (photo).
Welcome to the next Oslo University Hospital research seminar entitled "Innovation to Finance Research".
Time: Monday, April 3rd, 2017, at 14:30 – 16:00.
Place: Green Auditorium, Rikshospitalet, Sognsvannsveien 20, Oslo.
Researchers from the NORMENT KG Jebsen Centre for Psychosis Research at OUS and UiO have participated in a large international consortium to develop a novel tool for genetic risk prediction in Alzheimer’s disease. This is based on a long standing collaboration between the statistical genetics team at NORMENT and the University of California San Diego (UCSD) Center for Translational Imaging and Precision Medicine. The scientists are now working to improve the method for mental illness applications.
The results have recently been published in Plos Medicine (journal impact factor 13.6). The study has received widespread attention, including articles in major international newspapers.
The American Association for Cancer Research (AACR) - Women in Cancer Research (WICR) Charlotte Friend Memorial Lectureship was established in 1998 in honour of renowned virologist and discoverer of the Friend virus, Dr. Charlotte Friend. The WICR Friend Lectureship is presented to an outstanding scientist who has made meritorious contributions to the field of cancer research and who has, through leadership or by example, furthered the advancement of women in science.
Anne-Lise Børresen-Dale, professor emerita at the Department of Cancer Genetics at the Institute for Cancer Research, OUH, has been chosen as the 20th Annual Award Recipient. Her award lecture will be held on April 3rd in the Washington Convention Center.
“Centre for Cancer Cell Reprogramming”, affiliated with the Institute of Clinical Medicine at University of Oslo, has been funded by the Research Council of Norway as a new Centre of Excellence.
Jørgen Wesche earned his PhD in Sjur Olsnes's group in 2001, studying intracellular transport and membrane translocation. During his postdoctoral training, spending some time at Institute Curie in Paris, he has changed his focus towards problems with more translational relevance, specializing in live cell imaging, fibroblast growth factor receptor (FGFR) signaling and importance of FGFR in cell migration/invasion. Aberrations in FGFR signaling are found in several types of sarcoma and that´s the main reason way Jørgen started to get interested in sarcoma biology and treatment. He has several exciting ideas on how to further develop his research into more translational/clinical relevance.
Professor Per Ottar Seglen, formerly head of the Proteomics & Mammalian Cell Biology Section at the Institute for Cancer Research, OUH, currently a guest researcher at NCMM, has been awarded the prestigious King Olav V’s prize for Cancer Research 2017.
The award, formally announced by the Norwegian Cancer Society today, is recognized as one of the Norwegian cancer research community’s most respected prizes. Professor Seglen has been awarded the prize in recognition of his ground-breaking research into autophagic-lysosomal protein degradation and its relationship to cancer.
The prize will be officially presented by King Harald V, on behalf of the Cancer Society, at a special ceremony on 6 June 2017. The prize is NOK 1 million.
Welcome to the next Oslo University Hospital research seminar entitled "Health after transplantation".
Time: Monday, March 6th, 2017, at 14:30 – 16:00.
Place: Red Auditorium, Rikshospitalet, Sognsvannsveien 20, Oslo.
Like a fingerprint, the connections of the human brain render us distinct from one another. In a study published in the February 20th issue of Nature Neuroscience (journal impact factor 16.7), entitled "Delayed stabilization and individualization in connectome development are related to psychiatric disorders", researchers at NORMENT reveal that such a unique, fingerprint-like pattern evolves during development and is sensitive to mental health. First and last authors are Tobias Kaufmann and Lars T. Westlye (photo).
The study has already gained attention, and the results have been discussed in articles published in Science Daily and Medical News Today.
Professor Arne Klungland, section head at the Department of Microbiology, will hold a lecture on the subject of embryonic development during a breakfast meeting held by the The Norwegian Biotechnology Advisory Board (Bioteknologirådet).
Klungland is the leader of several research projects aiming at understanding the first few days during embryonic development, and gain insight into the early development of various diseases.
Time: March 1st 8.15-9.30 AM (breakfast from 8.15, lecture starts 8.30)
Place: Håndverkeren, Galleriet (1st floor)
This is a unique seminar with the Olav Thon Foundation's International Research Awardees for Mathematics and Natural Science and Medicine 2017.
The first talk will be held by International Research Prize winner Jan Hoeijmakers from Erasmus University Rotterdam, who is one of the most significant scientists in molecular genetics of our time.
Further talks will be held by Research Awardee Mahmood Amiry-Moghaddam on Parkinson's disease, and by Research Awardees Henrik Zetterberg and Nenad Bogdanovic on Alzheimer research.
Time and place: March 2nd, 2017 12:00 PM - 03:00 PM, Runde Auditorium R-105 at Domus Medica, Gaustad
Deadline for registration: February 23rd
Sports play an important role in our society. Four Norwegian researchers, two from OUS, have published an article in EMBO reports where they discuss problems occurring in the testing of athletes for doping.
The authors (E. Boye and T. Skotland from OUS (photo), J. Nissen-Meyer from UiO and B. Østerud, UiTø) describe how the World Antidoping Agency (WADA) pretends never to make mistakes and is resistant to any form of discussion with other scientists. This attitude creates false positives and athletes are being sanctioned while innocent, with dramatic consequences for the individual. It is argued that both the technological, ethical and legal procedures should be revised and an independent body should monitor the function of WADA.
Welcome to the next Oslo University Hospital research seminar entitled "Early phase drug development: From idea to concept".
Time: Monday, February 6th, 2017, at 14:30 – 16:00.
Place: Blue Auditorium, Rikshospitalet, Sognsvannsveien 20, Oslo.
The article "Targeting of cancer neoantigens with donor-derived T cell receptor repertoires" by Erlend Strønen et al, published in Science in June 2016, is highlighted by an editorial in the "Clinical Implications of Basic Research" section in the Feb 2nd edition of New England Journal of Medicine.
The editorial is entitled "The Antigenicity of the Tumor Cell — Context Matters".
|Previous news articles|
|6th National Conference on Stroke Oslo Kongressenter, February 09-10 2017|
|Theis Tønnessen appointed "Scientist of the Month" by "Helse Sør-Øst" for January 2017|
|Sepsis: New definitions and future research OUH research seminar, Thursday, January 26th|
|Excellent Researcher Award and Early Career Award 2017 Announcement: Nominating outstanding scientists, closing date March 1st:|
|Antimicrobial resistance - how bad is the situation in the world of virus, fungus and mycoplasma? OUH research seminar, Monday, January 16th|
|Findings from Rusten group published in Nature on microenvironmental autophagy draw nationwide attention Updated: honoured with "Preview" article in Developmental Cell|
|Commentary article from Arne Klungland in Nature Methods on epitranscriptome analysis|
|Research funding from South-Eastern Norway Regional Health Authority for 2017|
|Educating future cancer researchers from Ullern high school|
|Novel cancer immunotherapy published in Cancer Research, with cover illustration|
|Oslo University Hospital research seminar: Exercise and Brain Energy Monday, November 21st, 2016, at 14:30 – 16:10|
|Oslo University Hospital research seminar: The World of Immunology Thursday November 17th at 10:00-15:00|
|Oslo University Hospital researchers receive 77.3 mill NOK from the Norwegian Cancer Society Results of Open Call 2016:|
|Human lung macrophages are self-maintained for several years|
|Announcement of research funding from the Norwegian Cancer Society Gathering Friday October 28th 10-12 at UiO:|
|Dag Berild awarded the "Akademikerprisen" for his work on antibiotic resistance|
|50 years anniversary Institute for Surgical Research Thursday 13 October 2016 at 10.15 AM|
|Making therapeutic antibodies from scratch|
|Lina Prasmickaite's work presented in popularised form|
|Medical imaging in cardiac research Oslo University Hospital research seminar Monday October 10th|
|Focus on personalized medicine and the MetAction study|
|Histone marks regulate maternal-to-zygotic transition Paper from Dahl/Klungland published in the Sep 22nd issue of Nature|
|Turning the tide of antimicrobial resistance National kick-off, Tuesday September 13th|
|Marina Vietri interviewed for major Italian research web portal|
|OUH researchers publish groundbreaking computer tools for cell biology research in Nature Methods|
|POLE proofreading domain mutations identify a subset of immunogenic colorectal cancers with excellent prognosis|
|Clinical Cancer Research highlights biomarker paper from Lyng’s group|
|The Norwegian Cancer Genomics Consortium participates in international study of gene variants predisposing for cancer development.|
|Annuncement of research funding from South-East Norway regional health authority for 2017 Call for applications 2017|
|H.M. the King's Gold Medal to Marina Vietri|
|Oslo University Hospital has awarded 6 excellent articles for the second half-year of 2015|
|Atle Bjørnerud "Innovator of the Month" South-Eastern Norway Regional Health Authority brings attention to innovation:|
|Tomas Lindahl, Nobel Prize laureate 2015 Symposium at OUS, Rikshospitalet, 17. June 2016 13:00-15:30|
|The 2016 Excellent Research Awards to Pål Aukrust, Therese Seierstad and Espen Melum Oslo University Hospital honouring outstanding scientific work:|
|Strønen and Olweus publish article in Science on the use of donor immunity to target cancer|
|Håvard Danielsen and Erik Fosse receive Lighthouse project grants from the Norwegian Research Council|
|"Intelligent needle tracking using ultrasound imaging for improved minimally invasive interventions" supported by EU OUS scientists partners in project funded by HORIZON 2020 FAST TRACK TO INNOVATION|
|Discovery of biologically active small molecular compounds Oslo University Hospital research seminar Monday May 9th|
|Mapping somatic mutations in breast cancer whole genomes OUS scientists co-author Nature article:|
|Same, but different? Genetic analysis of five immune mediated diseases reveals molecular taxonomy of chronic inflammation|
|Immunotherapy for Cancer Day of Immunology Conference 2016 April 29|
|New guidelines for "Helse Sør-Øst" and "Kreftforeningen" applications Information meeting, Radiumhospitalet, Friday April 22nd|
|Ståle Nygård – Dept. of Core Facilities Institute seminar April 6th|
|Article published in Science Translational Medicine showing that cyclodextrin may reduce atherosclerosis attracts worldwide attention|
|The Fridtjof Nansen Award for Young Scientists for 2016 to Kyrre Eeg Emblem|
|Theodossiou and Berg funded by the Future and Emerging Technology (FET) program|
|King Olav V's cancer research prize for 2016 to Kjetil Taskén|
|Morgendagens medisin The Norwegian Inflammation Network seminar Wednesday March 16th|
|Microbiome Oslo University Hospital research seminar Monday March 14th|
|Liliane Christ identifies mechanism for regulation of daughter cell separation|
|NoPSC study of PSC gut microbiota published in Gut|
|Olav Thon Foundation's International Prize and Research Awardees 2016 Invitation to seminar March 3rd 12:00|
|Stephen H. Friend Norsk Hydro's Fond guest lecture March 10th|
|Ragnhild A. Lothe and Michael Bretthauer substantially supported by FRIPRO|
|Filming live cancer cells Camilla Raiborg's work presented in popularised form on forskning.no:|
|Elderly patients benefit from an early invasive strategy Heart study results recently published in Lancet attract attention:|
|Lorenz et al. published an extensive study investigating the genomic chaos in osteosarcoma|
|Personalized Cancer Care Symposium, Oslo, May 18-20, 2016|
|Åslaug Helland’s research on lung cancer presented by the Norwegian Cancer Society|
|Innovation projects funded by the Norwegian Cancer Society and Research Council|
|Medical imaging in cancer biology and personalized therapy Oslo University Hospital research seminar January 11th|
|Sandvig received INNO INDIGO grant for work with biodegradable nanoparticles|
|Work from Bjørås' group published in "Cell Report"|
|Research funding from South-Eastern Norway Regional Health Authority for 2016|
|AACR Recognizes Dr. Anne-Lise Børresen-Dale With 2015 Distinguished Lectureship in Breast Cancer Research|
|Erik Boye - an internationally renowned scientist retires|
|Oslo University Hospital has awarded 6 excellent articles for the first half-year of 2015|
|New PhD Andreas Hoff publishes testis cancer fusion genes in Cancer Research|
|Asta Juzeniene - Dept. of Radiation Biology Institute Seminar Wednesday 9th of December at 12:00|
|Findings regarding a novel non-genomic tamoxifen cytotoxic action published in ACS Chemical Biology|
|Tor Espen Thorvaldsen with cover story in Molecular Cancer Research|
|Oslo University Hospital researchers receive 92 mill NOK from the Norwegian Cancer Society|
|Ragnar Mørk legacy prize 2015 to Guro E. Lind Ceremony Friday November 20th|
|The first-in-man Phase I clinical trial of the EpCAM-targeting immunotoxin MOC31PE|
|Research on sonoactivatable nanoparticles funded by EuroNanoMed II ERA-NET program|
|Research on nanoparticle radiosensitizers funded by Euronanomed II ERA-NET program|
|PCI research funded by Euronanomed II ERA-NET program|
|Jørgen Wesche – Dept. of Molecular Cell Biology Institute Seminar Wednesday 4th of November at 12:00|
|New gold-standard for miRNA annotations published in Annual Reviews of Genetics|
|The Wonder of Stem Cells in Eye and Oral Regeneration Oslo University Hospital research seminar October 19th|
|Presenting the Young Academy of Norway|
|Prestigious award from the Research Council of Norway to Harald A. Stenmark Møbius 2015:|
|Review article from Sveen and co-workers on alternative splicing published in Oncogene|
|The Anders Jahre Senior Medical Prize to Ludvig Sollid|
|Award winner Erik Fosse presented in Uniforum The UiO Innovation Prize:|
|Two studies of PARP inhibition in malignant lymphocytes reveal differential phenotypical responses, DNA damage induction and repair during the cell cycle|
|Kaisa Haglund receives the Jahre prize for young medical researchers Recognition of outstanding scientific work:|
|Oslo Cancer Cluster Innovation Park officially opened|
|New English version of "The Research Handbook- from idea to publication" is available|
|Chronicle on personalised cancer medicine in Aftenposten|
|Preparing for the upcoming health calls for Horizon 2020 Training course August 25:|
|Novel method reveals new knowledge about G1-phase|
|H.M. The Kings Gold Medal to Sigrid Bratlie Thoresen|
|Llorente and coworkers report promising prostate cancer biomarkers in urinary exosomes|
|Microscopy infrastructure funded by the Norwegian Research Council|
|Innovation prize to Erik Fosse|
|Cover article on personalized cancer medicine and big data in META|
|Paper from OUS/CCB researchers dedicated commentary articles in both Nature and Science|
|What is the cost of a cancer patient's life? OUS research blog June 16th:|
|Annuncement of research funding from South-East Norway regional health authority for 2016 Call for applications 2016|