Welcome to the web pages of Kristian Berg's group
Photochemical internalisation (PCI) is a novel technology for improving the transfer of macromolecules into the cytosol of cells. This is executed through photochemical targeting of endocytic vesicles, leading to release of the contents of these vesicles into the cytosol. The group’s main focus is to develop PCI for therapeutic purposes.
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Photochemical Internalisation (PCI) group
Sustained EKR inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy
Biochim Biophys Acta, 1830 (3), 2659-70
PubMed 23671927
Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity
Biochim Biophys Acta (in press)
PubMed 23643966
Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties
J Control Release, 168 (3), 317-326 (in press)
PubMed 23567040
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