Department of Molecular Oncology


Department head: Ragnhild A. Lothe, Professor
Department administrative consultants: Mona Hagen and Linda Uv Mjøen
Lab manager: Guro E. Lind

Research groups:

GeneticsGenome BiologyEpigenetics

Ragnhild A. LotheRolf I. SkotheimGuro E. Lind

Project group:

Cell signalling

Edward Leithe


Centre for Cancer Biomedicine  

Centre for Cancer Biomedicine

A Norwegian Centre of Excellence funded by the Research Council of Norway.


The K.G. Jebsen Colorectal Cancer Research Centre.



Norwegian Cancer Genomics Consortium


Latest News


Group leader Guro E. Lind appointed leader of the newly established Young Academy of Norway


20 young scientists have been selected from 160 applicants to become the founding members of the Young Academy of Norway. Read more at the YA web site and by following the links below.

From Forskerforum:
Overveldende respons for ungt akademi

From Uniforum:
Norge får akademi for unge forskere

From The Norwegian Academy of Science and Letters:
Akademiet for yngre forskere etableres

Akademiet for yngre forskere etableres (including blog)


Review article in Oncogene on alternative splicing in cancer


Dr. Anita Sveen and co-workers recently published a review article about alternative splicing in cancer in the journal Oncogene. In this article, an overview of known aberrant splicing events in cancer-critical genes and their potential as cancer biomarkers is given. The article also discusses cancer-associated patterns of splicing on a genome-wide scale. Furthermore, the genes encoding splicing factors are found to be enriched for cancer-critical somatic mutations and to have dysregulated expression patterns. Several novel cancer-critical splicing factors are proposed. Sveen has previously investigated the biomarker potential of aberrant splicing events in cancer (Sveen et al., Int J Cancer 2012;131:1479-85) and identified transcriptome instability, TIN, in colorectal cancer as a splicing-related molecular feature that is associated with splicing factor gene expression levels and poor patient survival (Sveen et al., Genome Med 2011;3:32 and BMC Genomics 2014;15:672). Sveen is currently a post doc in the Lothe group, working with genomics of colorectal cancer in a translational research perspective.

Link to article:

Link to the Genetics Group in the Department of  Molecular Oncology:

Link to the K.G. Jebsen Colorectal Cancer Research Centre:


Contact information

Department of Molecular Oncology, Institute for Cancer Research
Oslo University Hospital HE - Norwegian Radium Hospital
Mail address: P. O. Box 4953 Nydalen, NO-0424 Oslo, Norway
Street address: Norwegian Radium Hospital, Montebello
Phone: +47 2278 1728, Switchboard: +47 2293 4000, Fax: +47 2278 1745