Tone Aase Fykerud graduated

We congratulate Tone Aase Fykerud on being awarded the degree of Master of Science by the University of Oslo. She defended her Master thesis on June 23. In her Master project, Tone investigated the molecular mechanisms involved in endocytosis and degradation of the gap junction protein connexin43, with emphasis on the role of ubiquitin. Edward Leithe has acted as a supervisor on the project. Tone started her Master project in October 2008, and is now working as a research associate in our department.

Forskning om nerveskjedesvulster omtalt på forskningsrådets hjemmeside

"Strategisk satsning på kreftforskning (KREFTSATSING)"

Link to PDF.

Master students Marianne Guriby and Deeqa Ali finished their master's degrees in February and March 2010, respectively.

Translational research on colorectal cancer within Oslo University hospital featured in Dagbladet newspaper

A colorectal cancer biomarker discovery project, lead by Professor Ragnhild A. Lothe, was presented on the front page of Dagbladet, May 1st, 2010.

Link to PDF.

Molecular Genetics group publishes in Journal of Clinical Oncology

From left: H.R. Brekke, F. Ribeiro and M. Kolberg.

The "Molecular Genetics group" at the Department of Cancer Prevention and the Centre for Cancer Biomedicine, headed by Ragnhild A. Lothe, has recently published a translational research paper in the highly rated Journal of Clinical Oncology (journal impact factor 17.2). The article - entitled "Genomic Changes in Chromosomes 10, 16, and X in Malignant Peripheral Nerve Sheath Tumors Identify a High-Risk Patient Group" is published in the "Translational oncology" section.
The first three authors are PhD candidate Helge R. Brekke (1st author), Dr. Franclim Ribeiro and Dr. Matthias Kolberg.

MSc degree to Anne Cathrine Bakken

On December 21st, Anne Cathrine Bakken defended her master thesis "Exon-specific biomarkers in cancer: Experimental validation of exon microarray data from colorectal and testicular cancers". Anne Cathrine was successful in validating several novel RNA variants which are specific to cancer. Anne Cathrine is continuing the work as a research associate at the Genome biology group. The master project was supervised by Rolf Skotheim and Ragnhild A Lothe.

Dr. Ragnar Mørk legacy prize 2009 to Rolf I. Skotheim

R.I. Skotheim

The Ragnar Mørk's Leagcy award for 2009 went to Rolf Skotheim, working at the Department of Cancer Prevention at the Institute for Cancer Research. This award is distributed annually to a scientist who has achieved important results. Skotheim is involved in research where DNA and RNA from various cancers types are analysed by integrated computational and laboratory based approaches.
The ceremony took place on Friday 20th of November in Seminar room 1 in the New Research Building at Montebello. Skotheim gave a lecture about his research activities that earned him the award.

Novel regulatory mechanism for intercellular communication identified

Edward Leithe

A study from Edgar Rivedal’s group at the Department of Cancer Prevention provides new insights into the molecular basis underlying the regulation of intercellular communication via gap junctions. The study is published in the November issue of Journal of Cell Science and is co-authored by Edward Leithe, Ane Kjenseth, Solveig Sirnes, Harald Stenmark, Andreas Brech and Edgar Rivedal.

Disputation and trial lecture - Terje Cruickshank Ahlquist

Cand.scient. Terje Cruickshank Ahlquist from Ragnhild A. Lothe's group at the Department of Cancer Prevention defended his PhD thesis entitled "Novel genetic and epigenetic alterations in colorectal tumors and their potential as biomarkers" on Wednesday May 13th.

His trial lecture - on the subject "Globale undersøkelser av genomforandringer i human cancer" was held the day before - on Tuesday May 12th.

Both lectures are available on web-TV:
Click here for PhD Thesis Presentation

Click here for Trial Lecture

Stine Danielsen awarded poster prize at the 30th Scandinavian Sarcoma Group Meeting

Stine A. Danielsen, PhD student in Ragnhild A. Lothe's group at the Department of Cancer Prevention, was awarded first prize for best poster at the Scandinavian Sarcoma Group (SSG) 30th Jubilee Meeting held at Hotel Opera in Oslo, May 6-8.

Her poster "Methylation of RASSF1A - a Prognostic Biomarker in NF1-Patients with Malignant Peripheral Nerve Sheath Tumors" was based on recent results obtained from a close collaboration with the three cancer clinics at the Norwegian Radium Hospital, Oslo, Lund University Hospital, Sweden, and the University Hospital of Groningen, the Netherlands.

Previous news

New microarray design for detection of fusion genes

Mutations in the Neurofibromin gene, an inhibitor of KRAS Jan 19, 2009

Ahlquist and colleagues identify time of occurrence of specific methylation events in colorectal development. Jan 2, 2009

Marthe Eken graduated Jan 10, 2009

Skotheim - First runner up to Idea Prize 2008 Jan 10, 2009

Young Investigator Award to Rolf Skotheim Jan 10, 2009

Congratulations to Jarle Bruun Jan 10, 2009

Invited speaker at Biomarker Discovery Conference Jan 10, 2009

”Signaling in colorectal cancer”. Two recent papers by PhD students Stine A. Danielsen and Terje Ahlquist and colleagues Sep 17, 2008

On the road again Sep 15, 2008

Novel effects of chemical carcinogens on intercellular communication identified Sep 5, 2008