Publications
Publications published since 1996 or in press from OUS - Department of Cell Biology
147 publications found
Publications 2013
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Regulating DNA replication in bacteria
Cold Spring Harb Perspect Biol, 5 (4), a012922
PubMed 23471435 -
Single transmembrane peptide DinQ modulates membrane-dependent activities
PLoS Genet, 9 (2), e1003260
PubMed 23408903
Publications 2012
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Hpz1 modulates the G1-S transition in fission yeast
PLoS One, 7 (9), e44539
PubMed 22970243 -
Induction of a G1-S checkpoint in fission yeast
Proc Natl Acad Sci U S A, 109 (25), 9911-6
PubMed 22665798 -
Depletion of acidic phospholipids influences chromosomal replication in Escherichia coli
Microbiologyopen, 1 (4), 450-66
PubMed 23233230 -
Guidelines for the use and interpretation of assays for monitoring autophagy
Autophagy, 8 (4), 445-544
PubMed 22966490 -
An easy-to-use simulation program demonstrates variations in bacterial cell cycle parameters depending on medium and temperature
PLoS One, 7 (2), e30981
PubMed 22348034 -
Replication fork movement and methylation govern SeqA binding to the Escherichia coli chromosome
Nucleic Acids Res, 40 (12), 5465-76
PubMed 22373925
Publications 2011
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Seeing is believing: the impact of electron microscopy on autophagy research
Autophagy, 7 (9), 935-56
PubMed 21566462 -
Hydrophilic interaction chromatography of nucleoside triphosphates with temperature as a separation parameter
J Chromatogr A, 1218 (35), 5981-6
PubMed 21315360 -
The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication
Mol Microbiol, 79 (2), 433-46
PubMed 21219462 -
Cell-cycle analysis of fission yeast cells by flow cytometry
PLoS One, 6 (2), e17175
PubMed 21386895 -
Replication patterns and organization of replication forks in Vibrio cholerae
Microbiology, 157 (Pt 3), 695-708
PubMed 21163839 -
Autophagic activity measured in whole rat hepatocytes as the accumulation of a novel BHMT fragment (p10), generated in amphisomes by the asparaginyl proteinase, legumain
Autophagy, 7 (9), 1011-27
PubMed 21610319
Publications 2010
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A novel DNA gyrase inhibitor rescues Escherichia coli dnaAcos mutant cells from lethal hyperinitiation
J Antimicrob Chemother, 65 (5), 924-30
PubMed 20228083 -
The Norse god of autophagy. Interviewed by Daniel J Klionsky
Autophagy, 6 (8), 1017-31
PubMed 20814236 -
Purification of autophagosomes from rat hepatocytes
Autophagy, 6 (4), 542-7
PubMed 20505360 -
ChIP on Chip: surprising results are often artifacts
BMC Genomics, 11, 414
PubMed 20602746
Publications 2009
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Escherichia coli DnaA forms helical structures along the longitudinal cell axis distinct from MreB filaments
Mol Microbiol, 72 (3), 645-57
PubMed 19400775 -
In DNA replication, the early bird catches the worm
Cell, 136 (5), 812-4
PubMed 19269359 -
Checkpoint regulation of DNA replication
Methods Mol Biol, 521, 55-70
PubMed 19563101 -
DnaA protein interacts with RNA polymerase and partially protects it from the effect of rifampicin
Mol Microbiol, 71 (4), 1018-30
PubMed 19170875 -
Growth rate dependent numbers of SeqA structures organize the multiple replication forks in rapidly growing Escherichia coli
Genes Cells, 14 (5), 643-57
PubMed 19371375 -
A reduction in ribonucleotide reductase activity slows down the chromosome replication fork but does not change its localization
PLoS One, 4 (10), e7617
PubMed 19898675 -
Temporary fatigue and altered extracellular matrix in skeletal muscle during progression of heart failure in rats
Am J Physiol Regul Integr Comp Physiol, 297 (1), R26-33
PubMed 19339678 -
Sequestration assays for mammalian autophagy
Methods Enzymol, 452, 63-83
PubMed 19200876 -
Global transcriptional response after exposure of fission yeast cells to ultraviolet light
BMC Cell Biol, 10, 87
PubMed 20015352 -
The right half of the Escherichia coli replication origin is not essential for viability, but facilitates multi-forked replication
Mol Microbiol, 74 (2), 467-79
PubMed 19737351 -
The Escherichia coli ibpA thermometer is comprised of stable and unstable structural elements
RNA Biol, 6 (4), 455-63
PubMed 19535917 -
The Escherichia coli SeqA protein
Plasmid, 61 (3), 141-50
PubMed 19254745 -
BayesPI - a new model to study protein-DNA interactions: a case study of condition-specific protein binding parameters for Yeast transcription factors
BMC Bioinformatics, 10, 345
PubMed 19857274 -
Phosphorylated and non-phosphorylated forms of catechol O-methyltransferase in rat liver, brain and other tissues
Biochem J, 417 (2), 535-45
PubMed 18831714
Publications 2008
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The initiator protein DnaA contributes to keeping new origins inactivated by promoting the presence of hemimethylated DNA
J Mol Biol, 384 (5), 1076-85
PubMed 18835566 -
Rapid regulation of protein activity in fission yeast
BMC Cell Biol, 9, 23
PubMed 18457584 -
A robust screen for novel antibiotics: specific knockout of the initiator of bacterial DNA replication
FEMS Microbiol Lett, 281 (2), 210-4
PubMed 18312360 -
A tribute to Arthur Kornberg 1918-2007
Nat Struct Mol Biol, 15 (1), 2-17
PubMed 18176549 -
The multiple facets of the intra-S checkpoint
Cell Cycle, 7 (15), 2315-20
PubMed 18677104 -
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Autophagy, 4 (2), 151-75
PubMed 18188003 -
Does bafilomycin A1 block the fusion of autophagosomes with lysosomes?
Autophagy, 4 (7), 849-950
PubMed 18758232 -
The G1-S checkpoint in fission yeast is not a general DNA damage checkpoint
J Cell Sci, 121 (Pt 24), 4047-54
PubMed 19033384
Publications 2007
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Organization of sister origins and replisomes during multifork DNA replication in Escherichia coli
EMBO J, 26 (21), 4514-22
PubMed 17914458 -
The Gcn2 kinase as a cell cycle regulator
Cell Cycle, 6 (22), 2768-72
PubMed 17986863 -
How shall I eat thee?
Autophagy, 3 (5), 413-6
PubMed 17568180 -
Methods for monitoring autophagy from yeast to human
Autophagy, 3 (3), 181-206
PubMed 17224625 -
Functional taxonomy of bacterial hyperstructures
Microbiol Mol Biol Rev, 71 (1), 230-53
PubMed 17347523 -
Toward a hyperstructure taxonomy
Annu Rev Microbiol, 61, 309-29
PubMed 17896876 -
A novel checkpoint mechanism regulating the G1/S transition
Genes Dev, 21 (6), 649-54
PubMed 17369398 -
Proteomic analysis of membrane-associated proteins from rat liver autophagosomes
Autophagy, 3 (4), 300-22
PubMed 17377489
Publications 2006
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DisA, a busy bee that monitors chromosome integrity
Cell, 125 (4), 641-3
PubMed 16713555 -
A novel regulatory mechanism couples deoxyribonucleotide synthesis and DNA replication in Escherichia coli
EMBO J, 25 (5), 1137-47
PubMed 16482221 -
DNA damage induces Cdt1 proteolysis in fission yeast through a pathway dependent on Cdt2 and Ddb1
EMBO Rep, 7 (11), 1134-9
PubMed 17039252 -
Induction of apoptosis by hexaminolevulinate-mediated photodynamic therapy in human colon carcinoma cell line 320DM
J Environ Pathol Toxicol Oncol, 25 (1-2), 159-71
PubMed 16566715
Publications 2005
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An oriC-like distribution of GATC sites mediates full sequestration of non-origin sequences in Escherichia coli
J Mol Biol, 350 (1), 7-11
PubMed 15922360 -
The Escherichia coli baby cell column: a novel cell synchronization method provides new insight into the bacterial cell cycle
Mol Microbiol, 57 (2), 380-91
PubMed 15978072 -
Pancreatic trypsin activates human promatrix metalloproteinase-2
J Mol Biol, 350 (4), 682-98
PubMed 15950241 -
Deletion of the datA site does not affect once-per-cell-cycle timing but induces rifampin-resistant replication
J Bacteriol, 187 (12), 3913-20
PubMed 15939703 -
Specific N-terminal interactions of the Escherichia coli SeqA protein are required to form multimers that restrain negative supercoils and form foci
Genes Cells, 10 (11), 1039-49
PubMed 16236133 -
Stimulation of hepatocytic AMP-activated protein kinase by okadaic acid and other autophagy-suppressive toxins
Biochem J, 386 (Pt 2), 237-44
PubMed 15461583 -
Comigration of two autophagosome-associated dehydrogenases on two-dimensional polyacrylamide gels
Autophagy, 1 (3), 157-62
PubMed 16874067
Publications 2004
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Re-replication from non-sequesterable origins generates three-nucleoid cells which divide asymmetrically
Mol Microbiol, 51 (6), 1589-600
PubMed 15009887 -
Cloning, pharmacological characterisation and tissue distribution of a novel 5-HT4 receptor splice variant, 5-HT4(i)
Naunyn Schmiedebergs Arch Pharmacol, 369 (6), 616-28
PubMed 15118808 -
Positive supercoiling is generated in the presence of Escherichia coli SeqA protein
Mol Microbiol, 54 (1), 123-31
PubMed 15458410 -
Replication fork and SeqA focus distributions in Escherichia coli suggest a replication hyperstructure dependent on nucleotide metabolism
Mol Microbiol, 52 (6), 1597-612
PubMed 15186411 -
Toxin-induced tail phosphorylation of hepatocellular S6 kinase: evidence for a dual involvement of the AMP-activated protein kinase in S6 kinase regulation
Toxicol Sci, 82 (2), 628-37
PubMed 15342961 -
Germinating fission yeast spores delay in G1 in response to UV irradiation
BMC Cell Biol, 5 (1), 40
PubMed 15498101 -
Genetic instability of heterozygous, hybrid, natural wine yeasts
Appl Environ Microbiol, 70 (8), 4686-91
PubMed 15294803 -
Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway
Dev Cell, 7 (2), 179-92
PubMed 15296715
Publications 2003
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Excess SeqA prolongs sequestration of oriC and delays nucleoid segregation and cell division
EMBO J, 22 (2), 315-23
PubMed 12514137 -
Coupling the cell cycle to cell growth
EMBO Rep, 4 (8), 757-60
PubMed 12897798 -
Controlled initiation of chromosomal replication in Escherichia coli requires functional Hda protein
J Bacteriol, 185 (10), 3244-8
PubMed 12730188 -
Lack of SeqA focus formation, specific DNA binding and proper protein multimerization in the Escherichia coli sequestration mutant seqA2
Mol Microbiol, 47 (3), 619-32
PubMed 12535065 -
Lack of inverse dose-rate effect and binding of the retinoblastoma gene product in the nucleus of human cancer T-47D cells arrested in G2 by ionizing radiation
Int J Radiat Biol, 79 (6), 413-22
PubMed 12963543 -
SeqA protein stimulates the relaxing and decatenating activities of topoisomerase IV
J Biol Chem, 278 (49), 48779-85
PubMed 14512422 -
DpiA binding to the replication origin of Escherichia coli plasmids and chromosomes destabilizes plasmid inheritance and induces the bacterial SOS response
J Bacteriol, 185 (20), 6025-31
PubMed 14526013 -
Titration of the Escherichia coli DnaA protein to excess datA sites causes destabilization of replication forks, delayed replication initiation and delayed cell division
Mol Microbiol, 50 (1), 349-62
PubMed 14507385 -
Okadaic acid-induced, naringin-sensitive phosphorylation of glycine N-methyltransferase in isolated rat hepatocytes
Biochem J, 373 (Pt 2), 505-13
PubMed 12697024 -
Intra-G1 arrest in response to UV irradiation in fission yeast
Proc Natl Acad Sci U S A, 100 (19), 10758-63
PubMed 12960401 -
Circles in the sand
EMBO Rep, 4 (7), 661-5
PubMed 12835752 -
Stable co-existence of separate replicons in Escherichia coli is dependent on once-per-cell-cycle initiation
EMBO J, 22 (1), 140-50
PubMed 12505992 -
Degradation of mutant initiator protein DnaA204 by proteases ClpP, ClpQ and Lon is prevented when DNA is SeqA-free
Biochem J, 370 (Pt 3), 867-71
PubMed 12479794
Publications 2002
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Naringin-sensitive phosphorylation of plectin, a cytoskeletal cross-linking protein, in isolated rat hepatocytes
J Biol Chem, 277 (38), 34826-35
PubMed 12095991 -
A novel chk1-dependent G1/M checkpoint in fission yeast
J Cell Sci, 115 (Pt 18), 3609-18
PubMed 12186947
Publications 2001
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Effects of the diarrhetic shellfish toxin, okadaic acid, on cytoskeletal elements, viability and functionality of rat liver and intestinal cells
Toxicon, 39 (2-3), 349-62
PubMed 10978754 -
Defective initiation in an Escherichia coli dnaA(Cs,Sx) mutant
Biochimie, 83 (1), 25-32
PubMed 11254971 -
[The 2001 Nobel Prize in Physiology or Medicine]
Tidsskr Nor Laegeforen, 121 (30), 3500
PubMed 11808003 -
Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuole
J Cell Biol, 153 (2), 381-96
PubMed 11309418 -
Cell cycle progression and radiation survival following prolonged hypoxia and re-oxygenation
Int J Radiat Biol, 77 (3), 319-28
PubMed 11258846 -
Regulation of chromosomal replication by DnaA protein availability in Escherichia coli: effects of the datA region
Biochim Biophys Acta, 1521 (1-3), 73-80
PubMed 11690638 -
Effects of inhibitors of the vacuolar proton pump on hepatic heterophagy and autophagy
Biochim Biophys Acta, 1510 (1-2), 243-57
PubMed 11342162 -
The Escherichia coli SeqA protein binds specifically to two sites in fully and hemimethylated oriC and has the capacity to inhibit DNA replication and affect chromosome topology
Biochimie, 83 (1), 49-51
PubMed 11254974 -
SeqA, the Escherichia coli origin sequestration protein, is also a specific transcription factor
Mol Microbiol, 40 (6), 1371-9
PubMed 11442835 -
SeqA, the Escherichia coli origin sequestration protein, is also a specific transcription factor
Mol. Microbiol., 40 (6), 1371-1379 -
GSA11 encodes a unique 208-kDa protein required for pexophagy and autophagy in Pichia pastoris
J Biol Chem, 276 (45), 42422-35
PubMed 11533052 -
The sequence requirements for a functional Escherichia coli replication origin are different for the chromosome and a minichromosome
Mol Microbiol, 40 (2), 498-507
PubMed 11309131 -
Mutations in DnaA protein suppress the growth arrest of acidic phospholipid-deficient Escherichia coli cells
EMBO J, 20 (5), 1164-72
PubMed 11230139
Publications 2000
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Mapping of a chromosome replication origin in an archaeon
Trends Microbiol, 8 (12), 535-7
PubMed 11115744 -
Prevention of toxin-induced cytoskeletal disruption and apoptotic liver cell death by the grapefruit flavonoid, naringin
Cell Death Differ, 7 (8), 739-46
PubMed 10918448 -
Limiting DNA replication to once and only once
EMBO Rep, 1 (6), 479-83
PubMed 11263490 -
Hypoxia, normoxia and hyperoxia--terminology for medical in vitro cell biology
Acta Oncol, 39 (2), 247-8
PubMed 10859022 -
Ultrastructural characterization of the delimiting membranes of isolated autophagosomes and amphisomes by freeze-fracture electron microscopy
Eur J Cell Biol, 79 (12), 871-82
PubMed 11152279 -
Autophagosome-associated variant isoforms of cytosolic enzymes
Biochem J, 352 Pt 3, 773-81
PubMed 11104685 -
A fission yeast general translation factor reveals links between protein synthesis and cell cycle controls
J Cell Sci, 113 ( Pt 8), 1447-58
PubMed 10725227 -
The Escherichia coli SeqA protein binds specifically and co-operatively to two sites in hemimethylated and fully methylated oriC
Mol Microbiol, 36 (6), 1319-26
PubMed 10931282 -
The Escherichia coli SeqA protein destabilizes mutant DnaA204 protein
Mol Microbiol, 37 (3), 629-38
PubMed 10931356 -
The eclipse period of Escherichia coli
EMBO J, 19 (22), 6240-8
PubMed 11080169
Publications 1999
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Regulation of the start of DNA replication in Schizosaccharomyces pombe
J Cell Sci, 112 ( Pt 6), 939-46
PubMed 10036243 -
Measurement of dose rate at the interface of cell culture medium and glass dishes by means of ESR dosimetry using thin films of alanine
Radiat Res, 152 (1), 76-82
PubMed 10381844 -
Inverse dose-rate effect due to pre-mitotic accumulation during continuous low dose-rate irradiation of cervix carcinoma cells
Int J Radiat Biol, 75 (6), 699-707
PubMed 10404999 -
Eleven novel sep genes of Schizosaccharomyces pombe required for efficient cell separation and sexual differentiation
Yeast, 15 (8), 669-86
PubMed 10392445 -
Spermatocytic seminoma as compared to classical seminoma: an immunohistochemical and DNA flow cytometric study
APMIS, 107 (3), 297-302
PubMed 10223302 -
The gene for 2-phosphoglycolate phosphatase (gph) in Escherichia coli is located in the same operon as dam and at least five other diverse genes
Biochim Biophys Acta, 1472 (1-2), 376-84
PubMed 10572959 -
Distribution of minichromosomes in individual Escherichia coli cells: implications for replication control
EMBO J, 18 (6), 1712-21
PubMed 10075940 -
Escherichia coli SeqA protein affects DNA topology and inhibits open complex formation at oriC
EMBO J, 18 (17), 4882-8
PubMed 10469666 -
Glucose-induced autophagy of peroxisomes in Pichia pastoris requires a unique E1-like protein
Mol Biol Cell, 10 (5), 1353-66
PubMed 10233149
Publications 1998
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The retinoblastoma protein-associated cell cycle arrest in S-phase under moderate hypoxia is disrupted in cells expressing HPV18 E7 oncoprotein
Br J Cancer, 77 (6), 862-72
PubMed 9528826 -
Are minichromosomes valid model systems for DNA replication control? Lessons learned from Escherichia coli
Mol Microbiol, 29 (3), 671-5
PubMed 9723907 -
Isolation and characterization of rat liver amphisomes. Evidence for fusion of autophagosomes with both early and late endosomes
J Biol Chem, 273 (34), 21883-92
PubMed 9705327 -
Flow cytometry of bacterial cells: comparison between different flow cytometers and different DNA stains
Cytometry, 31 (1), 29-36
PubMed 9450522 -
Coordination of initiation of nuclear division and initiation of cell division in Schizosaccharomyces pombe: genetic interactions of mutations
J Bacteriol, 180 (4), 892-900
PubMed 9473044 -
Blood transfusions downregulate hematopoiesis and subsequently downregulate the immune response
Transfusion, 38 (11-12), 1104-14
PubMed 9838944 -
Survival of synchronized human NHIK 3025 cells irradiated aerobically following a prolonged treatment with extremely hypoxic conditions
Int J Radiat Biol, 74 (4), 491-500
PubMed 9798960 -
Inhibition of hepatocytic autophagy by adenosine, adenosine analogs and AMP
Biol Chem, 379 (11), 1341-7
PubMed 9865607 -
Impaired growth of an Escherichia coli rpe mutant lacking ribulose-5-phosphate epimerase activity
Biochim Biophys Acta, 1381 (3), 319-30
PubMed 9729441 -
Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism
J Neurosci, 18 (18), 7296-305
PubMed 9736650 -
Inhibition of hepatocytic autophagy by adenosine, aminoimidazole-4-carboxamide riboside, and N6-mercaptopurine riboside. Evidence for involvement of amp-activated protein kinase
J Biol Chem, 273 (37), 23758-63
PubMed 9726984 -
Citation rates and journal impact factors are not suitable for evaluation of research
Acta Orthop Scand, 69 (3), 224-9
PubMed 9703393 -
Purification and characterization of autophagosomes from rat hepatocytes
Biochem J, 335 ( Pt 2), 217-24
PubMed 9761717 -
Effects of purified SeqA protein on oriC-dependent DNA replication in vitro
EMBO J, 17 (14), 4158-65
PubMed 9670030
Publications 1997
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The absence of effect of gid or mioC transcription on the initiation of chromosomal replication in Escherichia coli
Proc Natl Acad Sci U S A, 94 (23), 12497-502
PubMed 9356478 -
Measurement of nuclear DNA content in fission yeast by flow cytometry
Yeast, 13 (14), 1329-35
PubMed 9392077 -
An approach to identify functional homologues and suppressors of genes in fission yeast
Curr Genet, 32 (1), 27-31
PubMed 9309167 -
Immune response after syngeneic and allogeneic blood cell transplantation
Transplant Proc, 29 (4), 2181-2
PubMed 9193579 -
A comparison of different modes for the detection of p53 protein accumulation. A study of bladder cancer
Pathol Res Pract, 193 (7), 471-8
PubMed 9342752 -
Why the impact factor of journals should not be used for evaluating research
BMJ, 314 (7079), 498-502
PubMed 9056804 -
DNA ploidy and autophagic protein degradation as determinants of hepatocellular growth and survival
Cell Biol Toxicol, 13 (4-5), 301-15
PubMed 9298250 -
Citations and journal impact factors: questionable indicators of research quality
Allergy, 52 (11), 1050-6
PubMed 9404555 -
Uncoupling of the order of the S and M phases: effects of staurosporine on human cell cycle kinases
Cell Prolif, 30 (5), 197-218
PubMed 9420612 -
Regulation of autophagy by protein phosphorylation
BIOM HLTH R, 13, 357-366 -
A novel method for the study of autophagy: destruction of hepatocytic lysosomes, but not autophagosomes, by the photosensitizing porphyrin tetra(4-sulphonatophenyl)porphine
Biochem J, 321 ( Pt 1), 217-25
PubMed 9003422 -
Differences between fluid-phase endocytosis (pinocytosis) and receptor-mediated endocytosis in isolated rat hepatocytes
Eur J Cell Biol, 73 (1), 28-39
PubMed 9174669
Publications 1996
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Coordinating DNA replication initiation with cell growth: differential roles for DnaA and SeqA proteins
Proc Natl Acad Sci U S A, 93 (22), 12206-11
PubMed 8901558 -
The ORC1 homolog orp1 in fission yeast plays a key role in regulating onset of S phase
Genes Dev, 10 (20), 2644-54
PubMed 8895665 -
Role of cAMP in the regulation of hepatocytic autophagy
Eur J Biochem, 236 (1), 163-70
PubMed 8617261 -
Transcriptional activation of promoters of the superoxide and multiple antibiotic resistance regulons by Rob, a binding protein of the Escherichia coli origin of chromosomal replication
J Bacteriol, 178 (9), 2507-13
PubMed 8626315 -
Use of multiple PCR primer sets for optimal detection of human papillomavirus
J Clin Microbiol, 34 (9), 2095-100
PubMed 8862564 -
Structural aspects of autophagy
Adv Exp Med Biol, 389, 103-11
PubMed 8860999 -
The Escherichia coli Fis protein prevents initiation of DNA replication from oriC in vitro
Nucleic Acids Res, 24 (18), 3527-32
PubMed 8836178




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